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MIT Team Creates Cancer Stem Cells

MIT scientists and colleagues have found a way in the lab to create large amounts of cancer stem cells, the cells that can initiate tumors. The work, reported in the August 13 issue of Cancer Cell, could be a boon to researchers who study these elusive cells. Labs could easily grow them for use in experiments.

91 of 124 comments (clear)

  1. Almost there! by GrapeSteinbeck · · Score: 5, Funny

    Now we just need to to infect the top seven world leaders with it and we'll have a cure. (MAD TV reference)

    1. Re:Almost there! by Atriqus · · Score: 1

      Why was that modded troll? It was a joke; he even said what he was referencing.

      --
      Hey, look! It's Bono's brother.
    2. Re:Almost there! by Chris+Burke · · Score: 1

      Since it sucked less than SNL.

      Though lately it's been suffering from the same thing that made SNL unwatchable for years: "the joke the skit is based around is funny for thirty seconds but the skit is seven minutes long" syndrome.

      --

      The enemies of Democracy are
    3. Re:Almost there! by Chris+Burke · · Score: 1

      Well maybe I didn't notice because compared to SNL their skits were short and punchy.

      --

      The enemies of Democracy are
    4. Re:Almost there! by kelzer · · Score: 2, Funny

      Now we just need to to infect the top seven world leaders with it and we'll have a cure. (MAD TV reference)

      Or just infect the top one world leader. Then we all win whether they find a cure or not. (Just kidding. I don't even want him to suffer like that. Now hemorrhoids, yeah, a real nasty case of hemorrhoids would be good!)

      --

      ---------------------------------------------
      SERENITY NOW!!!!!!!!!!!!!!!!
    5. Re:Almost there! by Bluesman · · Score: 1

      "the joke the skit is based around is funny for thirty seconds but the skit is seven minutes long"

      Funny for thirty seconds? Sounds like a good episode of SNL.

      --
      If moderation could change anything, it would be illegal.
    6. Re:Almost there! by HeroreV · · Score: 1

      the joke the skit is based around is funny for thirty seconds but the skit is seven minutes long That's why I love Weekend Update! They still have stupid guests that do that, but most jokes only last a few seconds. Overall, Weekend Update is the best part of SNL and MadTV.
    7. Re:Almost there! by jollyreaper · · Score: 1

      >> Now we just need to to infect the top seven world leaders with it and we'll have a cure. (MAD TV
      >>reference)

      >Or just infect the top one world leader. Then we all win whether they find a cure or not. (Just
      >kidding. I don't even want him to suffer like that.

      You are a good-hearted person. I'm not. I wish kidney stone cancer upon him with a nasty case of goatse-butt.

      --
      Kwisatz Haderach
      Sell the spice to CHOAM
      This Mahdi took Shaddam's Throne
  2. Tag: Bioweapon? by b0s0z0ku · · Score: 1
    (unlikely though due to the fact that they'd have to be tailored specifically for each victim, otherwise the immune system would destroy them).

    Might work as a covert assassination weapon if they can get hold of the mark's DNA and create cell lines.

    -b.

    1. Re:Tag: Bioweapon? by Otter · · Score: 4, Informative

      There are already plenty of very effective ways to cause cancer that are a lot easier, cheaper and more easily deliverable.

    2. Re:Tag: Bioweapon? by pajeromanco · · Score: 4, Funny

      There are already plenty of very effective ways to cause cancer that are a lot easier, cheaper and more easily deliverable. Cigarettes?
      --
      Now I am sad.
    3. Re:Tag: Bioweapon? by smookumy · · Score: 1

      It's not a weapon, it's a cure for /life/.

    4. Re:Tag: Bioweapon? by cayenne8 · · Score: 1
      " There are already plenty of very effective ways to cause cancer that are a lot easier, cheaper and more easily deliverable.

      Cigarettes?"

      Well, those are more "self-inflicted"....but, they are fun.

      :-)

      --
      Light travels faster than sound. This is why some people appear bright until you hear them speak.........
    5. Re:Tag: Bioweapon? by b0s0z0ku · · Score: 1
      There are already plenty of very effective ways to cause cancer that are a lot easier, cheaper and more easily deliverable.

