I haven't noticed any general slowness on an iPhone 5.
However, there does seem to be an issue with the new Control Center. I have noticed sluggish responsiveness from buttons on the bottom of the screen in certain apps, presumably due to a conflict with the Control Center which can be activated by an upwards swipe from the bottom of the screen. Turning off the Control Center within apps (Settings/Control Center/Access within apps) fixed this issue for me while still retaining functionality from the main and lock screens.
1) Yes, NEWSFLASH, technology has improved a lot in 50 years. Of course, not all light cars are more dangerous than heavier cars. However, if you take otherwise identical cars with the same level of technology, the heavier one is going to offer more protection in a collision (and/or is able to include more safety features within its weight limit).
It all depends on HOW you improve gas mileage. Faced with an arbitrary mandate like this, if car manufacturers are unable to meet these limits with new breakthroughs, they will most likely either reduce vehicle weight (with potential safety consequences) or create a few token expensive car models which will not really sell, but that have sufficiently improved gas mileage to bring up their average so that they don't have to change the majority of the fleet.
2) I wouldn't call 2.23x the MPG, 'almost triple'.:)
Wizard 101 is a good fit for that age group and very kid-safe. It has the added advantage that the base game is free (though you will have to pay to unlock later areas). Especially on the "free" areas, it is easy to create a second account and play at the same time as her.
Also agree with Portal/Baldur's Gate/Lego Star Wars,Harry Potter, etc / Zelda (Nintendo DS).
There are also the MySims' series of games. She may enjoy MySims Agents (I've only played on Wii)
As someone who performs helium-3 MRI on a regular basis, I can hopefully clear up a few things:
- Helium-3 MRI is a research-only technique
- The "veterinary use" is for animals in medical research, not taking "Fluffy" to the Vet.
- Before any recycled helium ever made it to humans, it would have to go through FDA-approved GMP processes. Given the enormous paperwork hassles involved, it is more likely that the recycled helium-3 would only ever be used in animals and in non-medical applications (e.g. low temperature physics).
- Just about everyone performing helium-3 MRI is trying to capture the exhaled gas whenever possible to conserve the supply. There is also a significant push to transition to the use of an isotope of Xenon gas. While Xenon-129 is much more abundant than helium-3, there are differences in its properties that make it better or worse suited for different experiments.
Tom's hardware does a best graphics card for the money every month with a breakdown for various pricing tiers. It also has a hierarchy chart that groups cards by performance levels, which helps to compare different models other than the "best" for each category.
As opposed to the last time CNN/MSNBC/NBC/ABC/CBS/PBS reported anything positive about a Republican? (Other than a story about a Republican that disagrees with the majority of other Republicans.)
he proposes the creation of a national "Change Congress" movement which would try to limit the influence of money in the electoral and legislative processes. Its a nice thought.
However, the only way to limit the influence of money (without gross violations of the First Amendment, etc) is to remove the reason people/corporations/interest groups pour money into the system in the first place. We have allowed the government to micromanage an increasing amount of our lives and activities, and this provides a strong incentive to try to influence the political process so that you don't get screwed (or so that the other guy gets screwed instead). If the government was actually kept limited to its constitutionally-granted powers and otherwise got out of our lives, you would see a lot of the money in politics dry up.
Additional Plusses: Actually it is a lot easier to make a low field magnet homogeneous than a high field. Also, the effect of many image artifacts will be significantly smaller (e.g. susceptibility gradients due to tissue interfaces).
Additional BIG negatives:
Signal to Noise - To a first approximation, the MRI signal strength is roughly proportional to the square of the magnetic field. While you can get some of that back by tweaking the experimental conditions, it will still boil down to either much longer imaging times or significantly lower resolution.
Contrast - The contrast in an MRI image is very dependent upon the magnetic field strength. At the field used in clinical scanners (usually 1.5 Tesla), the behaviors of different pathologies are extremely well known, which allows a diagnosis to be made. Even if the image quality is improved to the point where you could see something useful, it will take a lot of work before anyone knows how to actually interpret the images reliably for any serious work.
