If it's illegal to unlock the phone, that means I dont own it. Am I leasing it? How the hell else is it possible for me to outright purcahse something and not be able to do whetever the hell i want with it (besides to commit something that is already a crime obviously -like throwing it at someone).
If I buy a t-shirt can they make it illegal for me to use it as a rag?
Is it illegal to color the iphone with a marker? Is it illegal to open up the iphone and melt it down? Is it illegal to take the battery out of the iphone and use the large battery in a hobby RC car project? If it is, it damn well shouldn't be.
Wal-mart isn't forcing people to work at Chinese factories. People are choosing to work there instead of dying of starvation and preventable diseases on the farm. So it's work for walmart or die. I don't see how that's a choice. In fact, I'd call it coercion.
How is it coercion? They aren't the ones causing people to die. Think about it, without the factory.. the person wouldn't have a job at all. Walmart is not causing them to be poor. They would be poorer without Walmart. I mean, shit in that case i am being coerced to work too.. as is Bill Gates and Donald Trump. To make a coercion accusation, you have to show that Wal-mart created the horrible farming conditions. Good luck, because those conditions have existed for a long time (people in China as recently as 1950 had a life expectancy of under 40 years.. and infant mortality was very high).
If someone is willing to do work for you for less, why isn't it moral to choose that person? Because in this case, you'd be exploiting them by paying them wages less than the value of what they produce
Unless a person is being forced to work at gunpoint, that is impossible. Value of work is determined by supply and demand -- not anything intrinsic to the product. If there are others who are willing to provide a product for cheaper, I have the moral prerogative to choose the cheaper one provided by someone who is willing to work harder. The whole point of any work/pay contract is that the each person is choosing to work because they are going to be compensated equal to or more than what they feel the usefulness of their time/energy is. You can always choose not to work if you feel the deal is bad. So a doctor gives me a simple antibiotic and cures me of pneumonia so I live and can work.. by your logic, do I have to pay them my whole salary for life? After all, the value of the doctors work is my whole life. Obviously, if the doctor demanded that.. I would have chosen a different cheaper doctor.
If someone is willing to do work for you for less, why isn't it moral to choose that person?
The alternative to Wal-mart is people starving and dying like in Africa where there is hardly any industry.
Wal-mart isn't forcing people to work at Chinese factories. People are choosing to work there instead of dying of starvation and preventable diseases on the farm.
American workers can easily do other stuff instead of repetitive and boring factory jobs. Plus with the flood of cheap goods less work would be needed. Come on gardeners get paid $50 an hour. You think a factory worker would get anything beyond minimum wage? Also, we currently have a 5% unemployment rate here. Which jobs taht people are currently doing would they have to leave to fill up the shoe making factories? Are you prepared to give up cell phones and great computer software so that you can have shoes made by americans... americans who could have been designing technology instead?
The world still needs cures for major diseases. There aren't cheap cars of BMW quality. Ferrari performance is not available cheaply yet. Not everyone has a large house, there is mad demand fror pre-fabbed structures so that infrastructure to be built. All of this shows there is a need for products and services.. products and services the world wants.. that Americans can provide.
Do you think China has enough workers to construct all the machinery to develop their infrastructure? I don't think so.. there is already signs of labor shortage emerging in China..factories are having to provide beter and better incentives for their works (google china labor shortage ).. just to make products for export.
If someone is providing a service or item that people want, you shouldn't stand in the way of their transaction. After all, if you are replaced by robots would you still be indignant? The world is manufacturing crap for the US. The US should make things to exchange. Do you think the world wants to collect pieces of paper?? If they want to earn all this money, they are doing it because they too require services.
Instead of being pissed that others are making goods that people want to buy, there are plenty of things America can do to maintain its lead. People get paid for providing a useful service cheaper than others. If a service can be gotten for cheaper elsewhere, then a person should have the right to get it from elsewhere.. just like they have the right to refuse the service entirely.
Anyway, there are still things you can do to earn money:
1) Invent cures for diseases and slow down aging so that the life expectancy can be 120
2) Develop cheaper sources of energy that can be used to purify and distribute water to people who need it
3) Find out how to reduce crime to Japan's level, and then to one quarter of that. Then provide consulting to other countries.
4) Assist in building global infrastructure.. this can be in the form of fabricating things in the US and shipping them elsewhere. This is already done for airplanes etc. Most of the world is severely undeveloped and needs infrastructure. As long as people have a need for roads, sewers, and houses..this need is there.
