Slashdot Mirror


Woman Suffers Significant Weight Gain After Fecal Transplant

Beeftopia (1846720) writes In a case reported in the journal Open Forum Infectious Diseases, a woman suffering from a drug-resistant intestinal infection gained 36 pounds after receiving a fecal transplant from her overweight daughter. Previous mouse studies have shown thin mice gain weight after ingesting fecal bacteria from obese mice. The woman previously was not overweight. After the procedure, despite a medically supervised liquid protein diet and exercise regimen, the woman remained obese. Her doctor said, "She came back about a year later and complained of tremendous weight gain... She felt like a switch flipped in her body, to this day she continues to have problems... as a result I'm very careful with all our donors don't use obese people."

378 comments

  1. Comment removed by account_deleted · · Score: 5, Funny

    Comment removed based on user account deletion

  2. Okay, so... by Anonymous Coward · · Score: 4, Insightful

    Figure out which bacteria the obese patients have in common that the thin ones don't, and figure out a way to eliminate it.

    1. Re:Okay, so... by Megane · · Score: 4, Informative

      Fecal transplants from thin people to fat people causing weight loss is actually a thing. What I hadn't heard of before is the reverse, but I am certainly not surprised.

      --
      #naabhaprzrag, #sverubfr-000, #agi-fcbafberq, negvpyr[pynff*=' negvpyr-ary-'] { qvfcynl: abar !vzcbegnag; }
    2. Re:Okay, so... by Anonymous Coward · · Score: 5, Interesting

      Figure out which bacteria the obese patients have in common

      They've done some perliminary studies, and one major difference is the proportion of Firmicutes to Bacteroides. Fewer Bacteroides and more Firmicutes are correlated with being obese. Those are borad classes, though, and not particular strains, and it's not clear if it's the presense of Firmicutes, or the abscence of Bacteroides which is related to obesity.

        Bacteroides likes to eat complex polysaccharides, like those found in many plants, so it's speculated (but not known) that a diet high in plant polysaccharides would promote the presence of Bacteroides, and correspondingly reduce the number of Firmicutes

    3. Re:Okay, so... by Z00L00K · · Score: 1

      Probably because the weight loss industry would work against such methods - they will lose the customers.

      --
      If builders built buildings the way programmers wrote programs, then the first woodpecker would destroy civilization.
    4. Re:Okay, so... by Virtucon · · Score: 0

      So eating salads and vegetables works.

      --
      Harrison's Postulate - "For every action there is an equal and opposite criticism"
    5. Re:Okay, so... by Anonymous Coward · · Score: 5, Interesting

      The whole point is many skinny people violate this law but do not get obese.

      I do and the way I eat absolutely upsets a few larger people I know.

      burgers, doughnuts, eating out a lot, snacking all the time, yet I'm a solid 155lbs at 5'11 with a desk job as a software developer sitting all day. Nothing I do changes my weight and I'm a very small framed athletic looking individual who takes about 2 shits a day if it matters to anyone.

      I also drink loads of coffee and soda, then sit around idle and program.

      So the law is kinda bullshit for some of us.... This whole bacteria talk is about trying to bestow traits like mine unto people who can't lose weight without literally starving it out of them with your "law".

    6. Re:Okay, so... by peragrin · · Score: 1

      actually it isn't. some people only need 1,000 calories a day, others need 2,000 extremely active people need 3-5 thousand.

      Eating less than a thousand calories a day actually makes you gain fat as your body stores it.

      I run about 1,200 calories a day and I can barely maintain my weight. Yes that is two slices of toast for breakfast, a glass a milk. a 140 calories snack bar, and 140 calorie yogurt for lunch, and a healthy dinner of salads, and usually chicken, but I mix up the protein. Very rarely do i eat anything after dinner,

      Figure out what to cut out of that. If I could figure out a way of inverting it and eat the big meal in the morning I might be better off but the timing sucks.

      --
      i thought once I was found, but it was only a dream.
    7. Re:Okay, so... by Anonymous Coward · · Score: 1

      Obviously it isn't the whole law: wood has quite a lot of calories and burns nicely in a stove. But try getting fat from eating sawdust.

    8. Re:Okay, so... by Opportunist · · Score: 3, Interesting

      Funny that this law doesn't apply to everyone. I know a guy who literally doesn't eat. He inhales. I actually doubt that he chews. As for "exercise", there's very little outside the area of mouse clicking and occasional trips to the fridge to get a new soda.

      One should assume that he's a lardball. He isn't. Quite the opposite.

      There is nearly certainly some other reason behind some people's weight that cannot be explained with "too much food and too little exercise" alone.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    9. Re:Okay, so... by PRMan · · Score: 3, Interesting

      Figure out what to cut out of that. If I could figure out a way of inverting it and eat the big meal in the morning I might be better off but the timing sucks.

      Easy. The carbs.

      Toast = carbs. Milk = carbs. Snack bar = carbs. Yogurt = carbs. For two meals every day, your protein to carbs ratio sucks. Eat 125g of carbs per day or less. Count it out. Then, eat as much protein and vegetables as you like. Meat, eggs, cheese, nuts, carrots, celery, pickles, etc.

      Here's what I ate on my way to losing 70 pounds in 9 months:

      Breakfast: Bacon, eggs fried in butter, hot or iced tea. Limit myself to one slice of toast, one piece of fruit or a half cup of juice (about 4 ounces), if at all

      Lunch: This is where I eat most of my carbs. As a programmer, I must have one Coke (40g carbs) in the middle of the day to function properly. Beyond that I would eat something with only about 30g-40g of carbs.

      Dinner. Again, eat about 30-40g of carbs max, depending on what I ate the rest of the day. If I need to snack after dinner, it's meat, eggs, cheese, nuts, carrots, celery, pickles, etc.

      The weight dropped off effortlessly, despite me eating as much as I wanted. The problem is that our modern society has shifted food to where our balance is completely off compared to how we were designed.

      --
      Peter predicted that you would "deliberately forget" creation 2000 years ago...
    10. Re:Okay, so... by BarbaraHudson · · Score: 1

      Obviously it isn't the whole law: wood has quite a lot of calories and burns nicely in a stove. But try getting fat from eating sawdust.

      What, nobody told you what that "filler" is in all those foods imported from China?

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    11. Re:Okay, so... by Anonymous Coward · · Score: 0

      Have you actually measured the calories you eat?

    12. Re:Okay, so... by Wycliffe · · Score: 1

      Don't assume that he's healthy though. My mom teaches 4th grade and was complaining once that the mouse they
      were feeding nothing but sugar was losing weight while the mouse they were feeding healthy was gaining weight.
      I told her it probably was because the mouse eating nothing but sugar was slowly dying.

    13. Re:Okay, so... by BradleyUffner · · Score: 0

      The whole point is many skinny people violate this law but do not get obese.

      No, they don't. If they did somehow take in more calories then they put out without gaining weight they would be destroying matter and energy, which is physically impossible in our universe. Our bodies are not some magical boxes where the laws of physics suddenly stop applying.

    14. Re:Okay, so... by Anonymous Coward · · Score: 0

      That statement is true, but is an oversimplification.

      In this case - if you noticed, they carefully monitored the incoming calories - there *must* have been a drastic change in the number of calories the patient used, by definition, because she started gaining weight on the same or fewer calories.

      So before the transplant, she must have been burning many more calories at rest than after the transplant.

    15. Re: Okay, so... by smaddox · · Score: 2

      If he's drinking multiple non-diet sodas a day, he's practically guaranteed to be above a 2000 cal diet.

      This article is not science. A single uncontrolled data point is far from convincing. There appears to be some legitimate evidence from studies in mice that gut bacteria transplants can have an significant effect on weight (on phone so no ref), but it's not definitively proven.

      This particular case could be explained in a thousand other ways.

    16. Re:Okay, so... by ShanghaiBill · · Score: 3, Informative

      Here's what I ate on my way to losing 70 pounds in 9 months:

      Losing 70 lbs in 9 months is not hard. The important question is: How much did you weigh five years later?

    17. Re:Okay, so... by itzly · · Score: 1

      Eating less than a thousand calories a day actually makes you gain fat as your body stores it.

      No. It makes no sense for the body to store fat when all the energy is needed to sustain basic metabolism.

    18. Re:Okay, so... by Anonymous Coward · · Score: 0

      You did not read what the previous poster said, you added in some of your own assumptions.

      Let's assume you are correct in what you say (I don't agree, but it's not important, assume you are correct). Poster did not say that you and fat guy should eat the same diet and the world will be fair. He said, if a fat person does not like their weight, they should eat less. And that is true. They should not look over at your plate and demand the same, they should eat less of what is on their plate.

      They will lose weight. You don't need to.

    19. Re:Okay, so... by itzly · · Score: 1

      Yogurt = carbs

      Plain yogurt has 45% of the calories from fat, 30% from carbs, and 25% from protein.

    20. Re: Okay, so... by sonicmerlin · · Score: 2

      It's called a case study. It is in fact science. It doesn't "prove" anything but illuminates possibilities for further research.

    21. Re:Okay, so... by itzly · · Score: 1

      If they did somehow take in more calories then they put out without gaining weight they would be destroying matter and energy

      When you say "take in", you mean the food that people put in their mouths. But not all nutrients that people put in their mouths are absorbed in the blood stream. Some are passed in the stools, and others are metabolised by the gut bacteria.

    22. Re:Okay, so... by itzly · · Score: 1

      So before the transplant, she must have been burning many more calories at rest than after the transplant.

      Or her gut didn't absorb all the nutrients that passed by.

    23. Re:Okay, so... by DexterIsADog · · Score: 5, Insightful

      The whole point is many skinny people violate this law but do not get obese.

      No, they don't. If they did somehow take in more calories then they put out without gaining weight they would be destroying matter and energy, which is physically impossible in our universe. Our bodies are not some magical boxes where the laws of physics suddenly stop applying.

      Um, no, you're wrong. One possibility is that their bodies excrete a higher percentage of the food they take in without metabolizing it. No magic involved.

      I think you have a too simplistic view of human bodies. They are not machines that perfectly process whatever is put into them.

    24. Re:Okay, so... by DexterIsADog · · Score: 1

      Obviously it isn't the whole law: wood has quite a lot of calories and burns nicely in a stove. But try getting fat from eating sawdust.

      What, nobody told you what that "filler" is in all those foods imported from China?

      I thought the filler was melamine. Or lead.

    25. Re:Okay, so... by Anonymous Coward · · Score: 1

      Wrong
      Mass = Initial Mass + Mass In - Mass Out

      Mass is very weakly correlated with caloric energy even when only considering things people typically ingest.
      Mass Out is difficult to calculate (or measure) directly. People eject mass in a lot more ways than pissing and shitting. You can calculate it by measuring Mass, Initial Mass, and Mass In. Then you can determine ways to maximize Mass Out and minimize Mass In. Eating less will minimize Mass In. But physical exertion is not always directly correlated with Mass Out. Increasing physical exertion (or minimizing eating) beyond certain points, or doing the wrong type of physical exertion / eating (or not eating) the wrong types of food will cause the body to retain mass. Those crossover points and those activities and foods are different for each person. The only way to determine them is indirectly, through experimentation and the measuring of their effect on Mass Out.

      You absolute cannot say a human is eating x calories and "burning" y calories with z activity, then determine weight loss or weight gain via the difference between x and y. The ONLY way you could even make a decent ESTIMATE with this is if you threw a person's piss, shit, sweat, etc. into a calorimeter and compared that to the caloric value of things ingested and correlated it into change in mass. This would tell you y. Otherwise, you don't know y, and you're guessing at it via some fast and loose approximation of z (based on a person's age, weight, height, exercise journal, etc.). By knowing y you could experimentally vary z, and all the variance per person (age, weight, height, exercise journal, etc.) wouldn't matter.
      Joe (5'10", 230 pounds, 43 years old) could do "30 minutes" of "light cardio" a day, and no matter how he (age, weight, etc.) or his definition of "30 minutes" or "light cardio" differ from Steve, his results on varying z would be directly applicable to him and directly measurable. Further, the variance in z itself would be directly quantifiable and qualifiable for Joe. Joe's idea of "20 minutes" is measured in the exact same way as his idea of "30 minutes", whereas Steve may measure the start and stop points differently. Joe's idea of "light", "moderate", "intense" are consistent to him, whereas Steve may consider Joe's "moderate" to be the same as his "light".

      The bottom line is you can't make blanket statements. You have to actually measure calories in AND calories out, for a given person, and then experimentally vary activity. And ideally, you would be measuring mass instead of calories.

    26. Re:Okay, so... by wiredlogic · · Score: 3, Informative

      Bacteroides likes to eat complex polysaccharides, like those found in many plants, so it's speculated (but not known) that a diet high in plant polysaccharides would promote the presence of Bacteroides, and correspondingly reduce the number of Firmicutes

      What would be more interesting is if these bacteria actually influenced their host's behavior to drive more consumption of sugars. I'm skinny and have never had a strong desire to consume sweets. The majority of the overweight population who can't naturally control their consumption of high-energy foods seem alien and puzzling to me.

      --
      I am becoming gerund, destroyer of verbs.
    27. Re:Okay, so... by Luckyo · · Score: 1

      You can't extrapolate complex issues like this. This is what happened with "let's have a medicine to change certain cholesterol levels" that cost enormous amount of money in trials and crashed and burned because it didn't do what extrapolation suggested it should do.

    28. Re:Okay, so... by Anonymous Coward · · Score: 0

      You're thinking of mass. Our bodies are not some magical boxes where every calorie in is used or kept. We eject mass on a regular basis. There is no definition of how the human body "uses" calories. Such a definition would vary wildly per person, and would rely on burning their shit and piss to measure it.
      All measures of calories "needed" for a given person are generalized and approximated. All measures of calories "used" for given activity levels are generalized and approximated. All activity levels are generalized and ambiguously defined.

    29. Re:Okay, so... by Luckyo · · Score: 1

      That is not what is implied here. To get fat from energy, you need said energy to be absorbed form your gut into your bloodstream.

      In this case, it appears that certain kind of gut microbiome may consume this energy without transferring it to the bloodstream. In other words, the suggestion that "what you eat ends up in you the same way it does in that other person" is factually incorrect - we already know that microbiome is individual and significantly impacts your ability to absorb nutrients.

      The question here is how much of a difference it is.

    30. Re:Okay, so... by Hognoxious · · Score: 1

      Some people's digestions are more efficient than others'. That's not in dispute.

      But nobody's is greater than 100%. And nobody's is less than 0%, for long.

      The amount you eat is still the baseline.

      --
      Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    31. Re:Okay, so... by BarbaraHudson · · Score: 1
      Or human hair, ink, and contraceptives.

      In recent years, for instance, China’s food safety scandals have involved everything from fake baby milk formulas and soy sauce made from human hair to instances where cuttlefish were soaked in calligraphy ink to improve their color and eels were fed contraceptive pills to make them grow long and slim.

      Human hair to make fake soy sauce? Who was crazy enough to think of this in the first place?

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    32. Re:Okay, so... by Anonymous Coward · · Score: 0

      Eating less than a thousand calories a day actually makes you gain fat as your body stores it.

      What you describe is commonly called "starvation mode" and has no medical substantiation behind it.

      You need to (1) figure out your basal metabolic rate (i.e. how many calories your body needs per day, which varies from person to person) and (2) you need to be super-accurate about counting calories. Most people are terribly inaccurate for various reasons (forget to count snacks, or are under a delusion that certain food types don't count, and etc.).

      Once you get those two items down, eat a little below it and you WILL lose weight. Guaranteed.

    33. Re:Okay, so... by Hognoxious · · Score: 1

      Yes, makes you wonder what they were trying to achieve.

      --
      Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    34. Re:Okay, so... by turning+in+circles · · Score: 1

      Figure out which bacteria the obese patients have in common that the thin ones don't, and figure out a way to eliminate it.

      Sounds easy, but there are more bacterial cells in your body than eukaryotic (human) cells by a factor of 10, and unlike the human cells that all have the same DNA, the bacteria are different. By the way, if you want to know what various types of bacteria are in your personal stool, you can go to American Gut and pay someone $99 to analyze your shit. The answer, however, will be fairly general, because no one's sequenced all the different bacteria there.

      --
      Might as well face it I'm addicted to data.
    35. Re: Okay, so... by ceoyoyo · · Score: 0

      It isn't science. It's something medical doctors do and some of them think is science.

      You're right though, it is certainly an interesting anecdote that suggests approaches for actual science to investigate.

      There is, in fact, scientific evidence in animals that gut microbiota and fecal transplants can affect weight. This is the first report I've heard that it might work in humans.

    36. Re:Okay, so... by angel'o'sphere · · Score: 2

      Actually, it does not.

      The problem your parent points out is only *one* of the options. The more general situation is that some humans, most of them obese, harbour gut bacterias similar to cows.

      Hence they break up fibers, and salat and vegetables are very rich on fibers in relation to their carb level.

      In other word they have more than 2x the kcals than rated on the label or in a diet book, if you have thise bacteria.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    37. Re:Okay, so... by ceoyoyo · · Score: 1

      When most people say "calorie" they don't mean the amount of energy you'd get out of some food if you put it in a bomb calorimeter and completely combusted it. They mean the estimate you see on the packaging of how much energy your body might absorb from the food, which seems to vary wildly in practice.

      To further complicate matters, when Americans say "calorie" they're actually talking about a unit that is equivalent to 1000 calories in the rest of the world.

    38. Re:Okay, so... by angel'o'sphere · · Score: 1

      Perhaps you are just a good/intensive programmer?

      Heavy mental work burns as much energy as any heavy body work. (Except for true athletes, like cyclists, marathon runners etc.)

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    39. Re:Okay, so... by Jack+Greenbaum · · Score: 1

      A logical conclusion is that obese people's fecal fauna may impact how efficiently they can use those calories they eat.

    40. Re:Okay, so... by itzly · · Score: 2

      Between 0% and 100% is enough variation left. Even a 5% difference on a 2500 kcal diet equals 15 pounds of fat after a year.

