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The head of the World Health Organization, Dr Tedros Adhanom Ghebreyesus, said air pollution is the "new tobacco" that is killing 7 million people a year and harming billions more. "The world has turned the corner on tobacco. Now it must do the same for the 'new tobacco' -- the toxic air that billions breathe every day," said Tedros. "No one, rich or poor, can escape air pollution. It is a silent public health emergency." The Guardian reports: "Despite this epidemic of needless, preventable deaths and disability, a smog of complacency pervades the planet," Tedros said, in an article for the Guardian. "This is a defining moment and we must scale up action to urgently respond to this challenge." The WHO is hosting its first global conference on air pollution and health in Geneva next week, including a high-level action day at which nations and cities are expected to make new commitments to cut air pollution.

Tedros said: "A clean and healthy environment is the single most important precondition for ensuring good health. By cleaning up the air we breathe, we can prevent or at least reduce some of the greatest health risks." The WHO is working with health professionals not only to help their patients, but also to give them the skills and evidence to advocate for health in policy decisions such as moving away from fossil-fuel-powered energy and transport. "No person, group, city, country or region can solve the problem alone," he said. "We need strong commitments and actions from everyone."

The head of the World Health Organization, Dr Tedros Adhanom Ghebreyesus, said air pollution is the "new tobacco" that is killing 7 million people a year and harming billions more. "The world has turned the corner on tobacco. Now it must do the same for the 'new tobacco' -- the toxic air that billions breathe every day," said Tedros. "No one, rich or poor, can escape air pollution. It is a silent public health emergency." The Guardian reports: "Despite this epidemic of needless, preventable deaths and disability, a smog of complacency pervades the planet," Tedros said, in an article for the Guardian. "This is a defining moment and we must scale up action to urgently respond to this challenge." The WHO is hosting its first global conference on air pollution and health in Geneva next week, including a high-level action day at which nations and cities are expected to make new commitments to cut air pollution.

Tedros said: "A clean and healthy environment is the single most important precondition for ensuring good health. By cleaning up the air we breathe, we can prevent or at least reduce some of the greatest health risks." The WHO is working with health professionals not only to help their patients, but also to give them the skills and evidence to advocate for health in policy decisions such as moving away from fossil-fuel-powered energy and transport. "No person, group, city, country or region can solve the problem alone," he said. "We need strong commitments and actions from everyone."

schwit1 shares a report from Engadget: Sidewalk Labs, an Alphabet division focused on smart cities, is caught in a battle over information privacy. The team has lost its lead expert and consultant, Ann Cavoukian, over a proposed data trust that would approve and manage the collection of information inside Quayside, a conceptual smart neighborhood in Toronto. Cavoukian, the former information and privacy commissioner for Ontario, disagrees with the current plan because it would give the trust power to approve data collection that isn't anonymized or "de-identified" at the source. "I had a really hard time with that," she told Engadget. "I just couldn't... I couldn't live with that."

Cavoukian isn't the first privacy expert to abandon the Quayside project. Saadia Muzaffar, founder of TechGirls Canada, left the Digital Strategy Advisory Panel earlier this month. In a resignation letter, she said Waterfront Toronto had shown "apathy and [an] utter lack of leadership regarding shaky public trust and social license." The advisory panel was attended "in good faith," she said, but showed "a blatant disregard for resident concerns about data." These disagreements will add to the concerns of Torontonians. Sidewalk Labs still has time to address these issues and create a master plan that will be accepted by everyone. If the company continues to lose public trust, though, there's a good chance residents and government officials will make up their minds and reject the plan before reading the first page.

An anonymous reader quotes a report from The Guardian: Evidence that an entire class of pesticides threatens the health of children and pregnant women is now so arresting that the substances should be banned, an expert panel of toxicologists has said. Exposure to organophosphates (OPs) increases the risk of reduced IQs, memory and attention deficits, and autism for prenatal children, according to the paper, published in Plos Medicine. More than 10,000 tonnes of OP pesticides are sprayed in 24 European countries each year and usage is higher in the US, where the Trump administration is appealing against a federal court ban on chlorpyrifos, one of the most popular agricultural insecticides.

Irva Hertz-Picciotto, the paper's lead author and director of the UC Davis environmental health sciences centre, said: "We have compelling evidence from dozens of human studies that exposures of pregnant women to very low levels of organophosphate pesticides put children and fetuses at risk for developmental problems that may last a lifetime. By law, the EPA cannot ignore such clear findings: It's time for a ban not just on chlorpyrifos, but all organophosphate pesticides." Bruce Lanphear, one of the paper's co-authors, said: "We found no evidence of a safe level of organophosphate pesticide exposure for children. Well before birth, organophosphate pesticides are disrupting the brain in its earliest stages, putting them on track for difficulties in learning, memory and attention, effects which may not appear until they reach school-age. Government officials around the world need to listen to science, not chemical lobbyists."

An investigation by Italy's competition authority has found that software updates "significantly reduced performance" on Samsung's Android handsets and iPhones. From a report: Apple and Samsung are being fined Euro 10m ($11.4m) and Euro 5m ($5.7) respectively in Italy for the "planned obsolescence" of their smartphones. An investigation launched in January by the nation's competition authority found that certain smartphone software updates had a negative effect on the performance of the devices. Believed to be the first ruling of its kind against smartphone manufacturers, the investigation followed accusations operating system updates for older phones slowed them down, thereby encouraging the purchase of new phones.

In a statement the antitrust watchdog said "Apple and Samsung implemented dishonest commercial practices" and that operating system updates "caused serious malfunctions and significantly reduced performance, thus accelerating phones' substitution." It added the two firms had not provided clients adequate information about the impact of the new software "or any means of restoring the original functionality of the products."

An anonymous reader quotes a report from The New York Times: In a pilot study with a small sample size, researchers looked for microplastics in stool samples of eight people from Finland, Italy, Japan, the Netherlands, Poland, Russia, the United Kingdom and Austria. To their surprise, every single sample tested positive for the presence of a variety of microplastics (Warning: source may be paywalled; alternative source). In a pilot study with a small sample size, researchers looked for microplastics in stool samples of eight people from Finland, Italy, Japan, the Netherlands, Poland, Russia, the United Kingdom and Austria. To their surprise, every single sample tested positive for the presence of a variety of microplastics.

The new paper, which was presented Monday at a gastroenterology conference in Vienna, could provide support for marine biologists who have long warned of the dangers posed by microplastics in our oceans. But the paper suggests that microplastics are entering our bodies through other means, as well. To conduct the study, they selected volunteers from each country who kept food diaries for a week and provided stool samples. Dr. Philipp Schwabl, a researcher at the Medical University of Vienna who led the study, and his colleagues analyzed the samples with a spectrometer. Up to nine different kinds of plastics were detected, ranging in size from .002 to .02 inches. The most common plastics detected were polypropylene and polyethylene terephthalate -- both major components of plastic bottles and caps.

AmiMoJo quotes the Guardian: Plans to build a British jet-powered car to speed at more than 1,000mph through the desert have hit quicksand, after the company behind the Bloodhound project entered administration. The dream of an ultra-fast car to break the land speed record led to the creation of Bloodhound Programme Ltd in 2007, with the idea of also engaging schools and students in engineering. Bloodhound has already built and tested a viable racing car to speeds of 200mph, but the project is in debt and needs to find £25m or face being wound up... Bloodhound said its programme had been a catalyst for research and development, as well as helping interest schoolchildren worldwide in science and engineering, with an associated educational campaign reaching more than 2 million children...

The planned car is a combination of jet, F1 car and spaceship that would cover the length of four and a half football pitches in a second.

Ian Sample, writing for The Guardian: The growth of internet access around the world has slowed dramatically, according to new data, suggesting the digital revolution will remain a distant dream for billions of the poorest and most isolated people on the planet. The striking trend, described in an unpublished report shared with the Guardian, shows the rate at which the world is getting online has fallen sharply since 2015, with women and the rural poor substantially excluded from education, business and other opportunities the internet can provide.