There are simply not enough workers in the world to build all everything people need, so there will always be jobs.. until people have self contained in-home energy generators that manufactures happy pills and food from raw minerals. But at that point there would be no _need_ for jobs.
Multiple sclerosis is when your immune system attacks a nerve's covering called myelin. What the vaccine does is it gets the immune system to stop targetting the myelin by causing a reduction in the T-cells that attack it. If it works as they say, and have demonstrated, it only reduces the number of T-cells that target the myelin protein, not other stuff.
I think it's clear that the biggest threat to our existence as a species is our own selves, if we can't solve that problem how does going off into space help? We can still find ways to bump ourselves off out there.
Note, I am very much in favor of space colonization once we get global crime rates down to.. say around a quarter of what Japan has today.
"1700 years ago, three out of every four individuals belonged to a different haplotype. In modern Europe, the number is only one in three. "
This is not a problem - because we have a much larger population today, there is probably an increase in
1) the number of people with a particular haplotype.. even the rare ones (ok, there are obviously exceptions but true in general) 2) the number of haplotypes (new ones emerging)
You know a lot of people in the world live as though airplanes, cars, televisions, and the light bulb were not even invented yet. So even if someday someone invents cool stuff, there will always be a segment of the world to which those things may as well have never been invented. The computer I am typing this to you on is science fiction to them.
So, can we use our existing technology to provide decent preventative health, transportation, and clean water for everyone? It requires no inventing. No new technology. Their governments just need to allow entrepreneurs build a bunch of solar or nuclear power plants to desalinate the water and power heavy construction equipment (currently most third world governments don't allow entrepreneurs to compete against eh state owned corrupt utility companies).
Hey dude that's actually a good idea..all phones should have that.. if the phone/service carried out your instructions/commands or search query only if prepended by a trigger word instead of butting in when unnecessary that is. The trigger word should be pretty unlikely to say in a conversation and/or something user configurable. To find the pizza or whatever you would have to say "Google Searcher, where can I find a restaurant (where I am)?" Since you didnt specify a location, like you said it'll figure out where you are by using the built in GPS or triangulation and the come back with "There is a Domino's 2 miles from you, should I dial it or place it in a file and/or display the number amnd map, company logo etc. in your phone?" (assuming u didnt preconfigure it to do a default o something). Then you can answer it or ask for more places. That's a cool feature to have.
It would be like 411 and a personal assistant rolled into one. I would hope all that the actual voice/conversation analysis stuff happens locally on the phone instead of on a server.. cause otherwise it would be plain creepy.
I wonder if they will come out with an HDTV that has the PS3, DVR, internet browsing, or shopping (or games and movies) functionality built in to it.
I bet the remote for it will suck ass. Won't they build a simpler remote with one or two OLED buttons and/or a touch dial ipod style like the appletv has -- especially if the menus appear on screen? Ideally it would also feature a "touch a button and speak" voice activated remote control capability.
How long before you'll be able to search through pictures or video and the computer does image pattern recognition. So you can type the word "beach" or "jogging" and it will show you all the pictures showing scenery of a beach (or jogging.. or err jogging on the beach). Since camera makers dropped the ball and don't have easy intuitive image tagging capability built into the camera. Ideally a camera would have by now had voice recognition or recording so that you can tag a photo like "me in front of eiffel tower in paris" prior to taking it. Or at the very least a touchscreen system with common options. So now it's up to the AI of the computer to figure out the content of images using mad ocr level image analysis technology. Hmm maybe I should patent something like that.
Fact is.. people are installing Vista on laptops that really shouldn't be running them..
People use their cheap underpowered laptop, get frustrated..curse Dell and Microsoft. And then go to a nicely performing (but more expensive) Mac.
If laptop makers didn't tempt consumers with their underpowered crap, maybe they would have a decent reputation. I don't see how Moore's law is affected.
Apple is the only computer manufacturer whose low end PC's actually perform tolerably.
Just like how there are hundreds of brands of PC's to choose from (this helps keep the price down, improve selection, and companies innovating) we need to have hundreds of brands of cell phones.
We need to be able to home build cell phones. Personally I'd assemble myself a cell phone with a 3.5" (maybe only slightly higher) touchscreen 800 px wide display, 3G, Live Video Share and GPS. I'd run my own distro of Linux or OpenMoko on it.