      ... but not 100% reliable or even close to it. Some people just _don't react_ to carcinogens. Or the other hand, introducing tumour tissue that's tailored to their immunities...

      -b.

    6. Re:Tag: Bioweapon? by Otter · · Score: 2, Funny

      I'm talking about laboratory agents, not Tab or pastrami.

    7. Re:Tag: Bioweapon? by veganboyjosh · · Score: 1

      I thought Tab only caused cancer in lab animals in California... And don't even get me started on the pastrami.

    8. Re:Tag: Bioweapon? by EMH_Mark3 · · Score: 1

      He said 'cheaper'...

      --
      Burn the land and boil the sea, you can't take the sky from me
    9. Re:Tag: Bioweapon? by e2d2 · · Score: 2

      Yes Mr President, our assassin has delivered the payload. The target should be dead in .. 5-10 years depending on health care and current insurance plan.

    10. Re:Tag: Bioweapon? by dmclap · · Score: 2, Interesting

      Assassination weapon? Cancer tends to take years to kill you. Sure, while this might speed the process up to several months or something, that still gives the person in question plenty of time to spill everything that they know, or otherwise cause serious damage to the cause that the assassins are trying to protect.

      No, there are much better and more clever ways to do these things. Like how they iced Georgi Markov (always a classic).

    11. Re:Tag: Bioweapon? by ScotlynHatt · · Score: 1

      Actually, this is dependent on the delivery system. For instance, one could use . . . say . . . bullets dipped in the stuff made from the generic DNA.

    12. Re:Tag: Bioweapon? by Thusi02 · · Score: 1

      This is precisely what I was thinking at an initial read. However, I am not too sure that there are "100% certain" effective ways to cause cancer to produce. This method of creating cancer cells is much more efficient and in a controlled manor. Having this enormous power of creating cancer can be deadly for the weak minds as they will use it for evil than good. There is definitely a "good" that can come out of it as when there are abundant amount of resources to be tested with, the researchers will try every possible combination of alterations which will eventually find a way to suppress the cancer cells. Thus curing cancer forever (as optimistic as that sounds).

      Cheers,
      Thusjanthan Kubendranathan.

      --
      For all your coding questions? http://letstalkcoding.com
      For all your development needs! http://simtik.com
  3. I hope we have ethical researchers by PresidentEnder · · Score: 1

    The work, reported in the August 13 issue of Cancer Cell, could be a boon to researchers who study these elusive cells. Labs could easily grow them for use in experiments. Or, you know, give everyone they don't like cancer. Just saying.
    --
    I used to carry a bottle of whiskey for snake bite. And two snakes. -Nefarious Wheel
    1. Re:I hope we have ethical researchers by XxtraLarGe · · Score: 1

      Or, you know, give everyone they don't like cancer. Just saying. Terrance: Hey Scott, guess what?
      [Fart]
      [Laughter]
      Scott: Uh, I hate you more than ever Terrance and Phillip. I absolutely abhor you both!
      Scott is motioning peculiarly at Terrance and Phillip.
      Phillip: What are you doing Scott?
      Scott: I'm wishing cancer upon you.
      Terrance: Cancer!?
      Scott: That's right, I'm trying to give you cancer with my mind.
      Terrance: Ah, stop that!
      Terrance hides behind Phillip.
      Phillip: Hey--Don't give ME cancer!
      --
      Taking guns away from the 99% gives the 1% 100% of the power.
  4. Oh my by accessdeniednsp · · Score: 1

    "No good will come of this".

    I got images of various "Resident Evil" scenes with zombies flooding the Northeast US and ... oh my.

    On a serious note, kudos to the lab geeks at MIT! You guys do some fantastic work :)

    1. Re:Oh my by jd · · Score: 2, Funny

      Odd. I got the image of a factory putting the tumors into jelly molds and producing politicians, lawyers and civil servants.

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  5. Re:New biological weapon? by 2.7182 · · Score: 4, Insightful

    It's just you. Just because they made some small technical advance and then ran to the media with it doesn't mean anything. Before this comes out, just wait for the super efficient solar cells, face recognition, robot servants, super nanotube application (fill in here), gene therapy that doens't kill helpless teenagers, fusion on the desktop, and god knows how many other vaportechnologies.

