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until you factor in the inevitable greed variable from the Pharmaceutical Cartel.

No surprise here, especially considering that this one is really a study by Cortexyme, Inc that is developing treatments for Alzheimer's and other degenerative disorders.

The list of authors and affiliations should be enough to give anyone pause: of the 13 authors the corresponding one (i.e., the one who got the study published) is Stephen S. Dominy from Cortexyme, Hatice Hasturk is affiliated with The Forsyth Institute "reinventing oral and overall health through pioneering biomedical research and transformational healthcare practices", and most of the others come from departments of oral immunology, dental medicine, periodontology, etc.

This alone should be enough to make anyone very suspicious but, in the event it isn't, the introduction clearly states:

"Infectious agents have been found in the brain and postulated to be involved with AD, but robust evidence of causation has not been established
[...]
P. gingivalis lipopolysaccharide has been detected in human AD brains, promoting the hypothesis that P. gingivalis infection of the brain plays a role in AD pathogenesis.
[...]
We developed and tested potent, selective, brain-penetrant, small-molecule gingipain inhibitors in vivo. Our results indicate that small-molecule inhibition of gingipains has the potential to be disease modifying in AD."

So, according to the author(s) there is "no robust evidence" that P. gingivalis is really the cause of AD, but Cortexyme will be happy to sell you something that may (or may not) work. In other words, the article is just another press release in disguise.

RT.

Mozilla Corporation cut Thunderbird loose ~ 2007, and the primary developer started his own commercial version called PostBox.

In their most recent version they added support for maildir in addition to mbox (a long requested feature on bugzilla).

The source code appears to be available for older versions, but I'm unclear if they are contributing back to the master repository anymore, or just a fork.

I bought it to support development, but I rarely use a client nowadays other than email provider's web client.

I wonder if anyone else has tried it?

Unsophisticated investors like Google, JP Morgan, and Alibaba?

check out the full list.

Your skill in anal diction is truly astounding.

Laurie Voss, co-founder and COO of npm - citing herself? /cynical

A quick Google search reveals that Laurie Voss is male:

https://www.crunchbase.com/person/laurie-voss

I don't know anything about him, since I don't pay much attention to Javascript in general, but I just want to prevent a huge whine-fest here on Slashdot, with dozens of victimized MRAs sobbing about how unjust it all is, before it happens.

Huh. I would have guessed it was entirely VCs, but apparently they've been getting funding lately from banks, including Morgan Stanley and Softbank. My guess is they were able to get better terms from the banks? An alternate explanation is that they were planning on going public soon, I guess.

Uber's had $11billion worth of funding so far, and they're leaking money like a leaky lawyer, but they should be able to survive with that money lost (of course they are absolutely losing this lawsuit).

Still, waste a billion here and a billion there, pretty soon it adds up to real money. Waymo than I have.

https://www.crunchbase.com/org...

Burning through $150 million in funding since 2013 ($88000 per DAY including weekends), they might as well have been juicing actual money.

If this site can be trusted, the global smartphone market is some 400 billion dollars annually. The total invested in Essential to date seems to be around 300 million, which is definitely real money, but not necessarily a shocking figure. Something like 30-50 billion of VC funding gets thrown around on a quarterly basis. Andy Rubin has as good a chance as anyone to be able to deliver some value for that money, and he can probably be counted on to be able to put together a good team as well. If Uber can lose billions annually without anyone batting an eye then I don't know why these guys deserve the press, or why the "...without shipping a product" angle was necessary. Are we expecting that they're somehow less likely to do with the additional funding? Is there some part of bringing a smartphone to market that's expected to be quick, cheap, and easy?

Apparently it's a slow news day.

It had raised more than $580 million in funding from top investors like Khosla Ventures, Mayfield Fund, Andreessen Horowitz, Sequoia Capital, and Kleiner Perkins.... and... BlackRock, which loaned Jawbone $300 million in 2015, which has a stake in the new company

Plus 14 rounds of funding.

How is this CEO still trusted with anybody's money if he blew through over half a billion dollars? #SuckerBornEveryMinute

Who's the cat that won't cop out when there's danger all about? (Schaft)
Right on

You need to be kinda old to get this one.

Yeah, well, welcome to Slashdot.

