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Nanotechnology: Are Molecular Assemblers Possible?

Roland Piquepaille writes "Two experts in the field of nanotechnology, K. Eric Drexler, Ph.D., cofounder of the Foresight Institute in Palo Alto, Calif., and the person who coined the term "nanotechnology," and Richard E. Smalley, Ph.D., a professor at Rice University and winner of the 1996 Nobel Prize in Chemistry, exchanged open letters about "molecular assemblers" -- devices capable of positioning atoms and molecules for precisely defined reactions in almost any environment. These letters are making the -- long -- cover story of the current issue of Chemical & Engineering News. At the end of this rich exchange of four letters, they still disagree about the issue. Drexler thinks "molecular assemblers" are possible while Smalley denies it. Who is right? Don't count on me to give an answer. This summary contains some forceful quotes from the original letters."

513 comments

  1. Raises interesting questions by Steve+'Rim'+Jobs · · Score: 4, Interesting

    If, in the future, copying physical objects is nearly as easy as copying information on a computer, will corporations lobby to pass laws that make it illegal to do so? In other words, will I be arrested one day for making a copy of my friend's Ferrari?

    1. Re:Raises interesting questions by terrox · · Score: 1

      nope
      the assemlber could be copied, everything gets converted into something else more useful to humans
      either it is too expensive to copy things, or too slow, or too unreliable, or everyone quickly copies nukes and blows up the world

    2. Re:Raises interesting questions by Walterk · · Score: 5, Interesting

      Ferraris are not IP, so you could copy it freely. However, this would devaluate all Ferraris and would be frowned upon by the company. Ferrari Inc. would then copyright the design of the car and include a license with your friend's Ferrari.

      By this time it will not be possible to buy a Ferrari, but only to license a copy. Therefore official Ferrari licenses will be a hot commodity for the wealthy and they will slap licenses on the car windows, the cars however will not become their property.

      Of course thieves will see this trend and nab the licenses out of the Ferrari, instead of the car itself, which will be worthless.

      Hence you could copy a Ferrari, but what good would it do you, as it wouldn't be yours anyway.

    3. Re:Raises interesting questions by misterpies · · Score: 1, Insightful


      You can already be arrested for making a copy of your friend's ferrari -- they've got copyright in the design of the car, after all.

      --
      The author of this post asserts his moral rights.
    4. Re:Raises interesting questions by rbullo · · Score: 1

      At the rate we're going, yes. But at the rate we're going, the country will descend into civil war soon after. Or we'll be sheep and I'll be out of here.

      --
      OH NOES!!! IT APPEARS YUO DO NOT HAVE ENOUGH MONEY TO PAY FOR DIS HERE PIZZA! WAHT EVER ARE YOU GOING TO DO!?!?
    5. Re:Raises interesting questions by tsmccaff · · Score: 3, Interesting

      I don't know if current copyright and patent laws can handle these questions. It is legal for me to carve a replica of a wooden chair with a sawblade. Is that substantially different from having a molecular assembler do the job?

      --
      "the starry sky above and the moral law within"-Kant
    6. Re:Raises interesting questions by Pelorat · · Score: 4, Insightful

      What a ridiculous assertion. It is most certainly *not* illegal to build any car from parts, or even to make one car look like another.

      There is an entire 'kit car' industry, you might want to go have a look at it.

    7. Re:Raises interesting questions by Space+cowboy · · Score: 2, Interesting

      Especially if you combine P2P with nanotech. Want something ? Just download the "program" from any.where and create it.

      Wow, we're already shaking the foundations of some markets (low-to-zero-cost products are not historically very common, but digital assets have essentially zero duplication costs), but so far it's been limited to the digital world. Expect major changes if we can at any time expand that into the physical world...

      Simon.

      --
      Physicists get Hadrons!
    8. Re:Raises interesting questions by markfive · · Score: 3, Interesting

      So why not just make a copy of the license?

    9. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      By the time we are able to copy material items, companies would not exist, I think we would be closer to the future portrayed in Star Trek, where money becomes irrelevant.

    10. Re:Raises interesting questions by BorgDrone · · Score: 5, Insightful

      Ferrari Inc. would then copyright the design of the car and include a license with your friend's Ferrari.

      If you're using a molecular assembler to copy the ferrari, you could use it to copy the license certificate, which would be an exact duplicate so unrecognisable from the original.
      Even if they register licensees, you just copy your friends passport (after instructing the assembler to change the photograph) so you can 'prove' you are $FRIEND and you're the legitimate licensee.

      However, if molecular assemblers ever become mainstream I'd rather design my own car and let it assemble that. If everyone is driving a Ferrari I'd rather have something different.

    11. Re:Raises interesting questions by mirko · · Score: 2, Funny

      If everyone is driving a Ferrari I'd rather have something different.

      Well, had you written "Rolls Royce" instead of "Ferrari", I'd have whinned something like : "if it's perfect, I don't care if it's not unique"... ;-)

      --
      Trolling using another account since 2005.
    12. Re:Raises interesting questions by Walterk · · Score: 1

      Ferrari would keep a registry with the licensees, along with DNA of the licensee. So in order for it to be legitimate you would have to have the same DNA as your friend, so in order to have a good copy of the license you'd have to have the same DNA, and be the same person.

      Instead, why just not rob your friend? And why does he have a Ferrari in the first place? What's with your social circle? Does Ashcroft know? ... Hey, this is /.! We don't have social circles around here! You must be a terrorist!

    13. Re:Raises interesting questions by freeze128 · · Score: 3, Funny

      If you're going to copy your friend's Ferrari one atom at a time, you better start now....

    14. Re:Raises interesting questions by jacem · · Score: 3, Interesting

      That is true of course until a Finish auto mechanic name Tinus Lorvads creates a version of the Ferrari from scratch completely free of patented or copywritten source. Of course after this core capability become availably millions of auto mechanics the world over start to make improvements to the Tirrari until through their combined effort a vehicle is developed that can go 1000 MPH gets a million miles to the gallon and is almost impossible to crash.
      Most of the major auto makers of course will than start a propaganda campaign about how bad an dangerous the Tirrari is because the builder has to bolt the seats in himself.

      Why does this sound familiar?

      Jacem

      --
      DOC Disinformation Obfuscation and Confusion
      The carrot to FUD's stick
    15. Re:Raises interesting questions by Anonymous Coward · · Score: 1, Funny

      I make a copy of my friend including the DNA and put my brain in him, and then I drive the ferrari wheeeeeeee!!!!

    16. Re:Raises interesting questions by RLW · · Score: 1

      Did you see Gattaca? if you have a molecular assembler then make a DNA pod for your finger! then when they 'check' your DNA you are your friend!

      With this gadget the physical world becomes much more like the virtual word of software. Owning copies of devices will be cheap and easy. It's the production of new items that will require brain power to think up and testing to 'de-bug'. There will be versions of items just like versions of software. If it works like the matter compiler from 'The Diamond Age' then when you become tired of your toys you can also put them back to be de-compiled and get credit for it's scrap value.

      The broader implication of this will be the impact on jobs. No one will have to work in an assembly line ever again. Combine this kind of construction with advances in robotics then no one will ever be involved in any kind of manual labor. The economy will only have spots for thinkers. So if you can't write a play, design new concepts for new devices/robots or perform some kind of really specialized maintenance that a robot hasn't been designed to for yet, then you're out of luck.

    17. Re:Raises interesting questions by Noren · · Score: 1
      After the first person does this, the companies will have to come up with a new, much improved licensing system:

      Instead of selling you an actual license, you'll get a license to make a license to make a Ferrari. Problem solved!

    18. Re:Raises interesting questions by clambake · · Score: 4, Insightful

      By this time it will not be possible to buy a Ferrari, but only to license a copy.

      Buy with what money? When you can replicate all the food, clothing, shelter, weaponry, medicine, entertainment, and all the general goods you will ever need, what, exactly, is the point of money? Without scarcity, money ceases to exist in ALL it's forms... With a replicator, the entire CONCEPT of economics will go the way of the feudal system; just another quaint idea you can read about in your replicated bookery.

    19. Re:Raises interesting questions by HMA2000 · · Score: 1

      Property Rights are result of scarcity. Modern economic theory (at least the theories most people are familiar with) is built upon the notion of property rights.

      Economics is the study of how humans allocate limited resources to unlimited demands.

      With molecular assemblers scarcity is all but eliminated. This would turn economic theory and property rights on its head. In short, a whole new economic system and associated property rights would have to be developed. Any speculation at this point is just that speculation.

    20. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      To quote Scott Adams "The future will not be like star trek"

    21. Re:Raises interesting questions by erlorad · · Score: 1

      New economy of nanotech age is pretty good described in Diamond Age by Neal Stephenson. Basically, everything that is nano-assembled is close to worthless. Hand-made things and "blueprints" to make something (IP) are considered to be of value.

      There is a huge lower class of people who don't do anything and have access to social welfare nano-feeds that produce basic stuff for free. There's a pretty thin middle class of nerds that create new blueprints and feeds. Upper class is very small and basically they are all Equity Lords, initial owners of the company that patented the technology.

    22. Re:Raises interesting questions by WEFUNK · · Score: 1

      It is legal for me to carve a replica of a wooden chair with a sawblade.

      Are you sure? IANAL, but just because it would be easy and very unlikely that you would be sued, this action wouldn't necessarily be legal if the wooden chair design was patented (with utility or design patent). This might not be usual case today, but I wouldn't be surprised if it became more common in the future -- certainly I've seen a number of simple automotive parts (brackets, etc.) that are covered by design patents, probably to prevent pirating.

      Of course it would still be very easy to do, and maybe a good case for showing the inadequacies of patents. A great example of a very important but very simple physical design that was extensively "pirated" was Eli Whitney's patented cotton gin. The cotton gin is considered a precursor to the the mass production age and delivered unprecedented southern prosperity, but could easily be copied with a simple wooden box and a bunch of nails. This was technically illegal, but the device was such an important innovation and even Eli couldn't keep up with the demand, so after fighting to receive his patent, he either didn't renew it or the government didn't let him depending on which story you read.

      --
      My next sig will be ready soon, but friends can beat the rush!
    23. Re:Raises interesting questions by Breakfast+Pants · · Score: 1

      If you can't write a "play"? Look you are getting way too excited here. Just because you propose that manual labor will disappear does not mean that plays will come back into style, nor that they will make up for a large part of the economy. You seem to think that some invention like this will fix all of our problems, everyone will goto the opera and symphony and have a dandy fop of a good time simply because the world will all be intellectuals (just like you; oh wait, you just think you are some kind of intellectual who is better than the working class because your job deals with ideas and not manual labor. There can be a lot more to a person than just his job you thoughtless fuck).

      --

      --

      WHO ATE MY BREAKFAST PANTS?
    24. Re:Raises interesting questions by Saige · · Score: 2, Interesting

      I would like to believe such a society is not only possible, but likely. However, I don't see a good way to get from here to there. In most western societies, capitalism seems to be a de-facto system, with few people questioning if it's the best way to do things.

      How do we go from a system where everything has a value, and you only get items or services of value by providing items of services of equivalent values, to a system where things are free? The current system would encourage a company who developed assemblers to hold onto those assemblers, and instead of selling systems that can produce wide arrays of products, just making the products and selling them. There is no incentive to sell such production machines, since they could be seen as sabotaging any future profit the company could make. "But they no longer need to make money" you can point out - but even today, people and companies that have all the money they need are still trying to earn more.

      If someone invented an assembler mechanism today, and started giving away machines that could make just about anything needed, society would collapse. Without a good path from here to there, it might be quite an unpleasant road.

      --
      "You know your god is man-made when he hates all the same people you do."
    25. Re:Raises interesting questions by drinkypoo · · Score: 1, Interesting
      Incidentally Ferrari already has cars you can't buy, you can only lease them. I believe the F50 is one of these cars. Not sure about the F40, I think some of those are privately owned.

      Rumor has it that they have a drive recorder in the car and if you don't drive it enough, and fast enough, then they terminate your lease. They want your ferrari out there kicking ass and taking names.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    26. Re:Raises interesting questions by Theodore+Logan · · Score: 0

      If it weren't obvious by the time stamp on your post that you didn't actually read the article, it is by the content.

      The questions you talked about were raised twenty years ago. If this article does anything, it is to cast doubt on the idea that molecular manufacturing is even possible at all, leading one to wonder if the questions you talk about are very pertinent. Ironically, the only reason you're two decades behind is that you tried to be a minute ahead with your ignorant post (which, of course, got a +5 anyway, as it related to the an issue that Slashdotters for some inexplicable reason can't get enough of).

      --

      "If you think education is expensive, try ignorance" - Derek Bok

    27. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      However, if molecular assemblers ever become mainstream I'd rather design my own car and let it assemble that.

      I'd hope that I was a mechanical engineer. I'd rather let an expert design the shiny box of thin metal powered by repeated gasoline explosions that flings itself down the pavement while surrounded by others just like it.

    28. Re:Raises interesting questions by Anonymous Coward · · Score: 0



      The assumption, however, is that companies will have any control over the technology. Once the technology exists, someone will duplicate it (perhaps using their corporate duplicator). It will then be out in the wild, and no corporation could stop it. Sure, they'll try RIAA-like tactics to keep it under control, but they'll be just as successful as they are today.

      Once every baby is fed, and everyone has a home no one will shed a tear for the corporations whining about how they're not richer than everyone else anymore. "All his son ever wanted for Christmas was his own private island in Micronesia. Thanks to illegal copying of music on the Internet, he might just not get it."

      Copyrights and other such laws do not stop illegal copying, they just give the appearance of a legal recourse.

    29. Re:Raises interesting questions by TheTick · · Score: 1

      Keep your closed-source Ferrari. I'll use my GPL diamondoid hovercar, thanks. Sure it's a little harder to drive and the seats aren't covered in leather, but the traffic sure is lighter up here at 150,000 feet...

      --

      --
      bachiatari na torisetsu o yome!

    30. Re:Raises interesting questions by Anonymous Coward · · Score: 1, Interesting

      At this point, we have the equivalent of Star Trek replicators and money is no longer an issue. So Ferrari wouldn't be "selling" anything because there wouldn't be anything you can give them that they can't already replicate themselves. Although I suppose, then, it's going to be a game of IP, as the shortage will no longer be of supplies but of services, like designing cars. So we will probably barter "assembler files" until there are enough open source versions that the common folk get what they need and the market collapses.

    31. Re:Raises interesting questions by Saige · · Score: 1

      I don't disagree that eventually, no matter what attempts the corporations may make, the assembler machines will get out. The key is that the corps are going to do everything they can to prevent it, and to make it as difficult as possible for the machines to be useful when they get out.

      Perhaps the feed stock systems they use will be made intentionally complex, something that is extremely difficult to duplicate, making any escaped machines nearly non-functional. Perhaps there would be internal mechanisms that react to broadcast signals inside the facility, and when the machines leave the signal, small explosives go off to destroy the interior mechanisms, making the interesting parts little more than useless rubble.

      And don't forget the lobbying for much stronger "intellectual property" protections that will be claimes as needed to protect the companies and their incentive for R&D. Considering the effect that removing/duplicating their machines could have, I could see such actions being treated even more seriously than credit card crimes are today.

      Don't forget, though, that in all of this, the machines will still need raw materials to manufacture objects. And there is no chance these raw materials will be free - at least in the forseeable future. If suddenly most people don't even have the option to work, due to so much being able to be created without human involvement, how do you pay for the raw materials?

      (Oh, and if you're in the mood for a seriously long-term investment, I'd consider purchasing a garbage dump. After all, when they develop molecular machines to the point that they can disassemble existing things, the dump becomes an ENORMOUS source of raw materials.)

      --
      "You know your god is man-made when he hates all the same people you do."
    32. Re:Raises interesting questions by misterpies · · Score: 1

      >> Ferraris are not IP, so you could copy it freely.

      I have a feeling the above post as meant to be funny but was somehow misunderstood. Anyway, its premise is totally, completely, utterly untrue. Any work is automatically copyright to its creator (or the creator's employer) the moment it is created. The only requirements are that it take some skill to create it and that its form is not dictated by purely functional considerations (that's what patents are for). It's a myth that you need to manually "copyright" a work.

      Ferrari will automatically have copyright in the design of the car, both as a whole and as parts right down to the steering wheel. Of course under fair use you might be able to reproduce parts of a ferrari, but to replicate the entire car is a clear breach of copyright.

      Of course, if you then try and sell your copied Ferrari, you'd also be liable for passing off and probably trademark infringement (if you copied the ferrari logo and/or name anywhere on the car).

      --
      The author of this post asserts his moral rights.
    33. Re:Raises interesting questions by anethema · · Score: 1

      Talk about thinking small-scale.

      If nano assemblers were common, money would no longer be even an issue. Copy a ferarri? who cares!

      The would would have the potential to become an instant utopia. Food could be made from anything, as long as the right atoms were available. A model could be made of anything. The prototyping costs for any idea you have could be zero. Technology would flourish. Starvation would dissapear. Probably some kind of population control would need to be put into effect, but ah well haha.

      No one would ever want for anything. Anything you could think of and maybe..draw in a 3d modelling program like solidworks or something, you could have, right away. It doesnt work right? make changes and watch it happen.

      Also,recycling would be 100% efficient, raw materials would almost never run out. When something gets old, throw it back into the heap of raw materials.

      You want a ferarri? fine..you wanna modify the engine to have 1000 HP? Also fine. Anything you want is at your finger tips..just wanting 'a cool car' is kind of small scale thinking.

      --


      It's easier to fight for one's principles than to live up to them.
    34. Re:Raises interesting questions by mooneyd · · Score: 1

      The design of a car is already covered by IP laws. Numerous parts are patented and the touch-feely stuff is covered by design patents and trademakrs. So it is already illegal to fabricate a Ferrari without permission.

    35. Re:Raises interesting questions by TheRaven64 · · Score: 3, Funny

      Make sure you run your downloaded design through some kind of malware detector, or you may find that you've just created a duplicate of the goatse guy...

      --
      I am TheRaven on Soylent News
    36. Re:Raises interesting questions by FunkSoulBrother · · Score: 1

      I get the feeling, that even if we made it peacefully into the era of molecular assemblers, that there would still be the rich and poor.

      Land, and the resulting, say, Iron atoms on it, would become extremely valueble. Of course with any luck the masses would outnumber the landowners by so much as to revolt and take whatever atoms they need, but I could see some jackasses trying it at least. ("Oh, you need GOLD for that computer you are trying to replicate? 15 cents an atom please.")

    37. Re:Raises interesting questions by gotan · · Score: 1

      There's already chips in some photocopiers to prevent ppl from copying money and some legal documents. Similar chips would be mandatory for molecular assemblers. Of course the customers would pay the extra necessary to support this scheme, first because the chips make the MA a little bit more expensive and second because the corporations selling the "ferrari-permit" (or whatever) have to license the "don't copy pattern". Come to thik of it you could put the "don't-copy-pattern" on the ferrari itself.

      It'd be just the same SNAFU as Macrovision in DVD-players (there's a special chip scrambilng your video if a bit is set on the DVD, and the DVD-Manufacturer pays license-fees to macrovision) and what some Idiots want to do to computers (trusted computing, so the content-sellers can trust our computers since they don't trust us).

      Of course there'd be a huge black market for MAs with just that chip ripped out and some corporation would sue Jon Johanson because he posted a description of circumventing the chip on the internet.

      --
      "By the way if anyone here is in advertising or marketing... kill yourself." -- Bill Hicks
    38. Re:Raises interesting questions by jafuser · · Score: 2, Insightful

      Money would not be much different from what we have now, except there will be no hard currency.

      Don't forget that land property will still have value in a replicator-enabled society. Energy will also probably need to be purchased.

      --
      Please consider making an automatic monthly recurring donation to the EFF
    39. Re:Raises interesting questions by gid-goo · · Score: 1

      Communism, that is what happens at that point. The idea being that there is no more scarcity of resources.

    40. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      Woah there, you manual labor monkey.
      Relax, we will leave couple of toilets for you to clean.

    41. Re:Raises interesting questions by BryanL · · Score: 1

      If you can copy the license certificate it might just be easier to copy the $200,000 to buy it. After all, you would be guessing what the license looks like, but $20 bills are easier to find.

    42. Re:Raises interesting questions by jchoyt · · Score: 4, Insightful

      Money will still have value. Someone has to create and/or design food, clothing, medicine, entertainment, etc. Money will buy what it has always bought - what is valuable. Over the last hundred years, we've gone from paying primarily for the stuff that makes up things, to paying primarily for people's time to manufacture things (i.e., labor is now more expensive than material). This would just complete that cycle.

      --
      Sometimes the truth is arrived at by adding all the little lies together and deducting them from all that is known.
    43. Re:Raises interesting questions by RLW · · Score: 1

      No need to get testy, jeepers. A playwright was meant to be an example of something that this type of invention couldn't touch. If such a device comes about it will eliminate nearly all manual labor based jobs and it will eliminate almost all jobs based on materials production (i.e. steel production). But that is nothing new, many manual labors have become obsolete because of the introduction of technology (the cotton gin, the steam engine, water powered mills, washing machines, automobile, etc.)Those who were affected negatively by this have historically had two choices. One complain about the de-humanization caused by the loss of jobs and be a victim or learn to do something else. It's easy to stand by the wayside claim victim status. Factor in computers and then 'thinking' jobs will be affected to. I write software for a living which to many seems like a good bet for a safe career (economic down turns not with standing) but some day there will be many natural language systems which will turn the everyday spoken word in to automated functions: I'm out of work. I will have to make this choice too. I made it a couple of times before as I used to do landscaping (interesting work but a nasty job during a Texas summer) and I've worked on an assembly line (utterly mind numbing there's no way I would go back to doing this unless it's the only way to provide for my family.)

      Society as a whole has had to deal with the consequences of worker displacement already. There was a time in the USA when a factory worker put in 12 hour days 7 days a week and at that barely made a living wage to support the family. Nobody wants to return to that. So eventually when there was enough social pressure (during the Great Depression) the 40 hour week was introduced. Yeah! Maybe the work week will shrink from 40 hours a week to 20 or 10. That would be great, I would love to spend that time doing other things besides earning a living. The thing to remember is this: virtually all jobs will be performed by machines at some point; that is if humanity stays the current course and we all manage to get along well enough not to kill each and every last one of ourselves. Along with this will come great social and economic upheaval. As everything becomes increasingly automated the cost of goods and services will drop dramatically. We'll have to make the value of human labor worth more and shorten the work week in order to properly restrict the supply of human labor. If done properly this will allow the average person an opportunity to make a decent wage *and* have more time to spend doing something enjoyable. The full benefits will not fully manifest for those caught in the transition but it will benefit those who come after.

    44. Re:Raises interesting questions by TheAntiCrust · · Score: 1

      Why couldnt computers write plays? Wasnt it chaucer or someone who said that there are only like 7 stories anyway? Couldnt a comuputer come up with new and interesting plot lines & twists? Add in some really advanced computer special effects and it can even direct, act, and produce a movie for you. It's really quite imaginable that technology will soon be able to do all the jobs humans currently do, and do them better and faster.

    45. Re:Raises interesting questions by kirkjobsluder · · Score: 1

      Personally, I suspect that the potentials for this technology are ovehyped. There are some pretty good reasons why it would be very difficult to make a copy of a car molecule by molecule that would still favor macro-scale production.

      To start with, there is the pesky problem of oxygen. It takes a pretty large quantity of energy to keep most metal ions from reacting. With traditional metalurgy and fabrication you gain the advantage that oxidation occurs at the surface. Working with individual atoms would make it difficult to construct a metalic object.

      In the end, it may just be cheaper (in terms of energy and time) to use macro-level fabrication techniques for anything bigger than a breadbox.

    46. Re:Raises interesting questions by Ralph+Wiggam · · Score: 2, Interesting

      Thank you for pointing out that by the time we can molecularly assemble something as large and complex as a Ferrari that the world will be a very different place.

      We will still have money, but we will buy different things. Information and services will still be scarce and need to be purchased. Also, the inputs for these assemblers will still have some scarcity. Obviously the biggies like carbon and oxygen aren't hard to get a hold of, but rare elements will be very valuable.

      Here's some free investment advice for the future. The first time someone publishes a successful assembler experiment, sell diamonds and buy gold.

      -B

    47. Re:Raises interesting questions by hurtstotouchfire · · Score: 1
      And you are quite likely correct.

      'Instant utopia' sounds a little terrifying to me. Besides, it'll be ages before molecular assemblers are accessible to anyone who can't already buy 16 ferraris to use as golf carts. So 'molecular manufacturing'(Drexler's new term) will be available and active for a long time before it's really available to the masses. They'll have a while to put together strategies for coping with licensing/copying issues. For a long time, molecular assemblers will be available only to the very brilliant and the very rich.

      And, of course, the rich and criminal.

      Incidentally, Drexler really sounds like he's got a ferrari up his arse.

      Smalley however, makes some excellent points. Enzymes and ribosomes can only work in water, and therefore cannot build anything that is chemically unstable in water. Halfway though building your ferrari molecule, it would not be stable, and it would probably just decide to grab some molecules off of all this convenient water. ...do you really think it is possible to do enzymelike chemistry of arbitrary complexity with only dry surfaces and a vacuum?

      So the main idea that Drexler is putting forward (although I'm sure he has many others) is using enzymes and ribosomes, which don't seem to be the best idea, because they only function in water, and I think we all understand why molecular assembly would need to be done in a vaccuum.

      If it[the nanobot] is a non-water-based life-form, then there is a vast area of chemistry that has eluded us for centuries.

      And then Drexler again (man, he's hateful)I'm glad you found my early work stimulating, and applaud your goal of debunking nonsense in nanotechnology. I hope that our exchange will result in broader discussion within the community, and in better understanding of molecular manufacturing as a strategic objective. blah blah blah my book etc etc...

      As far as I can tell, Drexler's comeback has to do with using stable molecules around the 'construction site' if you will. As molecules come together and react, their atoms (being "sticky") stay bonded to neighbors, and thus need no separate fingers to hold them. I'm not really buying it myself. Any Biotech people want to give some input?

      So it looks like our ferraris are far in the future. Smalley: Much like you can't make a boy and a girl fall in love with each other simply by pushing them together, you cannot make precise chemistry occur as desired between two molecular objects with simple mechanical motion along a few degrees of freedom in the assembler-fixed frame of reference.

      Sadly I agree with him. I haven't gotten the impression from this series that we're really all that close to having functional molecular assemblers. Does anyone know of a good article with a nice 'state of affairs' overview? This is what we can do, this is what we can't?

    48. Re:Raises interesting questions by Evil+Pete · · Score: 1

      Well in the era of Trusted Driving you will require an activation key to start your car delivered by Wifi to one only car. If more than one car requests it then none are supplied. Hmmm. Disturbingly that doesn't even seem like a joke. :(

      --
      Bitter and proud of it.
    49. Re:Raises interesting questions by EtherealSys · · Score: 1

      Forget the Ferrari. Give me a copy of the money he uses to buy it. Better yet, make it a couple copies.

      --

    50. Re:Raises interesting questions by Razor+Blades+are+Not · · Score: 2, Informative

      That's always good advice.

      1. Diamonds aren't that rare.
      2. DeBeers has created the artifical market for them we know of today - try selling those diamonds you just bought right back to the seller. He'll offer you a pittance if he'll even take them at all.
      3. Diamonds can be manufactured. We still can't turn lead into gold as yet (or even Uranium for that matter).

      Never invest in diamonds.

    51. Re:Raises interesting questions by RenaissanceGeek · · Score: 1

      If all MATERIAL goods may be replicated by the machine, then the only thing with value will be the inputs to the machine.

      Namely: ENERGY. (matter is all around us: even gold may be harvested from sea water in non-trivial (but non-profitable) quantities.)

      So, in a society with universal molecular manufacturing, the most valuable "posessions" in the future will be the sites of harvestable energy gradients(e.g. locations with abundant geothermal energy, or coastal locations adjacent to sharp thermal inclines.)

      In the future, the fundamental unit of currency may be the killowatt!

      --
      What is the difference between a small revolutionary change and a large evolutionary change?
    52. Re:Raises interesting questions by BorgCopyeditor · · Score: 1
      start to make improvements to the Tirrari

      Wouldn't that be Kferrari? Or maybe just Kar.

      The "improvements" would include basic features like a Kradio, KsteeringWheel, KbrakePedal, KrearViewMirror, ad nauseam.

      --
      Shop as usual. And avoid panic buying.
    53. Re:Raises interesting questions by RedWizzard · · Score: 1
      Buy with what money? When you can replicate all the food, clothing, shelter, weaponry, medicine, entertainment, and all the general goods you will ever need, what, exactly, is the point of money? Without scarcity, money ceases to exist in ALL it's forms... With a replicator, the entire CONCEPT of economics will go the way of the feudal system; just another quaint idea you can read about in your replicated bookery.
      What about land? That will still be scarce. You still need somewhere to put your replicated shelter. What about the raw material used by the replicator?
    54. Re:Raises interesting questions by femto · · Score: 1
      > Information and services will still be scarce ...

      Information is not scarce. Any scarcity is artificially created, by measures such as DRM and IP, in an attempt to turn information into capital and prop up existing economic systems.

      Indeed, one can generalise the entire 'Free Software' movement as an attempt to remove 'artificial scarcity' from information. Now you see why monopolists hate Free Software, as it threatens their entire power/wealth base.

    55. Re:Raises interesting questions by femto · · Score: 1
      And in the future, we will be paying for people's time to design things, as under this scenario assemblers will be doing all manufacturing.

      The thing is, a design is not a physical thing. No, the plans for an object are not a design. They are only an expression of the design. The actual design consists of ideas and concepts. How does one assign value to an idea? I would assert that it is impossible to do, as ideas spread from one mind to another, like a virus.

    56. Re:Raises interesting questions by UserGoogol · · Score: 1

      Yes, and energy would also be scarce.

      However, many extremely useful things can be produced just out of carbon, oxygen, hydrogen, and silicon, all of which are very easy to find.

      --
      "Never attribute to malice that which can be adequately explained by stupidity." -- Hanlon's Razor
    57. Re:Raises interesting questions by Feztaa · · Score: 1

      Obviously the biggies like carbon and oxygen aren't hard to get a hold of, but rare elements will be very valuable.

      I dunno, I think if we had the power to replicate a Ferrari from the component molecules, we'd also be able to replicate atoms/molecules from the component nucleons. So, if you needed some gold, you could just take apart some carbon atoms and put the correct number of protons/neutrons/electrons together to get gold.

    58. Re:Raises interesting questions by xmedar · · Score: 1

      It could be worse, you could get arrested for copying your freinds girlfreind, I think these two chaps need to settle this once and for all, a meeting in Copenhagen should do it.

      --
      Any sufficiently advanced man is indistinguishable from God
    59. Re:Raises interesting questions by ChreodeRiot · · Score: 1

      I've read articles about software that could learn your response reactions and then create music that you like by trying out diffferent melodies etc. and remembering what you like and putting the elements of what youlike together into songs. A more sophisticated version could weave plot elements and characters that you like (possibly with more sophiticated input from you) to create personalized novels for you.

      now here's the question! If you publish a story that was personalized for you, can you be sued by the creator of the software, and how would they be able to prove it was created by their software?!

    60. Re:Raises interesting questions by Anonymous Coward · · Score: 1, Informative

      In other words fusion. Strong force bonds are 10^40 times stronger than electromagnetic bonds.
      Femtotech (yes it already has a name)is significantly harder than nanotech.

    61. Re:Raises interesting questions by homer_ca · · Score: 1

      If nanotechnology could really bring such an age of abundance, we'd probably have a society or economy like Star Trek. In the game Alpha Centauri it was called Eudaemonia. With machines to do all the hard work, people would be free to pursue artistic or intellectual endeavors, and develop themselves to the best of their ability. The big problem here is motivation in the face of material abundance. Some people are naturally inclined to be artistic or intellectual. Then there's the rest of us who'd just turn into couch potatoes. Reality TV anyone?

    62. Re:Raises interesting questions by Guppy06 · · Score: 1

      "In other words, will I be arrested one day for making a copy of my friend's Ferrari?"

      Personally, I'm more curious about what would happen if you made a copy of your friend.

    63. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      You're not as smart as you think you are, you arrogant fucknut.

    64. Re:Raises interesting questions by penguin7of9 · · Score: 1

      Ferraris are not IP, so you could copy it freely.

      You're kidding, right? Car designs are already covered heavily by trademarks and patents. Auto companies sue each other over something as trivial as the approximate shape of the headlights.

    65. Re:Raises interesting questions by FiloEleven · · Score: 1

      So why not just make a copy of the license to make a license?

    66. Re:Raises interesting questions by d3faultus3r · · Score: 1

      the point is that everyone can acquire what they want or need. If designers could get all the things they wanted anyway, so how would one compensate them for their ideas?
      Plus, money would be valueless, owing to the fact that you could not purchase anything tangible with it and you could simply create identical copies at will, effectively creating infinite inflation.

      --
      read my blog
      musings on politics and technol
    67. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      Whatt??? no hard currency!!!! what are you smoking?

      There will be no paper, or fiat currencies - they could be made by anyone.

      There will be no (physical) stock certificates, bonds etc, they could be made by anyone. (e-money? No. although it will probably exist, it will not be money. just fancy IOU's)

      What about gold coins? they could be made by anyone, true, but they would have to have some gold feedstock for their molecular assemblers. Gold can't be duplucated, only found (mined extracted) or possibly manufactured from other substances via nuclear processes. (nano assemblers don't do that !!!)

      What about iron bars? the bars could be made by anyone, true, but that requires iron feedstock ...

      What about water? that can be made easily now, hydrogen, oxygen, spark, some way to capture the vapor. but you need hydrogen and oxygen to do it, and nano assemblers won't change that.

      I think that you get the point.( if not, again what are you smoking? I want some!)

      What is Money?? try this article

      With widespread nanoassemblers, stuff will become money. Probably some kind(s) of rare elements (or compounds that are hard to make via assemblers) that are important feedstocks for making stuff. Non-rare ones would not work well simply because of the bulk of material (it's value/(volume+mass) ratios or something similar)

      All of you proclaiming the end of economics are ignorant of economics. Economics will end when people end, or can easily and simply break the conservation of matter/energy on a massive and personal scale (ie. in my backyard, or smaller). Or when people end. whichever comes first.

    68. Re:Raises interesting questions by blincoln · · Score: 1

      It is most certainly *not* illegal to build any car from parts, or even to make one car look like another.

      Actually, it is illegal to copy the design of a car.

      Ferarri, for example, has used their legal department against people selling replicas of their cars.

      The kit car industry seems to be like the replica prop industry - the IP owners don't go out of their way to bust people who make unlicensed products, but if they do take notice they will shut them down.

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    69. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      How does one assign value to an idea?