The slowdown is described in an analysis of UN data that will be published next month by the Web Foundation, an organisation set up by the inventor of the world wide web, Sir Tim Berners-Lee. The data shows that growth in global internet access dropped from 19% in 2007 to less than 6% last year. "We underestimated the slowdown and the growth rate is now really worrying," said Dhanaraj Thakur, research director at the Web Foundation. "The problem with having some people online and others not is that you increase the existing inequalities. If you're not part of it, you tend to lose out."

The south-western Chinese city of Chengdu is planning to launch an illumination satellite in 2020 that is "designed to complement the moon at night," though it would be eight times as bright. "The 'dusk-like glow' of the satellite would be able to light an area with a diameter of 10-80km, while the precise illumination range could be controlled within tens of meters -- enabling it to replace streetlights," reports The Guardian. From the report: The vision was shared by Wu Chunfeng, the chairman of the private space contractor Chengdu Aerospace Science and Technology Microelectronics System Research Institute Co (Casc), at a national mass innovation and entrepreneurship event held in Chengdu last week. Wu reportedly said testing had begun on the satellite years ago and the technology had now evolved enough to allow for launch in 2020. It is not clear whether the plan has the backing of the city of Chengdu or the Chinese government, though Casc is the main contractor for the Chinese space program.

The People's Daily was quick to reassure those concerned about the fake moon's impact on night-time wildlife. It cited Kang Weimin, director of the Institute of Optics, School of Aerospace, Harbin Institute of Technology, who "explained that the light of the satellite is similar to a dusk-like glow, so it should not affect animals' routines."

Huawei's new Mate 20 Pro has a massive screen, three cameras on the back and a fingerprint scanner embedded in the display. From a report: The new top-end phone from the Chinese firm aims to secure its place at the top of the market alongside Samsung, having recently beaten Apple to become the second-largest smartphone manufacturer in August. The Mate 20 Pro follows Huawei's tried and trusted format for its Mate series: a huge 6.39in QHD+ OLED screen, big 4,200mAh battery and powerful new Huawei Kirin 980 processor -- Huawei's first to be produced at 7 nanometres, matching Apple's latest A12 chip in the 2018 iPhones.

New for this year is an infrared 3D facial recognition system, similar to that used by Apple for its Face ID in the iPhone XS, and one of the first fingerprint scanners embedded in the screen that is widely available in the UK, removing the need for a fingerprint scanner on the back or a chin on the front. The Mate 20 Pro is water resistant to IP68 standards and has a sleek new design reminiscent of Samsung's S-series phones, with curved glass on the front and back. The back also has an new pattern etched into the glass, which is smooth to the touch but ridged when running your nail over it.

On the back is a new version of Huawei's award-winning triple camera system using a 40-megapixel standard camera, an 8-megapixel telephoto camera with a 3x optical zoom and new for this year is a 20-megapixel ultra-wide angle camera, replacing the monochrome sensor used on the P20 Pro. The Mate 20 Pro runs EMUI 9, which is based on Android 9 Pie. The variant with 6GB of RAM and 128GB of storage is available for 899 Euro starting today.

"Dire as it is, the latest IPCC report is actually too optimistic," writes Slashdot reader Dan Drollette. "It ignores the risk of self-reinforcing climate feedbacks pushing the planet into chaos beyond human control. So says a team of climate experts, including the winner of the 1995 Nobel for his work on depletion of the ozone layer." From their article: These cascading feedbacks include the loss of the Arctic's sea ice, which could disappear entirely in summer in the next 15 years. The ice serves as a shield, reflecting heat back into the atmosphere, but is increasingly being melted into water that absorbs heat instead. Losing the ice would tremendously increase the Arctic's warming, which is already at least twice the global average rate. This, in turn, would accelerate the collapse of permafrost, releasing its ancient stores of methane, a super climate pollutant 30 times more potent in causing warming than carbon dioxide.

By largely ignoring such feedbacks, the IPCC report fails to adequately warn leaders about the cluster of six similar climate tipping points that could be crossed between today's temperature and an increase to 1.5 degrees -- let alone nearly another dozen tipping points between 1.5 and 2 degrees. These wildcards could very likely push the climate system beyond human ability to control. As the UN Secretary General reminded world leaders last month, "We face an existential threat. Climate change is moving faster than we are.⦠If we do not change course by 2020, we risk missing the point where we can avoid runaway climate change, with disastrous consequences."
In related news, a court in The Hague "has upheld a historic legal order on the Dutch government to accelerate carbon emissions cuts, a day after the world's climate scientists warned that time was running out to avoid dangerous warming. Appeal court judges ruled that the severity and scope of the climate crisis demanded greenhouse gas reductions of at least 25% by 2020 -- measured against 1990 levels -- higher than the 17% drop planned by Mark Rutte's liberal administration. The ruling -- which was greeted with whoops and cheers in the courtroom -- will put wind in the sails of a raft of similar cases being planned around the world, from Norway to New Zealand and from the UK to Uganda."

Meanwhile, a new article in GQ cites estimates that more than 70 percent of global emissions come from just 100 companies, complaining that "there is no 'free market' incentive to prevent disaster."

"Dire as it is, the latest IPCC report is actually too optimistic," writes Slashdot reader Dan Drollette. "It ignores the risk of self-reinforcing climate feedbacks pushing the planet into chaos beyond human control. So says a team of climate experts, including the winner of the 1995 Nobel for his work on depletion of the ozone layer." From their article: These cascading feedbacks include the loss of the Arctic's sea ice, which could disappear entirely in summer in the next 15 years. The ice serves as a shield, reflecting heat back into the atmosphere, but is increasingly being melted into water that absorbs heat instead. Losing the ice would tremendously increase the Arctic's warming, which is already at least twice the global average rate. This, in turn, would accelerate the collapse of permafrost, releasing its ancient stores of methane, a super climate pollutant 30 times more potent in causing warming than carbon dioxide.

By largely ignoring such feedbacks, the IPCC report fails to adequately warn leaders about the cluster of six similar climate tipping points that could be crossed between today's temperature and an increase to 1.5 degrees -- let alone nearly another dozen tipping points between 1.5 and 2 degrees. These wildcards could very likely push the climate system beyond human ability to control. As the UN Secretary General reminded world leaders last month, "We face an existential threat. Climate change is moving faster than we are.⦠If we do not change course by 2020, we risk missing the point where we can avoid runaway climate change, with disastrous consequences."
In related news, a court in The Hague "has upheld a historic legal order on the Dutch government to accelerate carbon emissions cuts, a day after the world's climate scientists warned that time was running out to avoid dangerous warming. Appeal court judges ruled that the severity and scope of the climate crisis demanded greenhouse gas reductions of at least 25% by 2020 -- measured against 1990 levels -- higher than the 17% drop planned by Mark Rutte's liberal administration. The ruling -- which was greeted with whoops and cheers in the courtroom -- will put wind in the sails of a raft of similar cases being planned around the world, from Norway to New Zealand and from the UK to Uganda."

Meanwhile, a new article in GQ cites estimates that more than 70 percent of global emissions come from just 100 companies, complaining that "there is no 'free market' incentive to prevent disaster."

The head of the Mozilla Foundation, Mitchell Baker, is warning that companies need to diversify their hiring practices to include more people from backgrounds in philosophy and psychology if they want to tackle the problem of misinformation online. He also "warned that hiring employees who mainly come from Stem -- science, technology, engineering and maths -- will produce a new generation of technologists with the same blindspots as those who are currently in charge, a move that will 'come back to bite us,'" reports the Guardian. From the report: "Stem is a necessity, and educating more people in Stem topics clearly critical," Baker told the Guardian. "Every student of today needs some higher level of literacy across the Stem bases. "But one thing that's happened in 2018 is that we've looked at the platforms, and the thinking behind the platforms, and the lack of focus on impact or result. It crystallized for me that if we have Stem education without the humanities, or without ethics, or without understanding human behavior, then we are intentionally building the next generation of technologists who have not even the framework or the education or vocabulary to think about the relationship of Stem to society or humans or life."

