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MIT Shows How to Shut Down Brain With Light

An anonymous reader writes "The MIT home-page story today is about a way to use light to shut down brain activity. "Scientists at the MIT Media Lab have invented a way to reversibly silence brain cells using pulses of yellow light, offering the prospect of controlling the haywire neuron activity that occurs in diseases such as epilepsy and Parkinson's disease."

223 comments

  1. There are easier ways by joe_cot · · Score: 5, Funny

    There are easier ways to shut down brain activity. 4chan comes to mind.

    1. Re:There are easier ways by Anonymous Coward · · Score: 0

      Its an amber light for mind control though ....

    2. Re:There are easier ways by drwiii · · Score: 5, Funny

      Rule 1 violation.

    3. Re:There are easier ways by Anonymous Coward · · Score: 0

      Violation of rule 1 and 2.
      The Party Van will pick you up in 20 minutes.


      - we are anonymous, we are legion

    4. Re:There are easier ways by Anonymous Coward · · Score: 0

      In b4 b&.

      p.s. if you don't know why he put that on, you need to lurk moar. ALOT moar.

    5. Re:There are easier ways by Majik+Sheff · · Score: 0, Offtopic

      Holy crap there are a lot of /b/tards on Slashdot. I never knew! In b4 offtopic mod.

      --
      Women are like electronics: you don't know how damaged they are until you try to turn them on.
    6. Re:There are easier ways by Anonymous Coward · · Score: 0

      Anonymous cannot tolerate blinking backgrounds
      Firefox : View -> Style -> Basic Page Style
      Opera : Opera sucks sure there's an ebuild for opera but it just get dropped to /opt, it's statically linked, and it's CLOSED SOURCE, which means that it is a BINARY package.
      IE : Enjoy your AIDS
    7. Re:There are easier ways by Anonymous Coward · · Score: 0

      This is the opposite of my findings. Take away all light, and my brain activity ceases and I begin to snore.

    8. Re:There are easier ways by dosle · · Score: 1

      B&!

    9. Re:There are easier ways by Anonymous Coward · · Score: 0

      I for one think a much better idea would be to find a way to turn *on* people's brain actually. ;-)

    10. Re:There are easier ways by Anonymous Coward · · Score: 1, Funny

      FORTRAN?

    11. Re:There are easier ways by Profane+MuthaFucka · · Score: 1

      4chan cums to mind? WTF?

      --
      Fascism trolls keeping me up every night. When I starts a preachin', he HITS ME WITH HIS REICH!
    12. Re:There are easier ways by Anonymous Coward · · Score: 0

      They tried that first. While it did shut down most higher level reasoning skills, all of their test subjects became obsessed with 'cockmongler' and 'longcat', and wouldn't shut up about something called 'cracky', so they had to go with the light thing.

    13. Re:There are easier ways by Nemetroid · · Score: 1

      The number of replies to this post modded "Offtopic" is astounding.

    14. Re:There are easier ways by beckerist · · Score: 1

      /. has jaded me. All I have to see is a line that stars with "I for one" and I get a little verklempt.

      Back on topic, I wonder if they will find any correlation between this and the fact people see lights as their brains are shutting down (dying). I've heard the "random firing neurons" theory for this, and it sounds awfully similar...

    15. Re:There are easier ways by Anonymous Coward · · Score: 1, Funny

      Rules 1, 2 and 3, namefags! Anonymous does not forgive!

    16. Re:There are easier ways by HTH+NE1 · · Score: 1

      Its an amber light for mind control though ....
      I'm glad I switched to a green phosphor display!
      --
      Oh, say does that Star-Spangled Banner entwine / The myrtle of Venus with Bacchus's vine?
    17. Re:There are easier ways by Anonymous Coward · · Score: 0

      violation of internet rules #1 and #2.

      gb2/gaia fag

    18. Re:There are easier ways by The+Relentless · · Score: 2, Insightful

      Using light? I've had a lot of professors that seemed to be able to shut down brains using sound. Generally their own voice was sufficient.

    19. Re:There are easier ways by Anonymous Coward · · Score: 0

      A .40 caliber round would do the same.

    20. Re:There are easier ways by Anonymous Coward · · Score: 0

      That's because for every Anonymous who understands 4chan memes, there's a Slashdot moderator who doesn't. I'm actually kind of surprised 4chan hasn't declared a raid on this thread, getting on the /b/tard Slashbots to mod comments up.

      (P.S. I already used my mod points, /b/rothers. I need /b/lackup!)

    21. Re:There are easier ways by Anonymous Coward · · Score: 0

      /b/rother, I'm surprised to find you here.

      It's funny that I see a few slashdottisms over at 4chan, but never quite thought the change would arrive or the opposite. So, I want MOAR of this.

    22. Re:There are easier ways by Tatarize · · Score: 1

      They stated that the process is reversible. I frankly don't think it is at all practical. They would have to fiddle with out genes to give this the ability to work. Perhaps they should keep checking and just find the gene that fixes the problem itself.

      --

      It is no longer uncommon to be uncommon.
    23. Re:There are easier ways by Anonymous Coward · · Score: 0

      WORLDS ARE COLLIDING

  2. Who wants to bet... by Anonymous Coward · · Score: 5, Funny

    ...that this is actually a plan to invent the Neuralizer from Men in Black?

    1. Re:Who wants to bet... by mrjatsun · · Score: 1, Funny

      ***** FLASH *****

      Nothing to see here, please move along to the next topic..

    2. Re:Who wants to bet... by Verte · · Score: 0

      Perhaps even human EPROMs?

      --
      We at slashdot are scientists, specialists and kernel hackers. Your FUD will be found out.
    3. Re:Who wants to bet... by JohnnyLocust · · Score: 1

      ...that this is actually a plan to invent the Neuralizer from Men in Black?

      Nah. I think they're trying to make the Disco-Hypno gun from "Looker"
      http://www.imdb.com/title/tt0082677/
    4. Re:Who wants to bet... by savorymedia · · Score: 1

      I'm not sure...but how much do you want to bet the gov't will take this info and build some kind of "riot suppression" weapon? They've already got a microwave gun to fry us if we get a little rowdy during a protest...why not just get a light gun to turn all our brains off simultaneously?

      --
      1 is the square root of all evil.
    5. Re:Who wants to bet... by Anonymous Coward · · Score: 0

      Fortunately, the light isn't recieved through the eyes. It's shone directly on the misbehaving cells.
      Otherwise, I feared for coma victims from online gaming ;P. Whew, that is definitely one part of .hack// I DON'T want to see becoming reality @_@.

  3. Finally! by Steve--Balllmer · · Score: 5, Funny

    ... a scientific reason why we /.ers should not leave the darkness of our parents' basements and our computer monitors, and continue to avoid the dreaded realm known as "outside".

    1. Re:Finally! by Anonymous Coward · · Score: 0

      So you think there is that thing called "outside"?

    2. Re:Finally! by Anonymous Coward · · Score: 0

      There has to be something there because the boy who pushes the pizza through the basement window says so.

    3. Re:Finally! by Anonymous Coward · · Score: 0

      This also explains why "jock" types constantly wear baseball caps. They are trying to protect what little brain power they have.

    4. Re:Finally! by jeffeb3 · · Score: 1

      I don't think you are a typical /.er. Most of us find a way to make it to McDonalds.

    5. Re:Finally! by RxScram · · Score: 1

      I think most of us have pizza delivered.

    6. Re:Finally! by grammar+fascist · · Score: 2, Informative

      ... a scientific reason why we /.ers should not leave the darkness of our parents' basements and our computer monitors, and continue to avoid the dreaded realm known as "outside".

      You mean that big, blue room?

      I dunno about you, but I have problems going in there in the first place. That room is big. And it's got that huge, moving light that radiates heat. Probably, what, 1000 watts? Boggles the mind.
      --
      I got my Linux laptop at System76.
    7. Re:Finally! by tanguyr · · Score: 1
      --
      #!/usr/bin/english
    8. Re:Finally! by StarfishOne · · Score: 1

      And have you seen the textures used in that huge outside room? They're sooooo realistic. And sometimes the polygon count is absolutely extreme, especially in busy shopping malls.