    41. Re:Okay, so... by angel'o'sphere · · Score: 1

      To get fat from energy, you need said energy to be absorbed form your gut into your bloodstream. Your idea how digesting works is wrong.

      Bacterias don't 'transfer energy' to the body. They simply split stuff up and the body takes the waste/remains of that splitting.

      E.g. fat and sugar and proteins are taken by the blood stream and further used/stored/burned by the body! No bacteria involved in converting/burning carbs into 'energy'.

      Imagine the bacteria simply as a horde of little cooks with nice cutting knives, cutting up the stuff you would shit out otherwise.

      Funnily, except for the exact words, the rest of your comment is right.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    42. Re:Okay, so... by BradleyUffner · · Score: 0

      Um, no, you're wrong. One possibility is that their bodies excrete a higher percentage of the food they take in without metabolizing it. No magic involved.

      I think you have a too simplistic view of human bodies. They are not machines that perfectly process whatever is put into them.

      How is "excreting" not putting calories out? It doesn't matter how the calories come out, be it exercise, taking a crap, or cutting off your arm, those are still calories that leave the system.

    43. Re:Okay, so... by BradleyUffner · · Score: 1

      Taking a crap counts as "calories out".

      Everything that enters our body either stays in it, or is removed from it in some way. It's a zero sum game with the rules enforced by physics.

    44. Re:Okay, so... by angel'o'sphere · · Score: 1

      Milk and yogurt have not much carbs.

      Carrots on the other hand have quite a nice amount.

      Your idea makes bottom line sense, especially being still high carb around lunch, so your brain has energy.

      Regarding carb and calorie values, I strongly suggest to read various sources. E.g. the quick googeling I made about yogurt, the first hit claimed 24g carbs for 100g yogurt. Which is actually nonsense. The other hits where around 4g, which still sounds high, but after all the bacteria producing the yogurt might have enriched it, no idea, did not dig into it. Then I had a hit that put Yogurt in a table with do's and don'ts on the don't side, without explanation.

      Anyway, yogurt can not have much carbs, as it is just 'fermented' milk, which has not much carbs either.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    45. Re:Okay, so... by BradleyUffner · · Score: 1

      When you say "take in", you mean the food that people put in their mouths. But not all nutrients that people put in their mouths are absorbed in the blood stream. Some are passed in the stools, and others are metabolised by the gut bacteria.

      And when I say "put out" I include everything that leaves the body, including unprocessed food that ends up in the toilet.

      So between "taking in", "putting out", and "storing" everything eventually adds up to 0. It doesn't matter how efficient your body is at all for this calculation, because efficiency only effects the distribution of "putting out" vs "storing". It's a zero sum game with the rules enforced by physics.

    46. Re: Okay, so... by angel'o'sphere · · Score: 1

      Wow, someone who proclaims he knows what science is and what not and throws in the new /. anathema 'anecdote' believes: you need a special scientific study to proof that transplanting bacteria from one human to the other works.

      You wrote it yourself: it works in animals. What exactly do you think might prevent it from working in humans? Hu!????

      Why do people always de,and studies and proofs for no brainers? That is beyond me!

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    47. Re:Okay, so... by angel'o'sphere · · Score: 1

      Have the 'right' gut bacteria and it is no problem. Termites do it. (Eating cellulose mainly)
      Cows do it ... goats do it, I think even horses could do it.

      The article is exactly about the effect hat 'wood' particles 'ordinary people' don't digest, are digested by 'some' obese people.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    48. Re: Okay, so... by ceoyoyo · · Score: 0

      Do you just post rants on Slashdot for the fun of it?

      The OP was talking about this story, which is a case report. N of 1, in uncontrolled circumstances. That is not science. It does, however, agree with actual science, done in animals, and suggests that those animals studies may be applicable to humans.

      You're aware that mice are not humans right? Dozens of promising drugs and other treatments that work well in petrie dishes and animals fail human clinical trials every year. In particular relevance to this story, rodent digestion, gut microbiota, diet and metabolism are quite different from humans.

    49. Re: Okay, so... by angel'o'sphere · · Score: 1

      You are aware we talk about bacteria?
      Especially gut bacteria.

      The question if they live in mice or humans has nothing to do with it. As we are talking about 'guts'.

      Also we are not talking about transferring 'gut' bacteria from mice to humans, but from humans to humans.

      Also we have thousands if such transplants in humans where only the 'desired' bacteria where transferred.

      The idea that transferring undesired gut bacteria in mice from gut to gut does work but in humans it does not is so unscientific it is beyond believe. If you need a special study to be 'convinced' go ahead.

      And to answer your question: yes, I like to rant about such idiotic stand points or ideas.

      50 years ago people believed Mars was harboring live, because of its colour changes. Then viking landed and they thought, "oh, no life." Suddenly the idea was up again the whole universe is lifeless, and earth is the only planet harboring life. Now it is widely assumed that life might be everywhere.

      What is my point? Instead of claiming everything is special and you need to find common roots, obviously it is much more straight forward to assume everything works the same everywhere. That does not exclude differences in the details.

      But people like you always claim: you need a scientific study to be 'sure' that they 'behave the same'. I say: the laws of physics are everywhere the same.

      If transfer of 'bad gut bacteria' in any species in existence does not work: THEN I WOULD BE SURPRISED.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    50. Re:Okay, so... by Anonymous Coward · · Score: 0

      burgers, doughnuts, eating out a lot, snacking all the time, yet I'm a solid 155lbs at 5'11 with a desk job as a software developer sitting all day. Nothing I do changes my weight and I'm a very small framed athletic looking individual who takes about 2 shits a day if it matters to anyone.

      Just you wait another 10 or 15 years, buddy.

    51. Re:Okay, so... by DexterIsADog · · Score: 1

      Oh lord, I don't think you even understand what you wrote. I'm not a grade school teacher; figure it out for yourself.

    52. Re:Okay, so... by Anonymous Coward · · Score: 0

      Sounds like me, till I found I I had celiacs.

    53. Re:Okay, so... by BradleyUffner · · Score: 0

      If you don't understand the basics about physics then there really isn't much point in continuing this conversation. Pretty much anyone who finished highschool should be able to understand what I'm saying.

    54. Re:Okay, so... by Anonymous Coward · · Score: 0

      Nothing in life is that simple, the bacteria's effect will be subjective.

    55. Re:Okay, so... by Anonymous Coward · · Score: 0

      The whole point is many skinny people violate this law but do not get obese.

      No, they don't. If they did somehow take in more calories then they put out without gaining weight they would be destroying matter and energy, which is physically impossible in our universe. Our bodies are not some magical boxes where the laws of physics suddenly stop applying.

      Um, no, you're wrong. One possibility is that their bodies excrete a higher percentage of the food they take in without metabolizing it. No magic involved.

      I think you have a too simplistic view of human bodies. They are not machines that perfectly process whatever is put into them.

      The people who says this also forget that you need to account for ALL inputs and outputs in order to do a mass-energy balance: a skinny person could have an inefficient gut where a lot of undigested food going out with the waste stream while a fat person could be hampered by a very efficient gut. Your hunger impulse mostly just tells you that you stomach is empty, it's not like it's an actual fuel gauge keeping count of the calories.

    56. Re: Okay, so... by ceoyoyo · · Score: 1

      Transferred gut bacteria from donor to recipient mouse can have effects on weight. There are scientific studies to support that.

      Transferring bacteria from the guts of one human to another seems similar, but it is not necessarily. As I said before, humans have different gut bacteria, different digestive systems and different metabolisms. Effects that are noted in mouse fecal transplants will not necessarily be present in human fecal transfers. You can certainly take some human poop and shove it into another human, but you should not assume it will have the same effects as such a procedure does in a mouse, without scientific testing.

      However, if you believe effects demonstrated in mice are straightforward to transfer to humans, I'd like to sell you some great patents!

    57. Re:Okay, so... by Anonymous Coward · · Score: 0

      Not exactly, they will continue to sell shit.

    58. Re:Okay, so... by Grishnakh · · Score: 1

      You're overgeneralizing. I'm skinny and I definitely have a strong sweet tooth. As long as I exercise enough and avoid HFCS and crap like sodas, I stay skinny. (This isn't to say that I keep my sugar consumption low; I do eat quite a bit of sugar, but it's all sucrose and carbs, and I certainly don't eat like a bird.)

      Different people have radically different digestive systems and tolerances and metabolisms; that's the bottom line.

      Given the sedentary lifestyle of much of modern society, it seems there should be medical research into making our digestive systems *less* efficient.

    59. Re:Okay, so... by Twinbee · · Score: 1

      What he means is that those calories that would otherwise make you fat, are instead excreted. And that some people manage it better than others.

      --
      Why OpalCalc is the best Windows calc
    60. Re:Okay, so... by Anonymous Coward · · Score: 0

      You aren't looking hard enough then. Those fruity-ass yogurts that everyone are all the rage over these days are packed full of sugar. You have to find plain ol natural, free-ranged, gluten-free, trade neutral, all-organic, locally-sourced, hipster-approved yogurt to get the criteria you are assuming.

    61. Re:Okay, so... by DexterIsADog · · Score: 1

      You're continuing to pretend that you understand what you wrote. That is ADORABLE!

    62. Re:Okay, so... by smellsofbikes · · Score: 1

      This is interesting, because my diet, such as it is, is almost exactly the opposite. I eat just over 1 gram per kilogram of body weight of protein, and about the same amount of fat, and then fill in the rest with carbs. But I'm a bike racer, so in the winter that may be 3000 calories of 70% carbs, where in mid-summer that sometimes stretches to 6500 calories a day, close to 85% carbs -- and I can't manage to get through the summer without losing 10 kilos, at which point I'm below 6% body fat and health issues start showing up and I have to start adding some fats.
      Metabolism is weird.
      One of my microbiology professors used to say that he felt humans were giant life support units for mobile ecosystems. He felt that much of what we think and feel is actually manipulated by our bacteria to benefit them and deter invasion from other bacteria.

      --
      Nostalgia's not what it used to be.
    63. Re:Okay, so... by Anonymous Coward · · Score: 0

      who takes about 2 shits a day

      That's one shit a day too many. You should talk to your doctor.

    64. Re:Okay, so... by GerryGilmore · · Score: 1

      I don't have the links handy, but The Economist magazine has been regularly reporting for several years that the bacteria in our gut contains *trillions* of bacteria. The particular mix and types of bacteria comprise what is known as the "micro-biome". It is now known, without a doubt, that these bacteria have a *radical* effect on how food is metabolized in the human body. So, the old saw about "just eat less and you will lose weight" is not strictly true. BTW, I say this as a formerly fat person who did lose lots of weight by eating less, but that does not alter the reality of how our gut bacteria has a profound impact on not just our weight, but health in general. Very, very much worth investigating fellow /.ers...

    65. Re:Okay, so... by Anonymous Coward · · Score: 0

      The whole point is many skinny people violate this law but do not get obese.

      I do and the way I eat absolutely upsets a few larger people I know.

      burgers, doughnuts, eating out a lot, snacking all the time, yet I'm a solid 155lbs at 5'11 with a desk job as a software developer sitting all day. Nothing I do changes my weight and I'm a very small framed athletic looking individual who takes about 2 shits a day if it matters to anyone.

      I also drink loads of coffee and soda, then sit around idle and program.

      So the law is kinda bullshit for some of us....

      You should check your blood sugar.
      I was the same way... turns out it was because I am what you would call "diabetic as all Hell".

    66. Re:Okay, so... by TheNarrator · · Score: 3, Informative

      Good find! Here's an interesting study on how over-activation of Toll-Like Receptor 5 by certain bacteria was highly correlated with obesity:

      http://www.ncbi.nlm.nih.gov/pu...

    67. Re:Okay, so... by thegarbz · · Score: 1

      Health and weight are not correlated within a normal range. Chubby people can be more healthy than thin people.

      The only place they are correlated is in anorexic people and obese people. For someone my height the uncorrelated range is 65 to 110 kg, and even then it goes out the window if you do something strange like zero movement (no muscles) or are a gym junkie (way above normal distribution of muscle to fat) which is where the BMI definition of "normal" fails.

    68. Re:Okay, so... by ConceptJunkie · · Score: 1

      It also depends on how old you are. If you are in your early 20s, this is pretty normal. If you are in your 40s, I'd be very surprised and a little jealous.

      --
      You are in a maze of twisty little passages, all alike.
    69. Re:Okay, so... by beelsebob · · Score: 1

      Congratulations, you didn't read the article. As you see, you are not the only thing digesting what goes in your mouth. It's entirely possible that said skinny person could consume 3500 calories, have their gut fauna convert 1700 of it into undigestible (by human) chemicals, and end up with a resulting actual digested intake of 1800 calories.

      This is the point - you can not simply measure the number of calories that go into your mouth, you have to measure how many actually end up in the blood stream.

    70. Re:Okay, so... by EthanBernard · · Score: 1

      Doesn't that mean that if one is counting calories, one should only eat the shit of fat people? ;)

    71. Re:Okay, so... by beelsebob · · Score: 1

      Then your argument has no usefulness to it. If you simply assert calories in minus calories out equals calories gained, you don't say anything that's useful to anyone. That's because calories out appears to be impossible to measure in its current state. It appears that bacterial fauna is a significant player in what makes up calories out, that's the point of this article.

    72. Re:Okay, so... by beelsebob · · Score: 1

      Milk has a huge amount of lactose in it - i.e. sugar, i.e. carbs.

    73. Re:Okay, so... by BigIrv · · Score: 1

      Can I interest you in being a fecal donor?

      --

      --Good morning fellas; Hand me that thing; Boy, this work's hard; Guys, break's over.
    74. Re:Okay, so... by Brulath · · Score: 1

      It's getting harder to find yoghurt not labelled low-fat in supermarkets (in Australia at least); the vast majority choose to reduce total fat content to minimal levels and fill in the flavour void with sugar. A generic supermarket yoghurt is 5g fat 29g sugar 30g carb, marking itself as 2% fat. You seem to have to aim for full-fat Greek yoghurt for anything approaching a 10g fat to 6-7g carb ratio. So the chances that he was eating a low-carb yoghurt are pretty low.

    75. Re:Okay, so... by Anonymous Coward · · Score: 0

      Worse, it would taste better than those pricey Weight Watchers meals, lo-fat potato chips, and "health drinks" that get hawked in magazines filled with pictures of women who'd never *read* the magazine, with perfect nails and dresses that would never fit the readers, who've somehow inflated their chests with helium instead of real flesh to avoid the need for actual underwires, and with all the tips on "how to revolutionize your sex life" for readers who get exhausted getting up for the remote control.

      I'm a bit cranky on the weight loss industries, because I spent way too long *feeding* some of those lard butt family members in my wife's family.

    76. Re:Okay, so... by Skuld-Chan · · Score: 1

      The one obese person I work with (also a programmer) - I always see him eating terribly (candy, sugary drinks, chips etc) - the only exercise he gets is walking from his door to his car and from his car to his desk, and he's gaining weight like crazy - easily another hundred pounds since I first met him. He's big enough that when the company sent him to a convention they had to buy two plane tickets for his two seats. At lunch without fail he always picks the worse thing you could get from the various cafe's near by (like if there was a 500 calorie meal and a 1000 calorie meal - he'll always go for the 1000 calories).

      I know when I was 20-30 I could eat whatever I liked and I was a skinny beanpole. After 30 though I really do have to watch what I eat - I'm guessing my metabolism slowed down. I do walk or ride my bike to work, and I used to go to the gym for about 2 hours a week (really messed up my shoulder in a bicycling accident...) - but yeah I can't sit there and snack all day without gaining serious weight anymore.

      The younger guys who come to work for us - some of them eat like that and over time I've notice them get rounder and rounder as they get older :(.

    77. Re:Okay, so... by Evtim · · Score: 4, Interesting

      There is something to what you say. My own experience was that once the gut flora got out of balance, yeast took over.

      During those few years of yeast overgrowth I developed very weird craving for sugars were often I won't be able to go to sleep [and shake like I am dying of starvation] if I did not eat sweet. Once the problem was identified I was put on no sugar at all diet. It took some discipline in the beginning, but to my delight once the yeast began dying [regular lab tests showed that] this maniacal cravings just disappeared and did not come back [1 year so far].

      So there is something about this. The guys in our intestines seem to have profound effect on many, many things in our physiological and psychological health.

      Tully, the old saying "tell me what you eat and I'll tell you who you are" seems to be spot on. During one of my doctor's visit I quoted the fad line "Well, those guys are sometimes called the second genome, right?"

      To which the doctor banged with her fist on the table and said "No, they are the first genome! They got more genes than us, their network of biofilm comprises an actual organ [without which we will be dead] , making it the largest organ in the body, 60% of your immune system happens in the intestine. Those guys can make us sick, the can cure us, they can make us crazy. And they were doing that job well before Homo Sapiens came to be. They are the first!"

    78. Re:Okay, so... by Monkey-Man2000 · · Score: 1

      Different people have radically different digestive systems and tolerances and metabolisms; that's the bottom line.

      That's partly the point, apparently a big part of the differences in digestive systems is the balances and type of gut bacteria we have.

      --
      This post was generated by a Cadre of Uber Monkeys for Monkey-Man2000 (603495).
    79. Re:Okay, so... by Monkey-Man2000 · · Score: 1

      You can't extrapolate complex issues like this.

      Why not? There ARE researchers looking at these issues because it's increasingly well-known that parasites can influence their host's behaviors.

      --
      This post was generated by a Cadre of Uber Monkeys for Monkey-Man2000 (603495).
    80. Re:Okay, so... by Anonymous Coward · · Score: 0

      Calories are only an estimate of the energy in food. In truth there's far more in it than we measure. Some people may be more or less efficient at absorbing it. As a result some people might well gain 4000 kcal from 2000kcal of food, or 400 kcal from 2000 kcal. Plus not everyone's bodies use the energy in the same way, so some people might burn off 2000 kcal a day more than someone else and therefore be able to eat double the amount without gaining weight. Excercise is one way to do that, but the resting energy use isn't neccessarily the same for everyone so someone could be burning double the amount of the person sitting next to them simply sitting at a desk.