"Stem is a necessity, and educating more people in Stem topics clearly critical," Baker told the Guardian. "Every student of today needs some higher level of literacy across the Stem bases. "But one thing that's happened in 2018 is that we've looked at the platforms, and the thinking behind the platforms, and the lack of focus on impact or result. It crystallized for me that if we have Stem education without the humanities, or without ethics, or without understanding human behavior, then we are intentionally building the next generation of technologists who have not even the framework or the education or vocabulary to think about the relationship of Stem to society or humans or life."

The CEOs of two of the world's most prominent tech companies got into an online spat on Friday over who was doing the most to address homelessness. From a report: Salesforce CEO Marc Benioff and Twitter CEO Jack Dorsey were tweeting at each other about a proposed tax on high-earning San Francisco businesses. It would redirect millions of dollars to help thousands of people who live on the streets, including outside the headquarters of both companies. Benioff tweeted that he was in favor of the tax. Dorsey tweeted that he was not -- prompting a displeased response. "Hi Jack. Thanks for the feedback," Benioff quipped. "Which homeless programs in our city are you supporting? Can you tell me what Twitter and Square & you are in for & at what financial levels? How much have you given to heading home our $37M initiative to get every homeless child off the streets?"

Benioff was referring to an initiative he is spearheading for homeless families. In May he announced that he and his wife would match a $1.5m donation from his company's philanthropic arm. In a second tweet, he alleged that Dorsey had failed to contribute to the city's homeless programs, public hospitals and public schools, despite earning billions and receiving a tax break to relocate in a deprived part of town. Dorsey did not respond.

Huge reductions in meat-eating are essential to avoid dangerous climate change, according to the most comprehensive analysis yet of the food system's impact on the environment. From a report: In western countries, beef consumption needs to fall by 90% and be replaced by five times more beans and pulses. The research [PDF] also finds that enormous changes to farming are needed to avoid destroying the planet's ability to feed the 10 billion people expected to be on the planet in a few decades. Food production already causes great damage to the environment, via greenhouse gases from livestock, deforestation and water shortages from farming, and vast ocean dead zones from agricultural pollution. But without action, its impact will get far worse as the world population rises by 2.3 billion people by 2050 and global income triples, enabling more people to eat meat-rich western diets.

A Russian-American space crew have been forced to make an emergency landing in Kazakhstan after their Soyuz rocket suffered a failure shortly after launching from Russia's Baikonur cosmodrome in one of the most serious space incidents in recent years. From a report: The launch began as a routine affair. Missions bound for the International Space Station (ISS) have been conducted every few months for the past 20 years. But 119 seconds into Thursday's flight, mission controllers on the Nasa broadcast began to speak of a failure. Shaky footage from the capsule's cabin seen during the live broadcast appeared to show objects floating mid-launch. The crew told mission control they felt weightless, an indication of a problem during that stage of the flight. Agitated voices flooding the radio link between mission control and the capsule could be heard on the Nasa broadcast. Details and the exact sequence of events remain unclear, but shortly afterwards the crew initiated an abort and ejected their capsule from the rocket. Judging by the time at which the failure took place, it involved separation of the rocket's second stage -- just before the ship would have ignited the third stage for its final kick to exit the atmosphere. A commentator on Nasa's live broadcast later said that rescue teams had reached the capsule's landing site and the two-person crew were in "good condition."

More than one-third of global music listeners are still pirating music, according to a new report by the International Federation of the Phonographic Industry (IFPI). From a report: While the massive rise in legal streaming platforms such as Spotify, Apple Music and Tidal was thought to have stemmed illegal consumption, 38% of listeners continue to acquire music through illegal means. The most popular form of copyright infringement is stream-ripping (32%): using easily available software to record the audio from sites like YouTube at a low-quality bit rate. Downloads through "cyberlocker" file hosting services or P2P software like BitTorrent came second (23%), with acquisition via search engines in third place (17%).

An anonymous reader quotes a report from The Guardian: Gene editing to correct faulty DNA in human embryos has taken a step closer to becoming a reality, with scientists showing it is possible to correct genetic problems in mice before they are born. Researchers used a form of the gene-editing tool Crispr-Cas9 to introduce a mutation into a gene that would otherwise cause lethal liver failure in mice. While the approach has previously been shown to work in mice after birth, the latest study showed it was also possible to make the all-important tweak before they were born. Writing in the journal Nature Medicine, a team of researchers in the US report how they conducted a series of experiments to explore the use of gene editing in mouse fetuses using a modified form of Crispr that can alter single "base pairs" -- the molecules that couple up to form the rungs of the DNA double helix -- but only cuts one strand of DNA when making a change.

After showing it was possible to make a change at a particular spot in the DNA of liver cells in mouse fetuses, the team focused on a condition known as hereditary tyrosinemia type 1. This is a genetic disease that prevents the body from breaking down an amino acid called tyrosine as it should, and can cause death if left untreated. The team took mice with a genetic mutation that produced a similar condition to hereditary tyrosinemia type 1 and bred them, with the mothers kept on a drug called nitisione. The team then injected 26 of the fetuses with a virus carrying the genetic instructions for making the gene-editing tool, and 27 of them with the same virus but without information for the tool. After birth the baby mice no longer received the drug, and the team watched what happened. "In the non-treated mice, they all died by 21 days of life," said Dr William Peranteau, a pediatric and fetal surgeon at the Children's Hospital of Philadelphia who co-led the study. "However, those that had been treated were able to survive until the end of the study at three months, and looked very similar to another group that had not been injected with anything and were kept on the drug. No gene editing was seen in the mothers who had given birth to the mice.

An anonymous reader quotes a report from The Guardian: In a lab just south of San Francisco I am looking at two blown-up images of microscope slides on a computer screen, side by side. The slides are the same cross-sections of mouse knees from a six-month-old and an 18-month-old animal. The older mouse's image has a splattering of little yellow dots, the younger barely any. That staining indicates the presence of so-called senescent cells -- "zombie cells" that are damaged and that, as a defense against cancer, have ceased to divide but are also resistant to dying. They are known to accumulate with age, as the immune system can no longer clear them, and as a result of exposure to cell-damaging agents such as radiation and chemotherapy. And they have been identified as a cause of aging in mice, at least partially responsible for most age-related diseases. Seeing the slides, it makes me worried about my own knees. "Tell us about it," says Pedro Beltran who heads the biology department at Unity Biotechnology, a 90 person-strong company trying to halt, slow or reverse age-associated diseases in humans by killing senescent cells.

Developing therapies to kill senescent cells is a burgeoning part of the wider quest to defeat aging and keep people healthier longer. Unity, which was founded in 2011, has received more than $385m in funding to date including investment from big tech names such as Amazon's Jeff Bezos and PayPal co-founder Peter Thiel. It went public this May and is valued at more than $700m. Its first drug entered early clinical trials in June, aimed at treating osteoarthritis. Other startups with zombie cells in their sights include Seattle-based Oisin Biotechnologies which was founded in 2016 and has raised around $4m; Senolytic Therapeutics whose scientific development is based in Spain and which was established last September (it won't disclose its financing other than to say it has a first round, which will allow it to reach clinical trials); and Cleara Biotech, formed this June backed by $3m in funding and based in the Netherlands. In addition, Scottish company CellAge, also founded in 2016, has raised about $100,000 to date, partly through a crowdfunding campaign. The report goes on to detail Unity's plan to kill senescent cells. Their method is to target the biological pathways senescent cells use to resist the normal death of aging cells. "The company's approach is to find small molecules (so called 'senolytics') that can do this," reports The Guardian. "But because small molecules, by their nature, can get everywhere in the body, the approach is prone to unwanted side-effects." As a result, the company has turned to localized treatment.

Meanwhile, Oisin is trying to kill all a person's zombie cells in one go. "The idea is to load the body with nanoparticles that insert a 'suicide gene' into every cell," reports The Guardian. "It only triggers if a cell has a lot of particular protein (p16) that acts as a marker of zombie cells, albeit imperfectly." It plans to test this method on late-stage cancer patients next year.