The HIV virus is a very interesting virus. Of all the common viruses, it is one of most deadly and the hardest to cure. It kills millions of people every year. Which other virus is doing that? Please tell me. This is why it is interesting for study. Most of other infectious diseases people are dying of can be cured with antibiotics, but people never get them.
When the next viral pandemic hits, we want to make sure we know all about how to quickly and effectively deal with it.
Cancer and heart disease do get more funding than AIDS (as they should). Although it's pretty sad that I have to mention this.. you should know that curing AIDS will save many heterosexual and monogamous women's lives in Africa (you and your preacher should be interested in that right?). These are innocent women who's husbands cheated on them with prostitutes. Also importantly, treating AIDS will enable children in Africa to grow up with mothers and/or fathers.
PS> Why don't you stop hating? The venom is eating away your rational thoughts.
I bought the iPhone, but I don't own apple stock. I am happy the iPhone is doing well. I hope it spurs the industry to have a spurt of innovation. It seems that other manufacturers "test the waters" by making a half-ass web feature enabled phone.. obviously it fails with zero sales.. and then they assume nobody wants to web browse on the phone and stop innovating.
Come on, a high res screen for web browsing and touchscreen.. we've been wanting that for a while.. why didn't the other manufacturers come out with a decent one?
I am going to play devil's advocate here..I could be wrong (super likely)..and please understand I'm not dissing.. it just means I am misunderstanding you, or you need more research on it, or suggest different ideas.
Couple of negatives that will have to be worked around/disproven:
1) Physiological response to that enzyme may not be good + will need a reliable turn off/turn on dosage mechanism (prolly not a big deal?) 2) Remaining viruses may have mutant offspring with a different HIV-01 LTR sequence than what the enzyme recognizes.. thus rendering it no longer effective (big issue imho -- hiv's fat rate mutation is why most drugs fail)
"we introduce a gene on this cultured cells that will produce the enzyme"
Why would it be better than doing gene therapy on the patient directly.. or if it's safe simply treat with the enzyme (that way we don't have to worry about having to turn off the production of it or worry about it going haywire)?
Anyway, in future we don't have to use a donor cells.. there's research being done on how you can take stem cells from the patient..modify.. and replant them. But if we have advanced to that point you may as well make them instead produce T-cells that don't even have the receptor that HIV binds to (some people are naturally immune to it because they're lucky enough to lack that receptor) instead of producing this enzyme. I know since the late 80's they have been trying bone marrow transplants and still aren't really proven fully as a successful way of eradicating it --also patients can suffer intense side effects because the donor's cells think they should go on attack mode against the transplantee. Research is continuing though.
Also, we need more work on determining how useful the enzyme is.. here is a quote by Alan Engelman from the section "Perspectives" about the paper in this week's Science magazine:
"First, it will be important to assess the efficiency of Tre function under physiologically relevant conditions in vitro. Because the cell line used by Sarkar et al. likely harbored a few (perhaps only one) unique proviruses, the ability of Tre to eradicate HIV-1 from the multitude of chromosomal locations normally used during integration must be established. It will also be important to analyze substrates that extend beyond the specific loxLTR sequence from which Tre evolved. This region of the LTR is notably well conserved across viral clades, yet some sequences are less than 30% identical to loxP. Although SLiPE could be used to construct additional sequence-specific enzymes, the technology will be impractical if, for example, multiple enzymes are required per patient (HIV-1 diversifies to a quasispecies as patients progress toward AIDS). By far the largest obstacle to potential Tre use in humans will be its safe and effective introduction into salient cell types."
Read the actual paper in Science magazine if you can.
By far, the iphone is the best phone for web browsing. I hope iPhone 2 has even higher resolution (meanwhile the "one step behinders" (motorola, blackberry, sony ericsson, nokia etc) decide that the original iphone resolution must be optimal. It's clear that other phone vendors believe that web developers should make applications that work on QVGA resolution. iPhone's philosophy is different, they will make the device capable of having a decent experience browsing regular websites..they bend to the consumer not the other way around.
It's a design philosophy that no other company has. Well outside of maybe Nintendo.
Now on the negative side of the iPhone the fact that the keyboard takes up a portion of the screen probably isn't the best for IM chatting or email, but the decent resolution makes up for it.
