Making Babies In Space May Not Be Easy
Hugh Pickens writes "Studies of reproduction in space have previously been carried out with sea urchins, fish, amphibians and birds, but Brandon Keim writes in Wired that Japanese biologists have discovered that although mammalian fertilization may take place normally in space, as mouse embryos develop in microgravity their cells have trouble dividing and maturing. The researchers artificially fertilized mouse eggs with sperm that had been stored inside a three-dimensional clinostat, a machine that mimics weightlessness by rotating objects in such a way that the effects of gravity are spread in every direction. Some embryos were ultimately implanted in female mice and survived to a healthy birth, but at lower numbers than a regular-gravity control group. Part of the difference could be the result of performing tricky procedures on sensitive cells, but the researchers suspect they also reflect the effect of a low-gravity environment on cellular processes that evolved for Earth-specific physics. '"These results suggest for the first time that fertilization can occur normally under G environment in a mammal, but normal preimplantation embryo development might require 1G," concludes the report. "Sustaining life beyond Earth either on space stations or on other planets will require a clear understanding of how the space environment affects key phases of mammalian reproduction."'"
Zero gravity probably makes the actual copulation bit kinda tricky too.
Folks at NASA have been running experiments in space for decades....where can I find results of all those experiments? Or was it money down the drain?
... but I'm willing to try!
The enemies of Democracy are
There have been all too many jokes about this topic. It is good to see some serious thought and discussion about it.
Since "artificial gravity" is easily created with rotation, conception and pregnancy would have to be within a rotating chamber at least until the embryo develops far enough to tolerate zero-G without adverse effects.
Willie...
a) sex in space: easy
b) consequences of sex in space: non-existant
I am pleased.
If I put an egg into a blender, I'm pretty sure it'd have a hard time forming a chicken too.
Why?
The challenge - it's most of the fun.
I'm sure these studies have been thoughtfully conducted and documented, though not announced, and the results were satisfactory. Humans being mammals, curious and intelligent wouldn't avoid this opportunity for experimentation even if directly ordered not to.
There is no reason to expect that their clinostat successfully captures the essence of the problem. Obviously a thorough study of 0-G human gestation will be undertaken as soon as the mission constraints allow it, whether it's in the mission plan or not. The kind of folks who venture out aren't the sort to avoid this question. If it turns out the results are unsatisfactory we will of course find a solution. We must.
Help stamp out iliturcy.
So don't do that.
Using acceleration to counteract undesirable effects of microgravity appears to be a universally ignored solution. It's like people are so amazed by how awesome zero-g is that they can't accept that working against it might be the best option.
problem: humans lose bone mass in zero-g
brain dead solution: we need to change humans with drugs! oh, and we'll make them exercise more too.
problem: embryos don't develop normally in zero-g
brain dead solution: we need to study embryonic development more, and hey, maybe we can find some drugs to fix it!
problem: transferring cryogenic propellant in zero-g is hard
brain dead solution: we need to learn more about fluid dynamics in zero-g!
Back in the Gemini days they actually bothered to join a pair of spacecraft together and spin them up. The effect was about 1000th of a g, but it was a successful mission. Everyone presumed that NASA would continue this research after Apollo, with longer tethers and slower rotation, a 1g environment could be created. That didn't happen. Instead, the fixed module concept took over and "studying the effects of zero-g" became the mantra. No matter, the Japanese space program proposed a module that would allow the study of incremental gravity on mammals, everything from low gravity to three times earth gravity, or the astronauts could sleep in it. That was scrubbed.
Meanwhile, private industry is solving the problem of propellant transfer.
How we know is more important than what we know.
There once was a time where the mention of Wired magazine wasn't enough to ensure that the rest of the summary wasn't even worth reading, much less the linked article. I am bored to tears
Organisms that have adapted to the level of gravity here on Earth don't quite work properly when put into a different environment. Shocking
I think this is going to be a minor concern in the grand scheme of "sustaining life on space stations and other planets".
Useless.
Long live the BSD license
http://lmgtfy.com/?q=nasa+research+paper
zosxavius photography
They need to focus on the proper G-spot
Your money's gone.... move along, nothing to see here.
where can I find results of all those experiments?
You better clear out your calendar, you have a lot reading ahead of you.
Hush, we're trying to be bitter about NASA here if you don't mind..
// MD_Update(&m,buf,j);
Astro-Glide!
