Not to mention that dune 2 invented the RTS. I think. Maybe something else came first, but dune 2 definitely came before warcraft. At least, I played it before warcraft...
Sequence similiarity tends to imply structural similarity. Find another protein with a similar peptide sequence and a known structure, use this structure as your search query, and you've got a pretty good guess of what your protein might look like. Better yet, you've got a good starting point for your hackish protein folding method (monte carlo, genetic algorithm, neural networks, whatever)
The implication both from the summary and from the article itself is that this new search is just as thorough as other search methods but much faster. To prove thoroughness they would have had to show that anything found by other search methods will also be found by their new, much faster, search method. I doubt very much that they were able to do prove this rigorously.
...the only way to guarantee an optimum match is by exhaustive search... I haven't read the paper, but I don't think this (a thorough comparison) is as hard as you think it is. The bioinformatics community is pretty good about sharing datasets and software. There are benchmarks datasets that researchers use for comparing shape-matching techniques. Pick, say, 100 query molecules and a database of 10,000 molecules. Search the database for each query, 1,000,000 queries, multiplied by the number of techniques you're comparing. Not that much work. Throw in Kabsch-style cRMS matching as a ground truth, and you're standing on pretty solid ground. Like I said though, I haven't read it, so who knows if they did this.
For any difficult optimization problem, there's bound be a hack that works very nicely. Maybe they found the hack.
viruses aren't alive. they're just chunks of dna coated in protein. so they don't have lifespans. but that's not to say that they aren't fragile. your point is valid.
Don't throw your SB Live away yet. Try the kx drivers. They're incredible. Open source too. I haven't bought a soundcard in ages, but if these SB Lives you're talking about are still based on the EMU10K chip, then this is all you need. The only reason to buy a more expensive card is if you need good analog ins/outs. For home recording, then 1/8 inchers on the SB Live are fine. If you're like me (and like the poster, from what it sounds like) and all the audio stays in the digital domain, then you really can't beat an EMU10K-based card with kx drivers.
I should note that I'm one of those people who thinks that most people are full of bullshit when it comes to comparing audio products. I can't judge things like "warmth" and "clarity." The only basis I have for saying these drivers are hot shit is that they give ~5ms latencies. True, internal cards may be noisy, but I have good hearing and I don't hear any noise. Maybe they "muddy" up the sound or whatever, but thats probably just bullshit.
That "usability enhancement" is absolutely terrible, I agree. But I think it's GTK's fault. Well, not really, because with other GTK apps (gimp) you can right click and get an "open location" or "open path" option, or something like that, and it gives you a simple text box in which you can type filesystem paths, and even do tab-completion. Of course, the Firefox wizards haven't yet seen the reason to enable this feature. So I guess you have them to blame.
call the local junior high marching band
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Gadgets for the Lazy
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· Score: -1, Flamebait
for fucks sake. taps on the bugle is the easiest thing to play. its like chopsticks on the piano. all is lost.
The US has nowhere near 4factorial = 24 time zones. If that were true, the sun would never set on the you-know-what. There's 5 time zones in the lower 48: pacific, rocky, central, eastern and atlantic (most people forget that Maine is +1 from New York.) Hawaii is 3 hours away from the pacific timezone (I think...) and Alaska fits in there somewhere. Don't even get me started on Guam and Samoa. So its 8 timezones, tops. Nowhere near 4! = 24.
It "seems" to shock the fish back to life, except the movie fades out just seconds after that. If you put electricity through a dead body, it will move. The fish jerks a little, but it doesn't swim around like it does at the beginning of the video. There's no fucking way that fish withstood all that co2. And if it did, its little fish balls would be shrunk out of existence from all the yellow5...or is it the yellow6?
I guess all the budget cutbacks at NASA have forced them to make the scientists write the articles. This must be a result of the budget problems. The scientists are writing their own copy now, too.
I'm having trouble understanding what is peculiar about this particular legal issue. Could someone please highlight the important points for me, making liberal use of bold and italics?
Word to that. The only people I talked to who were genuinely intrigued by the philosophical questions that the matrix set forth were, to be blunt, stupid and uneducated. I didn't say that to their faces though cause they were also violent gun-loving types. The rest of us dealt with the question of "what is reality" in highschool english class cause we were paying attention when they talked about Plato. We didn't find it that interesting, though, cause there weren't any guns or robots.
If the matrix was the first thing to make you ponder these types of questions then either you're very young or you just don't think much.
Re:You forgot to mention tabs, so I will.
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Safari Beta Updated
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· Score: 1
haha smartass. very funny. Yes, I did figure it out about a second after i posted.
Slashdot Mirror
Not to mention that dune 2 invented the RTS. I think. Maybe something else came first, but dune 2 definitely came before warcraft. At least, I played it before warcraft...
