I did some genetics research -early stuff on the genome project. When I first started, some results didn't make sense, and my boss said- "Oh, that's the milkman gene"
I tried to remember what that gene did, until I figured out what he meant.
Do you really want to find out that Dad isn't your father?
But we now know that it's not true. There is a class G star (like our own Suns class) only 5 light years away - a mere 50 years traveling at 10% C (it'll take about 34 days accelerating at a constant 1 G to reach 10% C).
There are 50 star systems (66 stars because of several binary systems) within 16 light years of earth. 50 of these stars are M class or red in color - about 80% of these are red dwarfs - probably not a great place to look for habitable planets.
It should be a fairly attainable goal to send out 20 ships to the 10 most likely close habitable stars, and expect to see a result in 60 or so years (50 years travelling + 10 years for radio message to be sent back)
Your gadgets, possessions do not make you as a person. They only tie you down, worrying about if they break, get stolen, etc. After a while your possessions can "own" you, with you worrying about them, taking time for them. Having said that, I'll admit to being a little hypocritical, as I own a Porsche, and yes I do think about taking it to the really crappy parts of town (is someone going to ding the door, etc.) As for everything else, I try to not buy anything that I would worry about. If I lose it/have it stolen/ break it, then it shouldn't matter to me.
This philosophy will free you up, and keep you at ease.
I often thought that maybe it used part of his bodies own interstitial fluid as part of a binary mixture. That way when Spiderman uses a lot of webbing, he becomes dehydrated, and just needs to drink more.
98-99% obese people do NOT have genetic causes
on
Treadmill Workstation
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· Score: 1
Pobably less than 1% of overweight peoople have some sort of genetic condition/hormonal problem that causes them to be overweight. Almost all familial obesity is from learned behavior, and from being a fat kid (fat cells tend not to die off).
The New England Journal of Medicine (NEJM) had an article were they looked at obese and thin people and the amount of food and exercise they did. The obese people tended to underestimate the amount of food they ate by half!, and overestimated the amount of exercise they did by twice!. This was a well designed study - randomized groups, etc, and the conclusions were significant (p0.05) in that the study groups (obese vs thin) had differing amounts of food and exercise.
Anecdotal information - my friends mom (overweight) always joked about me (skinny) having a hollow leg, and remarked that she could never eat as much food as I could. However, the big meal that I ate was often the only meal I'd eat during the day, while I often saw her snacking though out the day.
People do have differing basal metabolic rates (BMR), which is usually a function of how much muscle mass they have, among other things. So people with a higher BMR burn more calories a day do to their higher needs (think car engines - a V8 uses more than a 4 cylinder engine). Thus the people with the higher BMR can eat more and not gain weight.
Obese people usually have poor nutrition (Significantly lower blood albumen levels) than thinner people. The relatively decreased muscle mass also makes it more difficult to exercise, since the poor muscle get overworked too easily, and they can't exercise enough(hard to lug a boat up a hill with a Honda Accord).
William Gibson had made a remark about computers and the hard drive, and he was fascinated to learn that the hard drives had a moving platter. He then likened them to Victorian age record players.
Here's a Kaiser study - the$ billion dollar amount is only the R&D/FDA trial costs. What about when companies get sued by lawyers for billions of dollars for crap lawsuits - I.E. Dow chemical for silicone breast implants - bankrupted for no definite scientific evidence, and now people are using them again.
The Vioxx lawsuit is costing Merck between 4 and 30 billion$ for some shaky scientific evidence. There were perhaps 300-400 people who doctors though had deaths DIRECTLY contributable to Vioxx - now remind you , many of these patients had crippling arthritis, pre-existing cardiac conditions, were over 70 years of age. I've had patients tell me that they take up to 4-5 times the recommended doses of pain medicine sometimes. Do you think the lawyers, or clients mention that - of course not - they want their easy money. Do you think many of those people would have died anyway? - probably.
IF you are involved in medicine, and have some money, you will get sued. Every doctor and pharmaceutical company does, and the cost gets passed on to everyone else in the form of a 65 cent pill, as opposed to a 30 cent pill. THese class action lawsuits make multi millions for many law firms, because enough people in menial jobs don't want to work anymore , and are "injured, or think they are" (actual line I heard from an ambulance chaser commercial).
