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We May Finally Know What Causes Alzheimer's -- and How To Stop It (newscientist.com)
We may finally have found the long-elusive cause of Alzheimer's disease: Porphyromonas gingivalis, the key bacteria in chronic gum disease. New Scientist: That's bad, as gum disease affects around a third of all people. But the good news is that a drug that blocks the main toxins of P. gingivalis is entering major clinical trials this year, and research published Wednesday shows it might stop and even reverse Alzheimer's. There could even be a vaccine. Alzheimer's is one of the biggest mysteries in medicine. As populations have aged, dementia has skyrocketed to become the fifth biggest cause of death worldwide. Alzheimer's constitutes some 70 per cent of these cases and yet, we don't know what causes it.
Just floss people. And don't FORGET to floss. The more you floss, the less you will forget to floss. See how that works?
"If you want to improve, be content to be thought foolish and stupid." - Epictetus
Given the state of the world some days I was kind of looking forward to alzheimers/dementia.
"Poor oral health is a risk factor for Alzheimer’s disease. What’s not clear is whether gum disease causes the disorder or is merely a result"
EDITORS, EDIT !
until you factor in the inevitable greed variable from the Pharmaceutical Cartel.
You know as well as I what they're going to do.
They'll buy it up, crank the price to the point of sheer lunacy and charge folks something like $100,000+ for the treatment.
Even if we have cures for all the diseases that ever existed, until someone regulates the GD Pharmaceutical industry, it will only be an option for the super-rich.
( I'm not about to hand over my entire life's savings to be ' cured ' only to live in financial misery the rest of my life. I'd rather die and give that money to my family. )
I remember twenty/thirty plus years ago when researchers found aluminum ions in the brains of Alzheimer's sufferers and there was the suggestion that cooking without aluminum pots and pans would prevent Alzheimer's. It seems that the aluminum ions were a symptom of Alzheimer's and not a cause - but on the plus side it gave steel cookware a good boost.
If it's true that this bacteria causes Alzheimer's, then it's good news as it should be fairly easy to eradicate.
Mimetics Inc. Twitter
I already know the cause...well I did but I forgot about it. What are we talking about again?
You were saying how much you loved Elon Musk, Tesla, space colonization, AI, self driving cars, and anything else high tech.
"That's the way to do it" - Punch
This finding could be similar in scope to when they found that H Pylori was the cause of most stomach ulcers. Time to go brush and floss!
Aaaaaand we have the perfect slashcomment. Experts say X, someone stops in here, says it's false, provides no links, no proof, just an unflinching assertion.
My grandma had it. My mother has it know, and it's getting worst.
While I do believe it's too late for her, and even if it's available I will never have anything near the amount of money this may require, there is hope for me and my 2 brothers in 20 years (statiscally, one of us should have it).
Alzheimer's is distinct from vascular dementia. From this study:
W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
"If borne out in clinical testing, COR388 could represent a wholly new approach to addressing a disease estimated to affect more than 5.4 million people in the United States." - Business Wire article
I really hope this turns out to be a breakthrough. But as the debunked Buzzfeed story showed us, something prefixed with "if true" isn't necessarily true.
Nahh. I was channeling the experts. Google Type 3 Diabetes.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.
This is about the fifth thing in the past year I've seen that has been called out as the cause of Alzheimer. I really wish the media would stop jumping on these initial papers before they have been fully validated and reproduced.
I browse on +1 so AC's need not respond, I won't see it.
(+5, Confident) is the way things go here lately.
My God, it's Full of Source!
OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
If you're that bothered about the cost of medical care (which I can understand), a very simple way to reduce the cost is to call and *ask*.
My doctor said I needed an MRI and handed me the phone number of an MRI place. I called them and asked the price. It took them about five minutes to figure out it would cost $1,500. I then did a Google search for "Dallas MRI". The very first place listed in the Google search results did it for $450.
A year later my wife needed an MRI. She went to the pace that charges $450, not the place her doctor handed her a card for ($1500 again).
Would you buy a car or even a phone without checking the price? Of course not, but people go buy medical stuff and then wait for a bill, not even asking what their price is.
They were able to find some cases with Alzheimer, but no bacterial infection, perhaps they should look harder? 94% match in a sample size of 54 is hardly a case closed kind of thing. Good work nevertheless, but one should be a bit more careful before declaring groundbreaking success.
In a landmark study I'm totally sure exists somewhere, it was discovered that 100% of Alzheimers were life-long heavy users of the gas "oxygen". With this indisputable evidence in hand researchers say it looks like the end of Alzheimers is in sight. Preventative measures are easy to describe and implementation can happen in the next 5-10 years. Options range from complex operations like shifting to a methane based metabolism or switching to photosynthesis to as simple as preventing air intake to block the absorption of oxygen.
There's a reason they call Alzheimer's Diabetes 3.
"A person is smart. People are dumb, panicky dangerous animals and you know it." - K
It's entirely plausible that he is suffering from some amount of dementia
Unlikely. Dementia is defined as a loss of cognitive functioning. But there is little evidence that Trump is getting worse. He has always been this way, even when he was in his 20s. You can't "lose" something you never had.
https://www.sciencenews.org/ar... I guess I'm glad to see that they're looking for infections as to the cause...
I saw an article that noted that Trump's use of language had deteriorated substantially compared to when he was younger.
https://www.statnews.com/2017/...
Unlikely. Dementia is defined as a loss of cognitive functioning.
