Scientists Create Mice From 2 Fathers
An anonymous reader writes "Using stem cell technology, reproductive scientists in Texas, led by Dr. Richard R. Behringer at the M.D. Anderson Cancer Center, have produced male and female mice from two fathers. The study was posted Wednesday at the online site of the journal Biology of Reproduction. The achievement of two-father offspring in a species of mammal could be a step toward preserving endangered species, improving livestock breeds, and advancing human assisted reproductive technology. It also opens the provocative possibility of same-sex couples having their own genetic children, the researchers note."
It also opens the provocative possibility of same-sex couples having their own genetic children, the researchers note.
This isn't going to go down well with the God Squad.
as long as they don't force me to have sex with my father
What happens in case they combine two Y chromosomes?
Son of Kronar
(nsfw)
45 5F E1 04 22 CA 29 C4 93 3F 95 05 2B 79 2A B2
welcome our new gaylords. Or gaylings. whatever.
All the world needs is bloody gay mice.
The gay marriage future looks bright.
Now instead of the mice in my house just eating my cheese, I have to worry about them reupholstering my furniture.
Yeah yeah yeah. Just two fathers. That's some trick there, getting a male to generate a fetus. What an age we live in.
Cut me a break, and at least report that a female was in some way required, OK? I know it does not have the same "zing" as a story not involving females at all, but still.
To me, this is one of them. Don't you agree? What about if you could make a human-animal hybrid, would you do that?
It also opens the provocative possibility of same-sex couples having their own genetic children, the researchers note.
As long as they're happy with only female children, or are males themselves.
Ask me about repetitive DNA
What about every American's four fathers?
Farewell to "your momma" jokes
so lesbian couples will only have daughters? and the daughters are probably lesbians too? Amazons!
Couldn't those scientists just have adopted, if they wanted them so badly? Mice prodution is already high enough - now the issue should be distribution. Think of the baby mice!
It also opens the provocative possibility of same-sex couples having their own genetic children, the researchers note.
Refining the process in humans would probably result in the production of numerous fetuses with congenital defects resulting in death soon after birth, similar to what's been seen in cloning of various animals. Intentionally doing such a thing would (or, at least, should) never be permitted by a civilized society, not even in the name of "equality".
Question for great Radio Eriwan: Can two men have baby?
Answer from great Radio Eriwan: In principle, no, but testing continues.
And now they go ahead and just do it. Way to ruin a perfectly good joke.
But on the bright side, I can see the religious fundies already throw a tantrum. So one joke got replaced with another one, I think life balances itself out.
I've always assumed that females are more durable than males (long life span, more resistant to diseases, etc). If there's one sex in danger of extinction, it's the males of the species. So I think it's more valuable research to try and figure out how to create male babies from the eggs or stem cells of two donor mothers. Of course, we can always resort to cloning, but that would not lead to the diversity that's the main benefit of sexual reproduction (aside from pleasures of the one-night stand that is).
As long as we still got billions to pump into a holy war against freedom (or something like that, it's kinda fuzzy), I see no harm in pumping a few thousand bucks into giving gays the ability to procreate.
I'd rather give money to fags than to wankers, given a choice.
And before you ask what war has to do with gay procreation: I'll think of an answer once you tell me what the latter has to do with "people dying around the globe from diseases".
We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
dying... from deceases
I like that.... i want to dye from deceasing... oooh! ooooh! can i tie-dye from deceasing?
Craig: "That would be so cool."
soylentnews.org Go there to enjoy the people!
A cure for sexual reproduction!!
So the question is, did they take all the good genes from the two fathers but somehow accidentally a smaller less perfect twin was produced and.... http://www.imdb.com/title/tt0096320/ (for those that don't get the reference, jokes are always best if they need to be explained) - Christopher
Well, then life's a bitch and then your zygote dies.
The Y chromosome is not a variant of the X chromosome. The X chromosome is one you actually need. The Y chromosome actually has very little information, and most of it related to testosterone production and sperm production. It doesn't even encode most of the differences between a male and a female body. Those are already taken care of by other proteins and testosterone.
In programming terms the Y chromosome is a little more than just a flag, but basically at an oversimplified level you can view it as a flag. The real important information is elsewhere.
So basically it's akin to, dunno, if you took out the .exe from the world of warcraft directory, but flagged it as Cataclysm compatible twice. It ain't gonna be very useful.
A polar bear is a cartesian bear after a coordinate transform.