    81. Re:Okay, so... by AmiMoJo · · Score: 1

      Can't I just... You know, drink some bleech or something to kill those bastards off? Or alcohol, alcohol kills bacteria, right? That's why they clean wounds with it!

      Reminds me of that scene in Armies of Darkness where Ash pours boiling water down his throat. Hay, that's an idea...

      --
      const int one = 65536; (Silvermoon, Texture.cs)
      SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    82. Re:Okay, so... by DexterIsADog · · Score: 1

      Your post has nothing to do with mine, so I can only conclude that you responded to the wrong one.

    83. Re:Okay, so... by Luckyo · · Score: 1

      I didn't say what you suggest I said. Your interpretation is strange to say the least.

      "Gut" does not equal "bacteria". They do however exist in the gut, and are an integral part of the process which transfer nutrients from contains of the gut into bloodstream.

    84. Re:Okay, so... by Luckyo · · Score: 1

      Because you cause multi-billion and lethal fuck ups by doing so.

    85. Re:Okay, so... by Anonymous Coward · · Score: 0

      If he doesn't even chew then that may well have a dramatic effect on the efficiency of gut bacteria in extracting nutrients.

    86. Re:Okay, so... by Anonymous Coward · · Score: 0

      Technically it would not be to bestow traits like yours, but rather like the bacteria that are in your gut, determining these things for you. A small, but important distinction lest you start believing you are your bacteria, and going all "Fly" on us or something.

    87. Re:Okay, so... by angel'o'sphere · · Score: 1

      You wrote: the bacteria create and transfer 'energy' to the body.
      Which they don't do. Now you write 'nutritions', which is better :)

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    88. Re:Okay, so... by angel'o'sphere · · Score: 1

      No it has not.
      I would suggest you care to look on the label of milk box. But yes, with all the back and forward calculations from gallons/pints to ounces etc. it is hard to figure how much 'sugar' milk actually has.
      But I relieve you, it is about 5% of its weight. If you call that 'much' then you have a strange definition of much.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    89. Re:Okay, so... by Luckyo · · Score: 1

      Question: What do we call the material form that is absorbable energy for our metabolism in the food?

      Relevant: http://lmgtfy.com/?q=synonym

    90. Re:Okay, so... by stealth_finger · · Score: 1

      The whole point is many skinny people violate this law but do not get obese.

      I do and the way I eat absolutely upsets a few larger people I know.

      burgers, doughnuts, eating out a lot, snacking all the time, yet I'm a solid 155lbs at 5'11 with a desk job as a software developer sitting all day. Nothing I do changes my weight and I'm a very small framed athletic looking individual who takes about 2 shits a day if it matters to anyone.

      I also drink loads of coffee and soda, then sit around idle and program.

      So the law is kinda bullshit for some of us.... This whole bacteria talk is about trying to bestow traits like mine unto people who can't lose weight without literally starving it out of them with your "law".

      Same here. I eat one good meal a day and drink practically nothing but tea white two. I don't think my body shape has changed since I was 18. I'm 31 now and do wonder if I'm just going to wake up at 40 with an extra 8 inches on the waist.

      --
      Wanna buy a shirt?
      https://www.redbubble.com/people/stealthfinger/shop?asc=u
    91. Re: Okay, so... by Anonymous Coward · · Score: 0

      geez if thats the case i suppose i intake 5000-6000 calories a day and i am 148Lbs at 6 foot tall i'm 24 and i have been doing this for like 8 years

      my day consists of fast food twice a day plus two or three other meals and atleast two sometimes four cans of NOS the energy drink and arizona iced tee or some kind of cheap sugar filled juice plus candy,PB&J sandwiches,cereal,pop tarts,cheap snack cheese crackers,beef jerky,bear claws and then i eat dinner but i am awake generally 18 hours a day sitting on my ass here at the computer and i couldnt gain a pound if i tried

      in fact i have been slowly losing weight... anybody want my poop?

    92. Re:Okay, so... by AK+Marc · · Score: 1

      So between "taking in", "putting out", and "storing" everything eventually adds up to 0.

      So you said nothing useful, in a pompous and pretentious manner. Go it. Everyone should have ignored your meaningless comment.

    93. Re:Okay, so... by AK+Marc · · Score: 1

      The problem is that "physics" doesn't define the definition of "calorie" in this context. You are wrong, and using the wrong terminology. The reason so many people are arguing with you isn't that they don't understand what you said, but that what you said is simply wrong. And you are going back to explain how what you said isn't what you meant, without realizing you were wrong in the first place.

    94. Re:Okay, so... by AK+Marc · · Score: 1
      You wrote:

      To get fat from energy, you need said energy to be absorbed form your gut into your bloodstream. Your idea how digesting works is wrong.

      Bacterias don't 'transfer energy' to the body. They simply split stuff up and the body takes the waste/remains of that splitting.

      We'll ignore the incorrect formatting for the quote, but note the words quoted. Nowhere does the word "bacteria" appear in the quote.

      Also, you put "transfer energy" in quotes. This should imply that it is somewhere quoted, especially when you are nit picking. It isn't.

      Your reply is a non sequitur. He didn't say what you assert he said.

      You are wrong. He is right. Give it up.

    95. Re:Okay, so... by AK+Marc · · Score: 1

      And by what measure do you measure your calories out? Standard nutrition says "calories eaten vs calories burned" because there's no measurement of calories "removed". Physics may work, but is not applicable to the practical application of diet. Nobody is saying that physics is wrong. just that it's useless in this particular applied category.

  3. Re:what about skinny people? by flyneye · · Score: 0

    How about a physically fit persons shit? I can donate a corn/jalapeno rich stool to any underweight or obese testers, hungry for a tasty change. I've been told it smells a bit like roses too.

    --
    *Repent!Quit Your Job!Slack Off!The World Ends Tomorrow and You May Die!
  4. Choose your food handlers wisely by NotQuiteReal · · Score: 5, Funny

    Only eat at places run by skinny people.

    --
    This issue is a bit more complicated than you think.
    1. Re:Choose your food handlers wisely by MTEK · · Score: 3, Funny

      And only those who could give a shit.

  5. Have I lost my mind? by kencurry · · Score: 2

    What in the name of god is a fecal transplant?

    --
    sigs are for losers (except to point out that sigs are for losers)
    1. Re:Have I lost my mind? by Shados · · Score: 5, Informative

      When something happens and your guts flora goes out of wack, because of a previous illness, some surgery, whatever, your digestive system suffers quite a bit, and has no way to recover (those bacterias don't come out of nowhere...if 100% of them are gone, they're not coming back...).

      So the only way to get them back is to transplant bacterias from someone else, to "bootstrap" your system anew. And the easiest way to get a bunch of those bacterias is in, well...yanno...

      So they either take a piece and stick it in you, or they make a pill out of a little bit of it. Gross as hell, but less gross than dealing with a fucked up guts flora.

    2. Re:Have I lost my mind? by itzly · · Score: 1

      Moving beneficial intestinal bacteria from one person to another.

    3. Re:Have I lost my mind? by demonlapin · · Score: 1

      It's just what it sounds like. You take poop from one person and inject it into another person's colon. The goal is to transfer useful microbes. For obvious reasons, they generally try to use family members or spouses.

    4. Re:Have I lost my mind? by SuricouRaven · · Score: 4, Interesting

      Exactly what it sounds like.

      Humans have gut bacteria. These bacteria are required for the gut to function properly. In some cases a person can lose theirs following a course of really powerful antibiotics - they'll kill whatever's causing their disease, but kill all the required bacteria in their gut too. This is a bad thing: Gut without bacteria doesn't work very well and, though it's not fatal, is going to leave the patient suffering a number of unpleasant conditions. The solution is very simple though. Just take someone with a healthy bacterial ecosystem in their gut, extract a handy lump of bacteria, insert it into the unhealthy patient. The ready-made bacterial colony then takes hold there and returns things to a healthy balance. It sounds disgusting and, well, it is. But it works.

    5. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      Huh? What's the obvious reason?

    6. Re:Have I lost my mind? by ColdWetDog · · Score: 5, Informative

      It doesn't have to be all that bad. You freeze dry the feces (that can't be fun). The smelly parts go up the evaporator, mostly. Some protocols spin out the debris (yesterdays burrito bits) leaving you with some flotsam that should be mostly bacteria. You put that in an enteric coated pill (so the stomach acid doesn't clobber everything) or you shove it up the butt using one of a number of techniques (insert, so to speak, favorite joke here).

      Wait a bit and see what happens.

      This is a very trendy field since 1) it clearly works for a defined illness (Clostridium difficele infections) 2) has an interesting and biologically plausible mechanism(s) 3) is easy to make (see above, do not try this at home, professional driver on closed course and all that) and has virtually limitless advertising possibilities. Even aside from the Holy Grail of weight loss and 4) should be able to keep Jon Stewart, 4chan and the rest of the planet in bad jokes for quite some time.

      --
      Faster! Faster! Faster would be better!
    7. Re:Have I lost my mind? by Applehu+Akbar · · Score: 1

      Does it have to be branded "FecaMax" at $10,000 per gram, or is there a generic?

    8. Re:Have I lost my mind? by trout007 · · Score: 2

      That's not quite accurate. Those bacteria are all around us and especially on the food you eat. It may take a while for those bacteria to increase enough in population so to speed things up you inoculate your system.

      The same thing can happen with bread,beer or wine. You can go ahead and wait for the natural yeast to take over or you can take a vial of ready to go yeast and pitch it in to get things started right away.

      I know this personally because when I met my wife her family ate beans quite often. I was very gassy for a couple of months until the bacteria that digested the beans got to the point they could digest it all.

      --
      I love Jesus, except for his foreign policy.
    9. Re:Have I lost my mind? by drinkypoo · · Score: 2

      The same thing can happen with bread,beer or wine. You can go ahead and wait for the natural yeast to take over or you can take a vial of ready to go yeast and pitch it in to get things started right away.

      The same thing that can happen with bread, beer, or wine can happen in your body, too: the wrong (undesirable) flora take root before the stuff that you want, and it outcompetes the desirable organisms and then you suffer. Or in the case of beer, you get nasty beer. It may still be alcoholic, but it will probably be gross.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    10. Re:Have I lost my mind? by Anonymous Coward · · Score: 1

      When something happens and your guts flora goes out of wack

      There is only one way gut bacteria go out of whack where it can't recover - antibiotics. More specifically, oral antibiotics.

      Antibiotics are a very big selection factor in the gut. They skew the entire system towards resistant strains. And yes, there are gut bacteria that are basically immune to all forms of antibiotics and there are some that are killed off completely with 1 pill and most are in the middle somewhere.

      Ask yourself - why is C. Diff. infections predominantly secondary infections in hospitals when someone is taking antibiotics to prevent infections? C. Diff. is everywhere in the world but it never colonizes your gut until it gets help from antibiotics.

      And since gut bacteria are majority of the cells in your body, and since they produce literally tons of chemicals in your lifetime, these things will affect your life. Everything. From your personality to how long you'll live (eating red meat has a chemical in the meat that feeds some bad bacteria that produce protein that then causes inflation in your cardio system and you get blocked arteries) to autism. And no, I'm not making any of these up - look at connection between antibiotic usage to treat childhood "infections" like "stubborn ear infection" (which is 90+% viral), antibiotic types and then onset of autism. Suddenly population without antibiotics and NO autism, moves to a nation with antibiotics and that results in largest autism population in any subgroup.

      http://www.autismdailynewscast...

      This is not just Minnesota. (Gut bacteria connection is not my connection - much smarter people came up with it over 10 years ago - look in real, peer reviewed journals for that)

      And then I'll throw this out there. Remember the stories of alien abductions and rectal probing? Now that I know more about gut flora, I can't laugh at this anymore. If Earth was a lab experiment, the symbiotic relationships like gut flora are probably the most complex parts of ecology. *We* ignored them for generations. Even today, we view this as some sort of unclean science.

      To sum this up, we have a rainforest in our guts. It's self-balancing. It feeds us and determines many parts of our lives. But then we use oral antibiotics, instead of much more targeted injectables, and that is like using nukes on that rainforest because there could be some wrong species of fish in a jungle river....

    11. Re:Have I lost my mind? by Opportunist · · Score: 1

      You eat the poopoo!

      (ok, I know, not quite, but hey, when can you actually use that meme without going off topic?)

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    12. Re: Have I lost my mind? by Anonymous Coward · · Score: 0

      Stool sample is inserted with a rectal endoscope.

    13. Re:Have I lost my mind? by cdxta · · Score: 1

      Exactly what it sounds like.

      Humans have gut bacteria. These bacteria are required for the gut to function properly. In some cases a person can lose theirs following a course of really powerful antibiotics ...

      Fully agree, I’ve been health my entire life and haven’t had any heath problem and was in great health and even slightly underweight, but after going into the doctor about a year ago for what looked to be an ingrown fingernail I thought might need to be cut out, but instead my doctor just prescribed me a heavy 10 days course of antibiotics and sent me on my merry way. I never felt fully healthy or the same since ever since. It was only after the first or second day of antibiotics that I started reading about the full effects of antibiotics and once you start you’re not supposed to stop... In hindsight, my finger was healing on its own slowly and I probably should have never taken those antibiotics the doctor prescribed because it “looked like it might be infected”.

      I’m not going back to a doctor again unless I’m on my death bed which will probably be much sooner now after those poison pills. I’m really starting to distrust the medical industry; half the commercials on TV now are for pills or hospitals. Why do hospitals and health offices need to advertise? It feels like the health system is becoming the new car dealerships and service garages for your health and is just trying to make a quick big buck on the lack of transparency and informed choices you can make.

    14. Re:Have I lost my mind? by TubeSteak · · Score: 2

      3) is easy to make (see above, do not try this at home, professional driver on closed course and all that)

      Actually, people are doing it at home.

      It's a SFW thing to search for, as long as you get your search terms right.
      "diy" or "home" and "fecal transplant"

      There's really no difference between what you can do at home and what a doctor can do for you, other than ordering up disease and parasite screening tests for your donor.

      --
      [Fuck Beta]
      o0t!
    15. Re:Have I lost my mind? by BarbaraHudson · · Score: 1

      "should be able to keep Jon Stewart, 4chan and the rest of the planet in bad jokes for quite some time."

      No sh*t, Sherlock!

      (Sorry, it's a sh*tty joke, but someone had to say it :-)

      I remember how weird it was when I was visiting someone in the hospital and saw the sign on the door saying the room was for fecal transplants. Must be a real sh*tty job working there ... especially as the janitor.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    16. Re:Have I lost my mind? by BarbaraHudson · · Score: 1

      half the commercials on TV now are for pills or hospitals. Why do hospitals and health offices need to advertise?

      Because you're in the US. Used to never see it in Canada except for OTC (over the counter) "medicines." Recently a few have crept in. They can't be too effective, because they really haven't flourished.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    17. Re:Have I lost my mind? by dotancohen · · Score: 2

      ...your digestive system suffers quite a bit, and has no way to recover (those bacterias don't come out of nowhere...if 100% of them are gone, they're not coming back...

      Where do babies get them from? Surely there is no interintestinal transfer from mom to womb.

      --
      It is dangerous to be right when the government is wrong.
    18. Re:Have I lost my mind? by wisnoskij · · Score: 1

      "has no way to recover" Well there is the Appendix, but nothing is foolproof.

      --
      Troll is not a replacement for I disagree.
    19. Re:Have I lost my mind? by Chris+Mattern · · Score: 5, Interesting

      Where do babies get them from? Surely there is no interintestinal transfer from mom to womb.

      The child's intestine gets colonized during childbirth. That's been discovered to be one of the problems with Caesarian section, in fact. The baby's large intestine doesn't get the proper bacterial colonization.

    20. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      Or you could just get a new doctor. Your sample size apparently being "one" might, y'know, throw off your conclusions a bit.

    21. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      Yes, there is a generic. Look up the brand Two Girls, One Cup. You can get it on the cheap that way.

    22. Re:Have I lost my mind? by BarbaraHudson · · Score: 1

      ...your digestive system suffers quite a bit, and has no way to recover (those bacterias don't come out of nowhere...if 100% of them are gone, they're not coming back...

      Where do babies get them from? Surely there is no interintestinal transfer from mom to womb.

      If you've ever changed an infant's diaper you'd have seen that green-yellow mess that comes out for a while.

      Kids put everything in their mouth. Put them on the floor, they'll lick the carpets. Unsupervised they'll eat the "poopsicles" in the cat litter, and play with the dogs "turdles." Every time they find something they'll put it in their mouth.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    23. Re:Have I lost my mind? by ShanghaiBill · · Score: 1

      Recently a few have crept in. They can't be too effective, because they really haven't flourished.

      The Canadian government negotiates bulk prices directly with the pharmaceutical companies, which reduces their profit margins. So an ad for a prescription drug, that will increase sales by, say 20%, is worth running in America, but will not pay for itself in Canada. In America, the pharmaceutical companies are incentivized to charge higher prices in order to pay for more marketing. The ads will increase sales more than lower prices will.

    24. Re:Have I lost my mind? by sonicmerlin · · Score: 1

      From med school: they swallow the mother's fluids during childbirth.

    25. Re:Have I lost my mind? by gmuslera · · Score: 1

      God have nothing to do with that. More than a single entity we are a community, not just formed by our own cells and ADN, but also by several bacterial ecosystems that we have in different places of our bodies. We get the first load right in the birth canal, then though our mothers milk, and from there influenced by our own environment, food, etc.

      One of the mainly studied ones are the gut bacteria, that do things like processing the food that we can't, or influences our mood and other cognitive processes. But them could be affected by excess of antibiotics, diseases, diarrhea and other causes, and having a negative health effect. We have a backup for that flora in the appendix (if you think it was worthless, and worthy taking it out just in case, it is pretty useful), but it may not be enough. A fecal transplant is the transplant of the gut bacteria of a healthy person to fix that ecosystem, and if you can figure out, the easiest way to get it is from feces

    26. Re:Have I lost my mind? by itzly · · Score: 1

      And how does the mom's gut flora end up in the fluids ?

