Reselling media is only evil and wrong this week. It'll be absolutely fine, 'innovative' and mainstream as soon as Amazon, Apple or Google starts doing it:
I'm not locked into the Apple ecosystem so it simply Does not work! I would have to use something that supports open standards.
The various Apple TVs have nice hardware, and It's easy enough to un-cripple the older versions (1&2) and run anything you like on them, including XBMC:
But no proper jailbreak yet for ATV3, AFAIK, so might go for a Pi if I was buying today. I suspect this is one product Apple would sell a lot more of if they made it hackable out of the box, especially internationally. It's silly to sell a product in the UK that offers MLB.TV (for all those dozens of British baseball fans) but not the BBC's very popular iPlayer service (though even an unhacked ATV is a good streamer for iPlayer content grabbed elsewhere with get_iplayer).
This prize has been 'offered' for over a decade, but for some reason has recently made the news. Occasionally someone bites, just to see what reaction they get, but trying to find mutually acceptable terms for a 'trial' is like arguing with the Timecube guy:
("All of these experiences confirm that evolution is the inverted fantasy based on the ancient Greek Gaea vitalism religion of 2,500 years ago that was disproven by the experiments, never overturned, of Dr. Francesco Redi in 1668.")
'While we might object on a number of grounds (efficacy being one of them) I'm sure they see DRM as a sensible thing to do to protect their business model by locking purchasers into their ecosystem.'
FTFY:-)
To be fair, I think Kobo uses Adobe DRM, which probably means there's some cross compatibility (but not with, e.g., Kindle, unless you strip the DRM).
...and got a master's degree, apparently. Is this the first Pope with a science qualification? Other papal trivia - he reportedly had a lung removed as a teenager, which obviously hasn't held him back.
'It has had somewhat of a renaissance in recent years as it forms the centrepiece of the Battle Proms Concerts that take place at stately homes around the UK. This is the only concert series known to play the piece with the full complement of 193 live cannon: modern technology has allowed it to be played using electronic firing devices, operated by the orchestra percussionist.'
'Beethoven had no illusions about its merits, and responded to similar criticism in his own time: "What I shit (scheisse) is better than anything you could ever think up!"' [a response that wouldn't be out of place on Twitter].
The only testimony they want is to determine if he's genuinely insane or just pretending. Either way, he's going to be locked up in prison or in a mental institution and I bet he's hoping for the latter in order to continue his "Joker" character fantasy.
The article notes: 'In an advisory that Holmes would have to sign if he enters an insanity plea, Sylvester didn't specify what type of drugs would be used but said the examination could include "medically appropriate" ones.'
Reports that a new, experimental aerosolized drug will be administered by court-appointed psychiatrist Dr. Jonathan Crane remained uncomfirmed at this time.
But is there really a difference between office in 2013, and office in 2002? It's been ten years of crazy awesome features that just don't matter.
I can now use more rows in Excel, but that's about the only change I've liked since Office 2000. Lots of irritating interface changes since then, but the fundamental annoyances are never addressed - Excel's auto conversion of any text that looks vaguely like a date into date format, silently corrupting the data unless you go out of your way to format the column as text only, is my absolute favourite:
get_iplayer doesn't have to defeat DRM - the iPlayer streams are DRM-free. You can also download DRM'd files via the BBC's iPlayer Desktop application, but that's a separate issue.
I don't think there's any parcticular need for a special package if you already have fast broadband. Most of the decent free TV is on iPlayer, which covers all the BBC channels and now has content from the major free to view commercial rivals:
You might also want to check out the ITV Player, 4od and Demand 5 sites (I rarely bother).