Three scientists have won the Nobel prize in chemistry for their work in harnessing evolution to produce new enzymes and antibodies. From a report: British scientist Sir Gregory P Winter and Americans Frances H Arnold and George P Smith will share the 9m Swedish kronor ($1 million) prize, awarded by the Royal Swedish Academy of Sciences. Half of the prize goes to Arnold, from the California Institute of Technology, for her work on directing the evolution of enzymes -- proteins that speed up chemical reactions. In a nutshell, Arnold introduced genetic mutations into enzymes, and then looked to see what effect the mutations had. She then selected the cases where a particular mutation proved useful -- for example, allowing the enzyme to work in a solvent it would otherwise not work in. Her work has made it possible to cut out the use of many toxic catalysts and has led to the development of enzymes for all manner of fields, including the development of biofuels and the production of pharmaceuticals.

The other half of the award goes to Winter and Smith, for their work on "phage display of peptides and antibodies." A phage is a virus that can infect bacteria, "tricking" bacteria to reproduce it. Smith genetically engineered phages so that they would include a certain molecule on their outer capsule which allowed him to that encompasses out particular proteins crop up on the outer. Winter used this technology to develop new drugs that have transformed medicine, offering therapies for diseases ranging from cancer to autoimmune conditions. Arnold is only the fifth woman to be awarded the prize for Chemistry -- the last female scientist to scoop the award was Ada E. Yonath in 2009 who shared the prize for her work on understanding the structure of ribosomes: the protein-manufacturing structures inside cells.

A new encryption bill that's expected to be passed in Australia is facing strong opposition from tech heavyweights. A new group called "Alliance for a Safe and Secure Internet" has been formed by Australian industry, technology, and human rights groups to persuade the country from passing the bill, reports ZDNet. "The membership of the new alliance consists of Australian Communications Consumer Action Network, Access Now, Ai Group, Australian Information Industry Association, Amnesty International Australia, AMTA, Blueprint for Free Speech, members of Communications Alliance sans NBN, DIGI, Digital Rights Watch, Future Wise, Hack for Privacy, Human Rights Law Centre, Internet Australia, IoT Alliance Australia, and Liberty Victoria." The Guardian also notes that Google and Facebook are part of the group. From the report: The Bill is currently before the Parliamentary Joint Committee on Intelligence and Security, with a minuscule three-week window for submissions closing on Friday, October 12 and a hearing set for Friday, October 19. The proposed legislation would allow the nation's police and anti-corruption forces to ask, before forcing, internet companies, telcos, messaging providers, or anyone deemed necessary, to break into whatever content interception agencies want access to.

"This Bill stands to have a huge impact on millions of Australians, so it is crucial that lawmakers reject this proposal in its present form before we sleepwalk into a digital dystopia," said board member of Digital Rights Watch and alliance spokesperson Lizzie O'Shea. "The rushed processes coupled with the lack of transparency can only mean that expert opinions from Australia and abroad are being disregarded, and deep concerns about privacy erosion and lack of judicial review have simply been tossed aside."

An anonymous reader quotes a report from The Guardian: A new study led by UC San Diego's Katharine Ricke published in Nature Climate Change found that not only is the global social cost of carbon dramatically higher than the federal estimate ($37 per ton) -- probably between $177 and $805 per ton, most likely $417 -- but that the cost to America is around $50 per ton. That's the second-highest in the world behind India's $90, and is also higher than the current federal estimate for the global social cost of carbon. That's a remarkable conclusion worth repeating. Ricke's team found that the cost of carbon pollution to just the United States is probably higher than its government's current estimate of costs to the entire world. And the actual global cost is more than 10 times higher than the federal estimate.

[The Guardian's Dana Nuccitelli] asked Ricke to describe her team's approach in this study: To calculate social cost of carbon, you need to answer four questions in sequence:
1. How would the economy change with no climate change (including GHG emissions)?
2. How does the Earth system respond to emissions of carbon dioxide?
3. How does the economy respond to changes in the Earth system?
4. How should we value losses today vs. in (for example) 100 years?

The team answered these questions using four "modules": a socio-economic module to answer the first question, a climate module to address the second, a damages module to investigate the third, and a discounting module to tackle the fourth.

That study detailed the relationship between a country's average temperature and its per capita GDP, finding a sweet spot around 13C (55F). That's the optimal temperature for human economic productivity. Economies in countries with lower average temperatures like Canada and Russia would benefit from additional warming, but it would slow economic growth for nations closer to the equator with hotter temperatures. The United States is currently right near the peak temperature, whereas many European countries like Germany, the UK, and France are 3-5C cooler, and a bit below the ideal economic temperature. So, continued global warming is worse for the US economy than Europe's.

A trio of laser scientists have won the 2018 Nobel Prize in Physics for their work using intense beams to capture superfast processes and to manipulate tiny objects. From a report: The laureates include Donna Strickland, who is the first woman to win the award in 55 years. Strickland, at the University of Waterloo, Canada, will share half the 9 million Swedish krona (US$1 million) prize with her former supervisor, Gerard Mourou, from the Ecole Polytechnique, in Palaiseau, France. The other half of the prize went to Arthur Ashkin, of Bell Laboratories in Holmdel, New Jersey.

Strickland and Mourou pioneered a way to produce the shortest, most intense pulses of light ever created, which are now used throughout science to unravel processes that previously appeared instantaneous, such as the motion of electrons within atoms, as well as in laser-eye surgery. Ashkin won the prize for his pioneering development of 'optical tweezers', beams of laser light that can grab and control microscopic objects such as viruses and cells. Further reading: The Guardian.

An American and a Japanese scientist have won the 2018 Nobel prize in physiology or medicine for discovery of a revolutionary approach to cancer treatment. The Institute -- 50 professors at the Stockholm facility -- chose the winners of the prize honoring research into the microscopic mechanisms of life and ways to fend off invaders that cut it short. From a report: James Allison and Tasuku Honjo will share the 9m Swedish kronor (roughly $1 million) prize, announced by the Nobel Assembly at the Karolinska Institute in Stockholm. The two scientists have been awarded the prize for their discovery that the body's immune system can be harnessed to attack cancer cells.

The immune system normally seeks out and destroys mutated cells, but cancer cells find sophisticated ways to hide from immune attacks, allowing them to thrive and grow. Many types of cancer do this by ramping up a braking mechanism that keeps immune cells in check. The discovery is transforming cancer treatments and has led to a new class of drugs that work by switching off the braking mechanism, prompting the immune cells to attack cancer cells. The drugs have significant side effects, but have been shown to be effective -- including, in some cases, against late-stage cancers that were previously untreatable. The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday. No literature prize is being given this year.

An anonymous reader shares a report: The world's first autonomous tram was launched in unspectacular style in the city of Potsdam, west of Berlin, on Friday. The Guardian was the first English-language newspaper to be offered a ride on the vehicle developed by a team of 50 computer scientists, engineers, mathematicians, and physicists at the German engineering company Siemens. Fitted with multiple radar, lidar (light from a laser), and camera sensors, forming digital eyes that film the tram and its surroundings during every journey, the tram reacts to trackside signals and can respond to hazards faster than a human. Its makers say it is some way from being commercially viable but they do expect it to contribute to the wider field of driverless technology, and have called it an important milestone on the way to autonomous driving. Travelling in real traffic from the tram depot of Potsdam's transport company ViP, the articulated Combino model tram whirred its way through a high-rise housing settlement in the south-eastern district of Stern on Friday, contending with bikes, prams and cars which sometimes haphazardly crossed its path during the 3.7-mile (6km) route.

An anonymous reader quotes a report from The Guardian: Alcohol is responsible for more than 5% of all deaths worldwide, or around 3 million a year, new figures have revealed. The data, part of a report from the World Health Organization, shows that about 2.3 million of those deaths in 2016 were of men, and that almost 29% of all alcohol-caused deaths were down to injuries -- including traffic accidents and suicide. The report, which comes out every four years, reveals the continued impact of alcohol on public health around the world, and highlights that the young bear the brunt: 13.5% of deaths among people in their 20s are linked to booze, with alcohol responsible for 7.2% of premature deaths overall. It also stresses that harm from drinking is greater among poorer consumers than wealthier ones. While the proportion of deaths worldwide that have been linked to alcohol has fallen to 5.3% since 2012, when the figure was at 5.9%, experts say the findings make for sobering reading.