    27. Re:Have I lost my mind? by dotancohen · · Score: 1

      Thank you, that is rather more interesting than I expected.

      --
      It is dangerous to be right when the government is wrong.
    28. Re:Have I lost my mind? by dotancohen · · Score: 1

      If you've ever changed an infant's diaper you'd have seen that green-yellow mess that comes out for a while.

      Kids put everything in their mouth. Put them on the floor, they'll lick the carpets. Unsupervised they'll eat the "poopsicles" in the cat litter, and play with the dogs "turdles." Every time they find something they'll put it in their mouth.

      Thanks. In fact, I have changed quite a few diapers and I'd love to change more!

      --
      It is dangerous to be right when the government is wrong.
    29. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      after going into the doctor about a year ago for what looked to be an ingrown fingernail I thought might need to be cut out, but instead my doctor just prescribed me a heavy 10 days course of antibiotics and sent me on my merry way. I never felt fully healthy or the same since ever since.

      Because I have mitral valve prolapse I often have to take a course of antibiotics just to go to the dentist.
      I've found that eating a couple of yogurts every day while taking the antibiotics keeps my stomach happy.

    30. Re:Have I lost my mind? by Strider- · · Score: 1

      The Canadian government negotiates bulk prices directly with the pharmaceutical companies, which reduces their profit margins. So an ad for a prescription drug, that will increase sales by, say 20%, is worth running in America, but will not pay for itself in Canada.

      Also, in Canada, it's against the law to advertise the condition and the prescription medication to treat it in the same advertisement. This is why you see some really cheeky Viagra and Cialis advertisements, but they don't say what it treats, and Erectile Dysfunction advertisements that say "Talk to your doctor."

      --
      ...si hoc legere nimium eruditionis habes...
    31. Re:Have I lost my mind? by jader3rd · · Score: 1

      What in the name of god is a fecal transplant?

      It's an operation where fecal matter is transplanted from a donor to a patient.
      You know, there are web search engines these days that can be used to answer questions for you. You don't need to wave your ignorance around with pride anymore.

    32. Re:Have I lost my mind? by Luckyo · · Score: 1

      IIRC pre-birth vagina's PH changes to allow bacterial migration from anal opening. As baby is born, it literally licks up the vaginal walls. In caesarean section birth doctors now take vaginal swabs and put them in baby's mouth to produce the same result.
      Follow-up comes through child having an instinct to put things in their mouths and mother's milk.

      Remind yourself that women commonly suffer urinary tract infections for that same reason - something that men almost never suffer from in comparison.

    33. Re:Have I lost my mind? by ceoyoyo · · Score: 3, Interesting

      This is what I tell my colleagues, who notice that I never really get sick. If you didn't grow up in the country eating dirt, head out to a mall and find an escalator. Put your tongue on the railing and wait for it to go all the way around. If you don't die, you'll find yourself with a nice healthy immune system and excellent gut flora.

      So far nobody has taken me up on it.

    34. Re:Have I lost my mind? by angel'o'sphere · · Score: 1

      The children get it from father and mother who 'pre chew' the first solid food for them.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    35. Re:Have I lost my mind? by angel'o'sphere · · Score: 1

      Children get colonized during child birth, but that does not really cover the intestine.

      Cesarians indeed my lead to later problems regarding 'standard bacteria' in/on human bodies.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    36. Re:Have I lost my mind? by Anonymous Coward · · Score: 2, Interesting

      You've clearly never been at the birth of a child* :)

      We have a five month old and the birth is still a surprisingly vivid memory for me. The one thing child birth is not, is clean. There is rather a lot of everything, everywhere.

      There is a lot of transfer of bodily substances of all types during a normal birth, including bacteria from the mum's gut. It's a known issue for babies born by c-section who don't get closely acquainted with their mother's backside. From what I've been told in anti-natal classes even back-to-back babies (those who come out head first but facing the front, ideal is rear facing) get a reduced exposure.

      It takes several days for a babies digestive system to kick into gear, during which time those bacteria are colonising the gut, skin and everything else on the body. C-section babies still get those bacteria from skin to skin transfer, but it takes longer to build up and they may not get the full set.

      * Other than your own of course...

    37. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      wouldn't freeze-drying kill the bacteria?

    38. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      There are various life-saving procedures that require all the bacteria in a persons gut to be killed. (I think Crones disease and Colitis might be one). Without bacteria in your gut, you really can't absorb food or nutrients (at least not very well). You can only eat a very small selection of foods, and they don't provide all the nutrients you need, and you wind up being very weak). In order to restore the gut bacteria, they (initially) took feces (poop_ from another person, got someone desperate enough to try anything, made sure it didn't have anything really dangerous in it (no diseases) and then swallow it. The process was (awful), but effective. After 3 days of gargling and brushing their teeth and getting over it, they were once again healthy (able to eat foods, gaining weight, stronger, etc.) Now instead of raw poop, they take the feces, test for harmful disease and if ok remove water and odour, take a small sample of the bacteria, compress it into a pill form, coat it with wax and give that to people. The findings about weight would lead to a conclusion that diet and exercise might not be the reason for obesity, it might have more to do with the bacteria in your gut. There are other studies that the lack of certain bacteria in your gut can give symptoms of Autism (and preliminary studies have -completely- reversed the symptoms in some patients). Jenny McCarthy and vaccines bedamned.

    39. Re:Have I lost my mind? by dotancohen · · Score: 1

      I doubt that gut flora is transmitted through breast milk.

      --
      It is dangerous to be right when the government is wrong.
    40. Re:Have I lost my mind? by Anonymous Coward · · Score: 0

      Please cite sources for the premises presented. Particularly interested in the work on C-section and intestinal bacteria.

    41. Re:Have I lost my mind? by angel'o'sphere · · Score: 1

      It is not, how do you think so?

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    42. Re:Have I lost my mind? by RyoShin · · Score: 1

      If you can truly gain good gut flora from simply licking things (the idea sounds sketchy, but I don't know that it's impossible), then I would think there would be companies are paid by people simply to shuttle them around to where very fit people work (supermodel studios, sport start locker rooms) immediately after the fit people are done working and have them lick any and everything they can.

      (Someone follows behind and gives the place a good cleaning to make sure a supermodel can't get the fat bacteria when she licks something.)

    43. Re:Have I lost my mind? by ceoyoyo · · Score: 1

      It's not impossible. Lots of people don't wash their hands very well.

      There are studies, including very large ones, that show the more variety of microbes you're exposed to early in life, the less likely you are to suffer from autoimmune disorders. You may or may not be able to get some benefits in adulthood.

      In the gut, it probably isn't a matter of having this or that bacteria, but rather having a variety, possibly a very large variety, in the correct proportions. It's possible that you could beneficially supplement your gut microbes by importing them from the environment, like children do. It's probably not a matter of eating skinny people microbes and not fat people ones, but rather having enough diversity.

  6. Re:what about skinny people? by Anonymous Coward · · Score: 1

    Yes.

    After every meal, eat a skinny person's shit, and thereby retch up the food you've just eaten.

  7. Story Draws Trolls to Convene by flyneye · · Score: 1

    So, don't take any shit...

    --
    *Repent!Quit Your Job!Slack Off!The World Ends Tomorrow and You May Die!
  8. This is why by jtownatpunk.net · · Score: 0

    This is why you never go ass to mouth.

    1. Re:This is why by Anonymous Coward · · Score: 0

      ASS TO ASS

  9. Maybe just not being ill by cpuffer_hammer · · Score: 2

    Being ill takes a lot of energy, being healthy again but still eating and exorsizing to the same level could result weight gain.
    I would think a search though the data should start to answer this question. Or relationship with our gutflora is more complex than can be summed up. There may be lots of changes in peoples that could be made this way. More collecting of before and after facts (even things like concentration, strangth, dexterity) should be considered.

    1. Re:Maybe just not being ill by Anonymous Coward · · Score: 0

      Yeah, I'm not buying it either. If you watch "My 600 lb Life" on Discovery, you'll see many people who claim their weight is due to all sorts of other medical things, but in the end you see footage of them sneaking McDonalds all the time (yes, it is nearly always McDonalds). The only way this bacteria can make people fat is if it increases cravings for fast food.

      My guess is she was sedentary the entire time she was in hospital, and the healthy bacteria have allowed her to eat normally or aggressively again. The end result is a low metabolism with a fully digesting system. You can't get fat without calories.

      Another possibility is that the pain meds she was taking in hospital have triggered an addictive cycle and she is using food to cover her loss of the pain meds.

    2. Re:Maybe just not being ill by Anonymous Coward · · Score: 3, Insightful

      If you watch "My 600 lb Life" on Discovery...

      ...then you will see exactly what the producers of "My 600 lb Life" want you to see, which is a tiny sliver of the truth that has been carefully selected, edited, and re-contextualized to tell you what they know you want to hear.

      Reality TV - isn't.

  10. That totally explains why I'm fat by Anonymous Coward · · Score: 1

    I was born with bad genes.

    I will try anything to lose weight, except do exercise or cut down on food. If there's a new surgery to replace my fat generating parts, sign me up!

    1. Re:That totally explains why I'm fat by ColdWetDog · · Score: 1

      Roll up your sleeves and bend over.

      --
      Faster! Faster! Faster would be better!
  11. Re:what about skinny people? by fustakrakich · · Score: 5, Interesting

    Now you have me wondering if we can make dumb people smart, and mean people nice. We may achieve world peace through fecal transplants.

    --
    “He’s not deformed, he’s just drunk!”
  12. ))(( back and forth forever by Anonymous Coward · · Score: 0

    You poop into my butt hole and I poop into your butt hole...
    back and forth...
    forever.

  13. Intestinal infection, don't jump to conclusions. by Anonymous Coward · · Score: 2, Insightful

    She wasn't overweight when she had a persistent intestinal infection and gained weight after it was cured. She might well be eating more simply because it doesn't cause her discomfort anymore, or her body uses fewer resources because it doesn't have to fight an infection, or her colon has become better at absorbing the nutrients in her food because it's no longer infected.

    Worth looking into, but if your conclusion is that the bacterial composition in the colon makes people fat, you're getting ahead of yourself.

  14. Re:what about skinny people? by Shados · · Score: 4, Interesting

    I know its a joke, but not really. At the end of the day, humans are just fairly complicated machines, or even just a big complex chemical reaction.

    Pretty much everything we do comes from either training/uprising, or from some biological system or another. As time goes, we'll figure out all of the later...and statistics will take care of the former.

    Will be a very boring world probably, but...

  15. Causation of other things? by Anonymous Coward · · Score: 0

    Huh. I wonder if a whole host of problems people have after major medical events can be attributed to a change in gut fauna triggered by antibiotics. My body has just been different after my emergency appendectomy.

    1. Re:Causation of other things? by ColdWetDog · · Score: 1

      Huh. I wonder if a whole host of problems people have after major medical events can be attributed to a change in gut fauna triggered by antibiotics. My body has just been different after my emergency appendectomy.

      Are you sure it was an appendectomy?

      --
      Faster! Faster! Faster would be better!
    2. Re:Causation of other things? by sir-gold · · Score: 1, Interesting

      There have been studies showing a link between heavy antibiotic use in children under the age of 3 and regressive autism, caused by a commonly occurring antibacterial-resistant bacteria (Clostridia) proliferating in the absence of competition, which produces a neurotoxin as a waste byproduct (Propionic Acid)

      This is why I find the anti-vaxxers so ironic. They ALMOST figured it out, but started blaming vaccines instead of antibiotics.

    3. Re:Causation of other things? by 50000BTU_barbecue · · Score: 2

      Yup, same here. After my wisdom tooth removal, I was prescribed Dalacin. I got a nice case of pseudomembranous colitis which sent me to the ER, with acute pain like being stabbed in the gut.

      After being fixed with several IV courses of penicillin, I was "cured", but since then I have many IBS-type symptoms and have had to make a list of items I must avoid eating.

      I'm fatter and depressed now.

      --
      Mostly random stuff.
    4. Re:Causation of other things? by ColdWetDog · · Score: 2, Insightful

      You do realize that there 'have been studies' that show a link from pretty much anything to anything else. These sorts of studies are quick, easy and quite often, completely wrong when attempts are made to determine causality. They're like bible quotations. They can say anything you want them to say.

      Statistics is hard.

      --
      Faster! Faster! Faster would be better!
    5. Re:Causation of other things? by BarbaraHudson · · Score: 1

      You can always try yogourt. May give you the runs for a while until your body gets the bacterial mix right.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    6. Re:Causation of other things? by RightwingNutjob · · Score: 1

      Could be. Yet another reason giving out antibiotics like candy can cause more harm than good.

    7. Re:Causation of other things? by dryeo · · Score: 1

      Actually the first theories linking the MMR vaccine and autism were that the combination of 3 live viruses over whelmed some immune systems and caused changes in the guts flora which led to autism, the simple idea was that the MMR vaccine should be split into separate vaccines and staggered so as not to overwhelm some immune systems.
      Then the nutcases moved in with their mercury bullshit (most of us have mercury fillings right in our mouth)

      --
      https://en.wikipedia.org/wiki/Inverted_totalitarianism
    8. Re:Causation of other things? by sir-gold · · Score: 1

      You are right, studies can mean whatever you want them to mean, but that doesn't mean this idea isn't on the right path at least.

      The basis is 2 main ideas that don't have anything to do with studies, and that really aren't in any dispute:

      1. The human mind is drastically affected by the mix of chemicals inside the body
      2. Permanently changing the balance of the majority of the bacteria in the body (and thus the balance of waste byproducts), will change the mix of chemicals inside the body.

      It doesn't really matter WHAT causes the bacteria mix to change, but we now know that messing with it can have some serious long-term side effects, and some of those side effects could explain very common "epidemics" such as obesity, autism, food allergies, and the impending zombie apocalypse.

    9. Re:Causation of other things? by Anonymous Coward · · Score: 0

      Yup, same here. After my wisdom tooth removal, I was prescribed Dalacin. I got a nice case of pseudomembranous colitis which sent me to the ER, with acute pain like being stabbed in the gut.

      After being fixed with several IV courses of penicillin, I was "cured", but since then I have many IBS-type symptoms and have had to make a list of items I must avoid eating.

      Actually, I was having more IBS symptoms until I ate at an Indian restaurant near San Diego where I suspect poor hygiene on the part of one of the servers. Anyway, I got the runs immediately, and improved bowel health shorthly thereafter. So, you could try going to bad Indian restaurants to get an inadvertent fecal transplant that way.

    10. Re:Causation of other things? by ceoyoyo · · Score: 1

      Statistics is probabilistic. Even when you do it right, your conclusion is more than likely going to be wrong.

      "Studies" are what grew out of scientists writing letters to each other saying "hey Joe, look what I found. Interesting hey? You should try it!" They're not meant to be conclusive by themselves, but rather indications of what experiments are interesting to replicate and expand.

    11. Re:Causation of other things? by ceoyoyo · · Score: 1

      Conveniently, the medical doctor who advanced those "theories" and unethically experimented on children to "prove" them, had a financial interest in just such a split up vaccine.

    12. Re:Causation of other things? by Anonymous Coward · · Score: 0

      Are you going to shit in his yoghurt, to provide the bacterial cultures important to the human gut, or do live yoghurts seriously contain everything necessary to repopulate the gut? Would kefir or tibicos be better, worse, good in addition?

  16. Re: what about skinny people? by Anonymous Coward · · Score: 0

    Salad tossin; it's how you lose weight!

  17. n=1? by asjk · · Score: 1

    no text

  18. But, but, but ... by Anonymous Coward · · Score: 0

    I thought they were all lazy bastards, if they eat more calories then they burn in a day that's how weight gain occurs. How is this possible my world is crumbling! How will I make fun of all dwarf planets orbiting the aisles of my local Walmart if it's not really their fault?

  19. Re:Or the most obvious explaination by Anonymous Coward · · Score: 1

    dude the summary...

    After the procedure, despite a medically supervised liquid protein diet and exercise regimen, the woman remained obese

  20. Cordyceps controls bug brains to propagate... by Pezbian · · Score: 4, Interesting

    More evidence to support my hypothesis that gut flora plays games with us. All it takes is one bacteria secreting a chemical that makes us feel like crap if we don't eat the sugars or whatever it craves and secreting something else that makes us feel good when we do.

    Maybe resisting that sick feeling and staying on course means the rogue organism will starve to death?

    There are gut flora organisms which can't be cultured outside the gut, or even outside certain portions of the gut. We don't know what a lot of them do, but there are something like 2kg (~4lb) of them in each of us. Being quite small, each of us is vastly outnumbered on the scale that war against these beasts is basically genocide (How To Make A Vegan Explode -101).

    --
    In a world of the blind, the one-eyed man is king--and the two-eyed man is a heretic.
    1. Re:Cordyceps controls bug brains to propagate... by dAzED1 · · Score: 1

      uh, why would a vegan "explode" over concerns about bacteria? It's so funny to hear people say vegans bring up veganism...when really it's just idiots that insert vegan-bashing into unrelated conversations, and the vegans just end up saying "uh, what?" Plants are exponentially more complex, and vegans eat the heck out of those....

    2. Re:Cordyceps controls bug brains to propagate... by Anonymous Coward · · Score: 0

      You sound mad, bra. If you'd like to calm down and help that angry hair-trigger you got, I'd suggest bacon. Bacon makes everyone happy- even vogons.

  21. Re:what about skinny people? by Applehu+Akbar · · Score: 4, Funny

    So that's the definition of 'humanitarian.' I always wondered about that.

  22. Re:what about skinny people? by stephanruby · · Score: 4, Informative

    If a fat person eats skinny people shit will they lose weight??

    I don't know about that one, but having worms in your intestine can make you lose weight for sure.

    See picture. It's just like a big bowl of yummy pasta!

