Though I imagine that the original poster has exhausted all his standard treatment options, it might also be worth mentioning the sort of 'precision medicine' that major cancer centres like Sloan-Kettering are now starting to do. The idea is to take a sample of the tumour and sequence all the genes in which mutations might make the cancer responsive to some specific treatment (perhaps a drug that would not normally be considered for that type of tumour). This can now be done very rapidly. If one of the genes comes up as positive for an 'actionable' mutation, then in some circumstances the patient may be offered a treatment that is intended to exploit the damaged gene to target the tumour (e.g., as part of a new type of clinical trial that runs across cancers of different types where individual cases happen to have mutations in the same gene). Further details, including contact information, are here:
Google's mapping products have been getting steadily worse for the last couple of years. On a phone, Maps 6 was the last great version, with My Maps and Latitude nicely integrated, half-decent offline caching, and sane road colouring (especially for, e.g., UK users). Now we have a dumbed-down app that's superficially prettier with the currently fashionable low-contrast look that's harder to read, poorer road colouring in various countries, Latitude swallowed by Google+, and My Maps pointlessly spun off into a separate app. The desktop version also has a trendier but largely poorer interface, and although the 'Classic' version remains for the moment, 'migrated' My Maps tracks and locations no longer work properly. Purely for offline use, the Nokia Here maps app is so much better it's embarrassing - on a phone, you can cache an entire country or US state in a form that's fully searchable and routable with turn by turn navigation, and doesn't expire.
If you remove the plugin manually it will be reinstalled with every update, and if the plugin is on your system browsers will find it an use it.
Windows versions of Java now come with a control panel applet that lets you turn off the browser plugin, and I think this setting persists when Java is updated.
Ask if they would consider eating radioactive food!
A scientifically inclined artist, Zoe Papadopoulou, had some fun with this idea in an exhibition at the Wellcome Collection in London a couple of years ago. Visitors were invited to eat 'yellow cake' which, while sharing a name with processed uranium ore, was actually a real cake made from edible but naturally slightly radioactive ingredients (enough to pick up on a Geiger counter):
I don't know exactly what she used - Carbon-14 is ubiquitous, of course, though hard to detect in small quantities, but the ingredients seem to include brazil nuts (which tend to concentrate environmental radium) and she might have added some 'Lo Salt' for the potassium-40.
You evidently don't actually use the advanced features of the Windows 7 Start Menu. There are good reasons that the full-screen Start menu is so maligned.
Neither is as good as the Classic Shell start menu, which works on both.
"A statue of the Roman half-goat, half-man god Pan - who was the Greeks' god of the wild - getting wild with a female goat (see above) has proven so NSFW (or, in this case, NSFM) that the British Museum has placed a parental advisory in the gallery where it will be on view as part of the upcoming exhibition 'Life and Death in Pompeii and Herculaneum.' The statue was excavated from beneath some 100 feet of Volcanic ash that enveloped the Villa of the Papyri, the residence of Julius Caesar's father-in-law Lucius Calpurnius Piso Caesoninus, on the slope Mount Vesuvius."
And a microSD slot? Where on earth would I get one of those cheaper?
It would be very interesting to run some double blind tests and ABX comparisons between a $50 Sansa player and the new Sony. 'Audiophiles' tend not to like these sorts of tests, for some reason...
when you open the latest gadget, it's black boxes, nothing that you can see working, or replace without just desoldering a chip.
Prof George knows this of course:
"All of these things in our home do seem to work most of the time and because they don't break we just get used to them. They have almost become like Black Boxes which never die. And when they do we throw them away and buy something new."
The Daily Telegraph, knowing its readership (traditionally rather conservative and not exactly in the first flush of their youth) has chosen to emphasise the 'young people are lost generation' angle, which is reflected in the summary. But the message she's putting across in the Christmas Lectures is much more positive - the talks are intended for a general audience, especially kids, and she wants to get them excited about using everyday technology in creative ways, in the spirit of the Maker community.
