One massive problem with scarce parking and no smart system to distribute it is that a lot of vehicles spend a lot of time driving in circles looking/waiting for a spot to turn over. If there were a system that was essentially a free lottery, it could avoid a lot of wasted time and pollution. You'd have to incentivize the occupant somehow though.
something like this:
1. Occupant is about to leave and sends an alert of near term availability. 2. N subscribers get the alert and enter the lottery, lottery executes, winner is selected, and winner is notified that they get the spot, no charge. The lottery could be weighted by karma, say the number of times that lottery participant has yielded a spot to others. 3. Occupant yields their spot to winner, and receives parking karma for next lotto. 4. Society benefits by less traffic, pollution.
Why go through the trouble of building an actual physical bee, when there are awesome 3d world and physics models that you could drop the bee brain into and it would have no idea the world was simulated. Seems like that would bee a lot easier debug. *cringe*
The study only sampled a subset of the genome (certain SNPs), there could be other variations in the genome that contribute even more. We simply can't tell from the study. All we can say is that this study suggests at least a quarter of the variation is explained by the subset of the genotype they have sampled.
No matter how "legitimate" it might look, whenever the highest executive in a country's government somehow manages to remove term limits, he has become a de facto dictator.
The higher you go in government the more important the concept of term limits become. Executives must have reason to fear that at some point they will have to answer for their actions to someone with the same level of authority they currently enjoy.
Chavez can crap roses and turn water into wine...as long as he maneuvers or succeeds in removing term limits...he's a dictator.
So these HIV patients will simultaneously be hosting HIV in CCR5wt cells providing a steady stream mutant HIV particles to try their luck at cracking CCR5null T cells.
Hopefully CCR5null is a real deal breaker for HIV or we might be creating the perfect situation for HIV to maximize its chances of overcoming that hurdle.
I think you hit the nail on the head. AMD seems to be trailing right now in performance and I suspect the reason is mostly process capability differences. I think AMD had a lead for a little while, mostly in their design (relatively cheap to achieve) but couldn't turn that lead into enough profit to fund more rapid advances in process shrinkage to maintain that lead ( a much more expensive endeavor). A good part of why they couldn't turn that lead into a decent reputation and lasting profit margins was industry inertia and Intel's very effective, perhaps sometimes underhanded, marketing.
What's even scarier is that AMD could fall far enough behind they eventually effectively fold. I don't think that would bode well for CPU prices.
Sometimes I think the enlightened consumer needs to think about the competetion aspect of the market. Given two options of equal or comparable value, give extra consideration to the little guy...you may benefit from the competetion later.
Any executive in power that does not honor the concept of term limits is a dictator, plain and simple.
I don't care if he shits flowers, cures the blinds and raises the dead. If he alters the constitution to eliminate term limits and plans to remain in power indefinitely, or even a very long time, he's a despot and a dictator.
Term limits are a crucial lynchpin concept of democracy. Without them, a leader need never fear answering for their actions.
What Chavez's effective elimination of term limits?
Term limits are one of the linch pins of democracy. Without them, no executive ever need fear answering for transgressions.
I think this alone makes Chavez a dictator. No matter how great his policies or effective his leadership, he is a dictator until he honors the previous constitutions terms limits.
Re:I thought "calorie restriction" study was debun
on
Longevity Gene Found
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· Score: 1
The short answer is no. Calorie restriction has not been debunked.
The long answer is "pubmed", search calorie restriction.
I can see the logic behind embracing a few closed components if the point is to amass a large enough user base to then bully the hardware vendors into opening specs (on pain of loosing that big linux market share). But there has to be a deadline, after a certain date, all new components are open source (accepted closed source components are grandfathered of course).
It will be fascinating to see what lengths society is willing to go to prohibit individuals from indulging in effortless reward. I can't wait to see copper wire on schedule I.
I also can't help but wonder if the war on drugs hasn't essentially shot society in the foot. By restraining self-destructive phenotypes, we have accumulated more in the population than we might have were the most dedicated allowed to pursue their end. Now along comes an unstoppable, uncontrollable form of cheap unlimited bliss and how many more are going to fall?
Maybe a VR game that's rich in the right textures and periodically blocks the lazy eye would be more effective than some passive graphical images. Get dopamine (fragging the Gabor wavelet monster = reward) involved and the learning goes faster.