      Be advised to have multiple shaders, the latest hardware acceleration and good cooling before going to that place!

    9. Re:Finally! by NeilTheStupidHead · · Score: 1

      But the controls are so non-intuitive!

      --
      Lose: misplace or fail || Loose: not bound together
  4. Slight problem with their idea... by Anonymous Coward · · Score: 5, Insightful
    According to the article:

    When neurons are engineered to express the halorhodopsin gene, the researchers can inhibit their activity by shining yellow light on them. Light activates the chloride pumps, which drive chloride ions into the neurons, lowering their voltage and silencing their firing. So, if we genetically engineer some people with Parkinson's or epilepsy to have these halorhodopsin neurons, we can give them a normal life as long as we find a way to shine light directly into their brains?
    1. Re:Slight problem with their idea... by mrbluze · · Score: 3, Insightful

      So, if we genetically engineer some people with Parkinson's or epilepsy to have these halorhodopsin neurons, we can give them a normal life as long as we find a way to shine light directly into their brains?

      I think the article infers that we genetically engineer animals with Parkinson's and Epilepsy having the gene (that is, set up a disease model), then implant LED's into their heads, play with the lights and see what happens, then get a PhD and maybe even a Nobel Prize.

      It's unlikely they would use this method in actual human therapy.

      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    2. Re:Slight problem with their idea... by Anonymous Coward · · Score: 0

      So, if we genetically engineer some people with Parkinson's or epilepsy to have these halorhodopsin neurons, we can give them a normal life as long as we find a way to shine light directly into their brains?


      Wait! It's better. This person who's a little brain-fried from parkinsons or epilepsy shows up for a treatment/fitness consultation, and the doctor says, "Well, there's two choices, really. We can go with a massive jolt of electricity, or we can fire off a big-ass flashlamp in your brain! Which way do you want to go?"
    3. Re:Slight problem with their idea... by Anonymous Coward · · Score: 1, Informative

      The talk in the article of using this technique to help patients with various diseases is just hype to keep the funding bodies happy. Life science grants in the States have been cut substantially becauses of Bush's war-mongering and there's a scramble for cash. On the other hand, the technique is very interesting for pure neuroscience research because we now have a way of using light to rapidly and very selectively switch activity on and off in a brain slice. Up to this point we've had to either bathe the whole slice in a substance that alters activity or to apply it through a pippette to the region of interest. The latter method is obviously better but requires careful application and the substance may need to be washed out before continuing the experiment. Using light allows us to control activity like a switch and by focusing the signal we'd be able to stimulate or inhibit (multiple?) regions of whatever size we saw fit. This is damn exciting stuff.

    4. Re:Slight problem with their idea... by Anonymous Coward · · Score: 0

      OK, now the breakthrough is made, it's time to make plan to put this discovery to good use.

      Basically, from TFA, it boils down to following sequence of simple steps:

      1. Invent a method to find out who...which human zygote will develop Parkinson's in later life.
      2. recombine its DNA to introduce halorhodopsin gene (2.a. find out where to insert it)
      3. embed the zygote back into placenta.
      4. after the gestation and birth, wait 40-60 years for illness to develop
      5. surgically open the scull of the patient, or drill holes at selected points of it
      6. shed the yellow light on the brain
      7. Profit!

    5. Re:Slight problem with their idea... by mrogers · · Score: 2, Interesting

      It might be possible to use retroviruses to insert the light-sensitive genes into the patients' cells.

    6. Re:Slight problem with their idea... by kripkenstein · · Score: 4, Insightful
      No, actually the article directly implies that human treatment will come out of this:

      "In the future, controlling the activity patterns of neurons may enable very specific treatments for neurological and psychiatric diseases, with few or no side effects," said Edward Boyden, assistant professor
      - so this is not just a case of a bad writeup of serious research, or a bad summary on Slashdot. It could be a quote taken out of context, though. In any case, the researchers think this (or something related to it) will be viable eventually, while I, for one, must agree with the grandparent post - how exactly will these light-sensitive chloride pumps get into the brains of already-living sick people?

      I assume that the final human treatment, if any is arrived at, will be very different from what they are doing at present. Time will tell. In any case, a very interesting area of research, even if it is hyped a little regarding possible applications.
    7. Re:Slight problem with their idea... by mrbluze · · Score: 1

      - so this is not just a case of a bad writeup of serious research, or a bad summary on Slashdot.

      Indeed you're right, but I'm just a bit skeptical about gene therapies for this kind of thing - but anything is possible, right?

      Chloride channels, when opened, generally inhibit brain activity. This is the basis of anaesthetic agents, by and large, and the treatment for acute epileptic seizures. The problem is that the brain reuses the same channel types everywhere, and it's frightfully hard to get targeted drug therapies. If, on the other hand, we could get drugs into the body which are otherwise inactive, but become activated when exposed to the light source, then this would allow extremely targeted therapy - not just with treating epilepsy or parkinson's disease, but for isolated tumour masses. But I still don't think that this is what they were thinking of in the write up.

      No, actually the article directly implies that human treatment will come out of this:

      Practically all animal medical research is directed towards solving human health problems, so I implied that also - just I think it will be less direct. The probable outcome from this research will be both surgical and pharmacological, I'm sure, but I don't think we'll be putting lights into people's heads any time soon, at least not for this purpose.

      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    8. Re:Slight problem with their idea... by Chris+whatever · · Score: 1

      Always wanted to look like the game Lite-brite

    9. Re:Slight problem with their idea... by ijakings · · Score: 1, Funny

      Oh dear, you violated one of the most sacred of all troll posts. How can you profit sequence without the ???'s?! its the ??? that makes it funny. Observe: 1) Invent a device to stab trolls in the face through the internet 2) ??? 3) Profit! Its just that easy.

    10. Re:Slight problem with their idea... by milamber3 · · Score: 1

      I suppose, seeing how they are scientists and all, that they could be looking forward to progress made in the realm of gene therapy to deliver the chloride pumps to the target neurons. Receptors in neurons are constantly turning over, so adding the gene for the pump would be a viable way to express it. I would have hoped the slashdot crowd would be take a little time and think about the future implications possible with this study rather than condemn it as non-feasible.

    11. Re:Slight problem with their idea... by osgeek · · Score: 1

      Exactly what I thought as I was reading the article. It's one thing to have a little sensationalism in article title summaries to spice things up a bit; but to say that researches stop brain activity with light and that this technique could be used to help with people with epilepsy is just downright wrong.

      Articles summaries like this need to be pulled and rewritten or discarded. I find it really annoying to be dealt a bait and switch by Slashdot.

    12. Re:Slight problem with their idea... by bkr1_2k · · Score: 1

      Well in some cases of epilepsy light can already trigger an attack, so it could be possible the "faulty" neurons already have something which will allow use of light without creating any chloride pumps.

      I know nothing about it though, so that's purely speculative. The article did put a nice big "give us more money" spin on things didn't it. I was also intrigued that they published in an online journal "Public Library of Science One" rather than a more recognized journal. To me that automatically implies their work isn't up to peer scrutiny, but again, that's a biased impression.

      --
      "Growing old is inevitable; growing up is optional."
    13. Re:Slight problem with their idea... by hey! · · Score: 1

      how exactly will these light-sensitive chloride pumps get into the brains of already-living sick people?