I'm well aware of that. And it's quite possible he has experienced some loss of cognitive functioning. I'm not saying he's deep in the grip of Alzheimers or anything like that. 8.8 percent of adults over 65 have some amount dementia so it would hardly be shocking if he's in the early stages. He does and and has done so many "crazy" things that it's pretty hard to judge with any hope of accuracy because we don't have the data even though he's been a public figure for a long time.
But there is little evidence that Trump is getting worse.
You don't know the man even close to well enough to judge that. Nobody reading this comment does including myself. Your guess is as good as mine but my only point is that you cannot simply dismiss it out of hand because you don't have the information to do that. Odds are that he doesn't have it but the odds that he does are too large to dismiss casually.
Thanks. It's posts like this that keep Slashdot interesting, rather then just armchair experts making shit up.
Socialism: a lie told by totalitarians and believed by fools.
Who knew it would also fight brain plaques
One good thing the Trump Presidency has done is that it has shown people how powerless the Presidency really is. Trump hasnt been able to enact a single part of his Domestic agenda (The tax cuts were Ryan's agenda). The Bureaucracy and shadow state run the country not the elected govt.
People in the US like simplistic answers and have a Messiah complex so the office of the Presidency has been overhyped. Even Obama didnt really do anything which the Bureaucracy didn't want him to do.
At least Trump is making it clear that what is happening is not what he wants.
**Life is too short to be serious**
Probably 99% of the time, you can choose whether to go to doctor A, or doctor B down the street. How many times have you been to a doctor? How many of those times had you been shot, or lost a limb?
Unlike car dealers, most medical places don't post their prices on their web site, but you can call and ask. Unless you've been shot, which is 0% of my family's medical costs. I'm kinda old, I've bought medical care for myself or family probably hundreds of times. So far, not even once have we had a life threatening emergency where we had to rush to the nearest emergency room. A few times (less than 2% of medical) we've needed to choose one of three nearby emergency rooms).
Even if I need to see a doctor within the next couple hours, it takes 5-10 minutes to make a couple calls. You can even check into prices at your two nearest ERs TODAY, before you need them.
"The categorization is not embraced by the medical community, though a limited number of published reviews have forwarded putative mechanisms linking Alzheimer's and insulin resistance."
No. This is a first result. If it's found interesting enough (sounds like it should be) *THEN* controlled studies will be done. I don't know that a blind study could be ethically done, however, as even if it doesn't cause Alzheimer's gum disease is a disease, and likely to make you lose your teeth.
OTOH, maybe they'll just do studies where they neutralize the toxin, and if that prevents or cures Alzheimer's that that will probably suffice.
I think we've pushed this "anyone can grow up to be president" thing too far.
It could be that he tries to be more approachable for his constituents.
We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
But we have the nations oldest president, who seems to be getting much of its advice not from experts but from TV Political Pund[i]ts, ...
There are plenty of experts who give the same advice. Trump (and those who don't self-select against it when browsing) can get it from experts as well.
But the media won't cover it. So the only place YOU hear it are from "pundits" (who also get it from experts and) who get enough air time to be noticed - and then flamed by mainstreamers when the advice runs counter to what THEY're pushing at you.
So when Trump follows this advice, it's easy to think he's "getting ... advice not from experts but from TV Political Pund[i]ts". Especially when said mainstreamers push this image at you because they WANT you to believe it.
Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
Another possible explanation: fluoride prevents tooth decay that, in the past, would have left someone mostly toothless by middle age. If you have no teeth, gingivitis probably isn't a major problem. If you have all of your teeth, but minimal dental care (beyond fluoridation during childhood), gingivitis is likely to be a major problem later in life. Fluoride didn't cause the gingivitis, it just fixed enough BIGGER problems for gingivitis itself to become a big problem.
But, given that, theories need to be proven, and clinical trials fail all the time.
I remember this one trial that cause brain cells to leak. Not a good side effect.
-- Tigger warning: This post may contain tiggers! --
I can't there isn't another ER in distance in the event of a real emergency, and the one here is terrible and not just high priced but they are that also. If I have a non-life threatening emergency I would get my wife to drive me 17 miles to the next town before I would go to the local ER.
My wife slipped on the ice while shopping in the next town they where able to see her do x-rays and confirm she didn't brake her ankle before I got there only 20 minutes away but they also found that she had previously broken that ankle years before and that our local ER and doctor didn't see it. She went to specialist and he confirmed for her that yes the brake was on the old x-rays and that the ER and her doctor both missed it.
I often wonder what the morons that mod you up are like in real life. Probably spend a lot of their time scrubbing a carrot. Like you.
Is that a euphemism? 'cause it sounded like a euphemism. I think it's a euphemism.
And, did you notice that they do not defeat the bacteria, just their toxins. So, we would need to be on their pills for the duration. BTW, my mother in law has alzheimers and she has perfect teeth. I know this is anecdotal but definitely proves there are other factors here.
That is incomprehensible.
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Shutdowns occur when the disagreements between the two parties are so severe that no acceptable compromise can be reached before the deadline for funding is reached. This means that each party could end the shutdown by surrendering; blaming this on one particular party does nothing but identify the bias of the writer.
My own opinion is that the shutdown is a good thing and Trump deserves the credit for the shutdown.
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>The categorization is not embraced by the medical community
Well not embraced by the slow ones at least. There's a bucketload of research and the T3D hypothesis is looking pretty strong.
I should use this sig to advertise my book ISBN-13 : 978-1501515132.