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Scientists Create Artificial Blood

simm1701 wrote us with a BBC article link on a sort of artificial blood substitute being developed by an English university. The substance is light, can survive at room temperature, and keeps longer than real blood, allowing it to be used as a stand-in in emergency situations. "The new blood is made up of plastic molecules that have an iron atom at their core, like haemoglobin, that can carry oxygen through the body. The scientists said the artificial blood could be cheap to produce and they were looking for extra funding to develop a final prototype that would be suitable for biological testing ... A sample of the artificial blood prototype will be on display at the Science Museum in London from 22 May as part of an exhibition about the history of plastics."

225 comments

  1. Thank god! by Anarchysoft · · Score: 2, Funny

    I was almost out of V8.

    1. Re:Thank god! by tibike77 · · Score: 4, Funny

      Vampires, rejoice ! Soon, the artificial blood project will be complete !
      New, in Italian, Mexican and Indian flavors.

      --
      By reading this signature you agree to not disagree with the post you just read.
    2. Re:Thank god! by Anarchysoft · · Score: 1

      Vampires, rejoice ! Soon, the artificial blood project will be complete ! New, in Italian, Mexican and Indian flavors. Wonderful! I hope they make hot and spicy too! :)
    3. Re:Thank god! by Tatisimo · · Score: 1

      What will happen to the immigrant workers at the blood factory :|? I'll stick to natural, for the sake of providing jobs.

      --
      Give Kashyyyk back to the Wookies
    4. Re:Thank god! by Bent+Mind · · Score: 4, Funny

      Nah, I'll stick with natural. This artificial stuff tastes too much like plastic.

      --
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    5. Re:Thank god! by cHALiTO · · Score: 1

      Quick!!!! Call Tang!!!

      --
      "Luck is my middle name," said Rincewind, indistinctly. "Mind you, my first name is Bad." -- Terry Pratchett
    6. Re:Thank god! by Anonymous Coward · · Score: 0

      I take it you've never had good Indian food!

    7. Re:Thank god! by Bloke+down+the+pub · · Score: 2, Funny

      Not Chinese? I suppose it'd taste nice, but after an hour you'd feel like another.

      --
      It's true I tell you, feller at work's next door neighbour read it in the paper.
    8. Re:Thank god! by Verteiron · · Score: 1

      You can't possibly be a vampire. Everyone knows of the vampire's deep-rooted fear of the letter "w".

      --
      End of lesson. You may press the button.
    9. Re:Thank god! by Anonymous Coward · · Score: 0

      With a hint of ketchup?

    10. Re:Thank god! by Anonymous Coward · · Score: 0

      Hey! all that effort just to make sinthetic blood sausages?

    11. Re:Thank god! by ATMD · · Score: 1

      Really? I thought it was the lower-case letter T?

      --
      Nobody else has this sig.
    12. Re:Thank god! by ATMD · · Score: 1

      In the heart of Transylvania
      In the vampire hall of fame, yeah
      There's not a vampire zanier than...

      --
      Nobody else has this sig.
    13. Re:Thank god! by Anonymous Coward · · Score: 0

      Soylent Green!

    14. Re:Thank god! by andy_t_roo · · Score: 1

      isn't the point about this blood that you can use it in situations where otherwise you would die so, even if it isn't as good as the real stuff, its better than dieing by a long way

    15. Re:Thank god! by Yvanhoe · · Score: 1

      I bet that without midchlorians it can't taste the same.

      --
      The Wise adapts himself to the world. The Fool adapts the world to himself. Therefore, all progress depends on the Fool.
  2. Re:Friday First Post!!1! by GundamFan · · Score: 0, Offtopic

    Have a good weekend you damn troll! :-)

    --
    I don't give a damn for a man that can only spell a word one way.
    Mark Twain
  3. Can I get it in green? by tod_baudais · · Score: 3, Insightful

    Can I get it in green?

    1. Re:Can I get it in green? by GundamFan · · Score: 4, Funny

      Perhaps a blue variety for the upper class English?

      --
      I don't give a damn for a man that can only spell a word one way.
      Mark Twain
    2. Re:Can I get it in green? by morari · · Score: 1

      I'd rather have purple... Like Goro!

      --
      "He who can destroy a thing, controls a thing." --Paul Atreides, Dune
    3. Re:Can I get it in green? by farrellj · · Score: 1

      Soylent Green is made from PEOPLE!!!!!!

      ttyl
                Farrell

      --
      CAN-CON 2019 - Ottawa's only book oriented Science Fiction Convention! October 18-20, Sheraton Hotel, Ottawa, Canada h
    4. Re:Can I get it in green? by LaurieDash · · Score: 1

      Red is just fine. Especially if you support Brown.

  4. lasting effects? by Turn-X+Alphonse · · Score: 3, Insightful

    But what about introducing plastic to the blood stream? Surely the body is going to flip out and attack it, which isn't exactly helpful in an emergency situation.

    --
    I like muppets.
    1. Re:lasting effects? by Applekid · · Score: 5, Interesting

      Not all plastics cause the body to flip out as you describe it.

      I'd be more concerned with where they go after the emergency is over. The spleen collects dead red blood cells... do the artifical ones "die"? What happens to the plastic then?

      IANAD, so, can any harm happen with an excess of red blood cells? Maybe this will lead to a future where some could supercharge their blood to maximize oxygen carrying ability.

      --
      More Twoson than Cupertino
    2. Re:lasting effects? by Anonymous Coward · · Score: 1, Insightful

      surely?

      Wow, it's a good thing the uniformed slashdot readers of the world who read a brief pop science summary thought of that one! I'm thinking, maybe...just maybe, the physicians and research scientists would have looked into that.

      Points to refute your comment:

      1) plastics can be extremely inert.
      2) The Immune response often takes several exposures to sensitize to foreign antigens.
      3) assuming mild allergic or immune attack in certain individuals, the therapeutic index on saving your life vs. potential issues down the road could easily be argued in favor of using the blood substitute.

      think man!

    3. Re:lasting effects? by _xeno_ · · Score: 5, Informative

      IANAD, so, can any harm happen with an excess of red blood cells? Maybe this will lead to a future where some could supercharge their blood to maximize oxygen carrying ability.

      It's called "blood doping" and people already do it.

      As for the rest of your question, IANAD either, and I'm curious about that too.

      --
      You are in a maze of twisty little relative jumps, all alike.
    4. Re:lasting effects? by amabbi · · Score: 4, Informative

      IANAD, so, can any harm happen with an excess of red blood cells? Maybe this will lead to a future where some could supercharge their blood to maximize oxygen carrying ability.


      Yes. The condition is called polycythemia, and most of the incidents involve the increased viscosity of blood leading to thrombus formation-- possibly causing heart attacks and strokes.

    5. Re:lasting effects? by SQLGuru · · Score: 2, Insightful

      Also, wouldn't it cause problems related to clotting and what not? Worst case, you get a plastic scab on a wound, but in reality, I would expect it to cause problems where you'd essentially become a hemophiliac because your blood could not coagulate. And doesn't the body already do "house cleaning" to eliminate blood periodically. What happens to all of that plastic that the body can't eliminate?

      Layne

    6. Re:lasting effects? by WormholeFiend · · Score: 1

      Surely the body is going to flip out and attack it, which isn't exactly helpful in an emergency situation.

      But that would be very useful for ninjas

    7. Re:lasting effects? by Znork · · Score: 1

      "can any harm happen with an excess of red blood cells?"

      NAD either, but if you consider common blood failure modes that would probably be in the realms of blood clots (plastic clots?), ie, too thick blood causing blockage, or blood not clotting (plastic blood doesnt result in breakage of blood cells at point of injury, and thus messes with triggers for clotting) and you get bleeding (which may or may not be a problem if you have an unlimited supply of plastic blood).

      I can certainly see the use, but the long term effects may be of some concern.

    8. Re:lasting effects? by Drooling+Iguana · · Score: 5, Funny

      I've heard that they did have a problem with the body's immune system flipping out and attacking the new artificial blood cells in early testing, but since they fitted each one of them with a miniature eyepatch and peg leg they've been able to defend themselves quite effectively.

      --
      ... I'm addicted to placebos
    9. Re:lasting effects? by Anonymous Coward · · Score: 1, Informative

      I thought clotting was caused by platelets, not red blood cells.

    10. Re:lasting effects? by Anonymous Coward · · Score: 0

      o/~ Because that's what ninjas do. o/~

    11. Re:lasting effects? by FictionalAccount · · Score: 5, Funny

      Turn-X furiously tapped away at his keyboard, sweat dripping from his brow. Time was of the essence, and he had to get his message out NOW.