An anonymous reader quotes a report from The Guardian: Microplastic can escape from polluted waters via flying insects, new research has revealed, contaminating new environments and threatening birds and other creatures that eat the insects. Scientists fed microplastics to mosquito larvae, which live in water, but found that the particles remained inside the animals as they transformed into flying adults. Other recent research found that half of the mayfly and caddisfly larvae in rivers in Wales contained microplastics. The new study, published in the journal Biology Letters, used Culex pipiens mosquitoes, as they are found across the world in many habitats. The researchers found the larvae readily consumed fluorescent microplastic particles that were 0.0002cm in size. The larvae matured into a non-feeding pupa stage and then emerged as adult mosquitoes, which still had significant microplastic within them. The researchers are now studying if this damages the mosquitoes. Professor Amanda Callaghan, at the University of Reading, UK, says it is "highly likely" that other flying insects that begin as water larvae will also eat and retain microplastics. Furthermore, animals that feed on insects, like birds, bats, and spiders, are likely also consuming microplastics.

Bitcoin and other cryptocurrencies are "wild west" assets that expose investors to a litany of risks and are in urgent need of regulation, MPs on the Treasury select committee have said. From a report: The committee said in a report that consumers were left unprotected from an unregulated industry that aided money laundering, while the government and regulators "bumble along" and fail to take action. The Conservative MP Nicky Morgan, the chair of the committee, said the current situation was unsustainable. "Bitcoin and other crypto-assets exist in the wild west industry of crypto-assets. This unregulated industry leaves investors facing numerous risks," Morgan said. "Given the high price volatility, the hacking vulnerability of exchanges and the potential role in money laundering, the Treasury committee strongly believes that regulation should be introduced."

An anonymous reader shares a report: All around us, algorithms provide a kind of convenient source of authority: an easy way to delegate responsibility, a short cut we take without thinking. Who is really going to click through to the second page of Google results every time and think critically about the information that has been served up? Or go to every airline to check if a comparison site is listing the cheapest deals? Or get out a ruler and a road map to confirm that their GPS is offering the shortest route? But already in our hospitals, our schools, our shops, our courtrooms and our police stations, artificial intelligence is silently working behind the scenes, feeding on our data and making decisions on our behalf. Sure, this technology has the capacity for enormous social good -- it can help us diagnose breast cancer, catch serial killers, avoid plane crashes and, as the health secretary, Matt Hancock, has proposed, potentially save lives using NHS data and genomics. Unless we know when to trust our own instincts over the output of a piece of software, however, it also brings the potential for disruption, injustice and unfairness.

If we permit flawed machines to make life-changing decisions on our behalf -- by allowing them to pinpoint a murder suspect, to diagnose a condition or take over the wheel of a car -- we have to think carefully about what happens when things go wrong.

An anonymous reader shares an excerpt from a report via The Guardian: People don't shout in Pontevedra -- or they shout less. With all but the most essential traffic banished, there are no revving engines or honking horns, no metallic snarl of motorbikes or the roar of people trying make themselves heard above the din -- none of the usual soundtrack of a Spanish city. What you hear in the street instead are the tweeting of birds in the camellias, the tinkle of coffee spoons and the sound of human voices. Teachers herd crocodiles of small children across town without the constant fear that one of them will stray into traffic.

"Listen," says the mayor, opening the windows of his office. From the street below rises the sound of human voices. "Before I became mayor 14,000 cars passed along this street every day. More cars passed through the city in a day than there are people living here." Miguel Anxo Fernandez Lores has been mayor of the Galician city since 1999. His philosophy is simple: owning a car doesn't give you the right to occupy the public space. "How can it be that the elderly or children aren't able to use the street because of cars?" asks Cesar Mosquera, the city's head of infrastructures. "How can it be that private property -- the car -- occupies the public space?" Lores became mayor after 12 years in opposition, and within a month had pedestrianized all 300,000 sq m of the medieval centre, paving the streets with granite flagstones. "The historical center was dead," Lores says. "There were a lot of drugs, it was full of cars -- it was a marginal zone. It was a city in decline, polluted, and there were a lot of traffic accidents. It was stagnant. Most people who had a chance to leave did so. At first we thought of improving traffic conditions but couldn't come up with a workable plan. Instead we decided to take back the public space for the residents and to do this we decided to get rid of cars."

Some of the benefits mentioned in the report include less traffic accidents and traffic-related deaths, and decreased CO2 emissions (70%). "Also, withholding planning permission for big shopping centers has meant that small businesses -- which elsewhere have been unable to withstand Spain's prolonged economic crisis -- have managed to stay afloat," reports The Guardian.

"Ireland's government has fully recovered more than [$16 billion] in disputed taxes and interest from Apple, which it will hold in an escrow fund pending its appeal against a European Union tax ruling," reports The Guardian. From the report: The European commission ruled in August 2016 that Apple had received unfair tax incentives from the Irish government. Both Apple and Dublin are appealing against the original ruling, saying the iPhone maker's tax treatment was in line with Irish and EU law. Ireland's finance ministry, which began collecting the back taxes in a series of payments in May, estimated last year the total amount could have reached -- [$17.5 billion] including EU interest. In the end the amount was [$15.2 billion] in back taxes plus [$1.4 billion] interest.

For its part, the commission said it would scrap its lawsuit against Ireland, which it initiated last year because of delays in recovering the money. "In light of the full payment by Apple of the illegal state aid it had received from Ireland, commissioner (Margrethe) Vestager will be proposing to the college of commissioners the withdrawal of this court action," the commission spokesman Ricardo Cardoso said. Ireland's finance ministry said its appeal had been granted priority status and is progressing through the various stages of private written proceedings before the general court of the European Union (GCEU), Europe's second highest court. The matter will likely take several years to be settled by the European courts, it added.

Recycled plastic is already used to make some products, such as guttering and sewage pipes. Now attention is turning to roads. From a report: On September 11th in Zwolle, a town in the Netherlands, a 30-metre bicycle track made from 70% recycled plastic and the rest from polypropylene was opened [Warning: the link may be paywalled; alternative source]. It will be used to test a product called PlasticRoad, which is being developed by two Dutch firms -- KWS, a road builder, and Wavin, a firm that makes plastic piping -- in partnership with Total, a French oil-and-gas firm. PlasticRoad is prefabricated in a factory as modular sections. The sections are then transported to the site and laid end to end on a suitable foundation, such as sand. Because these sections are hollow, internal channels can be incorporated into them for drainage, along with conduits for services such as gas and electricity. For the Zwolle project, sections that were 2.4 metres long and 3 metres wide were used. These were fitted with sensors to measure things such as temperature, flexing and the flow of water through the drainage channels. A second pilot cycleway is being built in the nearby town of Giethoorn.

If all goes well, the inventors hope to develop the idea and make the sections entirely from recycled plastic. Paths, car parks and railway platforms could follow. Eventually, sections for use as actual roads are planned. These could contain sensors for traffic monitoring. In time, the circuits in the plastic roads might extend to assisting autonomous vehicles and recharging electric cars wirelessly. Prefabricated plastic roads should last two-to-three times longer than conventional roads and cost less, the companies claim, mainly because construction times would be reduced by almost two-thirds. Anti-slip surfaces could be incorporated, too, including crushed stones which are traditionally used to dress road surfaces. The sections, when replaced, can also be recycled. But engineers will be watching to see how the track stands up to wear and tear and if the hollow structure causes resonance, which would make such a road unduly noisy.