Hmmph. If this were properly Slashdot, it would have been the correct old reference. Schaft Enterprises was originally a fictional manufacturer of military Labors in Europe and the US in the Patlabor anime series from 1989-1990. The company designed and manufactured the Griffin Labor, a recurring (and starring) antagonist. The real Japanese company Schaft was founded in 2012, with the name obviously chosen as an homage to the series/movies/manga.

You'd have thought they'd have chosen Shinohara Heavy Industries instead (the Japanese company in the series that manufactures the starring Ingram Labor), but they were indulging in a quintessentially Japanese bit of irony. Schaft was founded to allow its principals to accept money from military sources, specifically the US DARPA, who had issued their Grand Challenge in robotics, with prize money. As researchers at the University of Tokyo, they would not have been allowed to accept any money from DARPA. So naturally when choosing a name, they went with the rebellious criminal company name, rather than the establishment respectable name.

And get off my lawn!

He needs the money

Amazon raised $8 million before going IPO. Financial reports for pre-and-post IPO raises are radically different - you have to prove future value (profit) or you won't get any stock price increase. Uber, on the other hand, has raised close to $3 billion, has no path to profitability, and is burning cash at an astronomical rate. Amazon was a small bet - Uber is putting everything your entire family owns on 11 black and watching the marble roll...

Amazon raised $8 million before going IPO. Financial reports for pre-and-post IPO raises are radically different - you have to prove future value (profit) or you won't get any stock price increase. Uber, on the other hand, has raised close to $3 billion, has no path to profitability, and is burning cash at an astronomical rate. Amazon was a small bet - Uber is putting everything your entire family owns on 11 black and watching the marble roll...

Slack and GitHub Both are backed by Jared Kushner's VC firm and both should be considered tools of the Republican Trump Administration at this point.

Thrive Capital is a major backer of both:

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

Slack and GitHub Both are backed by Jared Kushner's VC firm and both should be considered tools of the Republican Trump Administration at this point.

Thrive Capital is a major backer of both:

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

Slack and GitHub Both are backed by Jared Kushner's VC firm and both should be considered tools of the Republican Trump Administration at this point.

Thrive Capital is a major backer of both:

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

https://www.crunchbase.com/org...

All of Musk's businesses lose money every year. Where exactly do they get the funds for all this expansion, or for the Gigafactory or the Tesla 3 tooling and production?

Maybe your news sources are not reliable. Musk's previous business efforts have made a ton of profit and he has reinvested his own funds in his more recent efforts. Tesla is a public stock company, so both institutions and individuals are invested in it. SpaceX is privately funded, you can see who the investors are here.

https://www.crunchbase.com/org...
Total Equity Funding
$1.13M in 2 Rounds from 2 Investors
Most Recent Funding
$130k Seed on August 1, 2016
Headquarters:
Santa Clara, California
Description:
Taking the search out of job search with a patent pending customized platform utilizing NLP and Machine Learning.
Founders:
Isaac Choi
Categories:
Employment, SaaS, Machine Learning, Natural Language Processing, Text Analytics
Website:
http://wrkriot.om/

Company Details
Founded:
November 1, 2015
Aliases:
JobSonic
Employees:
11 - 50 | 1 in CrunchBase
JobSonic is currently trying to make sure that job search engines cater to the needs of the job seekers by allowing them to be matched and ranked to all job postings in real-time. We have created a data driven job board using the latest technologies in natural language processing, text analytics and machine learning. Our goal is to make sure that all the people in the world will have an opportunity to work in a full time job positions and are able to get all the benefits needed to live without any worries concerning their health and retirement.
Everyone deserves the right to work, provide, save and grow for their family. Everybody should be allowed the right to better themselves and in this current economic downfall people are being pushed into working for the on-demand market, which is actually suppressing people.
We do this by allowing a person's resumes to be matched through signal classifications to every job posting on the web within their desired industries, salaries and locations in real time. Not only are their resumes matched, but the job postings will be ranked in order from the highest possible choices to the lowest.

have you tried the commercial version?

https://www.postbox-inc.com/pr...

Mozilla separated itself from the main Thunderbird developer in 2007 and he released Postbox 1.0 in September 2009.

http://scott-macgregor.org/blo...

https://www.crunchbase.com/per...

Jobs available backed by 121 million in VC funding- https://21.co/#jobs

Companies investing 121 million in 21INC - https://www.crunchbase.com/org...

More details - http://www.coindesk.com/21-int...

better article - https://medium.com/@21dotco/a-...