      The story had just come up over the SlashWire, and unlike the usually dismissive drivel, this one caught his eye. Artificial blood. Something wasn't right here. They were going to investigate artificial blood? He thought back to his high school biology and that time he skinned his knee. Also that one program he saw on Nova. Blood...body...plastic...NO GOOD! My God, what if the body totally flipped out and went all attack mode on the blood! An emergency situation would be totally ruined!

      He had to act.

      Quickly he hit the reply button. The world needed to know before the scientists made an irreversible mistake. As fast as his fingers could go, he tapped out his response and hit sumbit. Now all he could do was wait. The story was fresh, so he might have caught it in time.

      Yes! There it was. The Slashmods had taken notice. A reply. A mod point. But not good enough...not yet. Minutes ticked by, the story was already the second down. Would he make it in time?

      Waiting...waiting...

      YES! +5 moderation! He sighed. His point was made, and now the world knew. The scientists would roll back their plans and head back to the drawing board.

      Turn-X would sleep well tonight.

      --
      Like what you read? Read more here.
    12. Re:lasting effects? by cephalien · · Score: 1

      Well, not really. The body's more active defenses are geared toward certain things; proteins, for example are -really- good at activating the immune system.
       
      Other things (carbohydrates, lipids) aren't so hot, but there are certain types of T-cells (Gamma-Delta T cells) that can initiate a T-cell receptor binding complex with those. My theory (DNRTFA) is that these plastic beads aren't going to do much. They're probably some sort of simple polymer that by itself isn't going to trigger any immune responses as long as it doesn't contain any particularly nasty compounds.

      --
      If firefighters fight fire, and crimefighters fight crime, what do freedom fighters fight? - George Carlin
    13. Re:lasting effects? by Sylver+Dragon · · Score: 1

      At a guess, the plastic molecule will probably end up being collected like dead blood cells and other foreign bodies in the blood stream eventually. And then eliminated in urine. Maybe it is a bit naive, but the people working on this stuff are much smarter than most of us on /. when it comes to biology, I'm sure they have thought of this.

      --
      Necessity is the mother of invention.
      Laziness is the father.
    14. Re:lasting effects? by nixkuroi · · Score: 3, Funny

      That's not a problem, that's a super power! If they could make these things from Kevlar, you put some in a guy, he gets shot and the wound scabs over with a bullet proof protective shell - finally realizing our dream of substantiating the "That which does not kill us, makes us stronger" cliche' we keep hearing about!

      Sign me up!

    15. Re:lasting effects? by RobNich · · Score: 1

      IANAD, but I do know that dead red blood cells are eliminated through the stool, not urine. They are broken down by the spleen and bone marrow, the globin converted to amino acids to be reabsorbed through the bloodstream. The rest of the cell remains are biliruben which the liver filters are excretes in bile into the small intestine.

      --
      Hello little man. I will destroy you!
    16. Re:lasting effects? by Moofie · · Score: 1

      Gosh, you ought to write to the doctors running the tests right away, because I'm sure they haven't thought of that.

      --
      Why yes, I AM a rocket scientist!
    17. Re:lasting effects? by Moofie · · Score: 3, Funny

      It is now my mission in life to be lampooned by you. I can't wait. : )

      --
      Why yes, I AM a rocket scientist!
    18. Re:lasting effects? by btgreat · · Score: 1

      If I remember correctly from my intro biology course, the body only detects foreign molecules by certain chemical groups on them, not just anything foreign. If the entire molecule had the same chemical nature as the cells, etc. of the person using the blood, or if it had no identifying groups whatsoever, the immune system wouldn't respond to it. As far as clotting is concerned, I don't really know how that works, but molecules as small as hemoglobin, even in large concentration, probably won't cause clotting. Especially if they are similar to things already present in the body.

    19. Re:lasting effects? by jakel2k · · Score: 1

      Sounds like you'll need to upgrade your spleen to an upgraded plastic one... the blood would be free but the spleen is extra.

      On a more serious note, red blood cells do break down naturally and absorbed into the body... the plastic would have problems doing this... I expect long term effects would surely be a problem...IANAD... maybe you'd have to go in for an annual blood change / oil change.

    20. Re:lasting effects? by jfengel · · Score: 1

      And if you've got xenopolycythemia, you've got less than a year to live. Unless you can find the cure on some artificial asteroid that you happen by chance to run into at precisely the time you're diagnosed.

    21. Re:lasting effects? by Bent+Mind · · Score: 1

      Also, wouldn't it cause problems related to clotting and what not? Worst case, you get a plastic scab on a wound, but in reality, I would expect it to cause problems where you'd essentially become a hemophiliac because your blood could not coagulate.

      Clots and scabs are made from platelets. I don't think that artificial red blood cells would affect the ability to clot.

      --
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    22. Re:lasting effects? by Aladrin · · Score: 1

      Personally, I'm kind of worried about it, myself... His accuracy is a little too uncanny. If he lampoons me, it'll mean I was devastatingly stupid about something.

      I don't like being stupid.

      --
      "If you make people think they're thinking, they'll love you; But if you really make them think, they'll hate you." - DM
    23. Re:lasting effects? by Ucklak · · Score: 1

      I was going to mention that the cure is in some book protected by a voice that can electrocute people on a whim but fail to stop people from opening a door.
      Also, if you are on this artificial asteroid, you can get married to the priestess and NOT change your clothes once you've resigned to the fact that you'll spend the rest of your life on said asteroid.

      --
      if you steal from one source, that is plagiarism, if you steal from many, well, that's just research.
    24. Re:lasting effects? by Rycross · · Score: 2

      Everyone is stupid about something at some point in their life. You just gotta sit back, relax, and laugh at yourself.

    25. Re:lasting effects? by Ucklak · · Score: 1

      I don't think that if you are one to receive this artifial blood that it would become an out-patient type of thing.
      They're not going to give you a shot of blood and say "See you back in 2 weeks!"

      You're going to be messed up and need blood yesterday to get this. You're going to be in a controlled environment and will probably have some IV type of thing in you to pull out the plastic cells once your body is able to produce it's own.

      --
      if you steal from one source, that is plagiarism, if you steal from many, well, that's just research.
    26. Re:lasting effects? by LWATCDR · · Score: 1

      Plastics tend can be very inert. As to getting rid of it. Well like most stuff that gets put into your blood I would guess that you will excrete it in your urine. I am sure that they have figured that all out.

      --
      See my blog http://ilovecookes.blogspot.com/ for light hearted technical information.
    27. Re:lasting effects? by Seedy2 · · Score: 1

      One wonders about hemochromatosis too.
      With all that "extra" iron floating around.

      --
      Nothing to say here... move along
    28. Re:lasting effects? by Anonymous Coward · · Score: 0

      liar

      And just because it's about you (yes it is liar) that's no reason to pretend that wasn't COMEDY GOLD!

      Get over yourself liar.

    29. Re:lasting effects? by camperdave · · Score: 1

      Xenopolycythemia, eh? What's the matter Bones, triox compound not good enough for you? You had to go and inject yourself with alien hemoglobin, didn't you? No, don't try blaming it on Spock. You're the doctor. You should know better.

      --
      When our name is on the back of your car, we're behind you all the way!
    30. Re:lasting effects? by bigred85 · · Score: 0

      Holy God that was beautiful.

      Was literally LOL in response to that.

      Kudos, good sir, kudos to you.

    31. Re:lasting effects? by SinGunner · · Score: 1

      Parent is considering the hypothetical situation where this artificial blood is introduced to a ninja body, which would undoubtedly flip out and attack the artificial blood.. and the doctor.. and everyone in a 10 mile radius.. Ninja bodies flip out all the time.

    32. Re:lasting effects? by smellsofbikes · · Score: 2, Informative

      Other people have answered, referencing blood doping, but nobody has pointed out quite how deadly this is. This article claims a dozen Dutch pro racers died of probable blood-doping-related heart issues in the late 1980's; through the pro racing grapevine people have claimed that the numbers were much higher than that.

      --
      Nostalgia's not what it used to be.
    33. Re:lasting effects? by Sylver+Dragon · · Score: 1

      Good thing I'm not a doctor either. ;-)

      --
      Necessity is the mother of invention.
      Laziness is the father.
    34. Re:lasting effects? by guruevi · · Score: 2, Informative

      Polycaprolactone? I don't know, just a guess, but I think if they ever go 'live' with this, they'll (have to) find a decent solution. PCL is bio-degradable plastic and I think it degrades in a human body (check Wikipedia or so to make sure). It's used a lot in the medical field.

