Domain: bmj.com
Stories and comments across the archive that link to bmj.com.
Stories · 45
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Screen Time Not Intrinsically Bad For Children, Say Doctors (theguardian.com)
Spending time looking at screens is not intrinsically bad for children's health, say the UK's leading children's doctors, who are advising parents to focus on ensuring their children get enough sleep, exercise and family interaction rather than clamping down on phones and laptops. From a report: The Royal College of Paediatrics and Child Health has produced the first guidance for parents on how long children should spend on their laptops and phones, which throws the ball firmly back into the parents' court. Each family should decide what is best for its own members -- although all children would benefit from switching off the screen an hour before they go to bed to help them sleep. The college says the focus for parents should be on what the family is doing together, saying screen time is not an issue if parents have control over other aspects of their children's lives. The guidance appears to run counter to the thinking of the health secretary, Matt Hancock, a father of three young children, who has asked England's chief medical officer, Dame Sally Davies, to draw up some rules on the use of social media. -
Researchers Show Parachutes Don't Work, But There's A Catch (npr.org)
Reader Beeftopia shares a report: Research published in a major medical journal concludes that a parachute is no more effective than an empty backpack at protecting you from harm if you have to jump from an aircraft. But before you leap to any rash conclusions, you had better hear the whole story. The gold standard for medical research is a study that randomly assigns volunteers to try an intervention or to go without one and be part of a control group. For some reason, nobody has ever done a randomized controlled trial of parachutes. In fact, medical researchers often use the parachute example when they argue they don't need to do a study because they're so sure they already know something works. Cardiologist Robert Yeh, an associate professor at Harvard Medical School and attending physician at Beth Israel Deaconess Medical Center, got a wicked idea one day. He and his colleagues would actually attempt the parachute study to make a few choice points about the potential pitfalls of research shortcuts.
They started by talking to their seatmates on airliners. [...] In all, 23 people agreed to be randomly given either a backpack or a parachute and then to jump from a biplane on Martha's Vineyard in Massachusetts or from a helicopter in Michigan. Relying on two locations and only two kinds of aircraft gave the researchers quite a skewed sample. But this sort of problem crops up frequently in studies, which was part of the point Yeh and his team were trying to make. Still, photos taken during the experiment show the volunteers were only too happy to take part. The drop in the study was about 2 feet total, because the biplane and helicopter were parked. Nobody suffered any injuries. Surprise, surprise. So it's technically true that parachutes offered no better protection for these jumpers than the backpacks. -
Are Touchscreens Robbing a Generation of Surgeons of Their Dexterity? (bbc.com)
schwit1 shared this article from the BBC: A professor of surgery says students have spent so much time in front of screens and so little time using their hands that they have lost the dexterity for stitching or sewing up patients. Roger Kneebone, professor of surgical education at Imperial College, London, says young people have so little experience of craft skills that they struggle with anything practical. "It is important and an increasingly urgent issue," says Prof Kneebone, who warns medical students might have high academic grades but cannot cut or sew. "It is a concern of mine and my scientific colleagues that whereas in the past you could make the assumption that students would leave school able to do certain practical things - cutting things out, making things - that is no longer the case," says Prof Kneebone.
The professor, who teaches surgery to medical students, says young people need to have a more rounded education, including creative and artistic subjects, where they learn to use their hands. Prof Kneebone says he has seen a decline in the manual dexterity of students over the past decade - which he says is a problem for surgeons, who need craftsmanship as well as academic knowledge.... "A lot of things are reduced to swiping on a two-dimensional flat screen," he says, which he argues takes away the experience of handling materials and developing physical skills. Such skills might once have been gained at school or at home, whether in cutting textiles, measuring ingredients, repairing something that's broken, learning woodwork or holding an instrument. Students have become "less competent and less confident" in using their hands, he says. "We have students who have very high exam grades but lack tactile general knowledge," says the professor.
Interestingly, much of the professor's research is on simulations, according to his web page at Imperial College London, where he leads "an unorthodox and creative research group" that uses professional actors with inanimate models to create realistic clinical encounters, as well as "low-cost, portable yet highly convincing environments such as the 'inflatable operating theatre'." -
Vaping Can Damage Vital Immune System Cells, Researchers Find (bbc.co.uk)
Vaping can damage vital immune system cells and may be more harmful than previously thought, a study suggests. Researchers found e-cigarette vapour disabled important immune cells in the lung and boosted inflammation. From a report: The researchers "caution against the widely held opinion that e-cigarettes are safe." However, Public Health England advises they are much less harmful than smoking and people should not hesitate to use them as an aid to giving up cigarettes. The small experimental study, led by Prof David Thickett, at the University of Birmingham, is published online in the journal Thorax. Previous studies have focused on the chemical composition of e-cigarette liquid before it is vaped. In this study, the researchers devised a mechanical procedure to mimic vaping in the laboratory, using lung tissue samples provided by eight non-smokers. They found vapour caused inflammation and impaired the activity of alveolar macrophages, cells that remove potentially damaging dust particles, bacteria and allergens. -
Can Two Injections of Tuberculosis Vaccine Cure Diabetes? (fortune.com)
An anonymous reader quotes Fortune: The causes of Type 1 diabetes can be significantly reversed over several years with just two injections of a common tuberculosis vaccine injected a few weeks apart, researchers at Massachusetts General Hospital announced Thursday in a paper published in the journal Nature. Researchers found a substantial reduction in the blood-sugar marker HbA1c that is used to diagnose diabetes.