  6. Don't give me cancer! by EvilRyry · · Score: 3, Funny

    Terrance: What are you doing?
    Scott: I am wishing cancer upon you.
    Phillip: What?
    Scott: I am giving you cancer with my mind.
    Phillip: No, don't give me cancer!

  7. They gave the stem cells a pack of Marlboros by postbigbang · · Score: 2, Funny

    and look what happened....

    --
    ---- Teach Peace. It's Cheaper Than War.
    1. Re:They gave the stem cells a pack of Marlboros by cadu · · Score: 1

      the pack smashed the stem cell sample. 48 hours later they remove the pack and voilá, smashed [not cancer-growing] stem cells!

      now, if you had told me they grew a mouth and a pair of lungs from the stem cells and gave those a pack of marlboros, i would actually have believed it. :P

  8. Scientists are the real moral crusaders by HumanSockPuppet · · Score: 5, Interesting

    This actually brings up an interesting idea.

    I've always been a proponent of the idea that scientists were the true moral crusaders of our age, not protesters, demonstrators, and certainly not religious zealots.

    Think of it this way - when scientists have perfected a means for reproducing reliable and testable human cancer cells in a laboratory, there will no longer be any need to use lab rats in cancer research. Cancer will be closer to being cured, and rats will be spared. What has the Animal Liberation Front done on that magnitude, apart from burn medical research facilities?

    I imagine that when we are able to create vehicles that produce no pollution, it will be considered excessive and morally repugnant to drive gas guzzlers. I imagine that we have developed a means of engineering meat that it will be considered immoral to kill living animals to get it. The idea here is that immorality is scaled and determined in terms of gross excess of what is necessary for survival, and that our technology makes survival easier (thus altering the scale).

    --
    Inserting [insert witty signature here] here does not constitute a witty signature.
    1. Re:Scientists are the real moral crusaders by Pojut · · Score: 1

      why are we still using rats when there are people sitting on death row?


      For the same reasons that those people get their arm swabbed with alcohol before a lethal injection...because we as a race have turned into a bunch of pussies.

      I say we restore the Roman Colosseum and throw 'em to the lions.
    2. Re:Scientists are the real moral crusaders by Aladrin · · Score: 2, Interesting

      While I disagree with your statement that "scientists were the true moral crusaders of our age", I find the notion that 'morality depends on science' to be intriguing.

      But if that's so, why is it okay to eat meat right now? You can adequately survive on plants and medical supplements right now. Does this not mean that killing animals is wrong already, or does personal comfort/quality of life mean alter morality also?

      Personally, I don't find it immoral at all to eat animals, no matter the situation. I will admit that if I was the one that had to kill them, there'd probably be less meat on my plate each night, though.

      --
      "If you make people think they're thinking, they'll love you; But if you really make them think, they'll hate you." - DM
    3. Re:Scientists are the real moral crusaders by AndyG314 · · Score: 1

      1) Because the number of death row inmates is not nearly sufficent.
      2) Because death row inmates are large, violent, difficult to controll and eat a lot, while mice are small, dorcile, easy to controll and don't eat much at all.

      --
      If it's dead, you killed it.
    4. Re:Scientists are the real moral crusaders by HumanSockPuppet · · Score: 1

      Keep in mind that while morality cannot be quantified, much of its definition is drawn from human need. Most of the omnivorous among us (myself included) would agree that there is a quality to the experience of eating meat which is just as essential as the nutrients which the meat provides. Supplements also tend to be more costly than meat, and the very nature of their structure at the molecular level makes them sub-optimal for digestion in comparison with animal meat.

      You raise good points, but I don't think they are significant enough to affect the scale just yet. When we are able to recreate a steak with the push of a button, then we can expect attitudes to change.

      --
      Inserting [insert witty signature here] here does not constitute a witty signature.
    5. Re:Scientists are the real moral crusaders by vertinox · · Score: 1, Insightful

      I say we restore the Roman Colosseum and throw 'em to the lions.

      Fine with me as long as we keep up the practice of throwing the Christians in before noon?

      Oh maybe, you mean there was a reason they outlawed slavery and gladiator fights other than law and order?