Now as the iPhone takes the market by storm.. other phone vendors will wrongly claim it's the itunes tie in that is making the phone successful.
What you just admitted is that capitalism creates jobs and makes people more wealthy. So wealthy in fact that companies have to move to find cheaper labor. Eventually that means everyone will be rich and able to demand a high wage. Richer people demand more services since they're kids will be better educated they can invest and contribute to a vibrant economy (increased demand and supply capability of cars, housing construction, health care, recreation crap, transportation infrastucture, energy, and mining etc.)
Actually it allows you to do things to the organism which are impossible with its original genome. Since you can put genes into the organism where were never present in that species of organism before.
So what? It can happen naturally as well, and has happened.
Whenever a cell divides, there is the chance of mutation.. this is a probability that DNA in the cell would be arbitrarily modified.
FACT: Maize is widely believed to be a domesticated plant that was artificially selectively bred thousands of years ago in Mesoamerica by the natives. It also contains genes from other species, this is called cross species hybridization and happens in nature. In fact even the human genome contains DNA from multiple viruses that apparently infected and integrated (non harmful/useless?) DNA into us. Also look up how bacteria can transfer drug resistance genes across species via bacteriophages. Here's a link on that http://www.bmj.com/cgi/content/full/317/7159/657.. but google around
FACT: Selective/artificial breeding allows you to bring about features in a plant that are extremely unlikely to have existed in nature.
Example, let's say you want a combination features brought about by the presence of genes A B C D E F G H I J (that's 10) to exist simultaneously in a wheat plant, but the probability of a mutation occurring to bring about any one of those (A or B or C etc.) is 1 in 1000 offspring. That means just to get a plant with feature "A" you have to plant 1000 crops. Big deal? Ok, well to get a plant that has BOTH features A and B you have to plant 1000 x 1000 = 1,000,000 plants. Oh, so you want A B C D E F G H I J...? Guess what? That means you need to have 10^30 plants! That's more plants than would have been in existence if you grew acres of that plant only for billions of generations (years?)!
However with selective breeding.. you can just plant 1000 crops.. select out a gene A. Then ONLY plant the seeds of the plant containing gene/feature A, so then.. your next generation will mostly have gene A, and 1 out of 1000 will have gene B in addition to gene A. Then you select out the plant with both gene A and B, and plant 1000 of those. After just ten years, you will have a plant that has genes A B C D E F G H I J simultaneously.. a plant that has a 1 in 1,000,000,000,000,000,000,000,000,000,000,000,000 chance of existing in nature.
This is also the theory behind why combinations of drugs have a greater chance of curing a disease than giving one drug at a time (it prevents resistance co-evolving).
Anyway whatever this crap is well known.. greenpeace just wants money and power.. they're uninterested in the truth.
Since ur a dev, i figure u may know..With the addition of sculpt mode, is there a feature of hooking up two tablets or an extra touchpad for my left hand? Basically this would allow me to (maybe with the hep of gesturing?) move, rotate, and zoom the object being sculpted in a better fine grained manner 720 degrees + xyz translation while sculpting it. I suppose this can be accomplished using one tablet if it has multitouch?
Hm, I suppose I should download it and check it out.
That's odd, all the studies and anecdotal evidence presented to me suggest otherwise. I don't think the universities themselves are better, you're just more likely to make better contacts here than abroad. And the only reason for that is because Americans have money and a lot of them use it to invest (as Paul pointed out).
Differing from your opinion, I agree with the entire article 100% (including the assertion that our universities are better), BUT.. I do not like the way the article was written. I wish he had used more statistics and numerics than just, for example "half the people in silicon valley have accents". How about showing us the stats of how productive they are etc. The numbers can't be that hard to find. Just because you have references at the end of an article doesnt really boost the usefulness much. Reason i am saying this is that without facts and numerics people who sort of disagree haven't really anything tanglible to be convinced by. And those who already agree, well they don't have reinforcing data they can use in convincing others.
That said it's a good article in that it puts things to forefront that maybe people (especially those in other countries) will research or utilize.
Slashdot Mirror
If it's illegal to unlock the phone, that means I dont own it. Am I leasing it? How the hell else is it possible for me to outright purcahse something and not be able to do whetever the hell i want with it (besides to commit something that is already a crime obviously -like throwing it at someone).
If I buy a t-shirt can they make it illegal for me to use it as a rag?
