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Testosterone Increasingly Being Used To Fight Aging In Men

An anonymous reader writes: In this time of advanced technology, our battle against aging isn't going well. Lifespan has been improved quite a bit through halting numerous diseases and improving nutrition, but medical science is struggling to slow the gradual wear and tear that builds up as we get older. Cutting edge treatment theories are all hellishly complex, so many men are turning to a solution that's been with us for 80 years: testosterone. Clinics are popping up around the U.S. that prescribe no actual medicine, but instead hand out testosterone and supplements. "In 2013, 14,000 kilograms of testosterone were sold in the United States. That might not sound like much, but a typical adult male has just 0.000000035 kilograms of testosterone floating around in his bloodstream. There is a lot of extra T in the hormonal composition of the country—and it only accounts for the legal sales."

John Hoberman, professor and author, calls this new medical model "client-centered libertarian medicine." He says, "Once upon a time, respectable society feared contamination by illegal and disreputable drugs that were consumed by social deviants. Now regulators are concerned about a growing demand for legal drugs that serve socially sanctioned goals such as productivity, physical attractiveness, and sexual viability. The 'threat' posed by such drugs originates in the very system of values that sanctions their use, and it is a paradox that has put regulators in an untenable position."

201 comments

  1. Is it low T? by RogueWarrior65 · · Score: 5, Funny

    No, it's low T&A.

    1. Re:Is it low T? by cayenne8 · · Score: 1, Informative

      No, it's low T&A.

      Oh man, I wish I had mod points today.

      I think you win with this one today!!

      :)

      --
      Light travels faster than sound. This is why some people appear bright until you hear them speak.........
    2. Re:Is it low T? by Anonymous Coward · · Score: 0

      Some times I swear, I need a day just for me to lay
      With some T and A,
      But the way we, the way we do is deeper
      Baby straight up chemistry DNA
      Make me wanna give you every dollar out my B of A

    3. Re:Is it low T? by Anonymous Coward · · Score: 0

      Can someone explain that joke for those of us non-Americans who don't get it?

    4. Re:Is it low T? by demonlapin · · Score: 4, Informative

      T&A = tits and ass; the implication is that men are seeking treatment because they aren't getting laid as much.

    5. Re:Is it low T? by BarbaraHudson · · Score: 1

      For the GP: The expression "T & A " gained popularity with TV programs that relied on "tits and ass" more than actual acting skills and plot. Charlie's Angels, etc.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    6. Re:Is it low T? by dheltzel · · Score: 2

      Wait! You're saying Charlie's Angels had a plot?

      Off to watch some reruns to verify this . . . .

    7. Re:Is it low T? by Anonymous Coward · · Score: 0

      T&A -> titties and ass

    8. Re:Is it low T? by Anonymous Coward · · Score: 0

      Wait! You're saying Charlie's Angels had a plot?

      Who cared if it had a plot?

    9. Re:Is it low T? by Talderas · · Score: 1

      I don't want a plot of land. I want HUGE TRACTS of land.

      --
      "Lack of speed can be overcome. In the worst case by patience." --Znork
    10. Re:Is it low T? by RogueWarrior65 · · Score: 2

      Here's a musical number that explains it.
      https://www.youtube.com/watch?...

    11. Re:Is it low T? by Anonymous Coward · · Score: 2, Informative

      It should be pointed out that, past about age 65 - 70, men can get plenty of tail as there are many more women alive after then than men.

      Woo Hoo!

    12. Re:Is it low T? by B33rNinj4 · · Score: 1

      The best way to fight aging is to date a girl half you age.

    13. Re:Is it low T? by Anonymous Coward · · Score: 0

      They can't bury you on large tracts of land, they can only bury you on a small plot. Smaller if you are cremated.

    14. Re:Is it low T? by Anonymous Coward · · Score: 0

      True. I'm 68 and dating a 37 y.o.

    15. Re:Is it low T? by Anonymous Coward · · Score: 0

      Unfortunately for women over 65, men over 65 are most interested in women (way) under 65.

  2. Hello, Priceline? by Anonymous Coward · · Score: 0

    I need to book a flight to Dr. Paul Campion’s office, stat!

  3. "client-centered libertarian medicine" by Anonymous Coward · · Score: 2, Insightful

    AKA, under-regulated.

    1. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      Why shouldn't an adult American male have the right to turn his own testes into shrivelled raisins through the excessive use of testosterone?

    2. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      By the same token why shouldn't an adult American male have the right to turn himself into a gentle little buttercup by taking Lipitor, drinking tap-water riddled with phytoestrogens and drinking soy products?

      To each his own.

    3. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      Testosterone Increasingly Being Used To Fight Aging In Men

      So this is like bumfights, but with old guys? They give these aging men testosterone, get them all rippeded and aggro and toss them in the ring to beat each others brains out for our amusementainment?

    4. Re:"client-centered libertarian medicine" by Anonymous Coward · · Score: 1

      AKA crooks

    5. Re: "client-centered libertarian medicine" by JaredOfEuropa · · Score: 2, Interesting

      That goes for cocaine as well, and any other substance abuse.

      I think anyone should have the right to snort, shoot or smoke anything they like, and that the government should curtail the use of drugs only in exceptional cases:
      - Use of the substance causes a clear danger to others (like drugs that turn you into an axe wielding maniac after 1 hit)
      - Use of the substance causes a clear danger to users (such as highly addictive drugs or drugs causing damage: marihuana / alcohol and minors)

      In such cases the government should step in, if:
      - The number of problem cases far outweighs the number of normally functioning users, and
      - The proposed controls are effective in reducing the number of problem cases, and
      - The effects of the proposed controls outweigh the undesired side effects of the controls (such as the impact on responsible users)

      Of course, one man's undesired side effects (such as regular pot smokers being jailed) are another man's bonus side effects.

      --
      If construction was anything like programming, an incorrectly fitted lock would bring down the entire building...
    6. Re: "client-centered libertarian medicine" by ColdWetDog · · Score: 1

      If you don't stop making sense you will not be allowed to post on Slashdot in the future. You certainly won't be allowed to run for office.

      "Man is not a rational animal, he is a rationalizing animal".
      Heinlein

      --
      Faster! Faster! Faster would be better!
    7. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      to turn himself into a gentle little buttercup...drinking tap-water riddled with phytoestrogens

      The funny thing about all of this mess, is that everyone assumes the estrogen like compounds coming from water sources and plastics, etc., will turn people into whatever female stereotype they have in mind. Yet studies of some of the compounds are found to cause people, especially young boys, to become more aggressive and impulsive.

    8. Re: "client-centered libertarian medicine" by sexconker · · Score: 1

      to turn himself into a gentle little buttercup...drinking tap-water riddled with phytoestrogens

      The funny thing about all of this mess, is that everyone assumes the estrogen like compounds coming from water sources and plastics, etc., will turn people into whatever female stereotype they have in mind. Yet studies of some of the compounds are found to cause people, especially young boys, to become more aggressive and impulsive.

      You'd be impulsive and subject to mood swings if you had wildly fluctuating hormone levels that your body wasn't able to regulate.
      See women, hysteria, etc. And that's under normal conditions. Men's hormone levels fluctuate much more erratically than women's (again, under normal conditions). Add in soy, plastic, contaminated drinking water, and all the other unnatural sources of estrogens and it's really no surprise that men are fucked up hormonally and are upset about it. Or are you telling me you wouldn't be upset if you started growing tits and then got cancer in them because your environment is heavily polluted with estrogens?

      And of course, when it's women who are subject to hormonal mood swings, you're supposed to be sensitive and understanding. They get pre-menstrual syndrome. But when men have the exact same symptoms you have to fight to get it recognized as anything other than aggression, depression or some other "problem" that you can blame or stigmatize the man for. And when you do finally get someone to recognize the cause, they brand it "irritable male syndrome".

    9. Re: "client-centered libertarian medicine" by AntiAntagonist · · Score: 1

      I'm not as familiar with the effects on humans, but it has had a noticeable effect on fish populations: http://www.scientificamerican....

    10. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      - Use of the substance causes a clear danger to others (like drugs that turn you into an axe wielding maniac after 1 hit) Like drugs that if misused lead to superbugs that are immune to all known antibiotics.

    11. Re: "client-centered libertarian medicine" by Anonymous Coward · · Score: 0

      As long as the label states it as such, along with all the other possible side effects and clinical studies, I'm fine with it. But we all know that's not what's happening.

  4. Not affecting life expectancy in a positive way by Anonymous Coward · · Score: 0

    While this might seem like it reduces aging, US is 45th or 46th in life expectancy globally. Other countries are not using these treatments, and men live an extra 10-12 years in some of them

    1. Re:Not affecting life expectancy in a positive way by Anonymous Coward · · Score: 0

      Source please.

