Sound does travel through the 'vacuum.'
As any self respecting scientist will know, the medium through the sound propagates is the 'Aether,' a very diffuse, gas-like material.
Not true.
DFT has been shown over and over again to fail at modelling weak, non-formally bonding systems. These include absolutely important things such as H-bonding, pi-interactions, vdW forces, etc.
For THOSE systems, one has to go back to even earlier than the mid-60's, and go back to Moller - Plesset, and Perturbation Theory, the beast that that is.
Density Functional Theory is popular for a couple of reasons, from what I have seen:
(a) It is faster.
(b) Everyone is in a mad rush to model enzymes, large molecules that they are.
In essence, to effectively model something like an enzyme, you have to set up a system with something around 150 atoms, which means about 1000 or so electrons, and considering that the truly accurate methods scale N^5 to N^7 (QCISD), you find yourself defaulting to DFT, which does so at about N^4. In this case, N is an arbitrary factor representing (cpu cycles)/electron.
As a caveat, my experience ranges B3LYP, uniquely, and not PW91, or any of the other ones. Furthermore, I am not sure if any of the Dunning basis sets are in some way an improvement over the Pople-style ones.
All of these things you have quoted are, in essence, side effects of a drug. And here is the rub: Will the powers that be actually go ahead and regulate GM food as a drug, the way it ought to be?
I am sugesting that it be regulated in that sense not on the basis of some therapeutic effect that the GM food may have, but, rather, on the potential for side effects that it might cause in the public that consumes it. This matter alone is enough to warrant additional governmental regulation.
There are instances left and right of drugs being safe for the US populace at large, only to find out that there was some kind of a lethal interaction with a strange recessive trait of people with weird asian tribe ascendancy. This points at the number one reason why GM is, in general, a bad thing: That, in introducing strange genetic sequences into the food chain, you might end up with far more than you initially bargained for.
Frankly, we don't understand the mechanisms of life so well that we can go about getting all entrepeneurial with what little we do know.
I have actually found that the graphing functionality in calculators are little more than a gimmick for insecure college students. The quality of the graph that the LCD screen will provide you with is just too low to really provide you with insight, and couple with the slowness of these instruments, you are essentially dealing with what is basically a waste of time and money, when you least can afford it: when you are a broke student during a cal final. For that matter alone, one cannot overemphasize the need to culture the skill that is analytic geometry, i.e. the ability to skillfully build a graph by simple inspection of the equation provided. All information that is relevant can be generated with some skill, without a calculator doing it for you, with more speed and accuracy.
There is another issue that I am not sure was touched upon, either in the article, or in any of the posts I was patient enough to read up until now. This issue is that of the 'surface tension' of the bulk product. By this I mean that there is a thermodynamic drive to make particles of a certain size: anything smaller than this size, which varies from one material to another, and you get instability. For those of you that like fancy catch phrases, think in terms of Brownian Motion, and in Quantum Confinement: There are concerns that we are reaching a lower limit for detail on cpu's because of these very same things. Now, the engineering problems that are caused by these quantum mechanical effects are non trivial, to say the least, and just controlling the shape of something too small to manipulate is a massive problem that takes years to deduce: you have to manipulate phase transitions from one crystal form to another, vary concentrations....etc, etc. It is no surprise to me that this is taking so long.
And here is a somewhat clear and concise explanation: "In the mathematics of manifolds and differential operators, the Atiyah-Singer index theorem is a basic general result that came at the end of a long development on the theory of elliptic operators (such as Laplacians), going back to the Riemann-Roch theorem. There have been a number of subsequent developments, in particular in the work of Alain Connes.
We start with a compact smooth manifold (without boundary) and an elliptic operator E on it. Here E is a differential operator acting on smooth sections of a given vector bundle. The property of being elliptic is expressed by a symbol s that can be seen as coming from the coefficients of the highest order part of E; s is a bundle section and required to be non-zero. E.g. for a Laplacian s is a positive-definite quadratic form.
By some basic analytic theory the differential operator E gives rise to a Fredholm operator. Such a Fredholm operator has an index, defined as the difference between the dimension of the kernel of E (solutions of Ef = 0, the harmonic functions in a general sense) and the dimension of the cokernel of E (the constraints on the right-hand-side of an inhomogeneous equation like Ef = g)." Which leads me to wonder: HUH!?