These countries are treading on a slippery slope. At what point is it OK now to not pay for the hard work of other people, or to begin to directly steal from them? If this happens enough the company will go bankrupt as correctly pointed out by the parent comment. There will always be someone else who can justify why their need is to get/steal/borrow what they need to a greater and greater extent. Yes I know that giant pharm firms spend a lot on advertising, but it also costs approximately one Billion dollars to get a single new drug to the marketplace (that's $1,000,000,000 !!)
Pricing is a problem for the third world countries, probably because it takes so many resources to make that product. Now please pay attention - I'm not saying that Brazil is unjustified in it's taking of the drug and helping those people, but rather that there needs to be some limits so that this behavior is not abused, and ruins it for everyone. This sounds like a good problem for the U.N.
Although by the time it would probably take you to read this, Chuck has already delived a kick from "Law" his left leg, propelling you into the afterlife - a second kick from his right leg "Order" will not be necessary. How is heaven treating you?
Oxygen consumption total =same over lifespan
on
Longevity Gene Found
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· Score: 1
Someone I had worked with at the National Institutes of Health had looked in to those starvation diets, and saw that the animnals total oxygen use, be it the starved rat, or non-starved rat, were roughly the same at the end of their life. The fatter rats just used theirs up faster.
Remember, oxygen is a fairly corrosive molecule, and is not necessarily good for you.
Just ask the 12 inch guitar player - he'll know where to find it. But he's probably looking for a 1 inch guitar string to play ulta tiny mario brothers.
I bought an iPod and liked it sooo much got one for the wife. She then after liking the device so much, became tired of the "crazy damned computer" that I set up for her that ran Linux, and bought a Mac laptop.
My wife still has some problems, but seems quite happy so far.
So yes, in our case, buying an iPod led us to buy a Mac.
I basically keep my wrist still and throw/slap my finger forward - it make a nice clapping sound. It always screw up people who have poised that question in front of me.
It will be a learning experience, and it will make him more independent. He can then install whatever OS he wants too - XP or Linux or BSD, etc. Usually many places sell barebones systems, and all he'd have to do would be to get a sound card (maybe - many motherboards have pretty good sound now), a monitor, and maybe a video card.
Using a power source like this would be a great boon to any medical devices that currently run off batteries - i.e. pacemakers, infusion pumps,cochlear implants etc. Hell, you could use it to power via induction external gadgets - your cellphone, watch, computer wireless modem, heck - internal computer with computer terminal glasses, etc.
Build in a failsafe so that it doesn't reduce your blood sugar to below a critical level, so that you don't go into a hypoglycemic shock, and you're good to go. This would be really useful to diabetics to maintain their constant blood sugar level at a more physiologic normal value. "Crap - my blood glucose is 250. Anyone need their phone charged?"
People with ALS (Amyotrophic Lateral Sclerosis, or Lou Gehrigs disease) usually die when their diaphragm and chest wall muscles are too weak to provide force for breathing. Roughly 1/2 die in the first year after diagnosis, and the remaining 50% exhibit a mortality curve with a long, scewed tail. About 1 in 5 survive 5 years and 1 in 10 survive 10 years.
Having said that, Sir(?) Hawking probably has many resources not cheaply available to most - 24 hr nursing care so he doesn't get bed sores, etc.
It's hard to make blanket statements about genetic diseases, since the morbidity and mortality vary so much. But in general, the more information you have about it, will let you make your choices more rationally.
I can see the tuner crowd now looking for 2 photon chips, although on a side thought, all of the computer interior neon lighting might have to go, since it "might" interfere with the photonic core - lol
Anonymous Coward on Tuesday March 13, @10:01PM People can still be fat and "in shape", or thin - it just matters if your heart is used to exercising.
The New England Journal of Medicine looked at obese and thin people about 7 years ago and compared their eating/exercise habits. The overweight people typically underestimated the amount of food they ate by 1/2 and overestimated the amount of exercise they did by two times.
Weight is basically a function of how many calories you consume. Two people can eat the same amount of food and maintain their bodyweight, whether it is 300 or 120 pounds. As long as you are not eating more calories than your basal metabolic rate, you should stay the same weight. Thus the overweight person eating salad complaining they never lose weight. A pound of fat is equivalent to 3500 calories. The average caloric intake on a 150 pound person is about 2500 calories, the amount of calories a 150 pound person would use by walking/running a marathon is about 3700 calories. Thus exercise is not the main contributing factor to weight lose/gain - it's food intake, or lack thereof.