      Nevermind. You're absolutely wrong. Other countries are using a lot of these products. eg: Nebido is legal throughout Europe but not the USA.

    2. Re:Not affecting life expectancy in a positive way by Anonymous Coward · · Score: 1

      List_of_countries_by_life_expectancy on wikipedia. We are 36 or so based on WHO and 40+ based on any other stat. Also, a product being legal does not make it popular or prescribed to the majority

    3. Re:Not affecting life expectancy in a positive way by Paradise+Pete · · Score: 1

      It's not being taken to extend life, it's being taken in the hope that it makes the person feel younger and stronger.

    4. Re:Not affecting life expectancy in a positive way by Beyond_GoodandEvil · · Score: 2

      While this might seem like it reduces aging, US is 45th or 46th in life expectancy globally. Other countries are not using these treatments, and men live an extra 10-12 years in some of them
      Ugg, So much wrong info. 1st US is 36th in life expectancy, 2nd our neighbors to the north, Canada lives 2.7 years longer and they're #11. So as you can see there's a not really a difference in living 3 more years yet those 3 years span 25 other countries. Taking these treatments isn't going to kill you that much faster.

      --
      I laughed at the weak who considered themselves good because they lacked claws.
    5. Re:Not affecting life expectancy in a positive way by sexconker · · Score: 2

      List_of_countries_by_life_expectancy on wikipedia

      Flawed list using flawed data that, even if you trusted it, doesn't properly account for differences in the tracking of infant mortality.

  5. Well considering that many of us have low T by Anonymous Coward · · Score: 1

    What percentage of Americans has artificially low testosterone as a result of statin drugs? A little extra T might be good for an emasculated male population. How many millions of American men were chemically castrated by doctors who convinced them that cholesterol wasn't necessary? Glad to hear that men are at least interested in becoming male again.

    1. Re:Well considering that many of us have low T by jellomizer · · Score: 5, Insightful

      I expect many people are getting diagnosed with Low T so they can get more bulked up at the gym faster.
      There is so much talk about an unrealistic body image for women. But the same thing is happening for men. We are expected to have 6 pack abs, Peck mussels that can dance, and arms thicker than your waist.
      We expect to look like a Greek Statue (while the ancient greeks made their statues, based on an exaggerated body image). While men should look more like that of Roman statues (based on actual body appearances)
      So we go to the doctor and explain that we have such problems and we get the prescription of T.

      Sure there are good reasons too, but I expect a lot of men are getting it where it isn't really needed.

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    2. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 3, Interesting

      Sorry but no. First off, body builders aren't taking testosterone. There are much better steroids out there (or "gear" in musclehead parlance). Nobody who wants to bulk up would ever take testosterone. It's just not worth it in terms of expense, difficulty of acquisition and frequency of dosing.

      Secondly, you should look into the three major global testosterone studies. There have been 3 studies since the 1980's. The results: Testosterone levels in the developed world (but not emerging markets) have plunged almost 30% over the past few decades.

      That means you. (Assuming you're of the XY persuasion).

      You can blame a combination of water recycling (and women on the pill), ubiquitous soy in our foods, statin drugs, plastic water bottles and more.

      The irrefutable evidence is that testosterone levels in America, Europe and Japan have tanked. The question that policy makers and physicians are asking is, "should we care?"

      I think probably, yes. But to each his own.

    3. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      There is so much talk about an unrealistic body image for women. But the same thing is happening for men. We are expected to have 6 pack abs, Peck mussels that can dance, and arms thicker than your waist.

      And the thing is that unrealistic body image for women is more easily attainable as it's mostly due to diet. For men though it takes diet and a lot of time at the gym doing lots of specific exercises to get the unrealistic male body image, plus they're still expected to pull in a high salary as well.

    4. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      I think probably, yes.

      My chemical company stocks say no, though, and they pay the government lots to make sure they can pump you full of xenoestrogens like BPA. BTW, be sure to wear gloves when you get your receipt, I'd say to wash your hands after handling them but soaps apparently accelerates absorption of the BPA into the skin.

    5. Re:Well considering that many of us have low T by pr0nbot · · Score: 2

      Dancing peck mussels was how I discovered I was allergic to seafood :(

    6. Re:Well considering that many of us have low T by linear+a · · Score: 5, Interesting

      Curious about those studies. Were they age-controlled or survey of the general (ageing) population?

    7. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      All of this is true. And by the way, falling t-levels are extremely bad in northern Europe because of birth control and the type of water-purification systems we use. We are all drinking and absorbing large quantities of oestrogens.

    8. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      I am going today to see if I can try Testosterone Replacement Therapy. I am 5' 11" and weight 185 lbs. I am not a body-builder (though I do enjoy working out). I ordered some lab work and it indicated that my testosterone levels were that of a 65 year old man, I am 35 with one child and another on the way. I work a job that expects me to be in the office 6-7 days a week for 12+ hours. My wife stays at home to raise our child (soon to be children). I cannot just change my job without drastically affecting my family. I am moody, have low energy, have low focus, am easily distracted, am losing motivation, have low libido, am tired, am stressed, and am starting to feel run down. I have already changed my diet and increased the amount I sleep each day. I try to get motivated to work out but it usually doesn't happen and takes time away from my wife and daughter.

      So, I am going to see if TRT makes a difference. If so, great. If not, then I will stop. It has nothing to do with bulking up and instead has to do with lifestyle and wanted to be on top of my game for life in general. If that means that people turn their nose up at my chosen therapy fine. But there are some many people medicating to increase their quality of life and medicating to improve their mental game that are not clinical. Yet this treatment option, trying to get your Man hormones into a range normal for your age is mocked. I honestly don't get it.

    9. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      Sure there are good reasons too...

      Such as?

    10. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      While there are many statues that feature 'Heroic' proportions, on of the interesting things about looking at older art is the relative frequency of ugly, fat, and otherwise everyday people depicted.

    11. Re:Well considering that many of us have low T by Motard · · Score: 1

      ...Peck mussels that can dance...

      I think only birds have peck muscles.

    12. Re:Well considering that many of us have low T by GrumpySteen · · Score: 2

      I work a job that expects me to be in the office 6-7 days a week for 12+ hours. ...
      I am moody, have low energy, have low focus, am easily distracted, am losing motivation, have low libido, am tired, am stressed, and am starting to feel run down.

      Stress causes testosterone levels to drop. Get a job that doesn't require working 72-84 hours a week and your testosterone levels will probably go back to normal on their own without adding to your risk of strokes, heart attacks and blood clots.

    13. Re:Well considering that many of us have low T by yabos · · Score: 1

      Bodybuilders who know what they're doing will base their cycle off of testosterone and stack with others such as tren, etc.. Other steroids have stronger androgenic and anabolic effects but test works better to keep your natural libido and energy since it's what your body expects to be there.

    14. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      You seem to elided this sentence from OP post, " I cannot just change my job without drastically affecting my family. "

    15. Re: Well considering that many of us have low T by Anonymous Coward · · Score: 0

      I suggest that you look into hcg. I've been taking it for years. It can raise your t levels without damaging fertility, plus you don't have to jab yourself in the leg over and over. I get mine from a company called ITC Pharmacy and my labs indicate that my t levels are excellent. It costs me about $60 per month.

    16. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      Yeah, I don't understand the negativity around testosterone treatments. It's not as if doctors have never prescribed testosterone injections before. The only thing that's recently new is the topical applications. The fact is low-T can cause a myriad problems affecting all parts of your system. The attitude against helping men with low-T (the number of which are worryingly increasing in industrialized countries) is perplexing. Its like the attitude that some people have against prescribing painkillers for people who have chronic pain. They just expect those people to suffer all because of the possibility that someone will abuse the system and get painkillers illegally. The sentiment seems to be the same here in this thread.

        I would, however, recommend that you get a Prostate-Specific Antigen (PSA) test and also get your heart checked out before embarking on a testosterone course of treatment. Of course, your doctor should already tell you this, but unfortunately some don't.

    17. Re:Well considering that many of us have low T by mjm1231 · · Score: 1

      During that same time period, lifespans and overall health have improved. So what information leads you to think this constitutes a health problem?

      --
      Ideology: A tool used primarily to avoid the bother of thinking.
    18. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      Why are you posting if you have ZERO idea what you are talking about? Test is the bread and butter in bodybuilding use. Yes, there are a lot of other steroids but test is very commonly used either alone or as a "base" in conjuction with others. Expense and difficulty of acquisition?! Test is among the cheapest and easiest to acquire.

    19. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      > Peck mussels that can dance

      I think he was referring to 'Pecking dancing mussels' such as Oyster Catchers do.

    20. Re:Well considering that many of us have low T by BarbaraHudson · · Score: 1

      So, dropping dead from the stress of too many hours worked won't drastically affect his family?