      It's interesting to learn that they made these artificial oxygen carriers especially since blood is not simple to store and a lot of doctors are already starting to look at alternatives (saline solutions is a simple one) to add 'blood' volume when somebody loses some. This is because 'real' blood is difficult to store and handle and has the potential of disease. Another reason is that if you introduce somebody else's blood to your own bloodstream, your body will get symptoms that occur when transplanting other organs like rejection or even fatal shock (depending on the amount of blood administered).

      --
      Custom electronics and digital signage for your business: www.evcircuits.com
    35. Re:lasting effects? by Anonymous Coward · · Score: 0

      The real question is whether the anti-doping authorities have a reliable test for it, and whether any sports cheats are trying to use this, now that EPO users are getting disqualified.

    36. Re:lasting effects? by mrbluze · · Score: 2, Interesting

      I'd be more concerned with where they go after the emergency is over. The spleen collects dead red blood cells... do the artifical ones "die"? that happens to the plastic then?

      That's the point of the research, I guess. The obvious advantage is that since the stuff is totally synthetic, it is guaranteed to be sterile, hence the long shelf life. But I wonder along with you about them calling the stuff 'plastic'.

      Since the functions of a red blood cell (apart from carrying oxygen) include:

      1. Preventing the haemoglobin escaping and being degraded in the blood stream
      2. Reducing the osmotic (water pulling) effect of haemoglobin if it were free
      3. Keeping the haemoglobin in the blood stream and not letting it leak out everywhere
      4. Buffering acids and degrading some substances

      The questions that come to mind are:

      1. If we give this to patients, is it going to overwhelm their blood stream with solute?
      2. What happens to the iron - if it's released en masse will it result in iron toxicity?
      3. Presumably the plastic goes to the liver to get broken down. Is it going to cause problems there, such as cancers or compete with drugs?
      4. Sounds like a complex manufacturing process is going to need to be developed. Will they manage to get it right so that there are no contaminants?
      Unfortunately TFA has very little detail on it all.
      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    37. Re:lasting effects? by ch-chuck · · Score: 3, Funny

      the uniformed slashdot readers of the world

      There's a slashdot uniform? Where do I get one? What is it, some kind of green jumpsuit with special insignia on it?

      --
      try { do() || do_not(); } catch (JediException err) { yoda(err); }
    38. Re:lasting effects? by foniksonik · · Score: 1

      We already do this... it's called scar tissue. Great for short term survival... bad for future quality of life.

      --
      A fool throws a stone into a well and a thousand sages can not remove it.
    39. Re:lasting effects? by john83 · · Score: 1

      IANAD, so, can any harm happen with an excess of red blood cells? Maybe this will lead to a future where some could supercharge their blood to maximize oxygen carrying ability.

      It's called "blood doping" and people already do it.

      As for the rest of your question, IANAD either, and I'm curious about that too.

      I think it can cause blood clots, but I don't know how likely this is, how much over normal you have to be to have and/much trouble - IANAD either.
      --
      Strange women lying in ponds distributing swords is no basis for a system of government.
    40. Re:lasting effects? by marol · · Score: 1

      Dan Brown, is that you?

    41. Re:lasting effects? by Anonymous Coward · · Score: 0

      "Almost inconceivably, the gun into which she was now staring was clutched in the pale hand of an enormous albino with long white hair."

  5. What group is it? by Bastard+of+Subhumani · · Score: 4, Interesting

    I assume, though it's not mentioned, that it would be type neutral? That in itself would be a big advantage.

    --
    Only three things are certain; death, taxes, and apocryphal quotations - Ben Franklin.
    1. Re:What group is it? by illegalcortex · · Score: 2, Informative

      I would assume it wouldn't have antigens, as well (basically, it would be type O).

      But you may be interested in some new research that looks to be able to remove the antigens from regular blood, thus converting all blood types to type O.

    2. Re:What group is it? by GreyPoopon · · Score: 1

      But you may be interested in some new research [sciencedaily.com] that looks to be able to remove the antigens from regular blood, thus converting all blood types to type O.

      Darn it! Just when I was beginning to feel important! If they can convert any blood type to O, then what do they need me for?
      --

      GreyPoopon
      --
      Why is it I can write insightful comments but can't come up with a clever signature?

    3. Re:What group is it? by lawpoop · · Score: 1

      Blood types are description of antigens (or something like that) on the surface of blood cells. Types A and B are two different antigens; 0 means a lack of antigens. The +/- is the presence or absence of another antigen. So someone who is AB+ has A, B and + antigens, and their blood would be a problem for anybody but AB+ types. 0- has no antigens ( or at least, none of the antigens that cause problems), so they can donate to anyone. 0+ can donate to anyone who has +, B+ can donate to anyone with B+ -- people who are B+ or AB+. I may not be remembering this correctly so anyone more informed, please pipe up.

      Since the immune system has learned that your antigens are safe, it only reacts to 'foreign' antigens. If these plastic molecules or structure have no antigens, and they probably don't, then there is no problem with any blood type. But there may be other, non-antigen problems that crop up with this artificial blood. However, the benefits might outweigh the risks in a life-or-death situation.

      --
      Computers are useless. They can only give you answers.
      -- Pablo Picasso
    4. Re:What group is it? by illegalcortex · · Score: 1

      Well, they're still pretty far away from artificially created organs. So you've still got THAT.

    5. Re:What group is it? by illegalcortex · · Score: 1

      The +/- indicator is for the Rhesus D antigen, part of the Rhesus blood group.

      In reading a related wikipedia page, I see that the blood conversion technique does not remove the Rh D antigen. So the synthetic blood may have one up on it in this regard.

  6. that explains the vampires last night by swschrad · · Score: 4, Funny

    attacking my vinyl gutters and screaming, "plastic! PLASSSTIC! we must have plasssticcc!!!"

    threw 'em a floppy and shut the window.

    --
    if this is supposed to be a new economy, how come they still want my old fashioned money?
    1. Re:that explains the vampires last night by Tablizer · · Score: 3, Funny

      attacking my vinyl gutters and screaming, "plastic! PLASSSTIC! we must have plasssticcc!!!" threw 'em a floppy and shut the window.

      Use #462 for AOL disks: Vampire Decoy

    2. Re:that explains the vampires last night by foniksonik · · Score: 1

      Those weren't vampires, they were illegal immigrants and they just wanted a fake id.... well they could have been identity thieves on hard times... reduced to begging for your credit cards instead of stealing them like any self-respecting ID thief.

      --
      A fool throws a stone into a well and a thousand sages can not remove it.
    3. Re:that explains the vampires last night by Jotii · · Score: 1

      attacking my vinyl gutters and screaming, "plastic! PLASSSTIC! we must have plasssticcc!!!"
      So that's where the ICQ numbers went.
      --
      [sig]
  7. Won't be a big hit. by t_ban · · Score: 2, Funny
    vampires will continue to prefer organic.

    --
    First they ignore you. Then they laugh at you. Then they fight you. Then you win. -Gandhi
    1. Re:Won't be a big hit. by dr_dank · · Score: 2, Funny

      Two words: vampire methadone.

      --
      Where does the school board find them and why do they keep sending them to ME?
    2. Re:Won't be a big hit. by flyingfsck · · Score: 1

      Uhh, plastic is organic, so is wax, petrol, diesel, coal, oil, tar and most pesticides... Organic stuff is not necessarily edible or healthy.

      --
      Excuse me, but please get off my Pennisetum Clandestinum, eh!
    3. Re:Won't be a big hit. by poopdeville · · Score: 1

      You mean plastics are made by living organisms? Sorry to break it to you, but outside of a few exceptions, most plastics are synthetic. Same with gasoline, diesel, and insecticides.

      Oh, you mean plastics fall in the realm of organic chemistry. Only an autistic person would confuse the two concepts (relating to organisms versus the chemistry of hydrocarbons).

      --
      After all, I am strangely colored.
    4. Re:Won't be a big hit. by C0rinthian · · Score: 1

      F--ing Hippy Vampires. *grumblegrumble*

    5. Re:Won't be a big hit. by Anonymous Coward · · Score: 0

      .. town is full of 'em!!

  8. Artificail Blood is old news by jr01945 · · Score: 5, Informative

    There are already a few companies making artificail blood in the US. One is Biopure. All of them are waiting either for the completion of clinical trials or FDA approval. The Biopure product has already been approved in other countries.

