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Designer Babies, Version 1.0

Stickerboy writes: "A 30 year-old woman in Chicago gave birth to a pre-pregnancy genetically screened and selected baby 17 months ago, which is being reported in the Journal of the American Medical Association today. Doctors at the Reproductive Genetics Institute in Chicago took 23 eggs from her, screened the eggs for a gene that causes an early form of Alzheimer's, and then fertilized and implanted the eggs back in her womb. Shades of the movie Gattaca - this is a good specific development, but the start of a very controversial trend. Read more about it in the Washington Post or read the abstract in JAMA."

514 comments

  1. all they did was screen for alzheimers? by delphin42 · · Score: 1

    Why didn't they do anything else interesting. If you are going to screen for something, why not go all out?

    --
    -- Adam
    1. Re:all they did was screen for alzheimers? by swordboy · · Score: 3, Funny

      Yes,

      Perhaps they could screen for the 'first post' gene as well...

      Sigh...

      --

      Life is the leading cause of death in America.
    2. Re:all they did was screen for alzheimers? by ShaunC · · Score: 4, Funny

      >Why didn't they do anything else interesting.

      They were going to, but they forgot. If only the early Alzheimer's detection had been available a generation sooner...

      Shaun

      --
      Thanks to the War on Drugs, it's easier to buy meth than it is to buy cold medicine!
    3. Re:all they did was screen for alzheimers? by gorillasoft · · Score: 4, Informative

      Why didn't they do anything else interesting. If you are going to screen for something, why not go all out?

      Read the article - her family had a history of very early alzheimers, where they would be in the full stages of it by age 40. This was an attempt to prevent the 50% likelihood of the offspring having alzheimers by age 40 as well.

    4. Re:all they did was screen for alzheimers? by xcomputer_man · · Score: 0, Offtopic

      Or better still, they could have screened for
      Troll gene and delivered the rest of us /.ers
      from yet another lamer. :)

    5. Re:all they did was screen for alzheimers? by 2Bits · · Score: 2

      I don't mind what kind of genes they are screening, Alzheimer's, cancer mutation gene, or whatever. As long as they don't try to make babies with IQ of 200+ by genetic engineering.

      Look, I don't want to be the last generation of dumb humans, ok?

    6. Re:all they did was screen for alzheimers? by hij · · Score: 1

      they should have tried to stop this.

      --
      Believe nothing -- Buddha
    7. Re:all they did was screen for alzheimers? by sd211 · · Score: 1

      They had to take cells from the embryo; the analysis is destructive (probably Polymerase Chain Reaction, or PCR). One cannot take too many cells from the embyo, have to leave some for the embryo to develop. This limits number of screens. Since the woman had family history of Alzheimer's it is the obvious choice.

    8. Re:all they did was screen for alzheimers? by nurightshu · · Score: 2

      One cannot take too many cells from the embyo, have to leave some for the embryo to develop.

      Actually, IIRC, up until the number of cells reaches some pre-determined threshhold (I believe it's 2^16, but please don't hold me to that one), each of the embryonic cells is fully capable of developing an individual human being -- that's how identical twins occur. So really, at any point past the first mitosis, you can take a cell or two or even twenty, just as long as you leave one behind to develop.

      --
      They that would sacrifice their .sig space for that cliched Franklin quote deserve neither.
    9. Re:all they did was screen for alzheimers? by Anonymous Coward · · Score: 0

      I don't know about you, but with the knowledge that I may contain genes to produce a baby with a serious genetic error makes me NOT want to have a baby. Call it natural selection. At least I have the foresight to make an INFORMED decison. And then, if I need a kid or two, I can look into adopting one of the millions of lost children already here. It certainly does not make me want to sit on a microwave or something to change my DNA. Hopefully.

    10. Re:all they did was screen for alzheimers? by Anonymous Coward · · Score: 0

      in the future, you will be able to take your sperm, list out the possible people you could make from it, age them to say, 20 years old, clone them out so they grow super fast and are given limited motor abilities via brain imaging, then, they can be your own personal sex slave. maybe it's just the sick perverted part of me saying this.

    11. Re:all they did was screen for alzheimers? by Anonymous Coward · · Score: 0

      I take out my sperm on a regular basis right now, but it usually gets flushed down the toilet very shortly after. (Well, sometimes I let my "chick of the night" ingest it but I digress.)

  2. What gene combo do I need to by Unknown+Poltroon · · Score: 0, Offtopic

    get all the best parts of Cowboy Neal in my baby?

    --
    All Troll + "offtopic" mods are meta moderated as "Unfair", because you abused the system.
  3. hmm by mar1no · · Score: 1, Funny

    They should made a terminator babe with metal as bones, that'd be sweet.