  23. Doubtful by Anonymous Coward · · Score: 3, Insightful

    The presence of gut bacteria with such high efficiency (they ones that make you fat by being too good at their job) won't be counter-acted by the presence of the less efficient variety.

    What this means, though, is that I can no longer feel the familiar sense of derision for fat people. Their obesity really may be a product of their microecology, rather than their laziness and hedonistic eating habits. Now I have to feel pity for them instead.

    I guess I can still feel superior to them, since I still am physically fit compared to them...I just can't feel like this was the result of superior decisions any more.

    Oh well, there are plenty of other ways to save my fragile ego.

    1. Re:Doubtful by Hadlock · · Score: 1, Flamebait

      You still need to consume > 2200-2700 calories a day for an average size human to gain weight beyond 200 lbs or so (realistically you'll top out at about 180lbs even if you sleep all day but let's use round numbers). If you're 250 lbs or 300 lbs you have to consume way more than 3000 calories a day to simply maintain that bulk of flesh. Fat people are still fat because they eat more than they ought to, this article, if 100% true, doesn't change that fact

      --
      moox. for a new generation.
    2. Re:Doubtful by sonicmerlin · · Score: 4, Informative

      Did you even bother to read the article? The woman's eating habits and calorie intake were carefully measured and she gained weight despite not changing anything. I've lost 35 lbs with exercise, but despite spending almost 100 minutes and 1100 calories a day, I still can't get rid of the last 5-10 lbs of flab. It doesn't matter how little I eat.

    3. Re:Doubtful by Hadlock · · Score: 1

      You can't eat 2000 calories a day and sustain 3000 calories worth of warm-blooded flesh, either the study is in error or the laws of thermodynamics needs to be re-examined. Unless the bacteria use some sort of endothermic process and the room she was kept in stayed above 98.6F in which case I want to read the article.

      --
      moox. for a new generation.
    4. Re: Doubtful by Anonymous Coward · · Score: 0

      We only have the womans own words that she followed the diet since there was no intervention.

    5. Re:Doubtful by Cinnamon+Beige · · Score: 4, Informative

      That only applies when you're dealing with basically an ISO Standard nutrient processing system on a lab-made nutrient slurry--basically, lab mice on lab block.

      Basically, gut bacteria are actually a pretty essential part of processing nutrients, and in some cases the actual source of much of them. Certain types of problems basically will leave you incapable of properly processing parts--for example, with my aunt certain kinds of foods are now pretty much processed directly into fats, and the body is quite capable of taking part of those 3000 Calories' worth of warm-blooded flesh and using that to sustain it when the 2000 Calories of the food intake is being mostly stored. (And yes, the capitalization matters: nutrition uses the kilocalorie, actually, and in a confusing fit of non-standard metric renders it Calorie instead. Either way, the amount of error due to rounding introduced into the values is left as an exercise for the reader.)

      This can, however, be caused by things like a food intolerance or a metabolic dysfunction, and one of the basic tests to see if the person's obesity is a symptom is to, well, cut the caloric intake while maintaining the same levels of activity and see if weight loss happens. The wide range of things it's a symptom of--from things as amazingly cheap & easy to treat such as thyroid disease to those essential to catch early like cancer--are such that failing to check the cause is like...well...failing to check to see if the computer's problem is that it's not turned on.

    6. Re:Doubtful by ceoyoyo · · Score: 1

      Actually, animal experiments suggest that yes, fecal transplants from skinny people might help fat people lose weight. The digestive system is complicated, and it's not just a matter of "efficient" bacteria. In addition, the transplanted bacteria might outcompete the native versions and take over. Also, you generally don't just shove some poop up someone's ass in a fecal transplant. Usually the native flora has been killed or seriously weakened by antibiotics first.

    7. Re:Doubtful by angel'o'sphere · · Score: 1

      You don't understand the fact.

      A german ray bread, 100 grams, has about 300kcal. That is mainly for the "carbs" (48g), it contains ofc also proteins and fat.

      However it also contains 6g fibres. If your gut bacteria can convert those fibers into carbs, this means extra 12% kcals, which is 36 kcal if I made no mistake.

      Does not sound like much, does it? Shall we examine the healthiness of Broccoli instead? After all it contains lots of trace elements, 100g alone settle your daily Vitamin C needs by 110% etc.

      100g broccoli e.g. has only 2.5g carbs. So it makes sense to drop a bit if the rice, right? And eat 200g broccoli instead. However 100g broccoli contain also 3g fibers! If you can digest the fibers (which most obese people do) you just doubled the kcal intake by a factor bigger than two!

      Instead of roughly 35kcla/100g you are now at 75kcal.

      Luckily broccoli is low on carbs, so the effect is not that heavy.

      Nevertheless nutrition tables only hold the nutrition/kcal values for carbs, fat and proteins because the 'school knowledge' is: fibers can not be digested.

      On top of that most diets suggest to eat fiber rich, because they fill the belly and cost nothing: wrong!

      And on top of that again, the kcal tables for food already have the 'cost of digesting' subtracted. E.g. cucumber has about 15kcal per 100g. Ofc that is wrong. The true value is something like 20kcal (estimated) but your body already burns a quarter of it while digesting it. Hence the nutrition tables correct the kcal values for the amount lost by digesting (because that is different for every vegetable/fruit/kind of meat).

      However, if you have "better" gut bacteria, you need less energy and have to correct the net value of the kcal of the affected food upwards.

      So again: your silly hidden argument "obese people are fat, because they eat to much" is only correct on the bare physics of how human bodies work.

      To make them a diet that fits them, you can not go and say: you need 3500kcal a day, I look you up some meals that only contain 1800kcal and you should lose weight. Nearly every super diet meal a layman will figure will have about twice as many kcal as listed on the description.
      In my example here: 3600, versus the 3500 needed, ouch!

      Also keep in mind, your whole argumentation was based on a "bulk of flesh" ... obese people are a bulk of fat.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    8. Re:Doubtful by angel'o'sphere · · Score: 1

      Sorry, was not meant to be _bold_ at the end ... my fault of not previewing.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    9. Re:Doubtful by angel'o'sphere · · Score: 2, Informative

      Actually that has nothing to do with the laws of thermodynamics. (Hint: read them. You figure they are easy to understand and focus around heat engines, notable about the relation between volume, temperature and pressure of gases)

      Secondly, if you had read the article, which you did mot have obviously, you had noticed that the 'victim' here has the 'wrong' gut bacterias. What is 2000kcal on paper, according to nutrition tables, is 3000 - 3200kcal for her (that is not in the paper, that is my estimate) Read my other post a few pages up, which explains it in more details.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    10. Re:Doubtful by Anonymous Coward · · Score: 0

      If you're 250 lbs or 300 lbs you have to consume way more than 3000 calories a day to simply maintain that bulk of flesh.

      This still varies a lot. About ten years ago I started gaining weight and went from about 200 to 250 lbs over the course of several years. Exercise and strict calorie counting, to the point of always feeling hungry and crappy, managed to level it off, but not cause it to go down. And the exercise was to the point of me having almost no energy to do other things through out the day. I tried variations on the diet, including less carbs, more and less fats, more and less proteins, balanced, etc., and always ended up feeling hungry.

      A couple years ago I started having some breathing issues, and found out I had some chronic lung damage (I think some of it went unnoticed because I just attributed some breathing issues to allergies and tried toughing it out...). I was able to improve my breathing over a month or two, and found I had immensely more energy. Even though at the time I actually backed way off on exercise and calorie counting, I lost 5 pounds in a month or two, and had lost 15-20 pounds in a year without much exercise or harsh diet restrictions. Probably about a year after that, I got more serious about exercise again, but stopped calorie counting all together, and am down to 215 pounds and still dropping.

      I doubt my situation applies to many other people. But there are definitely situations and conditions that can greatly influence metabolism, motivation, and energy, and I think it becomes difficult to judge exactly how much effort any given person will need to control their weight. Of course no one is saying the laws of physics will be violated, and while it is easy to count to amount of calories that go into your mouth, in the end it can be rather difficult to estimate how many calories are going out in different places.

    11. Re: Doubtful by Anonymous Coward · · Score: 0

      Everyone knows fat people are compulsive liars.

      CAPTCHA: greedily

    12. Re:Doubtful by Grishnakh · · Score: 1

      The thing I don't understand is this:

      1) I'm pretty sure this link has been known about for some time. I was reading articles to this effect several years ago. So why on earth did they decide to do a FMT from an obese patient when I, a layman on Slashdot and not a medical professional in any way, already knew that there was strong evidence that gut bacteria affected obesity and there were experiments showing this in animals?

      And 2) Why are there not already treatments for obesity using FMTs from skinny people? Instead of just feeling sorry for fat people because they have crappy gut flora, and given that we already do fecal matter transplants and have even come up with simply frozen pills people can swallow instead of having a tube jammed down their throat, doesn't it logically follow that for severely obese people, this treatment is a no-brainer?

    13. Re:Doubtful by Anonymous Coward · · Score: 0

      You are also making the erroneous assumption that many make about how the human body works: that the calories burned is a dependent variable (the independent being the level of activity). This is fundamentally false. The body has many mechanisms to increase and decrease caloric expenditure independently of your activity level. For instance, let's say on a 2,000 calorie diet and a sedentary lifestyle you happen to burn 2,000 (no weight gain or loss). Then you start cranking down the caloric intake. Guess what, the body will no find ways to conserve energy, so this can happen: 1,500 calorie intake and 1,750 (or maybe lower) burn - even for the same SAME -PERCEPTUAL- activity level. This is why dieting can be so hard when -just- cranking down the calories, the body adjusts and efficiency of the system to help the burn rate match an insufficient intake. Sadly, the body doesn't often do the reverse -although it can.

    14. Re:Doubtful by Citizen+of+Earth · · Score: 1

      I still can't get rid of the last 5-10 lbs of flab. It doesn't matter how little I eat.

      I think some WWII POWs might disagree. Unless you are claiming that you body violates the universal Law of Conservation of Mass.

    15. Re:Doubtful by mrchaotica · · Score: 1

      Usually the native flora has been killed or seriously weakened by antibiotics first.

      Speaking of which, have scientists ruled out the possibility that antibiotics killing off our "correct" gut flora caused the obesity in the first place?

      --

      "[Regarding the 'cloud,'] ownership was what made America different than Russia." -- Woz

    16. Re:Doubtful by sonicmerlin · · Score: 1

      1. Animals aren't people

      2. Unknown side effects. Doesn't always work.

    17. Re:Doubtful by Grishnakh · · Score: 2

      1. People are animals.

      Transplanting fat-rat microbes into skinny rats resulted in the skinny rats turning fat. The science behind it really isn't hard to understand: different animals have different microbe cultures in their guts, which process foods differently. So what on earth would make you think that this couldn't possibly happen with people, and that it's perfectly safe to transplant fat-person microbes into a skinny person?

      2. Well it obviously did work here: the skinny person got fat thanks to the transplant from the fat person. Good job!

      Besides, people do all kinds of crazy and dangerous stuff to try to lose weight now, including a) liposuction and b) stomach stapling. Why the hell would you not try FMT instead, which seems far less invasive and risky than cutting someone open for surgery? Hmmm... which should I try first, taking some antibiotics and then swallowing a pill with someone's fecal matter to repopulate my intestines with better bacteria, or being put under general anaesthesia and having holes cut in me and a suction tube stuck in to suck the fat out? Or better yet being cut open and having my stomach modified so I can barely eat any food at all?

    18. Re:Doubtful by Anonymous Coward · · Score: 0

      It doesn't take any energy for fat to sit around making you chubby.

    19. Re:Doubtful by Type44Q · · Score: 0

      I still can't get rid of the last 5-10 lbs of flab. It doesn't matter how little I eat

      Two words: Quit wheat.

    20. Re:Doubtful by Anonymous Coward · · Score: 0

      despite spending almost 100 minutes and 1100 calories a day, I still can't get rid of the last 5-10 lbs of flab. It doesn't matter how little I eat.

      You are getting more than 1100 kcal a day then. Most likely your issue is that food labels are lies, and you are receiving more kcal than you believe.

      Here's your godwin: multiple sources indicate that the life expectancy of a worker at Auschwitz was about 4 months. Their rations were between 1300 – 1750 calories per day. I'm sure that a lot of those people were getting fat on that diet, because all these people on the internet are saying that they put on loads of weight while exercising and eating 1500 calories per day.

      Yep, we've all seen the pictures.

      Let's put this into perspective: you would be burning more than 1,100 kcal even if you were in a coma: Energy expenditure during barbiturate coma.

      If you don't believe me, feel free to search pubmed for more BMR/RMR studies. They are all in rather close agreement. I encourage you to calculate what your RMR truly is. I guarantee you that it's higher than 1,100 kcal.

      I acknowledge that there are differences in intestinal absorption rates of nutrients, but after a certain lower bound then claims like this do in fact violate thermodynamics. Do you believe a non-radioactive rock, just sitting around, could maintain a temperature above ambient without using energy? What if the rock needed to move itself around *and* stay above ambient temp?

      Okay, so now we've proven you don't have magical thinking, you need to reconcile your RMR calculations with what you believe is your daily energy intake. When you find out these are inconsistent, which will you believe has been falsified? Thermodynamics, or the amount of energy you believe you have metabolized?

    21. Re:Doubtful by Maxo-Texas · · Score: 1

      It's more than that too. If the food doesn't fully digest and races through your bowels then you will get less calories from it. If the food passes thru slowly, you'll have more chance to absorb and digest it. And on top of that (as you say), if your gut bacteria are good at helping you digest and absorb the calories (like the japanese who can digest seaweed while it just passes thru everyone else untouched) (or just getting 99% of the value of a steak instead of 93% of the value of a steak as it passes thru) then you'll gain weight.

      If you've exercised recently your muscles will burn more calories. If you exercise for a long time, your muscles will get more efficient at burning calories to produce the same output effort so the same amount of exercise won't burn the same amount of calories and it won't leave your muscles in high burn rate as long either.

      and a person who is 200 and muscle needs more calories than a person who is 200 and more fat.

      A lot of what I just said is simply supporting and backing up what you posted.

      I'm lucky. I have a stable set weight and low hunger impulses most the time.

      --
      She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
    22. Re:Doubtful by Reziac · · Score: 1

      I imagine the bowel could be stripped and repopulated, tho -- use some of the same stuff they make you drink for colonoscopies to get it as empty as possible, then load well with the 'good' bacteria before the 'bad' can significantly regrow.

      --
      ~REZ~ #43301. Who'd fake being me anyway?
    23. Re:Doubtful by ceoyoyo · · Score: 1

      That's one of the theories about why animals fed antibiotics (which is standard practice) gain weight faster. Antibiotic effects on gut bacteria haven't been ruled out as factors in obesity, they look very much like they play a role. Artificial sweeteners also change the gut microflora. And I read an interesting paper the other day on effects of some normal-diet-level preservatives on the gut biota.

  24. Re:what about skinny people? by Immerman · · Score: 4, Insightful

    Why boring? We've established that psychopaths are far more successful in modern society, so obviously the first thing anyone who wants the best for their children should do is have them engineered for psychopathy. Empathy is for the weak. Should make things *extremely* interesting...

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  25. Re:Intestinal infection, don't jump to conclusions by cheesybagel · · Score: 1

    Or it could be that the bacteria break down the nutrients that reach the intestines better so that it eases their absorption by the gut. It is well known for example that termites can only digest cellulose tanks to microbial flora.

  26. Re:Intestinal infection, don't jump to conclusions by cheesybagel · · Score: 1

    s/tanks/thanks/g

  27. Re:what about skinny people? by Shados · · Score: 1

    Point taken. I stand corrected.

  28. So in other words, the fat woman is full of shit? by JoeyRox · · Score: 1

    Couldn't resist :)

  29. Sounds like that lady is full of shit. by Anonymous Coward · · Score: 0

    kapow!

  30. Re:what about skinny people? by Virtucon · · Score: 1

    I tried that with rice cakes once. It didn't work.

    --
    Harrison's Postulate - "For every action there is an equal and opposite criticism"
  31. ... but did the treatment work?? by lkcl · · Score: 1

    the important question is did the procedure solve the intestinal problem?

  32. Re:So What are you saying now by Anonymous Coward · · Score: 0

    best. comment. ever. top lel. 10/10.

  33. Re:Or the most obvious explaination by Anonymous Coward · · Score: 1

    I laughed out loud when I read your post.

    Yes it's dumbfounding how far off someone can get when the damn cliffnotes-like-answer was posted bluntly a few sentences from the beginning. More worrying is that the individual then thought they had enough grasp to then "teach" this profound understanding to others, steering pockets of society in the wrong direction.

    hsmith if you read this, please stop teaching others what you think you understand. damn.

  34. Re:So What are you saying now by Anonymous Coward · · Score: 0

    All you fucking scientists that on one hand say that only calories count, and all fat people are in fact faggots.

    "Scientists" don't say that, dipshits on the internet say that.

  35. In the words of Cee Lo Green by newslash.formatblows · · Score: 1

    Ain't that some shit!

  36. What? by Anonymous Coward · · Score: 0

    "as a result I'm very careful with all our donors don't use obese people."

    As a result of one case? Without more proof that this was not a one off and is not related to something other than the transplant? I didnt read the article butthis is kind of how junk science comes about.

    1. Re:What? by ceoyoyo · · Score: 1

      MDs are not scientists. They make a lot of seat-of-their-pants calls. Many of them even do so in the face of good scientific evidence.

  37. Obvious by Anonymous Coward · · Score: 0

    So don't take shit from fat people

  38. Re:what about skinny people? by TheRaven64 · · Score: 4, Interesting

    We've established that psychopaths are far more successful in modern society, so obviously the first thing anyone who wants the best for their children should do is have them engineered for psychopathy. Empathy is for the weak

    No, game theory tells us that sociopaths do well in a society that is primarily composed of non-sociopaths, but do not do so well in a society where they are the majority (and that society also doesn't do well as a whole).

    --
    I am TheRaven on Soylent News
  39. actual study by phantomfive · · Score: 4, Informative

    Here's a link to the actual study.