      "I work a job that expects me to be in the office 6-7 days a week for 12+ hours"

      "I am moody, have low energy, have low focus, am easily distracted, am losing motivation, have low libido, am tired, am stressed, and am starting to feel run down. I have already changed my diet and increased the amount I sleep each day. I try to get motivated to work out but it usually doesn't happen"

      How do you expect to be motivated for work under such conditions? People are not machines; you're finding that out; more testosterone won't help you cope with such situations. Many of us have found out the hard way that 12+ hours a day doing something we love eventually turns into 12+ hours of hate and resentment.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    21. Re:Well considering that many of us have low T by Win0ver · · Score: 1

      Wow, those things about bodybuilders... they're all wrong. Really wish I had mod points. It's basically the exact opposite: used all the time, cheap, easy to acquire.

    22. Re:Well considering that many of us have low T by Graydyn+Young · · Score: 1

      I expect many people are getting diagnosed with Low T so they can get more bulked up at the gym faster.

      Some men might try this, but it won't work. Like most of the endocrine system, testosterone is regulated through a feedback system. Basically, if you ingest testosterone, your blood testosterone won't go up, you'll just be reducing the amount of testosterone signalling hormone that your body produces. The only case where ingesting test will actually increase your test levels, is if you have a legitimate glandular problem.

      When juice boxes use testosterone, it's a bit different. They are injecting heroic doses in order to overwhelm this system. If you tried to take that amount of test in a pill, it would be very harmful.

    23. Re:Well considering that many of us have low T by Anonymous Coward · · Score: 0

      THANK YOU!

  6. Really, Slashdot? by Greyfox · · Score: 5, Insightful

    Tunning into an infomercial food suppliment quackery site, are we? This is a new low, even for slashdot. Did Dice put you up to this or are you just giving free advertising to any shit that comes along now?

    --

    I'm trying to teach myself to set people on fire with my mind... Is it hot in here?

    1. Re:Really, Slashdot? by Anonymous Coward · · Score: 2, Insightful

      According to the comments, Slashdot reaches a new low with every single article they post.

    2. Re:Really, Slashdot? by Pfhorrest · · Score: 1

      Which is totally possible if the site is in gradual decline.

      --
      -Forrest Cameranesi, Geek of all Trades
      "I am Sam. Sam I am. I do not like trolls, flames, or spam."
    3. Re:Really, Slashdot? by GrumpySteen · · Score: 2

      Dammit! Just look at this comment! Slashdot has reached a new low!

  7. Not medicine? by internerdj · · Score: 5, Insightful

    Estrogen given to a patient is medicine, what is different for testosterone? Is he making some sort of Paleo marketing ploy or does he mean that the product isn't going through the medical approval process?

    1. Re:Not medicine? by Enry · · Score: 2

      Because lady parts

    2. Re:Not medicine? by PvtVoid · · Score: 1

      Estrogen replacement therapy in women (about the closest equivalent to testosterone therapy in men) was shown to increase the risk of breast cancer.

      There ain't no such thing as a free lunch. People get old, and there is no magic bullet to stop it.

    3. Re:Not medicine? by Anonymous Coward · · Score: 0

      People get old, and there is no magic bullet to stop it.

      Yet.

    4. Re:Not medicine? by Anonymous Coward · · Score: 0

      Over 200 studies on testosterone therapy, and none have shown any correlation with any form of cancer. With the one exception of those who already have prostate cancer and can see faster tumor growth on testosterone therapy.

      And regarding people getting old / anti-aging drugs ... You haven't seen anything yet.

    5. Re:Not medicine? by gstoddart · · Score: 5, Funny

      People get old, and there is no magic bullet to stop it.

      Well ... technically it doesn't need to be magic to stop you from getting old.

      --
      Lost at C:>. Found at C.
    6. Re:Not medicine? by Anonymous Coward · · Score: 0

      Mod parent up for dead-on sociopolitical analysis.

    7. Re:Not medicine? by BarbaraHudson · · Score: 3, Informative

      It only showed an increased breast cancer risk for those taking estrogen + progesterone. Estrogen-only treatment resulted in a reduction of breast cancer incidence.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    8. Re:Not medicine? by bobaferret · · Score: 1

      subtle... and funny..

    9. Re:Not medicine? by Anonymous Coward · · Score: 0

      Testosterone given to a trans man for example is medicine. I'm sure there are other actual endocrine disorders that would indicate its use.

      I'm guessing the concern is overuse for things that are mostly cosmetic (muscleheads, others who want increased metabolism at risk of heart disease, etc). So, probably that the product is going through a dubious medical process or as you suggested none at all. Something tells me there's sloppy or no blood work going on here. So probably a combination of both: dubious medicine combined with Paleo woo.

      They used to think estrogen HRT was an effective and safe way to deal with menopause, but it causes more problems than it solves, so old age is no longer a reason to undergo estrogen HRT.

      Turns out something similar happens in men leading to "grumpy old man syndrome." Likewise, I'm guessing using testosterone HRT is causing more problems that it solves.

      Somewhere in that Red Dwarf parallel universe where Lister got pregnant, somebody is seriously suggesting that healthy people take estrogen to enhance one's female figure and keep one virile into old age.

      Everyone wants a magic pill with fountain of youth extract and as another commenter mentioned, give us the physique of Greek gods and goddesses.

    10. Re:Not medicine? by Squiddie · · Score: 1

      Fuck, I accidentally downmoded you. Posting to undo.

    11. Re:Not medicine? by ColdWetDog · · Score: 1

      Juan Ponce de Leon? Is that you?

      --
      Faster! Faster! Faster would be better!
    12. Re:Not medicine? by ColdWetDog · · Score: 1

      And a clear increase in uterine cancers.

      You can't win.
      You can't break even.
      You have to play the game.

      --
      Faster! Faster! Faster would be better!
    13. Re:Not medicine? by BarbaraHudson · · Score: 0

      Only for women who haven't had a hysterectomy :-) Can't get cancer in something you haven't got.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    14. Re:Not medicine? by rogoshen1 · · Score: 2

      well to be honest, any old bullet with sufficient velocity stops aging in its tracks -- especially if applied directly to forehead.

    15. Re:Not medicine? by Anonymous Coward · · Score: 0

      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      head on apply directly to the forehead..
      https://www.youtube.com/watch?v=UAbAIpZG7II

    16. Re:Not medicine? by Immerman · · Score: 1

      >People get old, and there is no magic bullet to stop it.

        Sure there is. In fact you don't even need a magic bullet - pretty much any bullet is capable of preventing you from getting old if it's applied soon enough.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    17. Re:Not medicine? by jbengt · · Score: 1

      But the medicine does come with warnings that it may cause men to grow breasts.

    18. Re:Not medicine? by BarbaraHudson · · Score: 1

      They used to think estrogen HRT was an effective and safe way to deal with menopause, but it causes more problems than it solves, so old age is no longer a reason to undergo estrogen HRT.

      The WHI study (the one that caused everyone to panic) has since come under a LOT of criticism, much of it valid. For example, the women were taking Premarin (derived from horse piss) instead of estradiol (estrace). Premarin contains 3 different estrogens, only one of which is produced in humans. Also, the study didn't control for use of progesterone. And the majority of participants were either smokers or former smokers (hey, good way to bias the results).

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    19. Re:Not medicine? by Anonymous Coward · · Score: 0

      Which is a plus for stay at home dads. Males can lactate too if you spend a couple months working at it.

    20. Re:Not medicine? by Anonymous Coward · · Score: 0

      I'm biologically male and take estrogen :) (and progesterone and spironolactone)

  8. Article did not discuss downsides by gurps_npc · · Score: 4, Insightful
    They couldn't mention the downside of taking testerone?

    It decreases fertility, enlarges the prostate, and causes other issues.

    --
    excitingthingstodo.blogspot.com
    1. Re:Article did not discuss downsides by Dr+J.+keeps+the+nerd · · Score: 4, Funny

      Other side effects include aggression and being banned from sports competitions.

    2. Re:Article did not discuss downsides by thoriumbr · · Score: 4, Insightful

      I don't think aging people on their 70's will care much about fertility...

    3. Re:Article did not discuss downsides by GameboyRMH · · Score: 1

      I'm wondering how the hell testosterone is supposed to increase your lifespan. I've only seen evidence that suggests testosterone will decrease your lifespan.

      --
      "When information is power, privacy is freedom" - Jah-Wren Ryel
    4. Re:Article did not discuss downsides by xanthines-R-yummy · · Score: 0

      You'd be surprised, actually...

    5. Re:Article did not discuss downsides by rjstegbauer · · Score: 2

      ...as well as an increased risk of heart attack.

      http://abcnews.go.com/blogs/he...