    --
    "you sonofabitch i didn't know!"
  4. This is great news by Exmet+Paff+Daxx · · Score: 0, Troll

    My wife and I are actually quite young, and I'm trying to persuade her to wait until Science advances to the point that we can select the gender and fitness level of our child. I've always wanted an athletic young son, and considering the irreplacable amount of money and time it takes to raise a child, this only makes sense.

    I'm forwarding her this article now; perhaps this will convince her I'm not such a dreamer after all.

    --
    If guns kill people, then CmdrTaco's keyboard misspells words.
    1. Re:This is great news by smoondog · · Score: 2

      For you and your families sake, I really hope you are a troll.

      -Sean

    2. Re:This is great news by delcielo · · Score: 2

      I hope you're not serious. To choose one egg over the others rather than letting nature (and I might add, natural selection) run its course just because you always wanted an athletic son is ridiculous. How egocentric is that? Wow.

      I couldn't quite tell by the tone of your post if you were really serious, or just being sarcastic. I hope it was the latter.

      --
      Hot Damn! It's the Soggy Bottom Boys!
    3. Re:This is great news by jcsehak · · Score: 1

      What happens when that athletic young son turn into a slashdot reader?

      --

      c-hack.com |
    4. Re:This is great news by Anonymous Coward · · Score: 0

      He will, shortly after dealing with the dolts, either a. become a ward of the state, afflicted with terriable predisposition of stupidity and homosexuality, or b> realize he is on the path to 'a' and shoot himself.

    5. Re:This is great news by poopybum · · Score: 1

      First: You're kidding right? Second: Ever read 1984, Brave New World.... Third: Sex is FUN!!!!

    6. Re:This is great news by lilzabubba · · Score: 1

      What happens when your kid jock gets killed in a drunken car accident before age 20? They can't screen out the stupidity gene.

    7. Re:This is great news by F2F · · Score: 1

      i'd mod you up, but i gave up my moderation points a year ago :)

      like third point...

      you like my id? :)

  5. Some things are good some are bad by smoondog · · Score: 3, Insightful

    I think we can sum up the solution to this debate relatively easily:

    Babies free from disease == Good

    Babies who look like Arnold Schwartzenegger and Maria Shriver == Bad

    -Sean

    1. Re:Some things are good some are bad by Anonymous Coward · · Score: 3, Funny

      Babies who look like Arnold Schwartzenegger and Maria Shriver == Bad

      You're right, they should pick one person to look like and leave it at that.

    2. Re:Some things are good some are bad by chinton · · Score: 1, Interesting
      Babies free from disease == Good

      Even that noble goal is a slippery slope to tread. What diseases do we screen for? Cancer? Diabetes? Sickle Cell? ADD? Psoriosis? Dandruff? Halitosis?

    3. Re:Some things are good some are bad by kwashiorkor · · Score: 2

      I'm willing to bet that most people consider ugliness a disease. Look around you, there are more "cures" for ugliness than there are for anything else. I'm sure that at the first opportunity, Calvin Klein and the rest of the fashion mafia will be producing true "designer" babies.

      --
      -- kwashiorkor --
      Leaps in Logic
      should not be confused with
      Jumping to Conclusions.
    4. Re:Some things are good some are bad by Another+MacHack · · Score: 2, Insightful

      Why not screen against those things? Is it somehow morally necessary for a certain fraction of the population to have severe dandruff?

    5. Re:Some things are good some are bad by Anonymous Coward · · Score: 1, Insightful

      All of them. Please enlighten me as to how disease is good. And, since you are obviously a bit on a slow side, dandruff isn't a disease. Get a water softner and a fucking humidifier. Are you going to pull some bullshit fucked argument that disease is a good thing? I'm waiting. This ought to be good.

    6. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      Look at it this way: if all of a sudden only the beautiful babies are selected (assuming beauty is all-important to you), eventually, all the beautiful people won't be attracted to each other, they'll be attracted to people have normal diversity in appearance... which means us norms will have supermodels up to our ears...

      or something like that...

    7. Re:Some things are good some are bad by broter · · Score: 2, Informative
      • Why not screen against those things?...

      The problem I can see right now is that we don't know how the presence or absence of a gene can effect other things in a given pathway. For example, the gene in mice that's responsible for aging also resonsible for cancer resistance. This is a well known problem that is only now being able to be explored in prokaryotes.

      --
      "One man can change the world with a bullet in the right place."
      - Mick Travis, "If..."
    8. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      I'm willing to bet that most people consider ugliness a disease. Look around you, there are more "cures" for ugliness than there are for anything else. I'm sure that at the first opportunity, Calvin Klein and the rest of the fashion mafia will be producing true "designer" babies.