A number of Slashdot users have shared a leaked Google video from Breitbart, revealing the candid reactions of company executives to Donald Trump's unexpected victory in 2016. The Guardian summarizes: In an hour-long conversation, Google co-founders Sergey Brin and Larry Page, chief executive Sundar Pichai, and executives Kent Walker, Ruth Porat and Eileen Noughton offered their reflections on the election, sought to reassure employees about issues such as immigration status and benefits for same-sex partners, and answered questions on topics ranging from filter bubbles and political polarization to encryption and net neutrality. The executives' reactions ranged from the emotional to the philosophical to the purely pragmatic. Porat appeared near tears in discussing her open support for Hillary Clinton and her father, who was a refugee. Walker discussed global political trends toward nationalism, populism and xenophobia. Pichai noted that the company was already "thoughtfully engaging" with Trump's transition team. While Breitbart argues the video shows evidence of Google's inherent bias against Republicans, Google says the executives are simply sharing their "personal views" and that it has no political bias. It does beg the question, should politics be discussed in the workplace? Longtime Slashdot reader emil writes in response to the video: [...] Disregarding the completely inappropriate expression of partisan views in the workplace, the video claims that "history is our side." These executives appear to have forgotten the incredible tumult in the distant past of the U.S. The last election was not an electoral tie that was thrown into the house of representatives (as was the election of 1800). The last election did not open a civil war as happened in 1861 when Lincoln took office. The last election did not open war with Great Britain, and will likely not precipitate a new set of proposed constitutional amendments to curb presidential power as did either of James Madison's terms in office (War of 1812, Hartford Convention). There may be a time for tears, and a time for hugs, but that time cannot be in the workplace. Most Fortune 500 employees took the news of the latest president elect with quiet perseverance in their professional settings regardless of their leanings, and it is time for Google to encourage the same. "At a regularly scheduled all-hands meeting, some Google employees and executives expressed their own personal views in the aftermath of a long and divisive election season," Google said in a statement. "For over 20 years, everyone at Google has been able to freely express their opinions at these meetings. Nothing was said at that meeting, or any other meeting, to suggest that any political bias ever influences the way we build or operate our products. To the contrary, our products are built for everyone, and we design them with extraordinary care to be a trustworthy source of information for everyone, without regard to political viewpoint."

GCHQ's methods in carrying out bulk interception of online communications violated privacy and failed to provide sufficient surveillance safeguards, the European court of human rights (ECHR) has ruled in a test case judgment. From a report: But the Strasbourg court found that GCHQ's regime for sharing sensitive digital intelligence with foreign governments was not illegal. It is the first major challenge to the legality of UK intelligence agencies intercepting private communications in bulk, following Edward Snowden's whistleblowing revelations. The long-awaited ruling is one of the most comprehensive assessments by the ECHR of the legality of the interception operations operated by UK intelligence agencies. The case was brought by a coalition of 14 human rights groups, privacy organisations and journalists, including Amnesty International, Liberty, Privacy International and Big Brother Watch. In a statement, published on Amnesty's website, Lucy Claridge, Amnesty International's Strategic Litigation Director, said, today's ruling "represents a significant step forward in the protection of privacy and freedom of expression worldwide. It sends a strong message to the UK Government that its use of extensive surveillance powers is abusive and runs against the very principles that it claims to be defending." He added: This is particularly important because of the threat that Government surveillance poses to those who work in human rights and investigative journalism, people who often risk their own lives to speak out. Three years ago, this same case forced the UK Government to admit GCHQ had been spying on Amnesty -- a clear sign that our work and the people we work alongside had been put at risk. The judges considered three aspects of digital surveillance: bulk interception of communications, intelligence sharing and obtaining of communications data from communications service providers. By a majority of five to two votes, the Strasbourg judges found that GCHQ's bulk interception regime violated article 8 of the European convention on human rights, which guarantees privacy, because there were said to be insufficient safeguards, and rules governing the selection of "related communications data" were deemed to be inadequate, The Guardian newspaper reported.

Commenting on the ruling, Snowden, wrote, "For five long years, governments have denied that global mass surveillance violates of your rights. And for five long years, we have chased them through the doors of every court. Today, we won. Don't thank me: thank all of those who never stopped fighting."

Many YouTubers are finding themselves stressed, lonely and exhausted. The Guardian: For years, YouTubers have believed that they are loved most by their audience when they project a chirpy, grateful image. But what happens when the mask slips? This year there has been a wave of videos by prominent YouTubers talking about their burnout, chronic fatigue and depression. "This is all I ever wanted," said Elle Mills, a 20-year-old Filipino-Canadian YouTuber in a (monetised) video entitled Burnt Out At 19, posted in May. "And why the fuck am I so unfucking unhappy? It doesn't make any sense. You know what I mean? Because, like, this is literally my fucking dream. And I'm fucking so un-fucking-happy."

[...] The anxieties are tied up with the relentless nature of their work. Tyler Blevins, AKA Ninja, makes an estimated $500,000 every month via live broadcasts of him playing the video game Fortnite on Twitch, a service for livestreaming video games that is owned by Amazon. Most of Blevins' revenue comes from Twitch subscribers or viewers who provide one-off donations (often in the hope that he will thank them by name "on air"). Blevins recently took to Twitter to complain that he didn't feel he could stop streaming. "Wanna know the struggles of streaming over other jobs?" he wrote, perhaps ill-advisedly for someone with such a stratospheric income. "I left for less than 48 hours and lost 40,000 subscribers on Twitch. I'll be back today... grinding again." There was little sympathy on Twitter for the millionaire. But the pressure he described is felt at every level of success, from the titans of the content landscape all the way down to the people with channels with just a few thousand subscribers, all of whom feel they must be constantly creating, always available and responding to their fans.

"Constant releases build audience loyalty," says Austin Hourigan, who runs ShoddyCast, a YouTube channel with 1.2 million subscribers. "The more loyalty you build, the more likely your viewers are to come back, which gives you the closest thing to a financial safety net in what is otherwise a capricious space." When a YouTuber passes the 1 million subscribers mark, they are presented with a gold plaque to mark the event. Many of these plaques can be seen on shelves and walls in the background of presenters' rooms. In this way, the size of viewership and quantity of uploads become the main markers of value.

Advances in technology mean that a four-day week working week is a realistic goal for most people by the end of this century, the leader of the UK's trade union movement has said. From a report: Frances O'Grady, the general secretary of the Trades Union Congress (TUC), used her speech to the organisation's 150th annual gathering to insist that evolving technology and communications should cut the number hours spent at work. Speaking in Manchester on Monday, O'Grady said: "In the 19th century, unions campaigned for an eight-hour day. In the 20th century, we won the right to a two-day weekend and paid holidays. So, for the 21st century, let's lift our ambition again. I believe that in this century we can win a four-day working week, with decent pay for everyone. It's time to share the wealth from new technology, not allow those at the top to grab it for themselves."

A report by the organisation says postwar economists promised employees would be working a 15-hour week by now and that polls showed a four-day week would be most people's preference. "Instead, new technology is threatening to intensify working lives. For some, the on-demand economy has meant packaging work into ever-smaller pieces of time," the report reads. "This is a return to the days of piece-work, creating a culture where workers are required to be constantly available to work." More than 1.4 million people work seven days a week, with 3.3 million working more than 45 hours a week, according to the report.

Jason Koebler writes: The California Farm Bureau, a group that lobbies on behalf of farmers, reached a "right to repair" agreement with the Equipment Dealers Association (which represents John Deere and other manufacturers) last week. But the specifics of the agreement were written by the manufacturers, and falls far short of providing the types of change that would be needed to make repairing tractors easier. In fact, the agreement makes the same concessions that the Equipment Dealers Association announced in February it would voluntarily give to all farmers. The agreement will not allow farmers to buy repair parts, break firmware DRM, or otherwise alter software for the purposes of repair.

On Sunday haruchai (Slashdot user #17,472) wrote that a 200-year-old museum in Brazil "is burning to the ground and it's likely the entire collection of some 20 million artifacts will be lost." Now CNET reports: The items in the Museu Nacional in Rio may be gone, but Wikipedia doesn't want them to be forgotten... "Did you take a photo of any of them? Help us preserve the memories of as many as we can and add them to @wikicommons," Wikipedia tweeted Tuesday, with an explanation on how to do so...

