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Scientists Say Nerves Use Sound, Not Electricity

gazzarda writes "The CBC is reporting that a team of Danish scientists are claiming that nerve impulses are transmitted by sound and not electricity. 'The common view that nerves transmit impulses through electricity is wrong and that they really transmit sound, according to a team of Danish scientists. The Copenhagen University researchers argue that biology and medical textbooks that say nerves relay electrical impulses from the brain to the rest of the body are incorrect.'"

382 comments

  1. So when a tazer hits you by Anonymous Coward · · Score: 5, Funny

    ...its really the sound of the tazer that is making your muscles contract in all kinds of ways and you losing motor control, not the hundreds of thousands of volts coursing through your body.

    Wow... who would of guessed it!

    einstein
    http://anarchy-tv.com/

    1. Re:So when a tazer hits you by Anonymous Coward · · Score: 5, Funny

      There is only one real way to test this: put your head in a large bell and have someone ring it as loud as they can. If you lose all muscle control and are confused for a minute or so afterwards it would then prove that it is sound that controls nerves. Otherwise I suggest that we put a researcher in a specially made chair that will deliver high current directly through an electrode placed on the top of the head (and another somewhere else such as the wrists). If the researcher loses all muscle control then it also confirms that electricity controls nerves.

    2. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      Better yet: gather the researcher that thinks nerves use sound. Place electrodes on their intestines and place them in a public place in front of their peers (so the electrodes cant be seen of course). If he loses all muscle control, then you know his theory stinks.

      (get it? hehe)

    3. Re:So when a tazer hits you by hometoast · · Score: 3, Insightful

      I'll send you a jump to conclusions mat.

      It _could_ be that the electricity is exciting the nerves and, in turn, they are sending signals(by sound)...causing loss of motor control.

    4. Re:So when a tazer hits you by kestasjk · · Score: 4, Informative

      Current courses through your body, not volts.

      --
      // MD_Update(&m,buf,j);
    5. Re:So when a tazer hits you by LanceUppercut · · Score: 5, Insightful

      You need to take "Logic 101" classes. Just because muscles react to electricity (and body transmits electricity) does not prove in any way that it is necessarily electricity that is used by body to control muscles. In the same way one can conclude that just becuase body reacts to bullets means that it uses bullets internally, which is nonsense.

    6. Re:So when a tazer hits you by cp.tar · · Score: 4, Insightful

      There is only one real way to test this: put your head in a large bell and have someone ring it as loud as they can. If you lose all muscle control and are confused for a minute or so afterwards it would then prove that it is sound that controls nerves.

      That wouldn't prove sound controls nerves, for it is quite common knowledge that doing something like that would upset your middle ear, so you'd lose balance and become nauseous just because of that.

      --
      Ignore this signature. By order.
    7. Re:So when a tazer hits you by Instine · · Score: 1

      Volts don't course through anything. You want to mock the physics, learn it first.

      --
      Because you can - or because you should?
    8. Re:So when a tazer hits you by chris_sawtell · · Score: 4, Insightful

      The current bunch of moderators must have a horribly attenuated sense of humour. This is the first slashdot post for months and months that actually made made me fully appreciate the meaning of 'LOL', because I did! Yet it gets scored +5 'Interesting', while hordes of pathetic little jibes get +5 funny. I just don't get what makes you lot tick.

    9. Re:So when a tazer hits you by Antique+Geekmeister · · Score: 4, Insightful

      And electro-shock, EEG's, retinal implants, and the old squid cell experiments where you stick electrodes in a squid neuron and measure its behavior are all based on a wrong theory, because the idiot who wrote The Fine Article can't figure out where the heat went from conduction of electricity in living matter? It's sitting inside a living organism with lots of *other* thermal processes going on: the heat generation is easily lost in the thermal noise.

      I'll believe it when I see experimental evidence: but the article as presented is pretending that God makes timepieces himself because you found a watch in the desert. It's nonsense.

    10. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      I hate it when people write "would of" instead of "would have". Makes no sense.

    11. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      I just don't get what makes you lot tick.

      Why, sound, of course. Didn't you RTFA? :)

    12. Re:So when a tazer hits you by tenco · · Score: 1

      And what about EM waves?

    13. Re:So when a tazer hits you by AlHunt · · Score: 1
      It would explain the legendary "Brown Note":

      The story of the Brown Note, also known as the "Disco Dump," asserts the existence of a low frequency vibration which, when reproduced at sufficient volume, resonates with the depths of the human digestive tract to cause what medical personnel call "involuntary gastrointestinal motility." Put in less technical terms, the Brown Note reputedly precipitates a loss of sphincter control, giving rise to immediate defecation. Different versions of the myth place the frequency between 5 and 20 Hz, and recent variations claim that the effect has been produced at loud rock concerts.

      For more see here

      --
      1 in 4 Maine children in struggle with hunger.
    14. Re:So when a tazer hits you by Eggplant62 · · Score: 1

      Really, man. If you've ever had problems with carpal tunnel syndrome and have been in to be properly diagnosed, you've had some neurologist stick needles into your arms and hands to measure the electrical potential traveling along the nerves of the arm from shoulder to hand.

      I call bullshit, and I want whatever this group of Danish scientists are smoking. I'm betting trips to Amsterdam are de rigeur with these folks.

    15. Re:So when a tazer hits you by SpaghettiCoder · · Score: 1

      A saucepan is electrically conductive too, but that doesn't mean it applies an electrical current to cook your food.

    16. Re:So when a tazer hits you by b4upoo · · Score: 1

      I wouldn't poke fun at the research. At very low frequencies the differences between sound and an electrical impulse are obscure if not non existent. Some expensive metal detectors that operate at about 1.5K demonstrate that kind of signal output.

    17. Re:So when a tazer hits you by Kyle_Katarn-(ISF) · · Score: 1

      What? Didn't you see the episode of Mythbusters where they showed that wrong?

    18. Re:So when a tazer hits you by mikiN · · Score: 1

      Gives a whole different twist to the saying: When the shit hits the fan...

      --
      The Hacker's Guide To The Kernel: Don't panic()!
    19. Re:So when a tazer hits you by Tsaot · · Score: 1

      Just because muscles react to electricity (and body transmits electricity) does not prove in any way that it is necessarily electricity that is used by body to control muscles. Allow me to expand on his argument then. When you use front row tickets to the latest concert, you don't collapse to the floor twitching as the music starts. When you try to assault the lead singer because he's a complete jerk however, and security descends upon you with their tazer might, you do.
    20. Re:So when a tazer hits you by Yvan256 · · Score: 2, Insightful

      I hate it when people write "would of" instead of "would have". Makes no sense.
      Because they would have course be wrong in this case.
    21. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      Here's an even better elaboration. Just because a microphone "works by using sound", does not mean it won't flutter around when you put current through it.

    22. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      Kill them all and let god sort 'em tout!

    23. Re:So when a tazer hits you by Anonymous Coward · · Score: 1, Funny

      Dude, that would really piss off my symbiote. No thanks!

    24. Re:So when a tazer hits you by gitarman · · Score: 1

      Perhaps I misunderstand you, but I believe that at any frequency there is a vast difference between EM waves and Percussion waves For instance electricity even if in the frequency of sound produces no sound. OTOH sound waves, properly amplified, and of the proper frequency cannot power my radio (then again you can't even get a D.C. sound)!

    25. Re:So when a tazer hits you by Yubastard · · Score: 1

      lol long time since I heard that word jaja what symbiote you talking about? the ones from spiderman? or the ones from wetworks?

    26. Re:So when a tazer hits you by j00r0m4nc3r · · Score: 1

      This is not my field of expertise, but I would have thought the current from a Tazer travels over the outer surface of your skin, and not through your body. But Tazers obviously work, so my theory might not be accounting for something or other...

    27. Re:So when a tazer hits you by denttford · · Score: 3, Funny

      It is also well known to be a remedy for separating oneself from black gooey alien symbiotes.

      --

      Leben Sie jetzt die Fragen.
    28. Re:So when a tazer hits you by kestasjk · · Score: 1

      From a lazy electrons point of view; why travel through dry, dead, tough skin, when there is a nice, conductive solution of ions just beneath it?

      --
      // MD_Update(&m,buf,j);
    29. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      You fucking idiot, it's "would have guessed it" or "would've guessed it", not "would of guessed it". What the fuck would that mean anyway, you nitwit?

    30. Re:So when a tazer hits you by maxume · · Score: 1

      It takes the path of opportunity. That is, the body is messy, so an accurate model will be too, and as you note, they work, so some of it is going somewhere and doing something.

      --
      Nerd rage is the funniest rage.
    31. Re:So when a tazer hits you by ATMD · · Score: 2, Informative

      Sure you can get DC sound. It's called wind.

      --
      Nobody else has this sig.
    32. Re:So when a tazer hits you by cytg.net · · Score: 1

      right .. and if the force of the muscle contraction is proportinal to the electrical offset, does that tell us something ?
      the "if" part is pretty sure bet pr.101-logic.

    33. Re:So when a tazer hits you by ATMD · · Score: 1

      Thinking about it logically, you'd think that Coulombs course through things (and current is the rate at which they do this). So why does that sound wrong?

      --
      Nobody else has this sig.
    34. Re:So when a tazer hits you by Socguy · · Score: 1

      My understanding was that Tazers utilize massive dosages of electricity to cause the muscles to contract, thereby hampering your ability to move. This electricity is introduced, via pronged darts, directly into the muscles where it is of such magnitude that it overrides input from your nerves, whatever form that nerve input may take.

    35. Re:So when a tazer hits you by enharmonix · · Score: 1

      When you use front row tickets to the latest concert, you don't collapse to the floor twitching as the music starts. A theory is only valid until a counterexample is provided, so here goes: Lollapalooza. Dallas, TX. 1997. Featuring Devo. QED.
    36. Re:So when a tazer hits you by sumdumass · · Score: 1

      Umm.. the electricity could just be making sound as it jumps through the different layers of your body.

      I sya we actualy find the brown note and we will know for sure what it is!

    37. Re:So when a tazer hits you by monoqlith · · Score: 2, Insightful

      Sounds are energetic compressions in a medium - a physical solid.

      Electrical impulses are the flow of electric charge.

      They are completely, 100% different physical phenomena.

    38. Re:So when a tazer hits you by sumdumass · · Score: 1

      This give me an idea. I wonder if running small copper wires through you cloathing to you shoe and ground would cause this to stay ouside your body and negate any effects a tazer might have?

      Could the first cheap tazor proof vest be on the way here?

    39. Re:So when a tazer hits you by AxelBoldt · · Score: 1

      some neurologist stick needles into your arms and hands to measure the electrical potential traveling along the nerves of the arm from shoulder to hand.
      They postulate that the nerve signal travels as a soliton sound wave along the nerve's membrane. Such a soliton changes density and thickness locally, and since the membrane contains lots of polar and electrically charged particles, it will create an electric signal that's measurable. That doesn't mean that the signal was transmitted electrically though.
    40. Re:So when a tazer hits you by sumdumass · · Score: 3, Funny

      What about the brown note?

    41. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      A TASER fires a pair of darts. One dart acts as the electron source, and the other is the ground. You wouldn't need to get wires down to your shoes -- just between the darts. If you want clothing that's electrically conductive, go to a fencing supply shop.

    42. Re:So when a tazer hits you by epee1221 · · Score: 1

      So the question can be simplified:
      Are the ion channels in the axon membrane opened by sound or voltage?

      --
      "The use-mention distinction" is not "enforced here."
    43. Re:So when a tazer hits you by Tsaot · · Score: 1

      Besides the fact that anything I find on this first states that it is a myth, they also say that the resonance is with the bowel itself, not the nerves controlling it.

    44. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      You, sir, have a very strange sense of humor.

      I think I would not like to be a party to any of your jokes.

    45. Re:So when a tazer hits you by Tatarize · · Score: 4, Interesting

      Well if you coat yourself with a conductive material, you would become in theory a sphere and thus have no electricity on the inside of the sphere. Not sure how much weaving and conductive stuff it would take to mostly negate the effect, but it could be done if it was done completely. Though if you make a capacitor vest and shock the bastard back... that'd be cooler and less practical.

      --

      It is no longer uncommon to be uncommon.
    46. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      That is a nice straw man you've created. You might want to sit in on some "Logic 101" classes with your friend.

    47. Re:So when a tazer hits you by jwiegley · · Score: 1

      Didn't you read... sound makes us tic.

      --
      I will never live for sake of another man, nor ask another man to live for mine.
    48. Re:So when a tazer hits you by M3SS3NG3R · · Score: 1

      Well if you coat yourself with a conductive material, you would become in theory a sphere and thus have no electricity on the inside of the sphere. First of all, you only get no electric field/charge on the inside if you are a perfect conductor. Second of all, the shape doesn't matter. A uniformly charged sphere is a perfectly physical object as long as it is NOT a perfect conductor.
    49. Re:So when a tazer hits you by omnispace · · Score: 1

      Current doesn't travel. Charges travel.

    50. Re:So when a tazer hits you by Anpheus · · Score: 1

      Wind is just an extremely long frequency wave resulting from large regions of different pressure. The wave of course, won't be merely a sign wave, because the wind can be affected by the surroundings, other pressure regions, particulate in the air, etc.

    51. Re:So when a tazer hits you by RealGrouchy · · Score: 1

      In the same way one can conclude that just becuase body reacts to bullets means that it uses bullets internally, which is nonsense
      ...nonsense, unless you're Chuck Norris.

      - RG>
      --
      Hey pal, this isn't a pleasantforest, so don't waste my time with pleasantries!
    52. Re:So when a tazer hits you by glitch23 · · Score: 0

      The voltage does not matter. It's not what is coursing through your body. The voltage is only the differential, not the actual electricity. Tazers use about 20,000 but the amperage is only a milliamp or so (more than 3 going thru the heart will kill you). Multiply those together to get the power output. High voltage transportation lines can have 100k or more volts but they also have a lot of amperage too. Anytime anyone says anything related to the amount of voltage and the fact that it would hurt you doesn't know what they are talking about. You can have a million volts but if you reduce the amperage the total power is hardly anything and with the low current it wouldn't be lethal or paralyzing.

      --
      this nation, under God, shall have a new birth of freedom. -- Lincoln, Gettysburg Address
    53. Re:So when a tazer hits you by glitch23 · · Score: 0

      I just don't get what makes you lot tick.

      We can't tell you because it is illegal in 48 states (but the norm in Holland).

      --
      this nation, under God, shall have a new birth of freedom. -- Lincoln, Gettysburg Address
    54. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      What stops energy from changing its manifestation?

    55. Re:So when a tazer hits you by grolschie · · Score: 1

      Umm.. the electricity could just be making sound as it jumps through the different layers of your body.

      I sya we actualy find the brown note and we will know for sure what it is!

      Would that be the note that affects ones sphincter ani externus?
    56. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      > What stops energy from changing its manifestation?

      Cutting a speaker wire?

    57. Re:So when a tazer hits you by had3z · · Score: 1

      I think that would be coffee.
      Hmm, maybe the body uses cafeine instead of sounds :)

    58. Re:So when a tazer hits you by Mark_MF-WN · · Score: 1
      Nerves react to electricity, but that doesn't require that electrical conduction is the method by which signals propagate. The potential change across the membranes in neurons may be an effect, not a cause. It could be even more complex, with the soliton causing the potential change at its leading edge, which in turn keeps the soliton focused as the it passes (solitons generally do occur in systems that are changed by the soliton as it passes).

      One article does not make a new paradigm, but it's interesting nevertheless. Hopefully new experiments will generate data that confirms or denies the theory. But mindless dismissal of something because it challenges conventional ideas? That's precisely the kind of thing that holds science back, and leads to intellectual weaknesses like conservativism and jazz-appreciation.

      Incidentally, the release of heat from chemical processes can be measured with extraordinary precision. Heat does not get "lost in the thermal noise". The very concept contradicts thermodynamics; any heat that is produced increases the level of thermal noise by definition. We're not talking about some quantum process that slips below the radar; cells are big, classical entities, and nerves are giants among cells.

    59. Re:So when a tazer hits you by ScrewMaster · · Score: 1

      Alessandro Volta himself, who managed to make a pair of frog's legs jerk when applying a current from one of his primitive batteries is presently sitting up in his crypt saying, "WTF? I could've just clapped my hands?"

      --
      The higher the technology, the sharper that two-edged sword.
    60. Re:So when a tazer hits you by sumdumass · · Score: 1

      That would depend on if i knew what ones sphincter ani externus means. I'm to lazy to look it up, So could you give me a hint? And yes, I havn't had the cranial rectal extraction proceedure that I have been saving up for. If you could donate, It might give a swift kick in getting the proceedure done.

      BTW, I was talking about the famous brown note that makes you shit your pants. You know the one that has always been done as a weapon by some now dissasembled military special ops program or caused by poor sterio equiptment in the disco sceene.

    61. Re:So when a tazer hits you by cp.tar · · Score: 1

      That's just what they want you to think...

      --
      Ignore this signature. By order.
    62. Re:So when a tazer hits you by sumdumass · · Score: 1

      Besides the fact that anything I find on this first states that it is a myth, they also say that the resonance is with the bowel itself, not the nerves controlling it.
      Lol.. well, what if it isn't a myth and the reason they think it is a myth is because they were trying to make the bowls itself do something instead of the nerves controling it?

      I'm not arguing for it one way or another. I'm just saying that, if this researcher is corect, then we have been looking to recreate or prove/disprove the brown note entirly wrong. And the myth had to start somehow.

      And while you don't colapse form the music, you do get wild urges to dance, do something rthimic, or rush the stage to get stunned by the security guards. What if these urges aren't the brain thinking le get jiggy and is instead suttle impulses from your nerves telling the brain your wanting to do something. This could be simular to scratching a dogs side when he instinctivle starts kicking his foot thinking he is doing it. His nerves are telling his brain that something is going on and he is reacting to it.
    63. Re:So when a tazer hits you by Caffeinate · · Score: 1

      I hate to be a spelling Nazi, but seriously - a sign wave? Is that how deaf people acknowledge each other from across a room?

      --
      Godless heathen.
    64. Re:So when a tazer hits you by jellomizer · · Score: 1

      Or the nerve cells being damaged by electricity start sounding different singles to make the muscles flex. Because unlike other stimuli Heat, Pressure and Light and even sound, electricity goes thew the conductive body and triggers a lot of cells much more deeply then other stimuli. Causing the muscles to contract. Sometimes we confuse effect with cause. Because it is the best that we know. But why if you build up static and you touch a doorknob why doesn't you whole body go into convultion not just a reflex from the point that is getting the shock.

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    65. Re:So when a tazer hits you by AmberBlackCat · · Score: 1

      Well I think we need to upgrade to fiber-optics and see if we can improve our response time.

    66. Re:So when a tazer hits you by ScriptedReplay · · Score: 1

      Well if you coat yourself with a conductive material, you would become in theory a sphere and thus have no electricity on the inside of the sphere.

      Wrong. A conductor shell would screen you from (relatively long-wavelength, depending on your setup) external variations of electrostatic potential. Whatever variations are generated inside the shell are not affected - turn a flashlight on inside a Faraday cage and it will still work.

      In order to 'have no electricity on the inside of the sphere' you'd have to have the enclosed volume conductor in the first place, hence no need for a conductive coating. Not to mention that it's a static equilibrium that you're describing.
    67. Re:So when a tazer hits you by x_terminat_or_3 · · Score: 1

      And you don't even need a big current.