    1. Re:Artificail Blood is old news by Mab_Mass · · Score: 1

      Yes, but did you notice (from the summary) that this is an artificial blood substitute? You know, for those that don't like the regular artificial blood.

    2. Re:Artificail Blood is old news by Anonymous Coward · · Score: 0

      Biopure are simply using bovine blood. This is notable because it is completely synthetic. Are either of them *right*, who knows? Plastic blood or cows blood - neither sounds all that good to me.

    3. Re:Artificail Blood is old news by Yvan256 · · Score: 1

      So in some way it's like someone who's trying to make a substitute for Splenda?

    4. Re:Artificail Blood is old news by Spazntwich · · Score: 1

      I'm confident either will start sounding a lot better than various type O trauma victims are living through what would have otherwise been fatal incidences.

    5. Re:Artificail Blood is old news by Anonymous Coward · · Score: 0

      The obvious advantages are that it doesn't need refrigeration, can be transported in a thick paste to be rehydrated later, and doesn't use any biological precursor that might carry unknown pathogens.

      Besides, here's the press release : http://www.shef.ac.uk/mediacentre/2007

    6. Re:Artificail Blood is old news by Anonymous Coward · · Score: 0

      The only way that would make sense is if you're a vampire.

  9. Respiration by polyomninym · · Score: 1

    I can't help but to imagine robots that breathe for some reason.

  10. Hmm by El+Lobo · · Score: 2, Informative

    Correct me if I am wrong, but a blood replacement is being used since the 80s. If I recall it correctly it was also some kind of artificial plasma. Jehova's witnesses (a group known by their non acceptance of blood transfusions) have beeing accepting this blood replacement for years now.

    --
    It's time to realise that Abble's products are the biggest abomination these days. Just say NO to the dumb iAbble way!!
    1. Re:Hmm by GundamFan · · Score: 1

      I'm guessing the innovation here isn't that this is a plasma replacement so much as it is a way to replace blood cells, which I assume would be combined with an artificial plasma product to produce artificial "whole blood" that is typeless, free of biological contaminants and most of all able to be manufactured as needed.

      --
      I don't give a damn for a man that can only spell a word one way.
      Mark Twain
    2. Re:Hmm by Anonymous Coward · · Score: 0

      Your signature makes me want to buy a gun.

    3. Re:Hmm by Mockylock · · Score: 1

      You can actually use cocount milk for plasma. Using almost any blood/plasma can be used ONCE. But after the second time around, you're dead.

      --
      "Please, shut up. Just when I think you can't say anything more stupid, you speak again." -Archie Bunker.
    4. Re:Hmm by Anonymous Coward · · Score: 0

      Jehova's witnesses (a group known by their non acceptance of blood transfusions)

      Official Jehovah's Witness blood doctrine has many loopholes and contradictions. They explicitly allow partial transfusions. Regarding full blood transfusion, they used to threaten their members with excommunication but now allow it (based on "conscience"). This is likely because of numerous legal threats arising from the deaths of JW children.
    5. Re:Hmm by boring,+tired · · Score: 1

      This is the stuff: Fluosol

    6. Re:Hmm by Mattintosh · · Score: 1

      There have been many "blood expanders" on the market for many years now, and that has been a great help to Jehovah's Witnesses in emergency medical situations. However, those mostly are used to dilute the blood so that during surgery fewer red cells are lost.

      However this appears to be an artificial source of red cells, and would be an even greater boon to medical science (and in the short term, a huge help for JW's undergoing medical treatment) since it eliminates many of the problems (physical problems for everyone, and moral problems if you're a JW) with blood transfusions. There should be no issues with tissue rejection (I'm sure these will be designed to minimize rejection, and may even contain light doses of anti-rejection drugs in the mix). There should be no issues with matching types (These will undoubtedly be either type-neutral or be manufactured in major quantities in all types, thus no shortage and no need to substitute another type).

      My take on this advancement is that this is a major Good Thing, regardless of your moral viewpoint.

      IAAJW. YMMV. HTH. HAND.

    7. Re:Hmm by C0rinthian · · Score: 1

      I am so glad I never needed a transfusion as a kid. (JW parents)

    8. Re:Hmm by Anonymous Coward · · Score: 0

      Actually, the issue hasn't changed at all. What has changed are the methods of treating blood loss and the choices that a person now has available to them. The matter of conscious is only applicable for the methods used to prolong your life. Whether you want to accept substances that contain portions derived from blood or if you would allow your own blood to exit your body, circulate through a machine and re-enter the body again, effectively extending your own body's circulatory system through artificial means. These matters are based on one's conscious, not the decision of whether or not to partake of blood, which is and always will be against God's commandments (Acts 15:29). And yes, one who willfully accepts blood in order to prolong his life will receive discipline which might include being expelled from the congregation.

  11. true by wizardforce · · Score: 1

    But what about introducing plastic to the blood stream? Surely the body is going to flip out and attack it, which isn't exactly helpful in an emergency situation.
    the body does attack certain polymers proteins being an example of this as in incompatible blood types and a possible solution could be to coat the compound in a coating that the body doesn't attack- like its own proteins or something along those lines like an artificial blood cell.
    --
    Sigs are too short to say anything truly profound so read the above post instead.
  12. Silicon by blhack · · Score: 0

    i would like to know the long term side effects of this. Look at when breast implants were first appearing. They used silicon, and thought it was completely safe, but after some of the implants starting rupturing, they found out that some of the side effects can be horrendous. I would hate to see the same thing with this. I would especially hate to see that happen if using this substance wasn't ABSOLUTELY necessary. Imagine if use of this substance eventually becomes wide spread, people stop donating blood, and a year down the road we find out the stuff causes cancer or something.

    IMHO, the research dollars would be better spent on developing a process to grow "natural" blood. Honestly i think that any research into the artificial growth of body parts, (like what has been done with mice and ears) is a step in the right direction. Use blood as a starting point and work up from there.

    --
    NewslilySocial News. No lolcats allowed.
    1. Re:Silicon by jayayeem · · Score: 4, Insightful

      The side effects of losing 3 liters of blood before I can get you to the hospital are already well known and likely to be worse than the side effects of artificial blood. The big news here is that it could be stored longer with less refrigeration, so I can carry it on my bus.

      --
      I metamoderate, therefore I am
    2. Re:Silicon by Anonymous Coward · · Score: 0

      First of all, it's silicone, unless you're talking about a creative place to put an implanted computer. Second, the whole thing was a hoax thought up by lawyers.

    3. Re:Silicon by Tanuki64 · · Score: 1

      I don't think you have to worry about this. Of course this blood surrogate will only be used when it is absolutely necessary, e.g.. to replace a large blood loss when no fitting natural supply is available. What else can it be good for? It might provide the tissue with oxygen, but one thing it surely cannot do: Clot.

    4. Re:Silicon by Red+Flayer · · Score: 1

      IMHO, the research dollars would be better spent on developing a process to grow "natural" blood.
      This could have the added benefit of using the research dollars simultaneously to fund orphanages.

      Seriously, though. Blood is a pretty complex fluid, we've got RBCs, WBCs, platelets, trace hormones.

      How would one grow RBCs? They have no nucleus, and thus can't be cultured, and you need so many that it would be a waste of stem cells to culture from there.

      WBCs? Maybe from stem cells, if we can figure out how to differentiate them properly.

      Platelets? Probably the easiest, since you could use your RBC failures as starting points.

      However, we all know how to make a hormone, which is by not paying her.
      --
      "Trolls they were, but filled with the evil will of their master: a fell race..." -- J.R.R. Tolkien on Olog-hai
    5. Re:Silicon by nasor · · Score: 1

      "Look at when breast implants were first appearing. They used silicon, and thought it was completely safe, but after some of the implants starting rupturing, they found out that some of the side effects can be horrendous."

      No, a few opportunist lawyers managed to whip people into a lawsuit frenzy by claiming that any and all medical ailments suffered by a recipient of silicon breast implants must have been caused by the implants.

      The successful lawsuits against Dow and the other companies involved in silicon breast implants are a perfect example of "style over facts". There was zero evidence that the implants were causing problems, but when the juries saw a woman on the witness stand crying about how a big heartless corporation had ruined her health, the juries switched off their brains and ruled against the "big, evil company."

    6. Re:Silicon by osu-neko · · Score: 1

      IMHO, the research dollars would be better spent on developing a process to grow "natural" blood. Honestly i think that any research into the artificial growth of body parts, (like what has been done with mice and ears) is a step in the right direction. Use blood as a starting point and work up from there.