It is also worth mentioning that TFA is an (apparently) unpublished abstract, probably put together for the ISMRM (International Society for Magnetic Resonance in Medicine) conference next May (their submission deadline was last Wednesday).
That said, this does appear to be an impressive technical achievement and is worth pursuing... it just isn't going to revolutionize healthcare anytime soon.
Let me turn this around. If Claritin becomes Clarinex in the liver and Clarinex is the molecule that is actually having the desired effect on your body, then why would you want to expose yourself to Claritin in the first place (ignoring cost here)? The more different chemical entities that are in a drug or its metabolites, the more possibilities for side-effects and drug interactions.
Seriously, I'd like to see a reboot of Star Trek where they declare in one form or another that there is no longer any such thing as time travel,
Unfortunately, Paramount rejected the reboot of Star Trek that J. Michael Straczynski and Bryce Zabel pitched a few years ago. Since they were going to delete cheezy crap like holodecks, even if they did resort to time travel, I'd have to believe that they would have made sure it was well done. It's a shame this never got anywhere as it may have been the "last best hope" for the Star Trek franchise's future.
I just don't want the "bad guys" (terrorists, etc.) knowing my name is attached to anything that resulted in their cohorts arrested or killed on the battlefield
Perhaps. But, this was a graduate-level class designed for PhD students, not freshman biology. There is a different level of responsibility and maturity expected from students at this level, and in most other instances it was warranted.
Unfortunately, there does appear to be a cultural acceptance of cheating amongst the Chinese (at least by students). I ran into this during graduate school in the US. A large percentage of the students in my year were Chinese. For one class, we were given an individual, take-home, closed-book exam and a lot of us were working on it in the departmental library. A couple of the American students, myself included, observed two tables of Chinese students who were clearly discussing answers and referencing text books.
One other American student and myself went to complain to the department and were basically told: China has different views on cheating than we do, we are aware of the problem, and we grade on two separate curves based on this.
This seriously pissed me off and struck me as unfair not only to myself, but to any Chinese student who was honest enough to not cheat.
While I love FireFox and NoScript, they may not help you in this case. By default, NoScript allows yahoo.com and yimg.com to execute scripts, as they are required to actually read your email. So, even if you are using FireFox and NoScript you might still be vulnerable.
(Thankfully, I never received/opened that mail in my Yahoo account, so I don't know for sure).
While do-it-yourself solutions (new keyboards/mice, home exercises, wrist splints, etc) are a great first step, if you are still hurting don't be afraid to go to your doctor. They can run tests (e.g. EMG, blood flow studies) that can narrow down the problem and can prescribe physical therapy to help you through exercises specifically for your problem.
As a long-time RSI sufferer, it is also worth mentioning that even though the symptoms may appear in your wrist/hands, the actual problem could be in your shoulder or upper back. Impingements on the nerves or blood vessels in those locations can lead to symptoms further down their path. Posture and sleeping positions can be big culprits here.
Personally, I used to sleep on my stomach with an arm above my head and under the pillow. Changing sleeping positions went a long way towards relieving my symptoms, which were rooted in my shoulder and neck. Physical therapy and posture changes took me the rest of the way.
Actually, there are portable MRI systems http://www.mri4ra.com/ and they are not a safety hazard because a) their magnetic fields are 7x smaller than standard clinical MRIs and b) the field doesn't extend very far beyond the actual equipment.
These systems are typically designed for use on extremities and so would meet the request of the grandparent poster. However, the images are not nearly as good as a standard MRI for a few reasons:
1) To a first approximation, 7x smaller magnetic field means 49x lower S/N for the same imaging protocol and time. Now, you can get some of this back (~2-4x) by altering the protocol to take advantage of some differences caused by the smaller field. But typically, you acquire lower resolution images on these systems to compensate.