      I think it was a navy man that killed himself with a 9V battery by placing the two electrodes on an open wound on the opposite side of his body.

      --
      Only those who risk going too far can possibly find out how far they can go. T. S. Eliot
    68. Re:So when a tazer hits you by Antique+Geekmeister · · Score: 2, Informative

      Slow down: The Hodgkins Huxley model of neural conduction is far too well supported by experiment, and by the observed behavior changes of nerve in response to ionic concentrations. You can't just throw that out due to a lack of thermal effects.

      Moreover, "heat produced by electrical conduction" and the like have to come from somewhere. The amount of energy processed by a cell is limited mostly by glucose metabolism. (We could chat about protein metabolism as well, but let's not get distracted.) That glucose metabolism and related heat production for keeping the cell active in other ways is far higher than that one would expect from electrical conduction by any model I know: delicately measuring "resistive" losses (which do not quite mean the same thing in electrolytic conduction, let me tell you!) is like measure the paint on rocks in an avalanche. You don't bother to measure it by heat or weight, you measure it by more obvious factors like color (or electrical potentials, in this case, since HH style experiments demonstrate it quite well).

      Fortunately, the actual original article is much better than the confusing and misleading analysis in the Slashdot lead-in and the linked article.

    69. Re:So when a tazer hits you by OmpKoi · · Score: 1

      Proving that nerves behave as if to operate by electricity at certain experiments and as sound at different times, dubbing the phenomena sound-electrical-nerve-duality.. only to be explained years later by quantum-physiology

    70. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      "... just because body reacts to bullets means that it uses bullets internally, which is nonsense."

      Well, in fact, it does.

    71. Re:So when a tazer hits you by Tatarize · · Score: 1

      What next Mr. Science guy... Adam and Eve DIDN'T ride to church on dinosaurs?

      --

      It is no longer uncommon to be uncommon.
    72. Re:So when a tazer hits you by Anpheus · · Score: 1

      What the hell? I swore that I wrote a reply to chastise myself. Maybe I didn't wait the 15 seconds or minutes or somesuch though.

    73. Re:So when a tazer hits you by grolschie · · Score: 1

      That would depend on if i knew what ones sphincter ani externus means. I'm to lazy to look it up, So could you give me a hint?....

      ....BTW, I was talking about the famous brown note that makes you shit your pants.
      Ah yes, that be the one: sphincter ani externus. :-)
    74. Re:So when a tazer hits you by Anonymous Coward · · Score: 0

      The electricity triggers the neuron's action potential to be reached due to the difference of polarity resulting from the shock. The actual transmition of information along the axon doesn't necessarily have to be electricity, and sound vibrations would explain why no heat is expelled during energy transfer (as outlined in the Law of Thermodynamics).

      Being "Tazered" results in muscle contraction because the initial firing of the neuron is via electricity (this is not disputed). Sticking your head in a bell and sounding it would cause some confusion, however the initiation of sound vibrations must occur inside the Axon Hillock in order for the cell to understand its message (much like sound needs to pass through the three inner ear bones in order for the brain to understand "sound").

  2. Raised eyebrows... by BWJones · · Score: 5, Interesting

    As a neuroscientist who has a healthy respect for a little anarchy from time to time, I have to call shenanigans on this one. I'd love to kick down the doors on some fundamentally held beliefs (my dissertation did something close to that), but this had me laughing out loud.

    I've recorded from nerve cells in the classical manner and run the parametrics on different ionic concentrations and it would take quite a solid argument backed up by data for me to displace any of the credibility built on the classic Hodgkin and Huxley work.

    --
    Visit Jonesblog and say hello.
    1. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Could it be a combination of these?

    2. Re:Raised eyebrows... by myc · · Score: 5, Informative

      IAAANS (I am also a neuroscientist) and I'm with you on this. TFA sounds pretty crackpot to me. If they really had strong evidence for this it would be published in Nature, not Biophysical Journal.

      --
      NO CARRIER
    3. Re:Raised eyebrows... by dgatwood · · Score: 1, Redundant

      Indeed, if it were true, I could shout at my hand and either I'd feel something or it would twitch or something. Sound waves permeate tissue way, way too easily to be isolated. This may be the most ludicrous article I've ever not read. :-D

      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

    4. Re:Raised eyebrows... by TubeSteak · · Score: 4, Informative

      Here's the actual article
      http://www.biophysj.org/cgi/rapidpdf/biophysj.106. 099754v1.pdf

      They build upon Meyer & Overton's work & specificly say that Hodgkin-Huxley is not satisfactory with relation to anestethics.

      My question is: Does the Meyer-Overton rule mean that elephant tranquilizers are 10,000 more times soluble than morphine?

      --
      [Fuck Beta]
      o0t!
    5. Re:Raised eyebrows... by TooMuchToDo · · Score: 0, Offtopic
      If you AND the parent poster are neuroscientists, you two need to get crackin' on my neurointerface to increase the data rate between me and my computer and the net.

      Of course, I kid. But I hope you two get to do some cool research.

    6. Re:Raised eyebrows... by Anonymous Coward · · Score: 5, Interesting

      As another neuroscientist, I would urge you to keep an open mind. Perhaps they mean the frequency of events fall neatly into the sound frequency range: i routinely see 20-200 Hz E/IPSC at RT, and much higher in larger neurons at 37'C. You can get action potentials at up to 1000 Hz in auditory neurons.
      If anything, try plugging in a speaker into your patch-clamp amplifier's audio port and see how it sounds (Back in the days I would directly convert the frequency and amplitude of the events in my voltage-clamp traces to raw PCM and play that out, and it sounded like some kind of a pothead techno mix tape, something you could definitely listen to and even enjoy.

      Certainly, the movement of ions across the membranes is what drives most neurons (forgetting about the slower metabotropic communication, kinases, etc. for a second), but perhaps thinking of these in terms of frequencies would help non-math people appreciate the neuronal communication (the concept of a choir singing in a labyrinth is a lot easier to grasp for a layman than even the most basic HH multivariable d.-equation models).

    7. Re:Raised eyebrows... by Tsiangkun · · Score: 0, Redundant

      nature, cell, science, . . .

      This type of over throwing of a widely established model would be major news, and would not be published in some 'me too, add my brick to the pile' journal.

    8. Re:Raised eyebrows... by dan828 · · Score: 4, Informative

      Looks like it actually made PNAS about a year and a half ago. http://www.pnas.org/cgi/reprint/102/28/9790

      Either way, the summary and the linked article look to be way off base.

    9. Re:Raised eyebrows... by ridgecritter · · Score: 1

      Um, yeah, I'm an escaped neuroscientist, I've done extracellular and intracellular recording from single and multiple neurons in both vertebrate and invertebrate systems, and I think this extraordinary claim needs its extraordinary proof. Most recording methodology would be able (in fact, couldn't avoid) to pick up sonic signals. It'll be interesting to follow this. If even partially true, might be cause for rethinking routine use of ultrasound scans of kids in utero.

    10. Re:Raised eyebrows... by Kahai · · Score: 5, Funny

      I'm also a neuroscientist and I'd like to say I find this research credible and also true. Sincerely, Essjay

    11. Re:Raised eyebrows... by kf6auf · · Score: 2, Insightful

      There is a lot more information needed here. For those of you who haven't read the article, don't bother. Here is a summary: Some crackpots think neurons don't use electricity* because they don't get warm. Therefore, they use sound waves. First of all, there appears to be no reason to suggest sound waves. Second, sound waves are not perfect transmitters of energy either. Some of it will bleed off as heat. So it seems to me that the very reason that they think it's not electricity* precludes it from being sound waves unless neurons are somehow made of an ideal medium. IANA Neuroscientist but I have taken neuroscience classes and neurons don't conduct electricity. They open gates for ions to flow from areas of high electrical (and chemical?) potential to areas of low electrical potential, decreasing the voltage between the inside and outside of the neuron which then causes the next set of gates down the line to open. Not that I expect the article to get it right.

    12. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Ok, I am _not_ a neuroscientist, but I think a little commonsense could easily debunk this. Why not just sample the speed of transmission and measure it against the speed of sound in the medium vs. the speed of electricity in the medium? Or does the proposed soliton situation mess with the speed of sound that much?

    13. Re:Raised eyebrows... by Anonymous Coward · · Score: 0
      I, for one, want to be the first to congratulate our new Neuro iPod-bearing overlords. The Neuro iPod doesn't come with earpods. No, it comes with electrodes that can be stylishly attached to your temples to allow the sound to be conducted straight to your brain. Although with hip-hip, it's possible there is no brain involved anywhere in the whole process. But anyway, your entire nervous system will throb and pulse to the beat until it overloads and you die. Ah, art has its price sometimes.

      Coming soon, the Neuro CellPhone, which allows you to drive and talk handsfree until you have that fatal accident because of not paying attention to the road. Which is proof Darwin was not only right, but a genius.

      Yeah, I did get up on the wrong side of the bed this morning, and every day since the 2000 elections.

    14. Re:Raised eyebrows... by AxelBoldt · · Score: 1

      As a neuroscientist
      ... you can surely explain how anesthetics work, why the strengths of vastly different anesthetics seem to be solely determined by their membrane solubility (Meyer-Overton law), and why the effects of vastly different anesthetics can all be reversed by applying pressure, by lowering the temperature, or by lowering the pH?

      Because all of that is explained by their model, as outlined in their first and second articles.

      In short, it goes like this: by dissolving in the membrane, anesthetics lower the melting point of the membrane, thereby affecting its sound propagation properties. The lowering of the melting-point can be reversed by applying pressure, lowering temperature, or by lowering pH. So by assuming that the nerve impulse is transmitted by a soliton in the membrane, everything is explained.

    15. Re:Raised eyebrows... by Zombywuf · · Score: 1

      Shenanigans? I'll get my broom.

      --
      If you can read this you've gone too far.
    16. Re:Raised eyebrows... by jlowery · · Score: 3, Insightful

      IANANS, but the nerve impulses are electrochemical impulses, so they're not analogous to electrons racing down a copper wire. The chemical aspect slows things down quite a bit.

      --
      If you post it, they will read.
    17. Re:Raised eyebrows... by cheater512 · · Score: 1

      What annoys me is they are saying 'This cant be right. Lets find something which could explain it. Oooh Sound!'.
      There isnt any actual evidence that it is sound.

      If it is sound then whats the magic frequency to cause the loss of muscle control?

    18. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      If that is true, then how come some anesthetics (eg. pentobarbital) can act only on certain neurotransmitter systems, such as GABA? That fact does not jive with a the idea that it is membranes in general that are affected. Also, conductances across neurons (and cellular function in general) is dependent on temperature, pH, and mechanical strain, so invoking them does not help your case.

    19. Re:Raised eyebrows... by iminplaya · · Score: 1

      Yes, well, they certainly have crossed into a brave new world.

      --
      What?
    20. Re:Raised eyebrows... by mrbluze · · Score: 1

      Although IANANBUAAMD (I am not a neuroscientist but am a medical doctor), I must also contend that the soundwave theory cannot hold. Although specialized nerves do have vibration sensability, and of course the ear is specialized to picking up sound in a most fascinating way.

      Many theories have been put forward to explain the function of the brain and the way drugs work (some of the most creative explanations have been used to try to explain the action of inhaled anaesthetic drugs), but time and time again it's simple, boring old biomolecular interactions with receptors and neurotransmitters, causing demonstrable and measurable ion fluxes, which in turn cause electrical currents which can be measured at the nerve level and at the skin (Electroencephalography).

      Although it is true that nerve membrane perturbation, caused by vibration or other mechanical stimulation, can be a trigger for nerve conduction - it is pretty difficult to believe that a nerve impulse can travel as quickly as it does (sometimes as fast as 100 metres/sec), without dissipating, without much cross-talk, and with measurable electrical current, and yet be due to sound waves (kinetic energy). Not only that, but my guess is it would be rather inefficient if it were possible, and just on that basis, Nature would have rejected it for cheap, easy electrochemical conduction.

      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    21. Re:Raised eyebrows... by DrVomact · · Score: 1, Insightful

      It's peculiar that neither of you "neuroscientists" took the opportunity to point out that neural signals are not electrical impulses--they're electrochemical state changes that propagate along nerve axons at a pretty sedate speed (measured in feet per seconds), and not any form of electrical current akin to what flows through a wire when you connect it across the poles of a battery (or pass the wire through a magnetic field, or whatever). The current in the wire travels quite a bit faster than 60 fps...

      The misconception that the brain is full of little conductors, and that its operation is just like a computer, with electrical voltages and organic logic gates giving rise to "thoughts" is dear to the common mind. This misconception is responsible for the glamour exercised by one of the great follies of the age: the notion that we are in an essential and important way like computers, and that computers could be made to be--in some deeply significant way--like us.

      As "neuroscientists" you know better than this, of course. The broad outlines of what happens when a neuron transmits a signal are pretty uncontroversial (though I'm sure that there are plenty of spirited arguments about the details). This article wasn't an attack on your views, but on the popular belief.

      Perhaps the perpetrator of the article was trying to let a little air out of that particular balloon? Then again, I suppose my surprise would not be too great if I were to learn that some theoretical physicists are so truly dull as to think that they could teach neurophysiologists a thing or two. An interdisciplinary education is a rare phenomenon these days, and the specialists never bother talking to each other--let alone to us normal geeks.

      By the way, IANANSIAAP (I am not a neuroscientist, I am a philospher.

      --
      Great men are almost always bad men--Lord Acton's Corollary
    22. Re:Raised eyebrows... by anaesthetica · · Score: 5, Funny

      As another neuroscientist, I would urge you to keep an open mind.

      Is this an example of the fabled neuroscientist humor?

    23. Re:Raised eyebrows... by mrbluze · · Score: 1

      The scientists, whose work is in the Biophysical Society's Biophysical Journal, suggested that anesthetics change the melting point of the membrane and make it impossible for their theorized sound pulses to propagate.

      This is indeed an attempt to resurrect the Meyer Overton hypothesis, which, in medical teaching, has been relegated largely to the realm of historical interest and no-longer used as a viable explanation for how anaesthetics work.

      Recent work involving knock-out mice (mice with a gene for a receptor removed) have shown dramatically reduced efficacy of volatile anaesthetic agents in these mice when they have no GABA receptors (Gaba-amino-butyric-acid). Such findings strongly suggest a receptor interaction for mode of effect. That kind of evidence is quite strong.

      The painful thing is, though, that the research these scientists have conducted will inevitably become examinable material for the anaesthetic first-part exams. Argh!! Not another crazy theory to include in a 10 minute written essay on the topic!

      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    24. Re:Raised eyebrows... by scum-e-bag · · Score: 1

      It's peculiar that neither of you "neuroscientists" took the opportunity to point out that neural signals are not electrical impulses--they're electrochemical state changes that propagate along nerve axons at a pretty sedate speed (measured in feet per seconds), and not any form of electrical current akin to what flows through a wire when you connect it across the poles of a battery (or pass the wire through a magnetic field, or whatever). The current in the wire travels quite a bit faster than 60 fps...


      Boom Boom... ...just like a snare drum with sand on it, particles move into shapes and patterns depending upon the vibrations from the snare. Last time I checked, the "electrical impulses" in the brain were caused by the differing movement and dispersion of ions... shake shake... move move... boom boom... ion pattern!!!
      --
      Does it go on forever?
    25. Re:Raised eyebrows... by thrawn_aj · · Score: 5, Informative
      Note: I think the main link in this thread has incorrectly summarized the article. I just read the original article and the headline is just plain wrong IMO. I tried to give my interpretation of this work here:

      I will say that their physics seems reasonable - one should understand that when we say "sound" there can be several meanings to that word. In the article, they are talking about piezo-electric pulses which I can visualise as a pressure wave that creates voltages between synapses (forgive me if I'm murdering the biology here ;-)). Imagine your usual piezo-crystal (a simple example is the one in a wristwatch) that vibrates (pressure waves) when a voltage is applied. Well, the reverse can also happen (this is used in some species of microphones). The way I visualize their model is that a piezo-electric soliton (if I remember my group theory, it's a sort of a quantized sound wave which persists without being destroyed by background noise because it has a topological quantum number asociated with it) travels between synapses leading to a voltage between them. Now, the pressure wave exists in the surrounding medium, which contains the ions in solution. So, at the most one can interpret these findings to mean that neural conduction is more like current in a superconducting wire than electroplating :D. This is the essence of their transport theory (as I understand it).

      Another thing to note is that the article is not written as a maverick physicist would. It is written in a way that only a proper experimental physicist would - theory -> prediction -> experiment -> comparison. And the thing they are evaluating is actually the effect of anasthetics on neural transport. So, they are simply not claiming stuff as the news site falsely overhypes. I for one find this article fascinating even though biophysics is not my field.

      I don't see how this translates to the sensationalist headline (although it's not the poster's fault, the linked site is a Canadian news site. The fact that it's Canadian is irrelevant :D, but the fact that it's a news site is rather telling. Also, they couldn't reach the authors for comments, which probably explains the awkward spin on the research.

      IAAANS (I am also a neuroscientist) and I'm with you on this. TFA sounds pretty crackpot to me. If they really had strong evidence for this it would be published in Nature, not Biophysical Journal.

      I'm afraid Nature is rather conservative in that respect and their editorial policy is at least partly based on maintaining or raising their impact factor (it is a highly profitable publication after all). The only way they can do that is by ensuring that only articles that are likely to be frequently cited in the future are published (that's the critical number that figures in the calculation of impact factor). As a result, the argument that any ground-breaking research would be automatically published in Nature is simply not true. Quite the contrary in fact. Now, before people mistake this for flamebait :P, I'm simply saying that Nature prefers the "wait-and-watch" routine, sorta like the Nobel committee, which is notorious for awarding A. Einstein with the prize for the photoelectric effect and not special or general relativity :P. I'm sure Nature will publish these guys a few years down the road after they have garnered enough of a reputation (IF they are correct that is!).

      I was just trying to point out the decisions involved in publishing with Nature. If people want to publish something quickly that will spur interest and spawn more research in that particular area, they do NOT publish in Nature; rather they would publish in a more "everyday" journal like Biophys. A Nature publication (unless you research frogs; for some reason frogs are hot in NATURE =D) is sorta like a fine wine. You just can't afford to waste time on it everyday ;). Plus, its rather dishearten

    26. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Hodgkin-Huxley equations model nerve impulse generation, originally in the squid giant axon and later extended to include various voltage and receptor gated ionic channels in nerve cell membranes.
        Equating this to anesthetic uptake should be modded offtopic :-)

    27. Re:Raised eyebrows... by jabuzz · · Score: 5, Informative

      IAAP (I am a physicist) and an electical current is the movement of electrical charge. Consequently your "electrochemical state changes that propagate along nerve axons" are in fact electrical currents in the strictest sense of the word. When we have moving charge we have a current end of discussion.

      The fact the propagation speed is much lower than when the electrical charge is an electron and the medium is a metal is entirely irrelevant. Lots of mediums exist that propagate electical current at much slower speeds than metals. I would also point out that propagation speed of an electrical current bears no relation to the velocity of the charge carriers either.