Not unlike what Abbott did.
Newsweek came out with a front page story 'THE COMING ARTHRITIS EPIDEMIC'
2 weeks later, Abbott rolled out Humira, its new TNF-Alpha rheumathoid arthritis drug.
In most cases the inhouse R&D of these pharmas is not what is generating the new intellectual property: it is the purchase of patents from other companies that does it - the advances you see are probably the work of some brilliant professor, rather than some R&D drone in the bowels of one of these corporations.
You obviously do not live in Chicago.
The CPD is the best Police Department that money can buy, the joke goes. And out of this you expect some kind of responsible oversight?
You can say that the judges here will be effective at overseeing this largely thuggish band of cops, but you are wrong: The Chicago courts are known to be the most corrupt in the nation.
You may be right when mentioning these 'implicit controls' with regards to a smaller, relatively wealthier city, but not for Chicago.
There is a strong and justified current of paranoia and cynicism directed at the CPD in the city.
Yes, I read that link a while ago. I was struck by how much SENSE it made, given the logic presented in the letter published by Toledo's government.
This is inline with Israel's policy as of late to stop purchasing closed source software, such as that made by MSFT.
Yes, the $29 DVD player sold at Walmart, that motivated that fatso stampede, crushing some poor woman, and sending her to the hospital. http://news.bbc.co.uk/2/hi/americas/324 9574.stm
Slashdot Mirror
I think?
....He should step away from it....
I, for one, welcome our new Santa Overlords. HAPPY HOLIDAYS!
Sound does travel through the 'vacuum.' As any self respecting scientist will know, the medium through the sound propagates is the 'Aether,' a very diffuse, gas-like material.
Not true. DFT has been shown over and over again to fail at modelling weak, non-formally bonding systems. These include absolutely important things such as H-bonding, pi-interactions, vdW forces, etc. For THOSE systems, one has to go back to even earlier than the mid-60's, and go back to Moller - Plesset, and Perturbation Theory, the beast that that is. Density Functional Theory is popular for a couple of reasons, from what I have seen: (a) It is faster. (b) Everyone is in a mad rush to model enzymes, large molecules that they are. In essence, to effectively model something like an enzyme, you have to set up a system with something around 150 atoms, which means about 1000 or so electrons, and considering that the truly accurate methods scale N^5 to N^7 (QCISD), you find yourself defaulting to DFT, which does so at about N^4. In this case, N is an arbitrary factor representing (cpu cycles)/electron. As a caveat, my experience ranges B3LYP, uniquely, and not PW91, or any of the other ones. Furthermore, I am not sure if any of the Dunning basis sets are in some way an improvement over the Pople-style ones.
So we are basically in FDA land.
All of these things you have quoted are, in essence, side effects of a drug.
And here is the rub: Will the powers that be actually go ahead and regulate GM food as a drug, the way it ought to be?
I am sugesting that it be regulated in that sense not on the basis of some therapeutic effect that the GM food may have, but, rather, on the potential for side effects that it might cause in the public that consumes it. This matter alone is enough to warrant additional governmental regulation.
There are instances left and right of drugs being safe for the US populace at large, only to find out that there was some kind of a lethal interaction with a strange recessive trait of people with weird asian tribe ascendancy.
This points at the number one reason why GM is, in general, a bad thing: That, in introducing strange genetic sequences into the food chain, you might end up with far more than you initially bargained for.
Frankly, we don't understand the mechanisms of life so well that we can go about getting all entrepeneurial with what little we do know.
Not too different from the marketing geniuses that sell hotdogs in 1o packs, and hotdog buns in 12 packs.
I have actually found that the graphing functionality in calculators are little more than a gimmick for insecure college students. The quality of the graph that the LCD screen will provide you with is just too low to really provide you with insight, and couple with the slowness of these instruments, you are essentially dealing with what is basically a waste of time and money, when you least can afford it: when you are a broke student during a cal final.