2) The magnetic field is less homogenious, so there are more distortions/artifacts in the images.
3) Because of some hardware compromises (and item 2 above), some MRI protocols are not possible on the portable systems.
So, for some highly specialized practices or isolated areas it might be a reasonable alternative, but for the majority of people it is not that useful.
Basically, you just perform the NMR experiment looking at deuterium and change the current to the shim electromagnets until you have maximized the peak height (thereby minimizing the linewidth). Alternately, you can look at the free-induction decay (FID) and attempt to find the exponentially decaying sinusoid with the longest time constant (which will result in the narrowest peak in the frequency domain). It is the same technique as when you use the proton signal.
The advantage of using the deuterium signal is that the deuterium molecules are only in the solvent (except for the very small natural abundance). This typically presents a simple spectrum (1-2 peaks) that is easy to optimize. Also, since the solvent molecules can move about and tumble freely on the timescale of the NMR experiment, any local interactions with other molecules are time averaged out and you are basically guaranteed to get a sharp, narrow line. If you use the proton signal, you can have multiplets and broad resonances which make it harder to find a good shim as you often have to determine if that extra peak is real or due to poor shimming.
Deuterium nuclei do have spin-1, which NMR is perfectly capable of detecting. In fact, many spectrometers use the deuterium NMR signal from deuterated solvents for shimming (compensating for magnetic field inhomogenieties typically introduced by the sample). Nuclei that have spin-0 (e.g. Calcium) are the ones that cannot be detected by NMR.
As an AC mentioned, the resonance frequency is different, so it just doesn't appear in the 1H NMR spectra. For example, on a commmon NMR spectrometer (7 Tesla), 1H (protons) resonate at 300 MHz and 2H (deuterium nuceli) resonate at 46 MHz.
Slashdot Mirror
I haven't noticed any general slowness on an iPhone 5.
However, there does seem to be an issue with the new Control Center. I have noticed sluggish responsiveness from buttons on the bottom of the screen in certain apps, presumably due to a conflict with the Control Center which can be activated by an upwards swipe from the bottom of the screen. Turning off the Control Center within apps (Settings/Control Center/Access within apps) fixed this issue for me while still retaining functionality from the main and lock screens.
1) Yes, NEWSFLASH, technology has improved a lot in 50 years. Of course, not all light cars are more dangerous than heavier cars. However, if you take otherwise identical cars with the same level of technology, the heavier one is going to offer more protection in a collision (and/or is able to include more safety features within its weight limit).
:)
It all depends on HOW you improve gas mileage. Faced with an arbitrary mandate like this, if car manufacturers are unable to meet these limits with new breakthroughs, they will most likely either reduce vehicle weight (with potential safety consequences) or create a few token expensive car models which will not really sell, but that have sufficiently improved gas mileage to bring up their average so that they don't have to change the majority of the fleet.
2) I wouldn't call 2.23x the MPG, 'almost triple'.
Why?
Because the easiest way to improve gas mileage is to reduce the weight of the vehicle, meaning less steel protecting you in an accident.
Wizard 101 is a good fit for that age group and very kid-safe. It has the added advantage that the base game is free (though you will have to pay to unlock later areas). Especially on the "free" areas, it is easy to create a second account and play at the same time as her.
Also agree with Portal/Baldur's Gate/Lego Star Wars,Harry Potter, etc / Zelda (Nintendo DS).
There are also the MySims' series of games. She may enjoy MySims Agents (I've only played on Wii)
As someone who performs helium-3 MRI on a regular basis, I can hopefully clear up a few things:
- Helium-3 MRI is a research-only technique
- The "veterinary use" is for animals in medical research, not taking "Fluffy" to the Vet.
- Before any recycled helium ever made it to humans, it would have to go through FDA-approved GMP processes. Given the enormous paperwork hassles involved, it is more likely that the recycled helium-3 would only ever be used in animals and in non-medical applications (e.g. low temperature physics).