Depending on the way you decease, you could dye your surroundings blood-red, shit-brown, or any other bodily colour.
IN YOUR FACE LESBIANS :D
You think that's bad? How about, now when the boss rides your ass all afternoon, you can actually get pregnant? Man, trust science to make IT and programming jobs even shittier ;)
A polar bear is a cartesian bear after a coordinate transform.
I'd rather give money to fags than to wankers, given a choice.
You'll disappoint a lot of slashdotters here.
Said by the XENOPHOBIC annonymous writer.
Despite the stereotype, males do produce the seed which is life. Females just produce eggs. So this shouldn't be surprising.
So the same method can theoretically be applied to two sperms from the same male. I can be the father and mother of my own child then.
Should he/she be considered my "child" or my "clone"?
Search RapidShare and MegaUpload!
Children of two fathers? Now we can fix everythin! a Raymon - Stallman children would settle the differences between vi and emacs!
A while back, scientists cured obesity in mice. Now, in addition to a mouse having a mom & dad, it can also have a dad & dad and a mom & mom. Mice have it all. Humans are still waiting. John Steinbeck would be pleased.
HRH The Duke of Windsor
Gay offspring provocative? Why?
As I see it, while most people prefer a partner of the opposite sex, some prefer a same sex partner.
The only downside to such an arrangement that I can think of is that such a couple cannot have offspring.
Now, with this technique, they might! So this should be anti-provocative, if anything, removing (or at least reducing) the only real "problem" of same sex partners.
Did anyone else read this as "Scientists Create Mice from 2 Feathers" the first time? That woulda been wayyyyyyyyyyyyyyyyyyy cooler!
In other news, NBC sues for patent infringement, claiming hit TV 80's show, "My Two Dads" was their idea.
has two daddies now.
I'm not sure that is a good idea.
Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
I'm reading Oxygen by Nick Lane, and recreating with male mitochondria is a universal no no. Even worms while forming excrete the male mitochondria from the gametes used to form it.
The male mitochondria passed on is aged and defective, the female mitochondria an unused preserved version.
In other words, there's a reason it doesn't work the way it's being forced to work. That's why we have sexes. Thank God or evolution, your choice.
rd
I'm chronically heterosexual, but I have to say that if there is a genetic imperfection that needs to be fixed, it is the genetic imperfection that produces offspring that equate homosexually with pedophilia and bestiality. The goat and the child cannot consent, but an adult male can, and if psychology is right those on that side of the debate are also often deathly afraid that they might. Furthermore, smoking crystal meth is a choice, at least the first time you do it, yet most people are perfectly OK with judging that behavior and saying it it morally wrong, even though they preach freedom of choice. Either the whole human race is moronic on every issue (and I admit an argument to that effect could be made), or these things are not as clear cut as you assert them to be.
Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
Wouldn't it be akin to having biological children with your own identical twin, with a high likelihood of birth defects, since your two sets of chromosomes are being remixed, possibly making your child getting two "bad" copies of some gene? It won't be like a clone at all.
That would have to really confuse a kid.
My karma is not a Chameleon.
oh come on, it was a joke! these people have no sense of humor...
weinersmith
I wouldn't want to sit at that christmas table...
Jesus mice, the mice with TWO fathers.
He who knows best knows how little he knows. - Thomas Jefferson
Isnt there Mother?
damn faggots
That's good news for Lonesome George and his species(assuming you could get male and female offspring from a single father). Sure, there would be heavy inbreeding but it would not be worse than most European royal families.
Thanks--I'll be here all week.
could have daughters or sons
XY+XY -> XY/XX
but a gay female couple can only have daughters
XX+XX -> XX
intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
Complete Androgen Insensivity Syndrome.
Biologically female except for the gonads. They have XY chromsomes but develop as women because
they lack the receptors for male hormones. Also because they lack the male hormone receptors
they typically have very feminine features even for women.
When I first read this I thought, "Okay they got 2 mice from 2 fathers. Lots of people have children from two fathers." Poorly worded.
As for all the religious talk, if I had enough mod points I'd Off Topic all of them.
Medicine is to human what mechanic is to machines. The difference is.. for all machines out there, there are instruction manuals.. Ours.. is being figured out, little by little, everyday. Of course, I can only imagine what the Pope will say about the first human produced from 2 people with the same gender.. :) On the other hand.. who wants Rosie O'Donnell to be able to have babies?? :P
Wrong.