      I'll pass, since I already have heart disease in my family history. You can choose otherwise.

    6. Re:Article did not discuss downsides by aliquis · · Score: 3, Insightful

      Some people argue dying at 75 is good.

      Some people would rather the physically and mentally fit in their 80-100 and then die at 100 rather than ill 80-120 and die at 120.

    7. Re:Article did not discuss downsides by Anonymous Coward · · Score: 1

      Other downsides to be eliminated before we can get our hands on it:
      1. Increase libido
      2. increased lean body mass
      3. reduced incidence of depression/improved self image
      4. increased motivation/drive

      Negatives only come into play above a certain T level that is not involved in therapeutic treatments.

    8. Re:Article did not discuss downsides by NostalgiaForInfinity · · Score: 4, Insightful

      Low testosterone and high testosterone each correlate both with some desirable and some undesirable factors, and almost nothing can be said about causality.

      Your best bet is to exercise, eat better, and lose weight; that clearly has health benefits and will also naturally raise your testosterone levels.

    9. Re:Article did not discuss downsides by billewood · · Score: 3, Interesting

      There is considerable evidence that testosterone actually DECREASES male lifespan, perhaps by as much as 20 years. For example, from a very well controlled study on the lifespans of Korean eunichs: http://www.sciencedirect.com/s...: "The average lifespan of eunuchs was 70.0 ± 1.76 years, which was 14.4–19.1 years longer than the lifespan of non-castrated men of similar socio-economic status. Our study supports the idea that male sex hormones decrease the lifespan of men." I entirely support having the choice to take testosterone, for whatever reason one would like. I have a friend who's life has been quite improved by testosterone treatment, in fact. BUT taking T to help with unspecific effects of aging is a dangerous experiment and fad and people should be aware that there are likely to be some very serious and unforeseen consequences. I managed to talk my aging father out of this treatment, and as a consequence I just may be able to enjoy his company for years to come. Any doctor who suggests taking T to prolong lifespan is either critically misinformed or displaying severe lack of judgement, imo. And the author of that paper, who keeps referring to T as a magic wand? He is an idiot. I'm not a medical doctor but I am a PhD and I have done studies on the effects of sex hormones on animals. It's not clear why testosterone might decrease the lifespan of men, but one likely candidate is the fact that testosterone clearly decreases immune system function.

    10. Re:Article did not discuss downsides by gtall · · Score: 1

      T is, to quote a colorful phrase I read from a study on T, is gasoline to a prostate cancer. In fact, one of the treatments is chemical castration under the understanding that for the right people, it will delay the onset of death by that cancer until something else gets you instead. My father took those treatments from sometime in his 70s until he died of old age at 91...his prostrate cancer was held in check and was not the cause of his existence failure.

    11. Re:Article did not discuss downsides by Anonymous Coward · · Score: 0

      Testosterone also causes baldness

    12. Re:Article did not discuss downsides by Anonymous Coward · · Score: 0

      Or not being banned from sports competitions and then having to appear before congress.

    13. Re:Article did not discuss downsides by jafac · · Score: 1

      A lot of older guys are not particularly worried about the fertility bit.

      Prostate enlargement, on the other hand. . .

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    14. Re:Article did not discuss downsides by LynnwoodRooster · · Score: 2, Funny

      The longer lives of the eunuchs wasn't from lower T - it was from not having 50 years of nagging wives...

      --
      Browsing at +1 - no ACs, I ignore their posts. So refreshing!
    15. Re: Article did not discuss downsides by Anonymous Coward · · Score: 0

      There's more to it than that.

    16. Re:Article did not discuss downsides by nbritton · · Score: 1

      Actually, contrary to common believe, low testosterone is associated with aggression and high testosterone with reduced aggression.

    17. Re:Article did not discuss downsides by iMactheKnife · · Score: 1

      Contrary to popular opinion, correct dosage of testosterone does not enlarge the prostate or decrease fertility. However, if you have prostate cancer with cells that have testosterone binding, you will be feeding the cancer cells.

  9. About time by PvtVoid · · Score: 0

    I for one welcome our testosterone-enhanced geriatric libertarian overlords!

  10. in other words, manufactured ailment. by nimbius · · Score: 4, Insightful

    "client-centered libertarian medicine." is how assholes pronounce the words "snake oil" and It lives on the shelf with things like homeopathic remedies and juice cleansing. Testosterone, multi-inhaler asthma treatments, statin deficiency,and Circadian Dysrhythmia are all part of pharmaceutical corporations nose dive into profit with the concept of fear, forever and faith. Fear the disease, remember that once you have it you must always consume the product to relieve it, and finally never doubt your trust or faith in the product despite overwhelming evidence it may even be detrimental to your health.

    people become old as a part of human life. Testosterone does not radically alter that condition because becoming old is not a problem but a feature of life itself. In the United states as we inch inexorably closer to single payer healthcare its becoming increasingly evident to medical corporations that an alternate revenue stream will need to be secured. As an example, cigarette manufacturers diversified into food and alcohol; they realize relatively little revenue from cancer sticks at all.

    --
    Good people go to bed earlier.
    1. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 2, Insightful

      I do think this sounds a bit like snake oil, but I also agree that medicine needs to be deregulated, and treated like taxes: you can make your own decisions, but might also want an expert. These people are making their own decisions--so what if it's misguided? What do you care? And as the article states--why not collect data and see what's going on? Why rely on the FDA to make that evaluation? Because the FDA is never wrong?

      The problem is that, for every one of these examples, there's many many more of people trying to get basic medicines that they either can't get, or become costly to get (in terms of time or money, or both, because they're the same), because of overregulation. Do you really need a doctor or PA or NP for every prescription you get? No--I suspect that many Slashdot readers could make those decisions themselves, either when they start taking a med, or after an initial consultation, or could get meds from other providers. Has the war on drugs been successful? I think not.

      As I've grown older, I've come more and more to the opinion that if the government is trying to protect you from yourself, it's probably doing something it shouldn't be doing.

      I should go in for medical care because I need help, not because the government tells me I'm not in the capacity to make that decision for myself.

      Why do I really care what snake oil people take? If it makes them happy or fulfilled, let them do it. It's better than about a million other things they could be doing.

    2. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 0

      More libertarian stupiness, even when showed the consequences, they refuse to understand.

    3. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 0

      "Why rely on the FDA to make that evaluation?" It is a problem of motivation not implementation. The organization that makes the decisions on the safety of my medicine should not have profit as primary motive because I can't outpay big pharma.

    4. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 1

      Unlike taxes, where the feds will simply audit you and take care of the delta, medicine misused can kill you. And unlike operating a car, which is something everybody can do with a little practice, medicine requires a major investment in understanding the mechanism of action, proper dose, etc, that the scientists can't seem to get right some of the time.

      You also don't understand why medicines cost so much. It's not overregulation. It's research and development costs to find something that is both 1) new and 2) functional.

      You seem to think that people don't need a doctor or NP for every prescription. People would take antibiotics for anything, including the common cold, which damages our ability to fight diseases where these drugs actually work. Some may be smart about it and take it for a bacterial infection. Do you take broad spectrum? Cephalosporins? Is your infection gram negative or gram positive?

      There's a damn good reason we let government and doctors control who gets these drugs. They're powerful and harmful. These aren't harmless little recreational drugs that make you feel better and this isn't a discussion about the war on drugs. I'm damn happy people so grossly misinformed as yourself aren't in positions to be making these decisions.

    5. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 1

      No, modern medicines cost so much because drug companies strive to find something that is both 1) marketable and 2) patentable.

      New doesn't matter if they can twist patent law, and functional never really mattered as much as the perception of function.

      I wish we'd put more research into anti aging and less into cosmetic crap, and a medical community actually concerned with medicine would have different priorities.

    6. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 0

      recreational drugs aren't harmless either

    7. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 0

      medicine misused can kill you

      Why is it your business if I decide to do something stupid and kill myself? Why would you want to stop me from attempting Everest in a couple of years, that has a rather high mortality rate also.

    8. Re:in other words, manufactured ailment. by Anonymous Coward · · Score: 0

      I can't speak towards the other conditions, but Circadian Dysrhythmia is just a medical term used for jet lag. If you don't think jet lag is real then your world view is highly distorted. Fly through 8 timezones going from 10pm to 2pm. Now it's 5pm where you are and you're tired because your body expects it to be 1am now. That's jet lag. How did you delude yourself into thinking that isn't real?

      Most people can move their circadian rhythms (body clocks) forwards/backwards a few hours each day. Some can do it easier than others and some can't do it at all (those with N24 and DSPS). Jet lag is technically a medical condition since your body is out of sync, but it's not a major one. You can power through it (like sport players power through concussions), or your can buy generic melatonin (the hormone your body uses to regulate your circadian rhythm), or your can play with light levels by wearing a sleeping mask that covers your eyes (to fall asleep earlier) or stay around some bright lights for a little while (to stay awake longer). There's no grand conspiracy here.

