This boils down to about.15kg (less than a third of a pound for us yanks) per lot.
For drugs typically employed in milligram quantities, this is a hell of a lot. And spreading it out doesn't make things better, it makes the potential resistance issues WORSE.
I like to think (it has to be!) of a cybernetic ecology where we are free of our labors and joined back to nature, returned to our mammal brothers and sisters, and all watched over by machines of loving grace.
I want an SD card that lasts long and fails gracefully
Go for a "High Endurance" card. They're designed and marketed for use in dash-cams and other loop-recording devices, where constant heavy writing is expected to occur.
Transcend was formerly the gold standard for these, although it now looks like Samsung is the current top performer.
What kind of bizarre prize packaging is that? If you win 72 mil, the last thing you'd care about is any particular car tossed in.
It's probably some sort of mental trick to make the "prize" seem more concrete. Keep in mind, the ideal target of such scams is not a lucid and clear-thinking individual -- rather, it's someone who is in the process of cognitive decline.
Actually looking forward to this. There are a ton of different inexpensive e-bikes available in Asia, but the price and selection around here is not as good (presumably because they are a low-volume specialty item). Then again, this bike probably won't change that part.
Also surprised to hear about the OnStar. Usually don't like subscription services, but would be nice if it has automatic accident reporting (if working correctly).
The issue here is economic, plain and simple. The providers want all of the most lucrative areas [where densities are maximized and their profits will be fat] and they're not interested in locations with poor likely return. So the ONLY ways to address this are to either cover those locations with a national non-profit (i.e. government funded) provider, paid for out of federal taxes, or to write the contracts for existing commercial operators to give them a legal obligation to provide full, national coverage.
I'd also like to point out that the problem faced here is also in some ways similar to the problem of providing healthcare insurance coverage.
This makes little sense; overseas firms want their consultants staffed on a project just as much as US ones
I'm guessing the headhunters in parent poster's US contractor firm function as something like temporary contractors themselves as well -- the headhunter's goals are much shorter-term than the corporation they work for.
Maybe they even get a commission (which is a terrible incentive structure that ensures their goals don't align with the customers').
Or.. they could just pay the corporations to use their workers? Say like.. contract work? You know.. how capitalism work, and not, dare I say it.. communism?
So the question is... why isn't Trump pushing for a way to make it easier to temporarily hire engineers from Boeing and Lockheed-Martin, instead of having NASA hand out contracts to those companies? Or perhaps maybe grab some workers directly from Halliburton, instead of signing a contract that goes through their entire company?
Short answer -- because he personally has a beef with Amazon and Google, seeing that their corporate culture is hostile to his agenda. So in one stroke he seeks to find a way to forgo handing out lucrative government contracts to those companies, while simultaneously weakening them by leeching away talent.
Didi did more than allow an appearance-rating system to emerge. Apparently, they recruited male drivers using suggestive ads, hinting that hook-ups and relationships with female passengers could be a possibility, and promoted a case where a male driver who ended up marrying one of his female passengers.
Looks like the Windows 10 1803 update also prevents the Intel HD graphics driver from changing the screen brightness.
This has been the case since back when Windows 8 came around for me. Every Windows update that messes with the graphics on my ASUS N56dp laptop (AMD trinity APU) breaks the screen brightness. Fortunately, it can be fixed by re-installing the manufacturer's graphics drivers, and/or a registry edit.
We can probably guess why the channel was removed. Some of the videos seemed to be making medical claims about the drugs, and the descriptions had links where you could buy them...
tl;dr is that in the early 1960's, civil-rights proponents (from the progressive faction of the Democratic party) were once the champions of a merit-based immigration system. Opponents (mostly the southern Democratic party faction) championed the blood-tie / family-reuinification system, assuming that since the USA demography was at that time overwhelmingly white and of Western and Northern European descent, a blood-tie based system would serve to preserve the status quo. What they did not anticipate was the collapse in Western/Northern European emigration, as their birth-rates fell and their economies improved.
Not really covered in the article above, is that afterwards the Southern Democrats would flip to the Republican party during the "Southern Strategy" shift, resulting in a scrambling of ideological alignments of both the Democrats and the Republicans that contributed to the modern day mess.
How many non-infectious diseases have ever been cured?
I see a lot of people missing OP's point, answering with infectious diseases. Probably because you need both a medical and a historical background to give him an answer -- once a problem is "cured", the memory and attention dedicated to it fades.