Sequence similiarity tends to imply structural similarity. Find another protein with a similar peptide sequence and a known structure, use this structure as your search query, and you've got a pretty good guess of what your protein might look like. Better yet, you've got a good starting point for your hackish protein folding method (monte carlo, genetic algorithm, neural networks, whatever)
...the only way to guarantee an optimum match is by exhaustive search... I haven't read the paper, but I don't think this (a thorough comparison) is as hard as you think it is. The bioinformatics community is pretty good about sharing datasets and software. There are benchmarks datasets that researchers use for comparing shape-matching techniques. Pick, say, 100 query molecules and a database of 10,000 molecules. Search the database for each query, 1,000,000 queries, multiplied by the number of techniques you're comparing. Not that much work. Throw in Kabsch-style cRMS matching as a ground truth, and you're standing on pretty solid ground. Like I said though, I haven't read it, so who knows if they did this.For any difficult optimization problem, there's bound be a hack that works very nicely. Maybe they found the hack.
Red badges are the new hot accessory this season. All the cool kids are wearing them.
viruses aren't alive. they're just chunks of dna coated in protein. so they don't have lifespans. but that's not to say that they aren't fragile. your point is valid.
http://kxproject.lugosoft.com/
Don't throw your SB Live away yet. Try the kx drivers. They're incredible. Open source too. I haven't bought a soundcard in ages, but if these SB Lives you're talking about are still based on the EMU10K chip, then this is all you need. The only reason to buy a more expensive card is if you need good analog ins/outs. For home recording, then 1/8 inchers on the SB Live are fine. If you're like me (and like the poster, from what it sounds like) and all the audio stays in the digital domain, then you really can't beat an EMU10K-based card with kx drivers.
I should note that I'm one of those people who thinks that most people are full of bullshit when it comes to comparing audio products. I can't judge things like "warmth" and "clarity." The only basis I have for saying these drivers are hot shit is that they give ~5ms latencies. True, internal cards may be noisy, but I have good hearing and I don't hear any noise. Maybe they "muddy" up the sound or whatever, but thats probably just bullshit.
That "usability enhancement" is absolutely terrible, I agree. But I think it's GTK's fault. Well, not really, because with other GTK apps (gimp) you can right click and get an "open location" or "open path" option, or something like that, and it gives you a simple text box in which you can type filesystem paths, and even do tab-completion. Of course, the Firefox wizards haven't yet seen the reason to enable this feature. So I guess you have them to blame.
for fucks sake. taps on the bugle is the easiest thing to play. its like chopsticks on the piano. all is lost.
The US has nowhere near 4factorial = 24 time zones. If that were true, the sun would never set on the you-know-what. There's 5 time zones in the lower 48: pacific, rocky, central, eastern and atlantic (most people forget that Maine is +1 from New York.) Hawaii is 3 hours away from the pacific timezone (I think...) and Alaska fits in there somewhere. Don't even get me started on Guam and Samoa. So its 8 timezones, tops. Nowhere near 4! = 24.
Central limit theorem is totally played out. So is e=mc^2. Where's the hot new theorems of today's generation?
http://en.wikipedia.org/wiki/Lynne_Thigpen
How old are you? Didn't your teacher tell you that you can't just make up 'illions, like gillions and zillions?
It "seems" to shock the fish back to life, except the movie fades out just seconds after that. If you put electricity through a dead body, it will move. The fish jerks a little, but it doesn't swim around like it does at the beginning of the video. There's no fucking way that fish withstood all that co2. And if it did, its little fish balls would be shrunk out of existence from all the yellow5...or is it the yellow6?
The movie is fish snuff.
I drink Pabst from a can at even the most respectable establishments.
Getting work done? You make it sound so easy...
compare einstein's income with bill gates'. cue mr show music.
I'd imagine your girlfriend would be more upset to find you jerking off to puppies, rather than women.
I guess all the budget cutbacks at NASA have forced them to make the scientists write the articles. This must be a result of the budget problems. The scientists are writing their own copy now, too.
Actually the only safe way to drive is in an amphibious tank. If we all drove amphibious tanks, no one would ever die. Not even from the cancer.
I'm having trouble understanding what is peculiar about this particular legal issue. Could someone please highlight the important points for me, making liberal use of bold and italics?
does stillbirth count as birth control?
it took four people to come up with that!
It wouldn't beep at bulk foods, procured via fair trade by natural food co-ops. But wait, those don't have bar codes...
Word to that. The only people I talked to who were genuinely intrigued by the philosophical questions that the matrix set forth were, to be blunt, stupid and uneducated. I didn't say that to their faces though cause they were also violent gun-loving types. The rest of us dealt with the question of "what is reality" in highschool english class cause we were paying attention when they talked about Plato. We didn't find it that interesting, though, cause there weren't any guns or robots.
If the matrix was the first thing to make you ponder these types of questions then either you're very young or you just don't think much.
haha smartass. very funny. Yes, I did figure it out about a second after i posted.