    28. Re:Raised eyebrows... by nih · · Score: 1

      I'm also a neuroscientist and so's my wife

      --
      I'm a rabbit startled by the headlights of life :(
    29. Re:Raised eyebrows... by Cstryon · · Score: 1

      I'm no neuroscientist. But when it comes to nerves being controlled by sound, it makes me wonder why when I hear base blasting, enough to feel the sound waves, why do I still have complete control of my body? MAYBE they mean that the nerves are controlled by sound because the music makes me want to DANCE o\- o/- o\-|

      --
      Indoctrinate : to instruct especially in fundamentals or rudiments Educate : to develop mentally, morally, or aestheti
    30. Re:Raised eyebrows... by Anonymous Coward · · Score: 1, Insightful

      it made it to PNAS as a communicated article

      PNAS is funny like that... Of what I've read there, there seems to be a difference in quality between track II peer review and communicated articles. not to crap on this paper, that i havent read.

      and the argument that this new biophys journal paper must be crap because it wasnt in nature or science is bullshit. good science gets published everywhere, and you do yourself a disservice by limiting your reading to popular magazines.

    31. Re:Raised eyebrows... by SQL+Error · · Score: 2, Informative

      Electrons don't race down copper wires. The electric field moves at a good fraction of the speed of light, but the electrons themselves move at something like one metre per hour.

    32. Re:Raised eyebrows... by arachnoid · · Score: 1

      "It's peculiar that neither of you 'neuroscientists' took the opportunity to point out that neural signals are not electrical impulses--they're electrochemical state changes that propagate along nerve axons at a pretty sedate speed (measured in feet per seconds)," They are in essence electrical impulses, transmitted by way of a complex system involving ions rather than electrons. The essential idea is the same -- an electrical signaling system. " ... and not any form of electrical current akin to what flows through a wire when you connect it across the poles of a battery (or pass the wire through a magnetic field, or whatever). The current in the wire travels quite a bit faster than 60 fps..." On the contrary, electrons move along a wire at a rate measured in millimeters per second. But this misses the point that it is the rate of change in current flow that transmits information (and that propagates at high speed), not the current flow itself. This is true for both biological nerve impulses and electrical flow in a conductor.

    33. Re:Raised eyebrows... by maop · · Score: 1

      The method of transport of information is irrelevant. Just because the brain and nervous system uses a different method of transport and has a different architecture than man-made computers does not mean the brain is not a computer. Yes, we are merely natural robots. No there is no such thing as the non-physical. Yes, you can get an "is" from an "aught." Now that I've solve all of philosophy for you I will go to bed.

    34. Re:Raised eyebrows... by maop · · Score: 1

      I meant to say "aught" from an "is."

    35. Re:Raised eyebrows... by Ceriel+Nosforit · · Score: 2, Interesting

      IANAPhy, but I study EM fiercely.

      Seems to me that when you said "in the strictest sense of the word" you put the word of the law above the math of the law. Since we're talking about a change in EM propagating through space we're dealing with AC rather than DC, and when dealing with AC we're dealing with the EM fields and not the charged particles mediating the fields. The EM fields of course move at c, and since the signals propagating through the nerves move a lot slower than that, we probably should conclude that AC isn't the mediator of the signals.

      The EM fields are much, much stronger close to the charged particles in the neurons, and it is a chain-reaction caused by one charged particle in very close proximity to the next that propagates the signal. One could say that every link in the chain-reaction in the nerves is an amplifier that ensures that the signal is just as strong when it reaches its destination as it was when it was emitted. Were we talking about EM fields, the field strength and therefore the recoverable signal, would diminish at an extremely fast rate since water (which we're mostly composed of) is a very poor conductor of the magnetic field, and an isolator when completely pure. Even if the neurons did communicate with EM fields, we'd be rendered inoperable thanks to the very strong background radiation we're constantly exposed to.

      In conclusion; neurons do not communicate with electrical currents, but with chemical reactions.

      --
      All rites reversed 2010
    36. Re:Raised eyebrows... by mrbluze · · Score: 2, Interesting

      The Meyer Overton Hypothesis specifically relates to volatile (inhaled) anaesthetic agents, and NOT morphine which clearly has a receptor based mechanism of action. It's not correct to use the hypothesis for drugs such as opioids, or barbiturates (eg: thiopentone/pentobarbital), for which a receptor based mechanism of action has been established.

      So, no, it doesn't predict the potency of most drugs, just the inhaled ones whose potency is directly proportional to solubility in octanol or olive oil.

      --
      Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
    37. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Even the basic HH& Katz account very well for the effects of temperature, pH, and pressure.
      If you do not want to bother with HH, at least recall the following from your high school chemistry:

      -Nernst equation http://en.wikipedia.org/wiki/Nernst_equation
      -Ion activity equation: http://en.wikipedia.org/wiki/Activity_(chemistry)
      -Reaction rate http://en.wikipedia.org/wiki/Reaction_rate

    38. Re:Raised eyebrows... by Alioth · · Score: 1

      I thought nerve impulses were carried electrochemically by a wave of depolarizations? So not electrical as in signals on a computer bus (travelling close to the speed of light), but more like electrochemical waves (travelling much more slowly, like 120mph) - sort of like an electrochemical domino topple (well, except the dominos can right themselves afterwards). This is of course from school biology lessons, so I'm sure it's simplistic and probably mis-remembered.

    39. Re:Raised eyebrows... by Anonymous Coward · · Score: 2, Insightful

      IAAPWASTEIBP (I am a physician with a sound training especially in basic physiology), and would like to comment that, while the particulars of HOW electric impulses are transmitted along nerves are not entirely relevant here, a simple test will prove THAT they are. AC current at low voltage. Touch it, see your muscles twitch, feel the paresthesia. As long as you can't explain how sound could do the same, I'll stick to currently accepted theory, thank you very much.

    40. Re:Raised eyebrows... by koreaman · · Score: 3, Insightful

      Sorry pal but that's how science works. There's no better evidence for a model than the fact that it explains all obtained results.

      More to the point, there's no philosophically valid way to "prove" anything conclusively.

    41. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Perhaps they mean the frequency of events fall neatly into the sound frequency range:

      Sound frequency range ? Pressure waves are different from electromagnetic ones, dont think that frequency has alot to do with it.

    42. Re:Raised eyebrows... by cheater512 · · Score: 2, Informative

      I dont know if you RFA but tbey didnt exactly provide any data.

    43. Re:Raised eyebrows... by koreaman · · Score: 1

      That's because it's a news article and not a real scientific source. The real article published in the real scientific journal assumably has real data. (I haven't read it, as IANA Scientist and would understand little)

    44. Re:Raised eyebrows... by jasonoik · · Score: 1

      Actually, there is no end-to-end charge transfer, so i believe you would agree with me, there is no electrical current "in the strictest sense of the word" (at least there is definitely no closed circuit). Microcurrents can be observed loccally in the form of moving ions, but this movement is perpendicular to the nerve axon. Look up the term "action potential" and you will understand, i cannot explain this any better without a proper diagram.

    45. Re:Raised eyebrows... by Mr2cents · · Score: 1

      Time for a reboot. erm, I mean, time to get some sleep.

      --
      "It's too bad that stupidity isn't painful." - Anton LaVey
    46. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Don't be silly.

      I=dq/dt

      What more needs to be said?

    47. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Whhoooaa.. current BEARS? I thought we were talking bout humans...

    48. Re:Raised eyebrows... by OG · · Score: 3, Insightful

      If you know a member of the Academy, they can sponsor your paper and get it published in PNAS. I've read tons of bad articles in PNAS that got in that way.

      And while much good research is published all over the place, this is so groundbreaking that it would be a Nature paper if good enough. Nature/Science/etc publish good, "exciting" papers. Other journals publish good papers that just aren't high-profile enough for the top impact journals.

    49. Re:Raised eyebrows... by NeilTheStupidHead · · Score: 1

      There we have it folks, tiny bears carry nerve impulses to the brain!
      Now where's my article on the CBC?

      --
      Lose: misplace or fail || Loose: not bound together
    50. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      How does it feel to belong to a discredited profession?
      All the real thought abandoned you guys over the last 200 years.

    51. Re:Raised eyebrows... by eam · · Score: 1

      > The misconception that the brain is full of little conductors, and that its operation is just
      > like a computer, with electrical voltages and organic logic gates giving rise to "thoughts" is
      > dear to the common mind. This misconception is responsible for the glamour exercised by one of
      > the great follies of the age: the notion that we are in an essential and important way like
      > computers, and that computers could be made to be--in some deeply significant way--like us.

      You seem to be under the impression that a computer is something built out of transistors. diodes, resistors, wire, and other electronic components. Sure, if you reduce a computer to the narrowest possible definition, you could say that the human brain is not a computer, but I don't think that would be valid.

      From http://www.m-w.com/:

      computer - one that computes; specifically : a programmable usually electronic device that can store, retrieve, and process data

      I don't see anything there that excludes brains. There are other ways to build computers. Human beings haven't even scratched the surface yet.

    52. Re:Raised eyebrows... by teslar · · Score: 4, Insightful

      IAAN (I am a neuroscientist, yeah you knew that already) and, as they Physicist already explained, you are in fact describing electrical currents. So I agree with the other two neuroscientists, saying that the electrical models we have are wrong is just BS.

      There are plenty of valid criticisms you can bring to the HH model. It cannot account for all observations (there was a paper in Nature recently exactly to this point) and after all, when you try to model primate cells with HH dynamics, you are in effect comparing your monkey with a giant squid! It has tbh always amazed me how well that worked at all. So if you're going to say, HH is inadequate, that's fair. If you are going to say that non-electrical pathways for transmitting information exist alongside the known electrical currents, that's also fair and you have my complete attention. But you can't just say that nerves don't use electricity, that just labels you as someone trying to be sensationalist. Besides, if you could prove this beyond reasonable doubt, you should and would send the paper to Nature.

      Then again, this is my reaction to the /. summary above. I'd imagine the actual paper makes a more sensible argument, but I'm not going to read that before monday, so...

    53. Re:Raised eyebrows... by dlenmn · · Score: 1

      Indeed. The author of my EM text book notes that a current doesn't have to be electrons in a wire -- it might just as well be composed of trained ants carrying charges on their backs! (Griffiths 3rd ed, p 285)

    54. Re:Raised eyebrows... by Griim · · Score: 1

      No it makes sense...this is why defibrillators transmit sound instead of voltage.... ...oh wait...

    55. Re:Raised eyebrows... by tommyhj · · Score: 1

      Great post, thrawn_aj! I Was frowning quite a bit before stumbling over your post, which made me raise my eyebrows. This IS actually an interresting study, obliterated by popular media as it so often happens...

    56. Re:Raised eyebrows... by picob · · Score: 1

      Neural signals are not electrical impulses, they're electrochemical state changes

      I agree with your first statement, but your second doesn't tell me anything. What reaction in cells isn't an electrochemical state change? I would say neural signals are transmissions of neural membrane depolarizations.

      A neuron in 'rest' keeps a certain charge (polarization) on the membrane between the inside and outside of the cell. This costs energy in the form of ATP (a cellular currency for protein actions). Upon a depolarization, membrane channels and pores transmit ions and the charge in the membrane changes. This depolarization is later measured further along the axon (the neural extension that transmits depolarizations).

      This article wasn't an attack on your views, but on the popular belief

      No, he *is* attacking the traditional view:

      According to the traditional explanation of molecular biology, an electrical pulse is sent from one end of the nerve to the other (...) Heimburg and Jackson theorize that sound propagation is a much more likely explanation.

      I need more information to believe their theory. I do think their main argument is flawed:

      The physical laws of thermodynamics tell us that electrical impulses must produce heat as they travel along the nerve, but experiments find that no such heat is produced.

      How do you measure miniature temperature changes in a fluid? (Ok that's possible near boiling point, which it's not in your body). They will have to come up with a better way to falsify the current view. Their theory is interesting, however:

      A medium with the right physical properties could create a special kind of sound pulse or "soliton" that can propagate without spreading or losing strength. The physicists say because the nerve membrane is made of a material similar to olive oil that can change from liquid to solid through temperature variations, they can freeze and propagate the solitons.

      I expect they are referring with their 'olive-like medium' to the myelin layers (glia cells) that surround neurons. Myelin layers occur along the axon and are interrupted by nodes of Ranvier, where changes in membrane polarizations occur upon a 'pulse'. These Nodes of ranvier contain a lot of ion gates and channels. A change in membrane charge can be measured here.

      The current view is that the depolarization is transmitted by ions. Ions, outside the membrane are suspected to move from one node of Ranvier too the next. What I guess these Danish scientists will have to prove is that ions do not move but stay at their location. This may be possible by inducing a depolarization by radioactive ions, and measuring radioactivity along the axon at other nodes of Ranvier. If their theory is correct they won't see a spread of radioactivity, otherwise there is.
    57. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      I think when the above poster said electrochemical, he meant whole positively charged atoms, and not electrons. As the passing of electrons would generate heat, but not positively charged atoms, say Na+, K+ or Ca++.

    58. Re:Raised eyebrows... by camperdave · · Score: 2, Funny

      So... I for one, welcome our new leyden jar bearing insect overlords?

      --
      When our name is on the back of your car, we're behind you all the way!
    59. Re:Raised eyebrows... by Anonymous Coward · · Score: 1, Funny

      You have some nerve to even suggest that.

    60. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Neurons do not communicate with electrical currents but they do communicate using changes in electrical polarity. At rest neurons are more negative on the inside than the outside and there is greater solution concentration on the outside vs the inside. When a neuron is roused, gates on the membrane open up causing the inside of the cell becomes more positive. From there a wave of depolarization sweeps through the rest of the neuron. Even at synapse, neurotransmitters work on those flood gates on the other neuron--opening them up to cause depolarization. So the proper term still remains, Electrochemical reactions.

      While its not purely magnetic fields, Transcranial Magnetic Stimulation, is a technology being used to non-invasively affect neurons. Like i said though, not purely EM fields, TMS relys on strong osscilating EM fields to create EM induction inside the brain, so current is involved.

    61. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      By the way, IANANSIAAP (I am not a neuroscientist, I am a philospher.


      And it shows. Next time, please put the disclaimer upfront.

      The misconception that the brain is full of little conductors, and that its operation is just like a computer, with electrical voltages and organic logic gates giving rise to "thoughts" is dear to the common mind. This misconception is responsible for the glamour exercised by one of the great follies of the age: the notion that we are in an essential and important way like computers, and that computers could be made to be--in some deeply significant way--like us.


      You, as a philosopher, should know that the fact that two machines operate based on different principles doesn't mean they cannot be functionally equivalent. It's ridiculous. It's like saying that an electric toothbrush cannot be made --in some deeply significant way--like a hand operated one.
    62. Re:Raised eyebrows... by nine-times · · Score: 1

      As a neuroscientist, I'd like to post that I'm a neuroscientist for no reason other than to say that I'm a neuroscientist.

      Ok, so I'm not a neuroscientist. I'm a cowboy-astronaut!

    63. Re:Raised eyebrows... by YoungHack · · Score: 1

      The misconception that the brain is full of little conductors, and that its operation is just like a computer, with electrical voltages and organic logic gates giving rise to "thoughts" is dear to the common mind. This misconception is responsible for the glamour exercised by one of the great follies of the age: the notion that we are in an essential and important way like computers, and that computers could be made to be--in some deeply significant way--like us.


      It might be one of the great follies of the age, but recently I had a close family member die. It was her wish to be cremated, so her body wasn't embalmed and made up for viewing. At the funeral home, the close family viewed her before she went to the crematorium.

      It was different than seeing the made-up bodies at a viewing. I had this profound feeling that a person really is a very complicated machine, and that when the machine gets grossly out of whack it ceases to operate and you die.

      A gut feeling in one person doesn't preclude the existence of a soul. But I don't see that we aren't in some essential way "mechanical" even if we are not like (modern) computers.
    64. Re:Raised eyebrows... by odyaws · · Score: 1

      Note: I think the main link in this thread has incorrectly summarized the article. I just read the original article and the headline is just plain wrong IMO.
      Geez, no kidding. IAYANS (I am yet another neuroscientist (though on the theoretical end)), and the original article says nothing like the headline or the news story: here it is. The authors are just using thermodynamic arguments to say that the action of anesthetics may be explained by changes in membrane freezing point, which changes the propagation properties of electrical solitons (vaguely like sound waves). They specifically say at the beginning that this does not contradict the ion-channel view of propagation in the same way that thermodynamic gas laws don't contradict the fact that gasses are made of atoms flying around.

      As a neuroscientist, I find this article interesting and food for thought, but not earth-shattering as the summary seems to imply. As a person, though, it underscores the unsettling reality that we really have little to no understanding of how and why anesthetics actually work, which I guess is why they call it practicing medicine.

      --
      Still trying to think of a clever sig...
    65. Re:Raised eyebrows... by cascino · · Score: 1

      Sorry pal but that's how science works. There's no better evidence for a model than the fact that it explains all obtained results.

      More to the point, there's no philosophically valid way to "prove" anything conclusively.


      Yes, but without data to support a theory that "explains all obtained results" it's no better than saying "nerves use magic to transmit impulses" or "gravity is actually God's will in action."

      While it seems that the "question the institution!" crowd has come out en force on this matter (which is certainly not a bad thing, I think science requires constant evaluation of the prevailing opinion), it turns out that electrochemical conduction is a very well-documented phenomenon. True, there are discrepancies at time between the model and reality, but the discovery and isolation of the hundreds of actual proteins involved with propagation of an action potential makes us fairly certain we're on the right track. Note that there are also small discrepancies with gravity (actually big ones), light, DNA, thermodynamics, etc., yet those are generally accepted theories.

      Finally this doesn't relate to the parent post, but the slashdot writeup for this article is horrendous. It states the same information - that the old way is wrong, and that sound is correct - three times in a row. If you're going to submit a content-free writeup, at least keep it short.

    66. Re:Raised eyebrows... by lordmetroid · · Score: 1

      Well considering that molecules are pumped in and out from the interior. Sound is a wave in concentration of a substance. Molecules pumped in or out would probably push others aside and create a pressure wave or in other words sound.

      But from what I can remember you can induce a signal by an electric pulse as well so this doesn't sound plausible.

    67. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      IANAL (I am not a linguist) but WMUAIWJUTO (Why make up acronyms if we just use them once)?

    68. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      the journal where a paper is ultimately accepted is, unfortunately, not only based on the merit of the paper. there are other factors that play into whether a paper gets accepted into the popular magazines; its such a crapshoot, did the reviewer have a good nights sleep the night before? did she/he get fucked somehow by someone earlier, are they in opposing camps?

      saying that in general nature or science publishes good, exciting, work is a bit misleading; they definitely try to ride the wave of excitement, but quality work is not always exciting, and `exciting' work is not always quality.

      a lot of crap gets through, because of the right buzz words, right 50 person collaboration teams, and a peer review systems that has its flaws... (says the poor bastard whos never had a chance at either...).

    69. Re:Raised eyebrows... by Chrononium · · Score: 1

      I'm an engineer studying EM. I've heard that the signal carriers are more likely polarization waves (random college biology course), in which case it's not so much an EM field as it is electric fields and shifting charges. I know that you can derive polarization current if the signal frequency is high enough, but in either case, it implies that the charges remain within their respective dielectrics. This is especially believable given water's polar nature (you can deflect a stream of pure water with a strong magnetic field). If constructed correctly, nerve cells would have no problem communicating polarization waves, even if standard EM waves don't propagate well. Additionally, a polarization wave may end up looking exactly the same as a sound wave, depending on the molecular structure of the dielectric and wave propagation velocity. Finally, if such a wave (either a sound wave or polarization wave) was a soliton, then you definitely don't have to worry so much about all that background radiation. Look up solitons if you don't already know what they are -- it's a pretty cool phenomenon.