The floor is not likely the place where this is happening. You're talking about a few square centimeters of acres of floor for brief periods of time. Not a big selective pressure. Remember that resistance comes at a cost, and bacteria on the floor wasting resources on a transient insult like a splatter of a/b are likely to become quickly overwhelmed by the more rapidly multiplying bacteria once the insult is washed away. Now on the other hand, in a human body awash with a/b, the selective pressure is much greater, the wild-type bacilla are wiped out, leaving only the mutant bacteria around. These mutant bacteria will spontaneously mutate back into wild-type, over a longish period of time, once the pressure of the a/b has vanished. This is telling of the cost of adaptation
The most remarkable implication of this is that, assuming they have observed no phenotype resulting from the GFP knockin, GFP really doesn't interfere measurably with any pathway, developmental, metabolic, or otherwise. Obviously there is the tiny resource cost associate with producing and elimating a useless inert bystander protein. GFP seems to be the ideal marker.
That is the biggest and perhaps only problem I have with the system. If it were trivial for an h1b to say "hey...these guys are screwin' me, I'm going to work Spacely Sprockets across the street", then we would have a fair system. As it is, they are essentially indentured servants.
The same technology that goes into the powerful centralized server can always be mass produced cheaply and sold in much greater volume to public at large. As long as that compute power and storage is available at a cheap price, software products will be created to exploit it.
Unless of course, the cost of producing a CPU attains the level of a mortgage, which it might someday.
The total system entropy has to increase but not the local entropy of a subsystem as long as there is an energy gradient to take advantage of.
Also, no one is going to live forever, just a bit longer than a paltry 70+/-30 years. Meteorites and falling pianos will eventually nail everyone.
There is an continuous unbroken stream of germline cells that got to you. That system somehow managed to escape the inevitable grip of entropy, didn't it?
Slashdot Mirror
One massive problem with scarce parking and no smart system to distribute it is that a lot of vehicles spend a lot of time driving in circles looking/waiting for a spot to turn over. If there were a system that was essentially a free lottery, it could avoid a lot of wasted time and pollution. You'd have to incentivize the occupant somehow though.
something like this:
1. Occupant is about to leave and sends an alert of near term availability.
2. N subscribers get the alert and enter the lottery, lottery executes, winner is selected, and winner is notified that they get the spot, no charge. The lottery could be weighted by karma, say the number of times that lottery participant has yielded a spot to others.
3. Occupant yields their spot to winner, and receives parking karma for next lotto.
4. Society benefits by less traffic, pollution.
FWIW, I thinks OruxMaps is great for offline navigation. It exists and is free.
Sounds like it could be.
posty frost
Why go through the trouble of building an actual physical bee, when there are awesome 3d world and physics models that you could drop the bee brain into and it would have no idea the world was simulated. Seems like that would bee a lot easier debug. *cringe*
The study only sampled a subset of the genome (certain SNPs), there could be other variations in the genome that contribute even more. We simply can't tell from the study. All we can say is that this study suggests at least a quarter of the variation is explained by the subset of the genotype they have sampled.
No matter how "legitimate" it might look, whenever the highest executive in a country's government somehow manages to remove term limits, he has become a de facto dictator.
The higher you go in government the more important the concept of term limits become. Executives must have reason to fear that at some point they will have to answer for their actions to someone with the same level of authority they currently enjoy.
Chavez can crap roses and turn water into wine...as long as he maneuvers or succeeds in removing term limits...he's a dictator.
So these HIV patients will simultaneously be hosting HIV in CCR5wt cells providing a steady stream mutant HIV particles to try their luck at cracking CCR5null T cells.
Hopefully CCR5null is a real deal breaker for HIV or we might be creating the perfect situation for HIV to maximize its chances of overcoming that hurdle.
I think you hit the nail on the head. AMD seems to be trailing right now in performance and I suspect the reason is mostly process capability differences. I think AMD had a lead for a little while, mostly in their design (relatively cheap to achieve) but couldn't turn that lead into enough profit to fund more rapid advances in process shrinkage to maintain that lead ( a much more expensive endeavor). A good part of why they couldn't turn that lead into a decent reputation and lasting profit margins was industry inertia and Intel's very effective, perhaps sometimes underhanded, marketing.
What's even scarier is that AMD could fall far enough behind they eventually effectively fold. I don't think that would bode well for CPU prices.
Sometimes I think the enlightened consumer needs to think about the competetion aspect of the market. Given two options of equal or comparable value, give extra consideration to the little guy...you may benefit from the competetion later.
Any executive in power that does not honor the concept of term limits is a dictator, plain and simple.