Reason Why Qualcomm may be so interested - https://www.youtube.com/watch?...

> Start with a bicycle or go-kart and work your way up.

That's actually how JB Straubel, Tesla's CTO, started when he was a teenager:

https://www.crunchbase.com/per...

This site that "no one has has ever heard of" managed to squeeze out $22M in VC money. It was a navel-gazing site for silicon valley that made it's money through subscriptions to exclusive content and ads.

The list concentrated on money. EG sponsorship. This ignores contributions and resources directly contributing code.

http://intel-iscsi.sourceforge...
http://www.crunchbase.com/orga...
https://www.virtualbox.org/wik...
http://www.libreoffice.org/

Thomas Massie is a tech guy with a bachelor's degree in Electrical Engineering & a master's in Mechanical Engineering from MIT, and founded SensAble. I'm sure he had to do quite a bit of coding in his time in school, and probably a bit while he was building his company as well.

http://www.crunchbase.com/orga...

about that failed phone company

"Status
        Acquired by Google on May 20, 2011"

seems somebody wanted it.

How did I miss this halcyon era when Internet ads were "fun and informative"?

The rentals section of Craigslist and their jobs offered section are actually useful and informative for the users (although admittedly, I don't think those sections are considered "fun" unless you include the free sections of Craigslist) . Those two sections, rentals and jobs, require money to post each listing. If those paid sections didn't have such a barrier to entry, then they would be swamped with spam and duplicate posts, even more spam and duplicate posts than other sections on Craigslist already have.

But aside from Craigslist, I'm not aware of any company that has made paid advertisements useful for the actual users. And since Snapchat has already accepted 50 million of dollars for its C Series funding from a well known hedge fund, Snapchat will be required to become the next Facebook, or die trying, and in my personal opinion that never bodes well for the users.

Along that line of thought, Facebook recently bought Osmeta. Hard to say why, but they might be related.

Although, Her Twitter seems a more promising contact channel. Still active.

After reading through other linked profles from her Google Plus profile, especially the CrunchBase one, I'm getting pretty confident that I've nailed it.

Who else would have the power to force through such a profound destruction of value, stretched through such a long time period without any checks?

If you really want this madness stopped, petition the boss of Dice Holdings, Michael P. Durney - President and CEO or possibly Klavs Miller - Senior Vice President, Technology.

If someone else better skilled in writing would make a petition on http://www.petitiononline.com/ and direct it at those guys, that would be so much more effective than ranting here in comments, which these people probably had never looked at.

Although, Her Twitter seems a more promising contact channel. Still active.

After reading through other linked profles from her Google Plus profile, especially the CrunchBase one, I'm getting pretty confident that I've nailed it:

Hill was named Managing Director of Dice.com in November 2010. She is responsible for the development and direction of all activities for Dice.com, with particular emphasis on product development and innovation, building and maintaining industry presence, and managing large account sales. Dice.com, a Dice Holdings company, is the leading career website for technology and engineering professionals, and the companies that seek to employ them. NYSE: DHX

in 2012 Hill was appointed President of Slashdot Media - running the SF and NY-based company and its three media properties, SourceForge, Slashdot and FreeCode. Slashdot Media is owned by parent Company Dice Holdings, Inc.

Who else would have the power to force through such a profound destruction of value, stretched through such a long time period without any checks?

Neither company does the ubiquitous tracking and analysis that Google does.

I wonder what these jobs are for then?
Data Scientist - Ads - 858668 Job
Data Scientist - Marketing - Data and Analytics - 849750 Job

Yahoo was doing user & ad analytics before Google existed.

And remember everyone, only one company was on the original PRISM slide, so the NSA definitely can't get to you at Microsoft(2007) Yahoo(2008) or Apple(2012). Since it isn't listed, DuckDuckGo will be impervious to NSA attacks; with all of its employees you can be sure at least one of them works on security and can outsmart the NSA's ability to install hardware backdoors and hack air-gapped computers.

Marissa Mayer as a counter example..

A private company receives somewhere less than $90 million in funding (half which was received last month) and manages to create a new type of cheap sea-based platform and currently has over a hundred of them active.

In contrast, the typical space probe is a hideously expensive, one-off design made by people who have no interest in reducing the cost of the platform. In the past, I've advocated developing space probes in batches or iterative generations instead. This is an example of why.