They're part of a series goes back to the time of Faraday, and has featured many eminent scientists (including several Nobel laureates). They've just been broadcast on national TV, as they have been since the 60s (I suspect quite a few of us who ended up being scientists in the UK got early inspiration from one or more of these lectures).
I can't help imagining a correlation was made from the large bat population (and guano) at Kitum Cave on Mt Elgin.
Yes, the EMBOMM article mentions this:
"This [the hollow tree] may have resulted in massive exposure to bats and have created a situation similar to the one described for Marburg virus for which transmission from bats to humans has occurred in caves occupied by large bat colonies."
(Kitum is one of the caves where Marburg, a virus from the same family as Ebola, has been transmitted).
Previously, they just had a probable index case. They've now done a followup field study that confirms this case and identifies a hollow tree where the kids used to play as a possible source of the infection - it contained a bat colony at the time. They didn't find evidence that other wild animals were infected, suggesting transmission directly from the bats rather than from other bushmeat. The paper is very readable and not paywalled:
Speaking as a 'print fan', I don't have a problem with adaptations in general, just adaptations done 'badly'. The BBC Radio version of LOTR from the 80s was excellent, but their attempt to do The Hobbit back in the 60s wasn't much good. There's much to enjoy in the Jackson films of LOTR, but the type of flaw that has blighted his version of The Hobbit was already there to a lesser extent in the previous trilogy - good actors saddled with a clunky script, silly additions to the plot, over-emphasised battles, crudely altered characters, cringeworthy attempts at humour, and a general lack of subtlety. An adaptation doesn't have to follow the source slavishly to be good (see Game of Thrones for a really intelligent treatment that frequently takes major liberties with the novels), but it has to preserve something of the spirit of the original to really work for those who love the books (not just the popcorn crowd).
Footnote, after all these years, having read the novels multiple times, once to my daughter before the films first came out, I just recently had an in-story epiphany. It always seemed curious and whimsical that Gandalf was so adamant about Bilbo being included in the quest. But think -- that simple decision set in motion a chain of events that after many years leads to the destruction of the One Ring -- something that probably could not have happened otherwise. How did Gandalf know?
There are hints about this in various places:
Gandalf to Frodo:
'Behind that there was something else at work, beyond any design of the Ring-maker. I can put it no plainer than by saying that Bilbo was _meant_ to find the Ring, and _not_ by its maker. In which case you also were _meant_ to have it. And that may be an encouraging thought.'
Gandalf on planning the quest of Erebor in the Shire:
'It was a strange business. I did no more than follow the lead of "chance", and made many mistakes on the way.'
Gandalf on Thrain's map and key:
'...I suddenly remembered the strange chance that had put them in my hands; and it began now to look less like chance'
Gandalf on his choice of Bilbo:
'I knew in my heart that Bibo must go with him, or the whole quest would be a failure - or, as I should say now, the far more important events by the way would not come to pass'
Gandalf on happening to meet Thorin at just the right time to set everything in motion:
'A chance-meeting, as we say in Middle-earth'.
I think all this implies that apparently random events are getting the occasional nudge from a Higher Power, and that Gandalf in particular (as a member of an 'angelic' order in accord with the Divine Plan, albeit limited by his human incarnation) is getting the odd subtle hint (more of a feeling rather than any sort of direct instruction) on how best to proceed with his mission.
He's not the only one. People are imprisoned on Cuba for all sorts of bizarre reasons, even when there's no evidence they've actually committed a crime. Read the shocking story here: http://www.washingtonpost.com/...
"Yet beyond monetary damages, the case has zero bearing on the modern technology industry, as both the MP3 music file format and the iPod itself have waned in popularity"
Wait, what? People no longer use MP3s? They don't buy iPods?
They've also technically got it backwards. Neither Apple nor Real were distributing mp3s, but DRM'd music files in other formats - mp3s were never targeted by Apple's countermeasures to Real's hack. Today it's actually possible to get most music in plain mp3 format from Amazon and other online retailers so, if anything, mp3 is now vastly more popular than before (at least as a legitimate distribution format).