All subjects with diabetes who received the vaccine had a 10% reduction after three years and 18% after four years, bringing them below the cutoff point for a clinical diagnosis. Those subjects followed for a full eight years retained most of the reduction. Participants who received a placebo or were in a reference group that followed normal diabetic management saw their blood sugar measurement rise by a few percentage points during the same periods followed... A 10% reduction in Hb1Ac reduces the risk of death as a result of diabetes by 21%, and drops by 37% other complications, like blindness and loss of feeling in hands and feet, according to a 2000 study. -
Scientists Find Physically Demanding Jobs Are Linked To Greater Risk of Early Death (metro.co.uk)
An anonymous reader quotes a report from Metro: Researchers in the Netherlands claim that a "physical activity paradox" exists, where exercise may only be good for you if it's done outside of your job. Manual laborers may be physically active all day but that doesn't actually help them. In fact, the research claims that it might actually increase their risk of dying early. "While we know leisure-time physical activity is good for you, we found that occupational physical activity has an 18% increased risk of early mortality for men," says Pieter Coenen, public health researcher at UV University medical centre in Amsterdam. "These men are dying earlier than those who are not physically active in their occupation."
He says that it's all down to the type of exercise you do in your spare time, versus occupational physical activity. When you choose to exercise, you can take rest periods when you want -- something that often may not be available to you if you're working on a building site (for example). The research combined results from 17 studies, dated between 1960 and 2010 -- looking at data on almost 200,000 people. The study has been published in the British Journal of Sports Medicine. -
Eating World's Hottest Pepper Sparks Brain Disorder, Thunderclap Headaches (arstechnica.com)
An anonymous reader quotes a report from Ars Technica: Extremely hot peppers don't just blister your mouth and bum -- they can also spark fiery havoc in your brain, according to a report published Monday in BMJ Case Reports. An otherwise healthy 34-year-old man developed a blood-flow disorder in his brain and suffered several debilitating "thunderclap" headaches after entering a hot pepper eating contest, U.S. doctors reported. The man had managed to get down a Carolina Reaper pepper, which in 2013 earned the title of the world's hottest chili by Guinness World Records.
The searing pepper didn't sit well in the chili-eating contestant. Immediately after slaying a Reaper, the man began dry heaving and developed pain in his neck and the back of his skull. That morphed into a diffuse, painful headache. Over the next few days, he experienced thunderclap headaches at least twice -- but likely more, he just couldn't recall exactly. Thunderclap headaches are severe, sudden, with quick pains that strike like a clap of thunder rumbling through your skull. They tend to peak within 60 seconds and can be accompanied by nausea, vomiting, altered mental state, seizures, and fever. Their stormy aches can be a sign of serious problems, like bleeding in the brain, a brain infection, or a cerebrospinal fluid leak. The pain was excruciating enough that the man went to the emergency room. But doctors didn't find any immediate problems with him to explain the episodes. He didn't have any slurred speech, loss of vision, neurological deficits, muscle weakness, or tingling. His blood pressure was a little high, but not extremely so, at 134/69 mmHg. Initial CT scans found no problems in his neck and head. -
Ultra-Processed Foods May Be Linked To Cancer, Says Study (theguardian.com)
An anonymous reader quotes a report from The Guardian: Ultra-processed" foods, made in factories with ingredients unknown to the domestic kitchen, may be linked to cancer, according to a large and groundbreaking study. Ultra-processed foods include pot noodles, shelf-stable ready meals, cakes and confectionery which contain long lists of additives, preservatives, flavorings and colorings -- as well as often high levels of sugar, fat and salt. They now account for half of all the food bought by families eating at home in the UK, as the Guardian recently revealed. A team, led by researchers based at the Sorbonne in Paris, looked at the medical records and eating habits of nearly 105,000 adults who are part of the French NutriNet-Sante cohort study, registering their usual intake of 3,300 different food items. They found that a 10% increase in the amount of ultra-processed foods in the diet was linked to a 12% increase in cancers of some kind. The researchers also looked to see whether there were increases in specific types of cancer and found a rise of 11% in breast cancer, although no significant upturn in colorectal or prostate cancer. "If confirmed in other populations and settings, these results suggest that the rapidly increasing consumption of ultra-processed foods may drive an increasing burden of cancer in the next decades," says the paper in the British Medical Journal. -
Why You Shouldn't Stifle Your Sneeze (theguardian.com)
An anonymous reader quotes a report from The Guardian: In a season where colds are rife, holding your nose and closing your mouth might seem like a considerate alternative to an explosive "Achoo!" But doctors have warned of the dangers of such a move after a man was found to have ruptured the back of his throat when attempting to stifle a sneeze. Medics say the incident, which they detail in the British Medical Journal Case Reports, came to light when a 34-year old man arrived in A&E with a change to his voice, a swollen neck, pain when swallowing and a popping sensation in his neck after he pinched his nose to contain an expulsion. The team took scans of the man's neck to investigate and discovered bubbles of air in the tissues at the back of the throat, and in the neck from the base of the skull to halfway down the man's back. That, they say, suggested a tear had occurred at the back of the throat as a result of increased pressure from the stifled sneeze, leading to air collecting in his soft tissues. The authors warn that blocking the nostrils and mouth when sneezing is dangerous, noting that while tearing of the throat tissue is rare, it could result in a ruptured eardrum or even a brain aneurysm. -
Study Finds Different Types of Alcohol Can Determine Different Moods (bbc.com)
A new study published in the journal BMJ Open says different types of alcoholic drinks change and shape your mood in different ways. For example, spirits may make you feel angry, sexy or tearful, while red wine or beer may make you feel relaxed. The researchers questioned nearly 30,000 people aged 18-34 from 21 different countries for the study. BBC reports: The anonymous online survey, which recruited respondents via newspaper and magazine adverts and social media, found:
-Red wine appeared to make people more lethargic than white wine
-Respondents were most likely to report feeling relaxed when drinking red wine or beer
-More than 40% said drinking spirits made them feel sexy
-Over half said drinking spirits also gave them energy and confidence
-But around a third said they felt aggressive when drinking spirits
-Drinking spirits was more likely than all other drink types to be associated with feelings of aggression, illness, restlessness and tearfulness
-Men were significantly more likely than women to associate feelings of aggression with all types of alcohol, particularly heavier drinkers
Prof Bellis from Public Health Wales NHS Trust said the setting in which the alcohol was consumed was an important factor that the study tried to take into consideration by asking about drinking at home and outside of the home. He said the way different drinks are marketed and promoted might encourage people to select certain drinks to suit different moods, but that this could backfire if it triggered negative emotions. He also said the study revealed a difference between men and women's emotional relationship with different alcoholic drinks. -
Over Half of New Cancer Drugs 'Show No Benefits' For Survival Or Wellbeing (theguardian.com)
New research published in the British Medical Journal finds that most cancer drugs that have recently arrived on the market have come with little evidence that they boost the survival or wellbeing of patients. The Guardian reports: Forty-eight cancer drugs were approved by the European Medicines Agency between 2009 and 2013 for use as treatments in 68 different situations. But the study, which looked at the clinical trials associated with the drugs, reveals that at the time the therapies became available there was no conclusive evidence that they improved survival in almost two-thirds of the situations for which they were approved. In only 10% of the uses did the drugs improve quality of life. Overall 57% of uses showed no benefits for either survival or quality of life. The team then looked to see whether the picture improved over time. The team found that after a follow-up period of between three to eight years, 49% of approved uses were linked to no clear sign of improvement in survival or quality of life. Where survival benefits were shown, the team said these were clinically meaningless in almost half of the cases. -
2017 'Ig Nobel' Prizes Recognize Funny Research On Cats, Crocodiles, and Cheese (improbable.com)
An anonymous reader writes: "The 27th First Annual Ig Nobel Prize Ceremony" happened Thursday at Harvard's Sanders theatre, recognizing real (but unusual) research papers from all over the world "that make people laugh, then think." This year's prize in the physics category went to Marc-Antoine Fardin, who used fluid dynamics to probe the question "Can a cat be both a solid and a liquid?"
Six prize-winning Swiss researchers also demonstrated that regular playing of a didgeridoo is an effective treatment for obstructive sleep apnoea and snoring, while two Australians tested how contact with a live crocodile affects a person's willingness to gamble. And five French researchers won the medicine prize for their use of advanced brain-scanning technology to investigate "the neural basis of disugst for cheese."
You can watch the ceremony online -- and Reuters got an interesting quote from the editor of the Annals of Improbable Research, who founded the awards ceremony 27 years ago. "We hope that this will get people back into the habits they probably had when they were kids of paying attention to odd things and holding out for a moment and deciding whether they are good or bad only after they have a chance to think." -
E-Cigarettes Linked To Helping People Quit Smoking, Says Study (theverge.com)
According to a new study, electronic cigarettes help people trying to quit smoking. The Verge reports: For the study, published today in the journal BMJ, researchers analyzed survey data from over 160,000 people spanning almost 15 years. They found that smokers who used e-cigs tried to quit smoking more often and succeeded (for at least three months) more often than smokers who didn't use e-cigs. Overall, more people quit in the latest year that data was available -- the 2014 -- 15 year -- than in the 2010 -- 11 year. Today's study didn't address whether e-cigs are luring people who would otherwise be nonsmokers. But it did find that e-cigs do have a role in helping people quit. The researchers looked at several population surveys that cover the years 2001 to 2015. These surveys provided smoking-cessation rates, and the most recent survey, from 2014 to 2015, had information about e-cigarette usage. The results show that 65 percent of e-cigarette users had tried to quit smoking, versus 40 percent of people who smoked but didn't use e-cigs. About 8 percent of e-cig users succeeded in quitting for at least three months, compared to about 5 percent of non-users. Overall, the number of people who quit smoking increased by 1.1 percentage points in 2015 from 2011. This might not seem that impressive, but it still represents about 350,000 people. -
Moderate Drinking Can Damage the Brain, Claim Researchers (theguardian.com)
An anonymous reader quotes a report from The Guardian: Drinking even moderate amounts of alcohol can damage the brain and impair cognitive function over time, researchers have claimed. Writing in the British Medical Journal, researchers from the University of Oxford and University College London, describe how they followed the alcohol intake and cognitive performance of 550 men and women over 30 years from 1985. At the end of the study the team took MRI scans of the participants' brains. None of the participants were deemed to have an alcohol dependence, but levels of drinking varied. After excluding 23 participants due to gaps in data or other issues, the team looked at participants' alcohol intake as well as their performance on various cognitive tasks, as measured at six points over the 30 year period. The team also looked at the structure of the participants' brains, as shown by the MRI scan, including the structure of the white matter and the state of the hippocampus -- a seahorse-shaped area of the brain associated with memory. After taking into account a host of other factors including age, sex, social activity and education, the team found that those who reported higher levels of drinking were more often found to have a shrunken hippocampus, with the effect greater for the right side of the brain. While 35% of those who didn't drink were found to have shrinkage on the right side of the hippocampus, the figure was 65% for those who drank on average between 14 and 21 units a week, and 77% for those who drank 30 or more units a week. -