Indigenous American Indians used to catch horses by outrunning them, until the horse was too tired to run anymore. If one trains a horse to run long distances, then I don't know, but a typical wild horse is not much of a match against a determined, trained human in terms of distance. So I guess both the parent and grandparent messages are correct.
More and more governments don't like proprietary or closed formats for documents. HP always seems to be able to get big government computer contracts, so this seems like an easy route to follow.
I know you can get performance improvement from overclocking, although the CPU usually isn't the bottleneck in performance for most computers. My point was that most people will probably be doing this for show (i.e. giant spoiler, air dam, and fart pipe muffler on their car with little/no improvement in performance), and that the "overheating" of their memory is a minimal risk if their systems has adequate ventilation. I previously installed water cooling on my system, but more for noise reduction.
As far as cars go, I've replaced entire engines, dropped trannies, etc so STFU before making any assumptions about me in your condescending reply. My overall point is that, for most people, it will produce little benefit, and that most who do it will not need it. How many cars have you seen with 50-75 extra pounds of side skirts, spoilers and splitters, low profile rims, dropped suspension, etc -who never ever take their car to the track? It's for show -the extra weight decreases their HP/to weight ratio, fart pipes drops their low end torque, super low profile tires increases their unsprung weight, and dropped stiffer suspension will increase their over/under steer depending on their weight ratio. Yes all that stuff is useful when done for the right reason, but MOST people will not need it.
Maybe most movies occur in a place where the majority of buildings and cars gastanks are made of flint and the bullets are made of steel = instant fun.
Marginal improvement in performance, with the possibility of doing serious harm to your system. This stuff also reminds me of the 100 MPG "vortex" air fans that you put into your car to improve it's mileage, or guys buying big rims for their cars.
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I did some genetics research -early stuff on the genome project. When I first started, some results didn't make sense, and my boss said- "Oh, that's the milkman gene"
I tried to remember what that gene did, until I figured out what he meant.
Do you really want to find out that Dad isn't your father?
at 10% C relatavistic problems should be minimal.
But we now know that it's not true. There is a class G star (like our own Suns class) only 5 light years away - a mere 50 years traveling at 10% C (it'll take about 34 days accelerating at a constant 1 G to reach 10% C).
There are 50 star systems (66 stars because of several binary systems) within 16 light years of earth. 50 of these stars are M class or red in color - about 80% of these are red dwarfs - probably not a great place to look for habitable planets.
It should be a fairly attainable goal to send out 20 ships to the 10 most likely close habitable stars, and expect to see a result in 60 or so years (50 years travelling + 10 years for radio message to be sent back)
Your gadgets, possessions do not make you as a person. They only tie you down, worrying about if they break, get stolen, etc. After a while your possessions can "own" you, with you worrying about them, taking time for them.
Having said that, I'll admit to being a little hypocritical, as I own a Porsche, and yes I do think about taking it to the really crappy parts of town (is someone going to ding the door, etc.) As for everything else, I try to not buy anything that I would worry about. If I lose it/have it stolen/ break it, then it shouldn't matter to me.
This philosophy will free you up, and keep you at ease.
I often thought that maybe it used part of his bodies own interstitial fluid as part of a binary mixture. That way when Spiderman uses a lot of webbing, he becomes dehydrated, and just needs to drink more.
Pobably less than 1% of overweight peoople have some sort of genetic condition/hormonal problem that causes them to be overweight. Almost all familial obesity is from learned behavior, and from being a fat kid (fat cells tend not to die off).
The New England Journal of Medicine (NEJM) had an article were they looked at obese and thin people and the amount of food and exercise they did. The obese people tended to underestimate the amount of food they ate by half!, and overestimated the amount of exercise they did by twice!. This was a well designed study - randomized groups, etc, and the conclusions were significant (p0.05) in that the study groups (obese vs thin) had differing amounts of food and exercise.
Anecdotal information - my friends mom (overweight) always joked about me (skinny) having a hollow leg, and remarked that she could never eat as much food as I could. However, the big meal that I ate was often the only meal I'd eat during the day, while I often saw her snacking though out the day.