You can grab BBC (only) programmes from iPlayer with get_iplayer, which generates standard mp4 files you can play anywhere (finally a use for that Apple TV!):
There's some rather more useful and still reasonably up to date testing on Rob Galbraith's site for a few high-end SLRs (unfortunately no longer updated):
The raw data set is being used in a different way. In this type of sequencing, millions of short sequence 'reads' are aligned to a reference genome. A given locus may be covered by dozens of overlapping reads, as in the 'pileup' image here (second figure):
For detection of sequence variants (e.g. single base changes), the 'read depth' (height of the pileup) must be sufficient to call that variant confidently (allowing for heterozygosity, and the error rate of the technology), but it doesn't matter if that locus is covered 30 times or 100 times. Copy number variants, however, are detected by differences in read depth and, since read depth varies even across regions with the same copy number, you can't simply count the reads that align to a given locus - you need enough data (which may be more than a $6k genome run provides) to do the stats and look for regions of significant difference between genomes:
It looks to me like they'll be dual licensing. GPL3 is mentioned on the Kickstarter page, which presumably includes the deployed runtime libraries, so anything built with this version must also be FOSS. Anyone who wants to build a proprietary application will have to buy the commercial version. This is probably a good move for them. Although LiveCode pitched as an easy to use RAD, the current pricing is too high for casual developers:
A GPL edition will kill their education sales, but they should benefit from a much bigger user base and more potential future customers for the commercial version.
Sometimes, when you publish the code you used to develop new Biochemistry or Genetics solutions, you find that other scientists in other countries use your code to reverse engineer what you are working on - your results, if you will - to eliminate dead ends and publish a paper on what you invested years finding a solution for, but before you submit your paper that they "effectively" stole.
Fair enough, though sometimes getting out of the habit of 'releasing early, releasing often' can put academic developers on a slippery slope that ends with them closing the source. We use a well known (and excellent) suite of genomics software called GATK, originally MIT-licensed. Last year, the developers announced they were switching to a hybrid license, where the latest (unpublished) tools would only be available under closed source terms. The core (now 'lite') package would remain Open Source, and supposedly the new stuff would migrate to it over time as papers were published, etc. Now this has been retconned as a 'interim solution', and in all future versions the Open license will only apply to a basic framework with most of the useful stuff stripped out. Quite a few members of the genomics community are rather upset about the license changes, especially as there's a strong Open Source tradition in this field (a typical GATK data processing pipeline will depend on major components written by other developers that remain Open Source):
Slashdot Mirror
Reselling media is only evil and wrong this week. It'll be absolutely fine, 'innovative' and mainstream as soon as Amazon, Apple or Google starts doing it:
http://www.zdnet.com/amazon-lands-patent-on-marketplace-for-selling-on-used-digital-content-7000010917/
http://appleinsider.com/articles/13/03/07/apples-digital-content-resale-and-loan-system-could-allow-drm-transfers-between-end-users
Ncevy sbby! - Alneyngubgrc.
There's an Easter egg at rot13.com - if you cypher that text it actually gives you the rot13 of "In his house at R'lyeh, dead Cthulhu waits dreaming".
I'm not locked into the Apple ecosystem so it simply Does not work! I would have to use something that supports open standards.
The various Apple TVs have nice hardware, and It's easy enough to un-cripple the older versions (1&2) and run anything you like on them, including XBMC:
http://www.appletvhacks.net/
But no proper jailbreak yet for ATV3, AFAIK, so might go for a Pi if I was buying today. I suspect this is one product Apple would sell a lot more of if they made it hackable out of the box, especially internationally. It's silly to sell a product in the UK that offers MLB.TV (for all those dozens of British baseball fans) but not the BBC's very popular iPlayer service (though even an unhacked ATV is a good streamer for iPlayer content grabbed elsewhere with get_iplayer).
This prize has been 'offered' for over a decade, but for some reason has recently made the news. Occasionally someone bites, just to see what reaction they get, but trying to find mutually acceptable terms for a 'trial' is like arguing with the Timecube guy:
http://ncse.com/rncse/25/5-6/life-science-prize
Here's the prize page on Mastropaolo's site:
http://www.josephmastropaolo.com/prize.html
("All of these experiences confirm that evolution is the inverted fantasy based on the ancient Greek Gaea vitalism religion of 2,500 years ago that was disproven by the experiments, never overturned, of Dr. Francesco Redi in 1668.")