      Severe forms of these diseases have been treated by severing the hemispheres of the brain from each other or even removing large chunks of the brain. If the disease is so bad that those therapies aren't considered worse, there's practically a universe of invasive surgery that'd be worth considering.
      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    14. Re:Slight problem with their idea... by superbrose · · Score: 1

      how exactly will these light-sensitive chloride pumps get into the brains of already-living sick people?
      1. Find a volunteer.
      2. Using a surgical saw, cut LED sized holes into the skull and carefully remove the cut out bits. (At this stage the skull will look similar just like a colander.)
      3. Insert LEDs into desired positions, leaving the connective wires hanging out of the holes in the skull.
      4. Attach tiny solar panels which fit snuggly into the LED-sized holes in the skull.
      5. Make sure patient does not enter unlit surroundings, and equip with backup torch.
      Voilà.
    15. Re:Slight problem with their idea... by Anonymous Coward · · Score: 0

      Actually, it was not intended to be funny (or troll), just got carried with the flow on that last one... The point is that the stated effect may require planning too long ahead and significant changes in the patient... well, if we could do that, the obvious solution would be to use GE to outright make patient not prone to epilepsy or Parkinson's instead of introducing "curability". Overall, their work is very interesting and significant for further research (controlled experiments on lab animals in vivo) although clinically impractical. In short, misleading title!

    16. Re:Slight problem with their idea... by mcpkaaos · · Score: 1

      how exactly will these light-sensitive chloride pumps get into the brains of already-living sick people?

      It's still early, but I hear they are also working on an automated delivery system

      --
      It goes from God, to Jerry, to me.
    17. Re:Slight problem with their idea... by Molochi · · Score: 1

      There's a Boston joke here somewhere. I guess you'd be safe as long as you stayed on the Cambridge side of the river.

      --
      "The Adobe Updater must update itself before it can check for updates. Would you like to update the Adobe Updater now?"
    18. Re:Slight problem with their idea... by robotkid · · Score: 1

      Bingo, that's exactly right. While I do agree that this is an extremely clever approach, it has the same Achilles heel as any other genetic treatment, i.e. the lack of any viable, working delivery system. Putting in new genetic material typically involves some sort of stem-cell graft for regenerative tissues (i.e. bone marrow) or some sort of modified virus delivery system. Since neurons don't regenerate, that leaves option 2 (directly injecting a virus into the brain) which is, well, a pretty bad idea right now considering the disasters that have occured in most gene therapy trials to date.

      The bright side is, if a safe and effective delivery system were invented, you wouldn't need to worry as much about delivery to non-target tissues (i.e. the neurons that are working perfectly) since a doctor could reversibly choose and optimize which specific areas to shut down, they way they do now with impanted electrodes for Parkingson's patients.

    19. Re:Slight problem with their idea... by garnetlion · · Score: 1

      That description, while funny, made my skull hurt.

  5. does it come in an ale? by User+956 · · Score: 4, Funny

    The MIT home-page story today is about a way to use light to shut down brain activity.

    Well, I guess that's cheaper than alcohol.

    --
    The theory of relativity doesn't work right in Arkansas.
    1. Re:does it come in an ale? by Anonymous Coward · · Score: 0

      It'd be a horribly lite brew.

    2. Re:does it come in an ale? by untouchableForce · · Score: 1

      Are you kidding me, do you know what the patent royalties will be for this. They'll probably charge you per lumen. On the bright side at least the RIAA doesn't have anything to do with it. They would charge you per lumen with an extra fee for every thought you had for the remainder of your life. And we won't even get into what would happen if you share one of those thoughts.

      --
      Moderation is not supposed to be used as an indicator of agreement.
    3. Re:does it come in an ale? by spikedvodka · · Score: 1

      The MIT home-page story today is about a way to use light to shut down brain activity.

      Well, I guess that's cheaper than alcohol.

      Simon (BOFH) already has a method for shutting down someone's brain activity

      It's called "Boss-Mode" Simply start talking in Level-10 Geek-speak, and watch the Boss's brain shut down

      --
      I will not give in to the terrorists. I will not become fearful.
  6. Politics by nagora · · Score: 5, Funny

    Expect to see a lot of yellow lights at party rallies from now on...

    --
    "Encyclopedia" is to "Wikipedia" what "Library" is to "Some people at a bus stop"
    1. Re:Politics by hazem · · Score: 1

      There are FOUR lights!

    2. Re:Politics by sckeener · · Score: 1

      Expect to see a lot of yellow lights at party rallies from now on...

      yellow lights
      I never wanted to vote for the lesser of two evils anyway....

      Vote Cthulhu!

      --
      "Only one thing, is impossible for god: to find any sense in any copyright law on the planet." Mark Twain
  7. Makes sense by gaderael · · Score: 2, Funny

    Considering certain patterns of light, as found in some video games, for example, have the ability to bring about seizures and people the suffer from Epilepsy, it makes sanse that certain patterns of light would also be able to reverse that effect.

    --
    Anyone got a light for my sig?
    1. Re:Makes sense by bindo · · Score: 4, Insightful

      Considering certain patterns of light, as found in some video games, for example, have the ability to bring about seizures and people the suffer from Epilepsy, it makes sanse that certain patterns of light would also be able to reverse that effect.

      Considering certain patterns of falling boulders, as found on some mountains, for example, have the ability to bring death and people the suffer from Epilepsy (sic!). it makes sanse that certain patterns of falling boulders would also be able to reverse that effect.
      NOT!

      Common sense is not a substitute for knowledge. The two effects are not even related.

    2. Re:Makes sense by MichaelSmith · · Score: 1

      Considering certain patterns of light, as found in some video games, for example, have the ability to bring about seizures and people the suffer from Epilepsy, it makes sanse that certain patterns of light would also be able to reverse that effect.

      No, thats what happens when pulses of light generate signals in the brain via the optic nerve which interfere with existing signals in the brain. Incidently, back when people used to build strobe lights for discos, etc there used to be warnings about pulsing lights at certain frequencies.

      Now we seem to regard bicycle tail lights which pulse at 12Hz as a good thing. I am not sure that I agree.

    3. Re:Makes sense by Lorkki · · Score: 1

      I'm not sure if common sense is a proper name for that, it sounds more like weird cartoon logic to me.

    4. Re:Makes sense by Anonymous Coward · · Score: 0

      That explains the feeling of an upcoming seizure when i see patterns arranged in the form of a windows logo. It's reversed when I see either a penguin or an apple.

    5. Re:Makes sense by Shrubber · · Score: 3, Funny

      Considering certain patterns of falling boulders, as found on some mountains, for example, have the ability to bring death and people the suffer from Epilepsy (sic!). it makes sanse that certain patterns of falling boulders would also be able to reverse that effect.
      Obviously. It's already been proven in cartoons time and time again that if something falling on your head causes amnesia or a personality change that additional impact to your head will cure it. In the case of personality change you may need to apply such force several times as you may simply trigger alternate personalities instead, but you can repeat until satisfied.
    6. Re:Makes sense by SatanicPuppy · · Score: 1

      It's the Fallacy of the Irrelevant Conclusion.

      Basically you're saying:

      If B then A (If Light causes epileptic fits, then video games will cause epileptic fits)
      If D then C (If Light can shut down cells that cause epileptic fits, then light can cure epilepsy )

      Therefore If B then C (If light can cause epilepsy, light can cure epilepsy).

      Clearly doesn't follow. It's like saying, "If arsenic can cause death, then arsenic should be able to cure death."

      --
      ad logicam Claiming a proposition is false because it was presented as the conclusion of a fallacious argument.
    7. Re:Makes sense by TheObruniSpeaks · · Score: 1

      Actually, the yellow light (and blue light mentioned for stimulation) is targeted directly onto the neurons... It is not shined on the eyes and processed by the visual systems, so the two effects are unrelated.

    8. Re:Makes sense by RobertLTux · · Score: 1

      Clearly doesn't follow. It's like saying, "If arsenic can cause death, then arsenic should be able to cure death."

      umm you shot your little toe off with that statement since proper dosage and need is what you have to consider

      a heck of a lot of older drugs are bits of plants/things that in dose X per POBW cures (condition) but dose NX is fatal
      drink a cup of willow bark tea and cure a headache drink a half barrel of Willow bark tea and you could be coughing up your stomach --raw aspirin is in WBT
      Belladona is another one half a leaf and you keep your ticker going half the plant and its Buh BYE time

      a lot of drug production is making the dif between therapeutic dose and LD50 very very wide (and not needing to use 8 tons of plant to make 4 bottles of drug)

      --
      Any person using FTFY or editing my postings agrees to a US$50.00 charge
    9. Re:Makes sense by SatanicPuppy · · Score: 1

      I don't mean, "Arsenic has no beneficial uses." I mean, literally, "Arsenic can't bring you back from the dead." Arsenic can cause death when applied to a living person. When applied to a dead person it can't cause life.