      The same way you do with everything else: (1) put it up for sale and see what people will pay, influenced by (2) how much it cost you to produce the design, instead of doing something else.

      When you buy a book, you're not paying primarily for a bunch of paper glued together. You're paying for the ideas therein.

      Yes, Virginia, there is such a thing as intellectual property.

    70. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      Information is not scarce.

      Malarky.

      Information that has already been produced, discovered, assembled, etc. and digitized, is not scarce for long, because the costs of copying it are extreamly low. (barring copyrights, laws etc. unnatural restraints)

      Information about planets outside of our solar system is very scarce. very litle is known beyond some exist. DRM and IP have almost nothing to do with this scarcity. This is the kind of information thet will always be scarce, and (some) people will be willing to give up assets ( things of value!) for this kind of scarce information.

      I know this is slashdot, but please people try to think a little bit. Information is more than source code, binaries and MP3's. those are merely specific examples of copyrighted information.

    71. Re:Raises interesting questions by femto · · Score: 1
      Agree with your second paragraph (Information that has...).

      I suspect we have different definitions of 'information'. I generally take 'information' in the sense of information theory: bits. In this context, scarcity of information translates into scarcity of bits. Knowledge can be translated into bits, so on this basis, I claim human knowledge is not inherently scarce.

      Scarcity of information, as you describe it, is a very subjective concept. Is information on a subject 'scarce' because what is unknown exceeds what is known? On this basis, it could be claimed that we know very little in the scheme of things, therefore all information is scarce. Perhaps this is true and all knowledge really is a rare thing to be treasured. Unless information we restrict ourselves to what is known, I think we can argue either way on this one until we go blue in the face.

      Perhaps scarcity of information is really about the proportion of the population who know a piece information? In that case, if ten people know something what gives nine of them the right to stop the tenth from telling another person (apart from mob rule)? In my view, this is the crux of IP and DRM. Depending on whether you think you can morally force people to keep secrets your stance on IP/DRM will vary.

      Look at scarcity of information in this way, IP and DRM can have a lot to do with information about planets and solar systems. What if NASA claimed copyright on all their pictures, applied DRM to them and restricted their distribution to select few, who have all signed NDAs? What if all their papers were under the same regime? What if every scrap of data from every space probe was sealed up in the same way? What about text books? I can keep going until every source of knowledge is covered. Now we are striking at the heart of human endeavour and learning.

      I will acknowledge that these arguments are not without holes, but I think they are a reasonable effort and right now I can't afford to spend more time on them.

    72. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      Take a look at the growth of the free software community - something of very high complexity is being done for free. I can notice a few facts about it:

      1. it's being done mostly by university students, because they still have free time and are being provided for by their parents... with replicators, you enable people of all ages to participate, go about doing things that interest them, at which they are also far more efficient than work, where few end up doing what they really want to

      2. software - because you only need a computer to develop. You can't see as much development/design/engineering in other fields of technology (i.e. Ferraris), because one needs expensive equipment that only labs of big companies have. When you have the ability to replicate this equipment...

      Dunno about the existence of money, but definitely not because research/engineering would require it!

    73. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      Dumbest post ever.

    74. Re:Raises interesting questions by fitten · · Score: 1

      I think he was joking.

    75. Re:Raises interesting questions by jafuser · · Score: 1

      I don't see this as being practical in the future, where more and more financial transactions are becoming electronic.

      If you look back in history, you can see that there's a problem with metal currency which has inherent value in it's composed material -- people would shave little pieces off of many coins to accumulate enough of that metal to be worth something. After some time, many coins were much smaller than their original minted state.

      To cut down on this activity, everyone could carry a scale with them to weigh the metal they are transacting.

      But another potential scam would exist to skirt this - people could create counterfiet metals by mixing in or plating over other heavy metals. So now you have to check density as well? And how hard will it be for counterfieters to find the right mix of metals to spoof the density, especially using nano-assembling technology?

      I doubt we will regress back to using inherent-value hard currency in the future, especially given how quickly society is giving in to electronic transactions that leave very little room (if any) for counterfieting.

      --
      Please consider making an automatic monthly recurring donation to the EFF
    76. Re:Raises interesting questions by dreamchaser · · Score: 1

      You'll still need energy to run the replicators...perhaps the joule will be the unit of currency of the future, or credits based on a 'joule standard'.

    77. Re:Raises interesting questions by robslimo · · Score: 1

      Raw material for all those assemblers would become the currency... and MicroDirt Corporation will have cornered the market.

    78. Re:Raises interesting questions by jchoyt · · Score: 1

      But you still need raw material. You still need services. An awful lot of money is spent that never buys anything tangible - just ask any consultant. Money doesn't just buy tangible things - it buys people's time.

      If there is no money - no basis for trade - who're going to be the waitresses and cab drivers of that future? Why would people do all the design work in the first place? Why would people do dangerous jobs? RedHat has made a business of selling something they have to also give away for free. Why? One of the major reasons is the convenience they provide - you no longer have to go build your own Linux system.

      There are many, many uses for money other than buying food, clothing, and shelter.

      Jeff

      --
      Sometimes the truth is arrived at by adding all the little lies together and deducting them from all that is known.
    79. Re:Raises interesting questions by Anonymous Coward · · Score: 0

      >> who're going to be the waitresses and cab drivers of that future?

      Who needs a waitress when your table dispenses the food?
      Who needs a cab driver when cars, trains, and planes are automatic?

      >> Why would people do all the design work in the first place?

      Perhaps because they want something better for themselves, which just happens to benefit others as well. I can also imagine that AI will be advance to the point where we can simply ask it questions and give it instructions, and it will do the design work for us.

      >> Why would people do dangerous jobs?

      They might not. With advanced technology, these jobs might become far less dangerous, or be done by robots.

      In the end, I think the only currency will be that you get someone to do something only by offering to do something for them in return.

  2. Lest we forget by carl67lp · · Score: 4, Interesting

    Richard Feynman talked about nanotechnology way back in 1959--before "nanotechnology" was even a word.

    It kind of irks me that the person who coins a word gets more credit than a person who talked about the actual process--nearly thirty years prior.

    Read Feynman's talk at the Zyvex Web site.

    1. Re:Lest we forget by Anonymous Coward · · Score: 0, Informative


      Richard Feynman talked about nanotechnology way back in 1959

      **bzzztt!* Wrong. Feynman was actually talking about nanobiology - the differences between the two are subtle, but distinct Yes, he did propose the possible usage of organic materical as "a relay for information" but that is where the similaties end. I can understand how they appear the same on a surface level, but please get your facts straight before spouting.


    2. Re:Lest we forget by belrick · · Score: 3, Informative

      You're the one who doesn't know what he was talking about. He literally described using machine tools to make 1/2-size versions of themselves, then using those ones to make 1/2-size versions of them, and so on. He then argued about the scale down to which you could do that.

    3. Re:Lest we forget by kasparov · · Score: 4, Interesting
      Actually, in the above mentioned Feynman lecture, There's Plenty of Room at the Bottom, Feynman talks about making machines that make smaller machines that make smaller machines that make... you get the picture. From the above lecture:
      Why can't we manufacture these small computers somewhat like we manufacture the big ones? Why can't we drill holes, cut things, solder things, stamp things out, mold different shapes all at an infinitesimal level? What are the limitations as to how small a thing has to be before you can no longer mold it? How many times when you are working on something frustratingly tiny like your wife's wrist watch, have you said to yourself, ``If I could only train an ant to do this!'' What I would like to suggest is the possibility of training an ant to train a mite to do this. What are the possibilities of small but movable machines? They may or may not be useful, but they surely would be fun to make.
      He was not only talking about nanobiology.
      --
      There's no place I can be, since I found Serenity.
    4. Re:Lest we forget by Anonymous Coward · · Score: 0

      Feynman may well have "invented" nanotech but Drexler "innovated" it....
      (well at least by current popular language usage)

    5. Re:Lest we forget by scsinutz · · Score: 3, Informative

      Granted. Feynman theorized that it could be done. He made a $1000 bet to his students that they could not construct a working motor 1/64 of an inch square -- He lost this months later when a student was able to produce it. Feynman was disappointed because he figured that the technology needed to get construction down to the molecular level would have sprung forth from his little grassroots project. This is where Drexler and Feynman differ.

      The main difference between Feynman and Drexler, (and why Drexler deserves to have an equal share of the limelight) is Drexler is a more responsible scientist.

      I highly recommend you stop on over to the Foresight Institute website [foresight.org] and see what Eric Drexler has been responsibly been working on for the past 20 years. There's an online version of Engines of Creation [foresight.org] available in which Drexler examines the hopes and dreams of Nanotech, minus the onesided utopia/distopian slant. Drexler has always been an advocate for technology to be developed by responsible hands (whoever that is) and asks Should We? as well as Could We?

      I think this novel humanitarian approach to groundbreaking scientific development is a bit refreshing, don't you?

      Chris McAllister
      --
      =Cheers! Chris McAllister
    6. Re:Lest we forget by Christopher+Chang · · Score: 1

      The problem with such an approach is that it assumes "we" have a monopoly on R&D.

      Unless we have the power to prevent anyone else from developing whatever we consider forbidden, and we are willing to use that power, we will merely delay development, and we'll eventually fall victim to "If we outlaw X, only criminals will have X".

    7. Re:Lest we forget by Noren · · Score: 1
      In what way was Feynman less responsible than Drexler?

      Unlike Drexler, Feynman typically responded to valid criticism of his work. Drexler ignores a glaring problem which was pointed out and instead rehashes a tired summary of a method which has just been shown to be flawed. That's real scentific irresponsibility, and lip service to the topic of avoiding possible negative uses of the science will not change that.

    8. Re:Lest we forget by tgibbs · · Score: 1
      It kind of irks me that the person who coins a word gets more credit than a person who talked about the actual process--nearly thirty years prior.

      Drexler has always been at pains to credit Feynman; indeed, he cites Feynman in the letter exchange referred to in the article. I can remember ever seeing a general article on the subject that did not begin with Feynman. On the other hand, despite being an early visionary, Feynman never really pursued the serious development of nanotechnology. It remains to be seen whether Drexler's contributions to the field will be more substantive than Feynman's, but at minimum he deserves credit for reviving interest in the subject at a time when the technology is mature enough to make some real progress. Even Smalley credits Drexler for getting him interested, even though he doesn't buy the rest of Drexler's vision of the future of nanotech.

    9. Re:Lest we forget by Anonymous Coward · · Score: 0

      Nobody's who RTFA is going to forget that, as he is duly credited by Drexler. And nobody in the freakin world has gotten more credit than Feynman for this. As another poster said, I can't even remember when I read a piece on Nanotech that didn't begin quoting that talk. It's probably one of the most famous talks in the history of science.

      So, get off your high horses and

      READ
      THE
      FUCKING
      ARTICLE


      Idiot.

    10. Re:Lest we forget by NanoGator · · Score: 1

      "It kind of irks me that the person who coins a word gets more credit than a person who talked about the actual process--nearly thirty years prior."

      Let history remember Gene Roddenberry as the inventor of the transporter!

      --
      "Derp de derp."
  3. Kurzweil by Ragelic · · Score: 5, Informative

    Also interesting is Ray Kurzweil's comments on the exchange:

    http://www.kurzweilai.net/meme/frame.html?main=/ ar ticles/art0604.html

    1. Re:Kurzweil by Anonymous Coward · · Score: 1, Informative

      Let's try that again:
      here it is

  4. Well... by mirko · · Score: 2, Insightful

    Even if they are not possible, I suspect by studying a way to make these possible, one may find out something interesting so, let's pretend these are possible...

    --
    Trolling using another account since 2005.
  5. Yum by grub · · Score: 5, Funny


    How long would it take one of these assemblers to make a cup of "Tea, Earl Grey, Hot"?

    --
    Trolling is a art,
    1. Re:Yum by sznupi · · Score: 2, Funny

      or "Bomb, Hydrogen, 20 megatons"

      --
      One that hath name thou can not otter
    2. Re:Yum by Anonymous Coward · · Score: 0, Funny

      Or "Catherine Zeta-Jones, naked, wet."

    3. Re:Yum by amightywind · · Score: 1

      How long would it take one of these assemblers to make a cup of "Tea, Earl Grey, Hot"?

      This is modded as funny but it raises a significant point. The atomic world is not rigid at all scales. Atoms can diffuse, dislocate, etc. Thermal motion and entropy must be considered. How can a deterministic molecular assempler allow for these?

      --
      an ill wind that blows no good
    4. Re:Yum by Anonymous Coward · · Score: 0

      Stephen King, 56, dead.

    5. Re:Yum by bkhl · · Score: 1

      Why Earl Grey when you can go for a nice black cup of Lapsang Souchong?

    6. Re:Yum by Anonymous Coward · · Score: 0

      BSD, old and busted, dying

    7. Re:Yum by clambake · · Score: 1

      I'm sure it wouldn't take long, however I am sure it would be almost, but not entirely, unlike tea.

    8. Re:Yum by AJWM · · Score: 4, Funny

      The risk, of course, is ending up with something almost but not completely unlike tea.

      Especially if your replicator is another fine product of Sirius Cybernetics.

      --
      -- Alastair
    9. Re:Yum by dillon_rinker · · Score: 1

      I can get this substance from my friendly nearby hot-drinks vending machine. There is the faintest hint of tea in the tepid murky water it dispenses, and I have often commented that it is almost, but not entirely, unlike tea.

    10. Re:Yum by Yanray · · Score: 1

      It depends on how long it takes a person to explain to the computer the history of tea, tea drinking, the British East Indian Company, and the correct size/composition of the two "lumps".

      I miss DNA

      --
      --"Sorry for the inconvience." Gods Last Words to his Creation
      DNA, So Long and Thanks for all the Fish
    11. Re:Yum by Anonymous Coward · · Score: 0

      "Base, all your, belong to us."

    12. Re:Yum by Anonymous Coward · · Score: 0

      Because that's what Captain Picard drinks. A better answer would be 'who gives a fuck?'

    13. Re:Yum by Anonymous Coward · · Score: 0

      "Nanobot overlords, I for one, welcome."

      (why does Picard suddenly talk like Yoda when ordering tea, anyway?)

    14. Re:Yum by bkhl · · Score: 1

      I certainly do. Lapsang Souchong is the queen of teas. Earl Grey isn't even pure tea.

  6. Forceful language indeed by worst_name_ever · · Score: 1
    From the summary:

    You don't get it. You are still in a pretend world where atoms go where you want because your computer program directs them to go there. You assume there is a way a robotic manipulator arm can do that in a vacuum, and somehow we will work out a way to have this whole thing actually be able to make another copy of itself.

    Wow. If I talked that way to my corporate overlords I'd be kicked to the curb. Maybe I should have been a scientist!

    --

    In Soviet Rush, today's Tom Sawyer gets high on you.
  7. Tinkering with nature by Anonymous Coward · · Score: 0, Troll

    I am certainly impressed with the progress made in the nanotechnology field. Our research lab (which is currently located in south Israel) has been making some studies in the same field. We have invited several world-renowned scientiest to work in our lab. While I'm not actively involved in the said research, I'm responsible for the data warehouse that collects the data into a FoxPro cluster.

    One published paper presented the idea of creating a 2.4GHz transmitter in a nanobot which would provide a life feed to the chiropractor when he/she is trying to rehabilitate an athlete. We found that western patients were problematic, since the high content of lead in their bodies scrambled the information sent.

    The one thing we are doing is sharing our information. We're currently working on a research portal so that fellow scientist can access our data quickly instead of receiving it on ancient 5.25 floppy disks.

    Which is nice.

    1. Re:Tinkering with nature by Effugas · · Score: 4, Insightful

      No offense, but what idiot thought to use 2.4ghz inside the body?

      Yes, of course it barely transmits, 2.4ghz is the frequency used by microwaves to heat food, because water absorbs it so well.

      Hint: We're mostly water too.

      Now if we could just dessicate people utterly, those transmitters would work just fine...wouldn't be much of a life monitor, though...

      --Dan

    2. Re:Tinkering with nature by RLW · · Score: 1

      Uh yeh, if lead is the culprit then your patents are suffering from plumbism. You need to have them contact a medical doctor as they are suffering from gastro intestinal problems and damage to their nervous systems. Also 2.4 GHz in the human body is a bad idea as you will also be slowly cooking your subjects with microwaves. There is some really bad research going on here.

    3. Re:Tinkering with nature by Anonymous Coward · · Score: 0

      Did you read the parent post? It's actually a bit amusing (data warehouse on a FoxPro cluster, etc.). Why don't you put yourself on the waiting list for a funny bone transplant?

    4. Re:Tinkering with nature by carn1fex · · Score: 1

      Yea i designed and built a transmitter that would go onto the backs of laboratory rats that would monitor their brainwaves via implanted electrodes. I figured i would be FCC compliant and use the free for all 2.4GHz band (800Mhz wasng big enough). Only after it was built did i realize i would slow roast the rat.. i said it was gunna die anyways cuz its a lab rat pumped full of drugs and its brain was exposed to the air, but they said it might 'skew the data' or some crap. Bastards.

      --

      ---------

      No matter how thin you slice it, its still baloney.

    5. Re:Tinkering with nature by mnmlst · · Score: 1

      Hey, you must be the same Dan "Effugas" who wrote the Appendix on cryptography in the back of a Check Point study guide I have used a LOT. Nice to see you actively Slashdot!

      --
      In principio erat Verbum.
    6. Re:Tinkering with nature by Anonymous Coward · · Score: 0

      You are, of course, right. Insightful like a ton of bricks... :)

      --Dan

  8. I can see what the problem might be by Dunark · · Score: 2, Interesting

    There is a fundamental obstacle to creating moleular assemblers: What do you make them out of?

    Imagine that you were given the task of designing a machine to lay bricks. This probably would not be all that difficult, considering all of the things we already do with robots.
    However, the problem becomes much more difficult if I add the stipulation that the machine be constructed entirely from bricks and mortar.

    1. Re:I can see what the problem might be by Anonymous Coward · · Score: 0

      There has already been research into using DNA as machines to build things. They've been able to create DNA 'machines' that could theoretically lead to building the molecular assemblers that will be able to place atoms precisely.

      And in fact, molecular assemblers already exist in nature. Ribosomes read DNA and then build protein molecules with more fundamental parts. Another belief is that ribosomes could possibly be used to read customized DNA and build the first real man-made molecular assemblers.

    2. Re:I can see what the problem might be by ArmenTanzarian · · Score: 1

      It also needs to be able to create brick and mortar brick-and-mortar-laying-machines that are microscopic and water based life forms.

    3. Re:I can see what the problem might be by hey · · Score: 4, Insightful

      Try to make a C compiler out of C while you are at it. Oh yeah...Already done!

    4. Re:I can see what the problem might be by Zathrus · · Score: 5, Insightful

      By your logic we don't exist. After all, how could a human have been born without a human to bear it?

      But good job on restating the chicken and egg problem in an obscure way.

      The first molecular assembler can be built "by hand", just like the first robots were. We've already got the capability to shove around individual atoms (remember IBM spelling out "IBM" with Xenon atoms?), so it's at least theoretically possible (as long as we only need Xenon atoms to build it at least ;) ).

    5. Re:I can see what the problem might be by DrEldarion · · Score: 2, Insightful

      The thing is that you have to have the building blocks to start with. In your example, for instance, a very basic C compiler was created in assembly language, then the rest of the compiler was created with that small one. Relatively easy now, but of course somebody had to create the assembler, and somebody had to create the processor, etc. etc.

      Getting the building blocks becomes a lot harder when you're in new territory and don't have as much to work with.

    6. Re:I can see what the problem might be by HeghmoH · · Score: 2, Interesting

      Replace "bricks" with "cells", and you have just made all life impossible. We know that self-replicating machines are possible, because we are surrounded by them everywhere all the time. It may be difficult, but it is obviously not a "fundamental obstacle".

      --
      Mod down posts with a "Free Mac Mini/iPod" sig, they're spam!
    7. Re:I can see what the problem might be by Dunark · · Score: 1

      And in fact, molecular assemblers already exist in nature.

      That is true, but those assemblers are not general-purpose: They are only capable of constructing certain kinds od molecules, and cannot be used to create completely arbitrary molecules.

      The difficulty is that the "tool" is part of the chemical environment: You can't grab an atom without forming bond(s) to that atom, and doing that alters the way that atom interacts with other atoms. The detailed structure of the tool must be compatible with the molecule you wish to build, and that creates a chicken-and-egg problem: How to you build the tool?

    8. Re:I can see what the problem might be by Anonymous Coward · · Score: 0

      Your point would make more sense if you knew what you were talking about.

    9. Re:I can see what the problem might be by Dunark · · Score: 1

      Try to make a C compiler out of C while you are at it. Oh yeah...Already done!

      I think that's a flawed analogy, because the machine the C compiler needs to execute it can be built without any need for a pre-existing C compiler, and we can build that machine in a manner that ensures it will be possible for it to execute the C compiler.

      We don't have such a luxury when building molecular assemblers. The "machine" we run on isn't under our control: It's the particle interaction laws nature stuck us with, and nobody has yet proved those laws admit the design of a general-purpose molecular assembler. Maybe it can be done, but I think it's going to be a long, slow process.

    10. Re:I can see what the problem might be by Waffle+Iron · · Score: 1
      Imagine that you were given the task of designing a machine to lay bricks. This probably would not be all that difficult, considering all of the things we already do with robots.

      However, the problem becomes much more difficult if I add the stipulation that the machine be constructed entirely from bricks and mortar.

      It gets harder:

      Imagine that you were given the task of designing a machine to make meat. This probably would not be all that difficult, considering the consistency of most "meat" found in fast food restaurants.

      However, the problem becomes much more difficult if I add the stipulation that the machine be constructed entirely from meat.

    11. Re:I can see what the problem might be by MajikGuru · · Score: 1

      If you want to make an apple pie from scratch, you must first create the universe. - Carl Sagan

    12. Re:I can see what the problem might be by Dunark · · Score: 1

      I didn't say "impossible". I said "Much more difficult".

    13. Re:I can see what the problem might be by Dunark · · Score: 1

      The first molecular assembler can be built "by hand", just like the first robots were. We've already got the capability to shove around individual atoms (remember IBM spelling out "IBM" with Xenon atoms?), so it's at least theoretically possible (as long as we only need Xenon atoms to build it at least ;) ).

      I don't think that first molecular assembler will be truly general-purpose, but rather will be capable of building only a limited variety of molecules. I think we're going to have to build a hell of a lot of primitive assemblers "by hand" before we have enough basic tools to tackle more complicated assemblers, and that many iterations will be needed before general assembly can be tackled (it might not be possible).

    14. Re:I can see what the problem might be by dutky · · Score: 1
      Dunark wrote:
      Imagine that you were given the task of designing a machine to lay bricks. ... the problem becomes much more difficult if I add the stipulation that the machine be constructed entirely from bricks and mortar.


      Now, imagine that the bricks come in several hundred shapes and sizes and the mortar can be formulated to produce a wide range of strength and fexiblity.

      Atoms are not bricks and atomic bonds are not mortar. Analogies are only good for very specific and limited tasks: if taken too far (as you have done with your bricks & mortar = atoms & atomic bonds analogy) they breakdown and lead to misleading, if not outright ridiculous, conclusions.

    15. Re:I can see what the problem might be by bradbury · · Score: 1
      You make them out of the same elements that biological or semiconductor components are made out of. I.e. C, Si, B, N, P, O, S, H, F, and Cl. See Nanosystems Section 9.5.2c (you need to do you homework before you post to /. -- or sometimes you might get kicked to the curb :-)). The problem of designing machines from completely higher level descriptions has been addressed in part by the DEMO group at Brandeis. Their machines were designed from something as simple as LEGOs.

      In general it sounds as if you are unfamiliar with the topic and the methods required to solve the problems involved.

      Robert

    16. Re:I can see what the problem might be by Doom+Ihl'+Varia · · Score: 1

      A cow produces meat. It is made entirely of meat. Easy task. Do I get paid for this one?

    17. Re:I can see what the problem might be by Dunark · · Score: 1

      Now, imagine that the bricks come in several hundred shapes and sizes and the mortar can be formulated to produce a wide range of strength and fexiblity.

      OK, so make can make bricks and mortar that are suitable for convenient assembpluy. Now, how do you fabricate atoms having convenient properties? The last time I checked, the properties of atoms were dictated by laws of nature that we don't yet completely understand and have no clues whatsoever about how to change.

      Your criticism has flaws comparable to the ones you point out in my analogy.

    18. Re:I can see what the problem might be by Kaki+Nix+Sain · · Score: 1
      A cow is not made entirely of meat. If you ever saw one, you obviously weren't paying any attention at all. If you had paid attention, you would have noticed things like hair, skin, hooves, eyes, and teeth (plus a great deal of other non-meat things inside).

      --

      (C) Kaki Sain, 2011. By reading this, you have illegally copied my property to your brain.

    19. Re:I can see what the problem might be by Anonymous Coward · · Score: 1, Insightful

      So what you're saying is that because you don't control the instruction set, it's impossible to build a C Compiler? Dang, I wonder how Watcom, Microsoft, Borland et al manage to do it when others (Intel, AMD, HP, IBM) control the instruction sets. Hmm, perhaps the analogy is not invalid after all?

      In the universe's instruction set, biological compilers use a small RISC subset of the available instructions (atomic interactions). Not all the instructions may be usable by an atomic compiler, but that doesn't mean the biological instructions are the only ones that will work in any atomic compiler. Drexler's and Smalley's arguments basically boil down to arguments about which instructions are usable and controllable. That's an answer that can only be answered by more research; yet Smalley seems to ignore some of the research already done in this area, which makes his arguments weaker, though not insignificant.

      The thing is the analogy is not an existence proof, it's a counterexample that the claimed counterproof is invalid. Which is why you admit a general-purpose assembler may be possible. Um, so what was your point again?

    20. Re:I can see what the problem might be by BLAMM! · · Score: 1

      It's not a problem at all. The bot simply needs to be an order of magnitude (maybe 2) larger than the materials its working with.

      Your analogy of a bricklayer made of bricks is not valid because bricks are not made to be moving parts. A Lego-Bot designed to build with Legos is more accurate, and I would hope, easily understood by the /. crowd. Certainly its not an easy task, but not impossible either.

    21. Re:I can see what the problem might be by Dunark · · Score: 1

      So what you're saying is that because you don't control the instruction set, it's impossible to build a C Compiler?

      No, I didn't say impossible. Also, any computer that you are likely to run a C compiler on probably has an instruction set that was designed for general-purpose computing. I'll bet it's a lot harder to port a C compiler to other kinds of chips, such as digital signal processors or the GPU chips found in high-end graphics cards.

      All I'm trying to say is that we didn't have any say in the design of the particle interaction laws that would comprise the instruction set of the machine that executes our molecular assembler, and that those laws may make building a true general-purpose assembler difficult or impossible.

    22. Re:I can see what the problem might be by sulaco252 · · Score: 1

      Who says eyes aren't meat?

      --

      (There used to be something clever here.)

    23. Re:I can see what the problem might be by FiloEleven · · Score: 1

      I'll be convinced when Lego builds a Lego factory out of Legos.

    24. Re:I can see what the problem might be by Grizzlysmit · · Score: 1
      The first molecular assembler can be built "by hand", just like the first robots were. We've already got the capability to shove around individual atoms (remember IBM spelling out "IBM" with Xenon atoms?), so it's at least theoretically possible (as long as we only need Xenon atoms to build it at least ;) ).
      I don't think that first molecular assembler will be truly general-purpose, but rather will be capable of building only a limited variety of molecules. I think we're going to have to build a hell of a lot of primitive assemblers "by hand" before we have enough basic tools to tackle more complicated assemblers, and that many iterations will be needed before general assembly can be tackled (it might not be possible).

      Yeah we need to build the tools to build the tools, but at least there's some positive signs that maybe it can be done (yn).

      I think we'll do it, but it'll be some what different to what we expect. I cannot prove any of that though, but neither can the anti-mob.

      --
      in my life God comes first.... but Linux is pretty high after that :-D
      Francis Smit
    25. Re:I can see what the problem might be by niftyzero · · Score: 1
      I don't think (at least initially) assemblers will be putting things together atom-by-atom. It's much more likely that they will be fed pre-fabbed molecules.

      The advantage of an assembler is that you can put together the feedstock molecules in complex, pre-programmed patterns.

    26. Re:I can see what the problem might be by niftyzero · · Score: 1

      I believe the plan was to pre-fab molecules with suitable properties, not atoms.

  9. Whats in a name? by +MG · · Score: 1

    Molecular assembler? Surely you mean Matter Compiler? Or emcee.

    I can't be the only person to have read the Diamond Age.

    1. Re:Whats in a name? by Anonymous Coward · · Score: 0

      >I can't be the only person to have read the Diamond Age.

      Yes. Yes you are.

    2. Re:Whats in a name? by mnmlst · · Score: 1

      What I want is one of those robotic horses (a chevaline) and a Kevlar duster-type coat. That would make me a Cosmic Cowboy of the Future. Wait, would that make me Cowboy Neal?

      Let's not even start talking about the Mouse Army among these rogues on Slashdot... Thousands of teenage Asian girls, oh boy.

      --
      In principio erat Verbum.
  10. Comment removed by account_deleted · · Score: 2, Interesting

    Comment removed based on user account deletion

  11. Assembler by termos · · Score: 0, Offtopic

    The Gnu ASsembler ought to be enough for everyone.

    --
    Note to self: get smarter troll to guard door.
    1. Re:Assembler by BinLadenMyHero · · Score: 0, Offtopic

      Dumb moderators..
      I found that funny.

    2. Re:Assembler by AKAImBatman · · Score: 1

      The Gnu ASsembler ought to be enough for everyone.

      I despise the GNU AS syntax. Sure, it may be more "standard", but it's very difficult to read and keep track of. NASM syntax is much, much nicer.

  12. From the article: by Steve+'Rim'+Jobs · · Score: 5, Funny

    In lectures and in a September 2001 article in Scientific American, Smalley outlined his scientific objections to the idea of molecular assemblers, specifically what he called the "fat fingers problem" and the "sticky fingers problem."

    Aye, this is something that almost all /.ers have had to face at one point or another.

    1. Re:From the article: by G-funk · · Score: 1

      "The fingers you have used to dial, are too fat. To obtain a special dialling wand, please mash the keypad with yout palm now."

      --
      Send lawyers, guns, and money!
  13. Not a good idea ! by plinius · · Score: 1

    Hasn't anyone learned from the warnings issued by K Eric Drexler or even Michael Crichton? Will we jump headlong into creating tiny machines with the only aim being making money and doing something "cool"? Technology people are so predictable, maybe what's needed is to station a psychology on every street corner in areas where nanotech is being done and pay them to remind people to have a conscience and grow up a little.

    1. Re:Not a good idea ! by Saige · · Score: 1

      Yes, learn from Michael Crichton. That any technology will inevitably be used by people in ways that will cause it to break down or go haywire in various ways that break the laws of nature yet make for exciting movie plots. But somehow when everything goes wrong, events will happen to allow them to cover it all up so nobody knows it happened.

      Yes, his books can be entertaining. But taking fiction that appears to be grounded in science, and breaking various physical laws to make the story more interesting only serves to misrepresent what can happen. Prey takes his dramatic licence to quite the extreme - there are plenty of critiques on the book around demonstrating that Crichton seems to be less and less interested in actual science as time goes on.

      --
      "You know your god is man-made when he hates all the same people you do."
    2. Re:Not a good idea ! by plinius · · Score: 1

      Then read K Eric Drexler's "Engines of Creation", available in any library, for a more serious treatment of the huge risks that nanotechnology brings.

    3. Re:Not a good idea ! by Saige · · Score: 1

      Believe me, I've read EoC a couple times at least. At least Drexler doesn't go all over-dramatic with his depictions of the dangers that molecular nanotechnology does present - and offers some suggestions for ways to address those issues.

      I would just never suggest using fiction to demonstrate the drawbacks to a technology unless it is exceptionally well-done and scientifically accurate. Which Crichton is not.

      --
      "You know your god is man-made when he hates all the same people you do."
    4. Re:Not a good idea ! by kirkjobsluder · · Score: 1

      Yes, learn from Michael Crichton...

      Write novels that read like they were novelizations of screenplays?

      A good argument as to why this can't happen is that we have had self-assembling critters around for a few billions of years. And yet, basic constraints of chemistry and physics have prevented the development of a "green goo".

  14. required reading by Rxke · · Score: 3, Informative

    84-page peer-reviewed white paper on nanofactory. Conclusion: we see no hurdles, predicted time line: 10 years from now we could haave the first operating assembler... http://www.jetpress.org/volume13/Nanofactory.htm

    1. Re:required reading by Anonymous Coward · · Score: 0

      "Grammarnazis puhleezz have mercy with us nonnatives "

      Only when you antigrammarnazi morons quit fucking equating the pursuit of accurate and elegant speech with Nazism.

    2. Re:required reading by Rxke · · Score: 1

      Just using 'grammarnazis' because it is a widely accepted term in the /. community, you know... and you fail to see the point. Non-natives are regularly modded down by people like you (?) simply because their English isn't perfect. Eloquence is sometimes a great way to veil ignorance. Bad grammar doesn't necc. mean you're stupid or a phillistine(sp?)

    3. Re:required reading by Hal-9001 · · Score: 3, Insightful

      A disclaimer: www.jetpress.org is the website of the Journal of Evolution and Technology, published by the World Transhumanist Association. Upon skimming the contents, it's more like a cultural studies journal like Social Text than a scientific journal like Physical Review, so it may or may not be correct about all the scientific details.

      --
      "It take 9 months to bear a child, no matter how many women you assign to the job."
    4. Re:required reading by Rxke · · Score: 1

      Agreed. They're more a 'what ll the socaleconomic problems be' but the artcle itself ve seen beng referred to on several places, so guess t's knda ok......

    5. Re:required reading by pmj · · Score: 1

      Yeah, "peer-reviewed". By who, exactly?

      Published by the World Transhumanist Association. That inspires LOTS of confidence that it's not a bullshit "journal". Gimme a break.

      I'd also like to point out that Chris Phoenix has a Masters in Computer Science. Not physics, biology, chemistry. Nothing that relates to the kind of physical science you need to truly appreciate what is happening at the nanoscale.

      I am far more inclined to believe a Nobel Prize-winning Chemist than a nanotech enthusiast.

      --
      Are you BioCurious?
    6. Re:required reading by Anonymous Coward · · Score: 0

      Well fine, if you're not interested in learning anything better than pidgin English, if all you can do is lash out at the few people left who are willing to teach it (notice I never said anything about modding anything), then you can just wallow in your own apathy. Ignorance indeed.

    7. Re:required reading by iawia · · Score: 1

      The article is originally from CRN, run by Chris Phoenix, of which Erik Drexler is on the board of directors.