      Well, these silly scientists tend to prefer evidence over speculation, so they'd say research dollars should be spent on both, and conclusions as to which approach is better should be drawn from the resulting evidence, rather than having someone arbitrarily decide ahead of time which approach is better, based on no real evidence.

      --
      "Convictions are more dangerous enemies of truth than lies."
    7. Re:Silicon by Goeland86 · · Score: 1

      Actually, there was a problem with the early implants, but it was a manufacturing defect that the company tried to cover up.
      There's a reason you can still get silicon implants in Europe: longer research and more quality control of said implants.
      The FDA is currently considering re-allowing silicon implants, given the advances in making safer containers.

      --
      ---- I am certain of only one thing : I know nothing else.
    8. Re:Silicon by dubbreak · · Score: 5, Funny

      They used silicon..

      but they found that flat square boobs weren't fashionable so they moved to using silicone.

      --
      "If you are going through hell, keep going." - Winston Churchill
    9. Re:Silicon by Incadenza · · Score: 2, Insightful

      i would like to know the long term side effects of this.

      Yes, why switch to something new when we have a well-tested system, blood donations, that is totally free of long term side effects, and has always been 100% safe.

    10. Re:Silicon by fireboy1919 · · Score: 1


      IMHO, the research dollars would be better spent on developing a process to grow "natural" blood.


      IMHO, the research dollars would be better spend on developing a means where I can fly using the power of my mind. Because that's cool.

      I know that it'll cost a lot more than the other thing, and maybe isn't possible, but I'd much rather have that. Those boring pragmatists striving after achievable goals need to start thinking about what I want.

      Honestly i think that any research into the artificial growth of body parts, (like what has been done with mice and ears) is a step in the right direction.

      Actually, what they need to do is watch X-Men. That will give them an idea of what I'm going for. We can start with being able to create flames from my mind and work up from there. While I'm not a biologist, and don't know anything about how these powers are going to be developed, it's probably a step in the right direction.

      What are we waiting for? We need to get to work on this. Those mental flying powers aren't going to design themselves.

      --
      Mod me down and I will become more powerful than you can possibly imagine!
    11. Re:Silicon by bobcat7677 · · Score: 1

      Carry it on your bus eh? Just in case the bus crashes and your leg is violently severed from your body? Now THAT is being prepared!

      Anyway, I don't get why everyone gets so up in arms about testing stuff. If you want to find out if it works, the only good way is to have some brave volunteers try it out and see what happens. It's dumb to jump into something blindly. It's dumb to fully trust something before it's effects have been scientifically observed over time in the indended working evironment (in this case the human body). And it's also dumb to dismiss something because testing it might lead to the testee's death. Progress very rarely comes without risks.

      That is all.

    12. Re:Silicon by Oniko · · Score: 3, Informative

      I'm guessing the GP meant "bus" as emergency-type-folk slang for ambulance. And, yeah, there's risks in everything, but it's generally best to minimize those risks. I'd sooner err on the side of pre-human testing than not. And getting "up in arms", or putting the burden of proof of risk vs. benefit on the tester, is a prudent way to do that.

    13. Re:Silicon by kd3bj · · Score: 1

      People shouldn't donate blood now. Do you think the artificial blood inventors and manufacturers will donate their technology? Do doctors donate their time? Do nurses? Do the people who process blood from blood donations donate their time? Health care is a giant commercial industry. Asking people to donate blood is like asking the Saudis to donate oil.

    14. Re:Silicon by ozphx · · Score: 1

      Tell that to my mate who caught Hep-C from blood that got thru screening in au...

      --
      3laws: No freebies, no backsies, GTFO.
  13. Old News.. by Anonymous Coward · · Score: 2, Interesting

    Posted Anon because I don't care about Karma. These guys may have invented a new type of fake blood but its not a new thing.

    http://en.wikipedia.org/wiki/PolyHeme

    http://en.wikipedia.org/wiki/Blood_substitutes

    There was a big stink a while back about FDA trials without consent. The problem is if your in shock and being serviced by first responders you don't really have time to fill out a consent form and the EMT's can't carry real blood with them so synthetic blood is the only option.

    1. Re:Old News.. by Timesprout · · Score: 1

      you don't really have time to fill out a consent form and the EMT's can't carry real blood with them so synthetic blood is the only option.
      Not the only option, in case of emergency I would always be open to having a few bloody marys administered.
      --
      Do not try to read the dupe, thats impossible. Instead, only try to realize the truth
      What truth?
      There is no dupe
  14. Not Exactly New by good+soldier+svejk · · Score: 1, Informative

    Blood substitutes have been around for a while. I remember seeing a demonstration of perfluorocarbon based artificial blood in the early 1980s. You could also breath the stuff. Or at least, the mouse they dropped in it could. This is a differrent approach, artificial hemoglobin, but I think there have been previous versions of that as well.

    --
    It is cowardly, and a betrayal of whatever it means to be a Jew, to act as a white man

    -James Baldwin
    1. Re:Not Exactly New by Anonymous Coward · · Score: 0

      There was even a UFO episode where the aliens used a liquid breathing system. Striker or his second (I don't remember the guys name offhand) got captured by the aliens and at some point was using one of their space suits and it had liquid instead of gas to breath with.

    2. Re:Not Exactly New by Script+Cat · · Score: 1

      I remember reading about a product called Oxygent that was undergoing clinical trials a couble years back. But I could never find much about the results. There is a wikipedia page but it's very sparce.
      http://en.wikipedia.org/wiki/Oxygent

    3. Re:Not Exactly New by What+is+a+number · · Score: 1

      That's Incredible!

      ---
      I type this every time.

  15. uhh, but now you are introducing typing again by swschrad · · Score: 1

    every body protein has irregularities, and now you are going to invite the body to start attacking the fake blood. get out occam's razor and start slicing your theory...

    --
    if this is supposed to be a new economy, how come they still want my old fashioned money?
    1. Re:uhh, but now you are introducing typing again by wizardforce · · Score: 1

      every body protein has irregularities, and now you are going to invite the body to start attacking the fake blood.
      even type-o blood has proteins- they just are not attacked as readily as the antigen marker compounds are. what I am suggesting is to use some compound- any compound that has little if any known immunological reaction.
      --
      Sigs are too short to say anything truly profound so read the above post instead.
  16. Blood Replacement for Emergencies? by ErikInterlude · · Score: 1

    I'd have to do some digging through the Slashdot archives, but I remember something similar mentioned a year or two ago. The story at the time was that artificial blood was being created with the idea of replacing blood in a patient undergoing emergency surgery. The real blood would be stored while the fake blood would provide oxygen and nutrients to keep the patient alive while being operated upon. Once everything is finished, the real blood is re-introduced to the body. I don't know how injuries causing grievous blood loss would be handled, though.

    --

    --Erik
  17. bad analogy by Anonymous Coward · · Score: 1, Insightful

    silicon implants are messy when they rupture, but there is still no evidence at all they they cause systemic illnesses. Successful lawsuits do not determine science. Your point is still valid, but that is why studies are needed.

  18. Pamala Anderson by Archangel+Michael · · Score: 1

    And now, Pam can complete her plastic makeover.

    --
    Agent K: A *person* is smart. People are dumb, stupid, panicky animals, and you know it.
  19. Finally the link between Blood for Oil by Ober · · Score: 0

    Given oil is used to make plastic..

  20. No more need for Bart... by PHAEDRU5 · · Score: 1
    --
    668: Neighbour of the Beast
  21. Blood, but not plasma by antifoidulus · · Score: 1

    Good, otherwise I would lose my main source of livelihood :P

  22. Can I get it in cows? by Mahjub+Sa'aden · · Score: 5, Funny

    Forget different colours. What we should do is genetically modify cows to produce blood instead of milk. How awesome would that be?

    Although it would give a whole new meaning to "clotted cream".

    --
    What is is all that is. Isn't that obvious?
    1. Re:Can I get it in cows? by C0rinthian · · Score: 5, Funny

      I think Cows produce that already, but I'm no biologist...

  23. The Singularity is Near.... by PHAEDRU5 · · Score: 5, Interesting

    I attended a lecture by Ray Kurzweil, where he talked about medical breakthroughs that are on the point of revolutionizing human life.

    Among other things he talked about blood substitutes, describing how the day is near when you'll be able to take a single deep breath and sit on the bottom of your pool for 15+ minutes, so efficient will be your (artificially enhanced) uptake of oxygen.