    9. Re:in other words, manufactured ailment. by TapeCutter · · Score: 1

      It's none of my business if you want to self medicate with whatever drug you fancy, that's "freedom". An unqualified but charismatic quack taking advantage of desperately ill people for personal gain is not "freedom", it's fraud.

      By definition alternative medicine has either been proved not to work, or not proved to work. Do you know what they call alternative medicine that has been proved to work? Medicine" - Tim Minchin.

      --
      And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
    10. Re:in other words, manufactured ailment. by Baki · · Score: 1

      Sometimes there are benefits and risks at the same time. The suppliers seek big profits and will always emphasise the benefits. It is not that black and white, and therefore not so easy to get a fraud judgement when suppliers skew the opinion of the people through large marketing budgets. The profits easily pay for a lot of influence.

      Sometimes politics has to regulate, and especially neutralize the unwanted pressure from commerce. There are various means, such as diminishing the lobby influence over politicians, to having a strong public television system to counteract skewed information from commercial parties.

  11. Sanity check... by Anonymous Coward · · Score: 0

    This doesn't sound sane to me. Statistically, women live longer then men, so the solution to making men live longer is to increase their testosterone, presumably so they can match the women.

    Where the heck do these "scientists" live, anyhow?!?

    1. Re:Sanity check... by tnk1 · · Score: 1

      I'm not sure that the reason that women live longer is specifically due to their hormones (or lack of male hormones). There are still considerably different social expectations between the sexes in terms of risk taking and aggression even putting aside natural inclinations. That alone might account for the difference.

      Not to mention that women suffer from a drop in estrogen production at menopause, so they likely have a deficiency of that hormone when they are old enough for it to make a difference.

      It may be a lifetime of a demeanor influenced by high levels of estrogen that is responsible for living longer, but I don't think that testosterone is necessarily contraindicated, especially since men start to produce less of that, as well, as they get older. It may simply be learning to control the aggression or other effects of that hormone in practice.

    2. Re:Sanity check... by king+neckbeard · · Score: 1

      You do realize that men and women have significant differences in their biology, right? What may be ideal for women's health may not be ideal for men's health. Also, the goal doesn't appear to be extending lifespan so much as improving quality of life.

      --
      This is my signature. There are many like it, but this one is mine.
    3. Re:Sanity check... by Anonymous Coward · · Score: 0

      Sexist! We're all the sameeeeeee

    4. Re:Sanity check... by Anonymous Coward · · Score: 0

      No, we are not.

      We are equal [socially] , but different [biology, behavior]. And a good thing this is...

  12. Lift by kilfarsnar · · Score: 5, Insightful

    If you lift weights you can boost your testosterone naturally. And you'll get other benefits like more strength, increased bone density and better balance. You don't have to be Jack LaLanne (though he provided an excellent example). You just need to put your body under stress for 30 - 60 minutes 2 - 3 times a week; in a way that is safe for one's age, obviously.

    Regular exercise and a healthy diet can go a long way towards staying healthy and living longer. But we knew that already and still many of us do not do it. There's still the testosterone shot, I guess...

    --
    "What the American public doesn't know is what makes them the American public." -Ray Zalinsky (Tommy Boy)
    1. Re:Lift by Joey+Vegetables · · Score: 2

      I agree, but a man will benefit from those activities even more if his T starts out being near, or perhaps even slighly above, normal levels, with "normal" being defined not as the average today, which we know is much lower than in the past for various reasons, but the average from 30 years ago. I am not sure this is a bad thing as long as there is competent medical supervision. It's not for everyone; as others have pointed out, it can worsen heart problems, hypertension, aggression, etc. especially if done to excess. But many Americans are low due to medications, chemicals, age, etc., in addition to still-as-yet-unproven reasons. Proper diet, exercise, *and* supplementation may turn out to be the right solution for many people.

    2. Re:Lift by hondo77 · · Score: 1

      ...which we know is much lower than in the past for various reasons...

      {{cite}}

      --
      I live ze unknown. I love ze unknown. I am ze unknown.
    3. Re:Lift by Anonymous Coward · · Score: 2, Informative

      Unfortunately, most people do not understand what it means to have low Testosterone. I suffer from low T and am familiar with this subject:

      1. Having low T means you have an organ somewhere not working. Primary: Testes. Secondary: Pituitary. Tertiary: Stress.
      2. Herbal supplements and working out do not raise Testosterone if you suffer from Primary/Secondary failure, because you cannot produce adequate amounts in the first place.
      3. Testosterone is not steroids. It is bio identical hormone. As someone pointed out in a previous response, if you were a body builder, you would be taking a steroid. Something way more potent.
      4. TRT, testosterone replacement therapy, simply puts a man WITHIN NORMAL RANGE of other men. Scales vary by lab, but a popular one is 300-1000. As a 35 year old man, comparing myself with the limited data available (fairly new science), i scored a 220. I'm suppose to be 400-600 atleast for my age. A man on TRT will simply receive (assuming he doesn't abuse it) will simply be dosed so that his TOTAL T falls within the avg range.

      Testosterone WORKS. Having only taken t-cypionate, i can tell you the difference for someone who suffers from low T (fatigue, memory loss, no libido, no morning erections, no real muscle gains in the gym) is night and day. Most guys just assume they are stressed out or unhappy when they suffer from these problems, like i myself did, but a body building friend of mine swore to me up and down that i had to have low T and i should get blood work done. 1 year after hearing him tell me the same thing, i went and got checked.... and he was right. I was below the minimum amount of acceptable testosterone. Not believing this, i got tested 3---- more times, at different clinics. I failed the test every time. So, i decided to 1 month of Test. I can tell you, that i use to 'feel normal' minus the libido, terrible sleep, and forgetfulness. By my 3rd day on T, i woke up with an erection which would have made my father proud, i actually wanted* to sleep with my girlfriend, and i was easily pushing more weight than i had been capable of in a long time. Testosterone is, bar none, THE CURRENCY in a man's body.

      Having been on both sides, i now REMEMBER what normal is. It's NOT normal to not want your girlfriend. Its NOT normal to have weak erections or no morning wood (when your 35), and its NOT normal to have crappy sleep and wake up every few hours. Increasing my T to 'regular' levels comparable to other 35 year olds SOLVED all of these issues for the duration that i was on it. So please, if you're like me, and really have a need for it.... PLEASE, ignore all the crap you hear about it, and try it.

    4. Re:Lift by delt0r · · Score: 1

      Funny thing is there is very little evidence that testosterone helps at all in normal men.

      --
      If information wants to be free, why does my internet connection cost so much?
    5. Re:Lift by Anonymous Coward · · Score: 0

      I raise you 1 more set of anecdotal evidence.

      I have unusual testis. So lower testosterone was not a surprise. But it was just low, as in about the same as you and the same age. Not all that far out of normal range. But i was having performance problems (not libido problems). Testosterone made absolutely no difference at all to anything. I took it for 6 months. Now little blue pills... sheesh i can go all day long! Sure they are $10 a pop. But pop them i do.

  13. Not entirely untenable by ItsJustAPseudonym · · Score: 2

    ...it is a paradox that has put regulators in an untenable position.

    Maybe not entirely. Here's a recent article about fake supplements: http://www.washingtonpost.com/...

    Regulation, apparently, has its part to play.

    1. Re:Not entirely untenable by Bonzoli · · Score: 1

      The idea makes me think of BeekCake 9000.

    2. Re:Not entirely untenable by phantomfive · · Score: 1

      Yeah, I'm having trouble seeing what the paradox is. If a doctor prescribes it, then great! If it fits the requirements for OTC, then great! Standard procedure, no paradox except in that guy's mind.

      --
      "First they came for the slanderers and i said nothing."
  14. It's Misogyny by Anonymous Coward · · Score: 0, Troll

    The "solution" is staring regulators in the face. Testosterone is a male drug. Men oppress women. Therefore testosterone is misogynist.

    Just look at these side effects: "productivity, physical attractiveness, and sexual viability"
    - Productivity: Objective metrics promote meritocracy, which is sexist.
    - Attractiveness: A form of able-ism and objectification. Demeans the rights of heterosexual lesbians to promote trans-gender body satifaction, thus perpetuating opression.
    - Sexual viability: A euphemism for the promotion of Rape.

    Testosterone supplements support Rape culture. There are a toll used by MRAs and PUAs to further the oppression and exclusion of women in the workplace and in retirement. We need to regulate the distribution of these harmful drugs and shame those who openly promote their use. Society needs to understand that testosterone culture is toxic and has a real impact on our society.