      It does not describe the structure of a molecular assembler, but is a reasonably detailed exploration of how a nano-factory, capable of building diamandoid structures and machinery, could be build once a molecular assembler is available.
      It does describe a few directions in which people have had ideas for different approaches to creating molecular assemblers, though. And it's an interesting read if you want to see how people have seriously been thinking about ways to create MNT.

    8. Re:required reading by Anonymous Coward · · Score: 0

      'Nigger' used to be a widely accepted term too.

    9. Re:required reading by Anonymous Coward · · Score: 0

      Ahhh... but there's the rub... according to many (*cough*Linux zealots*cough*) enthusiasts are better at many things, like writing code, than people who actually know what they are doing based on training and experience.

  15. Love and Molecular Assemblers by ericspinder · · Score: 2, Interesting
    I think that I got most of the arguments, but it's hard to take a stand. I especially liked this "counterpoint" quote:
    Much like you can't make a boy and a girl fall in love with each other simply by pushing them together, you cannot make precise chemistry occur as desired between two molecular objects with simple mechanical motion along a few degrees of freedom in the assembler-fixed frame of reference. Chemistry, like love, is more subtle than that. You need to guide the reactants down a particular reaction coordinate, and this coordinate treads through a many-dimensional hyperspace.

    *sigh* I'm touched.

    Also I found it interesting that the usage of Nanotechnology was changed so greatly that the creator of the term accepts the newer phrase 'molecular assemblers' for that process.

    --
    The grass is only greener, if you don't take care of your own lawn.
    1. Re:Love and Molecular Assemblers by Anonymous Coward · · Score: 0

      What, so you have to get the molecules drunk?

    2. Re:Love and Molecular Assemblers by ericspinder · · Score: 1
      What, so you have to get the molecules drunk?

      Oddly enough, one of Smalley's main points is that to produce the enzyme or ribosome entity the nanobot would need to have a liquid core. So I quess the answer is "yes, you would need to get them drunk!"

      --
      The grass is only greener, if you don't take care of your own lawn.
  16. Smalley == Nanotechnology by mnmlst · · Score: 0

    With a name like Smalley, I can see why this guy went into nanotechnology. Now I understand why Dr. Karl Maxxum was the chief architect of the Empire State Building;)

    --
    In principio erat Verbum.
    1. Re:Smalley == Nanotechnology by Anonymous Coward · · Score: 0

      Well, look on the bright side-- he could have been named "Dr. Shrinker."

      Now THERE's a guy who's been pigeonholed by his name. "Hmm, what should I do for a career? Psychiatry, or reducing people to the size of mice??" :)

  17. It's The Snack Food, Stupid! by tds67 · · Score: 3, Funny
    Drexler thinks "molecular assemblers" are possible while Smalley denies it.

    They are possible, and Twinkies(TM) provide the proof. They are manufactured with absolutely no nutritional value whatsoever, and this is only possible if vitamins and minerals are screened out at the molecular level.

  18. DNA by MindStalker · · Score: 2, Interesting

    They say its impossible, but isn't DNA essentially just that, and I'm quite sure some lab recently built a transitor from DNA so I'd say its definatly possible.

    1. Re:DNA by sznupi · · Score: 1

      which btw shows, IMHO, pottential risk involved in nanotechnology - DNA can do it, but think of all possible mutations, cancer, etc. - I wonder what would be the result of such "process errors" in case of nanotechnology

      --
      One that hath name thou can not otter
  19. Grey goo by Space+cowboy · · Score: 1

    Looks like good ole Prince Charles can relax for a while yet then...

    I find it sort of reassuring that a technology as potentially fantastic (and therefore treated with immense enthusiasm) has to undergo a long period of maturation before people can even agree on the basics...

    Simon

    --
    Physicists get Hadrons!
  20. Well, I read the letters by panurge · · Score: 5, Interesting
    I'm not a nanotechnologist but I have had a fair bit to do with the behavior of atoms on surfaces, especially metals. I think that Smalley seems to have a much closer grasp on the real world than Drexler. The idea of a nanobot twisting a pi-bond here and snapping a sigma-bond there seems quite ludicrous; where such reactions occcur in the real world it is because of the properties of the exact molecules involved and is reaction-specific. You can't just say "well, this works with an iron atom in a hemoglobin molecule, so let's make a different carrier molecule with the same geometry, put it on a robot arm and use it to collect up nickel atoms, or whatever". Biology works because over billions of years a limited group of reactions has been found to work on a limited range of materials, in bulk and in carrier liquids. The notion that this means you can just build little tiny cranes and waggle atoms around does not follow.

    From reading the letters I don't think Drexler has really addressed the problems raised by Smalley fingers at all, he just tries to brush the problems aside.

    --
    Panurge has posted for the last time. Thanks for the positive moderations.
    1. Re:Well, I read the letters by bradbury · · Score: 1, Informative
      Read Chapter 8 of Nanosystems -- "Solution-phase synthesis and mechanosynthesis". I doubt Smalley has. Then go compare Drexler's CV with Smalley's CV. While Princeton is a good school it is *not* MIT. And even if Smalley were smarter than Eric, something I greatly doubt, Smalley would still have to go up against assertions by Feynman (a Nobel prize recipient like Smalley). So on a reputation basis Smalley cannot trump Drexler and Feynman.

      With regard to the hemoglobin molecule example this is precisely the problem that Smalley has -- a lack of knowledge. There are at least 3 other examples of a porphyrin ring carrying an atom other than iron known in nature. So it seems perfectly reasonable to structure alternative carriers. Yes, all possible tool tips will not work as expected. But the that does not mean that all possible tool tips will fail as well. The notion that mechanosynthesis will not work seems to contradict current chemical methods where chemical reactions occur by random interactions between atoms/molecules. If these aren't random mechanical interactions then I must misunderstand chemistry.

    2. Re:Well, I read the letters by MarkusQ · · Score: 5, Insightful

      You can't just say "well, this works with an iron atom in a hemoglobin molecule, so let's make a different carrier molecule with the same geometry, put it on a robot arm and use it to collect up nickel atoms, or whatever". Biology works because over billions of years a limited group of reactions has been found to work on a limited range of materials, in bulk and in carrier liquids. The notion that this means you can just build little tiny cranes and waggle atoms around does not follow.

      Let's see how well that argument stands up in paraphrase:

      You can't just say "well, this works with a bird in the sky, so let's make a different wing with the same shape, put it on a vehicle and use it to fly around, or whatever". Animal mobility works because over billions of years a limited group of structures has been found to work on a limited range of environments. The notion that this means you can just build airplanes does not follow.
      No one is suggesting that we would blindly copy the geometry of some biological mollecule (without regard to it's charge distribution, orbital occupation, potentials for resonences, etc.), attach it to a robot arm, and expect it to do the job, any more than we would build an airplane by glueing birds wings on a school bus.

      The whole biological-existence-proof line of arguments came up because some people (including Smalley, IIRC) claimed that building macroscopic objects out of components assembled with atomic precission was impossible in principle. Life forms are a clear concrete example of something that is build in exactly that way.

      Now, saying that birds exist does not tell you how to build an airplane (though birds might be a good place to look for hints); all it does is shoot a big hole in the argument that flight is impossible.

      -- MarkusQ

    3. Re:Well, I read the letters by iawia · · Score: 5, Insightful

      "From reading the letters I don't think Drexler has really addressed the problems raised by Smalley fingers at all, he just tries to brush the problems aside"

      If you'd read the letter a little more closely, you would have seen that Drexler didn't address the problems with those 'sticky fingers' because he'd thought of the problems a long time before smalley, and had thus dismissed that idea a long time ago.
      The worrying thing is that Smalley found it necessary to use an already dismissed idea as a straw man to try and make Drexler look bad. Not very scientific. And certainly not conductive to the advancement of science.

      From other's (I'm neither a physicist, chemist or biologist) reactions on Smalleys technical arguments, I gather that his understanding of proteins is 20 years outdated, since that's how far back it was proven that proteins can function outside of water.
      Biology works because when it found one reaction that worked, it stuck with it and developed it further. If something is not demonstrated in biology, that doesn't mean it can't exist. Conversely, if something is demonstrated in biology (and as Drexler argues, that is true for molecular assemblers), we know it's possible.

      The idea of a making and breaking chemical bonds with molecular precision has already been demonstrated. That it won't work with every combination of molecules is a given. But then, it's very difficult to drive a nail into a wall if your hammer is knitted out of wool, and the nail made of rubber.

      The bottom line in this debate is that Drexler, and with him many others, believe this is a promissing direction for research. Unfortunately, Smalley is the one holding the purse (he's with the NNI), and doesn't want any research in that direction.

      Drexler talks about being prepared, Smalley about not worrying the children. Regardless of who is right on the science side, what do you think is the wiser decision?

    4. Re:Well, I read the letters by Saige · · Score: 3, Informative

      If you just read the exchange of letters, well, it does appear that Drexler does not properly address some of Smalley's points. Drexler points out that "fingers" are not needed, that there are other mechanisms for guiding the molecules to their reaction point. But he never elaborates on what these mechanisms are, nor addresses Smalley's issue about molecular reactions not being as simple as assembling Lego bricks.

      I suppose if I finished reading my copy of Drexler's Nanosystems, I'd see more information about proposed methods of directing molecules and getting the desired reactions, but it's still not there in these letters.

      Smalley is making one hell of a claim though, going from criticizing Drexler for not having clearly articulated (to his satisfaction) the methods of molecular assembly, to claiming that molecular assemblers are impossible. As Drexler points out with the quote from Smalley - when a scientist claims something is impossible, they are more than likely incorrect.

      I understand Smalley's perspective, by trying to dissuade fears of runaway nanomachines and the like - but that doesn't mean Drexler's idea is wrong, but that the idiots that assume any nanomachine invented will instantly start replicating itself and turning the planet into grey goo. There's a higher likelihood of humanity being wiped out by a meteor impact, nuclear war, or the appearance of a super-virus than the grey goo occuring.

      --
      "You know your god is man-made when he hates all the same people you do."
    5. Re:Well, I read the letters by ghutchis · · Score: 4, Insightful

      I'm sorry, that's irrelevant. That's like saying someone told a false statement because he's a Republican. (Take your pick on insult you'd like to throw.)

      I could be a bum on the street and still tell you the correct science. You might not believe me, but it's still correct.

      As for Mr. Drexler, I've read Nanosystems. Mr. Drexler doesn't know chemistry. If he did, he could tell me all the cool new reactions we need to create the stuff he proposes. Or the chemistry/physics needed to do a nanoassembler.

      I've done plenty of computational chemistry research--it's about 90% of my Ph.D. And you know what? I can happily draw whatever molecule I want on the screen and predict the properties. Can I make it?

      NO, not necessarily!

      There's a reason a lot of people hate orgo class in college. Chemistry is tough--there are a lot of exceptions and the best synthetic chemists have years upon years of experience in lab bumping their heads against walls trying to make things.

      Drexler needs to try some synthetic chemistry. Maybe then he'll rethink his nanoassembler idea.

    6. Re:Well, I read the letters by ghutchis · · Score: 1

      The notion that mechanosynthesis will not work seems to contradict current chemical methods where chemical reactions occur by random interactions between atoms/molecules. If these aren't random mechanical interactions then I must misunderstand chemistry.

      Oh sorry, I forgot to rebut your point about "random mechanical interactions." If you take mechanism classes, you'll find out that 95% or more of chemical reactions are quite intricate. When you're working on 10^23 molecules, you can win--some of those will line up correctly and go through. Some won't.

      Drexler works on the scale of *ONE* assembler at a time. What does it do if it doesn't have the orbitals in the "tip" aligned correctly? How does it make sure that pathway goes through in a given time?

    7. Re:Well, I read the letters by Noren · · Score: 3, Insightful
      The man has a Nobel Prize and you're worried about what school he got his PhD from? Yeesh. And Feynman certainly didn't give Drexler a 'Drexler is always right, even 15 years after my death' card. Why the focus on intellectual dicksizing?

      No, chemical reactions don't happen like that. Molecules do not randomly appear in product positions, nor do they follow nice straight lines to form products. They follow complicated, n-dimentional reaction coordinates involving deformations of both product and reactant. Drexler mumbles something about mechanical arms and ignores this point. Using a different name for something that is functionally identical to a "Smalley Arm" does not mean that you can cavalierly ignore all the problems which have been shown to exist for a "Smalley Arm".

    8. Re:Well, I read the letters by trixillion · · Score: 1

      You, sir, are the worst kind of fool.

      BTW, you do know where Feynman recieved his Ph.D., don't you? Here's a little hint, it starts with a 'P' not an 'M'.

      Hey, Mods, this guy should be (-1:troll).

    9. Re:Well, I read the letters by Popadopolis · · Score: 1
      I agree that it can't really be alchemy, and you almost certainly have more experience in the field than I do, but since atoms and molecules combine and change and just do stuff naturally, could they then be manipulated by humans to do what we want them to do? I mean, it is (theoretically) possible to change the properties of molecules. It is done all the time for, say, drug companies. They spend years of research and work to make new molecules that may (or may not) do what they want.

      All I am saying is that it is still technically possible. It may be impractical now, but it can be done.

    10. Re:Well, I read the letters by Anonymous Coward · · Score: 0

      Unfortunately you are applying to broad a stroke by assuming an assembler would require chemistry; This was Drexler's point.

    11. Re:Well, I read the letters by bradbury · · Score: 1

      Well, we have a claim of knowledge from "authority". Not too much different from the claims that Smalley seems to make. I would ask the questions of (a) what fractions of molecules that can be created by retrosynthetic chemistry programs actually fail during the synthesis process? and (b) are the "failures" of the form that the desired chemical reactions do not take place or simply that they do not take place in quantities required to make the production process efficient? Because one has the problem -- if one can produce even a single molecular assembler and if it is able to produce a wide variety of products with a precise moleculular structure (something I will admit is open to debate) then your objections would seem to be on swampy ground. So this transitions from a chemistry problem (low efficiency of the reaction) to a biological problem (how can I select the precise molecular product which fits the design specifications -- something antibodies are very good at).

    12. Re:Well, I read the letters by Noren · · Score: 1
      I like your airplane example- early attempts at flight did attempt to emulate the motions of birds' (and other flying animals') wings, and they were all unsuccessful. Fixed wing aircraft (a design quite unlike how birds fly) turned out to be what would actually work for man, unlike the natural example.

      No one is saying that you can't do chemistry to make small molecules. But the existance of a biological enzymes does not mean that the very different process of putting molecules together with "molecular machinery" will work. (or "Smalley arms" or whatever the current buzzword for a mechanical method is)

      The biological case works because all the other interactions not at the site are favorable, often attracting the two molecules with hydrogen bonding and electrostatic interactions- enzymes are therefore very specific, and work to do one reaction(or, occasionally, a few very similar ones.) Drexler thinks he can ignore all the other interactions to make an unreactive assembler work in a general case, but Smalley has shown that these other interactions are too large to ignore.

    13. Re:Well, I read the letters by ghutchis · · Score: 1

      OK, you ask some good questions. I'm going to replace your "retrosynthetic chemistry programs" with "a really good synthetic chemist." Right now, my friends in synthetic chemistry research aren't worried for their jobs because there are a few programs that attempt retrosynthetic analysis. It's really, really hard stuff. (Ask any orgo student.)

      (a) I think what you're asking is something like this... If I draw an arbitrary molecule on paper that looks like it's chemically plausible (i.e. no bonds to helium atoms), how likely is it that *some* synthesis could make that molecule?

      I don't know the answer. I don't know if anyone does right now. Chemists don't usually work that way. We pick specific targets, not arbitrary ones.

      But I'd guess the answer is "maybe 80%" or more just can't be made under standard conditions. Chemistry is good at making molecules, but a lot of things I see are actually made under inert atmosphere, no water, high pressure, etc. Even ignoring that, there are plenty of examples in the chemical literature of a target molecule that no one seems to be able to make, period, even though they seem plausible. (So let's say "50%" can't be made period.)

      Octanitro-cubane is a great example. It was finally made last year or so, after something like 10 years of research, several lab explosions and a few grad student injuries. (I think someone lost fingers.)

      And in my research, I've done QM calculations on molecules that are certainly plausible. But as it turns out, adding group X to that part of this known molecule makes this bond here pretty weak and so the whole thing isomerizes into a more stable form.

      Take cases where you have two chemically similar molecules called "tautomers." It's hard to know which one is more stable and they often interconvert. Even good chemists do some work and realize that the isomer they want will always convert to the other form.

      Bonds rotate. Bonds vibrate. A lot of chemistry happens inside a molecule itself--a hydrogen moves or a double bond changes orientation. Yuck!

      Anyway, that's a few things that can happen chemically that can stop you from making an arbitrary molecule. That's why good chemists have great job security. :-) Oh, I didn't mention that it's a broad enough field that if I drew molecule X, I might not have the experience in these types of molecules to have the slightest clue how to do it. Synthetic chemists focus on one very small area in grad school so they can at least be good on a few types of reactions.

      (b) Ah... Certainly you're correct that a lot of reactions just have crummy yield and require a lot of purification. So if we had this magical nanoassembler, new products could be made. And we'd probably learn more mechanisms--our current techniques don't reveal much on this length scale and mechanistic chemistry can have some "hand waving" explanations for some reactions.

      But there are plenty of cases I've had myself, when a supposedly perfect reaction should work and simply does not produce the product you expect (if it produces anything besides tar). Talk to a synthetic chemist and you'll find that they sometimes run the same reaction a few times with different results.

      Put simply, some bonds just don't seem to be possible. And we don't know why.

      You back off of some claims I've heard from Drexler's camp when you say "wide variety of products." See, we probably can make a "wide variety" of molecules--we already do that in lab! But a "wide variety" is a far cry from being able to design an arbitrary diamondoid nanogear.

      I honestly think that after a few hundred years of synthetic chemistry, the fraction of things that we can make, relative to the molecules I could draw on paper is still quite small.

      (Full disclosure, I would describe my research as nanoscience and I think the field has lots of promise.)

    14. Re:Well, I read the letters by ghutchis · · Score: 1

      Fair enough. But what else are you going to use?

      Chemistry, broadly defined, has always been about making molecules.

      I won't argue that Drexler hasn't been influential or that he hasn't raised interesting problems. But I stand by what I said.

      How do you create an arbitrary molecule?

    15. Re:Well, I read the letters by Anonymous Coward · · Score: 0

      Jimmy Carter has a Nobel Prize too. Receiving a Nobel Prize is not directly dependent on one's intelligence or Ivy League pedigree.

    16. Re:Well, I read the letters by BigBadBri · · Score: 1
      Regardless of what Carter's Nobel prize was for, unless your IQ is in the high 160s, and you've had a lifetime of experience, then Carter is probably a good deal smarter than thou.

      --
      oh brave new world, that has such people in it!
    17. Re:Well, I read the letters by Anonymous Coward · · Score: 0

      Jimmy Carter has a Nobel Peace Prize. Don't be an ass!

    18. Re:Well, I read the letters by MarkusQ · · Score: 2, Insightful

      Drexler thinks he can ignore all the other interactions to make an unreactive assembler work in a general case,

      He most clearly does not. He thinks (and, as I've stated, I think he's correct) that these are engineering problems and not "basic science" problems. No one is saying they can be "ignored" anymore than they would say that things like drag can be ignored when designing an aircraft. But that doesn't mean (as Smalley seems to conclude) that the whole thing is impossible, anymore than the existence of drag makes aircraft impossible.

      There are lots of potential unwanted side reactions, just as in any field of engineering, and there are lots of ways to deal with them, just as in any field of engineering. But you'll never get anywhere if all you do is throw up your hands and say "Look, complications! We're dombed to failure!"

      -- MarkusQ

    19. Re:Well, I read the letters by Pentagram · · Score: 1

      Hasn't everyone had a lifetime of experience?

    20. Re:Well, I read the letters by Noren · · Score: 1
      Well, the claims made as to the abilities are grandiose- he's postulating general use machines.

      If you have to craft a designer molecule to do each reaction, you're just doing classic chemistry. We've been doing that for decades, if not centuries. Calling it 'nanotechnology' is just confusing the issue. (There have been interesting things on a nanometer scale coming out of the Chemistry community- but they're called macromolecules, and they don't require nonexistant materials to make 'positional controls' out of.)

    21. Re:Well, I read the letters by MarkusQ · · Score: 1

      Well, the claims made as to the abilities are grandiose- he's postulating general use machines.

      Yes. In the same way that computers are general use machines. They don't do everything (e.g., computers don't wash windows), but they are still very, very handy.

      If you have to craft a designer molecule to do each reaction, you're just doing classic chemistry. We've been doing that for decades, if not centuries. Calling it 'nanotechnology' is just confusing the issue. (There have been interesting things on a nanometer scale coming out of the Chemistry community- but they're called macromolecules, and they don't require nonexistant materials to make 'positional controls' out of.)

      You're missing the point. You have to design each part of the general purpose machine (just as all the parts of a computer have to be designed), but then you have your general purpose machine.

      Suppose I said "computers aren't worth developing because they can't do everything imaginable, and to make them work right you'd have to design every part--which is just electrical engineering and doesn't justify the grandiose claims Turing is making for his so-called computer. It's still just electronics, and calling it 'computer science' is just confusing the issue."

      As late as 1950 or so I might not have gotten laughed out of the room, but today almost anyone would say I was a nut.

      -- MarkusQ

    22. Re:Well, I read the letters by Noren · · Score: 1
      You're missing the point. You have to design each part of the general purpose machine (just as all the parts of a computer have to be designed), but then you have your general purpose machine.
      You're missing the point. atoms interact with each other quite strongly at that scale and ALL atoms are 'fat' and 'sticky' at that scale. You can't just sweep that under the rug with 'we'll develop it ones which aren't'. Engineering can't change the fundamental properties of atomic interactions.

      Biological systems get around this by NOT being generic, but instead lining up large numbers of atoms to form weak bonds all around the atoms to be transferred. Large sections of the two molecules must pair up precisely for this to happen.

      You can hypothetically do this for any specific reaction by designing a specific molcule to do that reaction, analogous to the way nature does it. But doing specific chemical reactions like this is classic chemistry, and is not what Drexler is claiming to be developing.

      There is no instance in nature of a 'generic' enzyme which works without forming any interactions with the surroundings of the active site... which is what Drexler is claiming is possible, but which Smalley claims is impossible.

    23. Re:Well, I read the letters by trixillion · · Score: 1

      As an Ivy Leaguer, I have to ask. What the hell does having an Ivy league pedigree have the do with anything? If you are enrolled in one, then you need to get over yourself and your narcisism and realize that the overwhelming majority of very smart people in this country do not and did not attend one of those institutions. There simply are not enough slots and too many well-connected, not-so-smart people out there.

      Let's see:
      280MM Americans.
      Assume the average American is 40, then we can estimate the typical class size at 7MM students. The 7 Ivies have maybe ~70k american undergrad students combined. So that's about one slot for every 400 american students. Do you really think that the typical Ivy student is in the top .25% of all american students in intelligence? From experience I'd say, closer to top 10%. But that would mean that for every 1 Ivy student there are 80 non-Ivy students in america who are just as smart. Got it, 80 to 1, think about that. No matter how much you move my figures around you aren't going to end up anywhere near 1 to 1. For graduate students its a little closer, because there are maybe 3x as many grad students at Ivies as undergrads and from my experience they are more like top 5% of population in Ivy grad school (at least in my program.) Still that leavs a ratio of more than 10 to 1.

      As much as I have benefited from the Ivy myth, I wish that people would get a clue.

    24. Re:Well, I read the letters by MarkusQ · · Score: 1

      First off:
      1. No one is suggesting developing new atoms.
      2. No one is intending to change the fundemental properties of atomic interactions for engineering. Quite the contrary, the claim is that these properties can be used.
      3. 'Fat' is a matter of scale; anything is 'fat' at a small enough scale.
      4. Not all combinations of atoms are sticky under all conditions, and not all combinations of atoms that are sticky are equally sticky.
      5. There is nothing magical about "generic" vs. "specific" devices. A computer is a generic device, each part of which is designed to do a specific task. You can make something that is very generally useful by combining a finite number of parts of limited usefulness.
      6. Generic/specific is a matter of degree. While there is no catalyst that promotes all reactions (if such a concept is even cogent) there certainly are catalyst that are more or less specific, in terms of the range of reactants that they work with.
      7. While the fact that something exists in nature proves that it is possible, the converse is not true. There would be little evolutionary reason for the formation of "generic" enzymes, and I can think of good reasons for not evolving them.
      That said:

      We both claim the other is missing the other's point. I think your point is that it would not be a simple undertaking, and may well be beyond our capibility for the foreseeable future. My point is that this does not mean that it is impossinble, which is what Smalley appears to be claiming.

      -- MarkusQ

    25. Re:Well, I read the letters by Crazy+Eight · · Score: 1

      Touche.

    26. Re:Well, I read the letters by bradbury · · Score: 1

      I agree with much of what is said by ghutchis. Organic chemistry is a very messy business and there is a lot that is still unknown (also will admit that my organic chemistry experience is limited to several quarters of education so there is much I may be unaware of).

      What I think will happen is that chemists working on things like mechanosynthesis with AFMs or similar devices will develop simple reactions that they are comfortable with that are known to work (just as perhaps organic chemistry developed). At the same time biologists and biochemists will understand an increasing set of reactions that are accomplished by enzymes as the structures and mechanisms are worked out. This will eventually lead to the design (or perhaps directed evolution) of enzymes that work with different substrates, elements, etc. The combination of these will ultimately provide the toolkit that is needed to begin something like the assembly of a nanogear. I am hopeful that it will not take a few hundred years because companies that demonstrate robust nanoassembly abilities are likely to be very successful so there is a fairly large financial benefit to those who figure out how to do this.

    27. Re:Well, I read the letters by danila · · Score: 1

      How do you create an arbitrary molecule?
      Well, you take a scanning tunneling microscope, you take enough atoms to build a copy of this molecule, you design it and check that it is stable. Then you start building it atom by atom - you take an atom with a STM, you move it to the correct location and you place it there. This is long and tedious, but it can be done. Of course, there are much easier ways to do it, like design a chemical reaction that builds this particular molecule out of simple ones, which can be made in bulk.

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    28. Re:Well, I read the letters by danila · · Score: 1

      How many building blocks are needed to create millions of lifeforms (millions of trillions [?] of organisms) that can populate an Earth-class planet? You'd be surprised to know that the answer is "less than 100". How many building blocks are needed to create basically everything that we might need and imagine? While optimisation might sometimes require synthesis of advanced and rare molecules, it sounds plausible that "less than 1000" might be correct...

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    29. Re:Well, I read the letters by danila · · Score: 1

      While Princeton is a good school it is *not* MIT.
      Read Part 2 of Surely You're Joking, Mr. Feynman! - "The Princeton Years". I doubt you had. Then you will realise how Feynman himself compared Princeton and MIT. :)

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    30. Re:Well, I read the letters by Noren · · Score: 1
      4. Not all combinations of atoms are sticky under all conditions
      This is false at the relevant scale. Read the article.

      We're arguing in circles because the claim is either impossible if it's a mechanical method (because there exists nothing with the properties required), or an old method dressed up with a fancy new name if it's all about calling catalytic chemistry 'nanotech'.

      Choose one and stick with it- I'm tired of having to swap back and forth between the two.

    31. Re:Well, I read the letters by Goldsmith · · Score: 1

      You've got it backwords.

      In the nanotech field, Drexler is seen as someone who is good with the media and the government, and occasionally says the right thing. Smalley is one of our gods.

      The rest of the world might see it differently, but that Nobel counts a hell of a lot to us.

      By the way, you do misunderstand chemisty. Chemical reactions are definitely, definitely NOT do to "random mechanical interactions." I think a score of physical chemists have just keeled over in shock!

    32. Re:Well, I read the letters by MarkusQ · · Score: 1

      I read the "article," what there was of it. No where did I see Dr. Smilley claiming to have discovered new physics to do away with van der Waals forces (which are repulsive at that scale). Nor do I see an explanation of why, if all repulsive forces between atoms have been abolished at any given scale we don't see a universe holding a single blob of atoms that are stuck together by this unaviodable stickiness of yours.

      What I did see is the same old strawman claim that Drexler is suggesting a manipulator arm to control each atom (which is idiodic on the face of it) rather than the actual proposal to mechanically bring a series of carefully designed tools (surfaces with the desired catalytic effect) into play as needed. This is neither impossible nor just "a fancy name for catalytic chemistry" which does not offer any where near the control.

      -- MarkusQ

    33. Re:Well, I read the letters by Noren · · Score: 1
      No where did I see Dr. Smilley claiming to have discovered new physics to do away with van der Waals forces (which are repulsive at that scale).
      This is, of course, false- they're attractive at that distance, and don't become repulsive until the atoms are much closer than this. Why are you making this stuff up?
      What I did see is the same old strawman claim that Drexler is suggesting a manipulator arm to control each atom (which is idiodic on the face of it)
      Well, if you'd RTFA you'd see Drexler's claim that:
      Machine- and solution-phase chemistry share fundamental physical principles, yet differ greatly. In machine-phase chemistry, conveyors and positioners (not solvents and thermal motion) bring reactants together. The resulting positional control (not positional differences in reactivity) enables reliable site-specific reactions.
      I don't know if I'd go as far as calling it idiotic, but it's what's being claimed by Drexler. "Conveyors and positioners" sounds like a not-very-subtle renaming of a "manipulator arm" to me.
    34. Re:Well, I read the letters by MarkusQ · · Score: 1
      No where did I see Dr. Smilley claiming to have discovered new physics to do away with van der Waals forces (which are repulsive at that scale).
      This is, of course, false- they're attractive at that distance, and don't become repulsive until the atoms are much closer than this. Why are you making this stuff up?
      Who's making stuff up? To me it looks like you are. Yes, they are slightly attractive at larger distances, but they are repulsive when you get clos enough to form bonds, and much more repulsive than they are atractive further out.

      If you insist on an example of universally repulsive forces, how about like charges?

      "Conveyors and positioners" sounds like a not-very-subtle renaming of a "manipulator arm" to me.
      I'm starting to suspect that I've been taken in by a very clever troll (dispite the fact that I've had you on my "friends" list for quite a while).

      If all "conveyors" and "positioners" are "manipulator arms" and therefore impossible, then Smalley's position is in real trouble. An conveyor could be as simple surface with a regular array of active sites which could be "charged" (or activated) by something as simple exposing them to an excess of the moity to which they bind. A positioner is just something that moves things with respect to each other.

      So are you claiming that Smalley thinks:

      1. Surfaces are impossible?
      2. Adsorbtion is impossible?
      3. Catalytic surfaces are impossible?
      4. Moving things is impossible?
      -- MarkusQ
    35. Re:Well, I read the letters by Saeger · · Score: 1
      Thanks for the entertaining argument you two. :)

      It's this centuries version of the heavier-than-air flight debate, but with much, much greater implications.

      In any case, we'll know who's right very soon, because "The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom." - Feynman

      --

      --
      Power to the Peaceful
    36. Re:Well, I read the letters by Noren · · Score: 1
      Who's making stuff up? To me it looks like you are. Yes, they are slightly attractive at larger distances, but they are repulsive when you get clos enough to form bonds, and much more repulsive than they are atractive further out.
      You are. Your claim that van der Walls forces are repulsive on the nanotech scale is either just made up, or you're lying. It's looking more and more like the latter. To get to the repulsive region of the van der Walls surface you have to go all the way through the attractive part, so unless you're claiming they're actually forming bonds the fact that a repulsive part of the potential energy surface near the covalent radius exists (but which they'll never reach) is irrelevant.

      The very least reactive element known is helium. You can't get any less sticky than that unless you want to postulate new elements, and you claimed you weren't going to do that. What happens to helium atoms which are pushed together (by high pressure), or to a group of helium atoms with insufficient kinetic energy (temperature) to shake themselves apart? They stick to each other and form a liquid. Why do they do this? Van der Walls forces.

      This hypothetical mechanical apparatus which will hold atoms still and push them close to each other? It's replicating the still and close conditions under which helium is sticky enough to form a liquid. Since helium sticks to helium under those conditions, how is it going to be possible to engineer something that isn't sticky?

      I'm done.

      If you'd like to continue this pointless exchange, just imagine that in this post and alternating posts hereafter I point out that you've backpedaled yet again so that you're just describing chemisty as it's been practiced for decades, with all the work required to design specific reactants for each individual addition (but relabeled as 'nanotech' because that's the scientific flavor-of-the-month and grant money's being targetted there.)

      In the next and alternating posts thereafter imagine that I point out that the whatever aspects of this 'nanotech' process you claim aren't just chemistry with a new name won't work in the general case because you can't ignore the stickiness problem, and without generality of applicability this 'nanotech' has yet again cycled back to being just classic chemistry, requiring design of everything individually.

    37. Re:Well, I read the letters by Noren · · Score: 1
      It's this centuries version of the heavier-than-air flight debate, but with much, much greater implications.
      Either that or it's this centuries' artificial intelligence (or cold fusion, or faster-than-light travel...) debate. :-)
    38. Re:Well, I read the letters by MarkusQ · · Score: 1

      *sigh*

      We just aren't communicating here.

      Yes, even Helium atoms stick together under some conditions. Heck, anything with mass will stick together under some conditions, just due to gravity.

      But Smalley isn't claming that all atoms stick together under some conditions; he's claiming that the problem is "unavoidable" -- which, if cogent, must mean that there is no possible combination of atoms that can be formed into stable structures that won't stick together in such a way that it is not possible to work with them -- in short, that all such combinations of atoms will always stick together at that scale.

      Even if true, it doesn't mean you can't do sometrhing useful. Here's a sketch:

      1. Take two surfaces: on one, the part being constructed; on the other, some reactive "catalyst + new-bit-to-add" or "catalyst-that-cleaves-something-you-want-to-remov e"
      2. You bring them together, if necessary compensating for the changing forces as they aproach.
      3. They're stuck!
      4. Pull them apart. As you do so, you will have to overcome some attractive forces, but you can do so in all sorts of ways--after all, the forces of stickiness you are contending with are orders of magnitude smaller than bond stringths. If nothing else, use two horses and some rope.
      5. Lather, rinse, repeat.

      just imagine that in this post and alternating posts hereafter I point out that you've backpedaled yet again so that you're just describing chemisty as it's been practiced for decades, with all the work required to design specific reactants for each individual addition

      You just refuse to accept the point, don't you? No one is proposing magic new uber-chemistry, any more than new electronics was needed to make computers. But there comes a time when quatitative differences (especially in degree of control and overall complexity) warent a new way of looking at things, and that generally involves new terminology.