The Older the Doctor, the Higher the Patient Mortality Rate, Study Finds (arstechnica.com)
An anonymous reader quotes a report from Ars Technica: The age of your doctor may impact the quality of the care you receive -- and even cut your chances of survival -- researchers report in the British Medical Journal. Harvard researchers looked over data on more than 700,000 hospital admissions of elderly patients cared for by nearly 19,000 physicians between 2011 and 2014. They found that mortality rates crept up in step with physician age. Patients with doctors under the age of 40 had a 30-day mortality rate of 10.8 percent. With doctors aged 40 to 49, mortality rates inched up to 11.1 percent, then to 11.3 percent with doctors 50 to 59, and 12.1 percent with doctors aged 60 or above. The stats are adjusted for a variety of variables, such as hospital mortality rates and severity of patients' illnesses. All the patients were aged 65 or older and on Medicare. Though the age-related mortality trend was significant overall, it broke down when researchers sorted doctors by caseloads. Older doctors who saw high volumes of patients didn't see their patients' mortality rates increase. -
Cycling To Work Can Cut Cancer and Heart Disease (bbc.com)
randomErr quotes a report from BBC: Want to live longer? Reduce your risk of cancer? And heart disease? Then cycle to work, say scientists. The five-year study of 250,000 UK commuters also showed walking had some benefits over sitting on public transport or taking the car. Published in the British Medical Journal (BMJ) today, the University of Glasgow study compared those who had an "active" commute with those who were mostly stationary. Overall, 2,430 of those studied died, 3,748 were diagnosed with cancer and 1,110 had heart problems. But, during the course of the study, regular cycling cut the risk of death from any cause by 41%, the incidence of cancer by 45% and heart disease by 46%. The cyclists clocked an average of 30 miles per week, but the further they cycled the greater the health boon. However, the effect was still there even after adjusting the statistics to remove the effects of other potential explanations like smoking, diet or how heavy people are. -
Parenthood Can Help You Live Longer In Older Age, Research Suggests (theguardian.com)
An anonymous reader quotes a report from The Guardian: Parenthood could boost your chances of living longer in your later years, according researchers who believe the effect could be down to children helping with care and support. While previous research has shown that adults with children live longer than those without, the new study unpicks how the effect plays out in older age. Modig and colleagues used national registry data to follow almost 1.5 million Swedes born between 1911 and 1925 as they aged. The team found that while the risk of death increased with age for all adults, having children was linked to greater longevity. The results are published in the Journal of Epidemiology and Community Health. At the age of 60, men who had children had almost two years more on their remaining life expectancy than those without, at 20.2 and 18.4 years respectively. A similar trend was seen for women aged 60, with life expectancies of 23.1 years for those without children and 24.6 years for mothers. By contrast at the age of 80, parents had a life expectancy of 7.7 years for men and 9.5 years for women, compared to 7 years for men without children and 8.9 years for women without children. The findings reveal that the benefits of having children became more pronounced with age -- an effect that was greater for men than women. Furthermore, the team found that having children had a stronger impact on the longevity of men who were not married than those with a spouse. -
How Social Isolation Is Killing Us (nymag.com)
schwit1 quotes a report from The New York Times: Social isolation is a growing epidemic (Warning: may be paywalled; alternate source) -- one that's increasingly recognized as having dire physical, mental and emotional consequences. Since the 1980s, the percentage of American adults who say they're lonely has doubled from 20 percent to 40 percent. About one-third of Americans older than 65 now live alone, and half of those over 85 do. People in poorer health -- especially those with mood disorders like anxiety and depression -- are more likely to feel lonely. Those without a college education are the least likely to have someone they can talk to about important personal matters. A wave of new research suggests social separation is bad for us. Individuals with less social connection have disrupted sleep patterns, altered immune systems, more inflammation and higher levels of stress hormones. One recent study found that isolation increases the risk of heart disease by 29 percent and stroke by 32 percent. Another analysis that pooled data from 70 studies and 3.4 million people found that socially isolated individuals had a 30 percent higher risk of dying in the next seven years, and that this effect was largest in middle age. Loneliness can accelerate cognitive decline in older adults, and isolated individuals are twice as likely to die prematurely as those with more robust social interactions. These effects start early: Socially isolated children have significantly poorer health 20 years later, even after controlling for other factors. All told, loneliness is as important a risk factor for early death as obesity and smoking. -
Medical Errors Are Number 3 Cause of US Deaths, Researchers Say (npr.org)
An anonymous reader quotes a report from NPR: A study by researchers at Johns Hopkins Medicine says medical errors should rank as the third-leading cause of death in the United States -- and highlights how shortcomings in tracking vital statistics may hinder research and keep the problem out of the public eye. The authors, led by Johns Hopkins surgeon Dr. Martin Makary, call for changes in death certificates to better tabulate fatal lapses in care. In an open letter, they urge the Centers for Disease Control and Prevention to immediately add medical errors to its annual list reporting the top causes of death. Based on an analysis of prior research, the Johns Hopkins study estimates that more than 250,000 Americans die each year from medical errors. On the CDC's official list, that would rank just behind heart disease and cancer, which each took about 600,000 lives in 2014, and in front of respiratory disease, which caused about 150,000 deaths. Medical mistakes that can lead to death range from surgical complications that go unrecognized to mix-ups with the doses or types of medications patients receive. The study was published Tuesday in The BMJ, formerly the British Medical Journal. -
City Installs Traffic Lights In Sidewalks For Smartphone Users (washingtonpost.com)