"The fire at the National Museum of Brazil has led to the devastating loss of 200 years of memory," Katherine Maher, executive director of the Wikimedia Foundation, said in a statement. "At Wikipedia, our community is hard at work every day curating a living record of our shared heritage," Maher said. "With this effort, we're asking people everywhere to join our global community and help the world recover from this collective tragedy."
Wikipedia's tweet included an image urging people to "Add your photo to the sum of all knowledge..."

Multiple Slashdot readers have submitted a blog post by a group of Berlin-based "anti-gentrification activists": Today we occupied the Umspannwerk in Kreuzberg to prevent the planned Google Campus there, to fight against the skyrocketing rents and to open up the space for something better. The Google Campus is intended to be a magnet for annoying young entrepreneurs whose IT-sweatshops ("start-ups") promise to deliver new ideas to Google's company business. New tech companies are driving the rents up in the area higher and higher. The endpoint of this process can be seen in San Francisco, which once must have been a halfway livable city.

While it is especially aggravating that Google, despite its aggressive collection of data, is morphing into Big Brother with a user-friendly face, this is not the decisive factor for us. We would also put a spoke in the wheel of any other company. What happens now in the Umspannwerk instead depends on everyone who fills the house with life. It could become a base for the many initiatives that are currently struggling against rising rents and displacement -- a campus of subversion. But it can also be used as a covered grill area for the cold months, or something more. We call on all rebellious tenants, subversive and precarious cultural workers, work-shy benefit scroungers, strike-hungry air traffic controllers, long-living pensioners, unruly refugees, and all other local pests from the neighborhood (and beyond) to join us in the occupation as quickly as possible. A neighborhood assembly will take place at 6 p.m. to discuss the occupation and how to proceed. Local media has covered the development. [Editor's note: the stories are not in English.] Some context on the local tussle: 'Google go home': the Berlin neighbourhood fighting off a tech giant [May 2018, The Guardian].

An anonymous reader quotes a report from The Guardian: The gut microbiome is the sum total of all the micro-organisms living in a person's gut, and has been shown to play a huge role in human health. New research has found probiotics -- usually taken as supplements or in foods such as yoghurt, kimchi or kefir -- can hinder a patient's gut microbiome from returning to normal after a course of antibiotics, and that different people respond to probiotics in dramatically different ways. In the first of two papers published in the journal Cell, researchers performed endoscopies and colonoscopies to sample and study the gut microbiomes of people who took antibiotics before and after probiotic consumption. Another group were given samples of their own gut microbiomes collected before consuming antibiotics. The researchers found the microbiomes of those who had taken the probiotics had suffered a "very severe disturbance." "Once the probiotics had colonized the gut, they completely inhibited the return of the indigenous microbiome which was disrupted during antibiotic treatment," said Eran Elinav, an immunologist at the Weizmann Institute of Science in Israel and lead author on the studies.

The scientists also compared the gut microbiomes of the gut intestinal tract of 25 volunteers with that of their stools. They found that stool bacteria only partially correlated with the microbiomes functioning inside their bodies. "So the fact that we all almost exclusively rely on stool in our microbiome research may not be a reliable way of studying gut microbiome health," said Elinav. In the second paper, the researchers examined the colonization and impact of probiotics on 15 people by sampling within their gastrointestinal tract. They divided the individuals into two groups: one were given a preparation made of 11 strains of very commonly used probiotics and the other were given a placebo. Of those who were given probiotics, he said, "We could group the individuals into two distinct groups: one which resisted the colonisation of the probiotics, and one in which the probiotics colonized the gut and modified the composition of the gut microbiome and the genes of the host individual."

Zorro (Slashdot reader #15,797) summarizes a new article in the Guardian: The death of a woman hit by a self-driving car highlights an unfolding technological crisis, as code piled on code creates "a universe no one fully understands."

"In some ways we've lost agency. When programs pass into code and code passes into algorithms and then algorithms start to create new algorithms, it gets farther and farther from human agency. Software is released into a code universe which no one can fully understand."
The author dubs these man-made monsters "franken-algos," since "After a time in the wild, we no longer know what they are: they have the potential to become erratic." Self-learning algorithms are already part of the "new all-machine phase" of Wall Street trading, leading to what science historian George Dyson believes are rules "where nobody knows what the rules are: the algorithms create their own rules -- you let them evolve the same way nature evolves organisms."

Where does it end? There's already a robotic sharpshooter policing the demilitarized zone between North and South Korea, and "swarms of coordinated, weaponized drones" already being developed by three different countries. The article suggests re-thinking our legal system to assign blame for any badly malfunctioning algorithms, noting that the Association for Computing Machinery recently updated its code of ethics "along the lines of medicine's Hippocratic oath, to instruct computing professionals to do no harm and consider the wider impacts of their work.... Solutions exist or can be found for most of the problems described here, but not without incentivizing big tech to place the health of society on a par with their bottom lines.

"More serious in the long term is growing conjecture that current programming methods are no longer fit for purpose given the size, complexity and interdependency of the algorithmic systems we increasingly rely on." Toby Walsh, a professor of artificial intelligence at the University of New South Wales, even says "We will eventually give up writing algorithms altogether... "because the machines will be able to do it far better than we ever could. Software engineering is in that sense perhaps a dying profession."

Zorro (Slashdot reader #15,797) summarizes a new article in the Guardian: The death of a woman hit by a self-driving car highlights an unfolding technological crisis, as code piled on code creates "a universe no one fully understands."

"In some ways we've lost agency. When programs pass into code and code passes into algorithms and then algorithms start to create new algorithms, it gets farther and farther from human agency. Software is released into a code universe which no one can fully understand."
The author dubs these man-made monsters "franken-algos," since "After a time in the wild, we no longer know what they are: they have the potential to become erratic." Self-learning algorithms are already part of the "new all-machine phase" of Wall Street trading, leading to what science historian George Dyson believes are rules "where nobody knows what the rules are: the algorithms create their own rules -- you let them evolve the same way nature evolves organisms."

Where does it end? There's already a robotic sharpshooter policing the demilitarized zone between North and South Korea, and "swarms of coordinated, weaponized drones" already being developed by three different countries. The article suggests re-thinking our legal system to assign blame for any badly malfunctioning algorithms, noting that the Association for Computing Machinery recently updated its code of ethics "along the lines of medicine's Hippocratic oath, to instruct computing professionals to do no harm and consider the wider impacts of their work.... Solutions exist or can be found for most of the problems described here, but not without incentivizing big tech to place the health of society on a par with their bottom lines.

"More serious in the long term is growing conjecture that current programming methods are no longer fit for purpose given the size, complexity and interdependency of the algorithmic systems we increasingly rely on." Toby Walsh, a professor of artificial intelligence at the University of New South Wales, even says "We will eventually give up writing algorithms altogether... "because the machines will be able to do it far better than we ever could. Software engineering is in that sense perhaps a dying profession."

New submitter Zarhan writes: Earlier this summer, European Commission conducted a poll on whether EU citizens would like to abolish adjusting their clocks twice a year. The results are now in: 80% of the respondents want to get rid of the changes every spring and autumn. EU Commission is planning to follow through and abolish the practice. In EU, individual countries decide what timezone they belong in, but the clock adjustment is an EU-level decision. The recommendation for now is to stick to summer time year-round, although individual countries will make those decisions. More from DW. The changes are known to affect sleep patterns and causes loss in productivity and even heart attacks, especially when you lose one hour of sleep during the spring change. "I will recommend to the commission that, if you ask the citizens, then you have to do what the citizens say," said Jean-Claude Juncker, the commission's president. "We will decide on this today, and then it will be the turn of the member states and the European parliament."

Air pollution causes a "huge" reduction in intelligence, according to new research, indicating that the damage to society of toxic air is far deeper than the well-known impacts on physical health. From a report: The research was conducted in China but is relevant across the world, with 95% of the global population breathing unsafe air. It found that high pollution levels led to significant drops in test scores in language and arithmetic, with the average impact equivalent to having lost a year of the person's education. "Polluted air can cause everyone to reduce their level of education by one year, which is huge," said Xi Chen at Yale School of Public Health in the US, a member of the research team. "But we know the effect is worse for the elderly, especially those over 64, and for men, and for those with low education. If we calculate [the loss] for those, it may be a few years of education."