I don't respond to AC's.
Did anyone else think the headline was a lead-in for Defying Gravity (one of the best sci-fi dramas since Battlestar Galactica)?
Universe series season 3 episode 4 takes a look at this topic. Was made in 2007.
Well, are you prepared to review hot, steamy monkey sex?
Table-ized A.I.
Now we know the answer to a very recent, pertinent question: "how is babby formed?"
My sig is better than your sig.
It's okay, I'll just adopt a baby in space instead. Space is so over populated I don't feel like I should be contributing to it.
Divide a cake by zero. Is it still a cake?
These types of questions could be answered by comparing micro-gravity to artifial gravity. Unfortunately, the ISS module designed to do just that was cancelled
Dear NASA,
I don't believe you. Here's $20 on you being wrong. I will fly up into space and demonstrate for you.
Do we have a bet?
PS - To make sure there are no confounds, please send up hot female astronauts to eliminate alternate explanations on why the experiment failed.
EvilCON - Made Famous by
...Larry Niven predicted this years ago.
In his Known Space universe, the true separation of space-based ("Belter") culture from Earth-based ("Flatlander") culture occurred when the Belters completed their massive 'terraforming' of the inside of an asteroid named Sanctuary as a shelter and home for pregnant Belter women. Rotating the asteroid up to 1-g, they eliminated their last unwanted ties to Earth as women no longer needed to return to the home planet for the period of gestation and birth.
Though, if I remember correctly, Larry Niven's justification for the need was a bit different, as he reasoned that a human fetus brought to term in very low gravity would grow to a size that endangered the life of the mother... I think.
>> Standing on head makes smile of frown, but rest of face also upside down.
PS - To make sure there are no confounds, please send up hot female astronauts to eliminate alternate explanations on why the experiment failed.
Nice try, but there's a glaring omission: you yourself might be someone whose looks alone give reason for a Darwin award.. :-)
Insert
Because storks can't fly in space.
Surely I'm not the only person who looked at this and thought that THIS MIGHT BE THE GREATEST FORM OF CONTRACEPTION EVER INVENTED.
For years science fiction writers have speculated on the adult pleasures that might be enjoyed in zero-gravity. And to find out that it comes with its own natural non-invasive temporary contraceptive?
"Awesome" might be an apt word to describe it. Suddenly space hotels can't come soon enough.
Humph, cell division...When I first saw the headline I thought it was going to be about leverage.
As if making babies in the basement is such an easy task, you insensitive clod!
Catalin Braescu
Ofaly.com
You are saying having a G-force spread in all directions is harmful in a way that zero-G wouldn't be. That makes sense for chicken-eggs in gently rotating glass blenders, but not for the embryonic cells within gently rotating chicken-eggs:
Imagine you're at the center of a giant plastic ball full of water. You have to tell whether or not you're in zero-G.
If the ball was sitting on the surface of the earth you might sink or float to the top, and you'd know right away you're not in zero-G.
Now imagine the ball is being rotated so that you don't sink in any direction (or you sink equally in every direction, if you prefer). As long as the fluid you're in is viscous enough and you are around the same density you couldn't tell whether you were in orbit or on earth.
Of course if you had a handful of uranium pellets you could drop them and they'd fall straight through the water; it only works as a decent zero-G analogue if everything inside was of the same density and/or the liquid is viscous enough to slow the fall in any direction.
On the scale of an embryonic cell there are no uranium pellets, the DNA in your cells isn't lying on the "floor" of the cell after all, and because on a microscopic scale water would seem a lot "thicker" it'd be like falling through syrup for a cell's organic molecules.
If the direction of gravity is changing fast enough from gentle rotation it'd be hard for the cell to "know" whether it was in zero-G or not.
tl;dr: If it's either you or the team of scientists who have had a "logic fail" it's probably going to be you..
// MD_Update(&m,buf,j);
...when there will be people looking down on members of the 10000-metre club. Pun intended.
Hey, baby, I got yer three-dimensional clinostat sperm storage device right here.
I've calculated my velocity with such exquisite precision that I have no idea where I am.
Human pregnancy is different from mice pregnancy. As pregnant woman stands up, gravity aids by pushing baby downwards. This has vital role readying mother for upcoming birth.
The only time childbirth in space would be required/permitted is on some sort of generational mission, right? In that case you're going to need some type of artificial gravity anyway, like the good old fashioned rotating wheel.