    In brief:
    Woman weighed 136 pounds, daughter weight 140 pounds. After transplant from daughter to woman, she didn't return for 16 months (according to my reading of the article). The woman had gained up to 177 pounds, while the daughter gained up to 170 pounds.

    So this is more a case report than an study. Journals are used for communication between professionals. This doctor is saying, "hey, something weird happened.....it might be a coincidence (there is a lot wrong with this woman), but keep an eye out for anything similar."

    --
    "First they came for the slanderers and i said nothing."
    1. Re:actual study by BarbaraHudson · · Score: 1

      Why not put it to the test? Flush her gut out again, then do another transplant with fecal matter from a skinny person. She certainly is incentivized to give it another try, and it would be another data point.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    2. Re:actual study by Primate+Pete · · Score: 1

      Yeah, but you can't normally get approval for research on humans just because "let's try it!" IMHO, this is a good thing.

    3. Re:actual study by PPH · · Score: 1

      If the first procedure wasn't research, then a second one will be done because the first 'transplant' didn't take. That happens from time to time.

      --
      Have gnu, will travel.
    4. Re:actual study by Anonymous Coward · · Score: 0

      Both mother and daughter gained roughly the same weight at the same time? While eating the same food and in the same environment? The hell you say.

    5. Re:actual study by phantomfive · · Score: 1

      While eating the same food and in the same environment?

      We don't know, it's more of a case report than a study, so not all the variables were controlled, or even reported on. It doesn't say if they were eating the same food or living in the same environment.

      --
      "First they came for the slanderers and i said nothing."
    6. Re:actual study by Anonymous Coward · · Score: 0

      I would argue none of the variables were controlled. The linked page even says the patient was not seen again until 16 months after the procedure.

    7. Re:actual study by Anonymous Coward · · Score: 0

      Yeah, according to the actual study, the woman WAS overweight before the fecal transplant (BMI 26), contrary to the summary and the linked news article.

      Also interesting:

      "At the time of FMT, her daughter's weight was 140 pounds (BMI of 26.4), but it increased later to 170 pounds."

      So the mother got the transplant before the daughter was obese. Then they both increased in weight. How could the mom catch the hypothetical "obesity causing bacteria" from her non-obese daughter?

      This would be a lot more convincing if the donor and patient did not share a household (and presumably common nutritional patterns), and if the donor was already obese before the transplant.

  40. What else? by Anonymous Coward · · Score: 0

    Which other diseases can you have with an unfortunate fecal transplant? Parkinson's, diabetes, cancer, or Crohn's disease? Parkinson's disease can apparently be seen from the intestinal track 20 years before the symptoms come apparent.

  41. Re:So What are you saying now by BarbaraHudson · · Score: 1

    BUT YOU Decide that maybe it is a good idea to shove some sterilized shit into someone gut

    The whole point of the exercise is that it's unsterilized.

    Also, only the gullible believe in "colon cleansings". You could get the same effect a lot cheaper by taking 2 bottles of Fleet, and you'll be clean as a whistle inside, but it won't improve your health.

    --
    "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
  42. Re:what about skinny people? by ShanghaiBill · · Score: 1

    Now you have me wondering if we can make dumb people smart

    No, but you can make smart people dumb. Toxoplasmosis is spread via feces. It infects about 11% of Americans, and about 30% of people worldwide. It is correlated with lower IQ, and diminished curiosity. Infected rodents lose their fear of cats.

  43. Re:what about skinny people? by Anonymous Coward · · Score: 0

    "See picture [ytimg.com]. It's just like a big bowl of yummy pasta!"

    Thank you so much. I choose to believe that picture is of pasta carefully prepared by medical professionals, no matter what you say.

  44. Can you get a Donor Card for that ? by Anonymous Coward · · Score: 1

    Fecal transfers, for people who give a shit.

  45. Re:Intestinal infection, don't jump to conclusions by Anonymous Coward · · Score: 1

    There does seem to be a correlation between certain bacteria in the gut and obesity.

    Part of the problem in determining what is cause and effect here is that most gut bacteria can't be cultured artificially in the lab. That ofc. means they can't really be studied.
    Some gut bacteria are known to be beneficial for their host (Koalas can only survive eating the eucalyptus leafs they live off because of their gut flora. One of the first duties of a young Koala being carried by it's mom is to eat her poop to innocculate it's gut with the bacteria). So changes in metabolism due to bacteria in your gut are not only in the cards, but there is known precedence for it.

    The role of the gut flora in health and illness is a pretty knew and hot research topic.

  46. BS, with readily available proof by nazsco · · Score: 0

    it's easy to test this hypothesis.

    kill all gut bacteria from fat people and see if they thin in some cases.

    and since in the usa almost everyone takes massive doses of antibiotics for even bad hair day, i think this is debunked with readily available data already.

    1. Re:BS, with readily available proof by DexterIsADog · · Score: 1

      it's easy to test this hypothesis.

      kill all gut bacteria from fat people and see if they thin in some cases.

      and since in the usa almost everyone takes massive doses of antibiotics for even bad hair day, i think this is debunked with readily available data already.

      I volunteer you for this study.

    2. Re:BS, with readily available proof by itzly · · Score: 1

      and since in the usa almost everyone takes massive doses of antibiotics for even bad hair day, i think this is debunked with readily available data already.

      It's not sufficient to kill existing bacteria. You need to replenish the gut with the proper bacteria to test the hypothesis. Also, you need a good diet to sustain the bacteria that you want to keep.

    3. Re:BS, with readily available proof by Anonymous Coward · · Score: 0

      Wouldn't that just make them fatter? Since the bacteria eat the fat and all...

    4. Re:BS, with readily available proof by ceoyoyo · · Score: 1

      Look at it the other way. They feet cattle antibiotics to make them gain weight. Americans feed themselves antibiotics and. ?

      It's possible that something in the gut biota can be put off kilter by antibiotic treatment and that's responsible to the (so far poorly understood) correlation between antibiotics and weight gain.

    5. Re:BS, with readily available proof by Anonymous Coward · · Score: 0

      >> kill all gut bacteria from fat people and see if they thin in some cases.

      > I volunteer you for this study.

      Yep. We'd get rid of a lot of engineers that way... made me lol a lot, thx!

    6. Re:BS, with readily available proof by beelsebob · · Score: 1

      It may not be quite that simple.

      1) After killing off the gut bacteria, the chemical balance of the gut may still favour those same bacteria re-growing
      2) It may be that the presence of certain bacteria is what's necessary to lose weight (e.g. maybe there's bacteria that eat substantial amounts of your calorific intake and convert it to something undigestible), and it turns out that in this case the introduced bacteria out-competed these useful weight loss bacteria.

    7. Re:BS, with readily available proof by michelcolman · · Score: 1

      Their gut bacteria are simply resistant to the usual antibiotics since they are constantly exposed to them.

  47. Re:what about skinny people? by Anonymous Coward · · Score: 0

    I think you're confusing mental circuits with behavior. Successful people in today's society have reduced mental capacity to be inhibited by things like empathy, but they still (at least in many cases) do not act solely out of self-interest. There's always one group of people that thinks by simply ignoring the feelings of others they can reap their 'deserved' rewards of dominating society, but they are building a large-scale psychic tension that harms society, and ultimately, whatever these few egomaniacs have built for themselves.

  48. Re:So What are you saying now by Anonymous Coward · · Score: 0

    top believing in science. Trust in logic and reason instead. (they r mutually exclusive).

    This is true. Science is empirical, which means truth is a function of evidence. Rationalism is based around logic. The problem with empiricism is that your truth is only as good as your ability to measure it. The problem with rationalism is that it's easily possible to have a rational truth or system of truths that do not describe the real world.

    some bullshit research made up by someone with an agenda to 'prove something scientifically'

    Science doesn't prove things. It doesn't try to prove things. At best you can rule out alternative theories. But I'm sure you know better.

    Great troll though. All of this talk about faggots has got me a bit turned on; mind if I stop by for a quick rimjob? Don't give me that look; I just want to help you lose weight...

  49. Re:Intestinal infection, don't jump to conclusions by Anonymous Coward · · Score: 0

    Yes, it's worth looking into, but this particular story is not an all-else-equal observation. She did not just change the flora in an otherwise healthy gut.

  50. Re:what about skinny people? by Immerman · · Score: 1

    I don't disagree - but we've got how many thousands of years of civilization under our belts? And the psychopaths are still on top.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  51. Re:what about skinny people? by Immerman · · Score: 1

    Can you name a single primarily psychopathic society to provide even anecdotal experimental evidence for your claim? Theory is nice and all, but is notoriously inapplicable to human behavior.

    Also, of what concern is that to the parents who can afford to have their children "enhanced"? All they have to do is ensure that most people can't afford "upgrades" and their children will make out like the bandits they were designed to be.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  52. Re:what about skinny people? by Anonymous Coward · · Score: 0

    And I think I'm just about done with this world now.

  53. Bon Bon Transplant by Anonymous Coward · · Score: 0

    Perhaps she mistook fecal matter for Bon Bons and underwent several dozen "transplants" per day.

  54. Re:what about skinny people? by freeze128 · · Score: 1

    So all those people who have been telling me to "eat shit" have just really been concerned about my health. Boy, have I completely misinterpreted that phrase!

  55. Re:what about skinny people? by itzly · · Score: 1

    There's a difference: people on the top are often psychopaths, but being a psychopath doesn't get you an automatic place on the top. There's only so much room there.

  56. Re:what about skinny people? by Ambvai · · Score: 2

    ...Well, I'm not eating for the rest of the day.

    Here's the Youtube video from which that image is from. https://www.youtube.com/watch?...

  57. It had nothing to do with food intake? by Anonymous Coward · · Score: 0

    We have the solution to world hunger!

  58. Thermodynamics by Anonymous Coward · · Score: 0

    The mass has to come from somewhere. That person might have had gut issues that allowed her to stay thin on a diet that'd represent a significant surplus over that of a normal person. Now with a proper working gut, food's being digested that was passed through before. So she ballooned.

    That she however didn't slim down on a supervised medical diet, is just not possible. She probably cheated during that.

    1. Re:Thermodynamics by Anonymous Coward · · Score: 0

      Or her new gut can digest dietary fiber, giving her double the Calories that are on the label.

  59. Uh oh by Anonymous Coward · · Score: 1

    More excuses for fat people to keep stuffing themselves, because clearly their obesity is caused by anything but their diet!

  60. Nope. by PopeRatzo · · Score: 1

    I'm just about to have lunch, thanks.

    --
    You are welcome on my lawn.
  61. Re:what about skinny people? by DexterIsADog · · Score: 1

    Can you name a single primarily psychopathic society to provide even anecdotal experimental evidence for your claim? Theory is nice and all, but is notoriously inapplicable to human behavior.

    I am not at all providing this as any evidence for the GP's claim, I'm just mentioning one of my favorite books by Frank Herbert; "The Dosadi Experiment". A planet full of sociopaths makes for a dangerous environment.

  62. Re:what about skinny people? by FatdogHaiku · · Score: 1

    Now you have me wondering if we can make dumb people smart, and mean people nice. We may achieve world peace through fecal transplants.

    That sounds like a load of crap...

    --
    You have the right to remain sentient. If you give up the right to remain sentient, you will be elected to public office
  63. Re:what about skinny people? by Immerman · · Score: 1

    At the top perhaps, but there's *always* an "above my current position"*, and psychopathy seems to help with the climb. Sadly.

    * Well, at least until you've become god-emperor.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  64. Or our calorie measurement methods need updating by Anonymous Coward · · Score: 5, Informative

    You may find this article informative.

    Calorie measurements of food are just estimates, the particulars vary. The gut bacteria of fat people absorb more of the available energy than that of skinny people, but our measurements of the calories in food aren't necessarily the max amount that could be absorbed.

    To put it simply, fat people get more calories from the same food than skinny people, regardless of how many calories the label says the food has.

  65. Re:what about skinny people? by bytesex · · Score: 1

    'Amount of empathy' is a scale. People at the bottom complain about everybody else. People at the top don't understand what everybody's complaining about. Most of us are in the middle, doing both things.

    --
    Religion is what happens when nature strikes and groupthink goes wrong.
  66. If this wasn't .... by PPH · · Score: 1

    ... an episode of House MD, it should have been. I'd watch it just for the wisecracks.

    --
    Have gnu, will travel.
  67. Re:Intestinal infection, don't jump to conclusions by Solandri · · Score: 2

    She wasn't overweight when she had a persistent intestinal infection and gained weight after it was cured. She might well be eating more simply because it doesn't cause her discomfort anymore, or her body uses fewer resources because it doesn't have to fight an infection, or her colon has become better at absorbing the nutrients in her food because it's no longer infected.

    Actually, according to TFA, she was overweight prior to the treatment, with a BMI of 26 (which is borderline overweight). So yeah, I think your explanation is probably the likely one.

  68. True but meaningless by Anonymous Coward · · Score: 0

    What you're saying is absolutely correct and totally meaningless because you can't answer this question: how many calories do you burn every day?

    We have estimates of what a normal healthy person burns on a daily basis but every person is different. I'm somebody who will, over time, gain weight, because what feels like the right amount of calories turns out to be more than what I actually need. On the bright side for me is that overall I seem to be near average in terms of what my body burns on a daily basis. So I can do the simple math of calories in and calories out and manage to lose or maintain weight. It sucks to have to do it, and I get lazy about it, but in the end, it's possible for me to do it.

    For others, it's much harder. Their metabolism may be unnaturally low to begin with. As they try to diet, their metabolism can react and push them to burning fewer calories, having less energy, etc. It makes it very difficult for them to control their weight.

    What's interesting about this article is that it provides a very good indicator for something that may be a factor in why this is harder or easier for people. That the biome in your gut could make a huge difference in your ability to maintain a healthy weight. There could be any number of factors at play there. Perhaps some microbe makes you hungrier so that it can get more energy? Perhaps obese people are able to extract more calories from food because of what's in their gut?

    So yes, you are correct, but it's very hard for somebody to know exactly what their body burns and exactly what they put into their body.

  69. Re:what about skinny people? by Anonymous Coward · · Score: 0

    Yeah, if you kill off all the existing gut microflora first. Some bugs are better than others in breaking materials down into absorbable nutrients. If you've got bugs that are particularly poor at breaking down stuff, you're going to have a had time gaining weight. If you've got much more efficient bugs, you're going to have a hard time losing weight.

    The kinds of bugs living in the digestive tract varys widely from person to person.

  70. Re:what about skinny people? by Lynal · · Score: 1

    No, game theory tells us that sociopaths do well in a society that is primarily composed of non-sociopaths, but do not do so well in a society where they are the majority (and that society also doesn't do well as a whole).

    Please check your source on this, I do not think you can conclude that based on game theory, or even a reasonable application of game theory. Alternatively, how do you reach this conclusion?

  71. Re:what about skinny people? by whoever57 · · Score: 3

    Can you name a single primarily psychopathic society to provide even anecdotal experimental evidence for your claim? Theory is nice and all, but is notoriously inapplicable to human behavior.

    That's the point, isn't it? There are no primarily psychopathic societies because they are unsuccessful -- they die out too quickly to create records.

    --
    The real "Libtards" are the Libertarians!
  72. Re:what about skinny people? by bytesex · · Score: 2

    It's correlated with *increased* curiosity. Hence the loss of fear.

    --
    Religion is what happens when nature strikes and groupthink goes wrong.
  73. Skinny people were right by Anonymous Coward · · Score: 1

    The obvious problem is that the transplant reduced her willpower.

  74. Actually a case to sue, or not? by angel'o'sphere · · Score: 1

    The fact that a huge percentage of obese people 'suffer' from gut bacteria that split fibers into carbs is known since nearly 20 years. (I know it that long, so I guess the 'scientific community' knows it even longer)

    I believe a doctor who is transplanting such bacteria should be aware of that ... and at least test the source first.

    Playing dumb later is even worth.

    --
    Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    1. Re:Actually a case to sue, or not? by Anonymous Coward · · Score: 0

      Do you have a link for that 20 year thing? I'm having trouble googling it

  75. Re:what about skinny people? by Anonymous Coward · · Score: 3, Funny

    >It's just like a big bowel of yummy pasta.

    There, fixed it for ya.

  76. Re:what about skinny people? by Immerman · · Score: 1

    Your evidence please? I mean, it could be, just possibly, that we have never had such a society at all. A ridiculous claim, I know, except that psychopaths probably mostly all realize that non-psychopaths make much easier prey, and why would any predator want to leave a society of prey to join one consisting only of fellow predators who will have no one to prey on but each other?.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  77. make me think of by Anonymous Coward · · Score: 0

    http://youtu.be/8fgub5zkBVk

  78. Re:what about skinny people? by ceoyoyo · · Score: 1

    Perhaps that's why he said "game theory tells us."

  79. Re:what about skinny people? by turning+in+circles · · Score: 1

    Can you name a single primarily psychopathic society to provide even anecdotal experimental evidence for your claim? Theory is nice and all, but is notoriously inapplicable to human behavior.

    Lord of the Flies.

    --
    Might as well face it I'm addicted to data.
  80. Re:what about skinny people? by fahrbot-bot · · Score: 1

    I know its a joke, but not really. At the end of the day, humans are just fairly complicated machines, or even just a big complex chemical reaction.

    We are all just biological containers for our poop bacteria overlords.

    --
    It must have been something you assimilated. . . .
  81. Re:Intestinal infection, don't jump to conclusions by ceoyoyo · · Score: 1

    There's quite a bit of animal data from controlled studies. You're right, this is just an anecdote, but it does suggest that the same things might be effective in humans.

  82. Could be worse... by fahrbot-bot · · Score: 2

    ... the Macrobiome in her Gut Fauna could have been out of whack.

    --
    It must have been something you assimilated. . . .
  83. Re:what about skinny people? by Immerman · · Score: 1

    Fiction need not apply.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  84. Re:Or our calorie measurement methods need updatin by Anonymous Coward · · Score: 0

    *sigh* Only idiots up vote links to business insider.