The Y chromosome is totally unlike the X.
The Y chromosome is even coded differently, with redundant duplications.
They even look very differently
http://www.ingender.com/cs/blogs/gender_selection_news/y-chromosome.jpg
Well I am guessing (please correct and educate me here) that a womb was needed to bring the fertilised cells through embryonic stages to normal birth? So that means two women could have a child together without input from a man? Two men will still need a woman to carry the embryo through til birth though?
More like end game for men, rather than for women here. Might be all that radical 60s feminist rhetoric about men not being needed any more could come true?
which father was breastfeeding...
"Brother from another Mother" will mean something completely different.
Tell you what, when you can create a fetus from the same sex then you have done something, otherwise you still can't get around the fact that you must have male and female to create offspring so to simplify it for you simple minded fools out there, you can try as hard as you can but there is a reason why you can't do it and while humankind always intends to "do good" for mankind there is always at least one idiot that says "I wonder if I can do this" and then we have unintended consequences...
If two sexes are no longer required to sustain genetic diversity, what will the purpose of men be?
Only women have the components required to gestate a fetus to term, which is a major requirement to providing continuity to the species.
Maybe it would be possible to create a gestation chamber or use a different mammal for gestation, but the likelihood of doing this due to the cost is extremely low.
Men will become truly redundant. This development spells the doom of the Male sex. We may be two or three generations away from the matriarchical lesbian society.
-- Game over man, game over!
In related news, God-fearing parents in Middletown, Kansas protested the local school board's approval of the new Disney Interactive educational game "Mickey Has Two Daddys" for grades 1 to 3. Students who have played the game have told everyone not to worry because the camera "sucked balls" and the controls were "totally tardo".
I think these mice would be better off adopting.
If they believed that the person is alive at the moment of conception, they would FIGHT against raped women getting an abortion. After all , the person is a person at the moment of conception, be it a rape or consensual. But in practice this is not what happen, except for really a minority of pro life. Most accept that abortion is done in case of rape. And here is the cinch. From the point of view of the fecundated egg or whatever, there is NO DIFFERENCE whether it was a rape or not. if one give the CHOICE to the women to abort in case of rape, DESPITE having the fecundated egg considered a human at conception, then there is no reason from the fecundated egg side to NOT give the same choice in case the egg was fecundated in any other situation than rape. No, the only reason to make a difference , is to hinge whether the fecundation was consensual or not, ergo, the reason is not depending on the egg being fecundated, the life begin, but rather, the reason being was the sex consensual or not. In other word I would wager this is more a PUNISHMENT for having consensual sex, rather than to save a life started. In other word, the "life start at fecundation" is bullshit. If it was not, then they would loudly and clearly say that raped women should not be aborted. They should just admit that they wish to see the women punished for having sex.
Is anyone else disgusted by the fact that since the beginning of mankind (whatever the source) the natural fact of life is that it takes one man and one woman to procreate? and now a couple scientists want to re-engineer that core principle of life. If you believe God created man, this is wrong. If you believe evolution governs life, this is wrong.
We still have nothing but week inferences about how the super computer in a living cell work or how the instructions on a DNA strand actually produce a full body. And yet here we are trying to negate all gender value.
Cure all the genetic diseases and cancers plaguing the world and THEN we can talk about altering core principles that govern life.
That only applies to those that don't understand the differences between embryonic stem cells and adult stem cells.
I am against embryonic stem cells because I don't feel that we should profit (in knowledgebase) by murder, which is how I view abortion (Genetically, the fetus is human, unique from its mother, and it is alive, thus ending its life intentionally is murder). Not trying to Godwin myself, but the concentration camps of Germany used humans as lab rats and developed theories based on those deadly tests. That knowledge is forever tainted by how it was obtained.
Adult stem cells, on the other hand, are equivalent to skin grafts, they take a part of yourself, leaving most of you, and I have no problem with that, as long as you are consenting.
I think you not only failed to RTFA, but you also failed to read the fscking summary. The whole issue that sparked this thread is that scientist now thing it may well be possible to pass on their genes to a sibling through this new technique.
Also, your post doesn't take into consideration that, if there is in fact such a gene, it hasn't "taken care of itself" throughout the course of human history.
Before you go asserting that this fact is proof that there is no such gene, don't fail to realize that even before the technology that already exists for one of the pair to pass on the genes: Artificial Insemination, there was always the old fashioned practice of pretending you are straight and getting married and having children, and getting your snausages on the down low.
Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
This is awesome.
The Kruger Dunning explains most post on
One of the mice was later reported to have said, "The experience was true bad as he would have preferred to have passed a kidney stone!"
And here I thought eventual acceptance of gay couples might actually lead to a higher rate of adoption. Thanks, Science, for keeping our orphanages full of unwanted kids.
How does it feel to be a liar with pants constantly on fire?
Great, not they have one of the tools they will eventually use to take over our solar system....
Tsukasa: All I really want, is to be left alone...
There could be many other factors distorting natural human behavior in modern society - much more chemical exposure (BPA, pthalates, etc.), an unnatural social order (nuclear families, lack of tribal focus), and vastly increased isolation. It's a wonder that we're functional at all.
the gay male couple can have only one kind of daughter genetically, and two kinds of sons genetically
X1Y1 + X2Y2 -> X1X2/ X1Y2/ X2Y1
but a gay female couple can have 4 kinds of daughters genetically
X1X2 + X3X4 -> X1X3/ X1X4/ X2X3/ X2X4
(excluding straight up clones, only considering recombination)
intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
I hope this is included in some future South Park episode LOL.
Where's the fetus going to gestate? You going to keep it in a box?
So, eventually two dudes can produce offspring, but I'm not allowed to clone myself? WTH
/\/\icro/\/\uncher
I always thought that women would get rid of men first, never thought that men would get rid of women first.
I don't look forward to a future without a home cooked meal. But at least, less DWTS on TV.
I hope they didn't call the mouse Luke.
Mouse1: I am your father
Mouse2: No, I am your father
It is written in Levsquiticus 18:22. Mice shall not lay with mice as he would with a micette! SINN SIIIIINNNNNNNNN
These are Mice of the DEEEVVVVILLLLLLL !! the DEEEEEVVVVIIIILLLLLLLLLL
Squweh will punish you for your sins!
Are you pondering what i'm pondering?
Now we don't need you either!!! :D
This is a rather sensationalist report. I'm not faulting the submitter, I go back to the source. Let's step through it, shall we?
They are taking a male embryo and generating a stem cell line from it. They then have a way of selecting for cells that have lost their Y chromosome, creating an XO cell line.
Now at this point, I would not even consider the cell line to be male. Classically in humans, XO individuals are considered females with Turner's Syndrome. The source may have been a male cell line, but by removing the Y, especially at a stem-cell stage, you have created a female with a genetic disorder no matter if it was an XX->XO or XY->XO
But still, let us give them the benefit of the doubt and consider the cell line to be male.
They then take the XO cells and inject them into a fully female zygote. This creates a chimeric organism, or simply an organism that is comprised of cells from more than one individual. This can happen naturally, most notably in the case of when one parental twin absorbs the other in womb. Most individuals with this condition never realize their dual nature, but there have been some notable exceptions.
In this case, the resultant animal is female, with some "male" cells making up various bits and parts of the body. But overall, the form is female, not male.
Anyway, if the right sort of chimera is formed, within this chimeric XX/XO organism, *some* of the egg cells will be from the XO injected line. The cells that undergo the right meiosis will contain the right "half" of the equation and keep the X.
If that resultant egg is then fertilized normally by sperm, then yes, you have technically created a new organism that has it's DNA source from two males. One normal male, and one male *line* that was manipulated to being what is classically considered female, and hosted in a female body.
What it most certainly is NOT, is the collection of sperm cells from two males and generating offspring from it.
Dude, thats so gay.
Unless "prefers male / female" is just as simple as "prefers guitar / electronic music". Sure there's plenty of potential for nurture - if you grow up surrounded by guitar musicians, for example. On the other hand there are societal pressures, preferring guitar music is (arguably) the societal norm, as is preferring the opposite sex to same or either.
In terms of music I mostly prefer electronic, but there's plenty of guitar I like too, i guess I have an 80/20 split in that regard. And sexually I'm about a 95/5 split, with the 5% being the odd time I really would like some cock
My reckoning is that as society as a whole gets more relaxed, groovy, open and generally "who cares" about sexuality more and more people will feel absolutely no pressure either way and will openly call themselves bisexual. that is assuming that in a century or three those labels even apply any more
If you don't risk failure you don't risk success.
I suppose this must have come about since the catholic church allowed male prostitutes to wear condoms.
America, Home of the Brave.