    1. Re:It's Misogyny by Anonymous Coward · · Score: 0

      lol

    2. Re:It's Misogyny by rogoshen1 · · Score: 1

      why did i post before reading this, and thus lose the ability to mod :(

  15. This sounds pretty familiar... by Anonymous Coward · · Score: 0

    :%s/HGH/testosterone/g

  16. Do the Division by rjstegbauer · · Score: 1

    From the article:
      "In 2013, 14,000 kilograms of testosterone were sold in the United States. That might not sound like much, but a typical adult male has just 0.000000035 kilograms of testosterone floating around in his bloodstream."

    That means that enough testosterone was produced to increase the amount of testosterone in *every* man in the world by 200 times. WOW! I wonder what the effects are of a 1000x increase...that some men must be getting?

    1. Re:Do the Division by Russ1642 · · Score: 1

      Just a guess but the article you're referencing probably has the weight wrong. Maybe they measured the weight of liquid or pills rather than actual testosterone. It just seems so far out to lunch it has to be wrong.

    2. Re:Do the Division by Anonymous Coward · · Score: 3, Informative

      No, it absolutely does not mean that. What you said would have made sense if 14,000 kilograms were all used in one instant not throughout the whole year.

      The typical blood content cannot be used to establish dosage without the half life, which in this case is only 2-4 hours. So you would need quite a few doses of 0.000000035 kg per day just to keep the level around that value. In practice, typical dosages that lead to normal blood levels are on the order of 100-200mg per week. With that in mind 14,000kg equates to year-long treatments for 1.5-3 million men.

    3. Re:Do the Division by rjstegbauer · · Score: 1

      The "article" was TFA...which somehow I actually read.

    4. Re:Do the Division by rjstegbauer · · Score: 1

      Oppps!

      I'm good enough at math but not so much at biology!

  17. Side effects may include death by John+Newman · · Score: 3, Interesting

    Testosterone supplementation in men with low T levels appears to have the unfortunate side effect of death.

    There is a growing literature on the potential dangers of testosterone supplementation. Not enough yet to say it's as clearly a bad idea as female HRT, but for sure it isn't something men should run out and do without a careful and personalized discussion with a knowledgeable (actual) doctor.

    In general I think it's safe to say that the "take extra of the hormones that go down with age in some people" theory of fighting aging is pretty thoroughly discredited by now. Thyroid hormone, growth hormone, testosterone, estrogen, etc. - the science is clear this is not how you fight aging. In general, more likely to hasten death than prevent it.

    1. Re:Side effects may include death by Joey+Vegetables · · Score: 2

      This is well understood, and means that testosterone therapy is contraindicated in people with, predisposed to, or having a family history of these problems. That would include me. It also means it may be risky for others. I am considering it anyway, for the simple reason that I'd rather be maximally healthy for 20 more years than to live 40 in my current condition, which is influenced by low testosterone (it is not absurdly low, just a little, but still affects my life in countless ways, nearly all of them negative).

    2. Re:Side effects may include death by judoguy · · Score: 2

      Not enough yet to say it's as clearly a bad idea as female HRT, but for sure it isn't something men should run out and do without a careful and personalized discussion with a knowledgeable (actual) doctor.

      Even endocrinologists, unfortunately, are not immune to cant and insurance industry pressure.

      Too many of them just run insurance driven diabetes shops and ignore actual science in adherence to "conventional practice", i.e., not what works, but what is defensible in court.

      --
      Peace is easy to achieve, just surrender. Liberty is much harder get/keep.
    3. Re:Side effects may include death by Anonymous Coward · · Score: 0

      Oh ffs. "Testosterone supplementation" is not the same as testosterone hormonal therapy.

  18. testosterone problems by Anonymous Coward · · Score: 4, Insightful

    As a physician, I have seen the growth of the testosterone industry over the past decade. This has been pushed by direct to consumer advertising by big Pharma, which fails to adequately inform the target population of the significant risks. Co-opted endocrinologists have been paid to create a new syndrome called "andropause" which can be treated with testosterone. We learned the risks of estrogen in post menopausal women only after many years, and we now are set to repeat the same story with cardiovascular disease, prostate problems, and stroke in men. Why can't we just age gracefully?

    http://www.drugwatch.com/testosterone/heart-attack/
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901445/

    1. Re:testosterone problems by Anonymous Coward · · Score: 0

      Your comment made me think of a quote from "The Big Bang Theory": "Last month my company both invented and cured restless eye syndrome."

      I just knew that show isn't fiction!!

      8^)

    2. Re:testosterone problems by blue9steel · · Score: 2

      Why can't we just age gracefully?

      Why would we want that? Natural != Good I happen to like vaccinations, antibiotics, pain killers and other marvels of modern medicine, why don't you?

    3. Re:testosterone problems by Anonymous Coward · · Score: 0

      GP didn't use the word "natural" at all.

    4. Re:testosterone problems by yabos · · Score: 1

      Most old people can barely get out of a chair. I don't want to be like that if it can be avoided. That's why I lift and have more than average muscle mass. The more you have when you're younger, the more you will have when you're older. Higher test will just allow you to keep more of it later in life.

    5. Re:testosterone problems by Anonymous Coward · · Score: 0

      Re: "Why can't we just age gracefully?"

      My understanding is that the Baby Boom generation doesn't accept any of the 'inevitabilities' of life.

  19. I like dexedrine. by pigiron · · Score: 1

    It gives me warm and fuzzies plus I can concentrate like a demon.

  20. change your diet and exercise instead by NostalgiaForInfinity · · Score: 4, Insightful

    Low testosterone, aging, and loss of lean muscle mass, fat gain, obesity, diabetes, heart disease, low libido all correlate. Because testosterone supplementation improves some of these problems somewhat, people have concluded that they might be caused by low testosterone. But they are clearly caused simply by bad diet and lack of exercise, and you're likely going to improve your overall health much more by exercising and eating better. Exercise and improvements in diet will also naturally increase your testosterone levels.

    Once you start taking testosterone, you usually end up dependent on it for life. That means not just applying it every day, it means more frequent checkups, monitoring for side effects, and pretty tough questions when you start getting prostate problems and cancer (which you will, sooner or later).

    Trying to fix what are just bad lifestyle choices in most men (lack of exercise, too much sitting, bad diet) with medicine (statins, testosterone, etc.) also puts an enormous strain on our medical system and is one of the reasons the US spends so much money on health care: the cost of testosterone replacement is usually several hundred dollars a month for the drug alone, plus even more money for the extra monitoring and tests. Insurance may currently cover that, but don't bet on it in the future. And even if it covers it, you still end up with co-pays, frequent trips to the doctor, and potential complications and additional drugs to deal with side effects.

    (Of course, some small percentage of men really do have abnormally low or absent testosterone due to actual disease, and for those, supplementation makes sense.)

    1. Re:change your diet and exercise instead by IcyWolfy · · Score: 1

      Testosterone injections, rather than Androgel is significantly cheaper. $25 for 10mL(200mg/mL) without insurance.
      For me, that's $25 for a 3 month supply. (supposed to chuck the rest of the vial at that point, even though it's still not empty)
      The largest expense is the lab work, but paying cash out of pocket comes out to $350 / year;

      So, the cost for HRT with no insurance, is $450 annually.
      That's less than $25/month.

      And insurance will cover my visit to the Endocrinologist, but they won't cover the actual Rx or the Labs they see no value in.

      But, with the shots, you have to
      a) change your diet to actually get the 30g of soluable fibre a day (to control higher cholesterol)
      b) perform a lot more cardio exercise (to maintain CV health)
      c) preferably donate blood (to rid of excess red blood cells, keep blood pressure in check)

      Not a free ride, but it does help significantly to the daily quality of living.

    2. Re:change your diet and exercise instead by wisnoskij · · Score: 1

      Once you start taking testosterone, you usually end up dependent on it for life. That means not just applying it every day, it means more frequent checkups, monitoring for side effects ...

      So I guess now we can now understand why the medical community has taken to it in such a big way. It is like there perfect drug, from a pusher standpoint.

      But, I guess, it can lead to a cyclical relationship on its own, without the supplement. Theoretically, at least, the boost of testosterone could cause the taker to get off their ass and start with the health stuff; And start producing their own.

      --
      Troll is not a replacement for I disagree.
    3. Re:change your diet and exercise instead by NostalgiaForInfinity · · Score: 1

      That's why I said "usually". You can lower costs that way, but the majority of men will not want to inject themselves. Also, the majority of men will probably not make the other changes you made.

      Did you try the lifestyle changes before replacement therapy? I had low-T and my doctors wanted to put me on supplementation (my health plan even covers it). I tried it briefly and it made me feel better, but I stopped and just changed diet and exercised, and it normalized on its own over time.