      My statement was a bit ambiguous, I apologize.

      --
      ad logicam Claiming a proposition is false because it was presented as the conclusion of a fallacious argument.
    10. Re:Makes sense by moeinvt · · Score: 1

      I'm surprised by your total dismissal of the idea. ? First of all, I think the "video games" portion was just an example. That aside,

      It's absolutely true that using pulsing lights in particular ways can stimulate epileptic seizures. Doctors often do this during an EEG so that they can map the brain activity of the patient during the seizure. If lights can be used to stimulate neuron activity, the idea that light might be used to inhibit neuron activity doesn't seem like that much of a stretch, at least to me.

      I realize that TFA is talking about exposing brain tissue directly to light, but I'm curious as to why you're so vehement in thinking that shining lights in the eyes could not have some sort of dampening effect on seizure activity?

    11. Re:Makes sense by fireboy1919 · · Score: 1

      In the case of personality change you may need to apply such force several times as you may simply trigger alternate personalities instead, but you can repeat until satisfied.

      This is a well understood phenomenon.

      --
      Mod me down and I will become more powerful than you can possibly imagine!
    12. Re:Makes sense by donscarletti · · Score: 1

      Arsenic can be used for embalming and is very useful to make dead people look living, there's a corpse of a little girl in Sicily that still looks like she is alive 200 years after her death due to arsenic. It's not really the same thing of course but it is fascinating.

      --
      When Argumentum ad Hominem falls short, try Argumentum ad Matrem
  8. Turning Lights on in Young Minds by Anonymous Coward · · Score: 0

    Just gained a new and potentially scarier meaning. What you bet that if this goes anywhere that ADHD is next on the list and the teacher gets a remote control?

  9. I know this technique by Anonymous Coward · · Score: 1, Funny

    It's called Family Vacation Slideshow.

  10. Sounds like The Prisoner is coming to life! by Tribbles · · Score: 1

    As in the '60s British series - they had lights that pulsed over peoples faces to make them do/forget things...

  11. Hooray! by mikkelm · · Score: 5, Funny

    Finally I can get a pair of tinfoil shades to go with my hat.

    1. Re:Hooray! by Anonymous Coward · · Score: 0

      Related:

      >
      > "The research was funded by an anonymous donor [...]"
      >

      We sure all wonder who is this "anonymous donor".

      >
      > "The technique also offers a way to study other brain
      > diseases, as well as normal brain circuitry, offering
      > insight into which brain regions and neurons contribute
      > to specific behaviors or pathological states, Boyden said."
      >

      It could indeed be useful, for pathological states like wanting more freedom, more privacy, more reasonability, and less stress, less oppression, less frustration, etc., and worst of all, acting on these desires.

      *Ahhh*.... just who might be this "anonymous donor"...

    2. Re:Hooray! by rolfc · · Score: 1

      Maybe it is an Anonymous Coward?

    3. Re:Hooray! by GodfatherofSoul · · Score: 1

      I know where you can find a pair.

      --
      I swear to God...I swear to God! That is NOT how you treat your human!
  12. is it a tv? by Anonymous Coward · · Score: 1, Funny

    otherwise known as a boobtube....

  13. Or Wolfe by CRCulver · · Score: 1

    Gene Wolfe's The Book of the Long Sun had computer monitors could implant an artificial intelligence in anyone who looked at their patterns of swirling colours (as the population in the novels worshipped these artificial intelligences, this was seen as "possession by a god" like in ancient Greek thought). Ironically, this has been called by some critics the most scientifically unbelievable thing in the work, since "looking at patterns of light can't change your brain."

    1. Re:Or Wolfe by cnettel · · Score: 4, Informative

      This is direct exposure, not through the eyes. In addition, the neurons have been altered (an added gene with a photosensitive product) to respond to this treatment.

    2. Re:Or Wolfe by dutin · · Score: 1

      Ironically, this has been called by some critics the most scientifically unbelievable thing in the work, since "looking at patterns of light can't change your brain."

      Have you ever seen anyone who doesn't watch television get cable? It indeed changes your brain.
    3. Re:Or Wolfe by Gryffin · · Score: 1

      This is direct exposure, not through the eyes.

      Good point.

      But there's a lot of "prior art" that shows you can achieve the same effect through the retina with a bluish light... specifically, that from a television.

      --
      Learn from the mistakes of others. You won't live long enough to make them all yourself.
  14. Hmmm, sounds strangely familiar by Slugster · · Score: 1

    Any of you young'uns old enough to remember the movie Looker?
    http://www.imdb.com/title/tt0082677/
    ....
    Hmmmm,,,
    Holy shit! They're two for two-- CGI media models, and now this. Maybe I better go back and watch that movie again....
    ~


    (-by the by, I'd still like to find the soundtrack to this movie, if anyone has run across a copy-)

    1. Re:Hmmm, sounds strangely familiar by HTH+NE1 · · Score: 1

      Any of you young'uns old enough to remember the movie Looker?
      Indeed, it was my first thought.

      (-by the by, I'd still like to find the soundtrack to this movie, if anyone has run across a copy-)
      I don't know about the soundtrack (possibility, but not enough information to identify), but the movie is out on DVD (and at a cheaper price elsewhere).
      --
      Oh, say does that Star-Spangled Banner entwine / The myrtle of Venus with Bacchus's vine?
    2. Re:Hmmm, sounds strangely familiar by Chruisan · · Score: 1

      Thanks. I couldn't remember the name of that movie.

  15. I, for one... by bwd234 · · Score: 3, Funny

    welcome our new yellow light emitting overlords!

    1. Re:I, for one... by Anonymous Coward · · Score: 0

      What exactly did this +4 Informative post inform us of? Am I missing something here?

    2. Re:I, for one... by bwd234 · · Score: 1

      I, for one, don't get it either. :)

  16. Damn yellowish incandescents. by SeaFox · · Score: 2, Funny

    Scientists at the MIT Media Lab have invented a way to reversibly silence brain cells using pulses of yellow light

    Yet another reason CFLs are better!
  17. Another ,,, by BlueTrin · · Score: 5, Funny

    Another sexist topic about blonde girls !

    --
    Don't you know it is now both immoral and criminal to think beyond the next quarterly report?
  18. Military use by jlebrech · · Score: 0

    Think of what could happen if that kind of technology is use to make a weapon!

    1. Re:Military use by toQDuj · · Score: 1

      Yea! they could get bullets that penetrate the skull, and then shine a yellow light on the brain! Oh wait...

      B.

      --
      Every experiment which ends in a big bang is a good experiment.
  19. Requires halorhodopsin gene by sshore · · Score: 5, Interesting

    According to the article, the yellow light "silences" neurons that have been engineered to include the halorhodopsin gene found in certain bacteria. The light doesn't have the same effect on the neurons that you'd typically find in your skull.

    I'm not sure how this would be used clinically to treat epilepsy. Perhaps by introducing the genes into cells in the affected area using a retrovirus?

    1. Re:Requires halorhodopsin gene by MichaelSmith · · Score: 1

      Perhaps by introducing the genes into cells in the affected area using a retrovirus?

      If you could do that then you could do lots of other useful things. How about engineering neurons to emit photons in the presence of an electric field and using the resulting stream of photons to model thought processes?

    2. Re:Requires halorhodopsin gene by The_mad_linguist · · Score: 1

      So then their heads would look like Data's, eh?