People do have differing basal metabolic rates (BMR), which is usually a function of how much muscle mass they have, among other things. So people with a higher BMR burn more calories a day do to their higher needs (think car engines - a V8 uses more than a 4 cylinder engine). Thus the people with the higher BMR can eat more and not gain weight.
Obese people usually have poor nutrition (Significantly lower blood albumen levels) than thinner people. The relatively decreased muscle mass also makes it more difficult to exercise, since the poor muscle get overworked too easily, and they can't exercise enough(hard to lug a boat up a hill with a Honda Accord).
William Gibson had made a remark about computers and the hard drive, and he was fascinated to learn that the hard drives had a moving platter. He then likened them to Victorian age record players.
Here's a Kaiser study - the$ billion dollar amount is only the R&D /FDA trial costs. What about when companies get sued by lawyers for billions of dollars for crap lawsuits - I.E. Dow chemical for silicone breast implants - bankrupted for no definite scientific evidence, and now people are using them again.
d ex.cfm?DR_ID=17747
The Vioxx lawsuit is costing Merck between 4 and 30 billion$ for some shaky scientific evidence. There were perhaps 300-400 people who doctors though had deaths DIRECTLY contributable to Vioxx - now remind you , many of these patients had crippling arthritis, pre-existing cardiac conditions, were over 70 years of age. I've had patients tell me that they take up to 4-5 times the recommended doses of pain medicine sometimes. Do you think the lawyers, or clients mention that - of course not - they want their easy money. Do you think many of those people would have died anyway? - probably.
IF you are involved in medicine, and have some money, you will get sued. Every doctor and pharmaceutical company does, and the cost gets passed on to everyone else in the form of a 65 cent pill, as opposed to a 30 cent pill. THese class action lawsuits make multi millions for many law firms, because enough people in menial jobs don't want to work anymore , and are "injured, or think they are" (actual line I heard from an ambulance chaser commercial).
Link to Kaiser/Tufts study supporting the billion dollar R&D/FDA cost per new drug below.
http://www.kaisernetwork.org/daily_reports/rep_in
Study from Tufts
e wsid=6
d ex.cfm?DR_ID=17747
http://csdd.tufts.edu/NewsEvents/RecentNews.asp?n
Kaiser study
http://www.kaisernetwork.org/daily_reports/rep_in
These countries are treading on a slippery slope. At what point is it OK now to not pay for the hard work of other people, or to begin to directly steal from them? If this happens enough the company will go bankrupt as correctly pointed out by the parent comment. There will always be someone else who can justify why their need is to get/steal/borrow what they need to a greater and greater extent.
Yes I know that giant pharm firms spend a lot on advertising, but it also costs approximately one Billion dollars to get a single new drug to the marketplace (that's $1,000,000,000 !!)
Pricing is a problem for the third world countries, probably because it takes so many resources to make that product.
Now please pay attention - I'm not saying that Brazil is unjustified in it's taking of the drug and helping those people, but rather that there needs to be some limits so that this behavior is not abused, and ruins it for everyone. This sounds like a good problem for the U.N.
Although by the time it would probably take you to read this, Chuck has already delived a kick from "Law" his left leg, propelling you into the afterlife - a second kick from his right leg "Order" will not be necessary. How is heaven treating you?
Someone I had worked with at the National Institutes of Health had looked in to those starvation diets, and saw that the animnals total oxygen use, be it the starved rat, or non-starved rat, were roughly the same at the end of their life. The fatter rats just used theirs up faster.
Remember, oxygen is a fairly corrosive molecule, and is not necessarily good for you.
Just ask the 12 inch guitar player - he'll know where to find it. But he's probably looking for a 1 inch guitar string to play ulta tiny mario brothers.
I bought an iPod and liked it sooo much got one for the wife. She then after liking the device so much, became tired of the "crazy damned computer" that I set up for her that ran Linux, and bought a Mac laptop.
My wife still has some problems, but seems quite happy so far.
So yes, in our case, buying an iPod led us to buy a Mac.
I basically keep my wrist still and throw/slap my finger forward - it make a nice clapping sound. It always screw up people who have poised that question in front of me.