    70. Re:Raised eyebrows... by coblo · · Score: 1

      IAAN. The authors make one huge assumption that effects of anesthetics on membrane proteins like ion channels would have to be mediated by specific and direct binding. They suggest that the similar effects of anesthetics on a wide range of different neurons and different organisms precludes an effect on ion channels, because these proteins will be very different in those different cells/animals. This is a flawed argument due to above mentioned assumption.

      They're biophysical arguments support the idea that anesthetics change the Tm of the transition of the membrane from fluid (liquid-disordered) to gel (solid-ordered). The authors state that action potentials (nerve signal propagation) forces the membranes through 85% of this transition. They further state that this transition phase is distinguished by more compressible and more ion/molecule-permeable membranes. It is very likely that these two changes have effects on ion channels. The main players in action potentials are voltage gated ion channels, that have positively charged domains that must move through the membrane to control gating (although some people think these charges are not contacting lipids, many others think at least some of them do). Also, the opening of many, if not all of these channels involves some conformational change like a twisting that may be influenced by membrane compressibility (also fluidity and thickness) to varying degrees (an extreme example would be mechano-gated ion channels which can be opened by a stretching of the membrane away from the channel).

    71. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      yea, one metre per hour sounds about right. I typed this an hour ago, but the signal only just travelled down the metre long chord.

    72. Re:Raised eyebrows... by AxelBoldt · · Score: 1

      how come some anesthetics (eg. pentobarbital) can act only on certain neurotransmitter systems, such as GABA?
      Those few anesthetics must obviously work by a different mechanism, probably by interfering with some protein needed to produce or detect said neurotransmitter.

      conductances across neurons (and cellular function in general) is dependent on temperature, pH, and mechanical strain
      Yes, in a general qualitative manner. The authors are able to quantitatively predict how much pressure you need to reverse the effect of an anesthetic with a given membrane solubility.
    73. Re:Raised eyebrows... by certain+death · · Score: 0

      cricket....cricket....cricket....

      Ok...moving on now.

      --
      "My immediate reaction is "WTF? What kind of moron doesn't make things 64-bit safe to begin with?" Linus
    74. Re:Raised eyebrows... by cyclop · · Score: 4, Informative

      I can't but agree.

      I and my collegues did a research on the relationship between two distant methods of protein function regulation. We thought it was pretty nice, so we sent it to a bunch of very high-impact journals. Most of them sent it back even without giving it to referees. The only one that did refused us because we had a bad referee, and refused to even read our (long and detailed) response to his/her comments. So, less than year ago, we ultimately settled for a good but not top-most journal, where it was warmly accepted.

      A couple of months ago my group leader talked at a conference in USA where he talked also about the research in that article. An editor of one of the journals we tried to publish that more than a year ago came to my boss and said "Really nice and hot work, why don't you publish it for us?" The answer: "Because you didn't want it a year ago, and now it's already done."

      Why this sudden change? Because our proposed mechanism was not even a blip on the radar when we did it. In the meantime a recognized leader of the field published on Science a work that independently hinted in the same direction (even if in a very different and even less interesting way), and only because Mr.Guru created the buzzword now we are beginning to be taken seriously. Really sad.

      --
      -- Patent no.123456: A way to personalize /. comments with a sig attached to the end.
    75. Re:Raised eyebrows... by bennyp · · Score: 1

      Hahaha Scientists: This does not contradict any previous research at all. CBC: This directly contradicts the previous research. Sweet!

      --
      could it be?
    76. Re:Raised eyebrows... by cyclop · · Score: 2, Funny

      Hey, your Tiny Neuron Bears theory could fit well in the Flying Spaghetti Monster paradigm!

      --
      -- Patent no.123456: A way to personalize /. comments with a sig attached to the end.
    77. Re:Raised eyebrows... by Roger+W+Moore · · Score: 1

      No I would not. By that definition no circuit with a capacitor in it has a current which is clearly not correct using ANY sense of electrical current.

    78. Re:Raised eyebrows... by cyclop · · Score: 1

      BIF. (Because It's Fun)

      --
      -- Patent no.123456: A way to personalize /. comments with a sig attached to the end.
    79. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      IANANS, but I'd have to say that the sound wave is a pretty inefficient way to transmit signals. Nerves are surrounded by other tissues that could act as a damper. Imagine how much energy is being lost when transmitting a signal from your toe. If the signal must be strong to reach the brain, then the sound wave will affect the other nearby nerves which could cause confusion. It just doesn't sound right to me (no pun intended), but then what do I know... IANANS.

    80. Re:Raised eyebrows... by Roger+W+Moore · · Score: 1

      The EM fields of course move at c, and since the signals propagating through the nerves move a lot slower than that, we probably should conclude that AC isn't the mediator of the signals.

      Absolutely incorrect. There is a reason that 'c' is called the "speed of light in vacuo". That reason is because a vacuum is the place where EM radiation travels that fast. In different media there is no requirement that the speed be this great. Indeed if you buy coax cable you will find that the rated signal speed is ~60-70% of 'c' although you can get special air-core cables with speeds of 80-90% 'c'. Clearly on a coax cable the signal is being transmitted by the EM field. Indeed there is a form of radiation, called Cherenkov, that is emitted by particles travelling faster than the speed of light in the local medium.

      Might I suggest that instead of studying EM fiercely you study it carefully?

    81. Re:Raised eyebrows... by wtansill · · Score: 1

      I've recorded from nerve cells in the classical manner and run the parametrics on different ionic concentrations and it would take quite a solid argument backed up by data for me to displace any of the credibility built on the classic Hodgkin and Huxley work.
      But, like, we could all still be like, a skin cell under God's fingernail though. Right? Right? [takes another toke]
      --
      The contest for ages has been to rescue liberty from the grasp of executive power. -- Daniel Webster
    82. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      IAAANS (I am also a neuroscientist) and I'm with you on this. TFA sounds pretty crackpot to me. If they really had strong evidence for this it would be published in Nature, not Biophysical Journal.


      I agree TFA is definitely a crackpot hoax. (Sound also generates heat) Electricity is not conducted in nerves I do agree, however ionic gradients propagate along them accelerated by the properties of the myelin sheaths. A physicist might choose to label this as sound, but any chemist worth his salt (pun intended) knows better.

      However, Nature is a rag that will publish any populist crap that will sell, I'm much more inclined to trust papers in the Biophysical Journal, though this one must have gotten some pretty flakey peers for its review.
    83. Re:Raised eyebrows... by catmistake · · Score: 1

      It's not exactly electrical, is it? Electro-chemical, then?

      Electricity travels at the speed of light (say, in a vacuum), ~300,000 m/s... so if the brain is electrical, why is it that the "speed of thought" (ianan, so whatever this is really called, speed of nerve impulses or something) is so much slower at (correct this please) ~ 10 m/s? I mean, you'd expect it to be slower, but 30,000 times slower? Is the brain a poor electrical conductor? Does the brain make any sounds? What's the dillio on that, Doc?

    84. Re:Raised eyebrows... by pclminion · · Score: 3, Informative

      Well, the one meter per hour figure refers to the drift velocity. The electrons aren't actually flowing like water in a stream, they are bouncing around like mad at speeds much faster than one meter per hour but they have a slight tendency to drift in the direction of higher voltage. Averaged out, this drift velocity is very small but the electrons themselves are moving much faster.

      I think this is why so many people get confused by electricity. The FIELD moves almost the speed of light, but it makes electrons drift very slowly, even though the electrons THEMSELVES are moving rapidly. It's all very hard to visualize at first.

    85. Re:Raised eyebrows... by maraist · · Score: 1

      I'm not sure what you're trying to say. Maxwell dealt with this phenomina, not by declaring that current existing between edges of a capacitor, but by introducing a non-current term into the equations.

      curl E = -d/dt mag-flux
      curl H = Current + d/dt e-flux
      divergence D = total e-charge
      divergence B = 0

      My memory might have missed an minus sign somewhere or misplaced a flux with flux-density. But my point is that Current is a distinct parameter. The capacitor's changing electric-flux [density?]was Maxwell's contribution.

      --
      -Michael
    86. Re:Raised eyebrows... by pclminion · · Score: 1

      Because they are working in the realm of definitions, not theories. They are trying to say, "Look, these interactions share such and such characteristics with sound, therefore we believe it is appropriate to refer to these interactions as sound." They are throwing a definition out there, nothing more. People will either accept it or not. They are making no theoretical claims.

    87. Re:Raised eyebrows... by Angostura · · Score: 1
      I think the killer quote from the article is this:

      "The physical laws of thermodynamics tell us that electrical impulses must produce heat as they travel along the nerve, but experiments find that no such heat is produced."


      The quoted researcher seems to be assuming that there is some kind of current travelling down the nerve, rather than a wave of depolarisation. If this is the only basis for their assertion that sound is mediating nerve action (as it appears to be) then the guys at Copenhagen are smoking something most unusual... or have been subjected to some really strange sounds, whichever.
    88. Re:Raised eyebrows... by gardyloo · · Score: 1

      As another neuroscientist, I would urge you to keep an open mind. Perhaps they mean the frequency of events fall neatly into the sound frequency range: i routinely see 20-200 Hz E/IPSC at RT, and much higher in larger neurons at 37'C. You can get action potentials at up to 1000 Hz in auditory neurons.

            As a physicist working with acoustics, I would urge you to realize that the "sound frequency range" you're referring to has essentially zero measure when compared against the range of frequencies dealt with in "acoustics", and that "sound" occurs at frequencies ranging from a cycle per several millions of years (cosmological space and time scales) up to sub-Hz (geologic processes for example), through the audible range (20 - 20000 Hz) up to medical ultrasound range (0.7 - 10 MHz) and into the THz range (high-Q harmonic oscillators used in chemical sensors) and even beyond. So the "sound frequency range" can be utterly HUGE and only a tiny, tiny portion of it has anything to do with human hearing.

              That being said, these researchers ("not available for comment") are arguing that their proposed "acoustic solitons" are a newly-considered mechanism, but I don't think they are. As far as I can tell from the interesting --- but scientifically empty --- article, they're proposing ion-wave solitons as the method of nerve signal propagation. Solitons are certainly considered in acoustics, but to call this "sound" and NOT electricity is really kind of stupid. It's a (nonlinear) wave phenomenon, which is a regime into which huge numbers of phenomena fall, including many of acoustics, electrical effects, traffic patterns, plasma waves, etc. I *guess* that what they're saying is this: to get a soliton, you have to have a particular combination of conditions that just balance a couple of terms in the nonlinear material parameters describing the environment in which the waves propagate. These researchers claim that (perhaps) nerve fibers happen to possess this combination of characteristics, and anaesthetics can modify some of these terms just right to knock out soliton propagation. Interesting, but certainly no more "sound" than anything else.

    89. Re:Raised eyebrows... by lukesl · · Score: 1

      IAAN as well, and there are a couple of points. First, it's been known for years that the HH model is not always correct. There was something about voltage-dependent of Na+ channel inactivation, but I don't remember the details. Second, the HH model was originally for type II neurons, while most primate neurons are type I. However, about the point with the Naundorf et al. Nature paper--you should read the McCormick group's rebuttal. I found it very convincing.

    90. Re:Raised eyebrows... by lukesl · · Score: 2, Insightful

      I agree that the article is being somewhat unfairly trashed. I did a significant part of my phd thesis work on channel biophysics, and some of the things they're saying aren't as ridiculous as they initially sound. First, they say that the HH model doesn't explain everything, and I think that's probably correct. However, it doesn't claim to. It contains a number of experimentally-determined parameters about kinetics and voltage-sensitivity of gating, and it doesn't say where those parameters come from. And as of today, we can't derive those parameters from first principles and the channel structures, and there is plenty of evidence to support the idea that interaction between the channels and the lipid molecules is important. For example, membrane tension and stiffness affect voltage dependence of gating. So I guess one could say that even though the HH model doesn't explicitly take weird lipid interaction effects into account, it does so implicitly. I think that for this reason, their claim that membrane partitioning of anesthetics means that the phospholipid molecules themselves propagate the AP are highly suspect--the anesthetics could just affect the membrane properties, thereby affecting the channel properties (I haven't checked what the literature says about this, but I'm sure there's something).

      The second questionable thing about their argument (as I understand it, from a cursory reading) is that it implies that membranes are constantly perched at some sort of phase transition, which is temperature dependent. Then how do they explain that invertebrate neurons fire APs over a wide range of temperatures? You can take fruit flies at 15C and move them to a 35C incubator, and they'll keep walking around just like they were before. Looking at the curves in their PNAS paper, I don't see how that's consistent with their model.

    91. Re:Raised eyebrows... by thrawn_aj · · Score: 1

      The second questionable thing about their argument (as I understand it, from a cursory reading) is that it implies that membranes are constantly perched at some sort of phase transition, which is temperature dependent. Then how do they explain that invertebrate neurons fire APs over a wide range of temperatures? You can take fruit flies at 15C and move them to a 35C incubator, and they'll keep walking around just like they were before. Looking at the curves in their PNAS paper, I don't see how that's consistent with their model. Surely environmental temperature and body temperature are two completely different things. If you went out in freezing weather, your body would do all it can to MAINTAIN a normal internal temperature. If it can't you go into hypothermia, affecting (surprise) neural functions as well - you black out, the brain shuts down. Perhaps temperature is MORE important that thought previously. (Please note that I'm speculating on these things. I do NOT know the precise nature of a human blackout). The point is, your body will go through hell just to maintain body temperature, and there's more than one reason for that. This might be another ;-).
    92. Re:Raised eyebrows... by lukesl · · Score: 1

      That's what I'm saying--they're thinking about mammals, where temperature is highly regulated. In fruit flies (for example) this is not the case, and body temp = environmental temp. But fruit flies do have action potentials, and they are viable over a wide range of temperatures.

    93. Re:Raised eyebrows... by Roger+W+Moore · · Score: 1

      I was responding to the claim that because no charge flows in part of the circuit no electrical current can flow. This is not correct because you can have a charge build up which creates a reverse potential as was known pre-Maxwell.

      You also don't get the Maxwell equations correct. Instead of "mag-flux" you should have "magnetic field"(=B) and "e-flux" should be "electric displacement field"(=D). A magnetic flux is the magnetic field multiplied by an area and typically denoted using a capital phi. Also "div D" is equal to the electric charge density and the differentials are partial not full ones as you indicate.

    94. Re:Raised eyebrows... by Antique+Geekmeister · · Score: 1

      The actual article makes interesting sense. The write-up for slashdot, and the article cited in the Slashdot editorial, are awful and neglect the substance of the article. I'm embarassed at not having found the original article, which is in fact interesting.

      The "nerves use sound, not electricity" simplification is overstated and sensationalist: I'm embarassed at having taken it seriously.

    95. Re:Raised eyebrows... by andersa · · Score: 1

      IAAP and all I can say is that Andrew D. Jackson taught me quantum mechanics. You can trust me when I say that when it comes to thermal and quantum physics, the guy knows what he is talking about.

    96. Re:Raised eyebrows... by Antique+Geekmeister · · Score: 1

      Defibrillators transmit *current*, not voltage. Voltage is merely potential energy difference: curent is the charge flowing.

      It actually makes a difference when designing all kinds of circuitry: if you're unfamilar enough with basic electronics and physics, just trust me on this.

    97. Re:Raised eyebrows... by SeaFox · · Score: 1

      As another neuroscientist, I would urge you to keep an open mind.

      Is this an example of the fabled neuroscientist humor?

      No, I think this would be neurosurgeon humor.
    98. Re:Raised eyebrows... by Hatta · · Score: 1

      The misconception that the brain is full of little conductors, and that its operation is just like a computer, with electrical voltages and organic logic gates giving rise to "thoughts" is dear to the common mind. This misconception is responsible for the glamour exercised by one of the great follies of the age: the notion that we are in an essential and important way like computers, and that computers could be made to be--in some deeply significant way--like us.

      You seem to have the misconception that you need wires and transistors to do computation. Computation is a universal phenomenon. Computation can indeed be done with ion flows, or as we've seen in recent weeks on /. water and tubes, or even dominoes. The laws of physics are fundamentally algorithms, and therefore so are we. Turing tells us that any sufficiently complex computer is in an essential and important way like any other computer. In principle any algorithm that runs on one computer can run on any other. And so our computers can indeed be made to be significantly like us, by emulating us. Of course the technological problems inherent in that are prohibitive, but that's not the point.

      --
      Give me Classic Slashdot or give me death!
    99. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Besides, if you could prove this beyond reasonable doubt, you should and would send the paper to Nature. My favourite tabloid!
    100. Re:Raised eyebrows... by Floody · · Score: 2, Informative

      Absolutely incorrect. There is a reason that 'c' is called the "speed of light in vacuo". That reason is because a vacuum is the place where EM radiation travels that fast. In different media there is no requirement that the speed be this great. Indeed if you buy coax cable you will find that the rated signal speed is ~60-70% of 'c' although you can get special air-core cables with speeds of 80-90% 'c'. Clearly on a coax cable the signal is being transmitted by the EM field. Indeed there is a form of radiation, called Cherenkov, that is emitted by particles travelling faster than the speed of light in the local medium.


      No. You're talking about observed speed in a medium, not about 'c' (the absolute speed of light). The observed speed in medium being less than c is a result of charge interaction between matter and the EM wave (or polaritons from the QM perspective). "Light" (photons in QM) travel at c. Period.

    101. Re:Raised eyebrows... by mako1138 · · Score: 1

      May I point out that chemistry is applied physics? In a simple redox reaction, electric charge and potential energy are the things to think about.

      And regarding your first paragraph, you should study transmission lines fiercely before making strange arguments.

    102. Re:Raised eyebrows... by dsanfte · · Score: 1

      It's all very hard to visualize at first.


      Yes, apparently. People come to Slashdot, post comments under science stories, and don't even know the definition of a standing wave, phase vs group velocity, wave vs particle velocity, etc... It's really disheartening.
      --
      occultae nullus est respectus musicae - originally a Greek proverb
    103. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      IAACNSB (I am a computational neuro-scientist, booyah!) Neurons maintain (primarily by means of ATP driven pumps) an electrical gradient across their membrane which provides the driving force for ionic current into and out of the cell. The magnitude of this current, and net flux, is a function of conductances through voltage sensitive ion channels (and some leak channels as well). Action potentials, i.e. the presumptive signaling event, propagate as ionic current flow across the membrane moves a spatial region of depolarization, by opening voltage sensitive ion channels, progressively along the length of the axon (refractory period means that propagation is in one direction). When the region of depolarization reaches the synapse, calcium influx causes vesicles of neurotransmitters to dock with the membrane and dump their contents into the synaptic cleft where they bind with post-synaptic receptors which start depolarization in the dendritic tree. Does this mean that the communicate with EM fields? If it makes you happy to think so, then sure. If not, then no. But it is not a form of sound. I think these guys read a little bit too much into the silent synapse phenomenon.

    104. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      > IANANS, but the nerve impulses are electrochemical impulses

      There's no such thing as an "electrochemical impulse," the system is called "electrochemical" because it transmits both electrically and chemically. There isn't a third "in-between" mechanism, there's just the combination of the two.

    105. Re:Raised eyebrows... by thrawn_aj · · Score: 1

      Hmm, I misunderstood your comment. You do have a valid point. Is it known if mammals, insects and reptiles all have the same neural mechanism. I see mo remember that cold blooded cratures get sluggish in cool weather (the desert lizard thing whose name escapes my mind). Perhaps the sluggishness is not just a metabolic response but also a neural one. I know, long shot, and I don't know why I'm staunchly supporting the article (lol) but I would think it still hinges on whether different organisms have different tolerances as far as temperature regulation goes.