- Just about everyone performing helium-3 MRI is trying to capture the exhaled gas whenever possible to conserve the supply. There is also a significant push to transition to the use of an isotope of Xenon gas. While Xenon-129 is much more abundant than helium-3, there are differences in its properties that make it better or worse suited for different experiments.
And instead of just saying "congratulations" and moving on, they have to keep gripping about how undeserved it is.
KEEP griping? It's only been what, 5 hours since the award was announced?
I think you meant the other 52 that superconduct, not 92.
Tom's hardware does a best graphics card for the money every month with a breakdown for various pricing tiers. It also has a hierarchy chart that groups cards by performance levels, which helps to compare different models other than the "best" for each category.
Here's the one for May. http://www.tomshardware.com/reviews/radeon-geforce-graphics,2296.html
As opposed to the last time CNN/MSNBC/NBC/ABC/CBS/PBS reported anything positive about a Republican? (Other than a story about a Republican that disagrees with the majority of other Republicans.)
In a related story, SETI@home users start receiving the message:
"Does this telescope make me look fat?"
However, the only way to limit the influence of money (without gross violations of the First Amendment, etc) is to remove the reason people/corporations/interest groups pour money into the system in the first place. We have allowed the government to micromanage an increasing amount of our lives and activities, and this provides a strong incentive to try to influence the political process so that you don't get screwed (or so that the other guy gets screwed instead). If the government was actually kept limited to its constitutionally-granted powers and otherwise got out of our lives, you would see a lot of the money in politics dry up.
Additional Plusses: Actually it is a lot easier to make a low field magnet homogeneous than a high field. Also, the effect of many image artifacts will be significantly smaller (e.g. susceptibility gradients due to tissue interfaces).
Additional BIG negatives:
Signal to Noise - To a first approximation, the MRI signal strength is roughly proportional to the square of the magnetic field. While you can get some of that back by tweaking the experimental conditions, it will still boil down to either much longer imaging times or significantly lower resolution.
Contrast - The contrast in an MRI image is very dependent upon the magnetic field strength. At the field used in clinical scanners (usually 1.5 Tesla), the behaviors of different pathologies are extremely well known, which allows a diagnosis to be made. Even if the image quality is improved to the point where you could see something useful, it will take a lot of work before anyone knows how to actually interpret the images reliably for any serious work.
It is also worth mentioning that TFA is an (apparently) unpublished abstract, probably put together for the ISMRM (International Society for Magnetic Resonance in Medicine) conference next May (their submission deadline was last Wednesday).
That said, this does appear to be an impressive technical achievement and is worth pursuing... it just isn't going to revolutionize healthcare anytime soon.
On the other hand, if you want to design a cannon that will destroy the moon, go to Caltech.
/
Or just go to MIT and steal it from Caltech
http://hacks.mit.edu/Hacks/by_year/2006/mitcannon
Let me turn this around. If Claritin becomes Clarinex in the liver and Clarinex is the molecule that is actually having the desired effect on your body, then why would you want to expose yourself to Claritin in the first place (ignoring cost here)? The more different chemical entities that are in a drug or its metabolites, the more possibilities for side-effects and drug interactions.
You can read about the reboot scroll halfway down this page in Zabel's blog http://bztv.typepad.com/newsviews/2006/06/spaced_
Perhaps. But, this was a graduate-level class designed for PhD students, not freshman biology. There is a different level of responsibility and maturity expected from students at this level, and in most other instances it was warranted.
Unfortunately, there does appear to be a cultural acceptance of cheating amongst the Chinese (at least by students). I ran into this during graduate school in the US. A large percentage of the students in my year were Chinese. For one class, we were given an individual, take-home, closed-book exam and a lot of us were working on it in the departmental library. A couple of the American students, myself included, observed two tables of Chinese students who were clearly discussing answers and referencing text books.