  85. Re: what about skinny people? by Anonymous Coward · · Score: 0

    Prison? The psychos kill each other leaving the docile to just watch cuz they're no fun.

  86. Half true by aepervius · · Score: 1

    You do not gain 18 Kg of lipid tissues in short time with eating borderline normally. You have to eat way more than you need. It may be that some people have so inefficient guts that they metabolize their food badly, but the law on matter and energy conservation are still valid > when you get fat that quickly it is because you eat far more than you need and you do ntoyhing to rein yourself.

    --
    C. Sagan : A demon haunted world:
    http://www.amazon.com/gp/product/0345409469/
    visit randi.org
    1. Re:Half true by DexterIsADog · · Score: 1

      You missed my point, which was the GP's post was an absolute statement which was absurd on its face, because of obvious alternative possibilities, one of which I mentioned.

      You can argue the specifics of this woman's case all you like and it doesn't affect the point I was making.

  87. Re:what about skinny people? by Anonymous Coward · · Score: 0

    If a fat person eats skinny people shit will they lose weight??

    https://addons.mozilla.org/en-US/firefox/addon/curvytofat/?src=cb-dl-created

  88. Re:Or our calorie measurement methods need updatin by Anonymous Coward · · Score: 0

    Yep, maybe the people who keep insisting that it is simply a matter of calories in vs exercise should do a study on the calories present in the waste of skinny people vs fat people. It could very well be that skinny people have less efficient digestive systems and more food is passing through undigested than with obese people.

  89. Re:what about skinny people? by toonces33 · · Score: 4, Funny

    I am not going to take any shit from you.

  90. Re:Or our calorie measurement methods need updatin by Anonymous Coward · · Score: 1

    Then obviously fat people need to eat even less food than originally thought and much less than skinny people. The answer to weight gain is still diet and exercise even if the same diet doesn't work for two people. If you are able to pull more calories out of the same amount of food you may need to supplement with vitamins to get the needed amount but eating less is still the answer if you are over weight.

  91. Re:what about skinny people? by DexterIsADog · · Score: 1

    I'm not sure what your post is supposed to mean, but mine just means, "hey, that reminds me of this great book!". As I said.

  92. The fatty and the turd by Anonymous Coward · · Score: 0

    we may never know which came first.

  93. Re:what about skinny people? by ceoyoyo · · Score: 1

    Sorry, was meant to reply to the parent of your post.

  94. Re:what about skinny people? by Anonymous Coward · · Score: 0

    No, game theory tells us that sociopaths do well in a society that is primarily composed of non-sociopaths, but do not do so well in a society where they are the majority (and that society also doesn't do well as a whole).

    Your assumption of rational decision making is foolish. "I got mine, fuck you" means that the consequences are irrelevant until after they have already occurred. "Tragedy of the Commons" has a name for a reason.

  95. Re:what about skinny people? by lister+king+of+smeg · · Score: 1

    Can you name a single primarily psychopathic society to provide even anecdotal experimental evidence for your claim?

    Congress?
    sociopath check
    dysfunctional check

    --
    ---Saying gnome 3 is better than windows 8 not so much a compliment as it is damning with light praise.
  96. Re:what about skinny people? by Grishnakh · · Score: 1

    I used to have a girlfriend who pronouned "bowl" that way.

  97. Who needs a donut? by Anonymous Coward · · Score: 0

    You sound fat. Stop defending your gluttony and greed.

  98. LITERALLY Fuck Off by Anonymous Coward · · Score: 1

    He LITERALLY does eat. L2Grammarz n00b.

    1. Re:LITERALLY Fuck Off by Opportunist · · Score: 1

      Actually, he does literally. Lately he choked on a chicken bone.

      But jumping to conclusions makes you figuratively an asshole.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  99. Oh look! by Anonymous Coward · · Score: 0

    This could be the first time that the opinion of someone who drinks poo is relevant, Drinkypoo. Carry on!

  100. Re:what about skinny people? by Anonymous Coward · · Score: 1

    >> Now you have me wondering if we can make dumb people smart

    > No, but you can make smart people dumb.

    And, possibly, fat.

    Occasionally, we might learn of a beach deemed improper because of the danger of getting fat.

  101. Amazing by Anonymous Coward · · Score: 0

    This is middle ages technology

    it's amazing how medical science is so advanced
        and yet it still is learning simple things.

    The AMA and doctors have the state sponsored monopoly on preserving and advancing medical science.
    Sometimes I wonder if this is a good bargain.

  102. ORLY? by Anonymous Coward · · Score: 0

    Even when you do it right, your conclusion is more than likely going to be wrong.

    Could you provide me some statistics that support that, please?

  103. Re:what about skinny people? by narf0708 · · Score: 1

    Way to deny the existence of free will. Saying that everything we do is just a function of nature vs. nurture doesn't account for the idea of volition. And if we don't have a choice over what we do, the entire concept of ethics and justice becomes nonexistent. You don't put asteroid into jail for killing someone(as unlikely as it may be) because an asteroid doesn't have a choice. We put people in jail for murder because, at some point, they made a decision to murder another person. If murder is simply a function of nature and/or nurture, the person can't be held accountable for their crime, and thus they cannot be justly punished.

    Sure, there is a lot than can be accounted for by nature/nurture, but that view of humanity is incomplete. Accounting for the ability to choose is what completes it, and we need to keep that in mind in order to not throw meteorites in jail and otherwise maintain the possibility of order and sanity in society.

    --
    "Violence is not the answer. Violence is the question. The answer is yes."
  104. Re:Intestinal infection, don't jump to conclusions by Anonymous Coward · · Score: 0

    That was my point exactly: This anecdote provides too little data to say that it suggests a particular cause-effect relationship. It leaves room for that explanation, but there are several other (I'd say more) plausible explanations for the observed symptom under these circumstances.

    The recommendations for healthy eating and weight loss are all over the place. There are myriads of dietary approaches, often contradictory, and even the targets for weight, body fat, etc. are inconsistent. Actual science for once instead of jumping to conclusions again and again would really help. If people start swallowing shit pills instead of probiotic yogurt and in a couple of years it turns out that it was all for naught, there's going to be a real shit storm.

  105. Re:what about skinny people? by Bill+Dog · · Score: 2

    Even if it's delivered to your location via... stool pigeon?

    --
    Attention zealots and haters: 00100 00100
  106. Re:what about skinny people? by Smallpond · · Score: 2

    Probably referring to the Prisoner's Dilemma which is a payoff matrix that results in trusting players doing better than rational players.

  107. But but but "obesity epidemic" is just a metaphor! by Baldrson · · Score: 1

    Certainly, we should all be celebrating the diversity of gut flora brought to all shores of all nations by all shores of all other nations. Let us not permit this minor incident to instill in anyone the virulent notion that "obesity epidemic" is but a poorly chosen metaphor for the lazy stupid fat citizens of the US who should be replace by vibrant immigration.

  108. Let me be the first to say it by Anonymous Coward · · Score: 0

    She's full of shit.

  109. Re:what about skinny people? by jimmydevice · · Score: 1

    What? Full of Shit?

  110. Re:what about skinny people? by dreddnott · · Score: 2

    Free will is an illusion and the 'ability to choose' is a legal and social construct. You are wrong.

    --
    I may make you feel, but I can't make you think.
  111. Re:what about skinny people? by fustakrakich · · Score: 1

    Can you name a single primarily psychopathic society...?

    Jeeze, all of 'em. Try to understand how irrational people are, one of the things that make psychopathic charisma so effective. It's why the whole concept of economic and most social studies are a complete fraud. If the world wasn't ruled by psychopaths, we would be at total peace with each other, with little more bickering than who gets to have the car on Friday night. I consider that pretty good evidence of your 'psychopathic society'.

    --
    “He’s not deformed, he’s just drunk!”
  112. Re:what about skinny people? by Anonymous Coward · · Score: 1

    Oh no, that's where you're wrong. The republicans wear the red noses for hire. The democrats are the charismatic, and very deceitful psychopaths, playing the weakling like everything is out of their control and therefore must 'compromise' with the other side.

  113. Captain obvious by Anonymous Coward · · Score: 0

    OK, so here is the obvious thing. If you have a life saving procedure that kills all the bacteria in your gut, and you then suffer horribly because your gut bacteria is gone (and the list of ailments is long), instead of more, highly invasive and dangerous, procedures, doctors are giving people a pill which contains the bacteria of another persons gut. They used to give them feces (poop) but most people would object, so they process it, remove the water and the smell, and then turn it into a coated pill. You taste and smell nothing. And the recoveries have been immediate and permanent. But people are becoming fat because donors might be overweight. So they screen to avoid that. Ok Doctors, here's the BIG FAT hint. If some people are getting fat after ingesting someone else's gut bacteria, then the problem isn't in screening, the problem is a component of the gut bacteria. Find out what that component is, and remove or restrict it, and then both the donor, *and* the contributor will be skinny. OBESITY is a HUGE problem. If its caused by gut bacteria, then FUCKING FIND THE COMPONENT IN THE GUT BACTERIA AND FIX IT!!!!! Instead of weight loss programs, diet and diet and diet and diet and exercise till you're muscles are burning and your body is breaking and you still can't take off the weight, change the gut bacteria. There is a component in gut bacteria that is *HIGHLY* suspected in causing autism. For hundreds of years doctors didn't believe that bacteria could live in the gut and believed stomach ulcers ware caused by too much acid (overproduction). It wasn't until they heard the words "heliobactor pylori" and saw evidence did they start to believe (and many still didn't for years). There is a component in your gut that can cause autism, there is a component in your gut that makes you fat, and there are bacteria that can live in hydrochloric acid and thrive. Research the problem, find the problem, fix the problem.

  114. Re:what about skinny people? by fustakrakich · · Score: 1

    Toxoplasmosis is spread via feces....

    It's correlated with *increased* curiosity.

    Ahhhh, it all makes sense now.

    --
    “He’s not deformed, he’s just drunk!”
  115. How Much?? by Anonymous Coward · · Score: 0

    My first thought was.. how much did they stuff in her??!?!

  116. Re:what about skinny people? by Anonymous Coward · · Score: 0

    That's some heavy shit.

  117. Re:what about skinny people? by Shados · · Score: 1

    Thats already an issue. Lots of people don't end up in jail because of "they had mental issues!! omgomgtheyarevictims!" or they did what they did because they had a tough childhood and somehow its a factor that reduces their sentence.

    The most we discover, the worse it gets. You have the ability to choose, of course. But what do you think makes your choices, beyond outside factors/uprising + hormones/biology/etc.

    Hell, how well you slept last night probably affects your choices more than free will ever did.

  118. Re:what about skinny people? by narf0708 · · Score: 1

    You're saying that you have no right to seek justice, or even care at all, if someone tortues and/or murders your family, simply because that person had absolutely no choice in the matter, no more than a rock can stop itself from falling. Just making sure you understand the logical implications of your determinism here.

    --
    "Violence is not the answer. Violence is the question. The answer is yes."
  119. Re:what about skinny people? by Anonymous Coward · · Score: 0

    > I am not going to take any shit from you.

    Fine. See if I give a shit!

  120. Re:what about skinny people? by Anonymous Coward · · Score: 0

    Chechnya is run by a psychopathic culture. Result: violent and underdeveloped country. Saudi Arabia? Afghanistan? Same. The lucky ones have oil, that's about it.

  121. Re:Or our calorie measurement methods need updatin by Maxo-Texas · · Score: 1

    Except the physical amount of food they need to eat is so small that eating the "right" amount leaves them feeling ravenous all the time.

    The feedback mechanism from their stomach is out of touch with their intestines.

    Imagine if you suddenly only needed 3 table spoons of food per day to keep your body running and anything else was stored as fat.

    You'd feel terribly hungry all the time.

    --
    She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
  122. Delivery by Anonymous Coward · · Score: 0

    It's the delivery method, stupid! The shit hit the fan, is all.

  123. This is fascinating! by Evtim · · Score: 1

    Truly it is! There is a lot of noise recently about healthy gut and its profound influence on almost every aspect of our health. Good!

    Back in the days of my biotechnology college education I learned a profound truth that I forgot for many years after that [partially because I went off doing physics and chemistry instead], until my own health got damaged due to unbalanced gut flora. A truth that most people on Earth are not aware off. And then I remembered....that this is not the planet of the apes, nor the planet of the mammals, birds, reptiles or whatever. This was, is, and will forever be the planet of the microorganisms! All the rest of life is just an overlay on top of the microbial ecosystem. The microbs are everything. Without them there is no complex life possible on any level. They determine or have profound influence on almost everything about life.

  124. Re:what about skinny people? by RespekMyAthorati · · Score: 1

    Perhaps at the quantum mechanical level, but that has nothing to do with human behavior. Human behavior is determined at a much higher level of abstraction that includes ethics, morals and the consequences of our actions.

  125. Re:what about skinny people? by davester666 · · Score: 1

    Yes. Politicians have been feeding us shit for a long time, and it seems to have slowly made most people dumber and more apathetic.

    --
    Sleep your way to a whiter smile...date a dentist!
  126. Re:what about skinny people? by okoskimi · · Score: 1

    Invoking the "murder your family" argument is equivalent to Godwining the discussion. You are trying to make an emotional appeal that overrides logical consideration.

    That being said, in the "no free will" worldview - which I do not necessarily share - laws and punishments are part of the equation. Even if a person has no free will in the sense that his decisions are considered to be predetermined given his circumstances, law and punishments are part of the circumstances and will affect the decision. Even without self-determination, whether something is forbidden / punishable will affect the outcome. However for that effect to be in force the punishment must also be implemented. So while "justice" might not really be an applicable concept, laws, punishments and the concepts of right and wrong certainly are.

    If anything, considering human decisions to be deterministic makes for a more cold-blooded judicial system. If you think that a person, given exactly the same circumstances, might act differently on different occasions because of self-determination, then you can't really write off that person as a lost cause. If, on the other hand, you believe that given the same situation the person will make exactly the same decision, then your only choice is to make sure the same situation never arises again. Sometimes this can be accomplished through non-violent means. Sometimes not.

  127. Perfect, before. by Anonymous Coward · · Score: 0

    Kind of like a superpower being able to live on a small energy intake. Must have been an awesome trait 100 years ago. Something to export to third word countries?

  128. Yes by Martin+S. · · Score: 1

    Yes, links have been established with increase of antibiotic use and increase in weight. When I read the summary this was the first thing that came to mind as the likely cause.

    http://www.bbc.co.uk/news/heal...

    http://www.theguardian.com/sci...

  129. Re:what about skinny people? by michelcolman · · Score: 1

    Your logic is flawed. Let's assume for a minute that people's actions are predetermined. That means you are still free to do whatever you want, but someone with perfect information about the universe and your brain is able to tell in advance what you will want to do. It doesn't matter for you, you couldn't even tell the difference because you just do whatever it is you want to do, whether you had "free will" (whatever that means) or not.

    In that case, if our actions are predetermined, locking up criminals still makes perfect sense. We don't lock up criminals out of revenge, we lock them up to reduce crime. The fact that people know they can be locked up for certain crimes may deterministically keep them from wanting to do that crime. And people who have been punished, may be (hopefully) less likely to do it again. And of course society is safer during the period they are in jail. You might say "it's not fair, because they couldn't help it", but that doesn't matter. In fact, the existence of punishment may actually help a lot of would-be criminals by keeping them from becoming a criminal in the first place.

    Animals are often killed after attacking humans. Not because we are angry at them, or because we fell it is "just", but simply because we don't want that kind of animals around. Makes perfect sense, whether they have free will or not.

    Really, what's the difference in "justness" between punishing someone who, out of "free will", killed a man or someone who killed a man because his brain happened to be wired that way? In both cases, we consider him to be bad person and we hope the punishment will prevent more murders in the future by that person or others.

    Why do we punish children? Because we want them to learn the consequences of their actions and grow up to be responsible people. In a way we're just programming them.

  130. Re:what about skinny people? by michelcolman · · Score: 1

    Those doctors seemed to think it was rather funny :-)

  131. Re:Or our calorie measurement methods need updatin by Anonymous Coward · · Score: 1

    Imagine if you suddenly only needed 3 table spoons of food per day to keep your body running and anything else was stored as fat.

    Is this 3 tablespoons of uranium? If you aren't referring to a nuclear reaction, then what you claim is thermodynamically impossible. Using real food data, let's give you the benefit of the doubt and say you were referring to pure fat, which has the highest energy density of all our nutrients. Here you go: 3 Tbsp of butter would be 300 kcal.

    The metabolic rate for a comatose patient is above 1,000 kcal/day. Someone who is awake will burn more than that.

    So, no, you're wrong.

    Look here, brass tacks, thermodynamically: Heat Transfer and the Human Body

    Take a body surface area of approximately 1.9 m^2, an ambient temperature of 21 C (~70 F), and an effective clothed skin temperature of 30 C (86 F). Therefore we end up integrating (2.6 * (30 - 21) * 1.9 watts) over a period of a day, which yields ~3.8 megajoules/day == 917 kcal/day == 917 food Calories/day.

    Furthermore, the preceding calculation is for a human-sized rock that perfectly converts energy to thermal energy, not a biological organism relying on inefficient metabolic processes and which also has to power movement like a human does, etc.

    Yes, there are differences between people in intestinal absorption of food nutrients and so forth, but there is a fixed lower limit after which thermodynamics applies. What is far more likely is that these people who claim they are failing to lose weight are consuming more caloric energy than they believe they are.

    You'd feel terribly hungry all the time.

    That's probably true, given the effect of leptin secreted by extra fat cells (remember fat cells multiply but then they stick around even if you lose the weight). However, that has no bearing on the violation of thermodynamics inherent to these "I ate nothing but 1,000 kcal a day and I gained fat!" claims. That's impossible.

  132. Sick to my stomach by Anonymous Coward · · Score: 0

    I read this at Taco Bell right after I ate lunch. Bad timing. Gee, thanks.

  133. Re:what about skinny people? by easyTree · · Score: 1

    So, thin people have fat/greedy bacteria and vice versa?