The damage in intelligence was worst for those over 64 years old, with serious consequences, said Chen: "We usually make the most critical financial decisions in old age." Rebecca Daniels, from the UK public health charity Medact, said: "This report's findings are extremely worrying." [...] The new work, published in the journal Proceedings of the National Academy of Sciences, analysed language and arithmetic tests conducted as part of the China Family Panel Studies on 20,000 people across the nation between 2010 and 2014. The scientists compared the test results with records of nitrogen dioxide and sulphur dioxide pollution.

Research shows sleep deprivation or excessive hours in bed increase risk of coronary artery disease or stroke. From a report: Six to eight hours of sleep a night is most beneficial for the heart, while more or less than that could increase the risk of coronary artery disease or a stroke, researchers have suggested. The study, presented at the European Society of Cardiology Congress in Munich, indicates sleep deprivation and excessive hours in bed should be avoided for optimum heart health. The study's author, Dr Epameinondas Fountas of the Onassis cardiac surgery centre in Athens, said: "Our findings suggest that too much or too little sleep may be bad for the heart. More research is needed to clarify exactly why, but we do know that sleep influences biological processes like glucose metabolism, blood pressure, and inflammations -- all of which have an impact on cardiovascular disease." Data from more than a million adults from 11 studies was analysed as part of the research. Compared with adults who got six to eight hours of sleep a night, "short sleepers" had an 11% greater risk, while "long sleepers" had 33% increased risk over the next nine years.

"The Big Bang Theory is dead. If you need me, I'll be dancing on its grave," writes a TV columnist for the Guardian: The inexplicably popular geek sitcom has announced that its 12th season will be its last. Its demise should come as a relief to everybody... Producers have promised an "epic creative close" when the series ends in May. After that, The Big Bang Theory will be dead, and nobody will be sad. Except, of course, they will. Because, inexplicably, The Big Bang Theory is still one of the most-watched shows on U.S. television. It regularly gets more than 15 million viewers an episode, and, statistically, not all of them can be incapacitated to the point of being unable to change channels whenever it comes on.

Nothing confuses me more than The Big Bang Theory's success. It has always been markedly less smart than it thought it was; the TV version of someone wearing a "GEEK" T-shirt because they liked a Facebook post about the moon once.... Watch any recent episode of The Big Bang Theory and you'll see that it is barely even a sitcom at this point. It has been going on for so long that the writing, presentation and performances are more or less autonomous. Everyone is just glumly going through the motions, stuck in the tracks they've carved out for themselves over the years. It's like watching a museum exhibit of a sitcom made with mannequins and miserable circus bears.
The actor who plays Sheldon will be 46 when the show ends, the columnist points out, adding that for 12 years he's been playing "a weirdly ageless man-boy trapped in a developmentally arrested closed-loop flatshare scenario more suited to somebody half his age." The Guardian titled their piece "Our Long Nightmare is Finally Over" -- but leave your own thoughts in the comments.

How do you feel about the ending of The Big Bang Theory?

Update from msmash: Two suggested readings, one from The Guardian itself, Critics be damned -- here's why The Big Bang Theory is an unstoppable force with fans, and this four-year-old article from Vulture, Why Are 23.4 Million People Watching The Big Bang Theory?

"The Big Bang Theory is dead. If you need me, I'll be dancing on its grave," writes a TV columnist for the Guardian: The inexplicably popular geek sitcom has announced that its 12th season will be its last. Its demise should come as a relief to everybody... Producers have promised an "epic creative close" when the series ends in May. After that, The Big Bang Theory will be dead, and nobody will be sad. Except, of course, they will. Because, inexplicably, The Big Bang Theory is still one of the most-watched shows on U.S. television. It regularly gets more than 15 million viewers an episode, and, statistically, not all of them can be incapacitated to the point of being unable to change channels whenever it comes on.

Nothing confuses me more than The Big Bang Theory's success. It has always been markedly less smart than it thought it was; the TV version of someone wearing a "GEEK" T-shirt because they liked a Facebook post about the moon once.... Watch any recent episode of The Big Bang Theory and you'll see that it is barely even a sitcom at this point. It has been going on for so long that the writing, presentation and performances are more or less autonomous. Everyone is just glumly going through the motions, stuck in the tracks they've carved out for themselves over the years. It's like watching a museum exhibit of a sitcom made with mannequins and miserable circus bears.
The actor who plays Sheldon will be 46 when the show ends, the columnist points out, adding that for 12 years he's been playing "a weirdly ageless man-boy trapped in a developmentally arrested closed-loop flatshare scenario more suited to somebody half his age." The Guardian titled their piece "Our Long Nightmare is Finally Over" -- but leave your own thoughts in the comments.

How do you feel about the ending of The Big Bang Theory?

Update from msmash: Two suggested readings, one from The Guardian itself, Critics be damned -- here's why The Big Bang Theory is an unstoppable force with fans, and this four-year-old article from Vulture, Why Are 23.4 Million People Watching The Big Bang Theory?

After nearly 60 years of brightening homes and streets, halogen lightbulbs will finally be banned across Europe on 1 September. From a report: The lights will dim gradually for halogen. Remaining stocks may still be sold, and capsules, linear and low voltage incandescents used in oven lights will be exempted. But a continent-wide switchover to light-emitting diodes (LEDs) is underway that will slash emissions and energy bills, according to industry, campaigners and experts. LEDs consume one-fifth of the energy of halogen bulbs and their phase-out will prevent more than 15m tonnes of carbon emissions a year, an amount equal to Portugal's annual electricity usage. Philips, the lighting manufacturer estimates consumer savings of up to 112 pound ($144) a year from the switchover because LEDs last much longer than halogens and use far less power.

An anonymous reader quotes a report from The Guardian: Even the occasional drink is harmful to health, according to the largest and most detailed research carried out on the effects of alcohol, which suggests governments should think of advising people to abstain completely. The uncompromising message comes from the authors of the Global Burden of Diseases study, a rolling project based at the University of Washington, in Seattle, which produces the most comprehensive data on the causes of illness and death in the world. Alcohol, says their report published in the Lancet medical journal, led to 2.8 million deaths in 2016. It was the leading risk factor for premature mortality and disability in the 15 to 49 age group, accounting for 20% of deaths. The study was carried out by researchers at the Institute of Health Metrics and Evaluation (IHME), who investigated levels of alcohol consumption and health effects in 195 countries between 1990 to 2016. They used data from 694 studies to work out how common drinking was and from 592 studies including 28 million people worldwide to work out the health risks. According to the report, "27.1% of cancer deaths in women and 18.9% in men over 50 were linked to their drinking habits." The biggest causes of death linked to alcohol in younger people were tuberculosis (1.4% of deaths), road injuries (1.2%), and self-harm (1.1%).

"Worldwide we need to revisit alcohol control policies and health programs, and to consider recommendations for abstaining from alcohol," said the report's senior author, Professor Emmanuela Gakidou. "These include excise taxes on alcohol, controlling the physical availability of alcohol and the hours of sale, and controlling alcohol advertising. Any of these policy actions would contribute to reductions in population-level consumption, a vital step toward decreasing the health loss associated with alcohol use."

An anonymous reader quotes a report from The Guardian: The latest study provides new evidence that sleep deprivation has a direct influence on basic metabolism and the body's balance between fat and muscle mass. In the study, published in the journal Science Advances, 15 healthy volunteers each attended a testing session on two occasions, once after a normal night's sleep and once after staying up all night. During the visit, they gave samples of fat and muscle tissue and blood. After sleep deprivation, people's fat tissue showed changes in gene activity that are linked to cells increasing their tendency to absorb lipids and also to proliferate.

By contrast, in muscle the scientists saw reduced levels of structural proteins, which are the building blocks the body requires to maintain and build muscle mass. Previous epidemiological studies have also found shift workers and those who sleep less have lower muscle mass. This may be in part down to lifestyle factors, but the latest work shows that there are also fundamental biological mechanisms at play. The study also found an increase in inflammation in the body after sleep deprivation, which is a known risk factor for type 2 diabetes.