    106. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      Giant squid axon = a really big nerve in a squid. Not a nerve in a giant squid. A giant axon in a normal squid. Pretty minor detail but it seems to confuse WAY too many people to not be mentioned.

    107. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      A maverick neurologist - just the person I'm looking for. Is there any insight you can offer into a mechanism for a transmission speed of about one foot per day in humans? My best guess is that it's a cell-to-cell mode of communication that possibly pre-dates the evolution of the central nervous system.

      What I've observed is the fairly common "allergic reaction" to elastoplast bandages. The odd thing is that the reactions did not all occur at the same time, even though the bandages were all the same size and all applied at the same time. Rather, the timing of their onset corresponded to a communication speed of about one foot per day from the point of tramma.

      Thanks,
      Morrie

    108. Re:Raised eyebrows... by Ichoran · · Score: 1

      Electrical conduction in neurons is dependent on ion channels. Ion channels sit in the membrane and are dependent on its properties. If anaesthetics change those properties, certain classes of ion channels may not work particularly well. Some anaesthetics may interact directly with ion channels; some may act indirectly by changing lipid properties. I'm not seeing a huge problem here for the existing theory. In fact, I'm not seeing any problem.

      The whole "sound" thing seems like poorly supported speculation to solve in a complex and finely-tuned manner a problem which already has a simple solution.

      (Yes, I'm yet another neuroscientist.)

    109. Re:Raised eyebrows... by AxelBoldt · · Score: 1

      I'm not seeing a huge problem here for the existing theory.
      The huge problem is that after more than 100 years you still cannot explain the fundamental law of anesthetics, Overton-Meyer. Anesthetics following this law, which is the vast majority of them, cannot act by binding to proteins; they clearly act by dissolving in the membrane and changing its properties. How or why does dissolving diverse substances such as xenon, nitrous oxide, ether, ethanol or thiomethoxyflurane in the membrane affect ion channels in exactly the same way? The authors of the soliton model have a quantitative explanation: dissolving of anything lowers the membrane's melting point, which prevents solitons from passing through.

      (Yes, I'm yet another neuroscientist.)
      Then you must be aware of the experiments showing that the axon's membrane temporarily thickens and exerts a force, and that its temperature temporarily increases and then decreases as the action potential travels through. This is nicely consistent with the soliton model. How does HH theory explain this? The fact that the temperature decrease is inconsistent with HH was already acknowledged by HH themselves. Charges passing through a resistor always create heat and never remove it.
    110. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      IUAFNTEIPC (I use acronyms for no reason then explain in parenthetical comments) and I believe electricity was sent by the Devil to test us.

    111. Re:Raised eyebrows... by Ceriel+Nosforit · · Score: 1

      c is some 1.5 million times faster than the speed at which neural signal propagate.

      I believe this fact is sufficient for determining if I'm correct or not.

      --
      All rites reversed 2010
    112. Re:Raised eyebrows... by Ceriel+Nosforit · · Score: 1

      In a transmission line stray electrons mediate the EM force through their displacement. In a neuron, entire atoms move.

      I think this means a neuron isn't a transmission line.

      --
      All rites reversed 2010
    113. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      > c is some 1.5 million times faster than the speed at which neural signal propagate.
      > I believe this fact is sufficient for determining if I'm correct or not.

      No, it isn't, because the speed of the current is only relevant within a single neuron. Neurons transmit signals to each other chemically.

    114. Re:Raised eyebrows... by pclminion · · Score: 1

      I'm not sure if you're being sarcastic or not. Anyway, I'm not saying "God damn, people are stupid," I'm just saying a lot of people have a hard time visualizing what actually happens when electrical current flows. That doesn't make them stupid, but it does hinder an accurate understanding.

      And at least for the purposes of understanding electrical current in a conductor, the bouncing-balls view of electrons is just as valid and explanatory as the quantum version.

    115. Re:Raised eyebrows... by lukesl · · Score: 1

      The mechanism is not exactly the same, but it's close enough. However, when people think about action potentials, they have to think about how they evolved in simpler organisms, etc. Insects definitely have action potentials, and they actually are much better at tolerating differences in body temperature (not environmental temperature) than mammals are.

    116. Re:Raised eyebrows... by jlowery · · Score: 1

      The Journal of Dental research would disagree with you, for one:

      http://jdr.iadrjournals.org/cgi/content/abstract/2 7/3/336

      --
      If you post it, they will read.
    117. Re:Raised eyebrows... by Anonymous Coward · · Score: 0

      > The Journal of Dental research would disagree with you, for one:

      A poor choice of wording. They don't define what an "electrochemical impulse" is, and the article seems to be talking about the transmission of electrical stimuli from the surface of a tooth to the nerves in the pulp. This is still a combination of electrical and chemical impulses, not something in between.

      Interesting that you had to Google back to 1948 to find an example!

    118. Re:Raised eyebrows... by Ichoran · · Score: 1

      You didn't actually read what I wrote, did you? Dissolving of anything changes membrane properties. Changed membrane properties can affect ion channels. If there is good evidence that anaesthetics do *not* change ion channel properties, then there might be a reason to think about solitons.

      I'm not aware of the experiments showing membrane thickening. Please provide a reference. Likewise with the temperature decrease. Both of these sound very difficult to do correctly.

      Also, insects run around just fine when switched between 15C and 30C (ever seen ants running on a stove?). That doesn't bode well for theories that require a temperature-sensitive phase transition to get action potential propagation.

    119. Re:Raised eyebrows... by Roger+W+Moore · · Score: 1

      The observed speed in medium being less than c is a result of charge interaction between matter and the EM wave (or polaritons from the QM perspective). "Light" (photons in QM) travel at c. Period.

      These two statements are self contradictory: photons are an EM wave. In a material the photons interact with the EM fields and so do not propagate at te same speed as they would in vacuo.

    120. Re:Raised eyebrows... by Roger+W+Moore · · Score: 1

      No, this fact merely establishes that nerve signal are not transmitted by photons in a vacuum. It does not establish whether the signal is transmitted by electrical or chemical means, or indeed by a combination of the two.

    121. Re:Raised eyebrows... by mako1138 · · Score: 1

      I was (obliquely) hinting at flaws in your reasoning. You shouldn't make strange blanket statements that lead onto paths which end up at wrong answers.

      Aside from mass, a potassium ion carries the same amount of charge as an electron (though opposite, of course). The rebuttal to your original conclusion is simply:

      j = qv

      There are charges moving, so there is a current. It's a current that results from chemical processes, of course, but to deny that it is a current is inane.

  3. Shh by flyingfsck · · Score: 1

    That may explain tinnitis, but it doesn't explain why nerves react to electricity.

    --
    Excuse me, but please get off my Pennisetum Clandestinum, eh!
    1. Re:Shh by rnicey · · Score: 1

      Muscles react to electricity, but I was thinking along the same lines.

    2. Re:Shh by Joebert · · Score: 4, Funny

      Maybe, but it sure explains how my mother-in-law gets on my damn nerves every time she opens her mouth.

      --
      Wanna fight ? Bend over, stick your head up your ass, and fight for air.
    3. Re:Shh by Kelson · · Score: 1

      Similarly, I was wondering how this theory accounts for water intoxication.

    4. Re:Shh by Tragek · · Score: 1

      Man. If they showed me just that, I'd let them publish.

    5. Re:Shh by Anonymous Coward · · Score: 0

      Ahhh, this will explain the "Brown note" and the uncontrollable bowels.

    6. Re:Shh by cheater512 · · Score: 1

      Yeah but nerves do too. One can say that muscles react to electricity *because* nerves do.

    7. Re:Shh by Anonymous Coward · · Score: 0

      Everyone knows that water travels faster under water. If you put too much water in your body the nerve impulses travel too fast overwhelming the entire system and you die. Q.E.D.

    8. Re:Shh by eugene+ts+wong · · Score: 1

      I feel vindicated after reading the article summary and your post. I keep telling people that when I cough, I can feel the sound in my hand, but they won't believe me.

      I can cough. I feel something in my hand. If anybody has a better theory, then say so, but the onus is on the person disagreeing to provide evidence.

    9. Re:Shh by Anonymous Coward · · Score: 0

      You feel the pressure wave you generate with your cough.
      The eletro-chemical nerves lets your brain know that you feel it. Duh :)

    10. Re:Shh by Anonymous Coward · · Score: 0
      That may explain tinnitis, but it doesn't explain why nerves react to electricity.

      Maybe they don't -- maybe these guys think that Galvani's experiment with dead, detached frog legs worked because he secretly yelled at them, in addition to the documented application of electricity.

    11. Re:Shh by eugene+ts+wong · · Score: 1

      :^) Yeah, I know. I was just kidding around and trying out some humour. :^)

  4. Most redundant summary ever by Anonymous Coward · · Score: 0

    Including the title, this summary repeats the same information FOUR times. Come on, we're not that stupid!

  5. Might be mistaken... by Nemus · · Score: 3, Interesting

    I am currently in an Intro to Neuroscience class atm, but this sounds a bit...off. I am, obviously, not a scientist, but it seems to me that 1.)neurons and their associated structures do not have the physiological equipment necessary to produce sound, and 2.)Considering that the vast majority of passive and active scanning procedures specifically monitor or stimulate electrical activity in the brain, this seems a wee bit kooky. But, as stated, I ain't a scientist. Sage wisdom, folks?

    --
    Mod Points: Helping you keep your opinion to yourself.
    1. Re:Might be mistaken... by Anonymous Coward · · Score: 0

      1.) "everything known to man" produces sound

      2.) the thing to keep in mind here is that there is no real boundry between electricity and sound

    2. Re:Might be mistaken... by Anonymous Coward · · Score: 0

      you should read the FA .. and this : http://en.wikipedia.org/wiki/Soliton

      hope this helps..

  6. What a bad summary. by Wilson_6500 · · Score: 2, Insightful

    Is it just me, or did the summary say the same thing in three slightly different ways?

    1. Re:What a bad summary. by SoapDish · · Score: 2

      Close, but the third time there was no mention of sound.

      Nerves do not transmit by electricity (so current teaching is false): 3 times
      Nerves actually transmit by sound: 2 times

    2. Re:What a bad summary. by heinousjay · · Score: 1

      Thank you for mentioning it. I was scratching a hole in my head wondering just how far sideways I'd tilted.

      --
      Slashdot - where whining about luck is the new way to make the world you want.
    3. Re:What a bad summary. by boer · · Score: 1

      No, I noticed the same thing. The summary is repeating itself as you and I concluded. The unnecessary way of stating the alleged fact again ang again in the summary is therefore quite obvious to you and me.

      --
      (This sig intentionally left blank)
    4. Re:What a bad summary. by cybereal · · Score: 1

      Clearly they are invoking the art of The Seed of Doubt http://imdb.com/title/tt0240900/

      //Devon Sawa unavailable for comment

      --
      I read the script, and I think it would help my character's motivation if he was on fire. -Bender
    5. Re:What a bad summary. by The+Living+Fractal · · Score: 1

      Tell 'em what yer gonna tell em. Tell 'em. Then tell 'em what you told em.

      TLF

      --
      I do not respond to cowards. Especially anonymous ones.
  7. Load of crap by DrRevotron · · Score: 0

    This essentially flies in the face of proven medical cases in which ENS (electrical nerve stimulation) has treated symptoms such as clinical depression and eplilepsy. What a load of crap. Now, I'm no doctor, but this flies in the face of basic medicine.

  8. Uh. by Anonymous Coward · · Score: 3, Insightful

    Other scientists say, "These scientists are idiots."

    I'm so tired of hearing the press use "scientists say" as a legitimizing opener. If you believe something because "scientists" say so, you are probably not a scientist. If you were, you would be forced to know many scientists who are idiots; scientists who no one should listen to.

    Peer reviewed and agreed upon usually means good science. The CBC saying, "scientists say" means squatcum.

    1. Re:Uh. by omeomi · · Score: 2, Interesting

      I'm so tired of hearing the press use "scientists say" as a legitimizing opener.

      Next up? "Scientists say light bulbs use sound, not electricity"

      If you believe something because "scientists" say so, you are probably not a scientist

      You're probably a politician...assuming the scientists in question are ones who work for the people who give you money...

    2. Re:Uh. by Zombywuf · · Score: 1

      Even more annoying is the anthropomorphising of science. Statements like, "Science says ...," "Science does ...," really piss me off.

      --
      If you can read this you've gone too far.
  9. Bwha? by lazybratsche · · Score: 5, Insightful

    How do they explain all of the electrical measurements of nerve cells? We have measured voltages and currents. We know that these are dependent on certain protein channels, and salt concentrations. If impulses are actually the result of "solitons", how can they explain half a century worth of neurobiology? One wild guess, based on a minor inconsistency (if it even exists as they believe) needs a hell of a lot more evidence before they should be taken seriously.

    Extraordinary claims require extraordinary evidence.

    1. Re:Bwha? by Anonymous Coward · · Score: 0

      How do they explain all of the electrical measurements of nerve cells? We have measured voltages and currents. We know that these are dependent on certain protein channels, and salt concentrations. If impulses are actually the result of "solitons", how can they explain half a century worth of neurobiology? One wild guess, based on a minor inconsistency (if it even exists as they believe) needs a hell of a lot more evidence before they should be taken seriously.

      Extraordinary claims require extraordinary evidence. There can only be one explanation. Mechanical wave theory and electrical wave theory can be united! Give me my Nobel Prize!

      Um, of course equating the 1/v^2 term in the wave equation may be sort of difficult. I suggest using a super rigid ether for electromagnetic waves that magically loses all of its rigidity for mechanical waves.
    2. Re:Bwha? by drmerope · · Score: 1

      Well the theory isn't that the electrical changes don't happen; it's that the electrical changes we detect are related to the establishment of a sufficiently solid channel.

      i.e., the electrical pulses are part of the process of communication not an encoding of information itself.

    3. Re:Bwha? by The+Bungi · · Score: 1

      No one has successfully proved that those impulses are the communication. I think they're merely part of something more complex.

    4. Re:Bwha? by UbuntuDupe · · Score: 3, Funny

      "The CBC is reporting that a team of Danish scientists are claiming that telephone signals are transmitted by sound and not electricity. 'The common view that telephone wires transmit information through electricity is wrong and that they really transmit sound, according to a team of Danish scientists. The Copenhagen University researchers argue that telecom textbooks that say telephones relay electrical impulses from the source to the destination are incorrect.'"

    5. Re:Bwha? by ScrewMaster · · Score: 1

      Extraordinary claims require extraordinary evidence.

      Indeed. I think we should assemble a league of extraordinary gentlemen to look into it for us.

      --
      The higher the technology, the sharper that two-edged sword.
  10. Conspiracy theory alert: by Glowing+Fish · · Score: 5, Funny

    Time to replace all your tinfoil helmets with a pair of ear plugs.

    --
    Hopefully I didn't put any [] around my words.
    1. Re:Conspiracy theory alert: by Seumas · · Score: 1

      I have some friends who are married and from what I have observed, this whole "nerves / sound" thing is dead on.

  11. Will you guys quiet down! by RyanFenton · · Score: 5, Funny

    "Hey - will you guys quiet down? I can barely hear myself think!"

    Ryan Fenton

  12. Ooops by Edis+Krad · · Score: 1

    There goes down the Matrix now...

    1. Re:Ooops by Frumious+Wombat · · Score: 1

      It'll still work, you'll just have headphones, instead of big electrical jacks. Just hope the robots don't find out that Barry Manilow produces the most energy.

      --
      the more accurate the calculations became, the more the concepts tended to vanish into thin air. R. S. Mulliken
  13. TFA is completely innacurate by lazybratsche · · Score: 5, Informative

    On further review, it seems that the CBC article is total crap, but that the original paper isn't that far off the deep end. I admit that I don't know enough to really follow or critique the research, but it doesn't seem to be the crackpot theory that TFA implies. Nowhere, for example, does that paper say that nerves don't use electricity. In fact, the paper refers to "solitons" as a piezo-electric effect. They are merely proposing a new mechanism on top of previous theories, not trying to completely throw out all neuroscience to date.

    To recap: Completely bogus headline, based on a completely bogus bit of popular science reporting, which itself is based on a possibly intriguing (but tentative) bit of original research. Nothing to see here.

    1. Re:TFA is completely innacurate by Anonymous Coward · · Score: 0

      Yeah, the CBC title and summary are simply egregious. I'd like to know how anybody could possible deduce the CBC article from what the original biophysj artical says. It pretty much makes all of the arguments in this forum and every other forum that picks up this crap, irrelevant.

    2. Re:TFA is completely innacurate by myc · · Score: 5, Interesting

      BTW, IAANS (I am a neuroscientist). Here is another link to their earlier research on this. While PNAS is certainly a reputable journal, I made some interesting observations while reading their paper:

      (1) It's very physics- and modeling-heavy. While I don't like to generalize, my impression has always been that physicists are not very good biologists. I've been to many a "cross-disciplinary" seminars where physicists try to model biological processes, and inevitably they make very little biological sense.

      (2) They cite mostly old papers from the literature (1960s) that point out deficiencies in the Hudgkin-Huxley model (although it's true that the HH model of action potential propagation may have become dogmatic).

      (3) It was published via track I in PNAS, wherein a Member of the National Academy of Sciences can directly accept the paper for publication, bypassing peer review. The purpose of this mechanism is so that controversial works have a chance to be published; historically, it has been used to dole out favors and/or to publish crackpot theories.

      Ultimately, while what they are proposing is not as crazy as TFA makes it out to be, the paper sounds to me that they are trying to make a mountain out of a molehill. Neuroscientists today have a very detailed understanding of how axonal neurotransmission works. The authors claim that the solitons (sound waves) in their model explain how nerve propagation in myelinated axons can be much faster than in equivalent non-myelinated axons, but again, neuroscientists are fairly sure they understand myelination in the context of the HH model. Even if axons go through soliton mediated pulses on the membrane that are in phase with action potentials (which is what they claim to observe), I seriously doubt that it has any physiological relevance, since just about everything neurons can do can be explained by ion flux through channels.

      --
      NO CARRIER
    3. Re:TFA is completely innacurate by kingsean · · Score: 0, Redundant

      I ... uh ... yeah. Ion Flux. Channels. That's basically what I was going to go with, but you beat me to it. So ahhhhhh, Well done to both of us!

    4. Re:TFA is completely innacurate by abes · · Score: 5, Informative
      Just to add to this, for people who are confused:

      (1) Hodgkin and Huxley (1952) postulated the existence of transmembrane proteins that allowed conductance of ions in and out of the cell. They showed, using a giant squid axon, that action potentials are composed of a sodium current and a potassium current. While they had no way to directly observe the channels that allowed these currents to flow, using curve fitting, they worked out the general dynamics of these channels.

      (2) Sakmann and Neher (1976) showed the existence of these channels by developing the whole-cell patch clamp technique. Single channels have been observed and characterized using this method (and employed by many labs).

      (3) The term 'tranmission' is sometimes used in a confusing manner in neuroscience. In this case, as pointed out by the parent, transmission is down the axon of a single cell. Mylen sheaths can form around the axons of cells in order to speed up transmission. This can also occur by making the axon diameter wider. One interesting difference between vertebrates and invertebrates is that appearance of the mylen sheath with the advent of the backbone. This allows for cells to take up less space (so more can be packed into a given volume).