    3. Re:Requires halorhodopsin gene by prelelat · · Score: 1

      I'm not sure about epilepsy, but i believe there has been some research that shows a link between parkinsons and genetics. Not that you will get it for sure but that you are more likely to get it because you were exposed to certain drugs or enviroment. If these genes are found in someone early maybe they could add the mutated gene to them so that if they do start showing signs of parkinsons they can be treated.

      I would think a better cure would be to fix the nerological problems or stop them from degrading futher once they are discovered.

      I don't know much about genetics or biochemistry though. This is stuff I just speculate because I like to.

    4. Re:Requires halorhodopsin gene by Dread_ed · · Score: 1

      "Perhaps by introducing the genes into cells in the affected area using a retrovirus?"

      Ya, and in exchange for your epilepsy relief (dubious) you get brain cancer. For those ready to commit suicide from the effects of debilitating epilepsy this might be a more painful and degrading way to go.

      Besides, if you could use a retrovirus to introduce a snipped of DNA and then use that DNA to treat the symptom, why not use a retrovirus to treat the cause directly. That way you only have side effects from one phase treatment. Otherwise you have side effects from the retrovirus, the surgery to implant the lights, and the actual light treatment when it is used.

      As someone who lives with epilepsy on a daily basis I think that this will fall into the category of interesting medical minutae. Whether or not scientists say that this is effective in treatment of humans is irrelevant (they have to say that to get more funding.) The tech needed to get this on the field of battle will make it obsolete.

      --
      When the only tool you have is a claw hammer every problem starts to look like the back of someone's skull.
    5. Re:Requires halorhodopsin gene by TheSync · · Score: 2, Interesting

      There has already been an example of successful gene therapy with retroviruses, and no they didn't get caner, they were cured of cancer.

      However the blood-brain barrier is a limitation to brain gene therapy. So in 2003 a UCLA research team inserted genes into the brain using liposomes coated in polyethylene glycol.

  20. Yellow light? by durin · · Score: 1


    As in sunlight?

    I think they should take a look outside for once.

    --
    Why, yes! I AM new here.
    1. Re:Yellow light? by Anonymous Coward · · Score: 0

      Actually, believe it or not, sunlight is blue. Incandescent bulbs are yellow, and Fluorescent bulbs are green.

    2. Re:Yellow light? by solevita · · Score: 1

      Not to mention the fact that most people don't have holes in their head through which sunlight could enter. Although in the case of the OP, I'm not so sure.

    3. Re:Yellow light? by Goaway · · Score: 2, Informative

      As far as it is possible to make any kind of statement about this, sunlight is white.

    4. Re:Yellow light? by Anonymous Coward · · Score: 0

      "As far as it is possible to make any kind of statement about this, sunlight is white."

      What the hell? You can say a whole lot more than that. For instance, check out a good astronomy textbook and you'll find a spectrum of sunlight.

    5. Re:Yellow light? by Goaway · · Score: 0, Flamebait

      I know the spectrum of sunlight very well, thank you. A spectrum is not the same as a colour. A colour is something that only exists as a subjectively preceived sensation.

      And the closest we can get to saying anything about the colour of sunlight is that we preceive it as white.

  21. Bright guys by Anonymous Coward · · Score: 0

    Aah, that's why the bright guys seem so stupid at times...

  22. Bah, too slow by GFree · · Score: 1

    There are quicker ways to shut down the brain.

    Playing 'Russian Roulette' with a semi-automatic pistol is one idea.

  23. Useless by Anonymous Coward · · Score: 0

    I don't see the point here. Shutting down light with brain would be more useful. And making it work with TV would be the must !

  24. Test subjects by Anonymous Coward · · Score: 0

    Maybe they could test this on the politicians in the US to see if it does work.
    Actually This might not show as any difference!

  25. It's about brain implants for research purposes by mrbluze · · Score: 3, Insightful

    Did anyone read TFA? It has nothing to do with light entering the eye and hitting the retina. Forget the strobe lights!

    This study is great, because it means we can study animals better. It means researchers will get much more useful information from animal studies (instead of operating on 1000's of rabbits or something, they can do heaps of studies on just one rabbit), which will lead to new and better targets for drug research, better drugs, and perhaps a cure - way down the track.

    --
    Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    1. Re:It's about brain implants for research purposes by ogma · · Score: 3, Funny

      "This study is great ... instead of operating on 1000's of rabbits ... they can do heaps of studies on just one rabbit"

      Unless you're that one rabbit!

    2. Re:It's about brain implants for research purposes by bobscealy · · Score: 4, Funny

      Did anyone read TFA?



      You ain't from round here, are you boy?

    3. Re:It's about brain implants for research purposes by mrogers · · Score: 1

      You can't do a series of experiments on the same animal, because the effects of previous experiments could interfere with the current experiment. Animals are usually "sacrificed" after one experiment because they're no longer useful from a statistical point of view, regardless of whether it's physically possible to perform further experiments on them.

    4. Re:It's about brain implants for research purposes by tgv · · Score: 1

      Did any read it? You might better ask: did anyone understand it? Because that doesn't seem to be necessary to get +5 insightful for you comments.

      About the interference from previous experiments within the same animal: it depends on what you want to investigate. Of course there is neural adaptation, but in most regions it is quite slow. So after one experiment you might let the animal run around under normal conditions and it'll be as ready as ever, if only for another experiment.

      Plus, when you're able to suppress unrelated activity, you might get a much cleaner signal and thus need less animals.

    5. Re:It's about brain implants for research purposes by roman_mir · · Score: 1

      It means researchers will get much more useful information from animal studies (instead of operating on 1000's of rabbits or something, they can do heaps of studies on just one rabbit) - listen, I am all for studying rabbits and all, but if that one rabbit gets pissed off, I wouldn't want to be responsible for the safety of those researchers. If they really want to learn how far they can push a rabbit before it turns into a green monster rabbit and eats their brains out, they can go right ahead.

    6. Re:It's about brain implants for research purposes by LynnwoodRooster · · Score: 1
      Did anyone read TFA? It has nothing to do with light entering the eye and hitting the retina. Forget the strobe lights!

      Clearly your strobe light isn't strong enough... I suggest you upgrade a bit...

      --
      Browsing at +1 - no ACs, I ignore their posts. So refreshing!
    7. Re:It's about brain implants for research purposes by mrbluze · · Score: 1

      Clearly your strobe light isn't strong enough... I suggest you upgrade a bit... Ha! good one! I think that does throw some more light on the issue! That link should be submitted, man!
      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
  26. Tin foil glasses by Eudial · · Score: 1, Funny

    Think of the applications! Time to get a pair of them tin foil glasses to accompany the hat.

    --
    GAAH! MY PRINTER IS ON FIRE!!! PUT IT OUT! PUT IT OUT!
  27. But can it... by Anonymous Coward · · Score: 0

    Finally help me get to sleep regularly?!? Please!!

  28. Hal Jordan unavailable for comment... by Anonymous Coward · · Score: 1, Funny

    Can't believe you missed the follow up article:

    OA (Reuters) - The Guardians of the Universe held a press conference today after scientists in the MIT Media Lab announced that neural activity could be suppressed through the usage of yellow light.

    Spokesperson Tom Kalmaku stated, "It's charming to see that the scientists in Sector 2814 have finally caught on to something the rest of the Galaxy has known for the better part of the past three billion years. The Corps have had to deal with the effects of yellow light since it's inception. It's a very powerful frequency in the spectrum and is difficult to counteract."

    Oa's Central Power Battery has been vulnerable to the effects of yellow for some time now and the Guardians have no means of defending against it. "In the past, we tried dipping the thing in a thin, transparent blue polymer once but it didn't seem to help any." said Kilowog when prompted on the subject.

    MIT is very pleased with the discovery, but currently has no means available to implement this to the benefit of epileptics and Michael J. Fox.

    Additionally, an anonymous follower of Dinshah P. Ghadiali's alternative Color Therapy medical techniques was also unimpressed by the news and simply stated, "Colored light? Effect the body? Duh!"

    When contacted for comment, Hal Jordan was unavailable.