    He gave a great speech. I recommend his book, "The Singularity is Near."

    --
    668: Neighbour of the Beast
    1. Re:The Singularity is Near.... by kurzweilfreak · · Score: 1

      I recommend "The Age of Spiritual Machines" before you move on to "Singularity Is Near" as it provides quite a bit of information that helps you understand the latter.

      --

      kurzweil_freak

      5th Kyu Genbukan Ninpo/KJJR student

      Be the darkness that allows the light to shine.

    2. Re:The Singularity is Near.... by fbjon · · Score: 2, Informative

      Unfortunately, it's not low blood oxygen level that triggers breath hunger, it's high CO2 levels, so I doubt a blood implant would give 15-minute pool sitting benefits.

      --
      True confidence comes not from realising you are as good as your peers, but that your peers are as bad as you are.
    3. Re:The Singularity is Near.... by sxtxixtxcxh · · Score: 0

      i'm sure in 15 minutes, one could exhale all that excess CO2... i'm no sitting-on-the-bottom-of-the-pool-for-15-minutes-u sing-highly-efficient-blood-substitute expert though.

      --
      for a minute there, i lost myself...
  24. Pro Peloton by Anonymous Coward · · Score: 0

    The real question is, how long will it be before you see it widely used in the pro peloton, and will they be able to detect it's use. :)

  25. Platic Blood by jusDfaqs · · Score: 1

    The new blood is made up of plastic molecules that have an iron atom at their core, like haemoglobin, that can carry oxygen through the body.

    Does this mean that with this "new" type of synthetic blood that they would be able to do a more targeted delivery of specific type of medication, ie.. Cancer treatments, HIV/AIDS Medications and what not?

    *AND*,
    hemoglobin is spelled wrong in the article so says the /. spelling dictionary :-)
    --
    There are only two steps in the gathering of ultimate knowledge. Open your eyes and, RTFM!
    1. Re:Platic Blood by Anonymous Coward · · Score: 0

      "hemoglobin is spelled wrong in the article so says the /. spelling dictionary :-)"

      Well the /. dictionary needs to STFU because it's wrong.

    2. Re:Platic Blood by dfgchgfxrjtdhgh.jjhv · · Score: 1

      haemoglobin is the english spelling, hemoglobin is the american spelling. the article is from the bbc.

  26. better link by wizardforce · · Score: 1

    Here's a link about the blood substitute in more detail
    http://technology.guardian.co.uk/weekly/story/0,,2 075544,00.html

    --
    Sigs are too short to say anything truly profound so read the above post instead.
  27. Perfect timing by Nybble's+Byte · · Score: 0

    It's what all the wannabe Draculas will be drinking at Halloween.

  28. on another note by Chris+whatever · · Score: 1

    they strongly discourage the use of this blood below 0 degree celsius, it is said it stiffens the body.

    1. Re:on another note by Eternauta3k · · Score: 1

      If your blood is at 0C you're either dead or a fish.

      --
      Yeah. Would you choose a neurosurgeon who pokes around people's brains in his spare time? I wouldn't.
    2. Re:on another note by Chris+whatever · · Score: 1

      it was meant as a joke, plastic stiffens the colder it gets, meaning that someone who just got a transfusion with this type of blood would have problem if it's cold outside.

  29. I heard... by monoqlith · · Score: 1

    they've already administered a trial batch to Dick Cheney.

  30. cakewalk for boris by Anonymous Coward · · Score: 0

    OMFG! I thought thin blood would keep me from being tortured for long for saving people's lives...

  31. Margarine for vampires by ProteusQ · · Score: 1

    "Drink this? I'd rather be dead!"
    -- Bela Lugosi

  32. Strange.. by Mockylock · · Score: 1

    Couldn't they find something else that was a bit degradable? This would have to have some affect on capillaries throughout the body, not to mention the brain. How would one actually rid their body of these cells in the long run?

    Better yet, how is someone's wounds going to clot up? I'm guessing you'll look like you have silly putty oozing from your bandage.

    --
    "Please, shut up. Just when I think you can't say anything more stupid, you speak again." -Archie Bunker.
    1. Re:Strange.. by CpnTripps · · Score: 1

      They just have you swallow a few magnets. The iron at the core sticks to the magnets and you pass it all back out as a big clump :)

      I don't think I'd want to be second in line for the treatment when they reprocessed the stuff, though.

      A curious side effect of the treatment is, after walking under high voltage power lines, you can float in a swimming pool and your head always points north.

    2. Re:Strange.. by Mockylock · · Score: 1

      Yeah, I agree... they also said they had a way to use cattle or pig plasma now, didn't they?

      --
      "Please, shut up. Just when I think you can't say anything more stupid, you speak again." -Archie Bunker.
    3. Re:Strange.. by Blublu · · Score: 1

      I would advice against swallowing more than one magnet. Think about it!

      --
      meh
    4. Re:Strange.. by iamlucky13 · · Score: 1

      Why does everyone assume that anything with the term plastic in it is non-degradable? Besides, it's not like doctors are allowed to just stick things in a person's body on a whim.

      Take a step back from the knee-jerk, luddite reaction to technology and think for a second about what the article is talking about here: an emergency supply of blood that is easier to store, transport, and perhaps even acquire (cheaper than drawing blood?). Complications from a foreign substance in your body are pretty minor compared to dying from blood loss, and the kinds of places where transfusions are needed are not always well-suited to the storage of spare blood (like in a medic's fieldpack in 100+ degree heat in Falluja).

      </rant>

      It's likely they've thought of this and chosen their materials accordingly. Even if the body isn't able to dispose of the artificial hemoglobules itself, it's likely that they could be transfused out (or possibly simply bled out, since you noted that these probably don't denature and clot like platelets). Furthermore, adding stuff to the blood stream does not necessarily stop the body's natural blood production, and it's not like they're claiming their artificial blood is ready for use yet, anyway.

  33. Or worse, get a doctor's excuse for it... by Anonymous Coward · · Score: 0

    Floyd Landis was just one of 18 or so cyclists in last year's Tour de France who was caught on that particular type of drug test.

    The other 17 had doctor's notes.

    No shit.

    http://trustbut.blogspot.com/

  34. Easy Cleanup by Anonymous Coward · · Score: 0

    I hoping to make the switch to synthetic for the "rituals" as cleanup will be easier. Less litigation too!

  35. dirty laundry by White+Yeti · · Score: 1

    Does it stain?

  36. No "cells" are in this synthetic blood substitute by Anonymous Coward · · Score: 1, Informative

    There aren't any "cells" in this artificial blood. It's only a mixture of compounds that can transport oxygen via individual molecularized constructs.

  37. I for one welcome our new blood-enabled cyborgs by WillAffleckUW · · Score: 1

    And am proud that we can now give them artificial blood as they build our Future of Tomorrow today!

    --
    -- Tigger warning: This post may contain tiggers! --
  38. Aspertame by king-manic · · Score: 3, Funny

    It's Aspertame for vampires.

    --
    "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy."
  39. Fake Blood by emudoug42 · · Score: 2, Funny

    You rock me like the real thing... and if you were the real thing, you'd rock me even more

  40. This isn't new... by Anonymous Coward · · Score: 0

    This unfortunately isn't new... Dr. Chang at McGill has been working on this for quite a while... see artificial cells: http://www.medicine.mcgill.ca/artcell/artcell.htm
    surprise surprise how old news is suddenly new news :P

  41. Why is this news? by thePowerOfGrayskull · · Score: 1, Insightful
    Soo... why is this news when there hasn't even been animal testing yet?

    I wonder why it's colored red, too. Is it just to make people feel better, or did all the iron atoms start to rust...

  42. Old Man's War? by John+Whorfin · · Score: 1

    SmartBlood (tm)

  43. Can You Imagine... by LEX+LETHAL · · Score: 1

    In A Few Years...

    Plastic blood enhanced with teflon nanoplating.

    WHAT'S IN YOUR BLOODSTREAM?

  44. Artificial blood for my cat by AlpineR · · Score: 4, Interesting

    My cat got very sick a few years ago after being bitten by a raccoon. When the local vet couldn't diagnose the problem we took him to the College of Veterinary Medicine at Michigan State University. The cat couldn't even stand up and was fading fast so they wanted to give him a transfusion. But when they tried to match his blood type the samples reacted against every donor they checked. So they offered to try an experimental artificial blood.