So might as well get vinyl for the physical copy, and an mp3 (or ogg or flac) for a digital copy, and skip the CD.
Some labels are releasing material exactly this way, with vinyl and download as the only options. If you go for the vinyl, you often also get a download code included.
How much do you think a standard Hershey Bar (plain, 43g) should cost in $USD? Genuinely curious.
I'm no chocolate snob, but you couldn't pay me to eat that stuff. Who ever thought it would be a good idea to add sour milk to perfectly adequate chocolate? It tastes like they've mixed it with baby vomit. As an emergency measure, all cocoa intended for Hershey's production should be seized and used to establish a National Cocoa Reserve. Only manufacturers with a track record of selling an edible product (like Ghirardelli) would then be allowed to draw on it. Sound reasonable?
Here's what the pie is. The pie is a market. The pie is cuttable into unlimited slices. Who gets the pie, depends on if they get into the market. Getting into the market guarantees them a slice of the pie. This is why Google entered the market. Because of capitalism, gobbling up as much pie as possible is always desired, even if it's unnecessary and duplicates what's already out there a million times over.
I don't understand! Do you have a car analogy?
Also, does this mean no more free pie? Will google crack down on Youtube downloaders and ad blockers that already give naughty, naughty people most of the advantages of this service for free..?
Slashdot Mirror
Though I imagine that the original poster has exhausted all his standard treatment options, it might also be worth mentioning the sort of 'precision medicine' that major cancer centres like Sloan-Kettering are now starting to do. The idea is to take a sample of the tumour and sequence all the genes in which mutations might make the cancer responsive to some specific treatment (perhaps a drug that would not normally be considered for that type of tumour). This can now be done very rapidly. If one of the genes comes up as positive for an 'actionable' mutation, then in some circumstances the patient may be offered a treatment that is intended to exploit the damaged gene to target the tumour (e.g., as part of a new type of clinical trial that runs across cancers of different types where individual cases happen to have mutations in the same gene). Further details, including contact information, are here:
http://www.mskcc.org/blog/new-...
My best wishes to the poster and his family at this very difficult time.
Google's mapping products have been getting steadily worse for the last couple of years. On a phone, Maps 6 was the last great version, with My Maps and Latitude nicely integrated, half-decent offline caching, and sane road colouring (especially for, e.g., UK users). Now we have a dumbed-down app that's superficially prettier with the currently fashionable low-contrast look that's harder to read, poorer road colouring in various countries, Latitude swallowed by Google+, and My Maps pointlessly spun off into a separate app. The desktop version also has a trendier but largely poorer interface, and although the 'Classic' version remains for the moment, 'migrated' My Maps tracks and locations no longer work properly. Purely for offline use, the Nokia Here maps app is so much better it's embarrassing - on a phone, you can cache an entire country or US state in a form that's fully searchable and routable with turn by turn navigation, and doesn't expire.
But hey -- since it is a TV show all they need are some special effects and to put the "contestents" in a room somewhere.
https://en.wikipedia.org/wiki/...
At the time, the presenter joked that the sequel would be 'Space Cadets: Mission to Mars'...
If you remove the plugin manually it will be reinstalled with every update, and if the plugin is on your system browsers will find it an use it.
Windows versions of Java now come with a control panel applet that lets you turn off the browser plugin, and I think this setting persists when Java is updated.
Ask if they would consider eating radioactive food!
A scientifically inclined artist, Zoe Papadopoulou, had some fun with this idea in an exhibition at the Wellcome Collection in London a couple of years ago. Visitors were invited to eat 'yellow cake' which, while sharing a name with processed uranium ore, was actually a real cake made from edible but naturally slightly radioactive ingredients (enough to pick up on a Geiger counter):
http://zoeworks.co.uk/projects...
I don't know exactly what she used - Carbon-14 is ubiquitous, of course, though hard to detect in small quantities, but the ingredients seem to include brazil nuts (which tend to concentrate environmental radium) and she might have added some 'Lo Salt' for the potassium-40.