Pellagra, Beri-beri, Scurvy, Rickets, Vitamin A deficiency blindness. All cured with population-scale nutritional supplementation, all so rare now that most doctors in the developed world have never seen a real-life case. Goiter (Iodine-deficiency type), and neural tube defects (folate-deficiency type) less common than in the past.
Not sure if OP is interested in stuff that has been almost wiped out, but requires individual personal medical attention at some point. For instance, Eisenmenger Syndrome is rarely seen these days -- because many of the underlying congenital heart defects that lead to the condition were found by population-level neonatal screens and surgically corrected in infancy.
It just so happens that C. elegans is one of the few multicellular organisms for which all cell fates during development are mostly deterministic and completely known.
The actual worm itself has exactly 302 neurons, and their connections have been mapped.
When reading this article please keep in mind that the study applies to persons with a particular genetic disease called Familial Adenomatous Polyposis (or FAP, huhuhu). Applicability to the general population is uncertain, though the biological mechanism is fascinating.
A fungus finally figured out how to digest lignin, in a process described by biochemists as "untying a knot with a flamethrower". The same process is still used by fungi today, pretty much unaltered.
To add to this description, the way the knot is "tied" is that wood is a cellulose-in-lignin composite, in which the lignin is a combinatorial polymer -- the plant uses several different monomers that are sort-of randomly put together, giving you a very large number of possible products, making it impossible for any reasonably-sized set of enzymes to tackle. As Shanghai Bill described it, the eventual fungal solution was to start by pumping a blast of free radicals into the lignin, breaking it up into fragments that were more amendable to further processing.
This also points to a fundamental problem with the development of cellulosic ethanol -- we haven't managed to speed up the fermentation process much, because wood and other plant structural materials are the end result of a eons-long evolutionary stalemate between plants and microbes. There simply aren't any easy molecular biology shortcuts for digesting it; all approaches appear to have been well-balanced between biological costs incurred by the defender and the attacker.
Of course, maybe we can get around the problem by circumventing the rules of the game. For instance, bulk physical treatment process can pre-degrade plant material (physical conditions aren't accessible to microbes because of scale or biological compatibility, but engineers will still need to make the cost and energy consumption of the process economically worthwhile). Or, genetically engineering plants to produce easily degraded lignins (but this means your biomass crops have unilaterally disarmed one of their defense mechanisms).
Putting a cap on population growth is essentially what the certain areas of California have done, although at a much smaller endpoint.
Under typical historical circumstances, the concentration of economic activity would have led to high-density buildings and eventually skyscrapers and such, followed by construction of the systems to handle the higher density, such as subways. However, restrictions on construction in and around the Bay Area have locked most areas into low-density development. This restricts the resident population to either incumbent residents that bought in the past, or higher-earning newcomers who can afford the exorbitant housing costs. Infrastructure limitations also limit the size of the non-resident worker population that can migrate in/out on a daily basis.
Either way, it's an interesting social experiment in squeezing city-like economic activity into a suburb-like layout.
Pai and crew keep saying that the market should decide, and ignore the fact that there's absolutely no competition for the vast majority of the nation (only one broadband provider in my entire state, for example).
They are absolutely not ignoring it -- in fact, they've already addressed the problem by re-defining one provider as "competition"! https://arstechnica.com/inform...
That's interesting, my friend was in the program since the beginning and they never changed the terms. The only restriction was seeing a movie once, and one movie per day. Never had to take pictures or have a lottery or any of that stuff. Sounds like they were experimenting in certain markets to see what they could get away with.
The other possibility could be that they managed to get some better contracts with some movie theater chains than others. It's possible that if you end up as a consumer who visits the high-cost chains (or high-cost geographical locations), that they end up restricting your visits and trying to push you out -- however, we as end-users would have no idea which ones those happen to be.
Another possibility is that they had suspicions of fraudulent behavior from theater owners, and you happened to unfortunately match some pattern.
Slashdot Mirror
This boils down to about .15kg (less than a third of a pound for us yanks) per lot.
For drugs typically employed in milligram quantities, this is a hell of a lot. And spreading it out doesn't make things better, it makes the potential resistance issues WORSE.
I like to think
(it has to be!)
of a cybernetic ecology
where we are free of our labors
and joined back to nature,
returned to our mammal
brothers and sisters,
and all watched over
by machines of loving grace.
I'd rather listen to Daniwell's version of Miku Hatsune singing 10,000 digits of Pi:
https://www.nicovideo.jp/watch...