Why would you want to go "back a long, long time" when the current UI is the product of 20 years of evolution and natural selection?
Well, it certainly isn't the product of Intelligent Design!
This would have never fooled a person with the Maker Mentality. :)
You cynics! This device is so sensitive that "in real-world situations, detection levels are in the pictogram range and below":
http://cominfosystems.com/Documents/Cominfo_ATSC_Brochure.pdf
'While we might object on a number of grounds (efficacy being one of them) I'm sure they see DRM as a sensible thing to do to protect their business model by locking purchasers into their ecosystem.'
FTFY :-)
To be fair, I think Kobo uses Adobe DRM, which probably means there's some cross compatibility (but not with, e.g., Kindle, unless you strip the DRM).
...and got a master's degree, apparently. Is this the first Pope with a science qualification? Other papal trivia - he reportedly had a lung removed as a teenager, which obviously hasn't held him back.
Tchaikovsky used cannons in his percussion section. Beat that, Beethoven.
http://en.wikipedia.org/wiki/Wellington's_Victory
'It has had somewhat of a renaissance in recent years as it forms the centrepiece of the Battle Proms Concerts that take place at stately homes around the UK. This is the only concert series known to play the piece with the full complement of 193 live cannon: modern technology has allowed it to be played using electronic firing devices, operated by the orchestra percussionist.'
'Beethoven had no illusions about its merits, and responded to similar criticism in his own time: "What I shit (scheisse) is better than anything you could ever think up!"' [a response that wouldn't be out of place on Twitter].
He originally scored it for a giant robot ( http://en.wikipedia.org/wiki/Panharmonicon ), but they couldn't build one big enough at the time.
The only testimony they want is to determine if he's genuinely insane or just pretending. Either way, he's going to be locked up in prison or in a mental institution and I bet he's hoping for the latter in order to continue his "Joker" character fantasy.
The article notes: 'In an advisory that Holmes would have to sign if he enters an insanity plea, Sylvester didn't specify what type of drugs would be used but said the examination could include "medically appropriate" ones.'
Reports that a new, experimental aerosolized drug will be administered by court-appointed psychiatrist Dr. Jonathan Crane remained uncomfirmed at this time.
Even attempting to activate the manual override can be confusing for those without prior unix experience:
http://xkcd.com/912/
This is nothing new. Steve Ballmer first tested chair destruction DRM at Microsoft nearly a decade ago.
But is there really a difference between office in 2013, and office in 2002? It's been ten years of crazy awesome features that just don't matter.
I can now use more rows in Excel, but that's about the only change I've liked since Office 2000. Lots of irritating interface changes since then, but the fundamental annoyances are never addressed - Excel's auto conversion of any text that looks vaguely like a date into date format, silently corrupting the data unless you go out of your way to format the column as text only, is my absolute favourite:
http://www.biomedcentral.com/1471-2105/5/80
Inevitably there is a DNA editing mode for Emacs, though unfortunately there don't seem to be any 'insert tail' commands available:
http://www.mahalito.net/~harley/elisp/dna-mode.el
...by 'DNA 2.0', which seems to hold an absurdly broad patent on DNA editors:
http://holmansbiotechipblog.blogspot.co.uk/2012/12/dna-20-sues-genome-compiler-corp-for.html
get_iplayer doesn't have to defeat DRM - the iPlayer streams are DRM-free. You can also download DRM'd files via the BBC's iPlayer Desktop application, but that's a separate issue.
I don't think there's any parcticular need for a special package if you already have fast broadband. Most of the decent free TV is on iPlayer, which covers all the BBC channels and now has content from the major free to view commercial rivals:
http://www.bbc.co.uk/iplayer/
You might also want to check out the ITV Player, 4od and Demand 5 sites (I rarely bother).