    4. Re: change your diet and exercise instead by Anonymous Coward · · Score: 0

      I get testosterone injections every 3 weeks due to pain medication. I suffer from chronic pain due to failed back surgery. Plus I have 2 more bulging discs causing additional pain. I was constantly tired and my libido was low. The injections have made an improvement to my life both in and out of the bedroom. I'm very thankful for injections because changing my diet wasn't enough.

    5. Re:change your diet and exercise instead by Anonymous Coward · · Score: 0

      Well, for me, the prospect of becoming dependent on a drug for life was what caused me to get off my ass and start with the health stuff, and it normalized my testosterone. Hence my recommendation: before you start testosterone replacement, get down to a low-normal weight, reduce stress, eat a healthy diet, and exercise moderately; your testosterone will probably normalize on its own, and you'll get the health benefits of both being in better shape and better hormonal levels.

    6. Re:change your diet and exercise instead by wlowe84 · · Score: 1

      Where do you live that you only pay $25 for 10mL(200mg/mL). That's about what I pay for 1mL(200mg/mL) (in the U.S.), and my insurance won't pay any of it.

    7. Re: change your diet and exercise instead by Anonymous Coward · · Score: 0

      That sounds entirely reasonable. TFA is about "fighting aging", though, not actually treating disease as in your case.

  21. 60 minutes by fxsoap · · Score: 1, Interesting

    Wasn't there a 60 minute special on this exact thing within the last 5 years? Showed that you increase chances of cell dividing incorrectly and thus can produce cancer? (specifically, prostate cancer)

  22. Take this crap down by Anonymous Coward · · Score: 1

    This baloney doesn't belong on the front page of slashdot anymore than homeopathic anecdote or anti-vaccine propaganda. There will always be some asshole who will sell you something useless to not fix a perceive problem you think you have. We shouldn't give these charlatans a megaphone to spout their sales pitch.

    1. Re:Take this crap down by Yergle143 · · Score: 1

      This screed is also very non scientific and non technical. You are right, this article reads like slashvertisement.

  23. Probably not a bad idea by Anonymous Coward · · Score: 0

    Considering the amount of female hormone facimiles in our foods due to wrapping everything in BPA-laden plastics.

  24. Algebra by Anonymous Coward · · Score: 0

    A little Algebra... 14.000.000 / 0.000000035 = 4 * 10^14 bloodstream doses. Enough for roughly 110 thousand times the population of the world (men only). I think somebody might be exaggerating, here. Or the testosterone is used for various other products

    1. Re:Algebra by IcyWolfy · · Score: 1

      14,000kg = 14,000,000g = 14,000,000,000 mg
      HRT dose ranges from 100-200mg/wk for legitimate use. (500-1000mg/wk for recreational)
      14,000kg / (100mg/wk * 52wk)
      = 2,692,307 people at 100mg/wk for 1 year
      = 1,346,153 people at 200mg/wk for 1 year
      = 673,076 people at 400mg/wk for 1 year

      First doctor was lazy in Rx writing and just wrote 1mL 2x/wk (which renders a Rx for 400mg/wk)
      Even though verbal instructions were 1mL every 5 days (250mg/wk)

  25. Fight Aging? by MagickalMyst · · Score: 1

    Why do humans feel the need to fight every issue that arises?

    Can't we simply say that we have a problem that requires a solution?

    We fight hunger, fight poverty, fight disease, fight aging...

    Perhaps if we, as a society, took a more harmonious attitude towards our worldly problems then perhaps we could finally stop "fighting" our problems and actually come up with solutions for them.

    Attitude is everything.

    --
    Political correctness is really just herd psychology pushed by insecure people who desperately seek social conformity.
    1. Re:Fight Aging? by BarbaraHudson · · Score: 2

      Why do humans feel the need to fight every issue that arises?

      Too much testosterone?

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
  26. Cause of low T in aging males. by anwyn · · Score: 1

    In most males with low T is T being regulated down, can the equipment just not produce enough T. In other words is my house cold because the thermostat is set too low, or is the furnace too small?

  27. I don't get it... by Anonymous Coward · · Score: 0

    Life is finite for a reason. Why not just age gracefully (barring health conditions needing treatment)?

    I dislike artificial anything. If you go bald, let it happen. Same for testosterone and anything else. Better living through science is a myth. We were healthier back 50 years ago when we were not poisoning our food, coloring our hair, drinking heinously bad-for-you sugar water/caffeine concoctions. Diabetes is at an all time high, our food is poison, we don't work out. Is it any wonder we are all fat and unhealthy? America is between 35-45% overweight in the adult population. Children are creeping up there at a current 25-30%.

    No thank you, I will age gracefully if God allows it and stay all natural. Society, sadly, preaches that men are sexual conquistadors and if a man is not a virile guy looking like he's ready to fight the battle of Thermopylae, he's a loser who doesn't deserve to sire children unless he shacks up with a fat redneck chick. We are our own worst enemy.

    1. Re:I don't get it... by bigwheel · · Score: 1

      Devil's advocate here. Life expectancy has steadily increased despite all that bad stuff. Both in the US http://demog.berkeley.edu/~and... and worldwide http://en.wikipedia.org/wiki/L...

      If you want to age gracefully and not take steps to repair age-related problems, then go for it.

      I know that life is finite. But all things considered, I prefer to postpone death, and make the interim time as pleasant as possible. That's why I do things like exercise, eat properly, and go to the dentist. And if there is a fix to an age-related illness or problem, then I'm all for it. The hard part is figuring out what is real, and understanding the trade-offs.

    2. Re:I don't get it... by king+neckbeard · · Score: 1

      The mere concept of 'artificial' is a fabrication, and we have a number of ways that our lives have objectively improved. Also, there was a lot of awful stuff 50 years ago, including leaded fuel.

      --
      This is my signature. There are many like it, but this one is mine.
  28. Tipping the balance by digsbo · · Score: 1

    This kind of thing, in a small but significant way, starts to tip the social balance further in favor of males who are wealthy enough/risk tolerant enough to take a chance on this kind of thing to dominate against younger males.

    On the side of the wealthier males, it could tend to change certain workplace dynamics. Not sure what exactly that would do, but without economic growth, it could lead to slightly more workplace conflict.

    On the risk tolerant side, I see a risk of widespread increases in antisocial behavior as young, aggressive males amp-up their natural tendencies. Violence and crime are likely results. Given that we're already past the societal stage where we kill off lower-class males in wars of attrition, we're going to be facing an unprecedented dynamic with larger numbers of aggressive males than society is accustomed to.

    1. Re:Tipping the balance by wisnoskij · · Score: 1

      I don't see it. The rich successful people already have decent T, T supplements are for the ones too pathetic to accomplish anything to begin with. It is not like .001 gram of T will cost you thousands of dollars. And since, at least, natural T leads to reduced violence and crime, I see no reason to believe that unnatural T would do anything but make people even less violent.

      --
      Troll is not a replacement for I disagree.
    2. Re:Tipping the balance by king+neckbeard · · Score: 1

      Where is the evidence that natural testosterone leads to reduced violence and crime? Males in the teens to twenties range make up basically all violent crime. Also, a cursory glance seems to indicate that eunuchs don't commit crimes very often despite the anger that castration would cause.

      --
      This is my signature. There are many like it, but this one is mine.
    3. Re:Tipping the balance by wisnoskij · · Score: 1

      Well the crime is a personal extrapolation from the more recent studies that have found that individuals with higher T were statistically correlated with being more generous, having more friends, and being more friendly.
      In fact almost all violent crimes are committed by Black males who in fact have even higher T statistically than males in general. But males and black males specifically do not commit crimes because of high T, we know this because of a series of studies that link it to higher cooperation, friendliness, and generosity.

      That is because low T causes depression, and depressed people, while often angry, are to lazy to do anything. I have yet to see any decent studies that actually link anger, or antisocial behavior, to T. And quite a few of the more recent ones have found both this lack of a correlation and a correlation with T and friendliness, ect. T causing violent crimes is just a myth kept alive out of bigotry, because they want a science-y term to use to explain why these men are all so violent and inferior to them. These same people probably want to say that it decreases intelligence as well.

      --
      Troll is not a replacement for I disagree.
  29. Dangerously wrong - snake oil by bradley13 · · Score: 1, Interesting

    Somebody is selling snake oil again. Testosterone may have subjectively beneficial short-term effects (virility, muscle tone, etc), but all current evidence is that it shortens your lifespan.

    Studies of eunuchs have shown that they live substantially longer than non-castrated men. That's just one link; anyone with a bit of Google-fu will find others. For example, higher levels of testosterone are thought to be a reason that men have shorter lifespans than women.