tlhIngan writes: It's finally happened -- the smartphone zombies are here. The German city of Augsburg installed traffic lights in the sidewalks so smartphone users don't have to look up. Apparently people are so addicted to their smartphones they can't be bothered to look up at traffic signals, so embedding them in the ground they don't have to. According to the Washington Post report, the city spokeswoman Stephanie Lermen thinks the money used to install the lights is well spent. A recent survey conducted in several European cities including Berlin, found that almost 20 percent of pedestrians were distracted by their smartphones. Of course, younger people are at higher risk as they're willing to risk their safety to look at their Facebook profiles or WhatsApp messages, the survey found. The problem may be even worse in the U.S: A survey by the University of Washington found that 1 in 3 Americans is busy texting or working on a smartphone at dangerous road crossings. City officials say installing the traffic lights is justified: The idea is to install such traffic lights came after a 15-year-old girl was killed by a tram. According to police reports, she was distracted by her smartphone as she crossed the tracks. -
Replacing Butter With Vegetable Oils Doesn't Decrease Risk of Heart Disease, Says Study (medicalxpress.com)
An anonymous reader writes: A research team led by scientists at the UNC School of Medicine and the National Institutes of Health has unearthed more evidence that casts doubt on the traditional "heart healthy" practice of replacing butter and other saturated fats with corn oil and other vegetable oils high in linoleic acid. The findings, reported today in the British Medical Journal, suggest that using vegetable oils high in linoleic acid might be worse than using butter when it comes to preventing heart disease, though more research needs to be done on that front. This latest evidence comes from an analysis of previously unpublished data of a large controlled trial conducted in Minnesota nearly 50 years ago, as well as a broader analysis of published data from all similar trials of this dietary intervention. The analyses show that interventions using linoleic acid-rich oils failed to reduce heart disease and overall mortality even though the intervention reduced cholesterol levels. In the Minnesota study, participants who had greater reduction in serum cholesterol had higher rather than lower risk of death. Two things to note about the study: 75% of the participants left in less than a year (perhaps not uncommon, the study doesn't explain why these people left); the vegetable oils mentioned in the article are not necessarily the most commonly used (which are oils made of olive, sunflower, coconut, and palm). -
Fruit Drinks Aren't Much Better For You Than Soda: Study (vox.com)
An anonymous reader cites a study on Vox: One of the biggest public health wins of recent decades has been America's slow shift away from soda. But there's pretty good evidence that Americans are still getting hoodwinked by juices and other sugary beverages. Data from Euromonitor, which analyzed U.S. retail beverage sales over the past five years, shows that while the soda category is shrinking, juice sales have held steady, and sales of energy and sports drinks have been growing. An article in BMJ Open demonstrates the extent of the problem: The researchers looked at how much of the American diet is composed of ultra-processed foods and added sugars. They found that 58 percent of total energy intake -- more than half of the calories Americans consume! -- came from foods that are packed with lots of flavors, colors, and sweeteners. And almost 90 percent of the added sugars Americans consume came from heavily processed foods -- the two main sources being soft drinks (17 percent) closely followed by fruit drinks (14 percent). (In this case, 'fruit drinks' refers to processed juices with added sugars.) -
Re-Analysis of Medical Study Reverses Conclusions -- Paxil Unsafe For Teenagers
An anonymous reader writes: The NY Times is covering a new paper in the journal BMJ which re-analyzed data from a 2001 paper, coming to the opposite conclusions of the earlier study. The BMJ paper covers the effectiveness and safety of two antidepressant drugs for adolescent use, and the authors were able to re-analyze the original data after the release of previously confidential documents. The BMJ editors call into question some of the integrity of previous publishing, noting that none of the authors listed on 2001 paper actually wrote the original manuscript, and call for results of clinical trials to be made freely available so the science community can verify and self-correct results. The BMJ has released the study and provided an accompanying press release (PDF). -
Re-Analysis of Medical Study Reverses Conclusions -- Paxil Unsafe For Teenagers
An anonymous reader writes: The NY Times is covering a new paper in the journal BMJ which re-analyzed data from a 2001 paper, coming to the opposite conclusions of the earlier study. The BMJ paper covers the effectiveness and safety of two antidepressant drugs for adolescent use, and the authors were able to re-analyze the original data after the release of previously confidential documents. The BMJ editors call into question some of the integrity of previous publishing, noting that none of the authors listed on 2001 paper actually wrote the original manuscript, and call for results of clinical trials to be made freely available so the science community can verify and self-correct results. The BMJ has released the study and provided an accompanying press release (PDF). -
New Nudge Technology Prods You To Take Action
HughPickens.com writes Natasha Singer reports at the NYT on a new generation of devices whose primary function is to prod people to change. This new category of nudging technology includes "hydration reminder" apps like Waterlogged that exhort people to increase their water consumption; the HAPIfork, a utensil that vibrates and turns on a light indicator when people eat too quickly; and Thync, "neurosignaling" headgear that delivers electrical pulses intended to energize or relax people. "There is this dumbing-down, which assumes people do not want the data, they just want the devices to help them," says Natasha Dow Schüll. "It is not really about self-knowledge anymore. It's the nurselike application of technology." While some self-zapping gizmos may resemble human cattle prods, other devices use more complex cues to encourage people to adopt new behavior. For example, the Muse, a brain-wave monitoring headband, is intended to help people understand their state of mind by playing different sounds depending on whether they are distracted or calm. "Based on what it registers, it plays loud, disruptive wind or waves lapping or, if you are supercalm and you maintain it for a while, you get calm, lovely noises of birds tweeting," says Schüll. "You do learn to calm your mind.