If cells don't divide so easily in microgravity ... I see a massively profitable industry of space-therapy opening up in the (probably far, far) future.
G (universal gravitational constant) is everywhere, and no different on earth or in deep space. g (acceleration due to gravity at earths surface) is earth specific.
It is good to see some serious thought and discussion about it.
It would be nice to see some serious data first. The article is based on rotating the cells on the Earth using the stupid assertion that this is somehow the same as no gravity. This is exactly the same as saying that shaking something vigorously is the same as leaving it alone: in both cases the net acceleration is zero. If you try that with a mixture of oil and water the outcome will hardly be the same will it? So why should we expect it to be the same for dividing cells?
i can't find what i want to .may be you should change the pages http:www.dvdorderstore.com
All you need for zero gravitation field (in the Newtonian view) is for the fields to cancel. For example exactly half way between the line joining the centres of two perfact, massive spheres the gravitational field will be zero. Speaking as a physicist I do not see why is this particularly interesting.
Those little guys had no trouble at all!
If you are outside the atmosphere, and not accelerating then you're basically in free fall.
Err no. If you are in freefall then you ARE accelerating be the very definition of what freefall means. If you let go of a ball it will accelerate downwards and it is in freefall. Freefall means that you are free to fall i.e. that only force acting on you is gravity and so the force of gravity will cause you to accelerate.
Sure, gravity is pulling you somewhere, but it doesn't really have an effect on anything inside the spacecraft (your reference frame is moving with you).
Hang on a minute. How can you possibly say that gravity is pulling you somewhere and at the same time claim that it is not affecting anything inside the spacecraft? What do you think is causing things inside the spacecraft to accelerate then? By definition your reference frame is ALWAYS moving with you even if when your surroundings are not. What gravity does is make this an accelerating reference frame instead of an inertial reference frame and the two are most definitely NOT the same.The equivalence between gravity and acceleration is one of the core concepts of GR.
From a biological perspective there is no discernible effect due to gravity.
Yes there is. The reason that your organism is accelerating towards the centre of the planet is an easily measurable effect. In both the case of freefall and sitting on the surface of the planet there are discernable effects due to gravity. In the first case you are accelerating and in the second case you are not accelerating because there is a reaction force between you and the surface of the planet equal and opposite to your weight. In the latter case your internal structure must transmit this normal force throughout your body to cancel your weight in order to prevent all parts of you from accelerating but in both cases the force of gravity acts on all parts of you to the same degree (assuming the same field strength).
This is the same as taking a lift. When the lift accelerates down it does not mean that gravity has suddenly become less it just means that your body has a reduced normal force to distribute because you have a small, downwards acceleration.
As soon as you are in free fall, you're not affected by gravity (at least not in a significant way).
Then could you please explain why you are accelerating downwards? Hint: it is due to a force called GRAVITY. Freefall is when the ONLY force that acts on you is gravity. Under normal circumstances there are two forces which act on you: gravity and a reaction force between you and whatever you are sitting, standing, lying etc. on. In freefall you remove this normal force NOT gravity.
How is babby formed?
-- Cheers!
If you heart is not weighed down by gravity... you may develop arrhythmia?
They carried out reproduction in space of sea urchins, fish, amphibians and birds, but no mice? If I were to study the effects of microgravity on pregnancy, I would put something similar to humans (at least a mammal) at the top of my list, instead of first trying a whole list of species that don't really resemble us. Why use centifuges to "simulate" zero G (?!) and not just send a few mice up to the ISS? OK, it might be difficult to get them to actually reproduce, maybe put them on a 1G centrifuge for the actual copulation bit and then let them float again.
Dear NASA
I for one wish to volunteer for this dangerous experiment to determine whether copulation is possible in a zero-g environment and whether a viable embryo can be formed.
Qualifications:
I have extensive experience with the ZERO sex protocol, so therefore am a perfect candidate for the upgraded ZERO-G sexual encounter.
Thank you for your time
P.S. Please send the mother of the first person to post a smart-arsed reply as one of the female candidates on the mission.
I am not stubborn. I am right!
If you are outside the atmosphere, and not accelerating then you're basically in free fall.
Err no. If you are in freefall then you ARE accelerating be the very definition of what freefall means. If you let go of a ball it will accelerate downwards and it is in freefall. Freefall means that you are free to fall i.e. that only force acting on you is gravity and so the force of gravity will cause you to accelerate.