      The problem is, when everyone starts looking the same they will no longer be considered beautiful - it will be the "odd-looking" ones who are now different enough to be desireable.

    9. Re:Some things are good some are bad by Mr.+Slippery · · Score: 3, Insightful
      Babies free from disease == Good Even that noble goal is a slippery slope to tread. What diseases do we screen for?

      And what do we consider a disease?

      Recall that not that long ago in the U.S., homosexuality was offically considered a "disease".

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    10. Re:Some things are good some are bad by Aqualung · · Score: 1

      Is it somehow morally necessary for a certain fraction of the population to have severe dandruff?

      Morally necessary? Probably not... but what do we do with all those former Head & Shoulders employees in our new, dandruff-free society?

      --

      - Dave
    11. Re:Some things are good some are bad by Irvu · · Score: 2, Insightful

      True fact. The gene that is linked to Sickle-Cell Anemia only causes it under unlikely mutations. If you are a carrier of this gene however, it provides a degree of protection against Malaria. Therefore it is found most often in malarial reigions of the world.

      The issue is, If we wipe out a disease such as sickle cell from the worlds population then those people who live in malarial reigons will be far more at risk possibly causing large-scale epidemics.

      Healthy babies are good but not if preventing one disease causes an outbreak of another possibly worse one. We have to be careful about our assumption that we *know* what will happen. This is what all the nonfiction opponents of genetic engineering are really on about. We simply *dont* know what all of our genes do or how they behave in specific combinations and under specific conditions. There are just so many possibilities that total prediction and total control is not possible.

      Gattaca was less about genetic engineering as ego and fear. It showed a socity so wrapped in its own genetic confidence and so afraid of its own diseases that babies with a 10% chance of heart disease were treated as if they were already dead. The assumption that say the likely appearence of a gene coding for melanin in the skin meant that you were permanantly incapable of any significant task no matter how smart you actually were.

    12. Re:Some things are good some are bad by LordNimon · · Score: 3, Interesting
      Is it somehow morally necessary for a certain fraction of the population to have severe dandruff?

      Unfortunately, yes. Many of the world's greatest artists, writers, and musicians had genetic "defects" of some kind. For these people, their problems are what drove them to greatness.

      --
      And the men who hold high places must be the ones who start
      To mold a new reality... closer to the heart
    13. Re:Some things are good some are bad by stienman · · Score: 4, Insightful

      The ability to screen for these is directly related to the financial status of the person using the screening system. The poor would go the 'natural' way and subsequently become a lower class physically than families who can afford such procedures. As can be seen in every society documented or studied, physical differences lead to class tendencies. Even if it were illegal to discriminate based on some physical triat, it would happen and become the norm in many industries, pushing the lower class even lower.

      Plus it require a LOT of government control and intervention to prevent such discrimination, reducing individual privacy and rights.

      But we won't be around long enough to see it, so how about if we jump in with both feet and darn the consequences... We'll create a better class of geeks! Or at least ones with 6 fingers (better keyboarding) or a mousing hand or something.

      -Adam

    14. Re:Some things are good some are bad by 4of12 · · Score: 2

      most people consider ugliness a disease

      Exactly.

      I was going to suggest the same thing. You could probably add to the list of diseases the tragic syndromes of being too short, athletically less than Olympian, or having a metabolism that modern diets wreck with type II diabetes.

      Other "diseases" include lack of intelligence, lack of creativity, and lack of obeying authority.

      It'll be interesting to see how this facet of eugenics plays out. I'm not sure that most parents really want Baby to inherit DNA from other sources than themselves - there's a matter of ego and pride involved.

      Already, you can see in various cultures like China the effects of screening for "femaleness", another "tragic disease". There are some profound repercussions that have already been set in motion from that kind of mentality. I would not be surprised to see females more valued in the future as they become scarcer.

      --
      "Provided by the management for your protection."
    15. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      LOL..damn, this is good stuff.

    16. Re:Some things are good some are bad by Reality+Master+101 · · Score: 3, Insightful

      Recall that not that long ago in the U.S., homosexuality was offically considered a "disease".

      Well, calling something a "disease" is a loaded statement. I'm pretty convinced that there are two types of homosexuality: genetic based (where your sexual attraction mechanism is backwards), and psychologically based.

      For genetic based homosexulity, there is no question that it is a genetic defect to be attracted to the wrong sex (I mean, duh). I would not do post-fertilized screening, but if it were possible to screen my sperm or my wife's egg for the defect, I would certainly do it.