But do the new self-tracking and self-improvement technologies benefit people or just create more anxiety? An article published in The BMJ, a British medical journal, describes healthy people who use self-tracking apps as "young, asymptomatic, middle-class neurotics continuously monitoring their vital signs while they sleep." Dr. Des Spence argues that many health tracking apps encouraged healthy people to unnecessarily record their normal activities and vital signs — turning users into continuously self-monitoring "neurotics." Spence recommends people view these new technologies with skepticism. "The truth is that these apps and devices are untested and unscientific, and they will open the door of uncertainty," says Spence. "Make no mistake: Diagnostic uncertainty ignites extreme anxiety in people." -
Ask Slashdot: Why Does Science Appear To Be Getting Things Increasingly Wrong?
azaris writes: Recent revelations of heavily policy-driven or even falsified science have raised concern in the general public, but especially in the scientific community itself. It's not purely a question of political or commercial interference either (as is often claimed when it comes to e.g. climate research) — scientists themselves are increasingly incentivized to game the system for improved career prospects, more funding, or simply because they perceive everyone else to do it, too. Even discounting outright fraud or manipulation of data, the widespread use of methodologies known to be invalid plagues many fields and is leading to an increasing inability to reproduce recent findings (the so-called crisis of reproducibility) that puts the very basis of our reliance on scientific research results at risk. Of course, one could claim that science is by nature self-correcting, but the problem appears to be getting worse before it gets better.
Is it time for more scientists to speak out openly about raising the level of transparency and honesty in their field? -
An Evidence-Based Approach To Online Dating
HughPickens.com writes Rachel Nuwer writes in the NYT that Dr. Sameer Chaudhry's online dating persona was garnering no response from the women he reached out to so he synthesized 86 literature studies on the subject of online dating in the fields of psychology, sociology, and computer, behavioral, and neurocognitive sciences.in hopes of improving his odds. As it turns out, success begins with picking a user name. While men are drawn to names linked to physical traits (e.g., Cutie), the researchers found, women prefer ones that indicate intelligence (e.g., Cultured). Both sexes respond well to playful names (e.g. Fun2bwith) and shy away from ones with negative connotations (e.g., Bugg). User names that begin with letters from the first half of the alphabet do better than those from the latter half. "As human beings, we have a tendency to give things at the top of a pile more value," says Khan. As for your profile photo, pick a photo with a genuine smile, one that crinkles the eyes, and with a slight head tilt (it's linked to attractiveness). And if you're looking for a male partner, go for that photo of you in siren red—a color that enhances men's attraction to women. "For those attracted to browse into the profile, a description of personal traits increased likeability when it: showed who the dater was and what they were looking for in a 70:30 ratio; stayed close to reality; and employed simple language with humor added. Invitations were most successful in obtaining a response from the potential date when they: were short personalized messages addressing a trait in their profile; rhymed with their screen name or headline message; and extended genuine compliments." And finally, don't wait too long before arranging a face to face meeting. -
Alcohol's Evaporating Health Benefits
New submitter Heart44 writes: A study in the British Medical Journal shows that consuming alcohol — any volume, any type — does not increase life expectancy. The full academic paper is not paywalled. From its conclusions: "Beneficial associations between low intensity alcohol consumption and all cause mortality may in part be attributable to inappropriate selection of a referent group and weak adjustment for confounders. Selection biases may also play a part." The associated editorial adds, "Firstly, in health as elsewhere, if something looks too good to be true, it should be treated with great caution. Secondly, health professionals should discourage suggestions that even low level alcohol use protects against cardiovascular disease and brings mortality benefits. Thirdly, health advice should come from health authorities, not from the alcohol industry, and, finally, the alcohol industry and its organizations should remove misleading references to health benefits from their information materials." -
Alcohol's Evaporating Health Benefits
New submitter Heart44 writes: A study in the British Medical Journal shows that consuming alcohol — any volume, any type — does not increase life expectancy. The full academic paper is not paywalled. From its conclusions: "Beneficial associations between low intensity alcohol consumption and all cause mortality may in part be attributable to inappropriate selection of a referent group and weak adjustment for confounders. Selection biases may also play a part." The associated editorial adds, "Firstly, in health as elsewhere, if something looks too good to be true, it should be treated with great caution. Secondly, health professionals should discourage suggestions that even low level alcohol use protects against cardiovascular disease and brings mortality benefits. Thirdly, health advice should come from health authorities, not from the alcohol industry, and, finally, the alcohol industry and its organizations should remove misleading references to health benefits from their information materials." -
Shift Work Dulls Brain Performance
davidshenba writes: Scientists warn that working in unusual shifts can prematurely age the brain and dull intellectual ability. Three thousand people in France were given tests of memory, speed of thought and wider cognitive ability. People with more than 10 years of shift work history had the same results as someone six and a half years older. The brain naturally dulls as we age, but the researchers said working antisocial shifts accelerated the process. -
Farmers Carry Multidrug-Resistant Staph For Weeks Into Local Communities