    The artificial blood kept him alive long enough to identify a parasite infection, start him on treatment for the parasites, and let him recover until a natural blood donor could be found and infused. He was hospitalized for over a week but finally recovered and is perfectly healthy now. The interesting side effect is that he bulked up massively since the illness. He's over twenty pounds and extremely muscular. I don't know which artificial blood they used and what other side effects it had, but it seems like it might have more applications beyond just blood replacement for emergencies.

    AlpineR

    1. Re:Artificial blood for my cat by Anonymous Coward · · Score: 0

      It was some super cat-soldier serum they had left over from WW2.

    2. Re:Artificial blood for my cat by Vegeta99 · · Score: 1

      Here's my off-the-cuff theory:

      If it was the same thing here, plastic molecules with an iron complex in them, perhaps the plastic couldn't be broken down.

      It also wouldn't be detected by the body's endocrine system. Therefore, once your pet got better, he started generating the required amount of RBC's for him to function regularly - except that his blood already has the permanent synthetic RBCs in it!

      I really shouldn't be a psychology major.

    3. Re:Artificial blood for my cat by wesborgmandvm · · Score: 2, Informative
      The "experimental artificial blood" was a product called Oxyglobin. While it is approved for dogs it may still be considered off label when used in cats. However the reason your cat bulked up was not from the Oxyglobin, it was because the parasites were gone. It is likely the parasites were causing a sub-clinical illness (and wt loss) for months or years before getting sick.


      http://www.biopure.com/shared/home.cfm?CDID=2&CPgI D=54

    4. Re:Artificial blood for my cat by LordP · · Score: 5, Funny

      Your cat has been in training and is out looking for that damn raccoon to exact vengeance.

      --
      Nothing is so smiple that it can't be screwed up.
    5. Re:Artificial blood for my cat by syousef · · Score: 1

      Radioactive spiders^H^H^H^H^H^H^Hracoons???

      --
      These posts express my own personal views, not those of my employer
    6. Re:Artificial blood for my cat by john83 · · Score: 1

      Your cat has been in training and is out looking for that damn raccoon to exact vengeance. There may even have been a montage at some point.
      --
      Strange women lying in ponds distributing swords is no basis for a system of government.
  45. Hemoglobin, not plasma by anno1602 · · Score: 1

    AFAIK, plasma transports only limited amounts of oxygen and thus cannot completely replace blood. It can make up for some lost mass, but if all you have in your veins is plamsa, you're dead.

  46. would you like a by printanddestroy · · Score: 1

    Blood Lite with that sucking chest wound?

  47. WTF is a "plastic molecule"? by anno1602 · · Score: 1

    PE? PP? PVC? Or are they using it to say "designer organic polymer"?

  48. Lots of benifets beyond medical necessity by jfmiller · · Score: 4, Interesting

    IANAD, but I have worked as a hospital chaplain.

    This is a big deal for a lot of reasons. I'd like to point out a few of the less obvious

    Jehova's Witnesses have already been mentioned, but add to this list dome forms of Judiasm, branches of Meninite Christianity, and others as divers as the Hmong refuse blood transfusions. Artificial plasma (sometimes called artificial blood) is acceptable as are the use of cell savers. Unfortunately neither of these are effective against the uncontrolled loss of blood, or against blood based diseases that kill of red blood cells. The ability to artificially add O2 capacity and not just volume to the blood will a very welcome thing for these groups. From first hand experience being with families, I can tell you that no matter what the ultimate decision, being caught between needing blood and keeping faith is a heart breaking and guilt ridden experence for doctors, patients and families.

    The other issue I want to bring up is the trust of the blood supply. There is an unfortunate and sad history of treating minorities in the US with inferior medicine, which has included infected blood. The rumors that such practices are ongoing persist particularly in the homeless populations. My perception from talking with some of the people who believe these rumors is that artificial blood would be perceived as safer. Perception is often stronger then reality when it comes to patient compliance, and even if this remains a sub-optimal solution when compared to whole blood (my guess is this will remain the case though IANAD) it is better then refusing treatment.

    I hope that this is proven to be save and effective.

    --
    Strive to make your client happy, not necessarly give them what they ask for
    1. Re:Lots of benifets beyond medical necessity by Hatta · · Score: 2, Interesting

      I can tell you that no matter what the ultimate decision, being caught between needing blood and keeping faith is a heart breaking and guilt ridden experence for doctors, patients and families.

      Yeah but for secular darwinists it's a laugh and a half.

      --
      Give me Classic Slashdot or give me death!
    2. Re:Lots of benifets beyond medical necessity by IHC+Navistar · · Score: 1

      The medicine that minorities get comes from the SAME LOTS as medicine that everybody else gets. Doctors do not buy cheap medicine to treat minorities and then buy expensive medicine for whites. They buy whatever medicine that they can afford to get their hands on to treat whoever needs it. They do not order medicine specifically for Whites, Blacks, or Asians.

      And when it comes to infected blood, ANYBODY could get it. All of the blood goes through the same screening processes, and is subjected to the same scruitiny and standards as every other pint of blood. The only time blood is segregated is when it is screened for diseases, and classified by blood type: A, B, AB, O, etc.

      I have yet to see a bucket of old, expired medicine, dirty syringes, and out-of-spec blood that says "COLORED" and a box of fresh, new medicine, sterile syringes and clean blood that says "WHITES ONLY".

      Nice try with the racism angle. Take that crap somewhere else.

      --
      Knowing Google's lust for data collection, the Soviet Union is still alive and well inside the psyche of Sergey Brin....
    3. Re:Lots of benifets beyond medical necessity by Peyna · · Score: 1

      I think the OP's point was that certain people do not trust the blood supply because they believe inferior medicine supplies are directed toward them, not that such practices have ever or still do occur. The distrust is the problem. Whether or not it actually happens is mostly irrelevant to the problem of people refusing treatment because they do not trust that they are receiving what they should be.

      Read posts before you respond to them next time.

      --
      What?
    4. Re:Lots of benifets beyond medical necessity by IHC+Navistar · · Score: 1

      I did.

      --
      Knowing Google's lust for data collection, the Soviet Union is still alive and well inside the psyche of Sergey Brin....
    5. Re:Lots of benifets beyond medical necessity by jfmiller · · Score: 1

      I can tell you that no matter what the ultimate decision, being caught between needing blood and keeping faith is a heart breaking and guilt ridden experience for doctors, patients and families.

      Yeah but for secular darwinists it's a laugh and a half. I promise you that not even an atheist physician is laughing when they have to be part of a decision like this. Even if you actively deny religion, telling someone they must choose between loosing their life and loosing all connection with their family and community it heart-breaking for anyone with even a shred of (possibly secular) humanity.
      --
      Strive to make your client happy, not necessarly give them what they ask for
    6. Re:Lots of benifets beyond medical necessity by jfmiller · · Score: 1

      There are some well documented cases of just such things having happened in the 50's and early sixties. I know for a fact that in is not the case in the Emergency Department I worked with, but there were still three cases in my three month CPE unit of patients refusing needed transfusions because they feared that they were getting "dirty blood."

      Racism is not just the extent of current actions, it is also the mistrust bread by past experience. This mistrust is compounded when one adds to it poverty, bureaucratic abuse, and mental illness that are common in the homeless population. This is not an angle. It is simply my reflection on the realities of life and death in our health system as I got to know it.

      --
      Strive to make your client happy, not necessarly give them what they ask for
    7. Re:Lots of benifets beyond medical necessity by Anonymous Coward · · Score: 0

      and others as divers as the Hmong

      Gee, I didn't realize that the Hmong were such underwater diving fiends!

      (Try "diverse")

  49. Celebrities of the World - rejoice! by Shemmie · · Score: 2, Funny

    Now not only can your noses, your breasts, your pecks and so forth be plastic, but your blood can be plastic too!
    "Plastic to the core, baby!"

  50. Not in this fashion. by Upaut · · Score: 1

    This is 100% artificial blood, not a blood derived from animal blood. The best artificial blood? Modified horse. The one you mentioned? Bovine.

    Do "I" care either way? Nope. I have a rare blood type and would accept anything.

    But people with some religions do. Hindu's would not accept the bovine derived blood, and the Jehovia's witnesses wouldn't accept any form of blood derived from another's blood.

    If the JW accept this product, then fewer of them will die in surgery, or have their children die. Fewer deaths all around is always a good thing in my book.

    --
    3 degrees of separation from Vladimir Putin
    1. Re:Not in this fashion. by Anonymous Coward · · Score: 0

      "If the JW accept this product, then fewer of them will die in surgery, or have their children die. Fewer deaths all around is always a good thing in my book."