There are some obvious differences. Space is much more expensive to access at $5-10k per kg just to reach low Earth orbit. While these guys can just drive up to a beach. Space also is a harsher environment. It doesn't have full time exposure to sea water, but it does have hard radiation, temperature extremes, and heat dissipation issues.

Even so, this is how you do things economically. Making multiple copies of a probe design means that you spread out R&D costs over more probes - R&D is a large cost currently of space probes. You also get "learning curve" effects where the marginal cost of manufacturing, operation, and management of probes goes down as you make and deploy more of them. You "learn" (or rather exploit various economies of scale for these processes) how to do this better.

End result is more probes and more work done for the same amount of money spent.

WTF? I'm gonna assume this was intended to be funny, but it's sitting at +3 Interesting

1) Code.org is not run by microsoft. It's a non-profit founded by Hadi Partovi

2) Code.org doesn't promote microsoft coding habits. I can't actually find any microsoft languages on their site.

3) I'm not cetain who "they" refers to in the 3rd sentence, but Code.org doesn't have anything to say about outsourcing tech jobs. If it's referring to Microsoft, then Facebook, Yahoo, Google, Cisco and Intel also signed the letter requesting an overhaul of the tech visa system

4) westerners who...think independently. Yep, that's some pretty "independent" thinking thinking you've got going there. It's so independent, it may form it's own little country with a flag and national anthem.

5) This is all helped by a whole host of corporate artists, celebrities, and other proffesional astro-turfers. Huh?

Sadly, as bat-sh-t crazy as your description was...it still made more sense than the article.

The kind of information they want to put in these codes could just be printed in clear text. This is just one company trying to get into a middle-man position where no middle-man is needed.

Exactly. Or link it to a drivers license or state ID, there's no reason to have an extra sticker that emergency medical personal are trying to search for. I can just see them running around searching for a sticker.
EMT #1: Check his wallet
EMT #2: Not there
EMT #1: Where's the helmet?
EMT #2: I don't see it on there either
EMT #1: Well screw it, we can't spend all night searching for a sticker!

WE already have state IDs, why not just use those? Even children can get a state ID. Put your ID number in a database and update that with medical information. Done. The irony here is on Lifesquare's website they have the EMT looking at the person's wallet and finding the sticker in the wallet. FAIL.

And how is this going to be profitable? Are you going to charge users for the stickers? Maybe a monthly subscription fee? Good luck with that. Or the hospitals should all pay monthly? A project like this is too big for a tiny startup, this needs to be done on a state wide government scale to be successful at all.

But it looks like Lifesquare is available in Marin County, CA. That's great, funding January 2011 and by June 2012 you have 1 county covered and only 3,140 counties to go.

Whenever I hear about these horrible startups I always wonder how much funding they've received. Unfortunately it doesn't say the amount, but it does say someone gave them venture funding for this really bad startup.

If you don't like one Ticket Processor's practices, okay. Then don't go to shows at venues that use that Ticket Processor. Capitalism might be able to fix this yet.

For what it's worth, I have gone to countless shows w/o paying a dime to Ticket Master. That doesn't mean I don't pay fees, but the ones I pay are a lot more reasonable ($10 plus fees with Ticket Master vs $3-5 fees elsewhere). And the option of going to the venue and buying tickets directly to avoid fees.

AOL still exists? Wow.

AOL has been riding the profits from its dying dialup business to relaunch itself as an internet content and advertising business. They actually have a fairly large stable of brands besides their own Autos or Shopping channels. Poking around their corporate site, here is a list of sites they operate: 5min, advertising, about.me, adtech, AIM, autoblog, cambio, citysbest, comicsalliance, dailyfinance, engadget, everydayhealth, gadling, games, giseleandthegreenteam, goodnewsnetwork, goviral, holidash,huffington post, joystiq, jsyk, kitchendaily, mapquest, mmafighting, moviefone, noisecreep, patch, pawnation, pictela, seed, shortcuts, shoutcast, slashcontrol, smckids, spinner, streampad, studionow, stylist, theboombox, theboot, techcrunch, tuaw, tuvozentuvida, winamp, wow and probably a bunch of others I couldn't find. While some of these might not be top of mind, combined they represent a huge pile of pageviews and traffic. There is also a nice set of investments in new sties tracked on crunchbase: http://www.crunchbase.com/financial-organization/aol-ventures

Really? Because, you know, multiple other sources say that Zuckerberg started the prototype in September of 2003, and what we know as Facebook was launched in February of 2004.