Is it illegal to color the iphone with a marker? Is it illegal to open up the iphone and melt it down? Is it illegal to take the battery out of the iphone and use the large battery in a hobby RC car project? If it is, it damn well shouldn't be.
Wal-mart isn't forcing people to work at Chinese factories. People are choosing to work there instead of dying of starvation and preventable diseases on the farm.
.. the person wouldn't have a job at all. Walmart is not causing them to be poor. They would be poorer without Walmart. I mean, shit in that case i am being coerced to work too .. as is Bill Gates and Donald Trump. To make a coercion accusation, you have to show that Wal-mart created the horrible farming conditions. Good luck, because those conditions have existed for a long time (people in China as recently as 1950 had a life expectancy of under 40 years .. and infant mortality was very high).
.. by your logic, do I have to pay them my whole salary for life? After all, the value of the doctors work is my whole life. Obviously, if the doctor demanded that .. I would have chosen a different cheaper doctor.
So it's work for walmart or die. I don't see how that's a choice. In fact, I'd call it coercion.
How is it coercion? They aren't the ones causing people to die. Think about it, without the factory
If someone is willing to do work for you for less, why isn't it moral to choose that person?
Because in this case, you'd be exploiting them by paying them wages less than the value of what they produce
Unless a person is being forced to work at gunpoint, that is impossible. Value of work is determined by supply and demand -- not anything intrinsic to the product. If there are others who are willing to provide a product for cheaper, I have the moral prerogative to choose the cheaper one provided by someone who is willing to work harder. The whole point of any work/pay contract is that the each person is choosing to work because they are going to be compensated equal to or more than what they feel the usefulness of their time/energy is. You can always choose not to work if you feel the deal is bad. So a doctor gives me a simple antibiotic and cures me of pneumonia so I live and can work
If someone is willing to do work for you for less, why isn't it moral to choose that person?
... americans who could have been designing technology instead?
.. products and services the world wants .. that Americans can provide.
.. there is already signs of labor shortage emerging in China ..factories are having to provide beter and better incentives for their works (google china labor shortage ) .. just to make products for export.
The alternative to Wal-mart is people starving and dying like in Africa where there is hardly any industry.
Wal-mart isn't forcing people to work at Chinese factories. People are choosing to work there instead of dying of starvation and preventable diseases on the farm.
American workers can easily do other stuff instead of repetitive and boring factory jobs. Plus with the flood of cheap goods less work would be needed. Come on gardeners get paid $50 an hour. You think a factory worker would get anything beyond minimum wage? Also, we currently have a 5% unemployment rate here. Which jobs taht people are currently doing would they have to leave to fill up the shoe making factories? Are you prepared to give up cell phones and great computer software so that you can have shoes made by americans
The world still needs cures for major diseases. There aren't cheap cars of BMW quality. Ferrari performance is not available cheaply yet. Not everyone has a large house, there is mad demand fror pre-fabbed structures so that infrastructure to be built. All of this shows there is a need for products and services
Do you think China has enough workers to construct all the machinery to develop their infrastructure? I don't think so
If someone is providing a service or item that people want, you shouldn't stand in the way of their transaction. After all, if you are replaced by robots would you still be indignant? The world is manufacturing crap for the US. The US should make things to exchange. Do you think the world wants to collect pieces of paper?? If they want to earn all this money, they are doing it because they too require services.
.. just like they have the right to refuse the service entirely.
.. this can be in the form of fabricating things in the US and shipping them elsewhere. This is already done for airplanes etc. Most of the world is severely undeveloped and needs infrastructure. As long as people have a need for roads, sewers, and houses ..this need is there.
.. until people have self contained in-home energy generators that manufactures happy pills and food from raw minerals. But at that point there would be no _need_ for jobs.
Instead of being pissed that others are making goods that people want to buy, there are plenty of things America can do to maintain its lead. People get paid for providing a useful service cheaper than others. If a service can be gotten for cheaper elsewhere, then a person should have the right to get it from elsewhere
Anyway, there are still things you can do to earn money:
1) Invent cures for diseases and slow down aging so that the life expectancy can be 120
2) Develop cheaper sources of energy that can be used to purify and distribute water to people who need it
3) Find out how to reduce crime to Japan's level, and then to one quarter of that. Then provide consulting to other countries.