      Another form of transmission of signal is between cells. This is usually done by chemical synapses. Chemical synapses work by the presynaptic cell releasing chemical into the synapse, the chemical ligand binding to receptors on the postsynaptic cell, and causing either an ionic flux (ionotopic channels) or a chemical cascade (metatrobic channels).

      Somewhat recently there has also been discovered electrical synapses in the mammalian brain. These seem to be between inhibitory cells of the same type.

    5. Re:TFA is completely innacurate by Anonymous Coward · · Score: 0

      Isn't CBC the same organization that last week hosted a pile of pig offal disguised as a story on breaking the speed of light?

      It's one of the sites that I had come to assume, long before encountering its pumped up indecipherable tripe on Slashdot, was a complete waste of time.

      deflate: http://images.slashdot.org/hc/04/c3365c1b3923.jpg

    6. Re:TFA is completely innacurate by Anonymous Coward · · Score: 0

      While I don't like to generalize, my impression has always been that physicists are not very good biologists.

      Oh yeah? Oh yeah??? Well, in my experience, biologists are pretty crappy at physics! Right back at ya!!!

    7. Re:TFA is completely innacurate by Jm_aus · · Score: 1

      IAAA (I am an anesthesiologist) and these guys are resurrecting aspects of a theory from over 100 years ago (Overton's study was published in 1901 and Meyer's in 1899) which fits very neatly with some data for volatile anesthetic agents and which is completely inconsistent with other observed data: The lipid partition coefficients of many anesthetic agents do appear to be closely related to their potency independent of structure (as the paper says), but there are other agents which are similar to volatile anesthetics in lipid partition coefficient and structure and which have no anesthetic activity (such as 1,2-dichlorohexafluorobutane) The reversibility of anesthetic action by pressure which they mention is indeed observed, but the effect of temperature on lipid fluidity which they also mention is completely different from the observed change in anesthetic requirement with change in temperature in mammals. For a much better description of the state of understanding of the action of anesthetic agents, I suggest this paper: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=p ubmed&cmd=Retrieve&list_uids=12933393

    8. Re:TFA is completely innacurate by SlayerDave · · Score: 1

      Just a point of clarification: H&H used a squid giant axon, not a giant squid axon. Common misconception.

    9. Re:TFA is completely innacurate by FlyingGuy · · Score: 1

      Not to worry, its all just tubes.

      --
      Hey KID! Yeah you, get the fuck off my lawn!
    10. Re:TFA is completely innacurate by abes · · Score: 1

      Yup, typo on my part. Though, I will admit, that had me confused for quite some time, as Giant squids weren't generally available to do experiments on.

      For the curious, the axon is 'giant' because it needs to conduct signal from one end of the squid to the other. Due to speed constraints, and leakage, this means the diameter of the axon needs to fairly big (no mylen sheath). Because of this, the axon was big enough to insert electrodes by hand.

    11. Re:TFA is completely innacurate by backwardMechanic · · Score: 1

      To reply to point one, don't forget Crick and Watson. Maybe you've heard of them? They did some rather famous work while at the Cavendish lab in Cambridge (England). Yeah, that's a physics lab. Oh, yes, IAAP, who's studied a bit of neuroscience. Smug mode engaged.

    12. Re:TFA is completely innacurate by Legion303 · · Score: 1

      I don't believe that's the paper referred to in TFA. The in-depth paper I'm reading from Heimburg and Jackson is called "On the action potential as a propagating density pulse and the role of anesthetics."

  14. am I making since or.... by lord3nd3r · · Score: 1

    okay, I can understand what they are saying but then why is it when your body is electrified, your nerves loose the (signal) from your brain and you convulse? If your nerves rely on sound and not on electricity then wouldn't there be no (nervous) reaction if and or when electricity goes through your body?

    --
    g0t b33r?
    1. Re:am I making since or.... by ColaMan · · Score: 1

      Never mind that, what about people getting ultrasounds? Expectant mothers getting scanned would be all over the place.
      Once, when I tore the ligaments in my hand, they went over the area with an ultrasonic gadget that was seriously ultra - it was in the 2 to 3 MHz range.

      Surely either of those would have excited or swept past the frequency that nerves allegedly transmit at?

      --

      You are in a twisty maze of processor lines, all alike.
      There is a lot of hype here.
    2. Re:am I making since or.... by lord3nd3r · · Score: 1

      spanking of which... were you aware that if you use a certain frequency or vibration, you can grow brand new teeth?

      --
      g0t b33r?
    3. Re:am I making since or.... by backwardMechanic · · Score: 1

      Conducting all that current will generate a fair bit of heat. Maybe that upsets the delicate thermal balance of the propagation process?

    4. Re:am I making since or.... by Anonymous Coward · · Score: 0

      Ever been to a rave, it's kinda like that ...

  15. Does this mean by Anonymous Coward · · Score: 0

    that I can drown out my pain by cranking up Motorhead?

  16. so.. by Anonymous Coward · · Score: 0

    maybe the physicists should stick to physics, and leave the chemistry and biology to the chemists and biologists.

  17. An article by one of the members of the res. group by Inf0phreak · · Score: 1
    They wrote an article on their research in the previous edition of Gamma (the quarterly (IIRC) thingie about physics that's published at the Niels Bohr Institute at the University of Copenhagen (help me out here Danish physics students... I'm not too sure on the specifics of who is responsible and what its scope is))

    Anyway, you can read that article in its entirety here: http://www.gamma.nbi.dk/Galleri/gamma143/nerves.pd f

    IANANS (guess...) but I do find it very agreeable that it is odd that strength of an aneastaesia (yeah, it's misspelled) is proportional to its solubility in lipids if the inner workings of nerves are driven by electricity.

    --
    ________
    Entranced by anime since late summer 2001 and loving it ^_^
  18. Like the Internet by Digital+Pizza · · Score: 2, Insightful

    It's a series of tubes.

    --
    We apologize for the inconvenience.
    1. Re:Like the Internet by LodCrappo · · Score: 1

      And if you don't understand those tubes can be filled and if they are filled, when you put your message in, it gets in line and it's going to be delayed by anyone that puts into that tube enormous amounts of material, enormous amounts of material...

      --
      -Lod
    2. Re:Like the Internet by StarfishOne · · Score: 1

      Aahhh, that explains why some people are so dense! :D

  19. So the druggies of the 60's were correct... by physicsboy500 · · Score: 0

    They really could feel the music!

    --
    The original generic sig.
  20. It's like a concert hall in here by Profane+MuthaFucka · · Score: 0

    The theory explains perfectly why a whore's pussy feels SOOOO damn good. Good acoustics.

    --
    Fascism trolls keeping me up every night. When I starts a preachin', he HITS ME WITH HIS REICH!
  21. Well... by Anonymous Coward · · Score: 0

    ...that would certainly explain the voices.

    1. Re:Well... by Gulthek · · Score: 1

      2) Science is guided by intuition and obviousness. It's silly to say that metric boatloads of evidence do not "prove in any way" that to which they obviously point. You cannot "prove in any way" that you exist, that you are not merely the representation of a very elaborate bit of tinkering with my brain, which, by the way, may also not exist. It is enormously more likely, given the evidence, that you actually do exist.


      Surely you're joking [title] chaboud.

      Science is guided by the scientific method. Observe, hypothesize, test, explain.

      Also:

      Merely because electrial triggers work, doesn't mean that's how our nerves were meant to operate. If I were a brain surgeon I could make your muscles "work" by pushing on your brain.
    2. Re:Well... by Anonymous Coward · · Score: 1, Insightful

      Science is guided by intuition and obviousness.

      Guided by, yes. Science is, however, a method of experimentation and revission. That said, intuition tells us that object that are pushed come to a stop, and return to their "natural state" of rest... For centeries we KNEW this to be fact.

      We knew that heavier objects fall faster than light objects, it's just intuitive that they do, so it must be the case. We never tried, and we KNEW this as fact.

      We thought it obvious that if the earth was moving, there would be wind and that the pigeons would fall off their perches. The earth must be static, fixed in place at the center of the universe, with the stars painted on glass spheres arround us because it's just obviously true. We KNEW this as fact.

      Science taught us, don't assume because of obviousness and intution; instead make a guess and test it out. Galiello dropped many an item off the roof of buildings and found that weight of an object isn't important to how fast it falls. In fact, he realized that objects fell with a constantly increasing speed toward the earth. He discovered what everyone attributes to Newton, Gravity.

      Newton, later found that objects don't "tend to the natural state" but rather remain in a state indefinatly untill acted on by an object or force. He quantified that constant rate of change and developed calculus comming from one direction (while some German guy was doing the same thing in Germany or somewhere like that :) ).

      Coprenicus, Kepler, Galilleo came to realize that the Earth is not flat. That it isn't the center of the unverse, and that all the planets in the solar system orbit the sun sweeping out equal distance in equal time.

      It's silly to say that metric boatloads of evidence do not "prove in any way" that to which they obviously point.

      I don't see metric boatloads, VW bugs, bread boxes or anyother evidence that "proves" anything in this matter untill more experiments are carried out.

      You cannot "prove in any way" that you exist,

      This part, I can. "Cogito, ergo sum. QED." I can't prove, however, that you exist.
      Everything in the world we know as fact can be placed into this sentence and it makes logical sense:
      "It is not the case that X; however, I am having all of the thoughts, feelings and experinces as if X"
      Except for ones of a certian nature, that being "I think", "I feel" or "I am" statments.
      Let's try it.
      "It is not the case that I exist; however, I am having all of the thoughts, feelings and experinces as if I exist."

      The problem: If I don't exist, then I can't be having all of the thoughts, feelings or experiences as if I did, because I would exsist to think, or feel, or experience.
      Which, in true Descarte fashion I have proved, "I think, therefore I am."
      Now, are you?

      that you are not merely the representation of a very elaborate bit of tinkering with my brain, which, by the way, may also not exist.

      I can't be a tinkering with your brain, because I exist, I just proved it. Now, my proof isn't valid in your mind, if you do indeed exsist which I can't prove directly; but, if you do exist, you can work through the logic above and logically prove you exist. There are even formal symbolic proofs if you like symbolic logic.

      Now, to prove your existance to me (or mine to you), Descarte would use God; which is a leap of faith that was exceptable and expected in the time he was writing. Realistically, I can't prove it to you or anyone other than me that I exsist; all I can do is offer you a choice to except that this world is real or let you search for some intrinsic truth of your own. Pragmatically, I chose to believe the world exsists, because if it didn't knowledge of anything outside myself would be impossible to obtain. In this regard, Locke's writings make sense. There is an external world, and there is our preception

  22. Re:An article by one of the members of the res. gr by myc · · Score: 1

    that's not strange at all, especially if you don't know the pharmacological target of an anesthetic. Many lipids are used as chemical second messengers. There are many membrane bound proteins that might be a target.

    --
    NO CARRIER
  23. Re:An article by one of the members of the res. gr by sessamoid · · Score: 2, Informative
    IANANS (guess...) but I do find it very agreeable that it is odd that strength of an aneastaesia (yeah, it's misspelled) is proportional to its solubility in lipids if the inner workings of nerves are driven by electricity.
    So you're willing to accept this on something as coincidental as the strength of a drug being proportional to its lipid-solubility? Wow.

    Every cell in your body is encapsulated by a cell membrane that is essentially two layers of lipids. It's not a real revelation that many drugs' effectiveness is enhanced by lipid-solubility.

    --
    "No, no, no. Don't tug on that. You never know what it might be attached to."
  24. Outside their field. by rahvin112 · · Score: 1

    Professional (or potential) Physicists producing research about biology saying nerves work on sound.

    Next thing you know some silly chemists from Utah will claim they discovered "cold" fusion by producing bubbles from metal rods.

    Well, maybe when we live in Bizzaro world.

    1. Re:Outside their field. by thrawn_aj · · Score: 1

      Professional (or potential) Physicists producing research about biology saying nerves work on sound. We have a segregationist here pholks :P. And by the way, they are biophysicists. Interdisciplinary scientists do exist today you know. Next thing you know, those darn chemists will be horning in on biological territory. After all, chemists have no business when it comes to enzymes and ummm proteins and .... oh wait :P
    2. Re:Outside their field. by Anonymous Coward · · Score: 0

      I hope the parent to this post isn't modded up. Here's a relevant quote by a famous physicist (uh-oh, he's out of his field making quotes too, isn't he?):

      "If our small minds, for some convenience, divide this glass of wine, this universe, into parts -- physics, biology, geology, astronomy, psychology, and so on -- remember that Nature does not know it!"
      - R.P. Feynman

  25. how this could make sense by Anonymous Coward · · Score: 0

    electrical impulses cause the nerve endings to vibrate.. these vibrations propagate out through the surrounding fluid. the neurotransmitters released ride the waves across the gap between nerve cells. these vibrations constitute sound..do i believe this.. no. but. whatever.

  26. Chalkboard, anyone? by EEBaum · · Score: 1

    This could explain the intense physical reaction to fingernails on a chalkboard. Hits just the right frequency, perhaps...

    --
    -- I prefer the term "karma escort."
  27. Truth by Anonymous Coward · · Score: 0

    Must be true. All the Brown Noise from this story made me crap my pants.

  28. If it's really sound that makes my muscles move... by Eric+Damron · · Score: 1

    then why don't my legs jerk when I fart?

    Just a question.

    --
    The race isn't always to the swift... but that's the way to bet!
  29. If that's the case... by teamhasnoi · · Score: 3, Funny

    What happens when you play those nerves backwards?

    You turn into Ozzy Osbourne?

    1. Re:If that's the case... by ghmh · · Score: 1

      What happens when you play those nerves backwards?

      You turn into Ozzy Osbourne?

      Which then begs the question - what happens if Ozzy Osbourne plays them backwards...?

  30. That explains why.... by kbox · · Score: 2, Funny

    ... I dance like an idiot to loud German trance music.
    It's not because I'm drunk, It's involuntary movements caused by the sound, Some "scientists" said so!

  31. It would explain the Brown Sound... by solios · · Score: 1

    From what I vaguely remember of my artskool audio class, Sound at wavelengths of 5hz and below are more than capable of disrupting human thought. 10hz being the South Park "brown sound," which will disrupt the bowels (see also Transmetropolitan, etc).

    1. Re:It would explain the Brown Sound... by Anonymous Coward · · Score: 0

      It really depends on amplitude. For example, if you stand in a small room front of a 5m X 5m panel generating 1Hz vibrations of an amplitude of only 10^-10 Tm could very easily disrupt your thoughts.

  32. I guess we'll have to throw out years of... by istartedi · · Score: 0

    ...EEG results... NOT! Oh, and experiments in biology going all the way back to that guy who put wires on dead frog legs and made them twitch, sorry don't feel like looking it up. Oh, and when I was a kid and I had the electronic project kit and made my thumb twitch with electricity. Or, anybody who's ever felt a shock. Yes. From now on, we'll do all of that by YELLING REALLY LOUD.

    And no, I didn't read TFA, but do I really have to? For once, I think not.

    --
    For all intensive purposes, "whom" is no longer a word. That begs the question, "who cares"?
  33. Mind control? by JimXugle · · Score: 5, Funny

    Imagine all the possibilities! You could make someone do something just by yelling at them loud enough!!

    --
    -jX

    Don't you just love politics? It's like a comedy of errors.
    1. Re:Mind control? by PrimordialSoup · · Score: 1

      Wife to Husband (yells): Take out Garbage, you Moron!!

      Husbands nerves gives the appropriate response of taking our the garbage...

    2. Re:Mind control? by SageMusings · · Score: 1

      These aren't the droids you're looking for...

      Move along...

      --
      -- Posted from my parent's basement
    3. Re:Mind control? by Joebert · · Score: 1
      Larry the cableguy just called to say

      I don't care who yare, that's +5 Funny right dere.
      --
      Wanna fight ? Bend over, stick your head up your ass, and fight for air.
    4. Re:Mind control? by Anonymous Coward · · Score: 0

      Imagine all the possibilities! You could make someone do something just by yelling at them loud enough!!

      Perhaps the phrase "Double the killer select all" explains why GWB went after Osama.

    5. Re:Mind control? by mqduck · · Score: 1

      Imagine all the possibilities! You could make someone do something just by yelling at them loud enough!!


      That's what Lieutenant L.T. Smash calls "superliminal."
      --
      Property is theft.
    6. Re:Mind control? by Lucek · · Score: 1

      Imagine it? Try it... Get married.

  34. Remember Einstein? by Anonymous Coward · · Score: 0

    Before 1914 we had it all figured out: Gravity, Electromagnetism, blackbody radiation...

    Heck, us humans have observed gravity and it's effects for millenia, while the underlying principle that drives it (Einstein's General Relativity) has only recently been even proposed.

    You are right about the evidence though.

  35. Do they mean Phonons? by Anonymous Coward · · Score: 0

    By sound, I think they mean "Phonons", which are the 'quanta' of sound, and have been seen to affect molecules on small scales. It may be a combination of ions, phonons, and voltage potentials that create nerve signals. As molecules change shape ( say ion pores ), especially in cell membranes, they could set up phonons in the cell surface, or internal scaffold proteins, and these could affect the behaviour of other pores.

  36. Don't agree with TFA by Anonymous Coward · · Score: 0

    While I fully agree that saying nerves transmit via electricity only is incorrect, I have a hard time viewing action potential propagation as sound in any way shape or form. It would be more correct to label it as electro chemical transmission. Neurons propagate action potentials down their axons with a really neat system of chemical gradients that result from differeing concentration of Sodium ion, potassium ion and chloride ion between the intercellular fluid and the extracellular fluid. Electricity can disrupt these charged ions as well as the voltage gated ion channels (i.e. changes in voltage open or close pathways in the cell membrane that allow the ions to diffuse along their concenttraion and charge gradients and the cell constantly uses an energy expending process, the Sodium Potassium pump, to create differences between intra and extracellular fluid) in the cell membrane which cause changes in the previous ions concentrations which (duh) is why shocking a frog's leg can make it move and why we measure all sorts of voltages. Google squid giant axon, action potentials, nernst equation, voltage clamp, nodes of ranvier, myelin, saltatory conduction, etc for some good information. Remember voltage is only a reading of the difference in charge between point A and point B. Volts aren't what kill you. Current is.

    Also once this action potential travels down the length of the axon it reaches a synapse, which then requires a chemical means of sending a message to the next neuron.

  37. Earplugs? by doit3d · · Score: 4, Funny

    Does this mean that the next time someone kicks me in the nads all I need are earplugs for the pain to go away?

    I don't think I will test that theory, I'll let someone else do it.

    --
    "This is America... where the will of the few outweigh the outrage of the many..." - Unknown
  38. Theory can co-exist with Hodgkin and Huxley by Anonymous Coward · · Score: 0

    This theory doesn't necessarily contradict Hodgkin and Huxley model. As a neuroscientist, you should surely know that H&H have developed their models based on giant squid nerve. The recordings you have done in the "classical manner" are also on large nerves.

    Their model would explain the narrow (myelinated) nerves (used to transmit pain), which are used to conduct pain. These nerves are much narrower than H&H nerve model, and the "classical" model has difficulty explaining the efficiency of transmission in such nerves.

  39. I had to check the calendar... by SmoothTom · · Score: 1

    After reading the article, I thought maybe I'd slipped up a bit and somehow missed a few weeks, but no, it's not April First...