You can grab BBC (only) programmes from iPlayer with get_iplayer, which generates standard mp4 files you can play anywhere (finally a use for that Apple TV!):
http://www.infradead.org/get_iplayer/html/get_iplayer.html
Some US TV sites can be accessed by methods like this (or get a VPN):
http://xtremisreaction.wordpress.com/2011/01/08/how-to-watch-the-daily-show-with-jon-stewart-in-the-uk/
http://xtremisreaction.wordpress.com/2013/01/05/how-to-watch-hulu-and-us-television-in-the-uk/
There's some rather more useful and still reasonably up to date testing on Rob Galbraith's site for a few high-end SLRs (unfortunately no longer updated):
http://www.robgalbraith.com/bins/multi_page.asp?cid=6007
Lexar cards are included, up to 600x SDHC, and 1000x CF. XQD cards are the real speed demons now, of course.
British youth aren't exactly any better.
http://www.youtube.com/watch?v=_CwfCBa6PSM
'Epic war fail'.
Catchy tune at the end too, that's a real earworm, I'll be whistling that one all the way to the firestorm they are going to unleash on me.
It's OK, but really not in the same league as Excellent Horse-Like Lady:
http://www.youtube.com/watch?v=v5tkXgw2OMY
The raw data set is being used in a different way. In this type of sequencing, millions of short sequence 'reads' are aligned to a reference genome. A given locus may be covered by dozens of overlapping reads, as in the 'pileup' image here (second figure):
http://blog.goldenhelix.com/?p=490
For detection of sequence variants (e.g. single base changes), the 'read depth' (height of the pileup) must be sufficient to call that variant confidently (allowing for heterozygosity, and the error rate of the technology), but it doesn't matter if that locus is covered 30 times or 100 times. Copy number variants, however, are detected by differences in read depth and, since read depth varies even across regions with the same copy number, you can't simply count the reads that align to a given locus - you need enough data (which may be more than a $6k genome run provides) to do the stats and look for regions of significant difference between genomes:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752127/
95% of users of Photoshop didn't pay for it either.
Hardly surprising, considering how blatant some of the warez sites are getting nowadays:
http://www.adobe.com/downloads/cs2_downloads/index.html
It looks to me like they'll be dual licensing. GPL3 is mentioned on the Kickstarter page, which presumably includes the deployed runtime libraries, so anything built with this version must also be FOSS. Anyone who wants to build a proprietary application will have to buy the commercial version. This is probably a good move for them. Although LiveCode pitched as an easy to use RAD, the current pricing is too high for casual developers:
http://www.runrev.com/store/
A GPL edition will kill their education sales, but they should benefit from a much bigger user base and more potential future customers for the commercial version.
Sometimes, when you publish the code you used to develop new Biochemistry or Genetics solutions, you find that other scientists in other countries use your code to reverse engineer what you are working on - your results, if you will - to eliminate dead ends and publish a paper on what you invested years finding a solution for, but before you submit your paper that they "effectively" stole.
Fair enough, though sometimes getting out of the habit of 'releasing early, releasing often' can put academic developers on a slippery slope that ends with them closing the source. We use a well known (and excellent) suite of genomics software called GATK, originally MIT-licensed. Last year, the developers announced they were switching to a hybrid license, where the latest (unpublished) tools would only be available under closed source terms. The core (now 'lite') package would remain Open Source, and supposedly the new stuff would migrate to it over time as papers were published, etc. Now this has been retconned as a 'interim solution', and in all future versions the Open license will only apply to a basic framework with most of the useful stuff stripped out. Quite a few members of the genomics community are rather upset about the license changes, especially as there's a strong Open Source tradition in this field (a typical GATK data processing pipeline will depend on major components written by other developers that remain Open Source):
http://biomickwatson.wordpress.com/2013/01/28/gatk-why-it-matters/
http://blastedbio.blogspot.co.uk/2013/01/free-for-non-commercial-academic-use.html