  29. Re:Rule 34 challenge by DamienNightbane · · Score: 0, Offtopic

    DO NOT WANT

  30. Like MIB by Warg!+The+Orcs!! · · Score: 1

    nothing was seen here, move along..

    --
    Travelling forward in time at a rate of 1 second per second.
  31. I've seen this in real life by Centurix · · Score: 1

    Shining sunlight on my mother-in-law makes her melt into a puddle on the floor...

    *ba-dum-tish*

    Wait, there's more, take my mother-in-law, please.

    --
    Task Mangler
  32. Obligatory by Dragon+By+Proxy · · Score: 1

    "I felt a great disturbance in the Force, as if millions of voices suddenly cried out in terror and were suddenly silenced."

  33. Misuse by kraemate · · Score: 1

    I think this is a great achievement. But what about it's misuse%)+!@% NO PULSE

  34. belonging by Stooshie · · Score: 2, Funny

    All your neuron are belong to us!

    --
    America, Home of the Brave. ... .and the Squaw.
  35. Three memes in one, whee by FirienFirien · · Score: 1

    So to disable the frikkin sharks with lasers, we just have to reverse the polarity of the flux capacitors?!

    --
    Browsing with +2 to insightful posts and a higher threshold makes the average post seen seem a lot more ingenious
  36. My mother-in-law....... by OneSmartFellow · · Score: 1

    .......what a man !

  37. Great! by John+Betonschaar · · Score: 3, Insightful

    Now all we need is a different type of light to activate some people's brains!

    1. Re:Great! by d3m0nCr4t · · Score: 1

      Yes, I agree, but before you can activate the brain, some are going to need a brain.

    2. Re:Great! by TheObruniSpeaks · · Score: 1

      That's what blue light and channelrhodopsin is for! I think it might be mentioned in TFA... If not, well, it's the exact same idea, only instead of hyperpolarizing like yellow light+halo, it depolarizes and causes action potentials to fire, which is activating the neuron.

      Although, bear in mind that *not* firing is saying something to the brain, just like firing says something else to the brain. "Active" vs. "inactive" isn't always the way to think about it. The function of huge numbers of interneurons is to inhibit other neurons from firing!

  38. If yellow light shuts down brain cells... by SethHoyt · · Score: 5, Funny

    Could this explain why when a traffic light turns yellow, nobody seems to notice it?

    1. Re:If yellow light shuts down brain cells... by hyfe · · Score: 1
      If god wanted us to obey traffic lights, he would have written about it in the bible.

      The traffic lights are not my gods!

      --
      "" How about taking the safety labels off everything, and let the stupidity-problem solve itself? """
  39. well, by porl · · Score: 1

    i can think of one...

  40. We already knew this by TomatoMan · · Score: 3, Funny

    TV has been shutting all of our brains down for decades.

    --
    -- http://frobnosticate.com
    1. Re:We already knew this by A_Non_Moose · · Score: 1

      TV has been shutting all of our brains down for decades.


      Nah, TV just lowers it and/or slows it down.

      Powerpoint, on the other hand has been doing it for years, on *both* sides of the projector.

      Can't really use the acronym for Powerpoint Meeting Syndrome...it's take for some reason.
      --
      Have you read the moderator guidelines? Well, have you, PUNK? (and I want a Karma: Gnarly option)
  41. Not new by Graywolf · · Score: 1

    I thought Hollywood had invented a way to shut down brains using light (and sound) a long time ago...

  42. I read that wrong by goraknotsteve · · Score: 1

    After seeing the link on my RSS feed I wondered what MIT had against Brian and why they wanted to shut him down... Just as well I've read the article now

    --
    How much do you like toast?
  43. Everything is clear now by octogen · · Score: 1

    Now I know why all these other guys are driving around like braindead morons in their cars. Maybe I should stop using INDICATOR LIGHTS...
    ROFL

  44. All that glitters by abb3w · · Score: 1, Interesting

    So, does this also help explain the strange allure of gold throughout history, and the use of gold for religious ornamentation?

    --
    //Information does not want to be free; it wants to breed.
    1. Re:All that glitters by Anonymous Coward · · Score: 0

      No.

    2. Re:All that glitters by Anonymous Coward · · Score: 0

      Yes, and it also explains the allure of rubies, emeralds, and sapphires. Or not.

    3. Re:All that glitters by Kingrames · · Score: 1

      doubtful. Similar arguments could be made for any other color, as valuable gems come in all the shades of the rainbow.

      --
      If you can read this, I forgot to post anonymously.
    4. Re:All that glitters by StikyPad · · Score: 1

      Yes. It also explains the strange allure of sulfur, safety vests, and urine, which in turn explains the allure of the Villiage People.

  45. No news to me by Big+Nothing · · Score: 1

    This is no news to me. The same thing happens when the light at the office hits my eyes every morning. Almost 0 brain activity.

    --
    SIG: TAKE OFF EVERY 'CAPTAIN'!!
  46. Old news! by OriginalArlen · · Score: 1

    John Carpenter already demonstrated how to shut down brains with light. You just need a shaky grasp of metaphysics, and a very big bomb...

    --

    Everything I needed to know about life, I learnt from Blake's Seven
  47. Daggers of the Mind? by scovetta · · Score: 1

    I thought Kirk shut down this machine already.

    --
    Wer mit Ungeheuern kämpft, mag zusehn, dass er nicht dabei zum Ungeheuer wird. --Nietzsche
  48. Next: yellow lights in the Whitehouse & Congre by mnemotronic · · Score: 1
    Just think, shutting down the "brains" of the king and queens of america. As the article states:

    "...inhibition is more direct than excitation, because you can shut down neural circuits ..."
    Cool. We can turn off their brains. Turn them into mindless robots that pass the laws we want. They don't even have to be reasonable, or logical, or compassionate, just reactive religious zealots or irresponsible twits. Oh, wait. Somebody's already done it. damn.
    --
    The Russians have won. They have made the world a cesspool of distrust, greed, fear and hate.
  49. Going with... by DannyO152 · · Score: 1

    ... it's a cue to train elite surgical teams to take a Fantastic Voyage .

  50. With Light + *Genetic Engineering* by Doc+Ruby · · Score: 3, Informative

    When neurons are engineered to express the halorhodopsin gene, the researchers can inhibit their activity by shining yellow light on them.


    So not only would doctors have to get light inside the brain, they'd first have to genetically engineer the neurons to include and express the halorhodopsin gene. The right neurons: the ones that will later have Parkinson's Disease or whatever is being treated.

    How are they going to guess which neurons? Which healthy person is going to let them genetically engineer their neurons? Those neurons are going to behave the same, though they're now expressing proteins that make them work like retinal cells?

    Installing these shutdown hooks is a neat trick. But not for neurological medicine. Maybe for some biomechanics or biocomputation. Throwing genes into neurons for probing with light so violates our most absolutely personal spaces - inside our craniums and our genomes - that the cure is worse than the disease.
    --

    --
    make install -not war

    1. Re:With Light + *Genetic Engineering* by robotkid · · Score: 1

      So not only would doctors have to get light inside the brain, they'd first have to genetically engineer the neurons to include and express the halorhodopsin gene. The right neurons: the ones that will later have Parkinson's Disease or whatever is being treated.

      Right on about the bottleneck being the genetic engineering bit. But the whole advantage of the light-triggered shutdown is precisely that you could introduce it into an entire swath of neurons, and then only shut down the misfiring neurons (and you can reactivate them if you make a mistake by taking the light away). Otherwise, with a working gene delivery system, you could in principle just try to fix the faulty genes themselves - while bearing the risk of messing up already healthy cells.

      Existing treatments for Epilepsy are very invasive, involving open brain surgery, recording an actual seizure, and then burning out (irreversibly!) the neurons that start the seizure. If you burn the wrong place, or too large a spot, you could permanently alter brain functionality. Advanced Parkingsons treatment also involves implanting electrodes deep into the brain , except they use a small tunable electrode grid so that they can optimize/refine the area it is stimulating without repeated invasive surgeries.
  51. It's a wetware debugger. by TapeCutter · · Score: 3, Interesting

    I think the part about controling fits is very vaugue, I read "sponsor bait" or to be more polite speculation. Overall I think TFA gave the impression they are planning to use it to non-invasively investigate "circuits" in the hope of creating a device that can predict and prevent a fit with the minimum of intervention.