    *I* want some of what *THEY* are smoking... :o)

    --Tomas

  40. You know... by glwtta · · Score: 2, Insightful

    Rephrasing the same statement three times is actually not the same thing as elaborating on it. Repeating something three times dos not provide more information. It's wrong to think that stating something three times over will make for a better summary.

    --
    sic transit gloria mundi
  41. The famous saying is fitting. by CrazyJim1 · · Score: 1

    Shutup, you're getting on my nerves.

  42. So how do... by RandySC · · Score: 1

    deaf people walk?

    --
    Organization: alphabetical, sometimes numerical or messy
  43. Watch this! by Anonymous Coward · · Score: 0
  44. Re:I agree, this is BS by posterlogo · · Score: 2, Insightful
    I have a biology Ph. D. as well, and with some great neuroscientists in my department doing some cool electrophysiology stuff, this article seems crackpot to me at best, and total bullshit at worst (i.e. they're just spinning it differently to get some publicity).


    To illustrate, his most compelling argument is this: "The physical laws of thermodynamics tell us that electrical impulses must produce heat as they travel along the nerve, but experiments find that no such heat is produced."


    This was when I thought he was full of shit. Any type of 'communication' requires some energy. The transduction of sound (molecules hitting one another in a propagating a pressure wave) also could produce heat in the thermodynamic argument. TFA is lacking on sufficient detail to look into this further.

  45. these people are nuts by oohshiny · · Score: 2, Informative

    The conduction of nerve impulses is understood at a detailed molecular level. There are numerous experiments that have observed everything from individual charges and ions traveling through channels and careful electrical modeling, to rationally designed anaesthetics that interact with specific molecules and targeted modifications of channels.

    Now, it's always a good idea to keep an open mind. But these people have presented no even remotely interesting evidence that we need a change in paradigms. They are simply nuts.

  46. Feh! I'm not wasting my mod points on this! by shoolz · · Score: 1

    Why do I only seem to get mod points on Friday evenings when poop like this populates the home page? I give up.

  47. So... by thrill12 · · Score: 5, Funny

    ...can we say officially that this part of slashdot has become a FANSCOS now (First Annual NeuroScientist Convention On Slashdot) ?

    --
    Slashdot: stuff for news, nerds that matter, matter for news, stuff that nerd
    1. Re:So... by Mad_Rain · · Score: 1

      Damn, I missed the announcement!

      I would like to subscribe to your newsletter....

      --
      "What do you think?" "I think 'What, do you think?!'"
    2. Re:So... by RealGrouchy · · Score: 1

      ...can we say officially that this part of slashdot has become a FANSCOS now (First Annual NeuroScientist Convention On Slashdot) ?

      Only if you're a neuroscientist, too.

      I'm don't really consider myself a neuroscientist, but I do hit random people on the head and record their reaction.

      - RG>
      --
      Hey pal, this isn't a pleasantforest, so don't waste my time with pleasantries!
  48. Re:If it's really sound that makes my muscles move by Anonymous Coward · · Score: 0
    then why don't my legs jerk when I fart?

    They don't???

    Mine always do. And my cheeks flap. Sometimes quite vigorously.

  49. It's true. Sound does it. by Neeth · · Score: 1

    One day after sleeping badly, an anatomist went to his frog laboratory and removed from a cage one frog with white spots on its back. He placed it on a table and drew a line just in front of the frog. "Jump frog, jump!" he shouted. The little critter jumped two feet forward. In his lab book, the anatomist scribbled, "Frog with four legs jumps two feet."

    Then, he surgically removed one leg of the frog and repeated the experiment. "Jump, jump!" To which, the frog leaped forward 1.5 feet. He wrote down, "Frog with three legs jumps 1.5 feet."

    Next, he removed a second leg. "Jump frog, jump!" The frog managed to jump a foot. He scribbled in his lab book, "Frog with two legs jumps one foot."

    Not stopping there, the anatomist removed yet another leg. "Jump, jump!" The poor frog somehow managed to move 0.5 feet forward. The scientist wrote, "Frog with one leg jumps 0.5 feet."

    Finally, he eliminated the last leg. "Jump, jump!" he shouted, encouraging forward progress for the frog. But despite all its efforts, the frog could not budge. "Jump frog, jump!" he cried again. It was no use; the frog would not response. The anatomist thought for a while and then wrote in his lab book, "Frog with no legs goes deaf."

    (joke shamelessy copied from this site)

    --
    Yes, I am the one with the legendary sig.
  50. Could be both? by rufusdufus · · Score: 1

    Its very possible that neurons communicate using both electrical signals and sound solitons (and who knows what else?). If you play around with genetic algorithms or supercompilers you see that optimal solutions to problems often use unexpected mechanisms that defy logical analysys. We should expect to see this sort of efficiency in real evolved systems too.

  51. Both are wrong. by Ihlosi · · Score: 1
    The Copenhagen University researchers argue that biology and medical textbooks that say nerves relay electrical impulses from the brain to the rest of the body are incorrect.



    A single nerve cell transmits information by having a depolarized zone travel down the axon, which is an electrochemical process.


    Information travels between nerve cells through synapses, which can either be chemical (using a neurotransmitter) or "electric" (electrochemical).



    So if these guys claim that biology and medical textbooks talk about electrical impulses, maybe they need to get some real textbooks first and non some pop-sci ones.

    1. Re:Both are wrong. by AxelBoldt · · Score: 1

      So if these guys claim that biology and medical textbooks talk about electrical impulses, maybe they need to get some real textbooks first
      The CBC summary is garbage. Much better articles are here and here.
  52. Secondary system by Frozen+Void · · Score: 1

    I believe brain has multiple systems to ensure the signals gets through or get reliably.
    Sound maybe one of them.Electricity another.The third one might be chemical pathway or radio frequency.
    Dismissing the idea,brain would have one point of failure,one big magnet and the nerve system is useless(not to mention the interference from the electric devices and wires).

  53. Nerve impulses=sound by Anna+Merikin · · Score: 1

    It's so loud in here "I can't hear myself think."

    And for all this time I thought that was just a figure of speech.

  54. Read the original before objecting. by zCyl · · Score: 3, Informative

    TFA sounds pretty crackpot to me. If they really had strong evidence for this it would be published in Nature, not Biophysical Journal.

    First, the Biophysical Journal is fairly respectable, and a much more appropriate place to publish work in this area. Second, the actual journal article in the Biophysical Journal does NOT say what the Slashdot and CBC titles say, so judging them on this basis is inappropriate. The article is an extension of a previously published model which shows that nerve signal propagation can be described as 100m/s piezo-electric soliton pulses, and it shows that these are dependent upon the phase transition temperatures for membranes.
  55. Time for a career change! by Kuroji · · Score: 1

    I always wanted to work as an electrician but I've been deathly afraid of, you know, accidentally touching a line and the electricity causing my muscles to contract and involuntarily clamping onto a naked wire. Glad to know that's a myth now! Wait, I still hate heights. Perhaps it's time for me to pursue a brave new career as a lightning rod!

  56. impossible!! by N3wsByt3 · · Score: 1

    What the...? Nerve impulses are transmitted by sound?! I can't believe my ears!

    --
    --- "To pee or not to pee, that is the question." ---
    1. Re:impossible!! by N3wsByt3 · · Score: 1

      You know...sound...ears...

      meh. Nevermind, probably wasn't as funny as I thought...

      --
      --- "To pee or not to pee, that is the question." ---
  57. Electro-mechanical coupling by srussia · · Score: 1

    It is entirely possible for ionic transfer to induce mechanical transformation within nerve cells, and in turn, for such movement to trigger ionic transfer. Remember these?

    --
    Set your phasers on "funky"!
  58. Funny :) by laplace_man · · Score: 1

    I'm sure I have at least 2 kA current from ankle to brains that can produce heat.So P=I^2*R=m*c*delta(T) right..So you suggest that heat from current in my nerves should be visible on thermal camera ??? Damn that stupid. Stick a needle in your nerve put a nice high gain amplifier ....no that sounds like torture...perhaps voltage coming out of the nerves is so high that you can measure it on the skin on some places. The answer for this people will come when they'll understand why we use transformers in power systems :))

  59. they do not say .. by Anonymous Coward · · Score: 0

    Reading the original article (link at CBC) the CBC story - to put it (very) mildly - takes liberties with the claims of the authors - their results concern the effects of anesthetics on membrane thermodynamics. They claim that anesthetics all act through the same mechanism (in its self quite a claim). They say that these (typically small membrane soluble) molecules change the thermodynamic properties of the membranes of neurons in such a manner as to prevent the proper operation of proteins, called ion channels, in the membrane that are necessary for the propagation of the electric impulses along the membrane.. no electric impulse no pain signal ..

  60. Why did the Galvani experiment work? by Metasquares · · Score: 1

    If it is sound, why did Galvani's experiments with electricity and frogs' legs work?

    1. Re:Why did the Galvani experiment work? by sweaterface · · Score: 1

      IANAL(ogician), but you are confusing necessary and sufficient conditions. Granting that passing an electric current down the proper nerve is *sufficient* for making a frog's legs twitch, that does not imply that passing an electric current down that nerve is *necessary* for making a frog's legs twitch.

    2. Re:Why did the Galvani experiment work? by Metasquares · · Score: 1

      If nerves used sound, I'd expect that an electrical current would not be *sufficient* to cause the legs to twitch, unless the current was somehow producing the appropriate sound (which is possible, but was not mentioned in the article).

      If nerves responded to both electricity and sound, it could be a sufficient condition but not a necessary one, but that wasn't the article's hypothesis.

    3. Re:Why did the Galvani experiment work? by sweaterface · · Score: 1

      Muscle action and nerve conduction are totally independent processes. No one is disputing the widely held belief that electrical impulses are responsible for muscle action. Thus, no one is disputing what makes a frog's legs twitch. What is being disputed is the mechanism by which signals are ordinarilly transmitted down nerve pathways - whether electrically or by sound waves. There is no reason to expect that a nerve could not conduct an electric current even if the natural method of impulse propagation is by sound waves. Moreover, Galvani's experiment supports, not undermines, the case that sound waves propagate nervous impulses. One of the claims that these researchers are making is that if nerve impulses were electrical impulses, then we would expect more heat than we are finding. Hook a frog up to a battery for a while and watch its legs twitch...then touch it, and you'll notice that it's warm.

  61. So does it mean that... by Deorus · · Score: 3, Funny

    My brain actually listens to what I see? How confusing...

  62. Sounds, Nerves and Migraines by thewiz · · Score: 1

    Well, if nerves really do communicate by sound that would explain why my head feels like someone is playing a thrash metal tune in it when I have a migraine.

    --
    If "disco" means "I learn" in Latin, does "discothèque" mean "I learn technology"?
  63. It's quite simple, really. by The_mad_linguist · · Score: 5, Insightful

    Insightful gives karma, funny doesn't.

    1. Re:It's quite simple, really. by mikiN · · Score: 0, Redundant

      And you think we all post stuff on Slashdot just for the karma?

      In Soviet Russia, Karma whores You!
      In Korea, only old people are karma whores.
      All your karma are belong to us!

      I don't need any karma. To post or not to post, that's the question...

      --
      The Hacker's Guide To The Kernel: Don't panic()!
    2. Re:It's quite simple, really. by Headcase88 · · Score: 1

      They should have an "hilarious" mod that gives karma, to be reserved for truly funny posts, to counter-act that sort of thing.

      --
      "When the atomic bomb goes off there's devastation...but when the atomic bong goes off there's celebraaaaation!"
  64. Music by Captian+Obias · · Score: 0

    So the music really does move your body.

  65. Questions Answered by ChronoFish · · Score: 1

    When I first read the I article snippet I thought, as much of the /.ers, that this was bogus. Then I did a search and found a better article - and in comments to that article I found the actual text from the researchers. http://www.citebase.org/fulltext?format=applicatio n%2Fpdf&identifier=oai%3AarXiv.org%3Aphysics%2F061 0117 I think you'll find that most of the concerns that the /. audience brings up are addressed. Thinking outside the box is hard - even for those of us who feel we are scientifically minded. -CF

  66. I doubt that! by ketilf · · Score: 1

    Having a bullshit filter is a good thing, and mine was in the red when I read this.

    So somebody said nerve signals are sent by sound and not electrical impulses? Tell that to the people who regain hearing thanks to cochlear implants (http://en.wikipedia.org/wiki/Cochlear_implant), or to the people who have prosthetics that move based on electrical impulses (http://news.bbc.co.uk/1/hi/health/1035304.stm). In fact, why not tell this to everyone who could be wasting their time doing research in the field of neuroprosthetics (http://en.wikipedia.org/wiki/Neuroprosthetics)?

    1. Re:I doubt that! by AxelBoldt · · Score: 1

      So somebody said nerve signals are sent by sound and not electrical impulses? Tell that to the people who regain hearing thanks to cochlear implants
      The authors propose that the solitons carrying the signal in the nerve cell's membrane are created and detected piezo-electrically. Here's a better writeup.
  67. Alien by PatTheGreat · · Score: 1

    In space, no one can... move their leg?

    --
    Google: "All your data are belong to us."
  68. superstrings by __aalwyc6372 · · Score: 1

    interesting theory. maybe it got something to with the supposedly smallest entities of our universe.

    somehow all the old wisdom is getting some sort of evidently proof, like:
    to be on the same wavelength with each other or that you can "smell" someone (like him). in the end we will learn, that it's all connected. after all, everything is just energy right? so it's just a matter of transformation or on a superstring level a matter of representation.

  69. read the damn thing first before propagating crap by Anonymous Coward · · Score: 0

    the summary is incorrect and TFA is total rubbish. Go read the original paper. Here is the abstract:
    Abstract
    It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton rule which is based on free energy changes in the system and thus automatically incorporates the effects of melting point depression. This model accounts for the pressure reversal of anesthesia in a quantitative manner. Further, it explains why inflammation and the addition of divalent cations reduce the effectiveness of anesthesia.

    http://www.biophysj.org/cgi/rapidpdf/biophysj.106. 099754v1?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=& author1=Heimburg&searchid=1&FIRSTINDEX=0&resourcet ype=HWCIT/

    The article is not about sound waves but about the mechanism of action of anesthetics and the proposal is that the action is not via drug binding to specific receptors but due to their affect on the thermodynamic properties of the membrane. In fact, since anesthetics screw up transmission (be that electrical or whatever) by altering membrane properties nothing can be concluded about the nature of the mechanism that they disrupt. It would be an identical situation to say that since salt can melt ice then hockey players glide over the ice not because of force applied but to the amount of pickles they eat (or smth like that).

    Slashdot becoming f.....g drudge report.

  70. PLEASE BE TRUE by IamWhoIam · · Score: 1

    Man Oh Man do I find this so exciting, and such a life saver too. I am slowly going deaf;(not so slowly if you ask my wife) it is to the point now that I have had to learn how to read lips. Unfortunately I cannot afford the cost of a hearing aide, as they are selling for 6k or more. So if this is true I should be able to hear through my fingers or any other body part I care to, or am allowed to press up against whoever is speaking. Sure wouldn't mind testing said theory with Jennifer Love Hewitt .

    --
    IF you can't be famous be infamous. But for GODS sake be something
  71. On to the net nerve by DynaSoar · · Score: 2, Informative

    If sound propagated down a nerve by sound, it'd end there. There's no mechanism to produce sound when a neurotransmitter from the first nerve mated with a receptor on the next.

    Also, we listen to brain waves with an EEG or MEG, which measure minute electrical or magnetic impulses. We do not use a microphone and amplifier. Plus, we induce currents with electricity and magnetism, not loudspeakers, and produce predictable results.

    Sound waves of sufficient intensity to propagate the full length of a nerve would be so strong in the main trunk that they'd disrupt the transport mechanism carrying neurotransmitters down from the cell body. They'd isloate the nerve from participating in the local neural network.

    A new theory should explain everything just as well as the old plus more. This one falls apart at the basics and can't handle some of the nuances.

    If sound propagation were the key, all that sodium and potassium gating to change the local membrane charge would be useless, and nature hates that kind of waste.

    --
    "I may be synthetic, but I'm not stupid." -- Bishop 341-B
    1. Re:On to the net nerve by AxelBoldt · · Score: 2, Insightful

      we listen to brain waves with an EEG or MEG, which measure minute electrical or magnetic impulses.
      As a soliton travels down a membrane, the density and thickness change. Since the membrane is full of charged and polar molecules, changing its density and thickness will generate an electric signal that can be detected.

      If sound propagation were the key, all that sodium and potassium gating to change the local membrane charge would be useless,
      No, because the sound wave is assumed to be created piezo-electrically. But it's true, in a sound model the cell has to do a lot less ion pumping; it's much more energy efficient.

      Did you know that it has been observed that the thickness of the axon's membrane changes as the nerve impulse moves through? This is a nice writeup.

    2. Re:On to the net nerve by potpie · · Score: 1

      A new theory should explain everything just as well as the old plus more.

      This is a very high standard when applied generally. Suppose somebody disproves a current theory but cannot "explain everything just as well as the old plus more." Every so often, perhaps the rudimentary must precede the complex.

      --
      Esoteric reference.
  72. Anyone else annoyed with the article summary? by buswolley · · Score: 1

    I mean C'mon: Three sentences that essentially say the same thing.

    --

    A Good Troll is better than a Bad Human.

  73. Obvious by chord.wav · · Score: 1

    a million of ravers/clubbers can't be wrong...

  74. All Old News by Video+Cat · · Score: 1

    I'd have to say all old news. To many scientists say they discovered something new, its not common that they want to change something. So I tend to stay out of arguments about stuff like this until is in a science book. Only then can anyone say its true, because then they proved otherwise it wouldn't be there.

  75. And monkeys may fly out of my butt. by God+of+Lemmings · · Score: 1

    It may sound correct however, if this were true, devices that use electrical nerve stimulation would not function properly. This is not because that sound-based neurons would not be stimulated, they likely would, but due to the fact that many designed in such a way that they block signals traveling in the opposite direction than intended. I seem to recall it was by inducing a sufficiently high level of magnetic flux in the nerve to prevent threshold voltage from being reached and causing the nerve to fire.

    Wikipedia has a very good article on action potentials and the current science we know about nerve function. It is fairly complete. http://en.wikipedia.org/wiki/Action_Potential.

    --
    Non sequitur: Your facts are uncoordinated.
    1. Re:And monkeys may fly out of my butt. by pclminion · · Score: 1

      Yes, but the transfer of a neurotransmitter from axon to dendrite could be thought of as sound, right? Obviously the whole process can't be described as just "sound" but claiming that it is purely electrical isn't right either. If you stop the physical movement of neurotransmitters the neurons are rendered useless.

  76. A very interesting analysis of slashdot posters. by Anonymous Coward · · Score: 0

    We have about 4 neuroscientists, 5- physicists, and about8 other people who seem to be able to read a journal articles.

    The rest of the herd all seem to have no ability to read the article or the commentaries before making statements that are truly asshat in nature. (not to be confused by the asshat commentaries that occasional appear in nature, which became a sub-thread in this discussion and was perhaps a more interesting and worthwhile topic).