      --
      "I am the king of the Romans, and am superior to rules of grammar!"
      -Sigismund, Holy Roman Emperor (1368-1437)
    6. Re:Scientists are the real moral crusaders by Ginger+Unicorn · · Score: 1

      you're not answering the question

      --
      (1.21 gigawatts) / (88 miles per hour) = 30 757 874 newtons
    7. Re:Scientists are the real moral crusaders by Pojut · · Score: 1

      Fine with me as long as we keep up the practice of throwing the Christians in before noon?
      I have a BETTER idea...how about we throw the folks on death row to the CHRISTIANS?

      And then we gut out the christians and make giant bongs out of them. Good times will be had by all (except for the christians, of course...)
    8. Re:Scientists are the real moral crusaders by Himring · · Score: 1

      Cancer will be closer to being cured, and rats will be spared.

      Which reminds me of that joke:

      "Scientists have started using lawyers in experiments instead of rats for two reasons: number one, the scientists don't get as attached to the lawyers and two, there are some things not even a rat will do...."

      --
      "All great things are simple & expressed in a single word: freedom, justice, honor, duty, mercy, hope." --Churchill
    9. Re:Scientists are the real moral crusaders by CopaceticOpus · · Score: 1

      1) If you are crusading for a cause that is good and moral, it is something to be proud of.

      2) None of these details about medical science have much effect on the parent's main points.

      3) Just because science can't solve every problem doesn't mean it can't do good. Scientists who worked to defeat polio were doing a good and moral thing. The world is a better place, and many children's lives were saved, because of that work. The fact that the world still contains evil, and that some of the children who were saved grew up to be criminals, doesn't take away from the goodness of what was accomplished.

    10. Re:Scientists are the real moral crusaders by CopaceticOpus · · Score: 1

      Yes, for that benchmark we have to look to PETA.

      ;)

    11. Re:Scientists are the real moral crusaders by sonpal · · Score: 1

      Your idea is pretty interesting, but it needs to be developed further. The two examples that you cited are moral improvements that occurred as a result of scientists to work to improve something. What also needs to be considered is why the scientists were working on those tasks. Assuming that the research was not being done in academia, in both instances the motivation would be economics - the first one is convenience -> productivity -> faster research -> lower costs, and the second one is low pollution -> tax incentives for car companies or revenues for alternative energy companies -> profits. While improvements over current paradigms can in certain instances address moral issues, we must also remember that using rats in the first place, or designing gas guzzlers would not be possible without scientists / engineers. Perhaps there were moral isues that we solved in the past that created what we consider moral problems today - e.g. you could argue that using rats is more moral than using prisoners on death row, or that using cars was more moral than using horses, but I would argue that it's economics and convenience (which is also economics). Cars are cheaper than horses and require less maintenance, and rats are easier to obtain than prisoners (also economics in a twisted way). I think we end up in the same place that all technology related moral arguments end up - technology itself is amoral, but can certainly be directed at solving or creating moral problems. I do agree that scientists / engineers are the ones building the technology that solves or creates these problems, but generally the motivation for this is economic unless it is done in a non-profit environment such as academia. Now if we could align ethics and economics, everyone could be a moral crusader. Although at that point, either ethics or ecnomics would redudant, and therefore one of them would have to be obsolete (no economics in Star Trek). -- Hiten

    12. Re:Scientists are the real moral crusaders by Attila+Dimedici · · Score: 1

      Most human cell lines that are used in the laboratory are already cancer cells. The normal human cell reproduces a set number of times and then dies out. Cancer cells don't do this (that is part of why they cause a problem in the body). In many cases when scientists wanted to study a particular type of cell outside of the body, they would find a likely candidate and attempt to induce it to become cancerous so that they could grow it indefinitely in the lab. With rare exceptions, it is impossible to maintain a normal human cell line for more than a couple of years.