You evidently don't actually use the advanced features of the Windows 7 Start Menu. There are good reasons that the full-screen Start menu is so maligned.
Neither is as good as the Classic Shell start menu, which works on both.
... the oldest goatse in history.
They already found that: http://blogs.artinfo.com/artin...
"A statue of the Roman half-goat, half-man god Pan - who was the Greeks' god of the wild - getting wild with a female goat (see above) has proven so NSFW (or, in this case, NSFM) that the British Museum has placed a parental advisory in the gallery where it will be on view as part of the upcoming exhibition 'Life and Death in Pompeii and Herculaneum.' The statue was excavated from beneath some 100 feet of Volcanic ash that enveloped the Villa of the Papyri, the residence of Julius Caesar's father-in-law Lucius Calpurnius Piso Caesoninus, on the slope Mount Vesuvius."
He customodded a BT kb into his old glove, added tweezers and a fist bump 8bit sound chirp. What's not to love?
So, basically you're saying that you Love the Power Glove?
Philip K Dick was right after all - 'The Empire never ended'. King Felix!
"The sky was the perfect untroubled blue of a television screen, tuned to a dead channel." - Neil Gaiman, Neverwhere:
http://journal.neilgaiman.com/...
I used too be abel too, but sinse I turned the currant up too 11 I carnt thync strait enuf too spel my name.
And a microSD slot? Where on earth would I get one of those cheaper?
It would be very interesting to run some double blind tests and ABX comparisons between a $50 Sansa player and the new Sony. 'Audiophiles' tend not to like these sorts of tests, for some reason...
when you open the latest gadget, it's black boxes, nothing that you can see working, or replace without just desoldering a chip.
Prof George knows this of course:
"All of these things in our home do seem to work most of the time and because they don't break we just get used to them. They have almost become like Black Boxes which never die. And when they do we throw them away and buy something new."
The Daily Telegraph, knowing its readership (traditionally rather conservative and not exactly in the first flush of their youth) has chosen to emphasise the 'young people are lost generation' angle, which is reflected in the summary. But the message she's putting across in the Christmas Lectures is much more positive - the talks are intended for a general audience, especially kids, and she wants to get them excited about using everyday technology in creative ways, in the spirit of the Maker community.
Nice article here:
http://www.independent.co.uk/n...
If you have a UK IP address or VPN, the Lectures are available here:
http://www.bbc.co.uk/programme...
They're part of a series goes back to the time of Faraday, and has featured many eminent scientists (including several Nobel laureates). They've just been broadcast on national TV, as they have been since the 60s (I suspect quite a few of us who ended up being scientists in the UK got early inspiration from one or more of these lectures).
Since Prof George is (a) under 40 and (b) not a 'he', that seems rather unlikely: http://en.wikipedia.org/wiki/D...
I can't help imagining a correlation was made from the large bat population (and guano) at Kitum Cave on Mt Elgin.
Yes, the EMBOMM article mentions this:
"This [the hollow tree] may have resulted in massive exposure to bats and have created a situation similar to the one described for Marburg virus for which transmission from bats to humans has occurred in caves occupied by large bat colonies."
(Kitum is one of the caves where Marburg, a virus from the same family as Ebola, has been transmitted).
Previously, they just had a probable index case. They've now done a followup field study that confirms this case and identifies a hollow tree where the kids used to play as a possible source of the infection - it contained a bat colony at the time. They didn't find evidence that other wild animals were infected, suggesting transmission directly from the bats rather than from other bushmeat. The paper is very readable and not paywalled:
http://embomolmed.embopress.or...
Speaking as a 'print fan', I don't have a problem with adaptations in general, just adaptations done 'badly'. The BBC Radio version of LOTR from the 80s was excellent, but their attempt to do The Hobbit back in the 60s wasn't much good. There's much to enjoy in the Jackson films of LOTR, but the type of flaw that has blighted his version of The Hobbit was already there to a lesser extent in the previous trilogy - good actors saddled with a clunky script, silly additions to the plot, over-emphasised battles, crudely altered characters, cringeworthy attempts at humour, and a general lack of subtlety. An adaptation doesn't have to follow the source slavishly to be good (see Game of Thrones for a really intelligent treatment that frequently takes major liberties with the novels), but it has to preserve something of the spirit of the original to really work for those who love the books (not just the popcorn crowd).