One other American student and myself went to complain to the department and were basically told: China has different views on cheating than we do, we are aware of the problem, and we grade on two separate curves based on this.
This seriously pissed me off and struck me as unfair not only to myself, but to any Chinese student who was honest enough to not cheat.
Well, it was called "Advanced Dungeons and Dragons 2nd Edition".
Remember a little game called Neverwinter Nights?
(Oh, and Baldur's Gate 2 was based off of 2nd Edition rules, not AD&D)
While I love FireFox and NoScript, they may not help you in this case. By default, NoScript allows yahoo.com and yimg.com to execute scripts, as they are required to actually read your email. So, even if you are using FireFox and NoScript you might still be vulnerable.
(Thankfully, I never received/opened that mail in my Yahoo account, so I don't know for sure).
While do-it-yourself solutions (new keyboards/mice, home exercises, wrist splints, etc) are a great first step, if you are still hurting don't be afraid to go to your doctor. They can run tests (e.g. EMG, blood flow studies) that can narrow down the problem and can prescribe physical therapy to help you through exercises specifically for your problem.
As a long-time RSI sufferer, it is also worth mentioning that even though the symptoms may appear in your wrist/hands, the actual problem could be in your shoulder or upper back. Impingements on the nerves or blood vessels in those locations can lead to symptoms further down their path. Posture and sleeping positions can be big culprits here.
Personally, I used to sleep on my stomach with an arm above my head and under the pillow. Changing sleeping positions went a long way towards relieving my symptoms, which were rooted in my shoulder and neck. Physical therapy and posture changes took me the rest of the way.
Actually, there are portable MRI systems http://www.mri4ra.com/ and they are not a safety hazard because a) their magnetic fields are 7x smaller than standard clinical MRIs and b) the field doesn't extend very far beyond the actual equipment.
These systems are typically designed for use on extremities and so would meet the request of the grandparent poster. However, the images are not nearly as good as a standard MRI for a few reasons:
1) To a first approximation, 7x smaller magnetic field means 49x lower S/N for the same imaging protocol and time. Now, you can get some of this back (~2-4x) by altering the protocol to take advantage of some differences caused by the smaller field. But typically, you acquire lower resolution images on these systems to compensate.
2) The magnetic field is less homogenious, so there are more distortions/artifacts in the images.
3) Because of some hardware compromises (and item 2 above), some MRI protocols are not possible on the portable systems.
So, for some highly specialized practices or isolated areas it might be a reasonable alternative, but for the majority of people it is not that useful.
Basically, you just perform the NMR experiment looking at deuterium and change the current to the shim electromagnets until you have maximized the peak height (thereby minimizing the linewidth). Alternately, you can look at the free-induction decay (FID) and attempt to find the exponentially decaying sinusoid with the longest time constant (which will result in the narrowest peak in the frequency domain). It is the same technique as when you use the proton signal.
The advantage of using the deuterium signal is that the deuterium molecules are only in the solvent (except for the very small natural abundance). This typically presents a simple spectrum (1-2 peaks) that is easy to optimize. Also, since the solvent molecules can move about and tumble freely on the timescale of the NMR experiment, any local interactions with other molecules are time averaged out and you are basically guaranteed to get a sharp, narrow line. If you use the proton signal, you can have multiplets and broad resonances which make it harder to find a good shim as you often have to determine if that extra peak is real or due to poor shimming.
Deuterium nuclei do have spin-1, which NMR is perfectly capable of detecting. In fact, many spectrometers use the deuterium NMR signal from deuterated solvents for shimming (compensating for magnetic field inhomogenieties typically introduced by the sample). Nuclei that have spin-0 (e.g. Calcium) are the ones that cannot be detected by NMR.
As an AC mentioned, the resonance frequency is different, so it just doesn't appear in the 1H NMR spectra. For example, on a commmon NMR spectrometer (7 Tesla), 1H (protons) resonate at 300 MHz and 2H (deuterium nuceli) resonate at 46 MHz.