I don't care if he shits flowers, cures the blinds and raises the dead. If he alters the constitution to eliminate term limits and plans to remain in power indefinitely, or even a very long time, he's a despot and a dictator.
Term limits are a crucial lynchpin concept of democracy. Without them, a leader need never fear answering for their actions.
Ergo, Chavez is a dictator.
What Chavez's effective elimination of term limits?
Term limits are one of the linch pins of democracy. Without them, no executive ever need fear answering for transgressions.
I think this alone makes Chavez a dictator. No matter how great his policies or effective his leadership, he is a dictator until he honors the previous constitutions terms limits.
The short answer is no. Calorie restriction has not been debunked.
The long answer is "pubmed", search calorie restriction.
I can see the logic behind embracing a few closed components if the point is to amass a large enough user base to then bully the hardware vendors into opening specs (on pain of loosing that big linux market share). But there has to be a deadline, after a certain date, all new components are open source (accepted closed source components are grandfathered of course).
ok..I'll bite:
ROFLMAOL! RhettLivingston is accusing the NYT of bias! Maybe he should take the Sequoia trunk out of his own ass first.
It will be fascinating to see what lengths society is willing to go to prohibit individuals from indulging in effortless reward. I can't wait to see copper wire on schedule I.
I also can't help but wonder if the war on drugs hasn't essentially shot society in the foot. By restraining self-destructive phenotypes, we have accumulated more in the population than we might have were the most dedicated allowed to pursue their end. Now along comes an unstoppable, uncontrollable form of cheap unlimited bliss and how many more are going to fall?
This company has a graphical program that uses Gabor wavelet images to exercise the lazy eye:
http://www.neuro-vision.com/amblyopia/index.html
Maybe a VR game that's rich in the right textures and periodically blocks the lazy eye would be more effective than some passive graphical images. Get dopamine (fragging the Gabor wavelet monster = reward) involved and the learning goes faster.
The floor is not likely the place where this is happening. You're talking about a few square centimeters of acres of floor for brief periods of time. Not a big selective pressure. Remember that resistance comes at a cost, and bacteria on the floor wasting resources on a transient insult like a splatter of a/b are likely to become quickly overwhelmed by the more rapidly multiplying bacteria once the insult is washed away. Now on the other hand, in a human body awash with a/b, the selective pressure is much greater, the wild-type bacilla are wiped out, leaving only the mutant bacteria around. These mutant bacteria will spontaneously mutate back into wild-type, over a longish period of time, once the pressure of the a/b has vanished. This is telling of the cost of adaptation
The most remarkable implication of this is that, assuming they have observed no phenotype resulting from the GFP knockin, GFP really doesn't interfere measurably with any pathway, developmental, metabolic, or otherwise. Obviously there is the tiny resource cost associate with producing and elimating a useless inert bystander protein. GFP seems to be the ideal marker.
That is the biggest and perhaps only problem I have with the system. If it were trivial for an h1b to say "hey...these guys are screwin' me, I'm going to work Spacely Sprockets across the street", then we would have a fair system. As it is, they are essentially indentured servants.
The same technology that goes into the powerful centralized server can always be mass produced cheaply and sold in much greater volume to public at large. As long as that compute power and storage is available at a cheap price, software products will be created to exploit it.
Unless of course, the cost of producing a CPU attains the level of a mortgage, which it might someday.
The total system entropy has to increase but not the local entropy of a subsystem as long as there is an energy gradient to take advantage of.
Also, no one is going to live forever, just a bit longer than a paltry 70+/-30 years. Meteorites and falling pianos will eventually nail everyone.
There is an continuous unbroken stream of germline cells that got to you. That system somehow managed to escape the inevitable grip of entropy, didn't it?
Enough said.
"Lookie folks, you can download our source code, unlike those other evil opaque ne'erdowells."
What's to keep them from closing the source once everyone hops on the bandwagon? If there's no promise to keep it open in perpetuity, its worthless.
BAH!
Lets see the popo try and track down and prosecute 500k independant users. And for what? "Responding" to an email.
I doubt it.
Khoul...we'll hose down all the worm ridden boxes too.
Trace it back to last verifiable part of the header. The open relay that allowed the spam in the first place, or the ISP that did it.
One would not try and follow URLS, only open relays and ISP mail servers.
It won't take long for ISPs to respond and it won't take long for open relay to close.
The negative feedback is not going to destroy the network, it is temporary.