      Do you likewise object to the term "biology," since there's nothing that life forms do that can't be described by chemistry-as-it's-been-practiced-for-decades? (*smile* Although I suppose you might be a vitalist...) For that matter, botany and history are all just (admitedly very complex) chemistry too, right?

      with all the work required to design specific reactants for each individual addition...just classic chemistry, requiring design of everything individually.

      You're back to the design issue again? Computers have to be designed too. So do cars. And houses, and even clothing. But (in part because we give the designers a starting set of modular parts, and in part because we have standardized production tools and increasingly automated factories) it is still worthwhile to design and build things.

      Maybe it will help to think of it this way: nanotechnology aims to be to chemical/materials engineering roughly what the computer was to elecrical engineering.

      -- MarkusQ

  21. Scaring children - classic quote from Smalley by fruey · · Score: 5, Funny

    Leading up to my visit, the students were asked to write an essay on "Why I Am a Nanogeek." Hundreds responded, and I had the privilege of reading the top 30 essays, picking my favorite five. Of the essays I read, nearly half assumed that self-replicating nanobots were possible, and most were deeply worried about what would happen in their future as these nanobots spread around the world. [...] You and people around you have scared our children. (emphasis mine)

    So there, Smalley wins, he got scared children into the debate. Only thing likely to win debates better are beautiful women's tears, knockout punches, and defaulting by just leaving the room in a huff.

    --
    Conversion Rate Optimisation French / English consultant
    1. Re:Scaring children - classic quote from Smalley by Anonymous Coward · · Score: 0

      Think of the children!.... with crosshairs on their dopey little foreheads.

  22. Never say never by BillFarber · · Score: 3, Insightful

    No matter how unlikely it seems, I think you have to be very careful saying something is impossible. Especially something that we are only just starting to explore - such as nanotech.

    1. Re:Never say never by tftp · · Score: 1

      The reason is simple. If you say that X is possible, you only need to know one method how to do it. If you say that X is not possible, you must know all relevant methods in the Universe and show that none of them can do the job. The word "all", together with "the Universe", is a tough requirement to meet.

  23. Re:I never understood how it was supposed to work. by Anonymous Coward · · Score: 0

    No you don't, most people don't so don't feel bad. What's more bothering is the fact you're modded insightful...

  24. Possibilities... by dreamchaser · · Score: 1

    To paraphrase a saying that I cannot for the life of me find the author of (it was a Sci Fi author, please one of you MUST remember who said it): If a graybeard scientist says something is possible, pay attention to him. If that same graybeard scientist says something is impossible, he's wrong.

    1. Re:Possibilities... by palfrey · · Score: 1

      Arthur C. Clarke I believe

      --
      Beware the psychokinetic mimes!
    2. Re:Possibilities... by iawia · · Score: 1

      Funnily enough, Drexler mentions that same quotation in one of the letters:


      'A scientist whose research I respect has observed that "when a scientist says something is possible, they're probably underestimating how long it will take. But if they say it's impossible, they're probably wrong." The scientist quoted is, of course, Richard Smalley.'

    3. Re:Possibilities... by Noren · · Score: 2, Interesting
      [Arthur C.] Clarke's First Law(1962):
      When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.
      His Third Law is more well known, "Any sufficiently advanced technology is indistinguishable from magic."

      However, there's also Asimov's Corollary to Clarke's First Law (1977):

      When, however, the lay public rallies round an idea that is denounced by distinguished but elderly scientists and supports that idea with great fervor and emotion -- the distinguished but elderly scientists are then, after all, probably right.
    4. Re:Possibilities... by srn_test · · Score: 1

      I'm getting really tired of this quote.

      Lots of people have said lots of things are impossible, and most of them were right. It's selective memory - only the people who say things that are (in retrospect) wrong are remembered; the rest are forgotten. Who wants to remember that someone said that generating infinite power from a glass of water is impossible? Whereas remembering that someone talking waaay outside their field of knowledge said that travelling beyond the Earth's atmosphere was impossible is much more interesting.

    5. Re:Possibilities... by Anonymous Coward · · Score: 0

      Aeornautical engineers said it was impossible to go faster than the speed of sound.

      Actual rocket scientists thought it would be impossible for man to survive in space, that the radiation would fry him.

      The list goes on. Stop being such a pedantic asshat.

  25. Yesterday's crazy idea... by Unknown+Kadath · · Score: 1

    ...is tomorrow's rock-solid reality. Prominent scientists once thought supersonic flight was impossible, too, but tell that to Chuck Yeager. Hell, my job involves building a jet engine that has a cruising speed faster than Mach 1.

    Applied science is a big mountain, and we're still mucking about in the foothills.

    -Carolyn

    --
    Like Daddy always said: if you can't dazzle 'em with brilliance, baffle 'em with bullshit.
  26. molecular assembly + quantum computers... by karmaflux · · Score: 1

    This could be the start of something beautiful.

    Compare this with that.

    But this issue seems to be fraught with misunderstanding.

    --

    REM Old programmers don't die. They just GOSUB without RETURN.

  27. Don't hold it back. by Anonymous Coward · · Score: 0

    Please tell me how you really feel, don't hold it back.

  28. Re:I know this is offtopic, but... by Anonymous Coward · · Score: 0

    Your ideas are intriguing and I wish to subscribe to your newsletter. ...

  29. These discussions are almost irrelevant ... by dustpuppy · · Score: 3, Insightful
    since they discuss developments 'in the future'.

    As Dexter quotes Smalley:
    ... when a scientist says something is possible, they're probably underestimating how long it will take. But if they say it's impossible, they're probably wrong.

    Molecular assemblers are not currently possible so we're not discussing 'now'. As for the future, well anything is possible. Look back through history and I don't think anyone can seriously say that anything is impossible given a long enough timespan - given enough research and progress and time, humans will probably find ways to overcome any physical, chemical, biological etc limit.

    So if the future is certain, then all these discussions are about is when. Given the lack of developments in the nanotech area, i doubt anyone can give an accurate timeline as more research/developments is required.

    Therefore the whole discussion seems like a pissing contest since neither side can really provide any solid info to predict when their predications will become true.
    1. Re:These discussions are almost irrelevant ... by Anonymous Coward · · Score: 0

      Pigs still don't fly.

    2. Re:These discussions are almost irrelevant ... by Anonymous Coward · · Score: 0

      Will you be writing that check now, sir?

    3. Re:These discussions are almost irrelevant ... by Anonymous Coward · · Score: 0

      My genetically engineered five ass pig does.

    4. Re:These discussions are almost irrelevant ... by Valdrax · · Score: 1

      As for the future, well anything is possible.

      So what year do you think that we'll get perpetual motion machines, safe and survivable FTL travel, and the ability to perfectly predict both the position and the momentum of a single molecule?

      Some things are simply physically impossible because they violate the laws of physics, like perpetual motion machines. Others are economically unfeasable because they require too much energy or too many resources, like building a Dyson sphere. Molecular assemblers may be in one of these categories.

      --
      If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
    5. Re:These discussions are almost irrelevant ... by Anonymous Coward · · Score: 0

      Correction - things violate the *currently known* laws of physics. Important difference.

    6. Re:These discussions are almost irrelevant ... by Valdrax · · Score: 1

      Correction - things violate the *currently known* laws of physics. Important difference.

      Fundamentally, if laws of physics exist, some things must be by definition impossible. It is sheerest fallacy to say that, with time, anything is possible. Some things, by definition, have to be fundamentally impossible or utterly impractical. The examples I listed are what we currently understand to fall within those categories, and you are nitpicking examples with undisprovable statements rather than addressing the fundamental point that there are impossible goals.

      It is very likely that molecular assemblers may be one due to thermal and quantum effects.

      --
      If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
  30. If I had to bet by MarkusQ · · Score: 5, Insightful

    If I had to bet, I'd say that Drexler was right. Smalley seems to rely on strawman arguments (they'd be restricted to water) and arguments from incredulity (the fat fingers schtick). This is the same sort of plausible sounding arguments that have been used to "prove" (in my lifetime) that we will never detect planets around other stars, that we will never be able to image individual atoms, that I will never have a hi-res colour display on my desk, that we will never be able to clone a mammal, etc., etc.

    If you strip away the fancy words (and shamelessly simplify), this becomes much more obvious:

    Drexler: We can build structures with atoms exactly where we want them, within reasonable limits.

    Smalley:Your fingers are too big. Any robot you build will have fingers too big. It won't work.

    Drexler: We wouldn't use "fingers," we'd use molecules designed for the purpose.

    Smalley: I don't see how that could work.

    Drexler: Living cells do it all the time.

    Smalley: Ah, but they need water to do it. Your nano-things will only work in water.

    And so forth...

    Drexler may well be optimistic about the timeline, and may well be underestimating the difficulties, but I've yet to see an argument that it can't be done that holds up under critical examination.

    -- MarkusQ

    1. Re:If I had to bet by Simon+Hibbs · · Score: 3, Insightful

      >This is the same sort of plausible sounding arguments that have been used to "prove" (in my
      >lifetime) that we will never detect planets around other stars,.... etc....

      I see this argument all the time and it's totaly falacious. In my lifetime scientists have claimed that artificial inteligences will be so far superior to human inteligences that they will rule the world for us. When would this occur by? Well according to some 1960s AI pioneers, we'd be ruled by AIs by the 1980s.

      Meanwhile in 2003 we're still waiting for someone to even come up with a very rough architecture for building even a simplistic geenral purpose AI, let alone start the practical work of programming one. The same goes for nanotechnology. It's all handwaving, the nano pundits can't put forward any kind of actual theoretical design for a universal contsructor.

      Think of it this way. we're much better a building human scale robots, computers and machinery than nano scale ones. therefore a human scale or bigger universal constructor should be many orders of magnitudes easier to make than a nano scale one. Whn wa sthe last time you saw plans for a fully automated, compuetr controlled, humanless factory capable of creating any product, including a copy of itself?

      never, precisely. If we can't build one at all, or even come up with rough plans for one, what makes anyone think a nano scale version is any more practical?

      Simon Hibbs

    2. Re:If I had to bet by MarkusQ · · Score: 2, Informative

      You wrote:
      >This is the same sort of plausible sounding arguments that have been used to "prove" (in my

      >lifetime) that we will never detect planets around other stars,.... etc....

      I see this argument all the time and it's totaly falacious. In my lifetime scientists have claimed that artificial inteligences will be so far superior to human inteligences that they will rule the world for us. When would this occur by? Well according to some 1960s AI pioneers, we'd be ruled by AIs by the 1980s.

      Then you should read more carefully. What I said was that Smalley's arguments were invalid (specifically, that he raised strawmen and argued from incredulity, both of which are known types of faulty reasoning). I then listed a number of reasonably well known cases from the last few decades where this sort of reasoning had led to, what are in hindsight, wrong conclusions.

      I never claimed or implied that the existence of a flawed argument against a premise is a evidence for the premise.

      You imply that I hold this view, while I clearly state that I do not. I agree that the sort of argument that you describe is invalid, but that is not the sort of argument I made.

      -- MarkusQ

      P.S. If you are interested in an argument for Drexler's position that I find compelling, I can outline one:

      1. I accept the matterialist premise that there is nothing "magical" about life; anything that a living creature can do can at least in principle be done by a machine of some type.
      2. Living creatures build macroscopic objects out of complex components assembled to atomic precission.
      3. Therefore, we should at least in principle be able to do so too.
    3. Re:If I had to bet by ghutchis · · Score: 2, Insightful

      We can make macroscopic objects out of complex components already.

      But the problem is this--Drexler's theory is that we can make an arbitrary object. That's not necessarily true from biochemistry. There are a great diversity of molecules made by nature. But synthetic chemistry has been able to make molecules never made by nature.

      Does that mean we can use biochemical techniques to assemble macroscopic assemblies? No.

      The trick that life uses is called "self assembly." We haven't the least clue how proteins form 3D shapes from their constituents. It's a great unsolved problem in biology and chemistry. The first one to solve it wins at least ONE Nobel prize.

      From current research, we know that we cannot self-assemble every molecule we can imagine. Some will self-assemble and some different types of assemblies are possible. But we're still a *long* way from being able to assemble an abitrary combination--which Drexler requires.

      And if you resort to what life can do, we're quite limited. Has life ever made a skyscraper?

    4. Re:If I had to bet by Michael+Crutcher · · Score: 1
      Meanwhile in 2003 we're still waiting for someone to even come up with a very rough architecture for building even a simplistic geenral purpose AI, let alone start the practical work of programming one.

      It's my belief that this failure is largely a result of hardware and not software. Current analysis of the processing power of the human brain suggests that the raw computation power available to AI scientists have been pathetically inadequate. In the 80's researchers using PCs would have had the processing power of approximately a worm. There's only so much you can do with a small brain: tasks truly useful to humans (visual recognition, for example) are going to be impossible without similar processing abilities. There are good reasons that ants use chemical detection to identify other members of the colony instead of visualy recognizing them. This is starting to change.

      It's all handwaving, the nano pundits can't put forward any kind of actual theoretical design for a universal contsructor.

      Actually, several people have proposed designs for nano factories (and thus universal constructors). Incremental progress towards the components of these nanofactories is being made every day.

    5. Re:If I had to bet by jafuser · · Score: 1

      Even if the nano-things did only work in water, aren't we just talking about a construction event? Once the object we want is constructed, we can take it out of the "water" and use it.

      --
      Please consider making an automatic monthly recurring donation to the EFF
    6. Re:If I had to bet by nnnneedles · · Score: 1
      My bets are on Smalley.

      Smalley: The central problem I see with the nanobot self-assembler then is primarily chemistry. If the nanobot is restricted to be a water-based life-form, since this is the only way its molecular assembly tools will work, then there is a long list of vulnerabilities and limitations to what it can do. If it is a non-water-based life-form, then there is a vast area of chemistry that has eluded us for centuries.

      Please tell us about this new chemistry.

      Drexler: blah blah blah. I want money from the military. blah blah blah. Nanotechnology will be awesome.

      Smalley: I see you have now walked out of the room where I had led you to talk about real chemistry, and you are now back in your mechanical world.

      --
      Will code a sig generator for food
    7. Re:If I had to bet by NonSequor · · Score: 2, Informative

      There is no doubt that machines can be built that behave like cells. However, one should be careful not to claim without sufficient evidence that we can make cell-sized machines that do things that no cells can. Cells can't make exact copies of themselves and I don't believe a group of cells working together would have any more luck in completing that task.

      Smalley isn't arguing that nano-scale machines are impossible. He's arguing that, without breakthroughs in chemistry beyond what we can currently imagine (ie some manner of "enzymes" not dependent on water or some other liquid), any molecular assembler that depends on the exact placement of individual atoms will suffer from tremendous error rates rendering the likelihood of creating a functional product infinitesimal.

      I think Smalley went a bit far in declaring molecular assemblers impossible, but for now I don't think that we even know if the sorts of reaction paths needed exist or not.

      --
      My only political goal is to see to it that no political party achieves its goals.
    8. Re:If I had to bet by Anonymous Coward · · Score: 0

      It's most definitely not a straw man argument if it has the whole field of chemistry and biology behind it.

      You don't understand this exchange.

    9. Re:If I had to bet by drinkypoo · · Score: 2, Informative
      Hot damn, a whole army of straw men is marching through this post. "We can't make AIs, so we can't make nanomachines either!" I see this argument all the time, and it's totaly (sic)falacious (sic). And usually involves better spelling. Artificial inteligences (sic) haven't happened and we don't know why. As no robot we have yet built has the complexity of a human, we don't know if sufficiently complex devices automagically become self-aware. You have to understand that all your nervous tissue does some processing, and that we are still extremely unclear on just what goes on inside the brain, because we have no way to measure some of the effects which we now theorize occur in it.

      The only similarity between the problems of AI and Single-atom positioning in nanotechnology is that they are both problems which we have seen nature solve, which gives us hope that we too will one day solve them.

      Incidentally there is a lego mindstorms robot which can assemble copies of itself from parts lying on the table. If you can do that with a children's toy, then I have high hopes for purpose-built nanites doing the same thing.

      Your example of a self-replicating factory is simply another straw man because the problem of nanites building nanites is so different from the problem of factories building factories. Given the use of robotics in factories, you would have to have a chip fab, refineries, and so on. However if you accept that some whole parts may be thrown into the system (like packaged ICs) then it actually becomes relatively simple to build a self-replicating factory, just pointless.

      Nanites on the other hand are (will be) working with atoms. They don't need to do refining. The atoms they can manipulate are limited only by their manipulators, and if they have enough of each type of manipulator for each type of atom which is in their system, then they are physically capable of self-replication. Whether or not we will manage to make them do it is a question worth asking, but the most important question should be is it possible. Once we are sure things are possible we tend to wrap them up relatively rapidly thereafter.

      Nothing has been said yet to prove that self-replicating nanomachines are impossible. They're certainly unfeasible with today's technology, but the nice thing about technology is that it progresses as time goes by with the efforts of talented and driven individuals, in spite of the naysayers. Meanwhile, you have offered no new arguments against the idea, and in fact made no useful comparisons.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    10. Re:If I had to bet by MarkusQ · · Score: 3, Insightful

      1. We can make macroscopic objects out of complex components already.

        Strawman. The issue is complex components that have every atom where you want it (with perhaps some acceptance of a very low error rate).

      2. Drexler's theory is that we can make an arbitrary object.

        Strawman. The proposal is that we should be able to make arbitrary members of a huge class of useful objects, which isn't the same thing at all.

      3. Does that mean we can use biochemical techniques to assemble macroscopic assemblies? No.

        Strawman and argument from incredulity. First, this isn't Drexler's position, and second I see no reason why we couldn't, since trees do it on a regular basis.

      4. We haven't the least clue how proteins form 3D shapes from their constituents. It's a great unsolved problem in biology and chemistry. The first one to solve it wins at least ONE Nobel prize.

        Strawman. Ignoring the fact that we do know a great deal about how proteins fold, it doesn't matter since we don't need to understand the details anymore than the Wright brothers needed to understand how bird poop in order to build an airplane.

      5. From current research, we know that we cannot self-assemble every molecule we can imagine. Some will self-assemble and some different types of assemblies are possible. But we're still a *long* way from being able to assemble an abitrary combination--which Drexler requires.

        Argument from incredulity / ignorance (we don't know how to do it, therefore it can't be done) and Strawman.

      6. And if you resort to what life can do, we're quite limited. Has life ever made a skyscraper? Strawman.

        -- MarkusQ

    11. Re:If I had to bet by Simon+Hibbs · · Score: 1

      >The only similarity between the problems of AI and Single-atom positioning in nanotechnology is
      >that they are both problems which we have seen nature solve, which gives us hope that we too
      >will one day solve them.

      Well you're obviously aware of some discoveries I'm not. I'd love to see a reference for a natural process capable of constructing arbitrary assemplies of atoms. Nature's full of processes and structures that will produce only specific product structures or narrow classes of structures, but arbitrary possitioning of single atoms, regardless of the element or possition?

      This is the crux of the problem. Drexler is making handwaving claims that this will be doable, without actualy coming up with a concrete explanation of how it could be done.

      Absent even a theory of how to do something, claiming that it's doable is not exactly very scientific. Drexler writes specualtions about what may be possible, but offers only vague speculation about actualy doing it.

      Simon Hibbs

    12. Re:If I had to bet by MarkusQ · · Score: 2, Insightful

      Cells can't make exact copies of themselves and I don't believe a group of cells working together would have any more luck in completing that task.

      Exact? No. But functional? Sure. Cells do it all the time. In fact, birds do it. Bees do it. And from what I've been told, even educated fleas do it.

      He's arguing that, without breakthroughs in chemistry beyond what we can currently imagine (ie some manner of "enzymes" not dependent on water or some other liquid), any molecular assembler that depends on the exact placement of individual atoms will suffer from tremendous error rates rendering the likelihood of creating a functional product infinitesimal.

      Beyond what we can currently immagine? That's an argument from incredulity if I ever heard one. And a silly one, since we easily can imagine such things, and have examples (e.g. in gas phase) that come close to what is needed. As for the yields, the arguments get a little more complicated but it's really more a question of engineering than of basic science. There are all sorts of ways to deal with low yields, and armys of practitioners to apply them.

      I think Smalley went a bit far in declaring molecular assemblers impossible

      Yes. This is the essence of the disagreement. No one is saying we know how to build them now. But Smalley is (incorrectly, IMHO) jumping from this fact to the conculsion that there is no point in trying since the fact that we don't know how to build them now means that it is impossible to build them ever.

      -- MarkusQ

    13. Re:If I had to bet by MarkusQ · · Score: 2, Insightful

      Drexler is making handwaving claims that this will be doable, without actualy coming up with a concrete explanation of how it could be done.

      Hardly handwaving.

      If you have specific objections, raise them. But don't call something handwaving just because you haven't read it.

      -- MarkusQ

    14. Re:If I had to bet by MarkusQ · · Score: 1

      It's most definitely not a straw man argument if it has the whole field of chemistry and biology behind it.

      A "strawman" is an argument aimed at a misstatement of your opponent's possition. It doesn't matter who's "behind" it; at best, dragging in the issue makes it an argument by authority or ad hominim argument as well.

      -- MarkusQ

    15. Re:If I had to bet by Anonymous Coward · · Score: 0

      "....never, precisely. If we can't build one at all, or even come up with rough plans for one" Oh yes, we could, but it's just not practical, you'd need a foundry etc in that plant.. nano would be actually SIMPLER in that respect. And there *are* plans, evne on the net. you go searchig, you'll find em...

    16. Re:If I had to bet by Anonymous Coward · · Score: 0

      you're talkig nonsense. Hes not claiming that, hes not talking about unobtainium molecules, obviously you ever read anything he wrote. Again you show your igorance by saying Drexeler is talking by juggling induvidual atoms. He is not. Read before you post, and read carefully, for chrissake, people like you kill all meaningful discussions. btw look up " As discussed in (Drexler, 1992, chap. 8 & 9), mechanochemistry performed in a well-controlled environment appears sufficient to fabricate small devices from covalently bonded carbon (diamondoid). Merkle (1997d, 1998) describes additional reactions that could be used to build diamondoid products--a complete hydrocarbon "metabolism" capable of refreshing the molecular deposition tools, and Merkle and Freitas (2003) have analyzed a specific diamond mechanosynthesis tool in detail." or shut the fuck up, please. Thank you.

    17. Re:If I had to bet by Suicyco · · Score: 1

      Nasa did this already. Spent a lot of money designing a self replicating macro-scale factory.
      Cost 11.7 million to do the study. The aasm link below is an abstract of the findings.

      Links:

      http://www.rfreitas.com/Astro/GrowingLunarFactor y1 981.htm

      http://www.islandone.org/MMSG/aasm/

      http://www.rfreitas.com/Astro/ReproJBISJuly1980. ht m

    18. Re:If I had to bet by Razor+Blades+are+Not · · Score: 1

      Cells can't make exact copies of themselves and I don't believe a group of cells working together would have any more luck in completing that task.
      Exact? No. But functional? Sure. Cells do it all the time. In fact, birds do it. Bees do it. And from what I've been told, even educated fleas do it.


      Interesting. So biological reproduction falls under your definition of nano-technological reproduction ?
      I sort of thought that one of the goals of nanotechnology is to produce something that can get every atom exactly where you want it.
      Even with an acceptable low error rate (which you added to the mix in a previous post) cells don't do this. They do not create atomic-level reproductions of themselves, but rather a messy sort of "this protein goes here, and this one somewhere over there" sort of thing.
      Surely that sort of mechanism is more akin to biotechnology (and genetics) than nanotechnology.

    19. Re:If I had to bet by MarkusQ · · Score: 1

      I sort of thought that one of the goals of nanotechnology is to produce something that can get every atom exactly where you want it.

      A good working definition is the production of macroscopic quantities (and presumably useful assemblages) of complex components which are manufactured with every atom exactly where you want it.

      The point is that you make sure you have your components built exactly the way you want them (so they do what you want) but you don't waste effort over specifying, trying to put every component "where you want it" to the same accuracy unless it serves some purpose. In fact, it would be bad design (IMHO) to try to do so, since this would lead to the sort of brittleness Smalley is so adamant about.

      If we could accurately construct arbitrary "rational" diamondoid latice structures even 1/10 the scale of a typical cell we would have nanotech. (By rational I mean something along the lines of "excluding anything that is too unstable, or that can only be constructed by passing through one or more intermideate structures that are too unstable")

      In other words, cells do nanotech, but they don't make nearly as many interesting things as I expect we will be able to.

      Surely that sort of mechanism is more akin to biotechnology (and genetics) than nanotechnology.

      No, biotech et al presuppose a mechanism. Nanotech is something different, in the same way that aviation is a field apart from ornithology.

      -- MarkusQ

    20. Re:If I had to bet by RedWizzard · · Score: 1
      In my lifetime scientists have claimed that artificial inteligences will be so far superior to human inteligences that they will rule the world for us. When would this occur by? Well according to some 1960s AI pioneers, we'd be ruled by AIs by the 1980s.
      Got any references for this? When I studied AI (quite a few years ago) I don't remember seeing any claim remotely like this from AI researchers. Plenty of that sort of thing from SF authors, but nothing from AI researchers.
    21. Re:If I had to bet by Razor+Blades+are+Not · · Score: 1

      It's a blurry line, but if I understand you correctly, you're saying you could (in the cell example) use nanotechnology to make the proteins themselves, but don't care where they float around in the cell itself, so long as they're in the general area. Like the mitochondria, the cell wall, etc etc.

      So in other words, genetics and biotechnology just use the pre-existing nanotechnological mechanism that the cells provide to accomplish their goals?

      However, in the future, we may be able to provide a more powerful nano-mechanism with which we can accomplish other (even dissimilar) goals.

      Sounds fair enough to me.

    22. Re:If I had to bet by MarkusQ · · Score: 2, Informative

      It's a blurry line, but if I understand you correctly, you're saying you could (in the cell example) use nanotechnology to make the proteins themselves, but don't care where they float around in the cell itself, so long as they're in the general area. Like the mitochondria, the cell wall, etc etc.

      Pretty much. The only exception is that if we needed to we could position the parts more exactly. Cells do this, by the way. They allow stuff to float at random only to the extent that exact positioning doesn't matter. Otherwise, molecules (or even medium large structures) are towed into position by active mechanisms, including ratchet-and-prawl devices that walk along micro-tubules.

      -- MarkusQ

    23. Re:If I had to bet by regen · · Score: 1
      Think of it this way. we're much better a building human scale robots, computers and machinery than nano scale ones. therefore a human scale or bigger universal constructor should be many orders of magnitudes easier to make than a nano scale one. Whn wa sthe last time you saw plans for a fully automated, compuetr controlled, humanless factory capable of creating any product, including a copy of itself?

      Sixteen years ago, I worked on a Navy project called CCAPS (Circuit Card Assembly and Processing System). This system was capable of automattically building any circuit cards in use by the military. It could be boxed up to fit into 4 full size semi-trailers and could be relocated and set up to start production on short notice. The system cost something around 100 million dollars to design and construct the prototype. Even sixteen years ago, we could have built a large scale self replicating automatted factory, it probably would have cost around 10 billion, but it was technically possible. We just need the political will and the money to do this.

  31. Re:I never understood how it was supposed to work. by NichG · · Score: 4, Insightful

    Your body does what you've described all the time using DNA as the storage device, and only a two-part complex to do the actual assembly (ribosomes). One problem is, there we're talking about assembling from a fairly well defined set of components which are themselves complex enough to have ways of being selective (an amino acid of a particular geometry will bind preferably to a particular other structure). When you're talking about single atoms, there isn't that much of a geometric factor acting in your benefit anymore. Of course, we even manage that somewhat, since there are particular proteins in our body which end up having a single metal ion of some type or other in the center of them (hemoglobin - iron, chlorophyll - magnesium). The question is, can we generalize this and make it externally controllable (i.e. we feed the DNA-equivalent in by some remote process that preferably doesn't involve changing the environment we're building in).

    In the body, communication is usually done diffusing some chemical species that the other cells react to. So perhaps there'd be a byproduct of what one robot is building, and the others would be designed to be able to detect that byproduct to measure the local status. You should be able to build fairly complex uniform structures just knowing the local environment (periodic structures like crystals or networks), but it'd be difficult to build a single highly specified structure unless you used some other control mechanism with good spatial resolution, like in chip manufacture.

  32. And then I won't be allowed to teleport my Ferrari by Angostura · · Score: 0

    Damn!

  33. Yes they are possible by Ignorant+Aardvark · · Score: 4, Insightful

    Yes, they are possible. Look at what living cells already do ... every single one of them. They convert raw materials into cell structures. We already know it's possible; we just need to figure it out how to do it our way, or copy the way the cells do it.

    1. Re:Yes they are possible by Anonymous Coward · · Score: 0

      Strangely enough, we CAN copy the way cells do it. Have you ever heard of a DNA sequencing machine? We can make any sequence of DNA we want. That doesn't necessarily lead to molecular assembly.

    2. Re:Yes they are possible by zero+time+ghost · · Score: 1

      More important than "Can it be done?" is the question, "Will it be any different from what nature already does?"

      Nature may be a blind watchmaker, but she's had 4 billion years to evolve near-optimal solutions to the problems of assembling matter at the nano scale. I'd like to see nanotechnology provide new, optimal solutions, but I won't hold my breath. For now, my bet is that nanotechnology will wake up one day and realize that it is a subset of bioengineering.

    3. Re:Yes they are possible by drinkypoo · · Score: 1

      Nature may have invented the rotary engine but we made it put out 300hp and up. Nature may have invented the chemical reaction, but we used it to go to the moon - I should say, to a specific site on the moon. From what nature does accidentally, randomly, we can learn to do things specifically.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    4. Re:Yes they are possible by praedor · · Score: 1

      ...we just need to figure it out how to do it our way, or copy the way the cells do it.


      Sheesh. There already IS a way to duplicate them and the way they do it. It's called "sex". It's fun and can be nicely habit-forming.


      The smallest living, self-replicating cell IS the smallest possible "self-assembler". To be a "universal assembler" requires access to near infinite information/instructions and this means that there cannot be a universal assembler. Can't be done. The best you can do has already been done inside the smallest cells in existence. This would be somewhat larger than a pox virus (smallpox, monkeypox, cowpox, take your pick). Pox viruses are some of the largest viruses there are, retaining many functions full-blown cells but not quite retaining enough to be self-sufficient. They STILL need a larger cell to infect, this larger cell being big enough to contain the remaining information required just for self-replication.


      With bacteria, the more information you provide them for generating desired molecules (say some non-native, to that bacteria, protein), the higher the cost to that bacteria. There IS a size requirement for information. It isn't arbitrarily small. It cannot be arbitrarily condensed. It has size, mass, energetic cost. To deal with this takes more energy, size, mass.


      Basically, what Drexler wants? You cannot get there from here.

      --
      In Bushworld, they struggle to keep church and state separate in Iraq as they increasingly merge the two in America.
    5. Re:Yes they are possible by DrVomact · · Score: 0

      I don't think we're going to get very far arguing about whether nanotech is possible or not. In the most trivial sense, sure anything's possible if it's not logically impossible.

      Perhaps the question we ought to ask is whether machinelike nanotech such as Drexler envisions is likely. Is this tech a good bet--is it something we should invest money in? Personally, I wouldn't buy any stock in Drexler Inc. until he builds (or publishes plans for) a prototype that convincingly demonstrates that such nanomachines are not only possible, but practical. So how far beyond mere arm-waving has Drexler gotten? What has he done except publish academic papers that enthusiastically describe something that would be really neat, if it turns out to be practical? For that matter, suppose someone gave him a bunch of money. Exactly what would he do with it? What would be his research program, what specific engineering problems would he work to solve? I haven't heard anything of this sort from Drexler...but then I haven't been following his papers. If someone would like to enlighten me, I would be grateful.

      --
      Great men are almost always bad men--Lord Acton's Corollary
    6. Re:Yes they are possible by Anonymous Coward · · Score: 0

      Actually, the past 4 billion years have nothing to do with the evolution of cells but with the the evolution of species that are made up of cells. The cells themselves have always been identical in complexity to what we find today. Note that complexity here does not refer to specialization of cells but the universal ability of cells to build nano scale machines according to the specifications stored in the DNA molecule.

      In other words, the nano scale assembly found in cells is a prexisting condition for the evolution of life and had to be in place before evolution (as commonly defined) could take place at all.

      Please don't ask me how cells got to their present state of [unbelievable] complexity. If you discover that, you probably have discovered God ;-)

  34. for future reference by Anonymous Coward · · Score: 0

    why not include some footnotes? this is the internet, after all. links to supporting evidence would make this seem less trolly and much more authoritative.

    you really must love america quite a bit. it shows in your writing.

    1. Re:for future reference by Anonymous Coward · · Score: 0

      Here are your links regarding the post of historical retort:

      Morgenthau Plan

      Treaty of Brest-Litovsk

      Treaty of Versailles

      Napoleon poisoned

      Battle for Saipan-Japanese were no pushovers

      Presidential Election of 1876

      British burn Washington D.C. in 1814"

      George Washington hammers the Brits

      Also, please note that British propaganda against Napoleon was at least as strident as the American propaganda against Saddam Hussein.

  35. Cells do it by rlp · · Score: 2, Interesting

    Ribosomes are essentially molecular assemblers that build proteins out of amino acids using instructions from messenger RNA (originally transcribed from the DNA in the nucleus). So, it's not only possible, your cells are doing it as you read this.

    --
    [Insert pithy quote here]
  36. Re:Stop slashdotting nanotech sites by Anonymous Coward · · Score: 0

    yea, your comment resembles that of the comments about first powered flight experiments...

  37. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  38. I'm pretty sure they ARE possible by Blenderkitty · · Score: 1

    After all, what is the human body, but a set of carefully-constructed chemicals?
    What is a protein? Not a random conglomeration of molecules, but the last step in a long chain of directed chemical synthesis.

    I think the naysayers are being too close-minded in their consideration of what a molecular assembler may look like.

  39. Molecular Assemblers are OK, but by big-giant-head · · Score: 1

    Please no Molecular Cobol or Fortan compilers......

    --

    So Long and Thanks for all the Fish.
  40. It must be possible... by twoslice · · Score: 1
    K. Eric Drexler, Ph.D., cofounder of the Foresight Institute in Palo Alto, Calif.

    A Ph.D. who is a co-founder of Foresight.... can't be wrong...

    --

    From excellent karma to terible karma with a single +5 funny post...
  41. 3, 3, 3 replies in 1 by aminorex · · Score: 0

    [ Reply 1, Lusty and irrelevant ]

    An organic psychology at that. Or perhaps you
    meant psychology major. As you prefer.
    Personally, I'd rather a majorette.

    [ Reply 2, Recognizes absurd premise, but
    utterly fails to provide substantive
    refutation ]

    Oh yes, psychologists are renowned for their
    morality and maturity. Heh.