      --
      The truth is that all men having power ought to be mistrusted. James Madison
    13. Re:Scientists are the real moral crusaders by sakonofie · · Score: 1
      A) Scientists prefer to think of morality from utilitarian perspective as the future utility of their results MIGHT overweight what they did to get there. Now we all know that the ends don't justify the means expect when they do. This is about the point at which everyone throws up their hands and makes a personal decision about a morality question they can not answer. B)

      vehicles that produce no pollution . I am not sure exactly what you mean by this but I am fairly sure it is ridiculous any which way it is taken. The proper answer probably comes from the set {It is called a bicycle/horse and no one gives a shit, See laws of thermodynamics}.
    14. Re:Scientists are the real moral crusaders by xilmaril · · Score: 1

      Even in private industry, the sole motivator of research is not profit. Researchers will tend to work for whoever will pay them well, but given that there is a limited supply of genius, smart people tend to choose their field of research based on their own personal feelings, including their morals.

      While morals don't really explain the massive research behind Viagra, they do explain some of the morals behind urinary tract infection research, for example, since there really are more profitable fields of medical research to be in.

    15. Re:Scientists are the real moral crusaders by atchon · · Score: 1

      The thing about testing against just cells is that that you miss out on interactions that one may not anticipate. As a researcher we have drugs which have worked fantastically in the test tube, but don't do anything in a mouse because of the complexity of the overall system. Rats are necessary because it gives a good model of overall what will happen if the mouse is given a drug because it offers the full system not just cells in a tube. As to later comments about using death row inmates, they live too long. The idea of a mouse model is you can observe there entire life within a couple years, think most research mice live 3 years. Which is better than having to observe a actual human over its entire life of 60-70 years on average. I do agree that us scientists seem generally more aware of the problems facing humanity and many do make efforts towards this.

  9. Re:New biological weapon? by DDLKermit007 · · Score: 3, Informative

    Has to be tailored to each person. At that it's highly questionable. Otherwise the body will just destroy the cells. Cancer lives by playing the game of cups, and balls with the immune system. When it finds the right way to act like it's part of the body to the immune system it's kind of a bitch to kill off. Easier to just poison someone. Plus this would require a fairly advanced lab. It takes far less, and generates allot more fear mailing an envelope with Anthrax in it to one person.

  10. Re:Isn't this going in reverse? by Jorgandar · · Score: 1

    call me crazy, but usually you have to have a ready supply of the thing you're trying to cure in order to study it, in order to cure it. where is the ready supply of cancer? oh yes, growing in people. This seems like a better option.

  11. Hey we're science! by Floritard · · Score: 1

    "Hey we made cancer airborne and contagious! You're welcome! We're Science. We're all about coulda not shoulda."
    - Patton Oswalt - Werewolves & Lollipops

  12. Re:New biological weapon? by Monoliath · · Score: 1

    You beat me to asking the very same question, I look forward to the replies that will follow.

    This all seems really really...creepy

    And before someone goes off about how every modern advancement of science has been called creepy by some activist group or individual...you have to admit...this takes it to a whole new level.

  13. Re:New biological weapon? by BlueParrot · · Score: 3, Interesting

    fusion on the desktop
    The Oil industry has used desktop-sized fusion devices for prospecting for decades. They are also commonly used as neutron sources for various scientific experiments. Heck, there are even teenagers building their own fusors in the basement. Now if you were talking about fusion devices capable of yielding a net power output at prices competitive with existing energy sources, then that is quite a different thing, but I don't think anybody has ever claimed to have achieved this, not even the cold-fusion crowd...
  14. Re:New biological weapon? by milamber3 · · Score: 2, Informative

    Not really, you would need the cells to be immunologically compatible to each person you wanted to infect. That would be harder than a large number of other ways to hurt them. On the other hand, a biological weapon could come from the method they use to turn the cells into cancer stem cells. This generally involves a gene transfer using a virus vector. That kind of virus could be used to create these types of cells inside someone. I don't think large scale virus vector weapons are currently feasible but it may be something to worry about in the future.

  15. Re:Big ol' mug... by Debello · · Score: 3, Funny

    "Hello, Husband. How was work? I made you a cup of your FAVORITE COFFEE. It's fresh... Now drink up. Drink it ALL... Feel anything? No? You will in a few years."

  16. Great, guys. Thanks. by jwriney · · Score: 1

    Hooray! Try new Instant Cancer! 50% faster than regular cancer. Available at your grocer's dairy case.

  17. Re:Isn't this going in reverse? by Lord+Bitman · · Score: 1

    Wasn't that the plot of Mission Impossible 2?