It will be a learning experience, and it will make him more independent. He can then install whatever OS he wants too - XP or Linux or BSD, etc. Usually many places sell barebones systems, and all he'd have to do would be to get a sound card (maybe - many motherboards have pretty good sound now), a monitor, and maybe a video card.
Using a power source like this would be a great boon to any medical devices that currently run off batteries - i.e. pacemakers, infusion pumps,cochlear implants etc. Hell, you could use it to power via induction external gadgets - your cellphone, watch, computer wireless modem, heck - internal computer with computer terminal glasses, etc.
Build in a failsafe so that it doesn't reduce your blood sugar to below a critical level, so that you don't go into a hypoglycemic shock, and you're good to go. This would be really useful to diabetics to maintain their constant blood sugar level at a more physiologic normal value. "Crap - my blood glucose is 250. Anyone need their phone charged?"
People with ALS (Amyotrophic Lateral Sclerosis, or Lou Gehrigs disease) usually die when their diaphragm and chest wall muscles are too weak to provide force for breathing. Roughly 1/2 die in the first year after diagnosis, and the remaining 50% exhibit a mortality curve with a long, scewed tail. About 1 in 5 survive 5 years and 1 in 10 survive 10 years.
Having said that, Sir(?) Hawking probably has many resources not cheaply available to most - 24 hr nursing care so he doesn't get bed sores, etc.
It's hard to make blanket statements about genetic diseases, since the morbidity and mortality vary so much. But in general, the more information you have about it, will let you make your choices more rationally.
I can see the tuner crowd now looking for 2 photon chips, although on a side thought, all of the computer interior neon lighting might have to go, since it "might" interfere with the photonic core - lol
Anonymous Coward on Tuesday March 13, @10:01PM
People can still be fat and "in shape", or thin - it just matters if your heart is used to exercising.
The New England Journal of Medicine looked at obese and thin people about 7 years ago and compared their eating/exercise habits. The overweight people typically underestimated the amount of food they ate by 1/2 and overestimated the amount of exercise they did by two times.
Weight is basically a function of how many calories you consume. Two people can eat the same amount of food and maintain their bodyweight, whether it is 300 or 120 pounds. As long as you are not eating more calories than your basal metabolic rate, you should stay the same weight. Thus the overweight person eating salad complaining they never lose weight.
A pound of fat is equivalent to 3500 calories. The average caloric intake on a 150 pound person is about 2500 calories, the amount of calories a 150 pound person would use by walking/running a marathon is about 3700 calories. Thus exercise is not the main contributing factor to weight lose/gain - it's food intake, or lack thereof.
Indigenous American Indians used to catch horses by outrunning them, until the horse was too tired to run anymore. If one trains a horse to run long distances, then I don't know, but a typical wild horse is not much of a match against a determined, trained human in terms of distance.
So I guess both the parent and grandparent messages are correct.
More and more governments don't like proprietary or closed formats for documents. HP always seems to be able to get big government computer contracts, so this seems like an easy route to follow.
I know you can get performance improvement from overclocking, although the CPU usually isn't the bottleneck in performance for most computers. My point was that most people will probably be doing this for show (i.e. giant spoiler, air dam, and fart pipe muffler on their car with little/no improvement in performance), and that the "overheating" of their memory is a minimal risk if their systems has adequate ventilation. I previously installed water cooling on my system, but more for noise reduction.
As far as cars go, I've replaced entire engines, dropped trannies, etc so STFU before making any assumptions about me in your condescending reply.
My overall point is that, for most people, it will produce little benefit, and that most who do it will not need it. How many cars have you seen with 50-75 extra pounds of side skirts, spoilers and splitters, low profile rims, dropped suspension, etc -who never ever take their car to the track? It's for show -the extra weight decreases their HP/to weight ratio, fart pipes drops their low end torque, super low profile tires increases their unsprung weight, and dropped stiffer suspension will increase their over/under steer depending on their weight ratio.
Yes all that stuff is useful when done for the right reason, but MOST people will not need it.
Maybe most movies occur in a place where the majority of buildings and cars gastanks are made of flint and the bullets are made of steel = instant fun.
Marginal improvement in performance, with the possibility of doing serious harm to your system. This stuff also reminds me of the 100 MPG "vortex" air fans that you put into your car to improve it's mileage, or guys buying big rims for their cars.