An anonymous reader writes: Fresh research out of the UNC Gillings and JHU Bloomberg schools of public health shows industrial farm workers are carrying livestock-associated, multidrug-resistant staph into local communities for weeks at a time. "Among the [22 people tested], 10 workers carried antibiotic-resistant strains of the bacteria in their noses for up to four days. Another six workers were intermittent carriers of the bacteria. The 10 workers found to carry the bacteria persistently had strains associated with livestock that were resistant to multiple drugs, and one also carried MRSA. Three more of the workers tested positive for strains of S. aureus that were not resistant to antibiotics. So in total, 86 percent of the workers in the study carried the S. aureus bacteria, compared with about one-third of the population at large, according to the Centers for Disease Control and Prevention." This problem has grown since its last mention on Slashdot. Unfortunately, massive industrial lobbying continues to neuter government action. -
Surgeries On Friday Are More Frequently Fatal
antdude writes "A British Medical Journal (BMJ) research report says that 'Surgeries on Friday Are More Frequently Fatal ... compared to those who opt for really bad Mondays, Britons who have a planned surgery on a Friday are 44 percent more likely to die. And the few patients who had a leisurely weekend surgery saw that number jump to 82 percent. The skeleton staff working on weekends might be to blame.'" -
Drug Company Disguised Advertising As Science
ananyo writes "A former pharmaceutical company employee has blown the whistle on drug promotion disguised as science. Drug companies occasionally conduct post-marketing studies to collect data on the safety and efficacy of drugs in the real world, after they've been approved by the U.S. Food and Drug Administration. 'However,' writes the anonymous author in an editorial in the British Medical Journal (subscription required), 'some of the [post-marketing] studies I worked on were not designed to determine the overall risk:benefit balance of the drug in the general population. They were designed to support and disseminate a marketing message.' According to the whistleblower, the results of these studies were often dubious. 'We occasionally resorted to "playing" with the data that had originally failed to show the expected result,' he says. 'This was done by altering the statistical method until any statistical significance was found.' He adds that the company sometimes omitted negative results and played down harmful side effects. Nature says it was unable to work out who the writer was but they likely worked on diabetes and the studies criticized were from the Denmark-based pharmaceutical company Novo Nordisk." -
Those Sleeping Pills May Be Killing You
dstates writes "A recent article in in BMJ Open reports a strong association between the use of prescription sleeping pills and mortality. The study used electronic health records for 2.5 million people covered by the Geisinger Health System to find 12 thousand who had been prescribed sleeping pills and a matched set of controls. Death rates were much higher in the patients taking sleeping pills and the risk increases with age. Kudos to the authors for publishing this in an open access journal." -
Aging Eyes Blamed For Seniors' Health Woes
Hugh Pickens writes "Scientists have looked for explanations as to why certain conditions occur with age, among them memory loss, slower reaction time, insomnia and even depression looking at such suspects as high cholesterol, obesity, heart disease and an inactive lifestyle. Now Laurie Tarkan writes that as eyes age, less and less sunlight gets through the lens to reach key cells in the retina that regulate the body's circadian rhythm, its internal clock that rallies the body to tackle the day's demands in the morning and slows it down at night, allowing the body to rest and repair. 'Evolution has built this beautiful timekeeping mechanism, but the clock is not absolutely perfect and needs to be nudged every day,' says Dr. David Berson, whose lab at Brown University studies how the eye communicates with the brain. Dr. Patricia Turner, an ophthalmologist who with her husband, Dr. Martin Mainster has written extensively about the effects of the aging eye on health, estimate that by age 45, the photoreceptors of the average adult receive just 50 percent of the light needed to fully stimulate the circadian system, by age 55, it dips to 37 percent, and by age 75, to a mere 17 percent and recommend that people should make an effort to expose themselves to bright sunlight or bright indoor lighting when they cannot get outdoors and have installed skylights and extra fluorescent lights in their own offices to help offset the aging of their own eyes. 'In modern society, most of the time we live in a controlled environment under artificial lights, which are 1,000 to 10,000 times dimmer than sunlight and the wrong part of the spectrum,' says Turner. 'We believe the effect is huge and that it's just beginning to be recognized as a problem.'" -
New Research Shows Cognitive Decline Begins At 45
An anonymous reader writes "New research shows people might start to suffer from cognitive decline as early as age 45. The research, which looked at over 7000 people between the ages of 45 and 70 when the study started, watched participants over a 10 year period. Disturbingly enough, even the youngest participants started declining immediately." -
Study Finds No Link Between Mobile Phones and Cancer (Again)
judgecorp writes "A Danish study of more than 350,000 people found no correlation between using a mobile phone and getting cancer. The results backs up previous work, but researchers say more work is needed to be completely sure." -
Autism-Vax Doc Scandal Was Pharma Business Scam
Sockatume writes "In his second report, Brian Deer exposes how MMR-autism prophet Andrew Wakefield aimed to profit from the vaccine scare. Two years before the research that 'discovered' the MMR-autism link, Wakefield began courting interest in a hundred-million-dollar diagnostics firm. The doctor hoped to seed the company with government legal aid money and profit by charging 'premium prices' for new diagnostic tests to be used in vaccine injury lawsuits. By the time Wakefield published, the proposals had expanded into producing new 'safe' vaccines, two businesses to gather legal aid funding, and interest from partners including Wakefield's own hospital. The scheme ultimately disintegrated with the arrival of new leadership at Wakefield's hospital and ongoing scrutiny into his research." -
Why Doesn't Exercise Lead To Weight Loss?