    --
    -- 'The' Lord and Master Bitman On High, Master Of All
  18. Re:Isn't this going in reverse? by geoffrobinson · · Score: 1

    It's hard to remember the plot details. But I remember a lot of slow motion.

    --
    Except for ending slavery, the Nazis, communism, & securing American independence, war has never solved anything.
  19. Great! Now this won't happen by DrScotsman · · Score: 2, Funny

    Russell Crowe: Well, we couldn't find cancer, but we found a man with cancer. *Punches old man* Take that, cancer! And that! *Punches again*

  20. Re:New biological weapon? by andy666 · · Score: 1

    And you forgot to mention robot vacuum cleaners (that don't get stuck everywhere - personal experience), penis enlargers (I've still got my hopes up), bacteria that eat toxic waste and poop gold, Hurd, new storage method X that promises petabyte drives (our company expects them to be on the market in less than a year), nanorobot swarms, and the new Apple iCar (ooops I shouldn't have mentioned that I am an Apple employee. Wouldn't want to create a lot of rumors and speculation.)

  21. We've found the cure! by MajorG17 · · Score: 4, Funny

    Eureka! All we have to do to cure cancer is take this machine and reverse the polarity!!!

  22. Re:Great! Now this won't happen by Zekasu · · Score: 1

    I'm not sure why, but I found this funny enough to laugh at. --- Cancer cells, buy them today. They're ammonia and fat-free now.

  23. Re:Big ol' mug... by Uzuri · · Score: 1

    Heh.

    Well, you know, all these cures for cancer in mice made a market for an uncure. We all should have seen this coming.

    --
    I'm a she-slashdotter... but I make up for it by living with my folks.
  24. Re:New biological weapon? by 2.7182 · · Score: 1

    I think she meant fusion on the desktop that would be a viable powersource.

  25. God damn' scientists!!! by tsbiscaro · · Score: 1

    What's the point of that??? Ok, now I have to leave my office... Time for a cigarrete!!

  26. Kind of ironic.... by slapout · · Score: 1

    ...that bringing more cancer cells into the world makes people happy.

    --
    Coder's Stone: The programming language quick ref for iPad
    1. Re:Kind of ironic.... by ChrisMounce · · Score: 1

      "I have to laugh, because I've outsmarted even myself. My enemy, my foe, is a cancer. In order to conquer the cancer, I have to learn to think like an cancer. And, whenever possible, to look like one. I've gotta get inside this guy's cell wall and crawl around for a few days."

  27. Re:New biological weapon? by Bastard+of+Subhumani · · Score: 2, Funny

    Then it's nothing to worry about. There's no possible way anybody could get a sample of a slashdotter's DNA.

    --
    Only three things are certain; death, taxes, and apocryphal quotations - Ben Franklin.
  28. Re:New biological weapon? by o-hayo · · Score: 1
    Oh no! Not terrorists!

    Seriously, half the items under your kitchen sink can probably be used by terrorists. In fact does your home have natural gas running to it? Seal that house up, start a leak, light a long fuse... I think I've found out that you own a Weapon of Mass Neighborhood Destruction!!!! How do you sleep at night?

  29. Anyone running a pool ... by benedict · · Score: 1

    Is anyone taking bets on how long before the first report of a critic of Vladimir Putin feeling a pinprick on the subway, followed some months later by cancer and death?

    --
    Ben "You have your mind on computers, it seems."
  30. Cancer Stem Cells by Blitz22 · · Score: 1

    So does this mean that they will be able to grow new organs from these cells but those will already have cancer and will only be somewhat useful? I know, RTFA.

    --
    If I went around claiming I was an emperor...they'd put me away!
  31. There is a difference by Weaselmancer · · Score: 1

    This seems like a better option.

    Well, the difference is that these are cancer stem cells. Cancer seeds, not cancer. From the article:

    MIT scientists and colleagues have found a way to create in the lab large amounts of cancer stem cells, or cells that can initiate tumors.

    If you could find a way to kill the seeds, then perhaps all the other techniques we are working on to kill the tumors will become irrelevant. Maybe the seeds are easier to kill than the tumors they sprout into. Prevention is the best medicine, after all.