    The news (to me) in the story is a non-invasive tool that can "flip" individual neurons into a binary on/off state in a controlled manner. I don't know what current "tools" are capable of, nor their level of invasiveness, but it seems to me a wetware debbuging tool such as this could lead to an explosion of knowlage that would make it worthy of a Nobel prize in the not too distant future.

    Having said that, AFAIK indivdual neurons are not binary, their activity level is mesured as a "frequency". It would be interesting to know if the neuron's firing frequency can be controlled with more resolution than the simple on/off implied in TFA.

    --
    And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
    1. Re:It's a wetware debugger. by TheObruniSpeaks · · Score: 3, Insightful

      Yes, both the "on" (channelrhodopsin + blue light) and the "off" (halorhodopsin + yellow light) work on millisecond timescales, just like neurons normally do. The halo paper itself in PLoS one has a great image of being able to assassinate a single spike in a neuron being fired at a typical rate. You can also record a neuron's normal firing pattern and "play it back" with incredible fidelity using blue light to cause the firing.

    2. Re:It's a wetware debugger. by Plekto · · Score: 1

      It would be interesting to know if the neuron's firing frequency can be controlled with more resolution than the simple on/off implied in TFA.
      ****
      If they could do this, it would be the first step in building a device that would allow them to put information into your brain. ie - learning devices and so on. Maybe learning programs like we see in many science fiction movies someday will actually happen.

      It would be kind of nice to, say, learn a language without having to sit in a boring class for months and months. But it's of course going to be massively abused by governments around the world. Gives a new meaning to he idea of "sleeper agent".

    3. Re:It's a wetware debugger. by Coraon · · Score: 1

      I think they are planning this as a part of somekind of future nano theropy...but thats my guess

      --
      -Ours is the wisdom of Solomon, the magic of Merlyn, the fall of Icaris.
  52. I see it already by marcello_dl · · Score: 1

    In totally unrelated news, Microsoft corporation has announced a slight change of M$ Vista logo into an animated one, which will feature flashes of bright yellow. Anonymous sources at Microsoft explain the move as "one of the few options to improve Vista appeal"

    --
    ---- MISSING MISCELLANEOUS DATA SEGMENT --- [sigdash] trolololol
    1. Re:I see it already by Snick^ · · Score: 1

      thought it was the YSOD, kinda like BDOD but you won't notice.

  53. Trepanning by Anonymous Coward · · Score: 0

    "All right, to cure your wild movements, we're just going to drill a hole in your head to let the sunlight in. Don't worry, this is a standard medical procedure that has been used for thousands of years. All right, let's get them demons outta there!"

  54. TFA by thegnu · · Score: 1

    No, actually the article directly implies that human treatment will come out of this:

    You read the articles?!! What kind of sick fuck are you, anyway?

    On an actual point, though, Mr. Boyden just states that this SORT of thing could be used in The Future. Look: "In the future, controlling the activity patterns of neurons may enable very specific treatments for neurological and psychiatric diseases, with few or no side effects,"

    See? No mention of actually using what they're making. My girlfriend's a geologist, and she's constantly pissed off at the media's treatment and communication of scientific discovery, because it makes normal people believe things that aren't really true. That's where I learned how to read with discretion. Before I just indexed the words like Google, and gave word counts. ;-)

    --
    Please stop stalking me, bro.
  55. Matrix by javalizard · · Score: 1

    Welcome to the Matrix.

    How long will it take before they apply neural inhibition to the part of the brain that controls the mind-body interaction? Turn off the bodily links and you're in dream land. Control the dreams and you can create reality just like in the Matrix movies.

  56. So now... by Dunbal · · Score: 1

    Scientists at the MIT Media Lab have invented a way to reversibly silence brain cells using pulses of yellow light

          I wonder exactly how long this has been happening to president George W Bush, and is there any way to get his brain back?

    --
    Seven puppies were harmed during the making of this post.
  57. The best thing about this discovery... by s_p_oneil · · Score: 1

    ...is that they'd have to cut open your head to use it on you. Otherwise I'd be ready to go buy myself some tin foil to make a nice hat (and some very dark shades). I'm not into conspiracy theories, but some kinds of power people just shouldn't be allowed to have.

  58. Flashing lights by Delight-Delirium · · Score: 1

    'Fraid the kids at MIT are a little off. It's red and blue lights, and it explains why drivers on the highway come to a dead stop every time they see a car pulled over on the side of the road. Their brain activity stops. Of course!!!

  59. Damn you, Sinestro! by Ark · · Score: 1

    Yellow light stops brain activity? No brain activity, no will power. No will power, useless Green Lantern ring...

    So, even though the rings no longer have the "yellow impurity" Sinestro found a way to use yellow to stop the Green Lanterns. Someone call Hal, Jon, and Guy!

  60. Eh by TobyRush · · Score: 1

    We been doin' this for generations... ya shine yer flashlight right into the frog's eyes, ya see, and them frogs, they just sit there, starin' back at ya. Then ya pull out yer critter net out and bag em.

    Mmmm, good eatin, them frogs. 'Course it works with any varmint, but squirrel, that's lot tougher'n frogmeat. And bears, well, they's not too patient and less'n yer net's reeeeeal big...

    --
    Sam! If you will let me be,
    I will try them.
    You will see.
  61. MTV by jaywarrietto · · Score: 0

    am I the only one that first read that as MTV Shows How to Shut Down Brain With Light?

  62. Yellow Light? by njfuzzy · · Score: 1

    Yellow Light? Did that make anyone else wonder whether they are only experimenting on the Green Lantern?

    --
    My Photography - http://ian-x.com
    The Deathlings (comic) - http://thedeathlings.com
  63. Moo by Chacham · · Score: 1

    This is all fine bacterium.

    But can they run Linux?

  64. Wasn't this a STTNG episode by Anonymous Coward · · Score: 0

    I seem to remember Wesley Crusher doing something like this in the episode where he bagged Ashley Judd.

  65. 'published' in a 'journal' called PLOS one by Anonymous Coward · · Score: 0

    I love how MIT spins bits. PLOS One is not a journal in any common sense of the word. Consider it more of a community annotated 'blog' where you can send in manuscript, and if *one member* of the editorial board considers it technically (though not necessarily scientifically) sound, it gets posted.

    From the PLOS web site:
    Each submission will be assessed by a member of the PLoS ONE Editorial Board before publication. This pre-publication peer review will concentrate on technical rather than subjective concerns and may involve discussion with other members of the Editorial Board and/or the solicitation of formal reports from independent referees. If published, papers will be made available for community-based open peer review involving online annotation, discussion, and rating.

  66. Sounds more like a plan... by Anonymous Coward · · Score: 0

    to invent the perfect republican voter.

  67. IT is an April Fools Joke by Anonymous Coward · · Score: 0

    This is an early april fools joke.

    This "study" was conducted by members of the MIT Media Lab, yeah right
    the same people who are into wearable computers, also have a bio-med division?

    Yeah right, shine light upon a brain?? hmm a light bulb above the brain comic sketch?

    Get a clue,

  68. No.... by qazxswedc · · Score: 1

    I said BUD light.

  69. Terminal man by Frank+T.+Lofaro+Jr. · · Score: 1

    Learning more about the neural circuits involved in epilepsy could help scientists develop devices that can predict when a seizure is about to occur, allowing treatment (either shock or light) to be administered only when necessary, Boyden said.

    An automatic anti-seizure device was featured in the novel "Terminal Man". Hope this one would work better.

    --
    Just because it CAN be done, doesn't mean it should!
  70. Why would we do this? by Anonymous Coward · · Score: 0

    I wonder why we would bother to genetically alter people with epilepsy to exhibit a gene that we can use to cure them with light. Why wouldn't we rather focus on getting rid of the problem gene altogether?