4) Assist in building global infrastructure
There are simply not enough workers in the world to build all everything people need, so there will always be jobs
Multiple sclerosis is when your immune system attacks a nerve's covering called myelin. What the vaccine does is it gets the immune system to stop targetting the myelin by causing a reduction in the T-cells that attack it. If it works as they say, and have demonstrated, it only reduces the number of T-cells that target the myelin protein, not other stuff.
I think it's clear that the biggest threat to our existence as a species is our own selves, if we can't solve that problem how does going off into space help? We can still find ways to bump ourselves off out there.
.. say around a quarter of what Japan has today.
Note, I am very much in favor of space colonization once we get global crime rates down to
Just because they don't have a practical idea doesn't mean they can't rip off investors.
"1700 years ago, three out of every four individuals belonged to a different haplotype. In modern Europe, the number is only one in three. "
.. even the rare ones (ok, there are obviously exceptions but true in general)
This is not a problem - because we have a much larger population today, there is probably an increase in
1) the number of people with a particular haplotype
2) the number of haplotypes (new ones emerging)
You know a lot of people in the world live as though airplanes, cars, televisions, and the light bulb were not even invented yet. So even if someday someone invents cool stuff, there will always be a segment of the world to which those things may as well have never been invented. The computer I am typing this to you on is science fiction to them.
So, can we use our existing technology to provide decent preventative health, transportation, and clean water for everyone? It requires no inventing. No new technology. Their governments just need to allow entrepreneurs build a bunch of solar or nuclear power plants to desalinate the water and power heavy construction equipment (currently most third world governments don't allow entrepreneurs to compete against eh state owned corrupt utility companies).
Hey dude that's actually a good idea ..all phones should have that .. if the phone/service carried out your instructions/commands or search query only if prepended by a trigger word instead of butting in when unnecessary that is. The trigger word should be pretty unlikely to say in a conversation and/or something user configurable. To find the pizza or whatever you would have to say "Google Searcher, where can I find a restaurant (where I am)?" Since you didnt specify a location, like you said it'll figure out where you are by using the built in GPS or triangulation and the come back with "There is a Domino's 2 miles from you, should I dial it or place it in a file and/or display the number amnd map, company logo etc. in your phone?" (assuming u didnt preconfigure it to do a default o something). Then you can answer it or ask for more places. That's a cool feature to have.
.. cause otherwise it would be plain creepy.
It would be like 411 and a personal assistant rolled into one. I would hope all that the actual voice/conversation analysis stuff happens locally on the phone instead of on a server
I wonder if they will come out with an HDTV that has the PS3, DVR, internet browsing, or shopping (or games and movies) functionality built in to it.
I bet the remote for it will suck ass. Won't they build a simpler remote with one or two OLED buttons and/or a touch dial ipod style like the appletv has -- especially if the menus appear on screen? Ideally it would also feature a "touch a button and speak" voice activated remote control capability.
How long before you'll be able to search through pictures or video and the computer does image pattern recognition. So you can type the word "beach" or "jogging" and it will show you all the pictures showing scenery of a beach (or jogging .. or err jogging on the beach). Since camera makers dropped the ball and don't have easy intuitive image tagging capability built into the camera. Ideally a camera would have by now had voice recognition or recording so that you can tag a photo like "me in front of eiffel tower in paris" prior to taking it. Or at the very least a touchscreen system with common options. So now it's up to the AI of the computer to figure out the content of images using mad ocr level image analysis technology. Hmm maybe I should patent something like that.
Fact is.. people are installing Vista on laptops that really shouldn't be running them..
..curse Dell and Microsoft. And then go to a nicely performing (but more expensive) Mac.
People use their cheap underpowered laptop, get frustrated
If laptop makers didn't tempt consumers with their underpowered crap, maybe they would have a decent reputation. I don't see how Moore's law is affected.
Apple is the only computer manufacturer whose low end PC's actually perform tolerably.
Ask the old widow "Silence Dogood" aka Benjamin Franklin.
Google it, you're obviously ignorant of the history.
Anonymity is critical to democracy.
Why put on make up or wear clothes if you have nothing to hide?
Oprah Winfrey. Paris Hilton.
Folks, sometimes privacy is a civil service.
Just like how there are hundreds of brands of PC's to choose from (this helps keep the price down, improve selection, and companies innovating) we need to have hundreds of brands of cell phones.