    --
    Weaselmancer
    rediculous.
    1. Re:There is a difference by pathos49 · · Score: 1

      They did not prove these are stem cells, they just said they were. As for killing the seed, that is not a good way to think about cancer. Cancer can arise from a stem cell or from a differentiated cell. For example, there is little doubt that hepatocellular carcinoma arises from hepatocytes, a differentiated cell. On the other hand. some leukemias are believed to arrise from progenitor cells in the blood. Now are the progenitor cells stem cells?? That is a raging debate. Now in regards to needing cancer cells to study, well cancer cells are a moving target. While they arise from single cells, progressive generations are different. This is termed clonal expansion.

  32. Everything these days can give you cancer... by Kuvter · · Score: 1

    even these new stem cells.

    --
    "To be is to do." --Socrates
    "To do is to be." -- Aristotle
    "Do-Be-Do-Be-Do..." --Sinatra
  33. Re:New biological weapon? by heinousjay · · Score: 2, Funny

    Why am I so certain the Apple iCar would have one pedal, and you'd have to press a modifier button (on the steering wheel?) to use the brake?

    --
    Slashdot - where whining about luck is the new way to make the world you want.
  34. Oblig simpsons reference by kypper · · Score: 1

    How do you sleep at night>

    On top of a pile of money, with many beautiful women

  35. Viruses do this quite nicely. by PIPBoy3000 · · Score: 1

    HPV and other naturally occurring viruses cause cancer quite nicely. Of course, if you want a viral weapon, why not use Ebola which you don't have to wait years to see an effect? I realize mad scientists come in all sorts of colors and flavors, but killing people with cancer seems awfully slow (unless your country has a cure for cancer and others don't).

    1. Re:Viruses do this quite nicely. by milamber3 · · Score: 1

      HPV can cause cancer over a very long time and it's not definite that anything will even develop. With the kind of gene transfer they use to make these cancer stem cells you would almost instantly have cancer where ever the virus dropped it's payload. The field of gene therapy (transfer) is still young but sooner or later they will be very good at targeting specific areas or cells in the body. They may also have better transfection rates and even better cancer inducing genes. This leads to possibilities that something like Ebola could never give. I'm not sure I have a nefarious enough mind to figure out why targeted cancer might be useful over outright death by something like Ebola but I'm sure there is someone out there who could.

      Scratch that, I just thought of one. If you wanted someone dead and wanted it to look natural then you would never use Ebola. That would scream foul play. On the other hand, giving them a huge, inoperable brain tumor wouldn't look very suspicious. The only way to tell anything was done would be postmortem and even then it would have to be a very intensive investigation to find the inserted genes. And that's assuming they can't make the genes look like the natural mutations that bring about cancer normally. All this stuff is really far away from reality and in no way should it be used to put down the current science which should prove to be very useful in the study of cancer.

  36. slow? by peter303 · · Score: 1

    It might take months or years to kill.

    In that sense its a lot like AIDS was before there were any drugs. You knew you had a fatal time bomb in you but didnt quite know when and how.

  37. Re:Isn't this going in reverse? by treeves · · Score: 1

    For crying out loud, you're missing important plot points.

    --
    ...the future crusty old bastards are already drinking the Kool-Aid.
  38. eh pardon me Mr. MIT scientist by xednieht · · Score: 1

    But wouldn't it be better to do the opposite? I mean hell all we need is a few packs of smokes, a touch of this chemical, a touch of that chemical, and a pinch of high-dosage radiation and we can make our own cancer. It's unmaking cancer that is the trick no?

    --

    Hope is the currency of fools
  39. Re:Isn't this going in reverse? by quinspr70c0l · · Score: 2, Informative

    There are multiple advantages of using cancer cells in research. Stem cells are generally hard to come by. Cancerous versions of the cells tend to be tougher and grow much more rapidly enabling cell cultures to be easily shared among scientists. Normal cells tend to stop growing after they reach a certain density and form only a thing layer on a Petri dish. Cancer cells exhibit no such inhibitions. The first mammalian cells that could be cultured indefinitely were the HeLa which were cancerous. http://en.wikipedia.org/wiki/HeLa I would imagine that these cancerous stem cells would greatly aid stem cell research.

  40. Oh good. by reverendG · · Score: 1

    And here I was worried it would never happen.