I want an SD card that lasts long and fails gracefully
Go for a "High Endurance" card. They're designed and marketed for use in dash-cams and other loop-recording devices, where constant heavy writing is expected to occur.
Transcend was formerly the gold standard for these, although it now looks like Samsung is the current top performer.
What kind of bizarre prize packaging is that? If you win 72 mil, the last thing you'd care about is any particular car tossed in.
It's probably some sort of mental trick to make the "prize" seem more concrete. Keep in mind, the ideal target of such scams is not a lucid and clear-thinking individual -- rather, it's someone who is in the process of cognitive decline.
Actually looking forward to this. There are a ton of different inexpensive e-bikes available in Asia, but the price and selection around here is not as good (presumably because they are a low-volume specialty item). Then again, this bike probably won't change that part.
Also surprised to hear about the OnStar. Usually don't like subscription services, but would be nice if it has automatic accident reporting (if working correctly).
The issue here is economic, plain and simple. The providers want all of the most lucrative areas [where densities are maximized and their profits will be fat] and they're not interested in locations with poor likely return. So the ONLY ways to address this are to either cover those locations with a national non-profit (i.e. government funded) provider, paid for out of federal taxes, or to write the contracts for existing commercial operators to give them a legal obligation to provide full, national coverage.
I'd also like to point out that the problem faced here is also in some ways similar to the problem of providing healthcare insurance coverage.
This makes little sense; overseas firms want their consultants staffed on a project just as much as US ones
I'm guessing the headhunters in parent poster's US contractor firm function as something like temporary contractors themselves as well -- the headhunter's goals are much shorter-term than the corporation they work for.
Maybe they even get a commission (which is a terrible incentive structure that ensures their goals don't align with the customers').
Or.. they could just pay the corporations to use their workers? Say like.. contract work? You know.. how capitalism work, and not, dare I say it.. communism?
So the question is... why isn't Trump pushing for a way to make it easier to temporarily hire engineers from Boeing and Lockheed-Martin, instead of having NASA hand out contracts to those companies? Or perhaps maybe grab some workers directly from Halliburton, instead of signing a contract that goes through their entire company?
Short answer -- because he personally has a beef with Amazon and Google, seeing that their corporate culture is hostile to his agenda. So in one stroke he seeks to find a way to forgo handing out lucrative government contracts to those companies, while simultaneously weakening them by leeching away talent.
Didi did more than allow an appearance-rating system to emerge. Apparently, they recruited male drivers using suggestive ads, hinting that hook-ups and relationships with female passengers could be a possibility, and promoted a case where a male driver who ended up marrying one of his female passengers.
https://www.nytimes.com/2018/0...
Use an old processor without speculative execution features? Some lower end ARMs and Atoms also are immune, I think.
Brands that I'll currently do
On the chance you've worked with them, any experience with Hyundai's aftermarket supply?
Pinging Roblimo: Packet loss 100%
Er, too soon?
Looks like the Windows 10 1803 update also prevents the Intel HD graphics driver from changing the screen brightness.
This has been the case since back when Windows 8 came around for me. Every Windows update that messes with the graphics on my ASUS N56dp laptop (AMD trinity APU) breaks the screen brightness. Fortunately, it can be fixed by re-installing the manufacturer's graphics drivers, and/or a registry edit.
things like competition for survival and for mating and for eating
Well, 2 out of 3 ain't bad, I guess.
We can probably guess why the channel was removed. Some of the videos seemed to be making medical claims about the drugs, and the descriptions had links where you could buy them...
It might also have something to do with what happened to Google back in 2011 , where they settled a case with the US Department of Justice regarding advertisements for rogue online pharmacies, for $500m.
Followed by a shareholder lawsuit regarding the same issue, which they settled for something like $250m.
The idea of Merit-based immigration has a rather interesting history here in the US:
https://www.theatlantic.com/bu...
tl;dr is that in the early 1960's, civil-rights proponents (from the progressive faction of the Democratic party) were once the champions of a merit-based immigration system. Opponents (mostly the southern Democratic party faction) championed the blood-tie / family-reuinification system, assuming that since the USA demography was at that time overwhelmingly white and of Western and Northern European descent, a blood-tie based system would serve to preserve the status quo. What they did not anticipate was the collapse in Western/Northern European emigration, as their birth-rates fell and their economies improved.