We need to be able to home build cell phones. Personally I'd assemble myself a cell phone with a 3.5" (maybe only slightly higher) touchscreen 800 px wide display, 3G, Live Video Share and GPS. I'd run my own distro of Linux or OpenMoko on it.
The HIV virus is a very interesting virus. Of all the common viruses, it is one of most deadly and the hardest to cure. It kills millions of people every year. Which other virus is doing that? Please tell me. This is why it is interesting for study. Most of other infectious diseases people are dying of can be cured with antibiotics, but people never get them.
.. you should know that curing AIDS will save many heterosexual and monogamous women's lives in Africa (you and your preacher should be interested in that right?). These are innocent women who's husbands cheated on them with prostitutes. Also importantly, treating AIDS will enable children in Africa to grow up with mothers and/or fathers.
When the next viral pandemic hits, we want to make sure we know all about how to quickly and effectively deal with it.
Cancer and heart disease do get more funding than AIDS (as they should). Although it's pretty sad that I have to mention this
PS> Why don't you stop hating? The venom is eating away your rational thoughts.
I bought the iPhone, but I don't own apple stock. I am happy the iPhone is doing well. I hope it spurs the industry to have a spurt of innovation. .. obviously it fails with zero sales.. and then they assume nobody wants to web browse on the phone and stop innovating.
.. why didn't the other manufacturers come out with a decent one?
It seems that other manufacturers "test the waters" by making a half-ass web feature enabled phone
Come on, a high res screen for web browsing and touchscreen.. we've been wanting that for a while
I am going to play devil's advocate here ..I could be wrong (super likely) ..and please understand I'm not dissing.. it just means I am misunderstanding you, or you need more research on it, or suggest different ideas.
.. thus rendering it no longer effective (big issue imho -- hiv's fat rate mutation is why most drugs fail)
.. or if it's safe simply treat with the enzyme (that way we don't have to worry about having to turn off the production of it or worry about it going haywire)?
.. there's research being done on how you can take stem cells from the patient ..modify .. and replant them. But if we have advanced to that point you may as well make them instead produce T-cells that don't even have the receptor that HIV binds to (some people are naturally immune to it because they're lucky enough to lack that receptor) instead of producing this enzyme. I know since the late 80's they have been trying bone marrow transplants and still aren't really proven fully as a successful way of eradicating it --also patients can suffer intense side effects because the donor's cells think they should go on attack mode against the transplantee. Research is continuing though.
Couple of negatives that will have to be worked around/disproven:
1) Physiological response to that enzyme may not be good + will need a reliable turn off/turn on dosage mechanism (prolly not a big deal?)
2) Remaining viruses may have mutant offspring with a different HIV-01 LTR sequence than what the enzyme recognizes
"we introduce a gene on this cultured cells that will produce the enzyme"
Why would it be better than doing gene therapy on the patient directly
Anyway, in future we don't have to use a donor cells
Also, we need more work on determining how useful the enzyme is.. here is a quote by Alan Engelman from the section "Perspectives" about the paper in this week's Science magazine:
"First, it will be important to assess the efficiency of Tre function under physiologically relevant conditions in vitro. Because the cell line used by Sarkar et al. likely harbored a few (perhaps only one) unique proviruses, the ability of Tre to eradicate HIV-1 from the multitude of chromosomal locations normally used during integration must be established. It will also be important to analyze substrates that extend beyond the specific loxLTR sequence from which Tre evolved. This region of the LTR is notably well conserved across viral clades, yet some sequences are less than 30% identical to loxP. Although SLiPE could be used to construct additional sequence-specific enzymes, the technology will be impractical if, for example, multiple enzymes are required per patient (HIV-1 diversifies to a quasispecies as patients progress toward AIDS). By far the largest obstacle to potential Tre use in humans will be its safe and effective introduction into salient cell types."
Read the actual paper in Science magazine if you can.
Is there some reason this "unbreakable" DRM scheme can't simply be ported to HD DVD players if it's so wonderful?
By far, the iphone is the best phone for web browsing. I hope iPhone 2 has even higher resolution (meanwhile the "one step behinders" (motorola, blackberry, sony ericsson, nokia etc) decide that the original iphone resolution must be optimal. It's clear that other phone vendors believe that web developers should make applications that work on QVGA resolution. iPhone's philosophy is different, they will make the device capable of having a decent experience browsing regular websites ..they bend to the consumer not the other way around.