    [ Reply 3, Identifies ideological bias and
    rank absurdities, thus cogently defends
    subculture ]

    Making money is what keeps you from starving
    to death, since your hunter-gatherer skills
    have been displaced by reading and typing.
    Nanotech is cool because it offers the
    potential to eliminate hunger and disease.

    "... Warnings issued by ... Michael Crichton"
    is a quick grin. Should I fear cars and hotels
    because of Stephen King?

    --
    -I like my women like I like my tea: green-
    1. Re:3, 3, 3 replies in 1 by plinius · · Score: 1

      You are female, yes?
      Oh wait, you ended a sentence with "heh".
      That indicates a male.

    2. Re:3, 3, 3 replies in 1 by Eiki · · Score: 1

      A true scholar of /., that one is!

  42. Clarke's first law by alanxyzzy · · Score: 1, Insightful

    If an elderly but distinguished scientist says that something is possible he is almost certainly right,
    but if he says that it is impossible he is very probably wrong.'
    Arthur C. Clarke

  43. I'd love to read this article... by Masque · · Score: 2

    ...but I'm really not skilled in reading molecular assembly language.

  44. Re:I never understood how it was supposed to work. by clasher · · Score: 3, Informative
    Communication and memory may not be as large a requirement as one would think. Like complex action that insects (e.g. ants and termites) are able to perform it may be a case of Self Organization (haven't read this FAQ yet but it looks close to what I want to get across.)

    For a good book check out The Computational Beauty of Nature). Some tasks can be broken down into very simple repeated actions which simple machines can perform. The beauty of these system is that they require little communication between agents. Merely an awareness of what is around you and a simple list of tasks can create some complecated forms.

  45. Atom Level Manipulation by zhiwenchong · · Score: 2, Informative

    Take a look at this:
    Here

    From the article:
    "an atomic manipulation facility, unique in the world. This atomic manipulation facility will enable a new generation of experiments to unfold. It will allow McGill researchers to construct new devices atom by atom, thus developing the science and technology required for future electronic and biochemical systems."

    1. Re:Atom Level Manipulation by ghutchis · · Score: 1

      Oh sure, we can make things atom by atom.

      The problem is that the facility you mention (and the particular equipment you mention) is not a nano-assembler in Drexler's sense. It is not *itself* nano-scale.

      See, if you use an AFM or something macroscale to make things atom-by-atom, you're largely limited to making things one at a time.

      If you have a nanoscale assembler, you could have 10^23 of them and then you can make something in a reasonable amount of time (e.g. microsecons) and make a reasonable number too (e.g. millions).

      *That* is the key problem.

  46. Re:Is Smalley compensating for something? by Anonymous Coward · · Score: 0

    The guy who pulled my wisdom teeth was named "Dr. Mangle". True story.

  47. Re:I never understood how it was supposed to work. by Smiling_Jack · · Score: 2, Interesting

    Now, I have only a vague understanding of the subject, but from what I read, I was lead to believe that you didn't have one little agent running around like a little gnome (or group thereof) building some complicated structure. You had a sequence of these things which acted like an assembly line. Each agent knows how to slap a specific atom or subset of atoms onto some atomic structure it receives, and only does something when it receives that atomic structure. So there wouldn't really need to be any memory, or very little, since it only does a specific task repeatedly. The thing could almost be stateless.

    Again, this is my dim recollection from something I read awhile back, so I bow down before more informed heads.

  48. 'this time' is now... by djupedal · · Score: 1

    In my area, many of the car break-in's are targeting vehicle registrations and proofs-of-insurance...the cars themselves are generally of lesser value.

    When you can copy a car as easily as a document, the car master (think DVD) will become the target, and that will be the time when copies of vehicles become something to liscense, unless of course, you build your own, like many of us already do today.

    1. Re:'this time' is now... by wideBlueSkies · · Score: 1

      >>In my area, many of the car break-in's are targeting vehicle registrations and proofs-of-insurance...the cars themselves are generally of lesser value.

      Well then people should stop keeping them in the car eh? You should do this anyway, because if the car is stolen from the mall parking lot, you don't want Joe Car Thief to know where you live. Right?

      --
      Huh?
    2. Re:'this time' is now... by djupedal · · Score: 1

      Nice idea, until the cops want to see them and you've left them in the back pocket of your jeans that are going round and round in the washer.

    3. Re:'this time' is now... by wideBlueSkies · · Score: 1

      In my jurisdiction (new york city) you will get tickets for not having the insurance and registration cards.

      However if you mail the tickets back with photocopies of said documents, there's no penalty.

      What are the chances of being pulled over anyway? Better to deal with the municipality for not having the documents, than dealing with the trouble of having them stolen.

      wbs.

      --
      Huh?
    4. Re:'this time' is now... by djupedal · · Score: 1

      What about those states that tow/impound the vehicle if you're not carrying proof of insurance? No proof....off the road and call a friend.

    5. Re:'this time' is now... by wideBlueSkies · · Score: 1

      It's not like I'm saying that my solution is right for everyone.

      If it's so much trouble, then just leave the documents in the car. Whatever.....

      For my paranoid self, I'd still not leave the docs in the car. I'd (and do) make sure that I always have em' with me. Kind of like how I need my keys to drive the car. Keep them together (keys and docs).

      wbs.

      --
      Huh?
  49. See? by TheOoftheP · · Score: 0

    Who says open source developers are the only group that have flame wars instead of working?

  50. The real question by hexatron · · Score: 1

    The real question is: Where should research effort be put?
    Drexler has been pushing his simple-to-understand vision for some decades. Even a congressman can understand "We stick the atoms together to make the molecules by pushing them into place, just like we make tinkertoy stuff." It's a nice idea. But there is no known way to do it. And real chemists know that atoms are way too small and way too sticky and way too jumpy to be dealt with like bricks. It may not be impossible. But it is impossible right now, and bellowing about how nice it would be is just--bellowing.

    Meanwhile, plain old chemical reactions have kept you alive all your life. Your parents too. They do lots of impressive things--like make beer. Have one.

  51. Not really. by Thag · · Score: 1

    DNA acts as a template mechanism, which lets you build certain types of molecules using a specific set of operations.

    The whole point of nanotech is that it doesn't work like that: you can supposedly add one atom at a time anywhere on a molecule, or pluck an atom out of the middle of something. Which makes the problems much more difficult.

    Drexler should get credit for being a populizer of the concept of nanotech, but it's good to see an expert in the field giving him some peer review.

    Jon Acheson

    --
    All opinions expressed herein are my own, and not those of my employers, who are appalled.
  52. To Dr. Smalley by little1973 · · Score: 1

    I have learned to use the word 'impossible' with the greatest caution.

    -- Wernher Magnus Maximilian von Braun (1912-77)

    --
    Government cannot make man richer, but it can make him poorer. - Ludwig von Mises
    1. Re:To Dr. Smalley by Anonymous Coward · · Score: 0

      Personally, I've learned to use it more freely after reading free energy and other crackpot "science" sites.

  53. A Small Observations by Effugas · · Score: 1

    First, you can't use Smalley fingers, because they're too sticky: Whatever you're manipulating will attach to the finger due to proximity effects.

    Then, you can't use positional assembly, because objects don't stick to eachother just because they get close to one another.

    So, uh, which is it? Do or do not compatible molecules bind or adhere when brought in close proximity?

    I'm not a chemical engineer (obviously), but even I picked up on this interesting contradiction.

    --Dan

    1. Re:A Small Observations by bradbury · · Score: 1
      This depends upon what molecules are attached to the tip of the fingers and how they are attached. If they atoms/molecules are attached to the tip by ionic or hydrogen bonding then sending a small number of electrons down the tip should be sufficient to repel the atom/molecule at the proper time. There is also very complex atomic bonding theory where atoms/molecules have greater affinity for binding to other more preferable molecules rather than the molecules they may currently be bound to (stronger vs. weaker bonds). So one may transfer atomic groups bound to a tip to other surfaces under the right conditions.

      Obviously the positional assembly argument is ca-ca. Lets see -- you take a bunch of carbon atoms, bond them into some type of graphite sheet and then random motion causes them to curl up into a ball or a tube (where the free ends are in reasonable proximity) and voila you end up with a completely bonded buckyball or buckytube. The work for which Smalley won a Nobel prize would not have been possible if atoms in proper positions with respect to one another did not form bonds!

      Atoms in the proper state which are positioned properly with respect to each other will form bonds. Its the entire basis behind chemistry.

  54. Re:LITTLE GAY AMERICUNTS! by Anonymous Coward · · Score: 0

    Off-topic response to flamebait. This bears a strong smell of British authorship, so I shall tailor my retorts on this basis. First point, the British had about five years to put down the American Revolution before the French came in. At the time, King George III had an impressive Empire that was getting even bigger. The Americans had almost no industry and was under a near-total blockade during those five years. Milita troops achieved impressive victories or yielded Pyrrhic victories to the British in numerous battles such as Lexington, Bunker (Breed's) Hill, Brandywine, and King's Mountain. BTW, no Bourbon French soldiers were in those battles.

    The War of 1812 was a poor overall showing for the new nation. While the Brits were busy stoking up the Spanish ulcer, then joining the Allies in their eventual drive on Paris, they had an overseas force that beat a number of American armies and even burned the new national capital. For the Brits out there, jolly good show at Waterloo. Napoleon pressed you and the Prussians awfully hard before even the Young Guard broke and the whole French army was swept away. Welcome to the South Atlantic, your Highness! Oh, and then a British doctor slowly poisoned Napoleon with arsenic bringing on his untimely death. Pefidious Albion!

    Frankly, the Union Army of 1865 could have been loaded on the excellent Union Navy ships of 1865 and conquered most of Europe short of Prussia and Great Britain. Instead, it kept the screws on the former Confederacy until the backroom settlement of the disputed Presidential Election of 1876 (same Florida counties involved as year 2000!). Prussia took the liberty of conquering Austria, Denmark and France instead from 1864-1871. Blut und Ehre!

    In 1917, the Brits were nearing exhaustion and the French Army had gone into widespread mutiny following its mismanagement at Verdun and other debacles. The entry of the Americans injected new life into the Allied cause and helped turn back the redoubled German force that redeployed from the Eastern Front following the cowardly Treaty of Brest-Litovsk signed by the Russians. The Americans acquitted themselves very well on French battlefields using a great deal of French and British equipment. In 1947, as a full player in the postwar peace (unlike 1919), the Americans intelligently embraced the Marshall Plan of rebuilding Europe. In 1919 with the Treaty of Versailles, the French and British had embraced something much closer to the Morgenthau Plan of 1947. Henry Morgenthau, an American diplomat, wanted to turn Germany into a large, unarmed, non-industrialized, agrarian state.

    Also, regarding WW2, the Japanese were no pushover and the Europeans had little to do with their defeat. Mostly the Euros were disgraced by the Japanese as their Far Eastern colonies fell quickly before the expansion of the "Greater East Asia Co-Prosperity Sphere".

    To sum up, go read some history, moron!

  55. Transporting objct in particle streams. by the_2nd_coming · · Score: 1

    do, if you can assemble objects, could you disassemble them, and send their particles to another location and reassemble them there?

    if so, we have Star Trek Transporters.

    --



    I am the Alpha and the Omega-3
    1. Re:Transporting objct in particle streams. by Anonymous Coward · · Score: 0

      And replicators. Imagine disassembling last night's garbage into today's breakfast. Kinda gross but very cool. Landfills may look like raw material gold mines in the future.

    2. Re:Transporting objct in particle streams. by Saige · · Score: 1

      Not to go too off-topic here, but why do you need to send the particles? Why not just disassemble an object, and send the plans on how to reassemble the object to the destination point, where the object can be rebuilt? You could even reassemble the object with the materials in the place it was sent, since you already have the materials there.

      It would limit what you could assemble at the destination point to what materials you have on hand, though.

      And a philosophical question to go with it - if you disassemble a unique object, and rebuild it in point B with all new molecules, is it the same object? Or do the different molecules make it a "different" object, even though there is absolutely no identifiable difference?

      --
      "You know your god is man-made when he hates all the same people you do."
    3. Re:Transporting objct in particle streams. by the_2nd_coming · · Score: 1

      sorry, I would rather know that when I am disassembled, I will be reassembled with all the stuff I was made of originally.

      --



      I am the Alpha and the Omega-3
    4. Re:Transporting objct in particle streams. by Anonymous Coward · · Score: 0

      Arrrg, your toying our minds with the paradoxes and the counterintuition!

      What are the ethics of destroying the original 'you' once tranlocation has been verified?

      What if you dont? - and your double commits a crime?

      What if it became law that if you die your double must be destroyed?

      What if an unlicenced double of you went back in time....

      arrrg!

    5. Re:Transporting objct in particle streams. by Saige · · Score: 1

      Why? It's not like you're even made of the same stuff that you were a month ago. The molecules of your body are constantly changing - you literally are what you eat. So if you were made from different molecules, how is that any different from normal life - other than being done more quickly?

      --
      "You know your god is man-made when he hates all the same people you do."
  56. Keep your fararari. by fireboy1919 · · Score: 1

    They crash, get bad gas milage, cost a lot, and once you use it, you're stuck with a proprietary system that you can't upgrade. I'll be driving my open-source tank. They come up with upgrades for it every few months, they are free, and kernel version 2.6 is just about to come out...

    Wait, was I talking about cars or linux?

    --
    Mod me down and I will become more powerful than you can possibly imagine!
    1. Re:Keep your fararari. by Dr.+GeneMachine · · Score: 1

      Yeah, and sometimes you have to disassemble the motor and recompile it halfway between A and B...

      --
      This comment does not exist.
  57. Not Enough Information by Anonymous Coward · · Score: 0

    My chemistry background isn't tremendously deep, but I see Smalley's point. Right now we don't have a universal method for 'mating' arbitrary molecules with other ones on any particular axis we choose.

    What I'll have to figure out is if Smalley is really knocking over a straw horse. Is Drexler really saying that this could be done? That (and this is where my chemistry falls short), that you can create arbitrary valence bonds on whatever axis you choose between any two molecules/atoms whatever.

    If that is true, then 'yes', I have to concurr with Smalley that arbitrary matter compilation is a long, long way off.

    Contrarily, I was always under the assumption that the matter compilers would use a substance like carbon to build diamonoid substances and that the physical chemistry of this particular combination was doable.

    Maybe what needs to elucidated is (1) what elements and molecules Drexler proposes now (2) Why Smalley thinks this cannot be done even in specific cases.

    I think if diamondoid or other specific matter can be assembled, maybe that would be a springboard to enlighten us just how far it could be extended. As far as I can tell, the best we can do now is MEMS systems (Micro-Electro-Mechanical). What does MEMS tell us about even smaller scale structures? MEMs work. Just check out your latest DLP projectors.

  58. I prefer " Female, Japanese, Hot" by Anonymous Coward · · Score: 0



    I could delete my Yahoo personal ad.

  59. Drexler did WAY more for nanotech by Chemisor · · Score: 2, Insightful

    Although Feynman proposed the idea first, it was Drexler who actually developed practical ideas about how it could be done. It was Drexler who fully explored the implications of the new invention, benefits and dangers. It was Drexler who designed molecular machinery (in Nanosystems) and calculated their physical parameters.

  60. Christ by Anonymous Coward · · Score: 0

    Fark! Can we PLEASE STOP GATING ROLAND TO /.!

    I have Roland in my RSS reader. I have Slashdot in my RSS reader. Slashdot repeatedly tries to want to be a blog by grabbing thoughts from that community, but Slashdot doesn't need to be an aggregator for the weblog world!

    Please get an EDITORIAL CLUE!

  61. Debate Tactic Flaw by quantaq · · Score: 1

    Many of the arguments used on both sides involve generalizing by comparing to past examples: "Yes, but they said that such-and-such wouldn't be possible either." The success or failure of any previous, and unrelated in this case, venutre has no bearing whatsoever on whether or not the current one will succeed.

  62. Crichton, not Stephenson by stevesliva · · Score: 1
    Molecular assembler? Surely you mean Matter Compiler?
    Actually, the author and book you find mention of Molecular Assemblers in is the dreadfully awful Prey by the credulous luddite Michael Crichton.

    Michael Crichton a credulous luddite? No way, you say. Read the foreword to Prey and the book Travels. The guy's a whack-job.

    Prey was better the first times I read it: Sphere and The Andromeda Strain.

    --
    Who do you get to be an expert to tell you something's not obvious? The least insightful person you can find? -J Roberts
  63. Re:MOD THIS SHITCAKE DOWN by Anonymous Coward · · Score: 0

    Go Steve, go Steve!

  64. But what does it really refer to? by Chemisor · · Score: 1

    Do you think Smalley is a word to describe his inclinations or the size of his intellect?

  65. The Human Body, Man by Choco-man · · Score: 1

    Aren't biological systems essentially nano-constructs, comprised of very small 'builders' (enzymes) that do one thing and one thing only. Since there are so many builders that only do that one thing, memory all of a sudden doesn't become a huge requirement, rather the ability to turn them off/on at a given moment to direct the construction.

    Given this, it seems obvious that nanoconstruction at some level is possible. That doesn't necessarily mean we can throw a bunch of elements together and direct them to build a skyscraper, complete with office equipment and name plates on the doors. But it certainly does seem feasible to draw the analogy to biological systems that directed construction is possible.

  66. They try to come after you by jetmarc · · Score: 3, Interesting

    It doesn't need molecular technology. They already try to come after you even today. See this nice (and real) example:

    http://www.mb-portal.net/html/news/special/2003_ sl r-pl_us.htm

    Some guy from Poland "copied" the new Mercedes SLR, long before the real car hits the market. Mercedes tried to buy it from it to get it off the streets. Because that failed, they sue him.

    Marc

    1. Re:They try to come after you by iantri · · Score: 1
      Has this page had a visit to the Babel Fish by chance?

      It's completely Jabberwocky..

  67. May be possible, still will not happen! by John.P.Jones · · Score: 1
    The question of whether atomically constructing arbitrary large objects is possible is irrelevant.

    It won't ever happen because...

    1. It would be easier to construct 'The Matrix'.

    2. The construction of 'The Matrix' would remove the desire or need to do this.

    Many science fiction ideas can be disregarded in this way, including teleportation and time travel. Ignore the ludite anti-machine slant that 'The Matrix' movies have put on 'The Matrix' and you willl see the good it could be used for.

    Or perhaps it is like 'the one ring', none of us can wield it although we would use it to do good it would corrupt us.

  68. Matter compiler will contain assemblers. by Chemisor · · Score: 1

    A matter compiler, as described in "The Diamond Age" is simply a eutactic chamber containing a feed interface, which brings molecular building blocks into it, and some assemblers, which follow a specific program to build something out of those blocks. The MC is to assemblers is what a construction site is to bricklayers.

  69. Really understanding the debate by bradbury · · Score: 1
    This was a really interesting discussion, but in the end Smalley did not end up contributing much.

    There are more extensive technical discussions at nanodot.org here and here. One of the problems is that people, particularly Smalley who is a chemist cannot understand the merging of physics, biotech, nanotech, MEMS and computer science. Drexler and a few other scientists attempt to bring these all together. See particularly various comments on Nano@Home from Nov. 22-24 here.

    The point should be made that the problem does not appear to be with regard to molecular or atomic assembly. As others have pointed out the ribosome performs this task quite well. As do DNA polymerase, RNA polymerase and literally all of the enzymes known to biology (probably thousands). I have on my desk a basic Biochemistry textbook (Voet & Voet) documenting the 19-step conversion process of Lansterol into Cholesterol which tends to be performed atom by atom or small molecule by small molecule. And this doesn't include the extensive number of reactions that lead up to cholesterol synthesis from Acetyl-CoA! All of these are mediated by enzymes that add or remove atoms or small molecular groups.

    So the problem appears to be that Smalley objects to mechanosynthesis in a vacuum or an inert atmosphere (or even an atmosphere which will not interfere with the reactants). Yet he does not make any case for that. Even if his "fat fingers" argument was valid that would still not prevent one from creating nano-structured materials with somewhat less density. Buckyballs and carbon nanotubes are not exactly the most dense materials one can envision. He presents no strong argument with respect to the limits of what could not be constructed with "fat fingers".

    The discussion from my perspective is a disappointment.

  70. Drexelers book online by Rxke · · Score: 1

    Engines of creation, as mentioned in the article, is available online, and in palmreader format at http://www.foresight.org/EOC/

  71. Wesley, get in here! by rjelks · · Score: 1

    We can make them, but how do we get them out of the plasma conduits? __

  72. What about quantum states? by poszi · · Score: 1
    How can a deterministic molecular assempler allow for these?

    And quantum states? They cannot be copied due to no-cloning theorem. In many cases it won't matter but if you assemble a complex and dynamic system (e.g. a living organism), will it work when all the quantum states of the molecules are random?

    --

    Save the bandwidth. Don't use sigs!

    1. Re:What about quantum states? by ghutchis · · Score: 1

      Nobody knows. The assumption is that this is possible--after all, we're not always made of the same atoms. If I ingest some isotope-labeled food and I see that some of the nitrogen ends up in my brain, then a few weeks later it's gone. Our bodies recycle proteins, carbohydrates and fats on a continual basis. We have to be more than just the sum of our quantum states. But how can we be sure what's important and what's not? Do you want to run that experiment?

  73. That would be "emacs"? by Anonymous Coward · · Score: 0

    My favorite Matter Compiler!=))

  74. What about plagues? by Chemisor · · Score: 2, Informative

    Everyone seems to ignore the fact the with nanotechnology any disgruntled employee can manufacture a nanoplague that will kill off the whole world's population. Imagine something like a miniature time bomb that spreads like a cold virus. At a predetermined time it explodes (Diamond Age's cookie cutters), produces a poison, or compiles a toaster in your brain. With a GPS antenna (graphite is an pretty good conductor) this could be very location specific. With the capability to map the bloodstream, it could selectively kill fat people (body mass index), stupid people (small brains), blacks (thick lips), various asian races (epicanthic fold variances), ugly people (by scanning the face). And all this is no more difficult than compiling a toaster. You can't even enforce assembler containment; read about how Hackworth stole the primer (Diamond Age): any engineer working with assemblers could do exactly the same thing to get himself one. And this ONE MAN can kill off everyone in the world. Now tell me, which benefit of nanotech will offset this not-too-negligible danger?

    1. Re:What about plagues? by Anonymous Coward · · Score: 0

      How is this risk any different than the risk of mass ebola infection by bio-terrorists today? To me this would just be another weapon of mass destruction to worry about.

      Viruses are also self replicating, morphing organisms.

      You can't enforce virus containment.

      There is already so much risk from idiots, that one more, that we can't do anything about, won't make a difference.

    2. Re:What about plagues? by Anonymous Coward · · Score: 0

      Nobody would ever have to work a day in their lives for food.

    3. Re:What about plagues? by Saige · · Score: 1

      Well, you could have a disgruntled engineer construct a rogue nuclear weapon and use it to destroy a city. There are plenty of unaccounted for nuclear materials out there, and it's not like all the plans for nuclear weapons are in top secret military facilities. But yet nobody has done so yet.

      A case could be made that by the time a person gains the education to be able to construct such a device (nuclear weapon/rogue nanomachine), that the people with the means and the mental issues to cause such destruction/death will be weeded out.
      And if you read Drexler's book Engines of Creation, there are proposed systems that could be constructed to keep check of nanomachines. The key is to focus on developing the defensive systems as quickly as possible, to minimize the time period that nanomachines could exist unchecked in the wild.

      Pehaps the number one method of preventing such occurences is to try and find the way to minimize the number of people with such strong hatred of other people as to be willing to do that. We're not making any attempts to do so at the moment...

      --
      "You know your god is man-made when he hates all the same people you do."
    4. Re:What about plagues? by randombit · · Score: 1

      Everyone seems to ignore the fact the with nanotechnology any disgruntled employee can manufacture a nanoplague that will kill off the whole world's population. Imagine something like a miniature time bomb that spreads like a cold virus.

      See also: Herbert's "The White Plauge" (hardly his best book, but similiar to what you're talking about here).

  75. Piquepaille adds nothing except self promotion by Eldie · · Score: 1

    I've recently noticed that Roland Piquepaille has submitted a lot of stories to slashdot. What do they all have in common? They are self promotion pieces pointing the reader back at Roland's blog. What do you find there? A few paragraphs excerpted from the real story, and a link to the real story. What value does Roland add? _ZERO_.

    Why do the slashdot editors condone this blatant self promotion? I thought that was exclusively their province.

  76. Re:LITTLE GAY AMERICUNTS! by Anonymous Coward · · Score: 0

    You're wrong in your assumption that you're dealing with a Brit. I'm actually from another large European country which shall go unnamed here. Anyway, I didn't write the text myself. Was posted by a Frenchman on some stupid "patriotic" message board I troll on occasionally.

    I absolutely love it because no braindead American can resist to comment it.

  77. Finally a use for my Ph.D. on /.! by nallen · · Score: 1

    The problem with manipulating atoms is that they are "fuzzy", in the sense that we don't know exactly where they are. This is quatum mechanics coming in to play. Our current understanding must treat atoms statistically. This brings up serious theoretical issues with nanoassemblers.

    As a response to those you point out that "Biology does it all the time," they have a misunderstanding of the differences between nanofabrication and molecular catalysis. Cells build things by using molecular templates and selective enzymic catalysis, these are very chemical in nature. The idea of nano assemblers treats atoms as if they are bricks that can be stacked. Enzymes aren't magic, they are in the simplest sense templates that allow reactions that could already happen to occur faster.

    Don't fall in to the trap of simply relabeling technology with new buzz words, catalysis isn't nanotech.

    1. Re:Finally a use for my Ph.D. on /.! by Anonymous Coward · · Score: 0

      Thats the best summary of the problem i've read here so far.

      Sure the problem is that atoms 'won't play ball' (pun intended).

      First you have to know.

      1) Exactly what you have - whats its spacial status do I have an l- isomer? How do I know one of my atoms isn't an isotope?

      2) Its exact energy state - in what valency/energy state is every electron ?

      3) Its exact orientation in 3D space

      Knowing all this you then have to be able to

      1) rotate the piece

      2) translate the piece

      both on the sub-nanometer scale

      and lastly

      3) pray the exact quantum conditions of the target atom/molecule are just as you want them.

      Anyone hear of Heisenburg?

      Outside that you only have 'statistical' control - which is what macrochemistry has always been about.

    2. Re:Finally a use for my Ph.D. on /.! by iggymanz · · Score: 1

      I think anything needed & useful to us can be made by biological processes, no need for nano-assembly to make ANY kind of thing. We see in nature materials with many times the strength of steel, we see data memory & computing structures, power generation & storage, lighting, water purification, medicines etc.etc. So while we may not be building gold bricks out of seawater because we'd like to, we will get necessary things through advanced genetics & biology.

  78. New Godwin's Law? by Rinikusu · · Score: 1

    Hrm..

    It does seem that bringing "children" into the debate is occurring with quite a bit of frequency these days, with no thought to the applicability of such argument or relevance to the actual topic at hand..

    We already have the famed "Godwin's Law" regarding comparisons with Hitler, should we now coin a term for "Think of the Children" arguments? But whom to name it after...

    --
    If you were me, you'd be good lookin'. - six string samurai
    1. Re:New Godwin's Law? by Shajenko42 · · Score: 1

      Helen Lovejoy?

  79. through the mud... by Anonymous Coward · · Score: 0

    Sorry, couldn't resist this one:
    Can nanobots build a copy of my wife and deprogram the bitching thing?

  80. Re:LITTLE GAY AMERICUNTS! by Anonymous Coward · · Score: 0

    You read my post and still call ME braindead?! Oh, Puhlease. Way to go with your destructive, non-factual troll/flamebait. I guess it makes some people happier to go around destroying a reputation rather than building one. My advice is to try and be a fountain, not a drain. Or, for the more erudite, as Goethe said on his deathbed, "Mehr Licht!"

  81. Who is right? by Anonymous Coward · · Score: 0

    The first one to actually demostrate a working molecular assembler. This *is* science after all! Then only religious fanatics or the extremely stooopid can argue against it.

  82. Life is the model for nanotechnology by Anonymous Coward · · Score: 0

    As some comments get at, but don't explicitly state, the biochemical processes of living organisms already express many of the claimed aims of nanotechnology.

    I would even postulate that given the power of evolution acting on life to select the most powerful way to enable a function, that the only practical way to impliment nanotechnology is using life as a guide (biochemistry, enzymology, etc). Want microscopic motors? Look at how bacterial flagella are organized.

    Now let's take the next step: if we want nanotechnology, modify life forms to create it. So, if we want tiny subs reaming out our arteries, or repairing organs, modify viruses, bacteria, or parasites to do so. It's the only way!

  83. Re:I never understood how it was supposed to work. by RLW · · Score: 1

    What about the equivalent of an inkjet printer; instead you have a matterjet printer? Working at near absolute zero you eliminate the problems of temperature and atomic motion (although this creates the problem of making a design that can transition from really f-ing cold to room temp.) That cup of Earl Grey, Hot will start off as Earl Grey colder than anything and then add heat!

    Simple right? No? well flight was impossible for the majority of human history and so was medical treatment that actually helped instead of harmed. Oh, yeh and the earth was flat once. Communicating across the world was once impossible, then time/resource consuming, then incontinent, to nearly instantaneous and universal. Maybe the matterjet won't work but something will and it'll get better, cheaper, and universal. I hope I live to see it.

  84. Give that man a sammich by Anonymous Coward · · Score: 0

    Wish I had some mod points, that was an excellent rebuttal.

  85. Re:Is Smalley compensating for something? by Anonymous Coward · · Score: 0

    I believe you! Every story on Slashdot is completely true!

    Yours truly, the Iraqi Infomation Minister.

  86. Re:LITTLE GAY AMERICUNTS! by Anonymous Coward · · Score: 0

    Of course I read your post. I even read your reply to my reply. That's what trolling is about. Watching how people swallow the bait and laughing at them. In case you haven't noticed: I don't care about reputations and patriotism at all and am quite aware of the fact that my original posting contains some fiction.

    But you seem to be a nice guy, so don't take all this too serious and move on with your patriotic life now, okay?

  87. Existence proof. by AJWM · · Score: 2, Interesting

    Of course molecular assemblers are possible. Your body contains billions of them -- ribosomes.

    A ribosome (a combination of several large protein molecules) constructs arbitrary protein molecules from individual amino acids according to the instructions on a strand of RNA (copied from DNA). Sounds like a molecular assembler to me.

    Now, as to whether they can be made smaller and more flexible than that (nanotech's "universal assembler") is another question -- ribosomes may turn out to be the minimum possible assembler. Or not.

    --
    -- Alastair
  88. Ferraris and bombs... by internet-redstar · · Score: 1
    The license of originality for this Ferrari could possibly be issued in a one-time-readable quantum cryptography way.
    If one reads the license with the Replicator (TM), you would destroy the license (and the originality of your expensive machine). The only one who can create a new license of originality (using their secret key) are the Ferrari vehicle manufacturers...

    Flying the Ferrari through the Replicator will void your 'license to use' in that way. So I don't think it will be a problem for the company.

    To build a H-bomb, you need a lot of uranium and plutonium; as far as I know, you can only get to the point of H fission by creating enough energy with an embedded 'traditional' nuclear bomb inside (sort of).

    I presume that the uncracked version of the Replicator (TM) would not contain a filled jar of Uranium/Plutonium. The tgz-ed information to replicate a full-blown uranium mining facility would probably be available for download from the FastTrack network.

    But IANANanotechnologist, but a JAMSAR (Just A Mortal Slashdot Article Reader)

  89. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  90. Re:fp by Anonymous Coward · · Score: 0

    No, I didn't get the memo. But you can send it to me at SlashDotFP@mailinator.com

  91. ferrari copying by erwinkarim · · Score: 0

    wrong about being able to copy ferarri because they are not IP. the design of car is an IP.

    there used to be a lot of lamborghini and ferarri replica on ebay. there's one company who really made a good looking ferarri out of a chevy v6. they made it so good that ferrari sue the company. now other people make replicas w/ lambo and other hot-stuff cars. you copy it too good, the car company will sue your ass off.

    don't think they made ferarri replicas? take a look at ebaymotors.

  92. Warning: Goatse! by stup · · Score: 1

    Be warned, the link in the Anonymous parent comment is not to anything you'll forget soon. It's biology, but not at all nano. Uck!

  93. Re:MOD THIS SHITCAKE DOWN by Anonymous Coward · · Score: 0

    How is this flamebait? This is VERY insightful is you ask me!

  94. Scaling down to molecular assemblers by dpilot · · Score: 1

    On the serious side, before getting to the fantasy below...

    There is a fuzzy dividing line between the macro and microscopic worlds. Various experiments have been able to move that line, AFAIK always upwards, but the line is still there. At some point, materials quit acting classically and start acting quantumly. Molecular assemblers are clearly below that line.

    It's really hard to 'work your way down' to the molecular assembler level, because you're either classical or quantum. Even the experiments that elevate quantum effects into normally classical space are highly specific, and could not likely be extended to an assembler.

    The chicken-and-egg problem mentioned elsewhere has a solution. Some 'proto-chicken' laid the first 'true-chicken' egg that hatched and became the first chicken. Rather obvious with a little thought.

    The molecular assembler isn't so easy, and building the bridge is tough. I see two ways, either building really simple assemblers in bulk, in 'test tubes' somewhat as we build lipospheres, today, and using them to build more complex assemblers. Or building simple, gross molecular assemblers out of the smallest classical assemblers (STM on steriods?) we can make.

    In either case, it's a bootstrap process, and by the time we've bootstrapped we may find that we're not exactly where we expected to be. Not necessarily better or worse, just different. Pre-bootstrap expectations are likely to be wrong.

    A pet fantasy from my high school days (early 70's) was to build a smaller Waldo-style robot. (mimic my movements, at another place/scale) Use that Waldo to build a yet smaller one, and so on.

    The final goal of this progression was to go walking down the grooves of my favorite vinyl LPs, carrying a micro-trowel and a micro-bucket of vinyl patch, and fix the really annoying clicks and pops by hand.

    This was never a serious fantasy, but a fun thought. Not only did I not figure the needed size of the Waldo, beyond the 1-mil (25.4 uM) scale, I didn't figure the length of the virtual hike it would take for one LP.

    Not only were vinyl LPs obsolete before nanotech (It didn't have that name, then.) truly approached, my old 'temporary, until I can afford better' AR-XA turntable outlasted the format.

    --
    The living have better things to do than to continue hating the dead.
  95. Because it is undetectable and instantaneous. by Chemisor · · Score: 1

    > How is this risk any different than the risk of mass ebola infection by bio-terrorists today?