For that matter alone, one cannot overemphasize the need to culture the skill that is analytic geometry, i.e. the ability to skillfully build a graph by simple inspection of the equation provided. All information that is relevant can be generated with some skill, without a calculator doing it for you, with more speed and accuracy.
There is another issue that I am not sure was touched upon, either in the article, or in any of the posts I was patient enough to read up until now. This issue is that of the 'surface tension' of the bulk product.
By this I mean that there is a thermodynamic drive to make particles of a certain size: anything smaller than this size, which varies from one material to another, and you get instability. For those of you that like fancy catch phrases, think in terms of Brownian Motion, and in Quantum Confinement: There are concerns that we are reaching a lower limit for detail on cpu's because of these very same things.
Now, the engineering problems that are caused by these quantum mechanical effects are non trivial, to say the least, and just controlling the shape of something too small to manipulate is a massive problem that takes years to deduce: you have to manipulate phase transitions from one crystal form to another, vary concentrations....etc, etc.
It is no surprise to me that this is taking so long.
And here is a somewhat clear and concise explanation:
"In the mathematics of manifolds and differential operators, the Atiyah-Singer index theorem is a basic general result that came at the end of a long development on the theory of elliptic operators (such as Laplacians), going back to the Riemann-Roch theorem. There have been a number of subsequent developments, in particular in the work of Alain Connes.
We start with a compact smooth manifold (without boundary) and an elliptic operator E on it. Here E is a differential operator acting on smooth sections of a given vector bundle. The property of being elliptic is expressed by a symbol s that can be seen as coming from the coefficients of the highest order part of E; s is a bundle section and required to be non-zero. E.g. for a Laplacian s is a positive-definite quadratic form.
By some basic analytic theory the differential operator E gives rise to a Fredholm operator. Such a Fredholm operator has an index, defined as the difference between the dimension of the kernel of E (solutions of Ef = 0, the harmonic functions in a general sense) and the dimension of the cokernel of E (the constraints on the right-hand-side of an inhomogeneous equation like Ef = g)."
Which leads me to wonder:
HUH!?
NO! SP! WOOOT
Yay Computational Chemistry is my Future. WUUUUNDERFUL I am an ADONIS in Chat room, though. :D
It becomes the functional equivalent of tossing the English Alphabet at a million monkeys. Shakespeare will NOT emerge from it.
Not unlike what Abbott did. Newsweek came out with a front page story 'THE COMING ARTHRITIS EPIDEMIC' 2 weeks later, Abbott rolled out Humira, its new TNF-Alpha rheumathoid arthritis drug. In most cases the inhouse R&D of these pharmas is not what is generating the new intellectual property: it is the purchase of patents from other companies that does it - the advances you see are probably the work of some brilliant professor, rather than some R&D drone in the bowels of one of these corporations.
Are you guys MS plants? Trying to change the groupthink in here?
Oh yeah, that works. The government decides it doesn't like my ugly mug, and tosses me in prison for 2 years. Yep, sounds like justice to me, alright.
As if. Colombia has a couple of cities worse than this one. Not to mention Sao Paulo.
You obviously do not live in Chicago. The CPD is the best Police Department that money can buy, the joke goes. And out of this you expect some kind of responsible oversight? You can say that the judges here will be effective at overseeing this largely thuggish band of cops, but you are wrong: The Chicago courts are known to be the most corrupt in the nation. You may be right when mentioning these 'implicit controls' with regards to a smaller, relatively wealthier city, but not for Chicago. There is a strong and justified current of paranoia and cynicism directed at the CPD in the city.
Yes, I read that link a while ago. I was struck by how much SENSE it made, given the logic presented in the letter published by Toledo's government. This is inline with Israel's policy as of late to stop purchasing closed source software, such as that made by MSFT.
Take a crap, perhaps?
Sounds like a Joel Siegel review for KPAX: I rate this movie as: "A+ LOVED IT!!!!! FANTASTIC!!!!"
w00000T~~
BUT CAN IT RUN LINUX?
Probably not cynical. But definitely a bastard!!
Yes, the $29 DVD player sold at Walmart, that motivated that fatso stampede, crushing some poor woman, and sending her to the hospital.4 9574.stm
http://news.bbc.co.uk/2/hi/americas/32