.. other phone vendors will wrongly claim it's the itunes tie in that is making the phone successful.
It's a design philosophy that no other company has. Well outside of maybe Nintendo.
Now on the negative side of the iPhone the fact that the keyboard takes up a portion of the screen probably isn't the best for IM chatting or email, but the decent resolution makes up for it.
Now as the iPhone takes the market by storm
What you just admitted is that capitalism creates jobs and makes people more wealthy. So wealthy in fact that companies have to move to find cheaper labor. Eventually that means everyone will be rich and able to demand a high wage. Richer people demand more services since they're kids will be better educated they can invest and contribute to a vibrant economy (increased demand and supply capability of cars, housing construction, health care, recreation crap, transportation infrastucture, energy, and mining etc.)
Actually it allows you to do things to the organism which are impossible with its original genome. Since you can put genes into the organism where were never present in that species of organism before.
.. this is a probability that DNA in the cell would be arbitrarily modified.
.. but google around
.. you can just plant 1000 crops .. select out a gene A. Then ONLY plant the seeds of the plant containing gene/feature A, so then .. your next generation will mostly have gene A, and 1 out of 1000 will have gene B in addition to gene A. Then you select out the plant with both gene A and B, and plant 1000 of those. After just ten years, you will have a plant that has genes A B C D E F G H I J simultaneously .. a plant that has a 1 in 1,000,000,000,000,000,000,000,000,000,000,000,000 chance of existing in nature.
.. greenpeace just wants money and power .. they're uninterested in the truth.
So what? It can happen naturally as well, and has happened.
Whenever a cell divides, there is the chance of mutation
FACT: Maize is widely believed to be a domesticated plant that was artificially selectively bred thousands of years ago in Mesoamerica by the natives. It also contains genes from other species, this is called cross species hybridization and happens in nature. In fact even the human genome contains DNA from multiple viruses that apparently infected and integrated (non harmful/useless?) DNA into us. Also look up how bacteria can transfer drug resistance genes across species via bacteriophages. Here's a link on that http://www.bmj.com/cgi/content/full/317/7159/657
FACT: Selective/artificial breeding allows you to bring about features in a plant that are extremely unlikely to have existed in nature.
Example, let's say you want a combination features brought about by the presence of genes A B C D E F G H I J (that's 10) to exist simultaneously in a wheat plant, but the probability of a mutation occurring to bring about any one of those (A or B or C etc.) is 1 in 1000 offspring. That means just to get a plant with feature "A" you have to plant 1000 crops. Big deal? Ok, well to get a plant that has BOTH features A and B you have to plant 1000 x 1000 = 1,000,000 plants. Oh, so you want A B C D E F G H I J...? Guess what? That means you need to have 10^30 plants! That's more plants than would have been in existence if you grew acres of that plant only for billions of generations (years?)!
However with selective breeding
This is also the theory behind why combinations of drugs have a greater chance of curing a disease than giving one drug at a time (it prevents resistance co-evolving).
Anyway whatever this crap is well known
Since ur a dev, i figure u may know ..With the addition of sculpt mode, is there a feature of hooking up two tablets or an extra touchpad for my left hand? Basically this would allow me to (maybe with the hep of gesturing?) move, rotate, and zoom the object being sculpted in a better fine grained manner 720 degrees + xyz translation while sculpting it. I suppose this can be accomplished using one tablet if it has multitouch?
Hm, I suppose I should download it and check it out.
That's odd, all the studies and anecdotal evidence presented to me suggest otherwise. I don't think the universities themselves are better, you're just more likely to make better contacts here than abroad. And the only reason for that is because Americans have money and a lot of them use it to invest (as Paul pointed out).
.. I do not like the way the article was written. I wish he had used more statistics and numerics than just, for example "half the people in silicon valley have accents". How about showing us the stats of how productive they are etc. The numbers can't be that hard to find. Just because you have references at the end of an article doesnt really boost the usefulness much. Reason i am saying this is that without facts and numerics people who sort of disagree haven't really anything tanglible to be convinced by. And those who already agree, well they don't have reinforcing data they can use in convincing others.
Differing from your opinion, I agree with the entire article 100% (including the assertion that our universities are better), BUT
That said it's a good article in that it puts things to forefront that maybe people (especially those in other countries) will research or utilize.