    With a biological infection you generally can quarantine the sick and thus contain the spread if you catch it early enough. This is because ebola and all other diseases start killing the host as soon as they can. A nanoplague can spread with no symptoms whatsoever, since it only needs to create a small spore synthesis plant inside the body, and can be triggered at a predetermined time, so that there is no way to "stop" its spread - everyone dies at exactly the same time. There is also no possible treatment, since the death is instantaneous. Biological diseases, including ebola, never have a 100% fatality rate because they usually can be treated, if not cured, like anthrax. Detectability is also a problem since, unlike biological infections, there would be no symptoms in carriers or those about to die. A nightmare, isn't it?

    1. Re:Because it is undetectable and instantaneous. by Patrik_AKA_RedX · · Score: 1

      How much differend would that be with AIDS? The virus that causes AIDS remains dormend for years after someone is infected. These people show no symptoms either.

  96. We already have that. by Chemisor · · Score: 1

    > Nobody would ever have to work a day in their lives for food.

    We already have this. It is called "welfare". People on welfare tend to stay at home, do nothing, and have lots of children (to raise benefits). Those children will inevitably grow up and also be on welfare. Thus the system perpetuates, but nobody says it is a good thing.

    1. Re:We already have that. by Patrik_AKA_RedX · · Score: 1

      Cool! free money, no work and plenty of sex!
      where do I sign up for this?

  97. Offtopic: entropy by Anonymous Coward · · Score: 0

    I wonder why, when talking about robots made of thousands of atoms, people never seem to mention how entropy and thermal migration type things will effect such a machine.

    While I don't think that we have reached the lower limits of scale by any strech, as a materials engineer it bothers me some that I've never seen this problem discussed. What happens when a stray gamma ray or something reprograms my little nanobot?

    And what of thermodynamic laws of matter? There are a lot of ways of arranging things that are inherently unstable. If you put matter into a shape that is highly energeticly unstable, the atoms will spontaneously hop to lower the energy of the system. Different materials next to each other wil spontaneously alloy (look up 'diffusion couple' of you aren't familiar with this) not to mention that for every second a bot is exposed to air, free sulfur and other junk is being deposited on the surface.

    If there is a decent discussion anywhere, please point me at it, or respond... Just one of those nagging issues I have with the idea...

  98. bricks and cells by dpilot · · Score: 1

    Convenient leading choice of metaphor, thanks.

    There are some who theorize (Sorry, no reference, I read this years (decades) ago in dead tree form.) that life began bootstrapped on clays.

    Some clays at the microscopic scale carry electrostatic charges, and at that level can be somewhat self-assembling through sedimentation. So there is a micro-structure there. Now take the water that that microstructured clay is immersed in (We are talking about sedimentation, after all.) and put some organic impurities in it. Those impurities will tend to self-align on the clay face, drive by diffusion, micro-scale surface topology, and electrostatic charge. At some point you may have a sufficiently advanced scum on the clay surface that if a chance current breaks it off, it can 'do something' on it's on - a sort of proto-life.

    This scenario is a case of a self-assembled unit that assembles something else.

    --
    The living have better things to do than to continue hating the dead.
  99. Out to Sea by ansible · · Score: 1

    It is not really clear to me why Smalley is so hung up on liquide-phase chemistry.

    No one is saying mechanosynthesis is going to be easy. There's going to be a lot, lot, lot of grunt work to figure out what reactions are possible, which are reliable, and which of those are actually useful.

    But there's an awful lot of cleverness out there, and I'm sure we'll be able to figure out enough useful building blocks. We may end up always using liquid-phase chemistry to build precursor molecules, but I'm convinced that mechanosynthesis will allow the construction of arbitrary molecules and objects.

  100. Re:I never understood how it was supposed to work. by Rxke · · Score: 1

    didn't want to bring you down, my english is bad, i liked your post becaus you say maybe i dont know, and are modded insightful. but /. moderation is so bad, sometimes, i return to read at -1, if very interesting article, sometimes (no, a lot of times!) good posts are -1, sometimes idiot posts +5 with very much answers to them, crazy.

  101. Re:Open Source to the Rescue by RobertAG · · Score: 1

    Nope!

    Instead, you and your friends will get together, decide that Ferrari's design is NOT optimal, create a better design, open source it and allow others to contribute to it.

    The end result will be that the proprietary design will be less desired than the open source one and Ferarri will go the way of the dinosaurs (the large ones, not the flying ones).

  102. I've read the letters by Scholasticus · · Score: 1

    I've read the letters of both Smalley and Drexler, and as far as I can tell they're talking past each other. Drexler thinks molecular assemblers are possible, but hasn't come up with a practical way to build them. Smalley thinks that molecular assemblers are impossible, and has come up with some reasons why he thinks so.

    I'm tempted to side with Drexler, but really there is no concrete evidence that either one is right. Both are proposing hypotheses now, and I see two possible outcomes: 1)Drexler will be proved right because someone will succeed in building molecular assemblers, or 2) After centuries of attempts at building molecular assemblers, engineers and scientists will give up, more or less admitting that Smalley was right.

    At present, I don't think the question can really be settled by argumentation.

    Of course, there is a third possibility: nobody will ever try to build a molecular assembler (though I think this is unlikely).

  103. Re: Existence proof by abb3w · · Score: 2, Insightful

    In your terms Smalley's objection is that the current existance proof is a special case. Specifically, Smalley points out that the extant examples are all dependent on WATER BASED CHEMISTRY. Water is one of the most powerfully corrosive solvents known. Smalley implies this rules out nanoassembly of items unstable in water... such as steel, silicon, titanium, &c. At the very least, it presents a highly non-trivial problem, and Smalley thus challenges Drexler to provide an non-handwaving solution. Drexler ducks; there may be a solution (or solvent), but it ain't simple.

    The biotic existance proof proves it's not impossible, but doesn't prove that general materials assemblers are possible, due to the limitations of water chemistry. (I don't count humans as a general nanoassembler; not cost effective.)

    --
    //Information does not want to be free; it wants to breed.
  104. It really is quite simple... by praedor · · Score: 2, Insightful

    The smallest self-assembler is equivalent in size to the smallest microorganism. Nanotech devices cannot do better than the already extant nanotech devices: all the enzymes and proteins in a cell (any cell, any virus, any bacterium). Not a single enzyme or protein in any cell anywhere is capable of reproducing itself from first principles (atoms). Even the small "self-replicating" prion protein cannot make itself from scratch. It requires a premade template protein assembled by ribosomes using instructions provided by RNA which was produced by RNA polymerase, which is itself a copy of a DNA "library" generated by an evolutionary decendent of RNA polymerase called DNA polymerase.


    The closest thing to a self-assembling "machine" would be the hypothetical self-replicating RNA molecule of primordial, pre-life earth. The presumed precursor to all things living today. But you don't get much use from a self-replicating RNA except more copies of that RNA, which doesn't even do anything but copy itself. It cannot be a universal replicator. Nothing can. Information takes space. All the information needed to replicate the smallest possible item, a prion, is exactly the size of a prion - and it doesn't do anything de novo, just refolds an already extant protein generated by the minimum-sized machinery necessary to generate that protein. Thus a virus could be considered a measure of the smallest possible self replicant capable of producing complex systems (the virus).


    But wait! A virus CANNOT be the smallest possible self-replicator. It REQUIRES a pre-existent cell with all the machinery necessary to start from first principles (atoms and small molecules) and generate more complex "machines" and structures. Thus a virus is not, and can not be considered self-contained anymore than a prion can. No, a full-blown cell, the smallest being independently replicable bacteria, are the smallest possible self-replicator starting from first principles (atoms and molecules as a source of building material). Drexler, not being really versed in anything beyond simple chemistry and physics sees things through rose-colored glasses, and ignores the facts around him.


    If a self-replicating, autonomous nano universal replicator were actually possible, it would have won evolutionarily as the most efficient replicator and it would be the dominant form of replicator on earth. Hmmm...nope, none around here. There isn't even anything CLOSE to such a beastie within ANY living organism of ANY type.

    --
    In Bushworld, they struggle to keep church and state separate in Iraq as they increasingly merge the two in America.
    1. Re:It really is quite simple... by Anonymous Coward · · Score: 0

      Ok, you make a definition of a minimal self replicating entity, and a context or environment for this entity - those being exemplified by current biology and the 'cell'.

      I agree that viewed in this context there are obvious theoretical and experimentally verified limitations on what can happen. That science of classical chemistry, or through the eyes I as a geek of computing/math see it - geometry, gives us exactly what you say:

      Rules which determine what is buildable from what.

      The pro nanos seem to be saying its possible to step ouside of these rules and create arbitary matter. I'm not sure what the ultimate relevance of self replication is - or if thats the important point.

      What is the point is that some would hold it is IMPOSSIBLE to step out of the rules while some would assert that engineering on the quantum level will allow us to rewrite the rules of molecular combinatorics.

    2. Re:It really is quite simple... by SB9876 · · Score: 1

      While your general points are good, there's some flaws in your reasoning.
      I agree that there is a bottom limit to the size of an autonomously replicating unit. However, using a bacterium as the bottom size limit is not an airtight case. Contrary to popular belief, evolution does not find the globally optimal solution to a problem. Rather, evolution often finds itself bound by the history of previous changes and is locked into suboptimal solutions.
      For example, if our genetic code had more bases, our genome could be stored in a much smaller volume and be replicated with much less energy required. However, evolution happened to pick 4 bases and now we're stuck with it. (although some researchers at the Scrips institutes, I think, are working on adding some new bases for bioengineering purposes)
      Furthermore, biology is largely limited to 20 amino acids for its building blocks. If the fundamental building blocks of proteins were more chemically diverse or allowed things like branched proteins, it is quite likely that most enzymes would be radically smaller. The functions of most enzymes are contained in a tiny fraction (a few %) of the total residues, the rest is largely filler that results from having a randonly generated linear polymer act as the backbone.

      If we could rationally design life, the minimal size for a self-relicating organism would be drastically reduced. What's the size of this organism? I don't know. AFAIK, noone's ever worked out the mathematics for self-replication. Obviously, there is some mathematical value of complexity which represents the absolute minimum requirement for a self-replicating organism in a non-hostile environment (obviously the complexity differs from a construct that replicates in a lab vs one that replicates in the 'wild') which corresonds to some spercific atomic structure.

      BUT, you say, what about an arbitrary assembler? This too is probably possible - I point towards human society in general. It can be treated as a giant organisms of sorts that is capable of producing, eventually, just about any imaginable material object. Obviously, we can't make arbitrarily ordered materials just yet but we're well on the way there, nanoassemblers or no. So, let's take a hypothetical human race 200 years from now and take that as an example of a universal assembler. Clearly, there must be some sort of minimal general assembler as there is a minimal self-replicator. Will that general assembler be a single tiny robot arm picking up atoms like Drexler envisions? Almost certainly not. The informational density required is simply too much for any simgle small assembly of atoms. However, it is easy to envision tiny robot arms that are specific to particular tasks - working around the sticky fingers problem.
      You need to move medium size +2 valence transition metal atoms? Use arm 32-A94. Want to start assembling branched olefins? Use arm 22-C543. A general purpose assembler is probably going to more closely resemble a factory than a cell when all's said and done.

      Drexler's purely mechanical approach to nano is, IMO, rather naive towards how messy real chemistry is. These robot arms I mention will probably look more like tethered enzyme complexes than anything out of a car factory. Smalley is correct to an extent - Drexler's vision is way too overoptimistic. However, I do think that some sort of assembler tech will be available within the next century.

  105. Yeah but then... by garrulous · · Score: 1

    you just whip out your sharpie and disable their not-so-clever protection schemes.

  106. If you read the article.... by malakai · · Score: 2, Informative
    you would see that Dr. Drexler does indeed show homage to Feynman...

    From the above linked article:
    These spring from Richard Feynman's famous 1959 talk, "There's Plenty of Room at the Bottom," which envisioned using productive machinery--factories--to build smaller factories, leading ultimately to nanomachines building atomically precise products.
  107. MOD PARENT UP/NANOS PLEASE REBUT PARENT by Cryofan · · Score: 1

    I myself am a cryonicist, and so, therefore, I sure do hope Drexler is right. But you have a good argument!

    --
    eat shiat and bark at the moon
  108. Hold on by nnnneedles · · Score: 1

    You guys are actually discussing tiny nanobots constructing something the size of a Ferrari?

    Wake up. It will never happen.

    Not just because it's incredibly far out, but it's such an inconvinient way of constructing, that it would cost you billions of times more money and/or take billions of times longer.

    Self-replicating nanobots? I'll believe that when I see self-replicating, normal-size robots.

    --
    Will code a sig generator for food
    1. Re:Hold on by Anonymous Coward · · Score: 0

      You guys are actually discussing tiny [DNA molecules] constructing something the size of a [blue whale]?

      Wake up. It will never happen.

      Not just because it's incredibly far out, but it's such an inconvinient way of constructing, that it would cost you billions of times more [plankton] and/or take billions of times longer.

      Self-replicating [DNA molecules]? I'll believe that when I see self-replicating, normal-size [animals].

  109. here's your fingers by Anonymous Coward · · Score: 0
  110. My Money's On Smalley by Valdrax · · Score: 1

    Smalley knows what he's talking about. Drexler never once explains exactly how he expects to hold onto these atoms & molecules without running into problems from interaction between the fragment to be manipulated and the mechanical arm's substrate. This is the "sticky" and "fat" fingers problem. The arm and the base for the reaction will have to be made out of physical, real-world materials that will interfere with the reaction.

    Furthermore, Dexler seems to live in a fantasy world where Heisenberg's Uncertainty Principle doesn't exist and the position and momentum of atoms can be precisely measured and controlled. While it is theoretically possible to control a reaction if you can move atoms with perfect precision, you simply cannot do this, especially at any reasonable temperature, and exactly how useful is a process that can only happen in a vacuum at near absolute zero? The energy involved in working at room temperature will make atoms jump around wildly and uncontrollably. (Creating pre-cooked food, my arse...)

    Then we get into the problem of actually precisely positioning the mechanical arm. It's made out of real-world materials too, and yet it must be perfectly moved on an atomic scale for this to work. What larger mechanism is capable of doing this? We've shown that we can nudge atoms slowly with an electron beam, but we have yet to demonstrate that we can control a reaction at that scale, and I doubt that we ever will. I'm positive that it's absolutely impossible to do at room temperature.

    --
    If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
  111. nanite whoring by kaoshin · · Score: 1

    "Thank you for choosing value rep. Please make a selection." ...
    Thank you for choo
    thank you for choosi
    thank you
    thank you f
    thank you for choosing value rep.
    *picks up bullets*

    I got your insect right here shodan.

  112. Possible always beats Impossible by carcosa30 · · Score: 2, Insightful

    Nanotech assemblers already exist. There are billions of them inside your body. They're called cells.

    It may well be that we will use tailored DNA to bootstrap nanotechnology. Cells are already very efficient organisms; perhaps it would be possible to grow them in an artificial matrix, with their DNA programmed so that they would express out nanomachines of arbitrary construction. Or perhaps just parts.

    Which is more difficult-- understanding of DNA to the level where that would be possible, or doing it from scratch? My guess would be the former.

    --
    Intolerance for ambiguity is the mark of the authoritarian personality.
  113. Not under today's Governments by Asmodean · · Score: 1

    There is no way in hell that any of the worlds governments of today would let a citizen have access to advanced assemblers capable of producing a ferrari.

    If it can produce a ferrari, it can produce a 20 kiloton Nuke, or other dangerous items. Just have the 'bots scrounge the right atoms from the dirt under your property.

    And if you can assemble then you can probably disassemble as well. Neighbor piss you off? No problem just send a cloud of 'bots to go disassemble him. They'll never find a body.

    Want to rob a bank and get away with it? Just change your appearance to match someone else, make sure the cameras get a good look at you.

    I'm sure you can think of a million other abuses of such technology. It's too bad too because it would have awesome potential.

    --
    It's a good thing the world sucks or we'd all fall off.
  114. I'd take that bet by Noren · · Score: 2, Informative
    If I had to bet, I'd say that Smalley was right. Drexler adamantly refuses to address the issue. Smalley points out a fundamental flaw in all mechanical methods, which Drexler then says was about only a subset of mechanical methods.. those which he's not using. When Smalley points out his claim was general, Drexler pretends the original arguement applied only to the subset and is therefore a strawman.

    If you strip away the fancy words (and shamelessly simplify), this becomes much more obvious:

    Drexler: We can build structures with atoms exactly where we want them, within reasonable limits.

    Smalley: Your fingers are too big and sticky. Any possible apparatus you can build will inherently have fingers too big and sticky. It won't work.

    Drexler: We wouldn't use "fingers," we'd use a apparatus of molecules designed for the purpose that are not named "fingers".

    Smalley: You're just renaming your apparatus to avoid the issue. Any mechanical apparatus will have these problems regardless of what you name it.

    Drexler: I didn't call my apparatus "fingers" and your original arguement mentioned "fingers", so that is a strawman argument. Besides, living cells do something sort of like this all the time.

    Smalley: Ah, but that's chemical, not mechanical, and reactions are very specific. The mechanical part of your proposal is where the problem is- you can't just shove things together and expect to get what you want.

    And so forth...

    The argument is about putting molecules together mechanically, as Drexler proposes. Drexler repeatedly refuses to address this point. I agree with Smalley that mechanical positioning, as Drexler advocates, is an inherently very limited method.
    1. Re:I'd take that bet by MarkusQ · · Score: 1

      *laugh* I can't imagine either of them talking the way we're putting words in their mouths, but since I started it I can't really complain.

      The semantic issue isn't really "fingers" vs. "an aperatus of molecules", it's more "chemical" vs. "mechanical".

      If at first you define "chemical" reacions to be ones that generally take place in a solution between molecules that meet at random angles and at random speeds, etc. then catalists and solvents are amazing (and important) things, while "mechanical" interactions seem to have nothing to do with it. When you finally get into the nitty gritty of what makes a catalist, you find that it is about mechanical things like aplying forces, constraining rotations, etc. When you understand the role of solvents you see that they are important because they do mechanical things like moving reactants around and possibly acting as co-factors for the catalists.

      So then you have the option of redefining "chemistry" to be about reactions between molecules regardless of where and how they take place, and you can consider different ways of moving things around, aplying forces, constraining motion, etc. This is the leap Drexler has made but Smalley (I infer) has not.

      The whole "fat/sticker" fingers thing is a gross over generalization of how atoms behave. Sure, some are very "sticky" (e.g. charged, or radicals, or just highly reactive due to unfilled orbitals), but it is also possible to design very non-reactive surfaces. Likewise, some structures are very "floppy" and therefore "fat" when you try to position them, but others are far stiffer (or actively track) and can be used for fine positioning.

      The argument is about putting molecules together mechanically, as Drexler proposes. Drexler repeatedly refuses to address this point. I agree with Smalley that mechanical positioning, as Drexler advocates, is an inherently very limited method.

      But it is literally the only method we've got. Even making soup requires you to (mechanically) bring the ingredients into proximity. Enzymes, etc. are just useful pre-existing means of mechanically applying various forces to speed up a reacion. Why stop there? I don't see it as Drexler refusing to address the point as much as his critics refusing to acknowledge his response.

      -- MarkusQ -- MarkusQ

    2. Re:I'd take that bet by Noren · · Score: 1
      There are a lot of things that can act as catalysts, but nearly always it involves a chemical reaction with the catalyst, so that a reaction like
      A+B--- / ---> AB
      where A and B don't react (or react too slowly) with each other becomes something like:
      A+B+C ---> AC+B---> AB+C
      where both of the above reactions are faster and C ends up the same as the start. The net effect is A+B--> AB, even though that doesn't happen directly. C does undergo chemical reactions- as almost all catalysts do- it's just that the net amount of C is unchanged that makes us call it a catalyst instead of a reactant or product. I have gotten into the nitty gritty of designing catalysts and it indeed involves all of the factors you mention- but the chemistry at the site is generally most important and decided first, with the other factors also important but more easily adjustable.

      Drexler has focused on one aspect of the problem and decided that it can do everything. When your only tool is a hammer all problems look like nails.

      The whole "fat/sticker" fingers thing is a gross over generalization of how atoms behave. Sure, some are very "sticky" (e.g. charged, or radicals, or just highly reactive due to unfilled orbitals), but it is also possible to design very non-reactive surfaces. Likewise, some structures are very "floppy" and therefore "fat" when you try to position them, but others are far stiffer (or actively track) and can be used for fine positioning.
      Smalley demonstrated that this is false. Perhaps you can avoid having highly reactive groups near your active site, but hydrogen bonding, Van der Walls forces, dipole-dipole interactions, etc. and other 'weak' interactions simply cannot be ignored on this scale. There exists no atom with properties like this for 'fine positioning'. All atoms near other atoms interact... that's fundamental.

      It's true that proximity and steric effects can allow reactions to happen- but that's a far cry from the molecular machinery that Drexler claims is possible.

    3. Re:I'd take that bet by MarkusQ · · Score: 1

      but the chemistry at the site is generally most important and decided first, with the other factors also important but more easily adjustable.

      Drop down a level in your thinking. From a physics perspective, "the chemistry at the site" disapears. It is, after all, just an aproximate way of describing the forces, charge distribution, etc.

      The only reason it apears to be the most important factor is because we look at it that way, and have tools to deal with problems effectively when looked at from a chemical perspective. If we had a bit more omph in our computers (or better QM software) we could elliminate the chemical perspecive all together and just talk about the forces on various charged bodies. All we'd really need to take into acount is 1) charge, 2) mass, 3) the fact that electrons are fermions. Everything else a consequence.

      hydrogen bonding, Van der Walls forces, dipole-dipole interactions, etc. and other 'weak' interactions simply cannot be ignored on this scale.

      No one is saying they can be ignored. For that matter, Drexler doesn't ignore them (see Nanosystems for examples). You can't ignore friction when designing a car but that doesn't mean that the existence of friction makes cars impossible.

      All atoms near other atoms interact... that's fundamental.

      Right. But not all interactions are the same. Some are atractive, some repulsive, some strong and others weak, some highly dependent on angle or distance and others not as dependent. This is the stuff of which engineering is made. It's a known art. Build huge tables of interactions and all the data you can get on them, and let the designers pick and choose the combination that works best for them. Rinse, lather, and repeat.

      -- MarkusQ

    4. Re:I'd take that bet by Noren · · Score: 1
      Drop down a level in your thinking. From a physics perspective, "the chemistry at the site" disapears. It is, after all, just an aproximate way of describing the forces, charge distribution, etc.
      I don't know how to respond to this. You appear not to know what the word 'chemistry' means. Chemistry is reality. Methods used to describe chemistry are approximations, as are methods used to describe physics. And even now we wouldn't (and don't) describe them as 'charged bodies'- that's a terrible classical approximation. To even get things very roughly approximate you're going to be calculating wavefunctions! If you want the best case model of the system, you'd want to go to full description of orbital space (complete basis set limit, ideally, but 'settle' on something like d-aug-ccPV6Z) with complete description of electron correlation (Full Confuration Interaction) and use a fully relativistic Hamiltonian, describe everything within, say, 10 nanometers and simulate this dynamically at finite temperature for, say, a nanosecond? I'd estimate current computers are at least 50 orders of magnitude too slow to do that.

      Much of current computational chemistry is done from first principles (ab initio methods) though Density Functional methods and others involving a small number of parameters(such as some plane wave methods) are also in use- but these are not easy problems and throwing more computational speed at them only gets you so far. And yes, one of the common compromises is to only simulate a small area near where bonds are forming, or the 'active site'.

      It's a known art. Build huge tables of interactions and all the data you can get on them, and let the designers pick and choose the combination that works best for them. Rinse, lather, and repeat.
      That's combinatorial chemistry, and it's useful, but it's been around for a while and no one claimed it was a 'nanofactory'. That description is nothing like the nanomachines alleged to be possible. Again we're back to renaming something already known with a 'cool' name and pretending to have invented it.
    5. Re:I'd take that bet by MarkusQ · · Score: 1

      Re-ordering things a bit (but I hope not changing the meaning in any way):

      • Me:Drop down a level in your thinking. From a physics perspective, "the chemistry at the site" disapears. It is, after all, just an aproximate way of describing the forces, charge distribution, etc.

        You:Chemistry is reality...Methods used to describe chemistry are approximations, as are methods used to describe physics... To even get things very roughly approximate you're going to be calculating wavefunctions!

        It sounds like you are meaning the same thing that I am, though we disagree on the exact terms. When I talk about "Chemistry" as a field of study I mean what you appear to mean by "methods used to describe chemistry." I would not say that "chemistry is reality" since it is clearly (to me) an aproximation that is only valid over a certain range of physical conditions (in fact, I would go so far as to say that 99% of the universe (by mass) is in a state where "chemistry" doesn't apply for one reason or another).

        But we would both agree that physics provides a more generaly aplicable aproximation. Correct?

      • simulate this dynamically at finite temperature for, say, a nanosecond? I'd estimate current computers are at least 50 orders of magnitude too slow to do that...but these are not easy problems and throwing more computational speed at them only gets you so far.

        I'm not claiming it would be easy, or that we know how to do it now. But that is a far cry from Smalley's claim that it is impossible in principle.

      • Me: It's a known art. Build huge tables of interactions and all the data you can get on them, and let the designers pick and choose the combination that works best for them. Rinse, lather, and repeat.

        You:That's combinatorial chemistry, and it's useful, but it's been around for a while and no one claimed it was a 'nanofactory'. That description is nothing like the nanomachines alleged to be possible.

        You're confusing the means with the end. Using something very much like combinatorial chemistry (though much more difficult) it may someday be possible to design and build Drexler's dodads. This does not mean that the dodads are combinatorial chemistry, any more than dog poop is a dog, simply by virtue of being produced by a dog.

        Or to choose a more dignified analogy, consider a computer. It is the product of an enormous amount of electrical engineering, and yet no one would say that it is "just another name for electrical engineering". I would not dream of speculating if computers or ellectrical engineers are more useful in general (esp. since my wife is a EE and reads /.) but I would claim that they are different things that are both very useful in very different ways.

      -- MarkusQ

    6. Re:I'd take that bet by Noren · · Score: 1
      But we would both agree that physics provides a more generaly aplicable aproximation. Correct?
      No, neither chemistry nor physics are approximations, the words refer to aspects of reality. Approximations are made by people working in those fields out of necessity or ignorance, but that does not mean the processes as they actually occur in nature are somehow 'approximate'. That makes no sense. The methods that chemists choose to model chemical systems should rationally be expected to be as good or better than those used by the less specifically focused physicists to describe the same system. (Actually, there's a large grey area of physical chemists and chemical physicists, and it's not like the two groups never meet... almost all the time they're using the same methods in the areas where studies overlap.) I refuse to go down the tangent about the composition of the universe.
      I'm not claiming it would be easy, or that we know how to do it now. But that is a far cry from Smalley's claim that it is impossible in principle.
      Smalley doesn't refer to ab initio calculations at all, I'm referring to your tangent on a bizarre way to do quantum chemistry. Your proposal was horribly, horribly impractical but not impossible.
      You're confusing the means with the end. Using something very much like combinatorial chemistry (though much more difficult) it may someday be possible to design and build Drexler's dodads. This does not mean that the dodads arecombinatorial chemistry, any more than dog poop is a dog, simply by virtue of being produced by a dog.
      The alleged end isn't possible, (or rather, I should say that Smalley claims this and Drexler adamantly refuses to address the issue) because all atoms simply are fat and sticky on that scale, and all the engineering in the world will not change that. This can't be ignored- you'll have to tailor the process chemically to use these necessary interactions, like nature does it, and not exclusively mechanically as Drexler proposes. Repeating 'engineering will fix it' as a mantra doesn't address this issue, as you can't 'engineer' atoms to be sufficiently small or sufficiently unsticky.

      The process you referred to would work to do the job of assembling things on the nanoscale- which is one of the goals of nanotech but is not itself nanotech. It would not work to create an object with properties unlike known atoms (such as a nano-machine which does not interact with the target structure other than to deposit an atom.)

    7. Re:I'd take that bet by niftyzero · · Score: 1

      You say: This can't be ignored- you'll have to tailor the process chemically to use these necessary interactions, like nature does it, and not exclusively mechanically as Drexler proposes.

      But Drexler does say that the process will be chemically tailored. He's talking about a combination of chemical and mechanical (positional) engineering.

      So, do you agree that using both chemical and mechanical engineering, we can construct a rich set of molecularly precise objects? (not any object, but a rich enough set to construct computers, robots, etc.)

    8. Re:I'd take that bet by Noren · · Score: 1
      ... then this is just classical chemistry with a 'cool' new name. We can make molecularly precise objects using chemical methods... and have been doing so for decades.

      Once you throw out the generic assembler concept there's nothing new here.

    9. Re:I'd take that bet by niftyzero · · Score: 1
      Cool, I think we are getting somewhere.

      The problem with plain chemistry is that it is very hard to build complex structures to spec, such as circuits.

      Here is a sample application:

      Let's say that you have two kinds of building blocks, one conducting and one not. Each building block is to be placed on a surface and bond to its four neighbors. Basically you want to build a circuit board based on a specified 2-D raster. The building blocks can be mass produced using normal chemistry.

      The building blocks can bond to each-other (north, south, east, west) and to the surface. If you just throw them together, you will get a random pattern. Chemistry did its work, but you got a random, non-functional circuit.

      Now, let's say you have an "assembler" that can be fed these two blocks in a programmable fashion. The assembler also has 2-D positional control with a 1nm resolution. And let's say that the blocks are 5x5nm. You will then be able to place each conducting or non-conducting block at its programmed position. And you can do so without a significant chance of the wrong block getting attached at each raster point.

      The addition of position control (the assembler) gives you the ability to create complex, programmed "polymers" at one level above the basic building blocks.

      Now let's say that you have 10 or 100 types of building blocks. The dimensions and connecting edges are compatible, but the functions are different. The assembler lets you arrange these in programmed patterns. With the right blocks, you can create machines, computers, etc...

      I think Drexler set himself up for criticism by sometimes talking about atom-by-atom construction. This is a much harder problem than the building-block scheme.

    10. Re:I'd take that bet by Noren · · Score: 1
      I agree that 5nm by 5nm blocks are mechanically maneuverable in principle. Some of this is a matter of perspective, actually- where the engineers (and some physicists) see 'room at the bottom', the chemists see 'room at the top' and are scaling up chemical reactions to the multiple nanometer scale instead of trying to scale down mechanical apparatus to the sub-nanometer scale. There's a lot of work in self-assembly of macromolecules at this scale going on, though it's (at present) controlled chemically rather than mechanically.

      At some point the two scales will meet (and are doing so to a very limited extent today), when the growing scale of chemically developed macromolecules meets the shrinking scale possible for mechanical manipulation.

      On the other hand, the atom-by-atom assembly by mechanical methods claim is never going to happen, and you're quite right that that claim is where Drexler's problems are. There's a lot of good work to be done with small-scale mechanisms, but that doesn't mean that they're the way to solve all problems. Overhyping an area of science like this can lead to short-term interest in that area but is bad for other, competing areas (and is a recipe for disappointment in the longer term.)

    11. Re:I'd take that bet by niftyzero · · Score: 1

      I think the promise of molecular nano-technology is programmable construction. Self-assembly is nice, but it still gives you a regular structure rather than a programmed structure.

      For example, lithography drives the computer industry. There is no way you can create structures on the order of complexity of a silicon chip with pure self-assembly. You need positional control.

      An programmable molecular construction platform, which is what I would call an "assembler" would give you the power of lithography on the nano scale.

      Also, I wouldn't say that atom-by-atom will never happen. There might be a rich enough set of [reaction + mechanical trajectory] combinations that will work. It's a much more difficult problem, but I would not say "never".

  115. Re:I never understood how it was supposed to work. by jafuser · · Score: 1

    After a google search to verify the non-existance of the word, I hereby give freely to the world:

    roboribosomes

    Now that's just fun to say out loud =)

    --
    Please consider making an automatic monthly recurring donation to the EFF
  116. AIDS only spreads in body fluids by Chemisor · · Score: 1

    To contract AIDS (or rather HIV, as I have not yet seen the connection proved to my satisfaction), you have to exchange bodily fluids with the infected person. That means a blood trasfusion, or sexual intercourse. Since most of us only have sex with a very limited number of people (and those who are on Slashdot probably don't have sex with anybody :), the rate of infection is quite slow and limited. Nevertheless, it is currently the rage in Africa, where apparently the people are more promiscuous than in our prudish western societies.

    Consider the nanoplague now, which is not limited to this form of infection. Viruses and bacteria have great difficulty surviving outside the host for a long time. Excepting anthrax spores, most biological diseases die off in a day or less when deposited on any dry surface. A nanoplague can manufacture spores that would survive indefinitely and can be spread by touch alone if generated on the fingertips. Such spores will lie dormant on every doorknob the infected person has touched and will infect EVERYONE who touches it afterwards with nearly 100% efficiency. The entire world could be infected in a few months in this manner without anybody noticing.

  117. Re:fp by Anonymous Coward · · Score: 0

    funny

  118. Possible but limited by Peldor · · Score: 0
    Sure molecular assemblers are possible, but they will probably be quite limited. A universal assembler, a single nanobot that can build anything from component atoms, is likely impossible. What we'll get are assemblers much like our current machines, that is, highly specialized. Assemblers will put one specific atom or functional group in one site on another specific molecule. Then pass the product off to another assembler.

    To build something really complex, you'll actually be using a whole host of assemblers each designed for a specific task.

  119. Arguing past each other... by aridg · · Score: 1

    This dialogue was frustrating, because these two smart scientists seemed to be arguing past each other, about entirely different things.

    Drexler seems to be saying "Molecular assemblers are possible, and you can't prove me wrong."

    A lot of slashdot posters agree -- "Smalley has no proof that this is impossible".

    And, if you look at the question from that perspective, Drexler and the posters are right, largely because it is *very* *very* difficult to show that something is "impossible".

    But Smalley is actually arguing something else: he's saying "I've analyzed this proposal for building a molecular assembler, and let me tell you, it won't work!". And, as far as I can tell, he's probably right. Drexler and the posters, of course, say that Smalley is creating (and demolishing) a straw man. A *real* molecular assembler will work differently.

    *I* say: OK, you say that was a straw man, so tell me about the REAL man. Let's see the proposal that *will* work. Don't give me arguments that say "enzymes can do it, so therefore we can too". Give me an honest design proposal. (And, while you're at it, give it to someone smarter than I am -- someone like Smalley.)

    Then we have a starting place, and we can ask: Does this work? I suspect that a realistic proposal will fall prey to many of the problems that Smalley describes, but who knows?

    But without a starting proposal, who knows what we're even talking about? We're not on the same page... Heck, we're not even in the same galaxy.