      Yeah I guess, but we're talking about Jehovah's Witnesses...

  51. SangKa by Anne_Nonymous · · Score: 1

    >> a sort of artificial blood substitute

    <Mr. Announcer Voice> We've replaced Bob's regular blood with new SangKa blood substitute. Let's see if he notices... </Mr. Announcer Voice>

  52. Question for those who tried already by Kaitnieks · · Score: 1

    Does it taste as good as the real blood if you're a vampire?

    1. Re:Question for those who tried already by Anonymous Coward · · Score: 1, Funny

      No

  53. Not the first time by akac · · Score: 1

    I've been reading artificial blood articles on Slashdot for 5 years now. Maybe longer. The title reads as if its the first time. Just mentioning..

  54. My memory on this is vague. by xerxesVII · · Score: 2, Interesting

    I seem to recall reading about an emergency blood substitute in the late 90s. The odd thing about it was that it wasn't red, but white. There was a picture of a lab rat (albino, of course) that had a complete transfusion and its eyes were silver. Does anyone else remember this?

    --
    "We shall grapple with the ineffable, and see if we may not eff it after all." - Douglas Adams
    1. Re:My memory on this is vague. by Anonymous Coward · · Score: 0

      I seem to recall something on "That's incredible!" in the early 80s, with a rhesus monkey getting a complete transfusion with a blood substitute on the show. Poor damned thing could barely move afterwords.

  55. Get in line... by PurpleCarrot · · Score: 1

    Not the first time; see this press release from 2006: http://www.kumc.edu/news/publish/article_00818.sht ml

  56. Suuuuuure..... by cakeypower · · Score: 1

    ...they did... whats next and artificial heart? LOL

  57. Reminds me of Neuromancer... by MaineCoon · · Score: 1

    "Enjoy your cheap plastic replacement!"

    --
    Hunt your preferred prey at Aliens vs Predator MUD. Join the war at avpmud.com port 4000
  58. Difficult Road.... by MedBob · · Score: 0

    As a Blood Banker... There have been many many attempts to create a replacement for banked blood. All of these have failed when tested on a biological model. Many have produced kidney damage in animal models, and many others simply did not work. This particular version is very early in it's development.
    When it can keep a dog alive.... then call me.

  59. Dissolving Sutures by camperdave · · Score: 1

    Perhaps They could make the artificial blood out of the same sort of material that they use for dissolving sutures. Your red blood cell count usually takes a couple of weeks to come back to normal after a serious bleed. So as the artificial blood dissolves, brand new natural red blood cells take over.

    --
    When our name is on the back of your car, we're behind you all the way!
  60. Vampires by Anonymous Coward · · Score: 0

    There actually is a series where vampires 'came out' to the world once a synthetic blood substitute that could support them was developed. It's the Southern Vampire series by Charlaine Harris and is rather good.

  61. Are you so sure they haven't started testing? by slew · · Score: 1

    Soo... why is this news when there hasn't even been animal testing yet?
    I'm not so sure this is very different than PolyHeme which is artifical blood made with polymerized human haemoglobin extracted from expired donated blood.

    Eventually PolyHeme was tested on humans using an opt-out technique (if you didn't have a special bracelet on your wrist, they could use PolyHeme instead of real blood in trama situations where you couldn't object to being a test subject). As you might imagine, medical testing using an unpublicized opt-out scheme was very controversial at the time.

  62. Re:Friday First Post!!1! by Anonymous Coward · · Score: 0
  63. haemoglobin? by eXFeLoN · · Score: 0

    I for one welcome our iron nucleied plastic fake blood jaemoglobin overlords.. Is there no open source text editing / word processing software that has a spellchecker? I say this because no full blooded (hah) poster would dare use a word processor that had to be paid for....

    --
    My other sig is a knife wound.
  64. All day and all of the night by Dogtanian · · Score: 2, Funny

    Nah, I'll stick with natural. This artificial stuff tastes too much like plastic If this takes off, all the vampires'll be going around trying to figure out which humans are "organic" and which have the plastic stuff in their blood. You can't tell just by looking. Hey!..... I know a song about that.

    # A man lives at the corner of the street,
    And his neighbors think he's helpful and he's sweet,
    'Cause he never swears and he always shakes you by the hand,
    But no one knows he really is a plastic man. #

    # He's got plastic heart, plastic blood and veins
    (Yeah, he's plastic man)
    He's got plastic knees and [eh, sod this I can't make it rhyme and Ray Davis is going to sue me]. #
    --
    "Slashdot - News and Chat Sites Deviant". (Click "homepage" link above for details).
  65. Yes, but is it thicker than artificial water? by Nibbler999 · · Score: 1

    IMWTK

  66. hmm... PurBlood anybody? by blankmange · · Score: 2, Interesting

    How is it Preston & Child wrote about this stuff years ago? If you read "Mount Dragon", you got a creepy feeling when you read the BBC article...

    --
    ...we are from the government - we are here to help...
  67. I want it purple! by ghostbar38 · · Score: 1

    Now I could be from loyalty :)

    --
    ghostbar page.
  68. Artificial blood? by dbk25 · · Score: 1

    Interestingly, it's also high in lycopene, works well on French Fries, and according to the package comes in 57 varieties.

  69. But, but... by Master+of+Transhuman · · Score: 1


    "The blood is the life, Mr. Renfield!"

    --
    Richard Steven Hack - This sig is TOO GODDAMN SHORT TO DO ANYTHING USEFUL WITH! MORONS!
  70. Brilliant! by SEWilco · · Score: 1

    "The substance is light"
    Patients will be in glowing health.

  71. Not so new, but what's new about that? by tkdog · · Score: 1

    This isn't really news. There has been gradual progress towards artificial blood products for years. It will be a great thing when it is widely available. Blood banks are expensive, difficult to manage and carry hazards of their own (disease, mismatching).

  72. It's just a fekki BBC story as in ... errrm "story by Carson+Napier · · Score: 1

    If you follow the link it leads to a short BBC story akin to pub draught conversation.... cheers!

    --
    If I wanted my mind made up for me, I'd do it myself!!
  73. SCAB by tate-o · · Score: 1

    Did anyone else notice the acronym of the headline? sorry, tate

  74. Half-uncial t by tepples · · Score: 1

    Really? I thought it was the lower-case letter T? Fear of crosses is why some vampires write lowercase t as a rounded L-shape with a line over it.
  75. I guess its a comfort thing by NouvelleChimie · · Score: 1

    I don't think the iron can get oxidized... if you look at a heme molecule, its complexed with all kinds of ligands I think we just studied this in class, but not in depth...so I don't know if oxygen could come snap off the ligands and rust it up.

    --
    Analytical chemists do it with fancy and expensive toys
    1. Re:I guess its a comfort thing by thePowerOfGrayskull · · Score: 1

      It was a joke -- well, the rusting part of it was, anyway

  76. got cyborgs? by OrangeTide · · Score: 1

    I know if I had a choice between dying from a massive wound or getting pumped full of cyborg blood I'd take the blood. what's the worse that could happen? I might die a little later from some complication, it's a fair deal.

    Now what if we have artificial blood that was better than the real thing and athletes started using it for a performance boost?

    --
    “Common sense is not so common.” — Voltaire
  77. dope by p3ns4 · · Score: 1

    I'm sure these developments make up for a new and interesting twist in the current doping bruhaha in endurance sports, i.e., pro cycling...

  78. Jehovah's Witness Compatible? by cephal0p0d · · Score: 1

    For Jehovah's Witnesses, blood transfusions are forbidden, as they percieve it as 'consuming' blood.
    A no-no according to some scripture or other.

    I wonder if they can use this new syntheglobin stuff.

    --


    ~!J!
    1. Re:Jehovah's Witness Compatible? by Datamonstar · · Score: 1

      Actually, I would suspect that some Witnesses would be hesitant to receive such a transfusion without a thorough understanding of exactly what is involved. After-all, the reasons for refusing blood are based on respect for God's view on the sanctity of blood, not the simple fact that it is, as you put it, a "no-no."

      --
      The eternal struggle of good vs. evil begins within one's self.
  79. Cost of Artificial blood for your cat? by Nivag064 · · Score: 1

    How much did it cost to save your cat's life?

  80. How much to save your cat? by Nivag064 · · Score: 1

    I am curious, how much did it cost to save your cat?

  81. Sorry my browser crashed! by Nivag064 · · Score: 1

    My browser gave me the impression that it had not posted the comment...