  71. Works on drivers by Frank+T.+Lofaro+Jr. · · Score: 2, Funny

    Yellow light shuts down brain activity in the drivers here in Nevada quite well.

    Makes them forget that a yellow light means "go slow", not "go really really really fast".

    --
    Just because it CAN be done, doesn't mean it should!
  72. L.O.O.K.E.R. by HTH+NE1 · · Score: 2, Informative

    Nah. I think they're trying to make the Disco-Hypno gun from Looker
    Ah yes, the L.O.O.K.E.R. gun (Light Ocular Oriented Kinetic Energetic Responsers).
    --
    Oh, say does that Star-Spangled Banner entwine / The myrtle of Venus with Bacchus's vine?
  73. Looker by Richard+W.M.+Jones · · Score: 1
    Now we might be able to make one of those "freeze lightguns" from the 80's film The Looker?

    Rich.

  74. Presidential Memo To Slashdot: +1, Not under oath by Anonymous Coward · · Score: 0


    I, George W. Bush, President, United Gulags of America, being of somewhat sound mind and body, do hereby give notice to M.I.T that said technology is now the property of the Republican Party for the sole purpose of defending
    Freedom and Democracy(tm).

    Feloniously yours,
    W.

  75. I have seen the light... by Anonymous Coward · · Score: 0

    ...and now the rational part of my brain has stopped working :-(

  76. Easy. by RealProgrammer · · Score: 1

    We all have to eat Monsanto brand corn.

    This will have the added benefit of preventing athlete's foot.

    --
    sigs, as if you care.
  77. Eh, big deal. by mdm-adph · · Score: 1

    Commander Data already did this in "The Game."

    --
    It is by my will alone my thoughts acquire motion; it is by the juice of the coffee bean that the thoughts acquire speed
  78. Solution by PPH · · Score: 1

    Aluminum foil hats. Shiney side out.

    --
    Have gnu, will travel.
  79. That would explain... by Vitriol+Angst · · Score: 1

    ... the new Flashy Yellow graphics on Fox News.

    Though I'm sure an hour of the "Half our News Hour" will do the trick... they just want to make sure they have the latest brain-numbing technology.

    --
    >>"ad space available -- low rates!!!"
  80. And blue movies.... by EmbeddedJanitor · · Score: 1

    wake people up!

    --
    Engineering is the art of compromise.
  81. See also: melanopsin, receptor in human eye, sleep by ankhank · · Score: 2, Interesting

    This fits the discovery by Brainerd in 2001 that the human (and animal) eye has a receptor for blue light that controls the circadian clock.

    The cataract surgeons are debating whether it's safer to put in plastic replacement lenses that block blue (to maybe reduce the risk of eye damage from blue light), or if that's a bad idea. Turns out reducing blue during the daytime makes people sleepier.

    There's a lot to this; I wonder if the MIT folks know about the other work in the area of using blue light to stay awake, and low-blue or no-blue light for sleepiness.

    Can't quite tell from the bit online if this is the same chemistry or a different reaction.

    Quick link to a hugely informative site that collects this sort of info for science reference:

    http://64.233.167.104/search?q=cache:VaVv_OUCa4IJ: www.ihop-net.org/UniPub/iHOP/gismo/105192.html+%2B IOL+%2B%22blue+light%22+%2Balertness&hl=en&ct=clnk &cd=5&

  82. Somebody get that bulb out of by Master+of+Transhuman · · Score: 1

    the Oval Office...

    --
    Richard Steven Hack - This sig is TOO GODDAMN SHORT TO DO ANYTHING USEFUL WITH! MORONS!
  83. Sponge Bob, say it isn't so! by fahrbot-bot · · Score: 1
    invented a way to reversibly silence brain cells using pulses of yellow light

    This explains Sponge Bob (and the effects of TV in general).

    --
    It must have been something you assimilated. . . .
  84. In unrelated news by nedder · · Score: 1

    George Bush has had a desk lamp with this sort of bulb for about 6 years.

  85. Getting light in might not be particularly hard. by Medievalist · · Score: 1

    Six years ago, I saw a team of doctors at the A.I.DuPont Children's Hospital using an incredibly bright light to look inside a sick infant. When held behind the child's arm, you could literally see the every bone and muscle; the light shone right through bones at least as thick as the average human skull (which is quite thin, except in the case of politicians). The light did not burn or otherwise obviously damage the child, and she is fine today.

    Getting random neurons to take up new genes is probably doable, and supplying light to the entire brain non-invasively is probably doable, but the problems of targeting and control that you mention seem to be an order of magnitude more difficult... I don't think I'll be volunteering either.

  86. /b/tards? by Anonymous Coward · · Score: 0

    Alas, even Wikipedia cannot explain these jokes. Anyone care to clue a gaijin in?

    (What is rule 1, anyhow? Don't mess with football? Don't talk about 4chan? In Soviet Russia...)

    1. Re:/b/tards? by Anonymous Coward · · Score: 0

      I'll be broad, but his joke was generic.

      The forum is there mostly for pr0n, and has very active boards with different rules, sometimes to keep stuff on topic and people happy (you wouldn't want scat in the wrong place, would you?)

      I think Rule #17 or #34 is quoted often, and it's close to "NO 'raping' our childhood" [posting indecent pictures of cartoon characters or tv shows on the boards,] and another one says "Don't post AMERICAN cartoon derivatives." Some other one forbids child pr0n in any one of the boards.

      I haven't really read the rules in a long time, but people will jokingly quote them even in the freeforall, 99% rule-free /b/ ("random") board.

      PS: The namefags thing is about the fact that mostly anonymous posting is common. There isn't a real login system, so you can assume any name, but don't gain much "guarantee" of being its sole... (ab)user. To work around it, there's a password-to-randomlooking hash used in several other boards, where the name is accompanied by a hash sign and the random string. Since only you know your password, hashes are sort of signatures. Soo... namefags are people who like recognition so much that they just go thru the extra steps when everyone accepts and even welcomes anonymity.

    2. Re:/b/tards? by Anonymous Coward · · Score: 0

      Rule 1 = "Do not talk about /b/." Which is indeed a fight club reference, because that's also rule 2.

      http://www.encyclopediadramatica.com/index.php/Rul es_Of_The_Internet

      More than that it's practical advice, because the chans quite frequently raid forums / online games etc 'for the lulz' and do so under false colours to try and deflect legal / DDoS repercursions. Ebaumsworld are usually used, because they suck, they steal our memes and jews did 9/11.

  87. this explains something by Khashishi · · Score: 1

    all your brain are shutdown

  88. So what were rules 1-4? by Anonymous Coward · · Score: 0

    As best I can decipher, rule 1 must be about self-reference? No clue about 2-4, although one of them might be no posts about which rules others broke (which would make that even more ironic).

    And _ does not forgive sounds like a bad translation of a somewhat common Japanese phrase... which I can't remember right now (connection problems causing anime deficiency; I also think it wise not to visit 4chan from work to investigate). But I can't make any more sense out of it than that.

  89. So... by Nybble's+Byte · · Score: 0

    whose bright idea was this?

  90. Ways to stop the brain by bronsinbound · · Score: 1

    There are other ways to stop brain activity: a bullet comes right to mind (pun intended), and the Iraqi's look as if they've found others;^) Of course, only the Iraqi War is costing us more in tax dollars than this MIT study.

  91. what if.. by rubberbandball · · Score: 1

    the brain being treated is colorblind?

    --
    oh marmalade.
  92. Sign me up! by Seahawker101 · · Score: 1

    I've had seizures for 22 years now(since I was 6) and would welcome any type of treatment. I had a right-temporal lobectomy 11 years ago that didn't help, so this is a breakthrough that gives me some hope of finally being able to get off medication's and lead a semi-normal life.

    --
    Nothing inspires forgiveness quite like revenge.---Scott Adams