  134. Interesting by kilodelta · · Score: 1

    So in essence the guy bacteria determine obesity levels. Perhaps they are too efficient at extracting nutrient.

  135. Re:what about skinny people? by Anonymous Coward · · Score: 0

    Also can't point to any society with 100-foot-tall people to see their difficulties, even though we know what it would be due to the cube-square law.

  136. Re:what about skinny people? by AmiMoJo · · Score: 1

    You're only saying that because of the chemicals in your brain.

    --
    const int one = 65536; (Silvermoon, Texture.cs)
    SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
  137. Re:what about skinny people? by WolfWithoutAClause · · Score: 1

    **And unless the god-emperor has a cat

    --

    -WolfWithoutAClause

    "Gravity is only a theory, not a fact!"
  138. Re:what about skinny people? by WolfWithoutAClause · · Score: 1

    Toxoplasma is not really a great example, it's correlated with slightly higher IQ if anything.

    A better example is iodine deficiency which causes cretinism-> much lower IQ.

    --

    -WolfWithoutAClause

    "Gravity is only a theory, not a fact!"
  139. Shitty. by msobkow · · Score: 1

    :P

    --
    I do not fail; I succeed at finding out what does not work.
  140. Thanks for interesting anectode on breathing well by Paul+Fernhout · · Score: 1

    And now that I search on that: http://www.medicalnewstoday.co...
    "Majority of weight loss occurs 'via breathing' ... According to researchers from the University of New South Wales in Australia, when weight is lost, the majority of it is breathed out as carbon dioxide. Their paper is published in the Christmas issue of The BMJ. Prof. Andrew Brown and Ruben Meerman reported widespread misconception regarding how weight is lost, finding physicians, dietitians and personal trainers all equally guilty of not knowing. ... The results suggest that the lungs are the main excretory organ for weight loss, with the H20 produced by oxidation departing the body in urine, feces, breath and other bodily fluids. On average, a person weighing 70 kg will exhale around 200 ml of CO2 in 12 breaths each minute. The authors calculate that each breath contains 33 mg of CO2, with 8.9 mg comprised of carbon. A total of 17,280 breaths during the day will get rid of at least 200 g of carbon, with roughly a third of this weight loss occurring during 8 hours of sleep. ..."

    I've heard stuff now and then from Andrew Weil on breathing, and breathing well is at the core of Yoga, but your anecdote helps me make a better connection to all that. It may indeed apply very broadly. Thanks!

    I've heard in general exercise is great for health (gets the lymph moving to boost the immune system, to begin with), but in general it does not affect weight loss much because people who exercise more tend to eat more after a workout as the body tries to compensate. However, I can wonder if changes in breathing patterns somehow work around that issue?

    I would be curious if you had any good tips on what people can do to improve their breathing along the lines of what worked for you? Are they different than, for example, these exercises suggested by Dr. Andrew Weil?
    http://www.drweil.com/drw/u/AR...

    BTW, one other thing missed in so much discussion here and elsewhere on weight is the psychological aspect. People can talk all they want about calories in and calories out, and even ignoring how the type of food and gut bacteria make a difference (as well as your point on breathing). However, as Dr. Joel Fuhrman talks about, we essentially have an "appistat" like a thermostat for hunger, and what seems to control when it shuts off is how full we feel (in terms of physical bulk of fiber and such in the stomach) and also the amount of phytonutrients and micronutrients in the food. If you are not getting either (and the Standard American Diet tends to be lacking in *both*) then it is a continual psychological battle where your body is constantly telling you that you are not finished eating because of the lack of fiber and lack of good nutrients. So you keep eating junk (like processed white bread or sugary drinks), always searching for nutrition. The calories make you fat, but your body still thinks (correctly) that it is missing something, so it goes on trying to make you eat. And studies show that 95%+ of people on diets that focus on calories restriction fail in just a few months for this psychological aspect. We only have so much self-discipline. It is generally only when we change the nature of what we eat that we change our weight. Then we are using our self-discipline for only a short time (a few weeks) to change our eating habits and related taste preferences. After that, low-nutrient junk food generally is not so appealing. See also:
    "How to Escape the Pleasure Trap"
    http://www.drfuhrman.com/libra...

    Although, your point on breathing certainly is another angle on that. As is the general issue on gut bacteria, since both of those affect how much of our food's energy is burned (without really changing much else) or how much is collected or goes through the gut. So, I'm

    --
    A 21st century issue: the irony of technologies of abundance in the hands of those still thinking in terms of scarcity.
  141. Even if you avoid obesity, your arteries can clog by Paul+Fernhout · · Score: 1

    That reduces blood flow to the brain as well as other vital organs. That clogging is typical on the Standard American diet, which causes arterial inflammation in multiple ways including sugar spikes and then supplies "bad" fats to repair them (as opposed to "good" fats which we absolutely need). Sadly, the first obvious symptom of clogged arteries may be death from a heart attack or stroke. Even when people detect clogging in the heart and put in stents to temporarily (ofter a few months) deal with it, stents do nothing for clogs in your brain or liver or elsewhere.

    Check out the writings of people like Dr. Andrew Weil, Dr. Joel Fuhrman, or Dr. Caldwell B. Esselstyn for a better way to eat that will also improve your brain power to be a better software developer.

    In essence, the advice is eat more vegetables and fruits and beans, eat healthy fats like from avocados and nuts and/or free range pasture-fed animal products, get enough iodine like from seaweed and vitamin D from sunlight or supplements and B complex depending on other food sources, get extra micronutrients from seeds, eat whole grains meaning you can see the actual whole grain like a barley kernel in your food, eliminate most refined and processed foods including stuff made with white flour and processed sugar and especially processed meats with additives, eliminate synthetic additives like synthetic colorings and synthetic flavorings, avoid food with bromine in it as in many dough conditioners for breads, and so on. In general, eat a variety of foods of a variety of different colors (the colors reflect different essential phytonutrients). There are lots of nuances, and some things may not work well for everyone depending on your gut bacteria and genetics and lifestyle, so it may be a bit of a learning curve for what works for you. Most of that battle is actually won or lost in the supermarket, because once food is in the home, it is almost certain it will be eaten in reverse order of healthiness for various psychological and adaptive/evolutionary reasons.

    See also this advice for if or more likely when you do fail a "stress test" for your heart and your cardiologist tries to rush you into getting a bunch of stents:
    http://www.drfuhrman.com/libra...
    "The sad thing is surgical interventions and medications are the foundation of modern cardiology and both are relatively ineffective compared to nutritional excellence. My patients routinely reverse their heart disease, and no longer have vulnerable plaque or high blood pressure, so they do not need medical care, hospitals or cardiologists anymore. The problem is that in the real world cardiac patients are not even informed that heart disease is predictably reversed with nutritional excellence. They are not given the opportunity to choose and just corralled into these surgical interventions. Trying to figure out how to pay for ineffective and expensive medicine by politicians will never be a real solution. People need to know they do not have to have heart disease to begin with, and if they get it, aggressive nutrition is the most life-saving intervention. And it is free."

    Sitting for long times is also problematical. Look into at least a standing desk, and maybe a treadmill workstation. Exercises and good breathing is important for health too, even if the connection to actual weight loss is more complex.

    Good luck on possibly a very long journey towards wellness. One I've been on now for many years, but with its ups and downs, wins and losses, forward movements and setbacks. A natural reaction to excessive stress is also to eat more because in the past stress meant future meals are less certain so it was good to fatten up when you could. Over the long term, the social, psychological, community, and even spiritual aspects of this entire process become very important. It's not easy to become well in our culture, with so many highly-paid people working for processed food companies whose job is to catch

    --
    A 21st century issue: the irony of technologies of abundance in the hands of those still thinking in terms of scarcity.
  142. Re: what about skinny people? by Anonymous Coward · · Score: 0

    In between the biologically driven mechanisms and the psychologically conditioned behaviour, lies an arcane layer of ineffable stupidity that inexplicably seems to guide our most incredible actions (that's ALL of us, for those who would contrarily argue this out of personal insecurity) with variable frequency.
    I suspect we will eventually establish a link between this element, and the condition of and degree to which a given individual is full of fecal matter.
    Perhaps this will enlighten us to a greater, more effective extent than psychological and biological studies have thus far?

  143. Re:what about skinny people? by Anonymous Coward · · Score: 0

    What, you actually believe these people are for real? That's funny!

  144. Re:what about skinny people? by Anonymous Coward · · Score: 0

    Maybe you should take a trip down memory lane with the Royal Family..

  145. WTF by Gallomimia · · Score: 1

    Get that shit off slashdot.

    --
    Sadly, a Libertarian cannot force his views on another, and freedom cannot spread as does the cancer known as religion.
  146. GMO Bacteria by Anonymous Coward · · Score: 0

    Wonder if it's some genetically modified bacteria Big Pharma slipped in somewhere to sell more weight loss products. Maybe a GMO Candida fungus instead, which will later result in a "Last of Us" scenario.

  147. Re:what about skinny people? by rtb61 · · Score: 1

    Far more likely some people have bacteria flora within their digestive tract that is far more efficient and breaking down food ie releasing more nutrients while consuming less themselves. So when people continue to consume food at the same levels they start to put on weight. Likely the bacteria might be more effective at breaking down cellular walls of vegetable matter releasing those nutrients for consumption. Initial entry source might be from foods contaminated by ruminant faecal matter. So people that fill themselves up on vegetable matter in order to fill full without weight gain might find themselves now tricked into gaining weight.

    --
    Chaos - everything, everywhere, everywhen
  148. Re:what about skinny people? by fodendaf · · Score: 1

    There are (though they are changing now) psychopathic headhunter societies in places like new guinea that have lived for tens of thousands of years by murdering members of other tribes, mainly as a rite of passage, although also for cannibalism. They have outlived all other collapsed civilisations, like the mayans, aztecs, romans by keeping to themselves and keeping their population down so that they do not exhaust their resources. Although kuru, or creutzfeld-jacob disease is endemic there, schizophrenia is completely absent for reasons which are inexplicable which does tend to point to them being physically and mentally healthier than most developed countries.

  149. bohica by Anonymous Coward · · Score: 0

    And people laughed when the aliens were doing all of the anal probes.

  150. Re:what about skinny people? by Anonymous Coward · · Score: 0

    Can I get fries with that patty?

  151. Re:what about skinny people? by Anonymous Coward · · Score: 0

    I can't cite you an example of an entire society of psychopaths but I can point at one psychopathic member of a society- YOU. I guess your point stands huh?

  152. Bravo by Anonymous Coward · · Score: 0

    I AM figuratively an asshole! Maybe you do know how to grammerz, bruh. Good job!

    1. Re:Bravo by Opportunist · · Score: 1

      I try my best. It can be a bit of a challenge when you know a few languages that have very different and sometimes conflicting grammar rules. Cases alone can be a headache when you switch between, say, German and Russian. At least that problem is something you can mostly ignore in English.

      Actually I'm quite glad English has such an easy and very intuitively understandable grammar structure. Compared to nightmares like Finnish or (at least to me) Russian it's been very easy to pick up. Explains why it became the de facto lingua franca.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  153. Pee ewe! by Anonymous Coward · · Score: 0

    I think thi post is full of shit!

  154. Re:Or our calorie measurement methods need updatin by Maxo-Texas · · Score: 1

    Your quibbling, missed my point, or are intentionally treating an hypothetical example as an actual example.

    First- surely you are not suggested that every person who eats the same meal absorbs exactly the same amount of calories into their system, right? Because that's crazy on the face of it. It will be on some kind of distribution curve.

    So given three people who eat "1500" measured calories of food, one might absorb 1000 calories, another might absorb 1450 calories, another might absorb 2000. In some extreme cases, some might absorb 750 calories or 3000 calories. (There are already examples in this discussion of people who can get 250 calories from a serving of brocolli while others only get 100 calories).

    The last person could only eat 750 calories worth of food per day and not gain weight. They'd probably need to take vitamins to meet their nutritional requirements. And they'd be eating so little physical food that they would feel like they were starving all the time. Whenever they ate like "normal" people, they would gain weight even if they exercised.

    Perhaps if your last statement reads: "I ate only the amount of food that most people absorb 1,000 kcal from each day and I gained fat!"

    Last factoid: I'm in the reverse case. I can eat heartily and I do not gain weight. Plenty of butter too. My weight only varies by the liquid I just drank and the food I just ate. I have a friend who must eat heartily or he loses weight because he has a kidney problem. He can't gain weight even when gorging. His body is terrible at absorbing calories from food.

    --
    She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
  155. Re:what about skinny people? by gl4ss · · Score: 1

    well, only if the person in question has access to food and keeps eating it.

    on the other hand, if she had a faulty digestive system before and then kept just eating the same way after fixing it, it's not that hard to conceive that she gained weight.

    and god forbid it being her fault of course. it's never the fatties fault that the fattie keeps eating and eating and eating and doesn't count the calories or how many cokes there can be in a day..

    --
    world was created 5 seconds before this post as it is.
  156. Re:Or our calorie measurement methods need updatin by Anonymous Coward · · Score: 0

    Your quibbling, missed my point, or are intentionally treating an hypothetical example as an actual example.

    It's not quibbling. Your type of claims are ubiquitous across the internet: people who claim they consume less energy than would be required to keep an equivalently-sized, perfectly-metabolizing, immobile rock above ambient temperature, and they still claim they are running an energy surplus sufficient for lipogenesis. I mean, it must be either that or God is sending angels down from heaven to load them up with fat, right?

    First- surely you are not suggested that every person who eats the same meal absorbs exactly the same amount of calories into their system, right?

    I'll let you carefully reread my last post and decide for yourself. Hint: you really don't have to read between the lines.

    The last person could only eat 750 calories worth of food per day and not gain weight.

    That person would lose weight due to their energy deficit. Are you somehow alleging that these people can extract more energy from food than can be obtained by fully combusting it in a bomb calorimeter (i.e. the gross energy)? That's the same magical thinking you exhibited before. For reference, I refer you to the difference between gross energy and available energy in macronutrients.

    Once you start claiming that you are gaining weight when you are consuming less than your RMR (which does not vary substantially across studies), or, hell, claiming that you are consuming less gross energy available in the mass of food you have consumed than it takes to keep one of those "magic rocks" above ambient temperature, then your claim is absolutely tantamount to magical thinking.

    Try it for yourself: calculate your BMR, calculate that mass equivalent in gross energy available in pure fat (just to make it easy to weigh out). Consume it as your sole caloric input. It is impossible to gain weight, presuming you are not pouring said food into a non-metabolizing corpse. Yes, literally impossible in this universe.

    So, when someone has a scenario where they believe they have consumed less than their metabolic expenditure (which is, of course, greater than their RMR) in caloric input and yet they claim they gained fat, which claim do you believe has been falsified: thermodynamics, or the amount of caloric input they believe they have ingested? We already know it's not the metabolic energy expenditure that's incorrect.

    Perhaps if your last statement reads

    No. My statement stands as written. If you choose to disbelieve thermodynamics then you're welcome to your false religion.

  157. Mind Control! by DarthVain · · Score: 1

    LOL! I keep thinking of that zombie fungus that some insects get that tells them to go drown themselves....

    Perhaps your stomach does have some influence over your food craving...

    "I dunno, but my gut tells me that I need to eat those donuts!" :)

  158. Re:Or our calorie measurement methods need updatin by Maxo-Texas · · Score: 1

    Last point- I agree there are people who gorge/binge eat and say they or not or that they are dieting and who then gain weight. And that's probably the most common case because food diaries work so well.

    But I am saying there are plenty of metabolic disorders which cause weight gain. And it's a fact that some stomach bugs help us digest certain foods (such as seaweed) which are indigestible for anyone lacking those stomach bugs. And heredity plays a strong factor in weight gain via several factors.

    And so it's not unreasonable that some people are just screwed when it comes to weight gain.

    (this was meant to go out last night but it got caught by the 5 minute restriction and then I forgot about it and went to bed. lol).

    --
    She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
  159. Re:what about skinny people? by Anonymous Coward · · Score: 0

    So all those people who have been telling me to "eat shit" have just really been concerned about my health. Boy, have I completely misinterpreted that phrase!

    And it wasn't "and die," it was "and dye!" They were also concerned about your physical appearance! Wow, I've really have met a lot of nice people :)

  160. Re:Intestinal infection, don't jump to conclusions by dfsmith · · Score: 1

    Arnold Schwarzenegger's BMI was 33 when he won Mr. Universe. BMI is somewhat useful in statistical analysis, but rarely relevent for a single case with no other information.

  161. What the Bible says: by dfsmith · · Score: 1

    From Genesis 41:20-21:

    The lean, ugly cows ate up the seven fat cows that came up first. But even after they ate them, no one could tell that they had done so; they looked just as ugly as before. Then I woke up.

    It was just a dream... B-)

  162. Re:what about skinny people? by RivenAleem · · Score: 1

    I don't like to quote something possibly over-used, but "Absence of proof is not proof of absence."

    To adequately prove psychopaths don't thrive in a primarily psychopathic society, we'd have to run several experiments where varying groups of people try to form a society with a range of ratios between normal and psychopathic people.

    I'd hate to be the one normal guy in that group!

  163. Re:what about skinny people? by tjbutt58 · · Score: 1

    There is some evidence to support this. Dr Karl Kruszelnicki (Australian science presenter and MD) produces an excellent series of podcasts, and a couple cover exactly this topic. The presumed mechanism was transplanting intestinal flora/fauna that were more efficient at converting non digestible material (eg, cellulose) into something the body could use.

  164. Re:what about skinny people? by Anonymous Coward · · Score: 0

    In some (many, probably) cases it's primarily the fault of the person, who is simply eating too much.

    In other cases (far more than was previously thought, and far more than people like you are likely to ever accept) it's not the fault of the person, for whom eating less and exercising more is not enough.

    In your mind, it's almost always the fatties fault. In reality, the picture is more nuanced. But that's not something you (and people like you) are likely to accept since it gives you less reason to feel superior.