    --

    Why should I argue rationally with someone being irrational? I'll just mock them instead.
  41. Another application by CrackedButter · · Score: 1

    for this is actually to solve the problem of human death because cancer cells are for all intents and purposes, immune to death since they block the shortening of the telomere with in their own cell structures, I can't remember what it is called but supposedly the science behind this would be to look at applying this ability to ourselves to block the degradation of our own telomeres, thus preventing old age death.

    1. Re:Another application by Daetrin · · Score: 1
      "for this is actually to solve the problem of human death because cancer cells are for all intents and purposes, immune to death since they block the shortening of the telomere with in their own cell structures, I can't remember what it is called but supposedly the science behind this would be to look at applying this ability to ourselves to block the degradation of our own telomeres, thus preventing old age death."

      Oh, that part is easy. You can even buy the stuff on the open market now. Unfortunately just eliminating cellular senescence isn't enough by itself to make you immortal. In fact there are worries that just restoring your telomeres without any other kind of treatment might make you more likely to get... cancer! :)

      --
      This Space Intentionally Left Blank
  42. Re:New biological weapon? by Choad+Namath · · Score: 1

    Big Oil only wants you to think that they're not practical. I'm sure they have plenty of them locked up with their stash of electric cars and air engines.

  43. Like polonium? by Geof · · Score: 1

    There are already plenty of very effective ways to cause cancer that are a lot easier, cheaper and more easily deliverable.

    Like polonium?

    Depending on who you are, there may be benefits to expensive and difficult.

    I wonder if this is hard to test for.

  44. Re:New biological weapon? by danpsmith · · Score: 1

    The Oil industry has used desktop-sized fusion devices for prospecting for decades. They are also commonly used as neutron sources for various scientific experiments. Heck, there are even teenagers building their own fusors in the basement. Now if you were talking about fusion devices capable of yielding a net power output at prices competitive with existing energy sources, then that is quite a different thing, but I don't think anybody has ever claimed to have achieved this, not even the cold-fusion crowd...

    Oh, he meant actual fusion. I'm so much of a geek I thought he was making a reference to this fusion on the desktop, and I was going to say, look, there's alphas or betas available already, what are you getting so fussy about?

    --
    Judges and senates have been bought for gold; Esteem and love were never to be sold.
  45. Could someone with relevant background clue me in? by Opportunist · · Score: 1

    I thought with the HeLa cells we got all we need? Immortal cancer cells that spread and divide ad infinitum.

    Is cancer some sort of infection? I thought it's a mutation gone wrong?

    --
    We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  46. Re:New biological weapon? by gronofer · · Score: 1

    Infectious cancer is apparently possible, check out "devil facial tumour disease".

  47. Collateral Damage by Mal-2 · · Score: 1

    If someone is really intent on taking out a certain target (thus committing the resources), but even more intent on causing no collateral damage (unlike the Litvinenko hit), this method might make a bit of sense. Spend a lot of money, maybe you kill the guy or maybe you don't, but you don't harm anyone else either way. I can't think of any situations where this is less resource-intensive than assassination, but maybe Tom Clancy can.

    Mailing Anthrax would take a very large box indeed.

    Mal-2

    --
    How is the Riemann zeta function like Trump rallies? Both have an endless number of trivial zeros.
  48. Re:Isn't this going in reverse? by Hrshgn · · Score: 1

    I read the original article and find the press release from MIT hypes the research too much.

    The original article just indicates that different cells inside a tumor have different tumorigenic behavior. As mentioned above, getting cancer cells into culture and multiplying them is nothing new, it's what researches do every day since cancerous cells grow indefinitely and are therefore a very convenient tool for cellular studies of all sorts, not only cancer.

    The authors don't even use the term "stem cell" in their article. I guess MIT just wanted to jazz it up a little bit by using buzz words.

  49. And the novelty is what?? by pathos49 · · Score: 1

    So agroup of scientists have inserted some genes into a primary cell and created a cancer cell line????? The just reproved that cancer requires inititation AND promotion. Lame

  50. Re:New biological weapon? by LokiSnake · · Score: 1

    Slashdotters are lazy. You need to link it for them, like so: Devil facial tumor disease