    --
    Enjoy life! This is not a dress rehearsal.
    1. Re:Dangerously wrong - snake oil by Anonymous Coward · · Score: 0

      You're seriously arguing that men should prefer to live with a lower quality of life just prolong their lifespan? What's the fucking point?

    2. Re:Dangerously wrong - snake oil by Anonymous Coward · · Score: 0

      Well if your into fucking i wouldn't recommend blue pills or the equivalent. They work a lot better than testosterone, and lets be clear. Studies have not really shown the benefits that are often claimed.

  30. Re: by Anonymous Coward · · Score: 1

    Please elaborate on the "clear dangers" of marijuana...

  31. There are a Lot better Ways to Up Your T by wisnoskij · · Score: 0

    but sadly all of them involve at least a little moving, so I guess everyone will have to continue taking supplements.

    --
    Troll is not a replacement for I disagree.
  32. Re: by hawkinspeter · · Score: 4, Funny

    You can burn your fingers if you're not very good with a lighter.

    --
    You're a temporary arrangement of matter sliding towards oblivion in a cold, uncaring universe
  33. Narrowing that down, if 10% become mass murderers by raymorris · · Score: 2

    > In such cases the government should step in, if:
    > - The number of problem cases far outweighs the number of normally functioning users, and

    I wonder if we can make this a bit more specific and clear. You said "the number of problem cases", but I wonder if you meant "the direct and indirect effects of problem cases". Here's why I say that:

    Suppose that smoking Z has limited negative effects on 90% of users. Perhaps most just get lazy and unmotivated. However, 10% of users commit mass murder. Going strictly by the words you wrote, substance Z shouldn't be regulated - most users don't become dangerous. The people who are not dangerous ARE however killed by the 10% who go postal. That would be a problem.

  34. Re: by Immerman · · Score: 2, Informative

    There have been several studies now that suggest that marijuana use, particularly heavy use, among minors (prior to early twenties, while the brain is still developing ) cause a drop in intelligence and significant structural brain changes of unknown impact.

    Still wouldn't be my go-to drug to reference for "clear dangers" - the only clear dangers that spring to mind are are those shared by alcohol - the perceived safety, combined the proclivity for doing stupid things under the influence. Granted alcohol is a lot more likely to get you into life-threatening situations, but some puritan parents might consider getting laid to be similarly dangerous to their precious indoctrinated babies.

    Beyond that there's always the old saw the "Marijuana is hazardous to your health - it can cause your ass to be thrown in jail" - which is in fact probably by far the greatest danger of the drug, and a very real danger at that.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  35. testosterone problems by Anonymous Coward · · Score: 0

    If aging gracefully means breaking down like most men I see I their 60;s and 70's I'll take ungracefully aging. how much better is 20 years of shuffling vs 15 years of good health at the end of your life

  36. Bull by Anonymous Coward · · Score: 0

    Two words "clinical trials", if no "clinical trials" then no sale.

  37. Fluoride and Girly Men by Trihalo42 · · Score: 1

    http://www.ncbi.nlm.nih.gov/pu... [Effect of fluoride on human hypothalamus-hypophysis-testis axis hormones].
    (PubMed)

    RESULTS:
    "The concentrations of fluoride in the water, food and soil of the fluoride polluted district were significantly higher than those of control district (P 0.05). The serum level of LH in men of fluoride polluted district was significantly higher than that of control group (P 0.05), and the serum level of T in men of fluoride polluted district was significantly less than that of control group (P 0.05). "

  38. Re:Oh shit! by Applehu+Akbar · · Score: 1

    "You wanna piece of me, sonny! "

    Around here we call this senior discount Wednesday at Kroger.

  39. Testosterone Gap? by DarthVain · · Score: 1

    ...have you never wondered why I drink only distilled water, or rainwater, and only pure-grain alcohol?

    1. Re:Testosterone Gap? by Anonymous Coward · · Score: 0

      shame that nobody got the joke enough to rate you a 5..... carry on Mandrake

  40. It is time to change the FDA and drug law. by jd.schmidt · · Score: 1

    True story, well if you can believe my dentist, but she seems very rational person. She said her brother had started selling a wrist watch that was used to combat ADD, basically is would vibrate and give an "atta boy" message when the child got off track, it was remote controlled by the teacher FYI. It was about as intrusive as a digimon watch. So he started selling them, but eventually got a cease and desist letter from the FDA for selling an untested medical device. When he later spoke with an FDA insider, he was supposedly told drug companies got wind of the device and turned him in, along with applying a little influence, to get him shut down. I think the day may have come to limit the FDA to verifying the purity of the drug or substance you are buying, but not make decisions on it's proper use. Maybe something closer to a medical research wiki with verification of information sources (so companies couldn't falsely claim results). Maybe the FDA could monitor the checks and balances of such a system or something. Over all the system would be less like "buy my anti balding pill" and more like research has shown chemical X reverses baldness, and the following companies sell chemical X and compete on prices. Drugs would become de-facto generics in most cases.

    1. Re:It is time to change the FDA and drug law. by WorBlux · · Score: 1

      Yes seperating the approval and research process from the manufacturing process would to a great deal to decrease medical costs, but could have a negative impact on research if it wasn't done carefully.

    2. Re:It is time to change the FDA and drug law. by jd.schmidt · · Score: 1

      Maybe, maybe not. First remember how much basic research is done by universities, further much the same thing has been said about open source software. Remember I am not proposing the elimination of for profit drug research companies, but rather simply opening the door for more open source type avenues also.

  41. Yoga by Anonymous Coward · · Score: 0

    Studies have show yoga increases testosterone too. I'm not sure why but it does. It's also one idea why more women do yoga then men. Women have lower testosterone levels, so the slight increase is more noticeable to them.

  42. So thankful for testosterone supplements.. by Anonymous Coward · · Score: 0
    Given that I'm a cancer survivor, after two separate encounters with testicular cancer, I'm really glad that I can get testosterone supplements at all. I longer can produce enough myself, so I'm on fortnightly injection of 250mg of testosterone entanthate; with 8 years of bloodwork to see where my levels are at, I'm able to tell you within ~5 nmol/ml of my level by how I am feeling. I am unlucky again in that I metabolise testosterone significantly faster than the norm, and I get topup gels to apply towards the end of my fortnight.

    My levels before the operations and chemo were always higher than the average, but being at the average made me feel like crap and people around me were able to tell me when the levels were low as I'd become a lot more bitchy and cutting in my interactions with people. It's funny, very high levels do not make me angry, just extremely horny to the point where I can't hold a conversation with someone because a nice pair of boobs walked past. That particular episode is what taught me not to exercise within a few hours of getting that injection! At least I now have the ability to maintain these normal-for-me testosterone levels as I age, and to maintain the ability to keep doing what I currently do sports-wise, and not worry so much about the degenerative crappiness that I know only too well from overly low testosterone levels.

  43. Such a sad use of SI/metric by Ydna · · Score: 1

    "0.000000035 kilograms"

    W.T.F.

    That's almost as stupid as using imperial units.

    0.000000000000035 gigagrams

    There. I fixed it for you.

    --

    "The great thing about multitasking is that several things can go wrong at once." -me

  44. HPG Axis rationalization or push the T-Button? by See+Attached · · Score: 1

    Would a proper diagnosis of Low T, include the FSH and TH levels? Anything else to measure? Does insurance pay for GnRH? Wiki article gets into Leptin/Ghrelin as well. ( http://en.wikipedia.org/wiki/H... ). Simply pushing pellets or topical gels seems really imprudent. We need to treat symptoms less and find out why there is an imbalance. Do Doctors have the support of insurance companies to run the proper tests?

    --
    Time for a new Political party in the US (or two!) One is off the rails Other cant pony up a leader.
  45. including hormon replacement therapy? by mnt · · Score: 1

    14 tonnes, does that include or exclude the use of T for transgender folks?

  46. 6 months on Testosterone supplement.... by MercTech · · Score: 1

    I'm over 50 and plagued by some osteoarthritis from some serious injuries in my younger days.
    I read some of the studies of testosterone use and discussed with my primary care physician. My thought that was if hormone therapy helped women cope with effects of aging, would it help for a man to take such. I had my testosterone levels checked and was prescribed androgel to increase my testosterone levels.

    After six months of using Androgel I've halved the pain and anti-inflammatory medication taken for old knee and rotator cuff injuries. Yep, I think it helps with the effects of aging. Not turning me into a chippendale wannabe but making keeping up an exercise regimen much much easier.

    A 50 something still going....

    --
    NRRPT/RCT
  47. Eat... by Anonymous Coward · · Score: 0

    Eat a good helping of beef every day. You will get enough T from beef to remain viral. This suggestion is coming from a 69 year old man who knows this from experience. 15 mg of zinc is supposed to help also.