antdude writes "The New York Times' Well blog reports that 'for some time, researchers have been finding that people who exercise don't necessarily lose weight.' A study published online in September 2009 in The British Journal of Sports Medicine was the latest to report apparently disappointing slimming results. In the study, 58 obese people completed 12 weeks of supervised aerobic training without changing their diets. The group lost an average of a little more than seven pounds, and many lost barely half that. How can that be?" -
Believing In Medical Treatments That Don't Work
Hugh Pickens writes "David H. Newman, M.D. has an interesting article in the NY Times where he discusses common medical treatments that aren't supported by the best available evidence. For example, doctors have administered 'beta-blockers' for decades to heart attack victims, although studies show that the early administration of beta-blockers does not save lives; patients with ear infections are more likely to be harmed by antibiotics than helped — the infections typically recede within days regardless of treatment and the same is true for bronchitis, sinusitis, and sore throats; no cough remedies have ever been proven better than a placebo. Back surgeries to relieve pain are, in the majority of cases, no better than nonsurgical treatment, and knee surgery is no better than sham knee surgery where surgeons 'pretend' to do surgery while the patient is under light anesthesia. Newman says that treatment based on ideology is alluring, 'but the uncomfortable truth is that many expensive, invasive interventions are of little or no benefit and cause potentially uncomfortable, costly, and dangerous side effects and complications.' The Obama administration's plan for reform includes identifying health care measures that work and those that don't, and there are signs of hope for evidence-based medicine: earlier this year hospital administrators were informed by the Centers for Medicare and Medicaid Services that beta-blocker treatment will be retired as a government indicator of quality care, beginning April 1, 2009. 'After years of advocacy that cemented immediate beta-blockers in the treatment protocols of virtually every hospital in the country,' writes Newman, 'the agency has demonstrated that minds can be changed.'" -
Researchers Discover How To Make the Perfect Phone Call
Having made amazing discoveries such as how to make the perfect cheese sandwich, linking heavy caffeine use to sleeplessness, and figuring out where all the teaspoons have gone, science has made the greatest breakthrough yet. They have uncovered the secrets of making the perfect phone call. The perfect phone call clocks in at a mere 9 minutes and 36 seconds, easily 11 minutes shorter than any conversation I've ever had with my mom. Unlike a call to mom, the perfect phone call is almost devoid of any gossip about her divorced neighbor and her heavily tattooed daughter. Instead three minutes should be spent catching up with news about family and friends, one minute on personal problems, a minute on work/school, 42 seconds on current affairs, 24 seconds on the weather, and 24 seconds talking about the opposite sex. What's left of your 9 mins 36 secs is a free for all. -
Internet Sites Biased Towards Supporting Suicide
Believe It Or Not, I Care About You writes "According to a new study in the British Medical Journal which examined the search results for various suicide-related search terms, the most common results supported or encouraged suicide. Wikipedia was one of the most prevalent sources of information, particularly on suicide methods, although the Wikimedia Foundation itself does not encourage suicide. Other studies have shown that media coverage has an effect on suicide particularly with respect to influencing the method chosen. Interestingly, this study notes that suicide rates actually decreased with increased Web usage in England, perhaps because support is readily available to anyone who wants it." -
Fish Poison Makes Hot Feel Cold and Vice Versa
SoyChemist writes "Ciguatoxin causes bizarre neurological symptoms including temperature reversal, a burning sensation, and an imaginary feeling of loose teeth. It is produced by algae and accumulates in the fatty flesh of tropical fish. While traveling to the tropics, a man from England ate some bad seafood that contained the unusual poison. His story, and the tale of some unfortunate sailors of an earlier age who suffered the same affliction, appeared in the current issue of Practical Neurology and was summarized on the Wired Science Blog. Both the Wired blog and the peer-reviewed journal neglected to mention that the potent neurotoxin has been made from scratch by organic chemists." -
Nobel Laureate Attacks Medical Intellectual Property
An anonymous reader writes "Nobel prize-winning economist Joseph Stiglitz, who was fired by the World Bank blasted drug patents in an editorial in the British Medical Journal titled 'Scrooge and intellectual property rights.' 'Knowledge is like a candle, when one candle lights another it does not diminish its light.' In medicine, patents cost lives. The US patent for turmeric didn't stimulate research, and restricted access by the Indian poor who actually discovered it hundreds of years ago. 'These rights were intended to reduce access to generic medicines and they succeeded.' Billions of people, who live on $2-3 a day, could no longer afford the drugs they needed. Drug companies spend more on advertising and marketing than on research. A few scientists beat the human genome project and patented breast cancer genes; so now the cost of testing women for breast cancer is 'enormous.'" -
Medicine And Open Source?
A reader writes: "The British Medical Journal (BMJ) has an editorial on Linux and open source (BMJ 2000;321:976). Also available online." There's been a lot of attention about medical usage of open source software, but not for the typical free reasons, but because when lives are on the line, you want to be able to depend on software not to crash, and open source has a well-deserved reputation for stability.