  120. Re:Offtopic: entropy by Noren · · Score: 1
    Well, the process must be one where enthalpic(potential energy held in chemical bonds, etc.) gains exceed entropic losses (and putting two molecules together is pretty much guarenteed to be entropically unfavorable.) The reactants have to be that much more enthalpically unstable than the products are for the reaction to proceed. This is true for 'normal' chemistry, and will also be true for nanomachine chemistry.

    This is doable in the abstract, we know how to make higher energy reactants as building blocks, but it does make selection of reactants and products for hypothetical nanomachines trickier.

  121. Not totally fallacious by Rupert · · Score: 1

    If someone had argued, back in the 1960s, that we would *not* be ruled by AIs in the 1980s because you'd need a computer capable of 4 million instructions per second and small enough to fit on a desk, then they would be guilty of the same fallacious arguing that MarkusQ accuses Smalley of in the grandparent post.

    It doesn't mean that Drexler is right. It just means that Smalley needs some better reasons why he's wrong. Either that, or time will tell. And usually, unless the 2nd law of thermodynamics is violated, the person claiming that something is possible turns out to be right.

    --

    --
    E_NOSIG
  122. Drexler is mad scientist by chillax137 · · Score: 2, Insightful

    He's always supported nanotechnology since he was a student at MIT, but many people have pointed out that he goes about it the wrong way. He's made a lot of efforts to further the science, but he tries to do it in one large leap. A lot of the academic community see him as a pseudo-scientist who is way too optimistic. He's gained a lot of his popularity from saying things that are shocking but don't have much credibility to them.

    --
    chillax137
  123. Energy source by Mister+Attack · · Score: 2, Insightful

    OK, lots of people have read "Prey" or one of the other Shiny! Exciting! Books! that talk about the "Gray Goo problem". Simply stated, this is that nanoassemblers which are trained to self-replicate could potentially go bonkers and start turning the entire planet into more assemblers. As Homestar Runner might put it, "That's just ridiculous" -- and yet this is what some people lose sleep over! The reason that nanoassemblers will never be able to replicate in an uncontrolled environment, and therefore will never take over the world, is that they need energy to function. Lots of it. Breaking pi and sigma bonds can be ridiculously expensive, requiring several eV of energy in some systems. Pulling a carbon out of a single-walled nanotube takes over 10 eV. Where does the energy come from? Absent a large and complex digestive system, the assemblers will have to be fueled ahead of time or provided with a simple energy source along with their raw materials. These robots will not be able to find the energy they need to keep going in the wild. That's why Smalley's not worried about runaway nanobots. The extreme difficulty of doing "machine-phase chemistry" is another good reason, by the way -- assuming machine-phase chemistry is even possible, how are the nanobots supposed to create a clean enough environment to do their work in the wild? If machine-phase chemistry can be accomplished at all, it will be a much more complicated affair, I think, than Drexler would have us believe.

    1. Re:Energy source by Anonymous Coward · · Score: 0

      Aether?

  124. energy from chemicals by levl289 · · Score: 1

    Make gasoline, or hydrogen at home, and then *make* the converter to turn it into electricity.

    So yeah, space is really the only thing you'd need, and even then, just fly off to mars in your own custom-built spaceship. Really the only thing that'll cost money (possibly) are the directions for your atomic assembler.

    --

    Q: What do you think about American Culture?
    A: I think it's a good idea.
    (adapted from Gandhi)

    1. Re:energy from chemicals by Galvatron · · Score: 2, Interesting
      Yeah, um, how do you think you're going to get the energy to "Make gasoline, or hydrogen at home?" Thermodynamics still applies when you're dealing with nanobots, you can't get more energy out than you put in.

      Neil Stephenson's Diamond Age is probably a more reasonable assesment of where things will go. People will still be employed in the design of new machines, and will be able to afford better pieces of land, and more electricity (Stephenson also suggested that perhaps handmade items would become status symbols). The (unemployed?) masses will live in unparalleled comfort from a historical perspective, being well clothed, fed, etc.

      --
      "The question of whether a computer can think is no more interesting than that of whether a submarine can swim" -EWD
    2. Re:energy from chemicals by cornjones · · Score: 1

      Besides space the thing that is going to cost is material. You will still need to put in a mass of material to be rearranged into your ferrari. that becomes the true currency. In the aforementioned Diamond Age, iirc, there was a matter "tap" in the house and it was metered like your electricity, you could use as much matter as you could afford to make anything you wanted to make.

    3. Re:energy from chemicals by femto · · Score: 1
      If the replicator includes a 'scavenger', the only material input will be some carbon containing matter (such as some grass clippings).

      Also, one of the supposed advantages of molecular assembly is that there is no waste, so material requirements are minimised.

    4. Re:energy from chemicals by Galvatron · · Score: 1

      Why carbon? The parent is right, you will need to pay for access to rare elements (such as platinum, for example). Carbon, as you say, is so easy to find as to be effectively free, but not all elements are quite so plentiful.

      --
      "The question of whether a computer can think is no more interesting than that of whether a submarine can swim" -EWD
    5. Re:energy from chemicals by s0l0m0n · · Score: 1

      I agree with your comments about the Diamond Age. Neal Stephenson is insightful and fun to read to boot. A non fiction work of his, In the beginning there was the CLI is available online ;) A good read, and pertinent to the discussion of tanks and Ferrari's.

      I've personally seen the demand for handmade objects over machine made ones. I hand make custom knives and swords, and even as a nameless competitor I can command significantly more for a knife than you would typically see in a store.

      A friend of mine up in Seattle sells machine made swords fabricated by a former Boeing machinist by the name of Angus Trim.. You can see his work here All Saints Blades. Very nice stuff, and in my opinion some of the best machine made swords out there. These swords run about 350-550$, with some aftermarket customization that might take them up towards 750$.

      When you look toward the finer hand made blades, you'll notice a steep step in price. Check out this rapier by Kevin Cashen, an American Bladesmith's Society mastersmith. IIRC, this went for about 3000$, and would probably be more now.

      And for those of you who are fond of Katana (c'mon, Fanboy, I know you're out there), look at Howard Clark's work Here. Also an ABS mastersmith, Howard makes katana's that can bend a into a full U before seriously warping.. An article documenting that, and Howard's swords is at the Swordforum. In addition to the suffering that the blade alone would set you back (about $3K), a fully polished and mounted blade would run you upwards of 6000$.

      Of course, you can get hand made swords for cheaper, but they are going to be made in China, or else where under dubious working conditions (smithing is tough enough work, even when you get paid what you should for it), and not of the same level of craftsmanship. You can take a look and see what I mean.

      The demand for hand made goods is all ready rising, and I predict that this trend will grow as more of the goods and services are provided to us by machines.

    6. Re:energy from chemicals by cornjones · · Score: 1

      I would assume there would be a way to "feed" the machine. You would still be bound by the amount of matter you could feed it. One interesting thing that this brings up is that there would have to be theft prevention measures taken at parks and forests. Otherwise everybody would strip the park of all matter that isn't to heavy to move..

    7. Re:energy from chemicals by Galvatron · · Score: 1

      However, correct me if I'm wrong, but you're talking about handmade items that are generally superior in quality to the machine made items, right? In Diamond Age, on the other hand, the handmade items were of inferior quality. Apparently they used to make handmade cars in Italy. They were originally of superior quality, and charged a high premium. As the machines got better, and cars got more complex, the handmade cars became worse and worse relatively, but charged ever increasing premiums as labor became more expensive. Obviously, they're not around anymore.

      --
      "The question of whether a computer can think is no more interesting than that of whether a submarine can swim" -EWD
    8. Re:energy from chemicals by s0l0m0n · · Score: 1

      Generally superior, absolutely. Most of that superiority is in the last level of fit, finish and decoration. The high end collector's market isn't willing to pay for that level of sophistication in a machine made item.. A machine could be made that produces fine swords (and the swords that are machine made currently are some best functional sword), and many lower end knives made primarily by machines are very nice, but they do not command the higher level of finish and price simply because they are machine made.

    9. Re:energy from chemicals by knobmaker · · Score: 1

      If you're going to accept the idea of molecular assemblers, why not accept the idea of atomic assemblers? Then there will be no rare element shortages.

    10. Re:energy from chemicals by Galvatron · · Score: 1
      Why not? I'll tell you why not. You know what it's called when you take protons out of an atom's nucleus, thereby transforming one element into another with a lower atomic number? It's called nuclear fission. Conversely, adding protons is known as fusion. These operations take tremendous power, several orders of magnitude more than any mere molecular reconfiguration. There's a reason that the force which binds molecules is called the "weak force," while the force binding nuclei is called the "strong force."

      Now, far be it from me to call anything impossible, but the existence of molecular assemblers in no way implies the existence of atomic assemblers. We're talking about a whole new ballgame there.

      --
      "The question of whether a computer can think is no more interesting than that of whether a submarine can swim" -EWD
  125. A much lower startup cost. by Chemisor · · Score: 1

    > Well, you could have a disgruntled engineer construct a rogue
    > nuclear weapon and use it to destroy a city.

    Fission materials are not that easy to obtain. Sure, some eccentric billionnaire could probably purchase them for a few million dollars, but for most people it is simply not possible. Most engineers would have no idea how to go about purchasing enriched uranium, nor would they have enough money to pull it off. Even Osama Bin Laden, with all his money and all his connections, has evidently not been able to procure any nuclear materials. And if he can not do it, how can your average disgruntled Joe Engineer?

    Furthermore, the threat is much lower. A nuclear explosion in a major city might cause millions to die, if he is lucky. The death toll for Hiroshima was much lower. A nanoplague could wipe out entire nations! Quite a difference in scale, don't you agree?

    > A case could be made that by the time a person
    > gains the education to be able to construct such
    > a device (nuclear weapon/rogue nanomachine),
    > that the people with the means and the mental
    > issues to cause such destruction/death will be weeded out.

    Really, now. Were there really no scientists working on biological weapons in Iraq? The Unabomber was an educated man too, you know. Furthermore, it only takes ONE, so I wouldn't put too much faith in this argument.

    > And if you read Drexler's book Engines of
    > Creation, there are proposed systems that could
    > be constructed to keep check of nanomachines.

    And how would such a system detect an inert spore sitting on a doorknob in the neighbourhood with a few million dust grains from which it is externally indistinguishable? Will you decompile every dust particle to see if there is anything interesting in it? Will you decompile every grain of sand under your feet, every skin flake, every dust mite? If Saddam Hussein has no difficulty hiding tanks in the open desert, do you really think it would be difficult to hide something trillions of times smaller amid similar items?

    Perhaps you meant to install such inspectors inside the body? How will they be able to tell an plague body apart from an erithrocyte, if it were disguised as one? Will it even be able to detect a millimeter thin graphite antenna within solid bone? Will it be able to stop the poison factories in time when that antenna receives a signal to blow, if it may take only nanograms of a strong poison to kill you?

    > The key is to focus on developing the defensive
    > systems as quickly as possible, to minimize the
    > time period that nanomachines could exist
    > unchecked in the wild.

    But they are not "in the wild". You are thinking of the "grey goo" threat of runaway replication, not about an intentionally disguised, hostile, nanoscopic entity, which can compile any shell it chooses, like a perfect chameleon. Think about a threat that comes from a hostile mind, not from negligence.

    > Pehaps the number one method of preventing such
    > occurences is to try and find the way to
    > minimize the number of people with such strong
    > hatred of other people as to be willing to do that.

    Very funny. That such people exist and always will, may be illustrated by a random post at nanodot. Check out the first comment at http://nanodot.org/article.pl?sid=03/11/24/0521230
    And in the meantime the Israelites keep killing the Palestinians and vice versa. The Chechens keep killing the Russians. The Serbians keep killing the Bosnians. The arabs keep hating the europeans. The African nations all hate each other are in constant war. And, of course, these days everybody abroad hates the United States too. And, since I am living there, perhaps you can understand my concern?

    1. Re:A much lower startup cost. by Saige · · Score: 1

      I'm not claiming your average Joe Engineer would be able to get all the materials together to build a nuclear weapon - and similarly, I'd expect that your average Joe Engineer won't have the means to construct nanoviruses. At least not for a long time. For a significant time period, I'd expect the people with the access to the tools and the knowledge to do so will be small in number, and even then not exactly free to do as they wish.

      And yes, eventually extremists will have the means to start researching the ability to create nanoviruses - but how long after the technology is out there? Iraq and Al Queda were working on chemical and biological weapons - how many decades after the US and other less rogue regimes/groups developed them? It's the same with nuclear weapons - the US had them in the 40's. Only now are they starting to get into the hands of countries that may not have the best motives. It doesn't make sense to assume that as soon as the large corporate/US government lab have the means to create nanoviruses that rogue elements will be able to do so.

      Still, most of this is meaningless speculation - disasterbation, if you will. We don't know what would be involved in constructing one, what kind of limitations might apply to nanoviruses, and what kind of means there may be to detect/destroy them. Perhaps by the time such creations as really in the realm of possibility, something like the proposed "utility fog" may be developed, and able to keep such particles away. Or some sort of nano-membrane developed that actively inspects each and every atom/molecule allowed to pass through.

      I don't claim what you propose won't happen. I do think that it is still far enough off that we cannot determine how likely/unlikely such an event is, and cannot adequately figure out means to defend against such instances.

      --
      "You know your god is man-made when he hates all the same people you do."
  126. Something useful should have been built by now by Animats · · Score: 1
    There ought to be something useful you can assemble at the molecular level, atom by atom. Ever since IBM used a scanning tunneling microscope to move xenon atoms around, it's been clear that you can do some things that way.

    But so far, nobody has built much useful that way. Positioning xenon atoms works well because they're inert and don't bond to anything. Breaking and attaching bonds without damaging the working tip is tough.

    Obvious things to build include read and write heads for molecular recording. You get to pick the recording medium, so you can pick materials and bonds compatible with the manipulator.

    STMs manufactured by MEMS techniques exist now, so there's reasonable potential there.

  127. Never once? by MarkusQ · · Score: 1

    Drexler never once explains exactly how he expects to hold onto these atoms & molecules without running into problems from interaction between the fragment to be manipulated and the mechanical arm's substrate.

    Seems to me he's been explaining it for years. In short, the part would be bonded (either covaliently or ionicly) to the arm, with bonds that were designed to be strong enough to "hold" the part but much weaker (w. respect to forces on at least one axes) than the internal bonds on the part. When it was in the proper position with respect to the destination assembly, forces would be applied to create bonds between the part and it's new home. Now the whole thing is bonded together (including the arm). The arm would be freed by applying different forces (at right angles, say) to break the bonds between it and the part.

    Dexler seems to live in a fantasy world where Heisenberg's Uncertainty Principle doesn't exist and the position and momentum of atoms can be precisely measured and controlled.

    Nuts. He has addressed this point multiple times. Besides, in what follows you are talking about thermal, not quantum, positional uncertanty.

    While it is theoretically possible to control a reaction if you can move atoms with perfect precision, you simply cannot do this, especially at any reasonable temperature, and exactly how useful is a process that can only happen in a vacuum at near absolute zero?

    Cells do it at room temperature. So nature, at least, doesn't agree with you.

    The energy involved in working at room temperature will make atoms jump around wildly and uncontrollably. (Creating pre-cooked food, my arse...)

    Creating (frozen, say) pre-cooked food should be no different than creating raw food at the same temperature. And note that most of our food is created by creatures that do their work at room temperature, and (at the smallest scale) assemble every molecule with every atom in the right place. The fact that they get sloppy as the sub-assemblies get larger has more to do with the cost/benifit (to them) than to any technical limits.

    -- MarkusQ

    1. Re:Never once? by molyman100 · · Score: 1

      The advances in chemistry alone needed to design bonds strong enough to hold parts yet still be weaker than the parts own internal bonds would make nanomachines nothing but simple toys. Instead of nanomachines we could just make a new liquid made of 80% nitrogen and 20% oxygen with bonds designed with just the right energy to be able to burn in a car engine, and then leave just N2 and O2 in the exhust.

    2. Re:Never once? by MarkusQ · · Score: 1

      The advances in chemistry alone needed to design bonds strong enough to hold parts yet still be weaker than the parts own internal bonds would make nanomachines nothing but simple toys. Instead of nanomachines we could just make a new liquid made of 80% nitrogen and 20% oxygen with bonds designed with just the right energy to be able to burn in a car engine, and then leave just N2 and O2 in the exhust.

      Nuts. The way you make the bonds the strength you want to be is by choosing the atoms on either side and imposing strain (e.g. making them not line up quite right to make the bonds weak, or making them unable to move out of alignment to make the bond weak). You can also make them "switchable" by messing with charge distribution. This isn't something you could do with a liquid of pre-specified composition, but would be easy with a solid if you get to specify the structure and composition.

      -- MarkusQ

    3. Re:Never once? by molyman100 · · Score: 1

      Why will the bond between the assembler and the product (or product part) be weakened, rather than one of the other bonds(say on the nanoassembler, or within the product) when strain is imposed? The point I want to make is, once we have the science/tech. to control these things at the molecular level, there will much better uses for the advances than making small machines, we could make antibodies for any virus, kill any bacteria, make catalysts with low energy pathways to break water into pure hydrogen for fuel cells, and we will be limited by only our imaginations. Whose to say that these nanofactories would be the most efficent methods of making the materials that we need.

    4. Re:Never once? by MarkusQ · · Score: 1

      Why will the bond between the assembler and the product (or product part) be weakened, rather than one of the other bonds(say on the nanoassembler, or within the product) when strain is imposed?

      Because it's designed that way. Specfically, you set up a system where a large, stable network of bonds on each side (a diamondoid latice of mostly carbon is the typical example) holds the atoms in question in place--but not quite the right place--to hold to the tool. There are many ways to acomplish this; you might be able to shade the location by doping the two latices, for example, or angle them with respect to each other. The latices provide deep energy wells to stablize the part and the assembler, much deeper than the energy required to break the bonds between them.

      Here's a very loose analogy to help you picture how this would work:

      Take two piles of objects and bind them both into bundles with lots of rubber bands. Now connect them to each other with a single rubber band. Now pull them apart...what happens?

      Or even better, here's an example from real life (not, mind you, an analogy--this is an actual example of the exact effect under discussion):

      Place a small bit of paper on the table. Press down on it with your finger, and then lift your finger off the table, taking the paper with it. Touch it to your tongue, and pull your finger away. Why did the bonds between your finger and the paper break, rather than the bonds within the paper or your finger? (Spit out the paper before answering).

      -- MarkusQ

  128. Capitalism out? by luckyguesser · · Score: 2, Interesting

    Maybe when everyone has their own personal assembler, no one will feel compelled to buy anything anymore. Therefore, the only people in business selling a product will be those selling assemblers. But maybe there will also come a day when the government provides them, too... kinda like phone booths. The phone book could be a directory of things it can make. Anyway, the market would die, but only products. People selling services would still be valued.
    Of course, I can imagine that someone would get the idea to copy a person so that they wouldn't even have to pay for services... just make a servant. I think in this case the government would make a law against copying a human- much in the same lines with the cloning issue today- so as not to devalue the human life ;). Maybe if everyone had anything they wanted at the touch of a button, we would all shift our new attention to creating new and better things, instead of the pursuit of money. Of course, money would have to be kept track of electronically, if it still existed, since it could easily be copied. True, the serial numbers would be the same, but it could be spent before it was caught as a double.

    Well, that's the end of my rant.. tell me what you think. Also, I have a question. Forgive me for not RTFA, but from what the poster said, it seemed to point at the fact that the assemblers simply rearranged matter. On what level does this happen? i.e. would i be able to make an apple if i threw in some raw glucose, pure water, etc.? would i need even that?

    --


    The power of Christ compiles you.
    A Random Blog
  129. Already done by Anonymous Coward · · Score: 0

    Hasn't life already performed this? Will nanotechnology merge with biologist and create living machines for this purpose?

  130. They're Already Available.. by bottlerocket · · Score: 1

    They're already available. Didn't these guys read Michael Crichton's excellent documentary Prey ?

    --
    where the comment ends and sig begins
  131. Clothing Designers by Don'tTreadOnMe · · Score: 1


    So how would this differ from the way clothing designers operate? Clothing designers seem to put out loads of crap at the beginning of their season, which is immediately and cheaply copied by knock-offs and Wal-Mart clothing purveyors.

    But somehow, the clothiers always seem to make a profit, even with cheap imitations coming out almost immediately.

  132. How to steal a nanoplague. by Chemisor · · Score: 1

    In the book "The Diamond Age", a nanoengineer steals a program from his employer by inserting code to create hackleburr-like seeds on the cover of the product (a book). When he handled the book, the burrs stuck to his palm, enabling him to carry it out of the laboratory on his person. While trying to carry eighteen pounds of plutonium out of a secure nuclear weapons factory is ludicrous at best, to carry out a plague spore is not at all unrealistic, since it would be indistinguishable from the rest of the microscopic garbage we normally carry on our skin. To further evade detection, the spore could infect our malicious engineer (remember, the disease is very selective, and will not kill anyone unless he tells it to) and allow him to pass the most thorough of skin examinations. The spore could then interface with his retinal HUD implants for further instructions, use the considerable resources of his body to replicate and generate more spores. He could then select the criteria for detonation. Our Palestinian engineer could, for instance, use the plague's GPS capability to restrict the fatalities to the borders of Israel. Then, all he has to do is set the detonation time, which he could easily do by encoding it into the plague itself, which is capable of accurate timekeeping. Then, one fine morning, everyone in Israel will die within the same five minutes. No accountability. No warning. No trace. No culprits. No more Israel.

  133. I side with Drexler. by bob_jenkins · · Score: 2, Interesting

    I read the letters, and skimmed Drexler's "Nanotechnolgy: ..." book.

    I think Smalley's argument is that for a specific reaction between two molecules, you need something like an enzyme designed specifically for that reaction. The number of possible molecules is astronomical, and the number of pairs astronomical squared.

    I hear you can treat most of molecules mechanically except for a few dozen atoms surrounding the reaction site. That limits it to, let's say, 2^^30 possible molecules, so 2^^60 reactions you need specific enzymes for. Designing any one of those 2^^60 enzymes or reaction paths is feasible. Making an index iwth 2^^60 entries is feasible, given atom-scale memory, although it isn't microscopic. Drexler suggested such an index for diamondoid struts of different sizes in "Nanotechnology: ...". Nanotech is going to make heavy use of indexes like this. Storing all those enzymes, and shipping them one after another to the right place, is going to be SLOW. I suppose you could pipeline your enzyme fetches.

    The real number of enzymes needed is much smaller than 2^^60. To get a self-assembling molecule, assuming you feed it the right basic building blocks, you don't need a universal assembler. DNA limits itself to 4 molecules with a single type of connecting part. Proteins limit themselves to 24 molecules (I don't know if the connecting parts are standardized but I suspect they are). Ribosomes can construct ribosomes, so we already know self-assembling machines are possible.

    An interesting question is, given an assembler that knows how to do some fixed set of assemblies, what can be built? How big a set is needed? The smaller the set, the less work is needed to get the correct configuration for each reaction. Perhaps we need specialized factories for some building blocks with standard connectors, then just a tape-reading assembler that can connect standard connectors? Standards simplify things.

    1. Re:I side with Drexler. by physick · · Score: 1

      RE: To get a self-assembling molecule, assuming you feed it the right basic building blocks, you don't need a universal assembler. DNA limits itself to 4 molecules with a single type of connecting part. Proteins limit themselves to 24 molecules (I don't know if the connecting parts are standardized but I suspect they are). Ribosomes can construct ribosomes, so we already know self-assembling machines are possible.

      There are 20 amino acids that make up all proteins, and they do have a standard linkage between them. The problem is that all the machinery for making proteins comes from an existing cell. The set of proteins the (human) cell can make is a very small fraction of all possible proteins. But you cannot use the cellular machinery to manufacture new proteins because we just don't know what to do. You change one amino acid in a protein and it (not always, but usually) just stops working.

      It would take a VERY long time to work out which single amino acid substitutions produce new working proteins, and we don't yet know what linear sequencec of aa's do what in the final protein.

      So we would be trying to change a few amino acids in a sequence perhaps 100+ aa's long, seeing what shape the resulting protein folds into (if it does actually fold) and then seeing if it does what we wanted it to do.

      I think Drexler is over optimistic about our ability to manipulate atoms. Nature has had a few billion years to make these machines, I don't see us doing any time soon.

    2. Re:I side with Drexler. by bob_jenkins · · Score: 1

      I've always assumed the work of designing new things and coming up with instructions for how to build them would be separate. Only the final instructions would be fed to the assembler. The assembler is only required to translate instructions into things. A ribosome can build a ribosome, but only if it's fed the DNA telling it how to construct a ribosome.

      You're right, having an assembler that can build anything doesn't imply that we'd know what to build with it.

      One of Drexler's big arguments is that amino acids aren't a very friendly engineering medium because it's so hard to predict how proteins will fold. So we should use something else (diamandoid) that behaves predictably. I personally think the combination of lengthy automated search and indexing of known solutions would allow reliable engineering with a more flexible medium than diamond. I'll agree with him and you, though, that proteins are too unpredictable to be the ideal engineering medium. (They're also big and weak and temperature-sensitive.)

  134. Scientists can't use forceful language either. by Chemisor · · Score: 1

    > Maybe I should have been a scientist!

    Then you would never achieve tenure. Scientists have as much, and perhaps even more, political pressure than corporate serfs. Dissenting opinions are hardly tolerated, and the likes of Isaac Newton would never make it nowadays.

  135. goatse? *chuckle* by CiXeL · · Score: 1

    There's Plenty of Room at the Bottom

  136. What Rumsfeld would say... by Chemisor · · Score: 1

    > Smalley has no proof that this is impossible

    "There are known unknowns, that is, there are things we know we don't know. And there are unknown unknowns, which are the things we do not yet know we do not know." -- Donald Rumsfeld

  137. Dick E. Smalley by Anonymous Coward · · Score: 1, Informative

    He's kind of pompus. Ask anyone who's taken his CHEM 102 Class at Rice. He's been like this even before the Nobel prize. He's smart, but at the same time he instantly lost the buckyball/nanotube crown after discovery because (so the rumor goes) his lab was unable to reproduce any of the results others were making in building new structures.

    When I took that class, he made some statement about "spending Daddy's money to buy this book" which instantly pissed off some people. It was funny to watch them start protesting his class because of that one quote though.

    (I've only read from the abbreviated version link, so I'm going to refrain from discussion until I go through the other one)

  138. Of course they are possible by Anonymous Coward · · Score: 0

    Drexler thinks "molecular assemblers" are possible while Smalley denies it.

    Are DNA molecules not protein "moleculer assemblers"? Cetainly it's possible. Nature already does it.

  139. look to Nature by samantha · · Score: 1

    Assemblers exist in nature. Therefore assemblers are possible. Argument ends.

  140. Re:LITTLE GAY AMERICUNTS! by Anonymous Coward · · Score: 0

    I acknowledge your supremacy you good sir.

  141. Arguing past each other by isomeme · · Score: 1

    I think the two of them are arguing past each other. No, I don't think Drexler's simplified thought-experiment version of nanotech -- conceptually, little nanoscale forklifts and welders -- is physically realizable, for all the chemical/QM reasons given. However, useful fine-tuned molecular assembly and even self-replication can be accomplished; in fact, it's happening right now inside the organism typing this message. An existence proof is the strongest kind of proof.

    So the question is not "is nanotech possible?", but rather "will useful human-created nanotech look more like industrial engineering or applied biochemistry?" Personally, I believe it will emerge from a fusion of the two approaches, but still looking more like advanced biochemistry than scaled-down industrial engineering.

    --
    When all you have is a hammer, everything looks like a skull.
  142. What's wrong with big fingers? by Anonymous Coward · · Score: 0
    Smalley: Your fingers are too big. Any robot you build will have fingers too big. It won't work.

    My fingers are bigger than screws. And yet I can twist some appropriately shaped screws into place by sheer finger power (high precision). I can also pick up any screw (low precision) and position it so I can use a screw driver or hammer on it (akin to gunning a molecule into place by using a molecular peashooter or a laser).

  143. Re:I never understood how it was supposed to work. by RLW · · Score: 1

    What happens years from now when that word will be needed but everyone has forgotten that you gave it to us? Make sure you write a paper about it, publish it on the web and make sure that paper gets archived in google and some other major search engines. Better yet, start up an open source project for the purpose of archiving words created before their time.

  144. from an actual nanoscientest by Goldsmith · · Score: 4, Insightful

    What we have here are two different worlds colliding. Drexler is coming at this from the point of view of a theoretical physicist, while Smalley is an experimental chemist.

    Drexler has found certain theoretical processes which would lead to molecular assemblers. The key problem comes from his assumption of complete control over the atoms. Despite his assurances to the contrary, you still have one big fat sticky finger which you've attached your strained structure to. He simply sees that it is possible (of course, if you read his books, there is a glaring lack of chemical calculations).

    Experimentally (I'm a bit biased here, I'm an experimentalist) this is a bunch of crap. No one is anywhere close to doing anything like this. First we need to show experimentally that his idea of creating stressed structures and twisting them apart will work, and no one can touch that right now. How do you create the strained structures? In addition, this would have to be done in vacuum to keep interactions with the environment at a minimum. It would also have to be done at cryogenic temperatures to keep the atoms from vibrating out of place (remember we're relying on two unstable structures). This leads to an expensive and difficult proposal.

    There are a few groups (I know of Wilson Ho's group at UCI - great pictures by the way) which are working on joining one atom with another. It's done under extreme conditions inside a scanning tunnelling microscope, and it's VERY hard. They don't do any twisting, they do the sensible thing and use applied voltages to excite and bind atoms.

    Quite frankly, Feynman and Drexler have been major impediments to experimental nanotechnology for a long time now. There are plenty of interesting, self-assembled structures out there that can do some amazing things which are not related to the assembler idea. There are plenty of good research groups which are dismissed funding in favor of groups which are flailing around in the dark.

    The first thing you learn about nanotechnology is that any intuition about the macroscopic world doesn't carry over. Trying to fit our notions of the rest of the world into the nano-scale world is foolish and wrong. Those strait lines between atoms in a molecule are not always strait.

    Before we try to use nanotechnology to shape the future we need to understand it. Drexler gives the impression that we already do, and that it's time now to move foward, but no one knows how yet; we just don't understand.

    I think it would be wrong of us to say that molecular assembles are impossible. Personally, I think it is possible, and that's why I do this. But to say that they are "close" or to give ANY prediction of when we will see them is just silly. After saying that, let me say something silly and say that although I hope to see nanotechnology come of age in my life, I don't expect to.

    1. Re:from an actual nanoscientest by wintermute42 · · Score: 1

      Thanks for this great post. I think that it is one of the most informative in the long slash dot discussion. In many cases people seem to be arguing for what they want to believe rather than arguing for what seems to be possible in the foreseeable future.

      It is interesting to note that one of Drexler's primary supporter's is Merkle, who also approaches nanotechnology from a theoretical point of view. Drexler et al defend their theoretical approach by claiming that nanotechnology is in the state that fision physics was in the 1930 - theoretical work, leading the way to experimental success. As the parent article notes, there is little experimental evidence to back up Drexler's theories.

      And, by the way, I want to believe too. I've read "Diamond Age" and Ian MacDonald's "Terminal Cafe". Nanomachines are a great dream and I sure wish that they would save my aging ass. I'd love to live in a world where diamond is cheap or cheaper than glass. Orbital elevators, new materials.... But it does not look likely in the foreseeable future.

    2. Re:from an actual nanoscientest by danila · · Score: 1

      First, there was research done in 1970s-1980s (Sorry, can't give you the reference or details), which showed that most scientists/engineers are very bad at predicting the progress in their field of competence for more than 5-7 years.

      Second, there is an observation (not sure if it is supported by hard data) that we tend to overestimate the short-term progress and underestimate the long-term progress. Of course, this is not a fundamental law, but overall this hints that nanoassemblers might become reality much sooner than most people expect, possibly, as soon as in 2020-2030, especially if you take into account the possibilities of technological singularity and mutual acceleration of technologies such as computing, AI and nanotech.

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    3. Re:from an actual nanoscientest by Goldsmith · · Score: 1

      Sure, I agree. I think it's absolutely possible. The problem is that we're still working out the basics, and we can't ASSUME that it will just all come together. The experimental side of this will always lag the theoretical side, but we can't let the theory go too far without some sort of verification. We've already had it happen where a theory (molecular computing) went too far too fast, and led many people astray, only to be shown to not exist experimentally in the way the theorists predicted (see last October's Science for a summary). Again, that doesn't mean it can't be done, it just means you have to pay attention to the physical reality, and not get too excited by predictions.

    4. Re:from an actual nanoscientest by danila · · Score: 1

      I know I will be scorned by you for this, but I will say it anyway. :) I am not a nanoscientist. Even more (or less), I am not a physicist. So although I am still excited by some of the real physical problems that we face, this excitement is limited by my inability to fully comprehend them. So personally (sorry about that) I prefer speculations (hopefully with some basis in reality) about transhuman and posthuman possibilities of advanced nanotech, AI and hypercomputers to analysis of real (by that I mean things more advanced than the level of this particular dicussion covered in the article) technical or scientific issues (not to say I don't like to read a scientific paper on these topics occasionally).

      Another thing is that being relatively young and more optimistic about the speed of progress than you are, I already (to a large extent) feel like an immortal being (however strange that might sound to most people). For this reason I do not worry too much about immediate developments (although I still care about it), knowing that in 10-20-30 years things will somehow work out (yeah, I do realise people like you are responsible for this somehow).

      Speaking about predictions, while they might look silly to a physicist, they are extremely useful to politicians, businessmen and the public at large. While we might not know the exact schedule of nanotech development, we know enough about it to be able to give some estimates. There can be many techniques, although few with proved reliability, to be used for such forecasting. You can read some of my ideas about planning and the need for it in my small essay Planning for the Future. BTW, overoptimistic predictions are nothing good, I agree here. The question is how to make realistic ones...

      --
      Future Wiki -- If you don't think about the future, you cannot have one.
    5. Re:from an actual nanoscientest by eyegrep · · Score: 1
      Everything seems most difficult when you cant see the practical way forward. Moores law is consistently seen as coming to an end, but always comes up for another gasp. How do you create strained nano-structures? I dont know, but someone will discover a way. Etc.

      You talk of impediment. How is creating a vision - a goal - an impediment? Smalley and many others entered the field inspired by Drexler! At a practical level, the assembler researchers get no direct funding from NNI. Furthermore, Drexler himself is the first to say applaud the experimentalists. Foresight hands out a theoretical and experimemtal prize every year.

      You make comments about scaling, vacuum, and thermal limits, as if they havent been thought through. Have you read Drexlers book Nanosystems ? (1992, basically his PhD thesis). He begins with a chapter on scaling of numerous physical parameter leading to highly conservative design assumption thereafter. He defines of the required hardness of the vacuum required. He works though assumptions relating to thermal activity. He describes expected stress and strain on structures. Etc. Everything is conservatively pinned down.