Not really covered in the article above, is that afterwards the Southern Democrats would flip to the Republican party during the "Southern Strategy" shift, resulting in a scrambling of ideological alignments of both the Democrats and the Republicans that contributed to the modern day mess.
I see a lot of people missing OP's point, answering with infectious diseases. Probably because you need both a medical and a historical background to give him an answer -- once a problem is "cured", the memory and attention dedicated to it fades.
Pellagra, Beri-beri, Scurvy, Rickets, Vitamin A deficiency blindness. All cured with population-scale nutritional supplementation, all so rare now that most doctors in the developed world have never seen a real-life case. Goiter (Iodine-deficiency type), and neural tube defects (folate-deficiency type) less common than in the past.
Not sure if OP is interested in stuff that has been almost wiped out, but requires individual personal medical attention at some point. For instance, Eisenmenger Syndrome is rarely seen these days -- because many of the underlying congenital heart defects that lead to the condition were found by population-level neonatal screens and surgically corrected in infancy.
It just so happens that C. elegans is one of the few multicellular organisms for which all cell fates during development are mostly deterministic and completely known.
The actual worm itself has exactly 302 neurons, and their connections have been mapped.
http://www.wormatlas.org/herma...
When reading this article please keep in mind that the study applies to persons with a particular genetic disease called Familial Adenomatous Polyposis (or FAP, huhuhu). Applicability to the general population is uncertain, though the biological mechanism is fascinating.
Brain-Dead Teen, Only Capable Of Rolling Eyes And Texting, To Be Euthanized:
https://www.theonion.com/brain...
A fungus finally figured out how to digest lignin, in a process described by biochemists as "untying a knot with a flamethrower". The same process is still used by fungi today, pretty much unaltered.
To add to this description, the way the knot is "tied" is that wood is a cellulose-in-lignin composite, in which the lignin is a combinatorial polymer -- the plant uses several different monomers that are sort-of randomly put together, giving you a very large number of possible products, making it impossible for any reasonably-sized set of enzymes to tackle. As Shanghai Bill described it, the eventual fungal solution was to start by pumping a blast of free radicals into the lignin, breaking it up into fragments that were more amendable to further processing.
This also points to a fundamental problem with the development of cellulosic ethanol -- we haven't managed to speed up the fermentation process much, because wood and other plant structural materials are the end result of a eons-long evolutionary stalemate between plants and microbes. There simply aren't any easy molecular biology shortcuts for digesting it; all approaches appear to have been well-balanced between biological costs incurred by the defender and the attacker.
Of course, maybe we can get around the problem by circumventing the rules of the game. For instance, bulk physical treatment process can pre-degrade plant material (physical conditions aren't accessible to microbes because of scale or biological compatibility, but engineers will still need to make the cost and energy consumption of the process economically worthwhile). Or, genetically engineering plants to produce easily degraded lignins (but this means your biomass crops have unilaterally disarmed one of their defense mechanisms).
Putting a cap on population growth is essentially what the certain areas of California have done, although at a much smaller endpoint.
Under typical historical circumstances, the concentration of economic activity would have led to high-density buildings and eventually skyscrapers and such, followed by construction of the systems to handle the higher density, such as subways. However, restrictions on construction in and around the Bay Area have locked most areas into low-density development. This restricts the resident population to either incumbent residents that bought in the past, or higher-earning newcomers who can afford the exorbitant housing costs. Infrastructure limitations also limit the size of the non-resident worker population that can migrate in/out on a daily basis.
Either way, it's an interesting social experiment in squeezing city-like economic activity into a suburb-like layout.
Pai and crew keep saying that the market should decide, and ignore the fact that there's absolutely no competition for the vast majority of the nation (only one broadband provider in my entire state, for example).
They are absolutely not ignoring it -- in fact, they've already addressed the problem by re-defining one provider as "competition"!
https://arstechnica.com/inform...
That's interesting, my friend was in the program since the beginning and they never changed the terms. The only restriction was seeing a movie once, and one movie per day. Never had to take pictures or have a lottery or any of that stuff. Sounds like they were experimenting in certain markets to see what they could get away with.
The other possibility could be that they managed to get some better contracts with some movie theater chains than others. It's possible that if you end up as a consumer who visits the high-cost chains (or high-cost geographical locations), that they end up restricting your visits and trying to push you out -- however, we as end-users would have no idea which ones those happen to be.
Another possibility is that they had suspicions of fraudulent behavior from theater owners, and you happened to unfortunately match some pattern.