If I recall rightIy, my vt.edu email address allowed me to register sometime in late 2004 or early 2005. On campus, it was starting to generate a lot of buzz as a great tool to bring lots of people together on short notice.

Your response is typical of what I was talking about though -- memory is a strange and elastic thing. You've been on Facebook for so long it feels like it's been 8 years, but it hasn't, and it really couldn't possibly have been.

WTF is with Facebook and 500+ engineers?

Meetup.com has 63 people, not all engineers, and they deal with a client base which uses their product in a much more demanding way than Facebook's users. I look at Meetup.com as more of a performance-critical application, at least in terms of their users. If Meetup gets a bug, it affects whole groups of people - a lot of them engaged in technical, educational, aid and political activities - trying to organise themselves. I'd like to say it again - *63 employees*.

Facebook, on it's face (so to speak), is not rocket science. Neither is Meetup. This indicates to me that there's a LOT going on behind the scenes and most of it has to do with implementing the API and other technology to support all the marketing, advertising, strategic partnerships, etc. Either that or the UI changes are deceptively complicated.

Yeah, I'd love to know what those 500 people are mostly coding. Perhaps this is an indication of the difference between an advertising-run business vs subscription. One of them allows you to get on with what matters to your users. If anything shows where Facebooks's primary focus is, this does.

Hmmm, again, info@fabulis.com does not appear to be good enough for you. How about this then or this. Any google search for Jason Goldberg + Fabulis turns up a ton of news articles, information about the site, it's investors and his past endeavors, like xing. It all looks pretty lame to me, but I think that about Facebook and Twitter too. Other then looking like another useless social media site I don't see anything wrong with it and it doesn't feel scammy to me unless you also think twitter and facebook (and Buzz!) are scammy.

Yes, I do feel twitter and facebook are scammy, but I don't see any problems with Fabulis.

Hmmm, again, info@fabulis.com does not appear to be good enough for you. How about this then or this. Any google search for Jason Goldberg + Fabulis turns up a ton of news articles, information about the site, it's investors and his past endeavors, like xing. It all looks pretty lame to me, but I think that about Facebook and Twitter too. Other then looking like another useless social media site I don't see anything wrong with it and it doesn't feel scammy to me unless you also think twitter and facebook (and Buzz!) are scammy.

Explain real world contact info. Jason Goldberg links two news articles that contain a lot of data on who founded and invested in this company. If you take a sec to google him there is plenty of data on him here: Jason Goldberg on Crunchbase. What? Because his contact info on the site is info@fabulis.com? That's pretty standard actually. Just because he doesn't list his home phone number and personal email address doesn't make him anonymous. He doesn't seem to have anything to hide, quite the contrary actually given the nature of the site. Just because he doesn't list his personal contact info for you to contact doesn't mean Citibank doesn't have it.

My guess is that this is a good old fashion case of homophobia. Especially after reading this: Update on story.

Plurk is CANADIAN. The user base is Taiwanese, but it is originally based out of Canada. Link for proof

I think robots.txt is retroactive on a page.

Also, I am willing to bet many just show up if they are large.

Example, I am interested in organic chemistry, currently I would go to wikipedia, after this change organic-chemistry.org (based on google results).

I bet blogger.com pages show up in searches for people that would not go their too. True sites like facebook would not suffer as much, and it is those sites where the stradegy would work.

I know people that type facebook into their google homepage to get results, and go to facebook (location bars purpose escapes them). if they were to not get to facebook that way, it would make google look terrible.

http://www.crunchbase.com/company/facebook is not the result they want when typing facebook into google.

TechCrunch sucks at Pandora's teat

Pandora is often the official "DJ" at TechCrunch clusterfucks

"Then why isn't there an SSH client shown in the screenshot instead of that persistent SGV clock?"

That is the most stupid question I have been asked in a very long time.

I did a search on the guy who posted this crap - Charlie Demerjian - and found a listing of his other fine, fine work:

http://www.crunchbase.com/bloggerboard/tech/author/charlie-demerjian

It's mostly sensationalist FUD and hearsay. Seriously, how does shit like this get posted? Especially from morons like this guy?

Looks like they have un-moderated commenting allowed on their site Head on over, kids!