Sure, gravity is pulling you somewhere, but it doesn't really have an effect on anything inside the spacecraft (your reference frame is moving with you).
Hang on a minute. How can you possibly say that gravity is pulling you somewhere and at the same time claim that it is not affecting anything inside the spacecraft?
Orbit is just freefall around an object due to gravity. Yes, gravity acts on everything in the spacecraft, but not _relative_ to the spacecraft. Maybe English is not your primary language?
This is no more a simulation of no gravity its simply telling you that mice don't do well in rolling barrel.
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The subject line was weeded out. it should have said Gravity from every direction (not equal sign) aka not equal to no gravity at all.
www.Migrainesoft.com - Computer giving you a headache? We can fix that!
I long for the day that gravity is controlled by a switch, like the lights of a room...
what would the effect be of higher gravity on development?
Any women out there want to spend 9 months in a centrifuge?
Maybe snuggies could help?
http://thesnuggiesutra.com/
Jason: The real point is not to get yourself into this position, that's what you have to realize. You gotta know all the tricks like, for example, if a woman's on top she can't get pregnant. It's just gravity.
Jonah: Well that's true. Everyone knows that.
Jason: What goes up must come down.
I really hate that expression. If there were no gravity "in space", the International Space Station, as well as GPS and communications satellites, wouldn't stay in orbit. For that matter, the moon wouldn't orbit the Earth, and the Earth wouldn't orbit the Sun. The correct term is "free fall".
[100% ISO 646 Compliant]
SVM, ERGO MONSTRO.
My mother is dead, you insensitive clod!
[100% ISO 646 Compliant]
SVM, ERGO MONSTRO.
Put the mom (natural or artificial) in a calibrated centrifuge so that it provides a force akin to gravity.
NO SIG
Yes.
I realize that this is a risky assignment; but, in the name of science I will volunteer to undergo the rigors of space-sex again and again and again until we have a pregnancy or I will die trying, so help me God!
"Mrs. Krabappel and Principal Skinner were in the capsule making Starbabies and I saw one of the Starbabies and then the Starbaby looked at me."
Mod Karma -1: I sed bad wurds. If I cep my mouf shut, I wud be at riyses.
I want my space baby now!
An Alien face-hugger seems to do fairly well in both induced gravity and near-/zero-gravity environments.
When i saw the title, I knew 2 things: 1. The content of the post would probably disappoint me. 2. The content of the comments probably wouldn't. I win!
Diagram says:
This reminds me of the episode of DS9 where Odo finds an 'infant' shape-shifter. He tries teaching the thing to shape-shift by pouring the goo into different shaped containers...and fails. What finally inspires the little sentient goo-goo child to form a shape? Electric shock.
So our cells require the hardship of gravity to mature...poetical wisdom.
What about bunnies? Rufus is going to die, isn't he?
Shop as usual. And avoid panic buying.
The clinostat bit is still somewhat puzzling. One would have thought that with all the junk they drag back and forth between earth and the space station they would have included a couple of pregnant mice by now. Anybody know why this is so?
Not at all - it would know because of the pressure difference across the cell would always be changing direction.
The other guy who responded added this point, but I think he was right that it'd have a negligible effect for embryos, which are tiny.
Ah - but here is the crux of the matter. You are arguing on one hand that the pressure difference across the cell is a "negligible" but the only difference between zero-g and being on the surface of the earth is this pressure difference. So either you are correct and it is negligible - in which case the results are wrong - or it is not negligible and therefore you cannot neglect the effect of varying it and so the results are potentially wrong.
The problem is not fertilization but growth. In the 60's "apical meristem" propagation of orchids, trees and other plants became common. The growing end of a plant is dissected deposite in a nutrient broth then placed in a tumbling rack so the plant could not discover "up". The dissected bit would still grow and after a week it was chopped into bits which were then tumbled for a week or so. In almost no time thousands of identical clones would be tumbling. The next step was to deposit them on a solid nutrient rich gel and after they began to display a couple leaves they would be moved out of the sterile jars into flats. At this point the roll of beneficial was discovered but that is another not so trifling (truffeling too) subject
Truth is stranger than fiction, but it is because Fiction is obliged to stick to possibilities; Truth isn't. Mark Twain.