      I challenge you and other experimentalists to find holes in his published technical arguments.

    6. Re:from an actual nanoscientest by Goldsmith · · Score: 1

      The main reason I downplay the assembler idea is that I don't want nanotechnology to become the next space program. That is, I don't want to have big expectations put on us so quickly, that when we can't deliver, we're tossed aside.

      The reasons you're excited about the future are the same reasons I went into physics. I love science fiction, and I'd love to see all the cool things people think are possible. There is so much that nanotechnology can offer that is NOT assemblers, I want to see that stuff too.

      I have to say, I was very dissapointed when I started doing nanotech research and realized that no one was working on assemblers. After a little while it made sense. Drexler compares us to the atomic scientests of the 30's, where I would compare us to the solid state scientests of the 40's. We're still looking for our transistor, and even after we find it, it's going to take a while to turn it into something usefull.

      After reading your website, I see your points about directing research in usefull directions. The problem from an experimentalists point of view is that the most exciting and most profitable results often are a surprise (the laser, and the scanning probe microscope are good examples). What makes this exciting is the possibility of getting something absolutely unexpected and amazing.

      Another way of looking at it, is that we're not yet to the point in the technology tree that we can look at assemblers as a possibility. We still have to get through basic nanotech, and probably a good deal of genetics, to get there. Right now, no one knows how long it could take. It could be 10 years, but it could also be 200 (look how long fusion is taking).

      I don't have any problem with anything you say, except to imply that I'm old. After reading your website, I'm actually six months younger than you are!

  145. A: Different approaches. B: Ongoing development by Ungrounded+Lightning · · Score: 1

    Richard Feynman talked about nanotechnology way back in 1959--before "nanotechnology" was even a word.

    It kind of irks me that the person who coins a word gets more credit than a person who talked about the actual process--nearly thirty years prior.


    Feynman talked about working downward using bulk mechanical processes. (That's exactly what the semiconductor industry has been doing, by the way.) When you approach the molecular level the rules change drastically. As with crossing the sound barrier, you need to make some fundamental changes.

    Drexler took a different approach: START at the molecular/atomic level, working with molecular/atomic rules from the start. Biochem offers both a proof-of-principle (in the form of complex systems build from molecular machines) and bootstrapping tools for implementing your early designs.

    So Drexler's work was profoundly distinct from Feynman's conjecture.

    Also: Drexler followed through enough to inspire others to start both basic and applied research projects, and to form organizations for exchanging information and advancing the field (even if SOME of them are now taking Feynman's approach using mechanical scanning microscope technology).

    Just as Columbus vs. Lief Ericsson (or Pythagoras), it's the person whose work leads to ongoing development, rather that the one who first speculated correctly, who gets the credit.

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  146. not love, but good enough. by garyrich · · Score: 1

    Smalley says:

    "You still do not appear to understand the impact of my short piece in Scientific American. Much like you can't make a boy and a girl fall in love with each other simply by pushing them together, you cannot make precise chemistry occur as desired between two molecular objects with simple mechanical motion along a few degrees of freedom in the assembler-fixed frame of reference."

    To strain the analogy - no, but you can probably get them to mate and that's good enough. A better analogy may have been that you can't take Feynman's parents and smash them together and get Richard Feynman. That would be truer, though if you did it enough times you would probably come pretty close. Drexler's ideas on mechanosynthesis assume a certain amount of waste and a certain amount of "close enough".

    --
    -- your Web browser is Ronald Reagan
  147. One-arm assembler is a strawman. by Ungrounded+Lightning · · Score: 1

    The idea of a nanobot twisting a pi-bond here and snapping a sigma-bond there seems quite ludicrous; where such reactions occcur in the real world it is because of the properties of the exact molecules involved and is reaction-specific.

    And the same applies to macrotechnology. Look at an actual factory: It does NOT consist of a single robot arm with a single tool-tip. You have hundreds of specialized machines and jigs. (Just for starters you do NOT handle molten steel with a pair of pliers.)

    The concept of an "assembler" as a single robot arm expected to build ANY molecular structure by positioning its component atoms, one at a time, regardless of the type of atom, the type of bond to be made, or the electromechanical environment of the partially-assembled product is a strawman. A real system will use multiple specialized jigs and tools - perhaps creating some on-the-fly - to apply force and fields in specialized situations - explicitly solving the "fat fingers" and "sticky fingers" problem Smalley claims is intractable.

    Yes, there may be some configurations of atoms that are very hard, or even impossible, to construct. But given the ability to build nanoscopic jigs and specialized tools to apply mechaincal, electrical, and magnetic forces, tuned electromagnetic energy, and kinetic energy (in extreme amounts if necessary), a nanofactory should be able to make essentially everything that can be made any OTHER way, including duplicates or modified versions of everything we see around us now.

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  148. As Usual The Morons Rule by Master+of+Transhuman · · Score: 1

    Most of the posters write comments about social and environmental contexts that nanotech will make obsolete - something Drexler warned against in his first book.

    Smalley's comments are on a par with the IBM guy who said back in the fifties or early sixties that the world would only need, what was it, X (where X was an extremely small value) computers.

    --
    Richard Steven Hack - This sig is TOO GODDAMN SHORT TO DO ANYTHING USEFUL WITH! MORONS!
  149. Seems like snake oil to me by Evil+Pete · · Score: 1

    Where is the energy coming to extract the atoms, move them create the chemical bonds move the nanites etc etc. I think we will get nanotech but a lot of the nanotech postulated just seems like modern day alchemy ... just wishing for a magic wand. Reality check required I think. And don't forget the amount of information required to position all those atoms to duplicate the Ferrari, where is it stored, what about inter-nanite co-ordination and communication ... argg. More likely there will be nano facilities (as in 'factories') that will make components for robot assembly, but just a bunch of nanites building stuff forget it ... look at bacteria for a model and see what they can and cannot do, they are highly sophisticated nano machines.

    --
    Bitter and proud of it.
  150. My summary by mec · · Score: 3, Funny

    I read Engines of Creation, got all fired up, went back to undergraduate school for a second undergraduate degree in chemistry, and really loved quantum mechanics. But organic chemistry opened up a serious can of kick-butt on me!

    So I can read the debate but damned if I can make an intelligent contribution to it. Maybe I can translate it down a little:

    Drexler: Yo, machine-phase chemistry is the bomb. We can put atoms wherever we want and make anything we want!

    Smalley: No you can't, dork. Atoms are not little balls and bonds are *really* not little sticks. You can't build molecules like tinkertoys.

    Drexler: Enzymes do it in nature, therefore it's possible.

    Smalley: Well, if you wanna make more better enzymes, great, but enzymes only work in water-based living cells and it's kinda hard to grow a cell phone from organic components.

    Drexler: My machine-phase chemistry will be to living enzymes as a metal airplane is to a bird.

    Smalley: Whatever. Go do your "machine-phase chemistry" and come back when you've actually built something. Hint: I think it's gonna take you 200 years.

    I think Smalley is wrong when he says that it's by nature impossible. And I think Drexler is wrong when he says nature has already provided an existence proof. I think we should get started on those 200 years of work and see what we can do!

    1. Re:My summary by maken · · Score: 1

      You missed the part in Drexlers conclusion:

      Drexler:This is going to take a very long time so if everyone can pitch in maybe we can get it done quicker!

    2. Re:My summary by Genda · · Score: 1

      Personally, I don't know why this was rated funny when in fact it is more insightful. Current biology does in fact demonstrate that nanotech is possible and plausible... Of course the first nanotech will happen in a suspension, we need the support provided by a solvent to bring materials into the sphere of assembly. That's perfectly fine, especially since most of the things we are going to want to do with nanotech right off the bat, involve changing, fixing, improving, and extending the warranty life of biological systems in vivo.

      It's likely that some of the first nanotech will require using biological entities (bacterium, phages, and or virii), to do the assembly and production of some part or all of the more interesting first machines (If you've never seen the motor that drives a bateria's flagellum, it's indeed a work of art.)

      Once we have machines capable of actually constructing smaller structures, we can work our way down the ladder of scale. Right here on /., a while back there was a report of a machine that uses a holographic lens to produce many finges of light with the additional property of being able to grab, move, and rotate microscopi objects. Can you think of a better tool to begin working on manipulating the materials required to build the first true assemblers.

      The problem here is that one man (Dr. Drexler) see's that there's this possibility, and that the exponentially accelerating rate of human knowledge is almost certain to place that thing, that possibility squarely in reach much sooner than anybody suspects. While another man looking at the past, makes a judgement call from his experience. This is not bad, it's just uninformed. We can now build custom virii from genetic sequences. We can move atoms. We can produce buckytube semiconductors and a whole new class of high temperature superconductors is barely a hop skip and jump away. The next ten years promises to give us tools capable of seeing back to the moment the universe became transparent, and surely the ability to build nanomachines is closer than anybody can guess.

      This is one of the reasons that we need to come up with a new class of technologist, somebody who is versed in let's say 10 or 20 disciplines, and can draw from diverse pools of thinking... cross polinating and combining fields of endeavor. Our own biochemistry has demonstrated that fat and sticky fingers are not a limitation. We're still deaf and blind when is comes to interaction at the atomioc level. That won't be the case forever. Only a fool bet's against human ingenuity.

      By the way... I've been a member of Foresight... I know the size of the brains working on this... don't for a minute believe that anything is impossible given enough time, talent, and funding.

  151. Nanotechnology timeline by randall_burns · · Score: 3, Informative

    A while back, Sean Morgan did the most interesting work I've seen on a timeline and prerequisites for Nanotechnology. At present, odds are that we'll see an assember sometime around 2022.

  152. How could it not be possible? by d3am0n · · Score: 1

    Every organism on earth does it at a cellular level, so what knob would think that we couldn't just replicate the machinery and do it ourselves? Obviously it's physically possible or none of us would be alive right now

    1. Re:How could it not be possible? by ciphertext · · Score: 1

      Disclaimer: I am not a chemist nor a biologist.

      We are not inorganic systems. We are very much organic. We are assembled buy the process of cellular replication and organization. We rely on enymes and ribosomes to correctly "manufacture" our cells. Those enzymes and ribosomes only "work" in water. I am not certain that there exists any other form of enzymes other than those that function in water. At least, none that are as useful. Unfortunately, water-based chemistry limits us in what we are capable of "assembling" to pretty much the organics. That is why humans are composed of carbon based components, and not made with a steel outerskin. If we were able able to manufacture inorganic components, then we would probably be made of something sturdier than flesh and bone. We might not even require the use of oxygen in our energy production. We as organisms, were created by components that were readily available in the environment. Our development as an organism is limited by the restrictions that the building materials presented to us. Just as a builder is limited to what they can build with concrete and steel, we are limited in how we can develop by the organics.

      If we travel down the path of nanomachine creation that mimics how we as humans (and all of biologic life) developed, we will be limited to the same constructs that nature was limited to.

      --
      To know is to have knowledge....to understand is to be enlightened.
  153. My Nano Assembler design by GodSpiral · · Score: 2, Interesting

    Apparently my design for a molecular assembler is deemed impossible for the sticky or fat finger aspect, but I need help understanding why this is impossible. I think I can circumvent that problem.

    Anyways here's the design. It is simple and achievable. It is not conducive to building/replicating itself easily though.

    The core is an STM microscope-like device, with many parralel tips each working on its own square millimeter (or smaller) area. Needle Tips or fingers doped with the next mollecule (properly oriented) to be inserted move along a conveyor belt where each are inserted into one of the parallel heads, the head then sticks the molecule in place, then the needle is sucked out, and sent to be refilled.

    I don't really have a process for making mollecules, and placing them in the proper orientation on a needle.
    The one good thing about this design, is that there probably exists a needle material than can react "properly" with any given mollecule, such that it can 1) capture it, and 2) release it. (One method of releasing could just be to jab the needle quickly forward, flinging the package into place).

    There's one problem with Drexler's universal assembler theory, with little publicity, that is only partially solved by my design. There is not an infinite number of universal assemblers created instantly, and as a secondary problem, programming them to work and move around cooperatively is not easy, and increases their required size if only because of the massive cpu they need to operate with.

    The Other issue only partially addressed is speed. If everything is built using 3d tetris-like merging of 10nm building blocks (mollecules), then finishing a square milimeter takes 10B blocks. A quadrillion blocks makes a cubic milimeter of something. Even at 1 billion blocks per second, it takes 11.5 days to make 1 milimeter thick object. The billion blocks per second seems outrageously high to reach, but another way to increase throughput (but increase congestion of feeder needles) is to have denser parallel heads. If each head works on a square micrometer area, then building a cubic micrometer object takes 1 million 10nm blocks. At (only) 100K blocks per second, a 1mm thick object takes 10,000 secs = 2.77 hours

    There's one other big problem. Like building a house of cards on an uneven surface, mollecules won't necessarily maintain a desired orientation without simultaneously placing adjoining molecules to couterbalance them. Seems like there would be a solution to this, with all the arms in such close proximity, but it would also slow down the process.

  154. Re:I never understood how it was supposed to work. by Anonymous Coward · · Score: 0

    > I do believe we will be able to build objects, I just don't think little robots will be doing it.
    > I think we it will be more like creating and destroying matter by combining/absorbing
    > energies in organized fasions.

    So, you're basically saying that you find a Star Trek transporter to be more plausible than molecular assemblers? Okaaaaay.....

  155. Recommended book by bloodSausage · · Score: 2, Informative

    Author: Atkinson, William Illsey
    Title: Nanocosm: nanotechnology and the big changes coming from the inconceivably small

    Summary: Atkinson is a technology reporter who surveyed the nanotech field (actually talked to researchers), and from his perspective, Drexler's assembler is not feasible, but he gives lots of other examples of nanotech now in labs around the world.

    If you think Drexler is right, reading this book might change your mind.

    1. Re:Recommended book by bradbury · · Score: 1

      Note the statement: "is a technology reporter" and "from his perspective". Since when has a reporter ever been able to judge the scientific or engineering feasibility of something? Then when you have a reporter talking to scientists one has to ask whether or not they are *really* informed about the topic. In this case one has to ask whether or not the scientists have read Drexler's papers as well as his PhD thesis (recast as Nanosystems)? If they have not done that they cannot be considered informed sources and so their opinions may be useful but hardly authoritative. Its like going to the leading hitter in baseball and asking him for advice on how to throw an great pass in football.

      Drexler, Merkle and Freitas (as well as some scientists at Caltech like Goddard and the nanotech group at NASA Ames) are the authorities in this area. Anything anybody else says should be subjected to intense scrutiny with a raised eyebrow.

      Robert

    2. Re:Recommended book by eyegrep · · Score: 1

      Actually, Atkinson has backed down from his hard-line assmblers-are-impossible position. He was challenged to a debate with Chris Phoenix of CRN.org, where he was challenged on numerous factual errors, and eventually softened his position and entered into a useful dialog. See http://nanotech-now.com/Atkinson-Phoenix-Nanotech- Debate.htm.

    3. Re:Recommended book by Anonymous Coward · · Score: 0

      > See http://nanotech-now.com/Atkinson-Phoenix-Nanotech- Debate.htm.

      After reading this exchange, I think we can safely discount anything Atkinson has to say. The guy is a clown.

  156. Who to believe? by BigBadBri · · Score: 4, Insightful
    I'll take the Nobel prize winning chemist, with a track record of experimentation and success, over the self-aggrandising bullshit artist who has produced nothing but dead trees and wild ideas for the last couple of decades.

    But that's just my point of view - I dislike Drexler's constant reference to Feynman, his total lack of any experimental pedigree, and his unwillingness to take on board the views of those who actually know a bit about what he spouts off about, because they have tried it.

    Reading the article, it seems that Drexler in his second letter ignores the fact that he is contradicting what he says in his first letter, because the mechanisms proposed in the second would inevitably require the very same 'Smalley fingers' that he derides in his first polemic.

    Drexler is just pissed that someone with credibility and experience has pointed out the holes in his arguments, and cast doubt on his percieved achievements (which are roughly on a par with other Sci-Fi authors, IMHO).

    Leave it to guys like Smalley - we'll end up with nanotechnology that works - maybe not the grand self-replicators in the first iteration, but at least we'll have technology rather than the PR puff and self-publicity that characterises Drexler's current output.

    Sorry for the rant, but Drexler really, really pisses me off.

    --
    oh brave new world, that has such people in it!
  157. we already have "molecular assemblers" by penguin7of9 · · Score: 1

    They are called "enzymes". They are built from stuff, mostly carbon, hydrogen, oxygen, and nitrogen, that is ideally suited to doing this sort of thing. And they have been optimized over a billion years by "genetic algorithms" for doing this thing. It seems pretty doubtful that one can design a better toolkit for "molecular assemblers" than what molecular biology already gives us. We'll be able to build different tools out of that toolkit, but nothing of the sort as described by Drexler or in Stephenson's novels.

  158. For now, Smalley is right. by jasper747 · · Score: 3, Informative

    From the exchange, Drexler gives the impression that matter at the atomic scale behaves in the same way as matter on the macroscopic scale that we live in.

    Physicists and chemists would know that this assumption is false. The Dalton theory of atoms as billiard balls has been refuted a long time ago.

    How is a mechanical manipulator going to "grab" another atom? These manipulators are also at the atomic scale! Duh.

    Today near the bottom of the http://www.foresight.org/ website, it shows a unrealistic graphic of one of Drexler's proposed nanofactories. There are what appears to be spherical atoms being manipulated by machinery. -- It fails to accurately show that the machinery is no more solid than the lego atoms that the machinery is manipulating. (Unless maybe the machinery material is made of some sort of selectively reactive/nonreactive, subatomic material)

    When I see pictures & notions like that being bandied about and sold to the public, I get the same feeling when people push Jules Verne's voyage to the moon as science rather than science fiction. -- Baloney.

    Right now Smalley wins. He's a doer, an implementer.

    Drexler may get the last laugh in the far future, but some real science must appear first to make science fiction a reality.

    The really hard stuff is in the implementation. The implementers deserver the real credit.

  159. Keep them together (keys and docs). by djupedal · · Score: 1

    That works, until you have several cars, trucks, motorcycles, boats and airplanes :)

    1. Re:Keep them together (keys and docs). by wideBlueSkies · · Score: 1

      And several sets of keys right? ;)

      --
      Huh?
    2. Re:Keep them together (keys and docs). by scilsic · · Score: 1

      Ferrari Inc. has you DNA profile on file, and you're concerned with carrying around documents?
      How about retina, fingerprint and passwords?

      Better yet.. make sure the car requires this to start.
      Seen Tomorrow Never Dies? Like the alarm system? Build it ;-)

  160. Second Life by Saeger · · Score: 1
    Speaking of realestate and the game SecondLife, that's one of the main reasons I didn't end up paying for a subscription after my 7-day trial was up: Almost all of the good "land" was already claimed and/or too expensive. The frontier seemed to be closed.

    In a virtual world there IS NO SCARCITY, so why immitate it? Because it's what people are used to? There's room for multiple planes of existence along side the common "consensus" reality.

    Anyway, back to Earth (sortof): In a nanotech future, there's still the fundamental scarcity of the following:

    • Time
    • Space
    • Energy
    • Matter
    • Intelligence (limited by the above)

    However, the sun is abundant free energy, and there's more than enough living space on Earth (underground, and on & under the oceans), in outerspace (Mars, orbitals, rings, etc.), and in innerspace (the transhuman "matrix").

    The other reasons I didn't keep playing SL was the crappy physics (esp. most vehicles), low graphics detail compared to what I'm used to, and no linux client (unlike "A Tale in the Desert", which is most similar to Secondlife).

    --

    --
    Power to the Peaceful
    1. Re:Second Life by jafuser · · Score: 1

      The word "pioneer" in my SL signature was not a casually-chosen word. SL has only been out for six months, and may not be a comfortable place for people who can't stand rough edges. But I guarantee you, it is evolving quickly, and the people behind it are very bright and the developers have true geek talent and spirit.

      Land is expanded as a world-wide grid, one server (called a "sim") at a time. Each "sim" is a 256m x 256m plot of land. The system is very modular; you can move seamlessly between sims.

      There is still a lot of land available on the "PG" sim, but most people prefer the "M" (mature) sims since they have the freedom to put adult content on their property (yes even nekkid pics).

      A linux client is coming soon. They just released the first Mac alpha client a day or two ago.

      To be on topic, a lot of the concepts people are bringing up about Intellecutal Property rights of physical objects are addressed in SL (though they are easy to enforce in a virutal world).

      There is an extensive system to grant permissions to modify, copy, sell or give away objects. These permissions are always granted to the original creator, but the creator can then restrict these permissions on copies given to other people. I'm currently lobbying the developers for a "allow free use if derivative use is free" style permission.

      In that regard, it would be interesting to see how a GPL-like license would work in a nano-builder type of world.

      --
      Please consider making an automatic monthly recurring donation to the EFF
  161. Smalley right, but great stuff still out there by Dan+Weaver · · Score: 1

    I'm a PhD student in biophysics at the University of Michigan. Reading Engines of Creation and Nanosystems a couple of years ago (when I was an undergraduate in physics) inspired me to do what I am doing today. Since then I have learnt a bit about biochemistry and enzymology and exactly how we currently think things work in the protein and RNA nanomachinery that you and I are built out of. Based on what I have learnt, I don't think that Drexler's proposals are feasible. In my opinion Smalley is all the way right and Drexler is all the way wrong in this exchange. Smalley makes a very accurate explanation of why Drexler is wrong, and Drexler's second response sadly goes into my 'hot air and hand-waving' file.

    Ask me again if Slashdot is still around in fifty years. By that time, perhaps we will have made some progress on the folding problem and the design problem and the aggregation problem in protein manufacture. Maybe we will have long term simulations (get to work, supercomputer aficionados!) and we will be making awesome custom proteins and doing great things evolution never thought of. Perhaps then we will be able to do some kind of positional control magic that will allow us to make Drexler's end-of-Nanosystems bootstrap from proteins, lipids, and RNA to diamondoid materials. Until that time...well, if Richard Smalley, one of the world's foremost carbon chemists, says it will never happen, and it is his word against non-Nobel-Prize-winning-carbon-chemist K. Eric Drexler's, I will go with Smalley's opinions. (Three years ago I would be appalled at myself for writing all this!)

    I will always appreciate Drexler (and Ion Storm and Neal Stephenson) for getting me fired up about investigating what goes on at the nanoscale. Without those wild claims I might not be having the fun I'm having today.

    In closing: cheer up, nanofans! You and every other living thing on earth are glorious nanomechanical devices, well worth detailed study and sincere appreciation. In the future we shall hopefully be able to improve upon Nature's wonderful handiwork. For the time being take comfort in the sublime fact that millions of nanomachines all must strive together to do something as seemingly effortless as attaching the period that will now close my post.

  162. Fair Use! by Anonymous Coward · · Score: 0

    I need the copy for when I crash the first one!

    ooops

    Better copy myself too. :0)

  163. electromag vacuum process by Anonymous Coward · · Score: 0

    i see nanotech becoming real and accessible at the same time as quantum computers become useful. the same magnetic wells can be used with varying degrees of fineness to manipulate individual atoms and components of atoms into more complex objects. the lack of actual contact with the suspended molecules removes the sticky, butter finger aspect and resembles the blowers in newspaper plants that incorporate the flyers into the paper. molecules can be assembled in multiple chambers and moved to an assembly station for final inclusion in a product. interesting to think that the fusion reactors of the past (tokamak, with their pool of plasma to draw from)) will be the basis of nanoassemblers in the future....

  164. Replicate clothes from what? You need the basic by Anonymous Coward · · Score: 0

    building blocks to "Replicate" your free stuff.

    Besides... who wants to spend time "Assembling"
    stuff all the time.

    Prolly be much cheaper to go to a "Replicator" outlet and put in an order for what you want and
    pick it up before you leave.
    Let the pros design the crap and the outlets
    wharehouse the raw materials. I just want a home
    replicator for basics.

    In the meantime I suggest you get a bit more schooling. Your logic is flawed.

    1. Re:Replicate clothes from what? You need the basic by gnovos · · Score: 1

      Replicate it from dirt and trash. All the basic building blocks you ever wanted right under your toes.

      --
      "Your superior intellect is no match for our puny weapons!"
  165. Self-replicating factory: a cow by Latent+Heat · · Score: 1
    If you want to see a self-replicating factory-like thing, we have a lot of them here in Wisconsin: cows. A cow will eat grass and produce milk, and it will (with the proper mating) produce a calf which will grow up to eat more grass and produce more milk.

    I mean what could be simpler, and what could produce more wealth than owning livestock, only the things need shots from the vet so they don't die from disease, and the calving process can get kind of hairy, and these things produce piles of poop which needs to be shoveled off to some place, and you kind of get the picture. And then everyone's neighbor has a stable of these things so milk gets cheap and it is really hard to make a living at it, but I guess milk is cheap and abundant to consumers.

    What I want to know is that when we get self-replicating machines, how will they differ from livestock, especially with regard to the waste-management and keeping them free of disease ends?

  166. Clarkes third law by Anonymous Coward · · Score: 1, Insightful

    "When an distinguished but elderly scientist states that something is possible, he is almost certainly right. When he says something is impossible, he is very probably wrong." - Arthur C. Clarke

    1. Re:Clarkes third law by DingoTango · · Score: 1
      That is actually Clarke's First Law. His third is this:
      "Any sufficiently advanced technology is indistinguishable from magic."
  167. Well, NGEN (nanogen) got a patent today. by joejoejoejoe · · Score: 1

    http://web.archive.org/web/20020802085307/www.colu mbusgaming.com/cgi-bin/ikonboard.cgi

    [snip]

    Nanogen Issued Key Nanotechnology Patent
    Wednesday December 3, 8:02 am ET
    Newly Issued Patent Broadens Proprietary Position in Nanomanufacturing and Nanotechnology

    SAN DIEGO, Dec. 3 /PRNewswire-FirstCall/ -- Nanogen, Inc. (Nasdaq: NGEN - News) today announced that it has been issued U.S. Patent No. 6,652,808, "Methods for the Electronic Assembly and Fabrication of Devices," ("the '808 patent") by the U.S. Patent and Trademark Office. This patent is the parent of a series of pending patent applications that significantly broaden Nanogen's proprietary position in the nanotechnology and nanomanufacturing areas. The Company has now been issued nine patents during 2003, bringing the total number of patents issued in the U.S. to 56.
    [/snip]

    Makes me wonder if both of these guys are missing the boat, b/c to my lamen eyes it appears that nanogen just patented something like what they are talking about...

    -disclosure- I own nanogen stock, and have for more than 2 years.

    -Joejoejoejoe

    --
    Silly Rabbit: tricks are for kids.
  168. Drexler's won't be an optimist for 7 more years. by jbum · · Score: 1
    "These developments [molecular assemblers and nanomachines] will sweep the world within
    ten to fifty years - that is, within the expected lifetimes of ourselves or our families.
    "


    -- K. Eric Drexler, "Engines of Creation", 1985



    When I read these words in 1986, I only remembered the "10" and forgot the "50". This is the problem with books containing predictions.

    Okay Drexler: 18 years are up. When we hit 25 you will officially be branded an "over-optimist". Then you'll have 25 more years before you're officially an "insane crank".

  169. It will happen. by supabeast! · · Score: 2

    Plenty of people will say that molecular/atomic assemblers are impossible right up until the big breakthrough that makes it possible. That's how science works. People said that all sorts of computing stuff was impossible because vacuum tubes were too big, and then, all of a sudden, somebody figured out how to make transistors. All kinds of important stuff was impossible to figure out because the aether complicated it all and could not be measured, and then Einstein pointed out that it did not matter because the aether did not exist. Right now people are insisting that we will hit computing speed limits due to the limits of CMOS-but does anyone really think that there won't be a replacement?

    Anything can happen with science. Magic is just what science cannot explain, because we have not figured out how to do it yet. But eventually, given enough time and resources, anything is possible.

  170. They should put their money where their mouths are by Wocko · · Score: 1

    I think a Long Bet is the answer.

  171. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  172. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  173. Re:I never understood how it was supposed to work. by Anonymous Coward · · Score: 0

    Your candor is refreshing, sir!

    Have another glass, on the house! :)

  174. Are Molecular Assemblers Possible? by lord_nightrose · · Score: 0

    In a word, no. In another word, yes.
    ... is hilarity ensuing yet?

    --
    This is not part of my post. It's my signature. I bet you're disappointed.
  175. Re:I never understood how it was supposed to work. by Anonymous Coward · · Score: 0

    Let's get a string of molecules to encode information, and then get a structure to translate it into actions, and then get robots to communicate via chemical concentrations..... .... ...Wait, doesn't this just describe LIFE?
    So we can build artificial life, and get it to create artificial molecules from tailored amino acids. Cool.
    This should not be underestimated, but we'll do it by genetic engineering, not atom by atom.

    What are the chances of assembling things atom by atom, as Drexler "Look kids, nanotechnology is possible, according to math proofs I lack space to show you" keeps insisting it is?

    BTW, that was his response when there was a big Scientific American article why molecular assemblers are impossible. (that, and his response also included "I'm sure we'll find a solution to some of the other problems REAL SOON NOW")

  176. Common misconceptions about our nanotech future by danila · · Score: 2, Interesting

    Most people do not really understand the potential impact of mature nanotechnologies. And it's easy to see why - even Drexler's book Unbounding the Future: The Nanotechnology Revolution gives some really ridiculous examples (may be to make it simplier to understand). Here are my responses to two of particularly misleading comments in this thread.

    2BorgDrone :

    However, if molecular assemblers ever become mainstream I'd rather design my own car and let it assemble that. If everyone is driving a Ferrari I'd rather have something different.
    When molecular assemblers become mainstream, having a car would be rather pointless. First, there are unlikely to be any streets where you can impress chicks, since everyone would be able to live wherever on Earth they like. Second, there probably won?t be any roads, since you don?t need to transport goods (they can be manufactured from CO2 on the spot) and it?s easier to fly people from A to B. Third, designed cars would be as old-fashioned as horse carriages now ? smart completely transformable people-movers would be all the rage. And forth, you will be able to drive any kind of car in your personal virtual reality simulation, so you don?t need to actually design the car (just program how it should behave) and the issue of IP would be moot.

    2jchoyt :
    Money will still have value. Someone has to create and/or design food, clothing, medicine, entertainment, etc.
    Strong AIs will be able to create and or/design everything, including these things you describe. Furthermore, people will not need food, because it will be easier to just get energy from the environment without any conscious actions like eating from your side. Clothing is likely to be designed for the sake of it. Most couturiers are not in this business for money, they do it because they like it, and when all fabrics and basic production operations will become free, as well as everything they need personally, they are unlikely to charge you anything for their latest fashionable clothes. Medicine will not be used, because our bodies will be redesigned to include a smart AI-based immune system, capable of fixing most problems, except, may be, for being in the epicenter of the thermonuclear explosion. So most things you mention will not be needed and those that still will be needed, will be done by professional volunteers for free.

    --
    Future Wiki -- If you don't think about the future, you cannot have one.
  177. Aspects vs. Aproximations by MarkusQ · · Score: 1

    No, neither chemistry nor physics are approximations, the words refer to aspects of reality

    The only way in which this makes sense is if you interpret "aspects" to be a near synonym for "aproximation" (something like "situationaly valid aproximation"). But that's a far cry from saying they "are reality," which I gather is your intent.

    That's just nuts, especially with regard to chemistry.

    • The vast majority of the universe by volume is in the intergalactic voids, where atoms are so few and relative velocities are so high that chemistry as we presently know it doesn't apply. Maybe someday we'll have a relativistic chemistry of ultra-hard vacuum, but it isn't what we know as chemistry today.
    • The vast majority of the universe by mass isn't even normal matter.
    • The vast majority of normal matter in the universe exists in plasma where chemistry as we know it can't take place (all the orbitals are unoccupied) or in deginerate matter where there aren't any orbitals possible.
    • The vast majority of what's left, while potentially chemically reactive, never has a chance to do much beyond meeting another likeminded hydrogen atom for a few eons of H2 action.
    Chemistry is an aproximation that gives a very useful description of some aspects of reality under a narrow range of conditions that happen to be interesting to us.

    It is not "Reality," any more than biology, economics or cartography are "Reality."

    -- MarkusQ

  178. Assemblers by danila · · Score: 1

    I think it is understandable why no one is building assmblers now, but we can expect some assmblers in the near future. Not nanoassemblers, of course... The problem is that we currently don't have computing and programming (AI) capability to build even a simple universal robot, much less an assmbler, much less on a nanoscale. We can definitely see today how fast will robotics develop. There are many good projects on various important aspects of robotics, there are first consumer robots, there are first relatively autonomous robots, we are making a good deal of progress in actuators, energy storage, etc. Without doing a good deal of analysis, I can give a very rough estimate that 2010s will end in a robotic boom - a visible stage of exponential growth we are already experiencing (like Internet in late 1990s). At that stage it will be possible to design and somewhere around 2015 build a macroassembler - a robot (robotic plant) capable of turning relatively simple parts into anything that can be built out of them (including more such robots) given right instructions. Ordinary people will see it as, for example, robots doing more construction work and maintenance. At that stage nanotechnology might progress by approximately 1-2 orders of magnitude. This would allow to gradually shrink our universal assemblers and by 2020-2030 they might become nano-scale.

    So I surely agree that building a nanoassembler is out of our reach now (although some theoretical work is still in order), but assemblers are much closer. The theory of building assemblers is related to cellular biology and correlates nicely with our gradual progress in that area and in scanning/imaging technology.

    The ideas above, are of course, just speculation, and is not based on hard data, but this is an example of what kind of planning is, in my opinion, necessary.

    As for your age, I happily admit my error, but now I am surprised by your "deathist" attitude. Why shouldn't you to live to see the assemblers even if that will take 70-100 years? Surely some life extension technologies will arrive much earlier.

    --
    Future Wiki -- If you don't think about the future, you cannot have one.
    1. Re:Assemblers by Goldsmith · · Score: 1

      Upon reflection, my "deathist" attitude, as you put it, does seem pretty depressing. I think it comes from a combination of things.

      I started off in science in the fusion industry and the history there is pretty oppressive. That, in addition to the slow day to day progress is probably what causes it. It's hard to think of asssemblers when today I have to re-wire some basic electronics. It seems like everyone is talking about assemblers but the people who are working on nanotechnology.

      This whole discussion has made me go back and look at what got me into nanotechnology. It was actually Drexler's book. Most of what Drexler says about nanoelectronics would lead people to believe that what I'm doing is impossible, and that was only ten years ago.

      Maybe I just needed to be reminded why I started doing this again (thanks), but I think I agree with you now. Who knows what will happen even 10 years from now, let alone 70 to 100.

      I still disagree with the methods Drexler proposes, but that's a different issue.