Footnote, after all these years, having read the novels multiple times, once to my daughter before the films first came out, I just recently had an in-story epiphany. It always seemed curious and whimsical that Gandalf was so adamant about Bilbo being included in the quest. But think -- that simple decision set in motion a chain of events that after many years leads to the destruction of the One Ring -- something that probably could not have happened otherwise. How did Gandalf know?
There are hints about this in various places:
Gandalf to Frodo:
'Behind that there was something else at work, beyond any design of the Ring-maker. I can put it no plainer than by saying that Bilbo was _meant_ to find the Ring, and _not_ by its maker. In which case you also were _meant_ to have it. And that may be an encouraging thought.'
Gandalf on planning the quest of Erebor in the Shire:
'It was a strange business. I did no more than follow the lead of "chance", and made many mistakes on the way.'
Gandalf on Thrain's map and key:
'...I suddenly remembered the strange chance that had put them in my hands; and it began now to look less like chance'
Gandalf on his choice of Bilbo:
'I knew in my heart that Bibo must go with him, or the whole quest would be a failure - or, as I should say now, the far more important events by the way would not come to pass'
Gandalf on happening to meet Thorin at just the right time to set everything in motion:
'A chance-meeting, as we say in Middle-earth'.
I think all this implies that apparently random events are getting the occasional nudge from a Higher Power, and that Gandalf in particular (as a member of an 'angelic' order in accord with the Divine Plan, albeit limited by his human incarnation) is getting the odd subtle hint (more of a feeling rather than any sort of direct instruction) on how best to proceed with his mission.
WHY?
KHAAAAAAN!!
He's not the only one. People are imprisoned on Cuba for all sorts of bizarre reasons, even when there's no evidence they've actually committed a crime. Read the shocking story here: http://www.washingtonpost.com/...
"Yet beyond monetary damages, the case has zero bearing on the modern technology industry, as both the MP3 music file format and the iPod itself have waned in popularity"
Wait, what? People no longer use MP3s? They don't buy iPods?
They've also technically got it backwards. Neither Apple nor Real were distributing mp3s, but DRM'd music files in other formats - mp3s were never targeted by Apple's countermeasures to Real's hack. Today it's actually possible to get most music in plain mp3 format from Amazon and other online retailers so, if anything, mp3 is now vastly more popular than before (at least as a legitimate distribution format).
So might as well get vinyl for the physical copy, and an mp3 (or ogg or flac) for a digital copy, and skip the CD.
Some labels are releasing material exactly this way, with vinyl and download as the only options. If you go for the vinyl, you often also get a download code included.
Funny if he decides to auction it again next week.
This is just a ploy by CERN to divert our attention away from their clandestine plans to take over the world.
What, again?
How much do you think a standard Hershey Bar (plain, 43g) should cost in $USD? Genuinely curious.
I'm no chocolate snob, but you couldn't pay me to eat that stuff. Who ever thought it would be a good idea to add sour milk to perfectly adequate chocolate? It tastes like they've mixed it with baby vomit. As an emergency measure, all cocoa intended for Hershey's production should be seized and used to establish a National Cocoa Reserve. Only manufacturers with a track record of selling an edible product (like Ghirardelli) would then be allowed to draw on it. Sound reasonable?
Here's what the pie is. The pie is a market. The pie is cuttable into unlimited slices. Who gets the pie, depends on if they get into the market. Getting into the market guarantees them a slice of the pie. This is why Google entered the market. Because of capitalism, gobbling up as much pie as possible is always desired, even if it's unnecessary and duplicates what's already out there a million times over.
I don't understand! Do you have a car analogy?
Also, does this mean no more free pie? Will google crack down on Youtube downloaders and ad blockers that already give naughty, naughty people most of the advantages of this service for free..?