    So,

    I didn't like anova or variogram this ((IAAE[sorta...so IASAE may be more appropriate]) but actually (IAAB) so the variogram is debateable for me to use ass I prescribe to degrees of freedom... which could be a critique of nature in itself (once again the paper as we know that nature in itself laughs at variograms and those who use them and those who critique them (although Tukey laughs in his gave at both modelers and the nature that laughs at them)), but the distribution is definitely not normal, there is a definite skewing of a 5% that has a scientific edumakayshun, and the 95% that are system administrators or something like that that read about science, and then make some online commentary because they think they are scientists as they work with computers and scientists come to ask them questions. Anyway,this surge of anti-intellectualism that seems to travel from janitors to middle managers to the current asshat president... is very depressing. It demonstrates an inability to listen to those who have a specializations in an area, and hence disregards the human species primary tool for adaptation, the ability for abstract thought to not be focused on a single topic.

    Anyway, as always... I start to comment on something in slashdot andd it makes me realize how stupid humans are and I get all apocalyptic because of the failings of the forebrain.

    I digress... I thought the paper was kinda cool and I thank the NS that dug it out... I skimmed it ffor like 3 minutes and I don't see how this is really mega earthshattering or newsworthy... what I got was that they used the gibbs equation to look at the physics of I guess you could say neuronal flux... I mean...we know that it is a fluid dynamic system so it is not going to be a semi or super conductor... but IANAP... so I have always skimmed such things...

    Anyway, I dug it, as GFE always allows us to related things that seem un-relatable to the semi-lucid mind... so "GIBBS UBER ALLES!!!" I guess is my response to the article... but

    anyway, I digressed too much, must go lift weights now.

  77. So if a tree falls... by JimDaGeek · · Score: 1

    in a forest, and I _do_ hear it, will that cause my nerve cells to react and make me like pee my pants or something? :-)

    --
    General, you are listening to a machine! Do the world a favor and don't act like one.
  78. Brown Note by ruiner13 · · Score: 1

    Then how else do YOU explain the brown note? A sound that makes you go poopie in your pants!

    --

    today is spelling optional day.

  79. Re:An article by one of the members of the res. gr by Anonymous Coward · · Score: 0

    IANANS (guess...) but I do find it very agreeable that it is odd that strength of an aneastaesia (yeah, it's misspelled) is proportional to its solubility in lipids if the inner workings of nerves are driven by electricity.


    It is not at all odd. The control of the ionic gradients of nerve impulses is known to be in the lipid bilayer of the nerve cell membranes, thus it is perfectly logical that lipid solubility of anesthetics is related to the strength of their effect.

    Sheesh, biologists and physicists can be so frustrating sometimes. I think they're both scared of chemistry.
  80. How do cells work? by HomelessInLaJolla · · Score: 1

    One needs to look at two different s of how cells communicate with each other: electrochemically and physically.

    If an impulse in a nerve cell causes a change in ionic concentration, which causes a conformational change in a surface protein, which causes a conformational change in the surface protein of an adjacent cell, then the signal was transmitted (arguably) through a physical phenomenon: sound.

    If an impulse in a nerve cell causes a change in ionic concentration, which causes a conformational change in a surface protein, which causes that protein to release a charged ion across a synapse, which ion is then gathered at a protein on an adjacent cell where the charge is passed on, then the signal was transmitted (arguably) through an energetic phenomenon: electrical.

    At the level of molecular orbitals, though, it's all about the same. A molecule or ion of a higher energy state influenced a species of a lower energy state. Energy was passed from one to the other. Since cells don't have ears I doubt that they make any distinction of how the energy is transferred.

    Think of rubbing your hands together while looking at them with infrared glasses. While you wouldn't think you're generating any light it will be clear, from the infrared glasses, that your hands, due to the increase in heat, are generating additional radiation in the form of photons in the IR range of the spectrum.

    --
    the NPG electrode was replaced with carbon blac
  81. Watson and Crick by HomelessInLaJolla · · Score: 1

    Now is a good time to point out that their of DNA was based upon work which their in lab research assistant, Rosalind Franklin, conducted. While Watson and Crick won the Nobel Prize nobody ever remembers Franklin.

    --
    the NPG electrode was replaced with carbon blac
  82. neither sonic nor electric: TFA oversimplifies by mysticgoat · · Score: 3, Insightful

    Just looking at the transmission speeds makes it clear what is going here:

    Data:

    • electricity: thousands of km/sec in any medium
    • sound: several km/sec in dense media like intracellular fluid
    • neural transmissions: meassured at a few m/sec

    Summary: neural transmission is orders of magnitude too slow to qualify as either an electrical or sonic phenomenon.

    Conclusion: TFA suggests replacing one gross oversimplification of neural transmission with another. Neural transmission might have some qualities of both but is clearly neither. TFA is garbage.

    Note Bene:There is no way of knowing what the original work was talking about. I cannot imagine anyone who has studied neural transmissions saying anything like TFA's contents. I suspect that the author of TFA was presented with an anology and took it for fact.

    1. Re:neither sonic nor electric: TFA oversimplifies by dheera · · Score: 1

      actually, that's not necessarily true. electromagnetic waves can be slowed down a lot, and the theory of electric impulses in nerves does not refer to plane waves, but movement of action potentials. it's a very different thing and their speed is heavily limited by the effective capacitances and inductances of the nerve, and the nerve's ability to keep the signal amplified. also, sound doesn't travel at several km/sec - it's more in the region of hundreds of m/sec

    2. Re:neither sonic nor electric: TFA oversimplifies by WiFiBro · · Score: 1

      Can anyone find related comments on Schwann cells (jumping), the function of myeline in the brain when not as an insulator, and how synapses are excited when not through the Na+/K+

      Further, I've read this Max Planck Institute story before, has it never been responded to in the medical journals?

    3. Re:neither sonic nor electric: TFA oversimplifies by JRHelgeson · · Score: 1

      A single nerve cell is precisely that, a single cell. These single cells, called Axons, can be as long as 3 feet (1m) long (from the base of the spine to the toes). In the blue whale, a single nerve cell can be 60' long.

      I mention this only to point out that the neurotransmitters are electro-chemical reactions. Each end of the cell has either the chemical transmitters or receptors. This is why if you sever a nerve, it stops transmitting, period. You have just severed a single cell into two cells. If you join the two halves together, it isn't going to reestablish the connection; there is no v.32bis in the neurotransmitter realm (uh, we got a noisy connection here, slow down the xmit rate until we get a clean signal)...

      If nerves simply used electricity, rejoining two severed ends would reestablish the connection. It isn't that simple. If it were transmitted by sound, then you'd be dealing with echo cancellation and crosstalk between nerve endings and we'd be able to pick up nerve activity via acoustic methods as opposed to the current electrical connections. Some physicist must have gotten a pounding headache and assumed that "teh sounderwaves in my head are echoing out of controller, argh!"... Our brain wave meters don't use microphones, dipshit, we call them electrodes for a reason.

      The whole focus of research in the genetics field on regenerating damaged nerves is to put stem cells in the damaged area and hope for 1 of 2 positive outcomes; either the severed nerve endings grow a new synapse (akin to soldering new socket/plug to each end of the severed nerve), or simply regrow and heal the severed nerve to permit the passage of the electro-chemical messenger.

      We know about neurotransmitters and their precursor chemicals, we have prescription drugs that stimulate or retard neural function (anti-depressants, Parkinson's drugs, anti-psychosis drugs). This is a well established area of neuro-science and it has been proven.

      The mere speculation of sound being the transmitter because they cannot detect heat is akin to stating the earth is flat because I can't see the curve. Thats a pretty big jump there even for Mr. Evil Knievel...

      --
      Good security is based upon reality and common sense. Common sense is a function of having common knowledge.
    4. Re:neither sonic nor electric: TFA oversimplifies by mysticgoat · · Score: 1

      also, sound doesn't travel at several km/sec - it's more in the region of hundreds of m/sec

      Good catch. In sea water, the speed of sound is 1.5 km/sec (Wikipedia. The speed in intracellular fluid would be roughly the same. This is still a couple of orders of magnitude higher than the observed speed of neural transmissions.

      the theory of electric impulses in nerves does not refer to plane waves, but movement of action potentials

      The action potential doesn't move: it is established over the entire cell membrane during the refractory or resting period by the sodium pumps. By pumping Na+ out of the cell, the cell membrane becomes a kind of capacitor, and the action potential refers to the measurable voltage between the outer and inner sides of the membrane. Talking about the "effective capacitances and inductances of the nerve" doesn't make much sense in terms of its normal functioning (though it might make sense when discussing tazer incidents, lightning strikes, and so on where there is probably movement of free electrons through the nerve cells— and other cells).

      Nerve cell transmission involves the orderly collapse of an action potential across the cell membrane, that expands from its origin like a ripple in a still pond when a pebble is tossed in. There are no "electric impulses" involved; in fact there are no free electrons involved. The process is sometimes described as an "electrochemical" phenomenon, but that too is a simplification. Calling it a "wave of depolarization" is correct in a Microsoft Help sort of way: it is a technically highly accurate description that conveys no useful information.

      The wave front is a region where there is very rapid movement of Na+ across the membrane; so in this sense the phenomenon is more one of physical movement than anything else, though at such a small scale that possibly quantum mechanical effects might be involved. In any case, the speed with which this wave propogates over the cell membrane is at a few meters per second (AIR, highest measured speeds of 2 decades ago were around 9 m/s, but more recent work might have found faster neurons, and anyway I'm trusting my wetware memory banks which aren't totally reliable for this kind of detail). This propogation of a wave of depolarization is the neural impulse through the cell.

      When I was learning about this stuff (in an earlier life, 20 - 30 years ago), it wasn't known how these impulses caused the release of neurotransmitters at the synaptic gaps, nor how the neurotransmitter substances caused the postsynaptic cell to begin collapsing its action potential. Apparently a lot of these details are still unknown.

  83. I Sing The Body... er... Sonic? by Freshly+Exhumed · · Score: 1

    Doesn't have the same pizzazz as electric...

    --
    I deny that I have not avoided attaining the opposite of that which I do not want.
  84. Makes perfect sense by Luke+Dawson · · Score: 1

    So that's why it hurts so much to watch American Idol.

  85. Silly speculation... by JRHelgeson · · Score: 1

    Next thing you know, these physicists will be fighting over whether light is a particle or a wave.

    --
    Good security is based upon reality and common sense. Common sense is a function of having common knowledge.
  86. Re:A very interesting analysis of slashdot posters by WiFiBro · · Score: 1

    Would you be offended if I suggest you to follow a Communications 101 course ?

  87. Hmmmm.... by Anonymous Coward · · Score: 0

    Is it legal to smoke pot in Copenhagen?

  88. No, not joking. by chaboud · · Score: 1

    Science is the scientific method, but the practice of science is absolutely guided by intuition and obviousness.

    You can't test it all (at least, I don't have time to), and the "hypothesize" part you're talking about is formed from our intuition and the obviousness of some theories based on available information and evidence.

    (Side note: You'd actually have a pretty hard time making my muscles "work" by pushing on my brain. Not working is a lot easier (and fun!).)

    (Side note 2: Our brains aren't "meant to operate" in any particular way, unless we were designed. Our brains do operate, and it's that operation that we use science to describe.)

    You're falling into the mistake of taking a single simple behavior and saying that, because two things could cause it, those two things are equally likely to be the root-cause/underlying-mechanism of the greater field of behaviors of the system in question. It's not one test that makes this theory highly unlikely. It's the entire field of evidence.

    It's a testament to the wikiality of Slashdot that someone using that broken style of argument could skate by as "5, Insightful" while someone calling them on it gets called a troll, only to have someone else use the same style of argument and hang onto a karmic 2.

    I'll take my licks in moderation, but you're both still horrendously wrong.

  89. I'll get you for this! by Anonymous Coward · · Score: 0

    Well if you coat yourself with a conductive material, you would become in theory a sphere...
    I did what you said, and I didn't even get slightly round, much less spherical, and now I'm all covered with this conductive polymer glop that doesn't wash off!

    You bastard...
    1. Re:I'll get you for this! by Tatarize · · Score: 1

      You don't need to be round. It should work anyway. Now go and get yourself tasered.

      --

      It is no longer uncommon to be uncommon.
  90. Barking up the wrong tree? by tgibbs · · Score: 1

    While they do cite the huge amount of research demonstrating the role of ion channels and electrical currents, they then proceed to ignore it. With respect to anesthetics, they go back to what used to be a favored theory of general anesthetic action, that they work by perturbing the structure of the membrane, which was based on the Meyer-Overton rule that potency of general anesthetics is correlated with their lipid solubility. This MO rule lost much of its persuasive power when it was discovered that effects of general anesthetics on luciferase--a soluble enzyme in the absence of membranes--also follow the MO rule. The explanation is that the interior of most proteins is also a hydrophobic "lipid like" environment even though it contains no actual lipid.

    The authors are a bit more sophisticated, citing other "lipid-like" phenomenae such as pressure reversal of general anesthesia. They are correct that this is not explained by the current model, but are probably barking up the wrong tree in retreating to the lipid model of general anesthesia. In fact, membrane proteins show a variety of interesting and poorly understood effects of pressure, so the explanation probably does not reside in a lipid-only model, but rather in a better understanding of how pressure and temperature affect membrane ion channels. It is possible that some sort of hybrid approach, taking into account interactions between proteins and membrane lipids will be necessary to achieve a full understanding. So while I think that they are on the wrong track, they are making a contribution in pointing out that there is a need for a more thermodynamic understanding of nerve conduction. I suspect that this is what led the Biophysical Journal to accept the paper, even though the authors' favored model lacks physiologically plausibility.

  91. i believe it is sound by Thomas+the+Doubter · · Score: 1

    That would explain why my ears ring. It might even explain why we all like music so much, but not electricity.

  92. L'Hermittes Syndrome by porcupine8 · · Score: 1

    I haven't done any actual research on electricity in nerves, but I have suffered from L'Hermittes Syndrome. After radiation therapy degrades the myelin sheath of your spinal cord, for several months you can shock yourself by turning your neck the right way (usually putting your chin down to your chest). It doesn't hurt, but it does feel VERY similar to the buzz you get when you touch something plugged into a wall outlet. Similar enough that I would be outright shocked if it turned out to be caused my anything other than electricity.

    --
    Warning: Apple/Nintendo fangirl. Likes her electronics cute & cuddly. May be rabid.
  93. highly suspect by headonfire · · Score: 1

    a quaintly victorian sounding theory, it is, if you ask me.

    I personally hypothesize that the aqueous flow of the nerve-system be engaged by the power of steam, the liver being the primary motivator in the cog-mechanism that enables motive energy in the body; and the primary aerators being foremost upon one's topside in the cranio-facial region, while the extricator of gaseous substances, much like an inverse smoke-stack, being found in the lower dorsal region in the form of a blow-hole.

    but maybe that's just me.

    1. Re:highly suspect by electronspiraltoroid · · Score: 1

      ROFL!!! Actually I studied this at Hertfordshire Uni back in 98, and I can assure you that the article is complete, unadulterated pseudoscience. I don't know how they got this past peer review but it gibberish. As any biology student knows, nerve transmission works by transmission of action potentials- in effect a "wave" of potassium ions moving along the nerve fibre. This wave generates an electrical potential of several tens of millivolts which can be detected using a sensitive amplifier. Interestingly, many of the problems associated with detecting the (very small) electrical signals produced by nerve fibres might be solved by the use of an electrochemical sensitive chip which measures tiny changes in potassium levels. -A

      --
      "Bother" said Pooh, as he was dipped in bees...
    2. Re:highly suspect by Legion303 · · Score: 1

      "I can assure you that the article is complete, unadulterated pseudoscience. I don't know how they got this past peer review but it gibberish."

      I wasn't aware CBC articles had to go through peer review before publication. That seems a little tedious for news purposes.

    3. Re:highly suspect by headonfire · · Score: 1

      yeah, it seems like a load of crap and goes contrary to my own medical and scientific training; but it's such a nice theory, and i'm slightly loathe to think ill of it just because it's completely f-king screwball nuts. :)

  94. I'm a nutter, but.... by Anonymous Coward · · Score: 0

    So I developed this anxiety disorder (ptsd) that cost me my $300k+ per year job. Up until that time a nuclear bomb could have gone off behind me while I was FOCUSED on a particular problem and I wouldn't have noticed. Now I have severe anxious reactions to loud sounds to the extent that I can't see through the noise at all. I'm not unemployed for fun.

    Probably no correlation.

    My 2c is let the NS's work on it no matter how far fetched.

  95. Rethinking Mary Shelly by sacrilicious · · Score: 1

    So now they'll need to rewrite Frankenstein. Instead of coming to life on a slab during a huge lightning storm, he'll need to be placed in front of the speakers at a Van Halen concert.

    --
    - First they ignore you, then they laugh at you, then ???, then profit.
  96. Rocking out by yusing · · Score: 1

    *Now* I can finally understand all those bodies gyrating on the dance floor and at rock concerts ... they're puppets on strings!

    --

    "You must try to forget all you have learned. You must begin to dream." -- Sherwood Anderson

  97. What if... by saintory · · Score: 1

    this is the missing link? That sound and electricity are related and it took a biological experiment to make this link? Going very basic here, electricity is the flow of electrons, while sound is mechanical waves propagating from a source. What if electricity is not the flow of electrons but rather the mechanical flow of energy between electrons? That what we have thought is electrons moving is actually the energy from one electron moving to another and so on and so forth? Then, in the end, electricity is nothing but mechanical energy, aka sound, moving at the speed of light.

    Disclaimer: I am not a published scientist, merely an imaginer of science fiction, also not published.

  98. I thought April 1st was next month. by Anonymous Coward · · Score: 0

    No further comment.

  99. Silly science by w1z4rd · · Score: 1
    I really hate stuff like this.

    Theoretical physicists who think they know more than any other type of scientist simply because they are .... (gasp and awe) ..... physicists! This is just another instance of people trying to generate some media buzz over nothing."

    Heimburg and Jackson theorize that sound propagation is a much more likely explanation.

    "It's not a "much more likely" explanation at all. Not even slightly.

    Propagation of membrane potentials by salutatory conduction along axons (ie. electrical nerve impulses) is confirmed countless times every day all over the world via the endless scientific experiments and medical procedures that are based on that theory. Every level of biology (from the genetic level to the biochemical level to the cellular level to the whole organism level) confirms the electrical impulse theory.

    And here's the clincher...

    "Although sound waves usually weaken as they spread out, a medium with the right physical properties could create a special kind of sound pulse or "soliton" that can propagate without spreading or losing strength. "

    Oh I see. So in order to substantiate their unproven idea that nerve impulses are actually sound and not electrical in nature, they are invoking an unknown and theoretical set of physiological conditions that must be present in order for their theory to be correct! What absurd circular logic.

  100. I dont need no stinking subject by Chicken04GTO · · Score: 2, Insightful

    Slashdot needs a way to "thumbs down" stupid articles so they disappear.

  101. An open letter by Anonymous Coward · · Score: 0

    Also, they couldn't reach the authors for comments, which probably explains the awkward spin on the research.


    Unfortunately, I went to the research paper before fully reading the CBC article. If only I had read that final sentence!

    OPEN LETTER TO THE EDITORS OF REPUTABLE (if you really, really think it is reputable) NEWS SOURCES:

    Dear Editors,

    Please refrain from publishing any article about a scientific study that includes the phrase, "Scientists say..." in the title yet also includes in the body something similar to, "The researchers could not immediately be reached for comment." It is embarrassing for a scientist to have his/her work spun in an uninformed or misleading way, especially when you do not give them a chance to correct you! It is also a stain on your own reputation to publish such material and a disservice to those of us who do not read primary research literature regularly, but rather rely on general news sources for science news.

    Love & Kisses,
    Your Readers