      On the other hand, psychologically-based homosexuality is debatable whether it's a "problem" or not. The truth is that it probably is in some cases, and not in others. For example, a severely abused woman who chooses lesbianism because of the abuse is probably a candidate for counseling. On the other hand, if you simply had a person whose personality encouraged "trying different things", and simply preferred homosexuality, then it's probably not a problem.

      Once again it has to be pointed out that closed mindedness of most sorts is bad ("homosexuality is always wrong!" or "Homosexuality is always a 'lifestyle' choice and should never be called a defect!")

      --
      Sometimes it's best to just let stupid people be stupid.
    17. Re:Some things are good some are bad by tempest303 · · Score: 2

      Even that noble goal is a slippery slope to tread. What diseases do we screen for? Cancer? Diabetes? Sickle Cell? ADD? Psoriosis? Dandruff? Halitosis?

      What SHOULDN'T we screen for? If it's possible to screen for all of those things, hell, why not? They're not desirable traits, that's for sure. This isn't the same as aborting fetuses, it's *screening eggs*. So once again, why not? Where's the harm?

      I think what you're getting at is that this will inspire a discrimination of people who currently have some diseases like what you list above. I can see where you're coming from on that, but I don't believe the 2 go hand in hand. We recognize that some people are born with negative traits, fine. But if we can help eliminate unnecessary hindrances like ADD, or even halitosis, why shouldn't we? Are these things that we need to protect somehow?

    18. Re:Some things are good some are bad by SoLoatWork · · Score: 1

      all of the above!

    19. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      Good points. I hope some clueful moderators read it.

    20. Re:Some things are good some are bad by Maryck · · Score: 1

      If you've ever watched the Coda in the extras section of the Gattaca DVD, you might get a partial answer to this.

      The gist of it is that, historyically, there have been tons of significant people (Abe Lincoln, Stephen Hawkings, etc) who would never have been allowed to exist because of a genetic predisposition towards certain diseases. Is this a good reason to swear off pre-birth selection completely? Probably not, but it is an important thing to consider.

    21. Re:Some things are good some are bad by chinton · · Score: 2
      I think what you're getting at is that this will inspire a discrimination of people who currently have some diseases like what you list above. I can see where you're coming from on that, but I don't believe the 2 go hand in hand.

      That is what I was leaning toward, but in the world we live in now, the two things do go hand-in-hand. The other issue is, how far from screening for diseases to screening for differences?

    22. Re:Some things are good some are bad by Mr.+Slippery · · Score: 1
      genetic based (where your sexual attraction mechanism is backwards)...there is no question that it is a genetic defect to be attracted to the wrong sex (I mean, duh).

      Uh, what do you mean by "wrong"?

      Your assertatoin that there's "no question" that this is a defect is simply false.

      Once again it has to be pointed out that closed mindedness of most sorts is bad

      Such as labelling someone else's choice of lovers - for whatever reason - as "wrong"?

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    23. Re:Some things are good some are bad by Ubergrendle · · Score: 1

      So you saw Gattaca too... As for the 6 fingers, wouldn't it be easier to develop a non-QWERTY, user friendly keyboard instead?

      --
      John Maynard Keynes: "When the facts change, I change my mind. What do you do?"
    24. Re:Some things are good some are bad by blowhole · · Score: 2

      Wow that was actually a very good argument. Mind if I quote you? Was that original thought or are you paraphrasing someone else?

      Note: this is NOT sarcasm. It's just so hard to agree with someone on /. without sounding like a sarcastic ass!

      --
      "Ask me about Loom"
    25. Re:Some things are good some are bad by jred · · Score: 1

      I'll put my vote in for halitosis... :)

      --

      jred
      I'm not a mechanic but I play one in my garage...
    26. Re:Some things are good some are bad by Reality+Master+101 · · Score: 2

      Mind if I quote you? Was that original thought or are you paraphrasing someone else?

      My own humble thoughts. Feel free to quote me: I'm all in favor of removing politics from this issue and bringing reasonableness.

      --
      Sometimes it's best to just let stupid people be stupid.
    27. Re:Some things are good some are bad by mjh · · Score: 2
      We'll create a better class of geeks! Or at least ones with 6 fingers (better keyboarding) or a mousing hand or something.
      Geez, if we're going to create a better class of geek, let's at least give him 2^n fingers. So 4 fingers or 8 fingers (per hand) and how much easier does counting in binary get for this person?
      --
      Key to financial independence: Spend less than you earn. Save and invest the difference. Do it for a long time.
    28. Re:Some things are good some are bad by Reality+Master+101 · · Score: 2

      Uh, what do you mean by "wrong"? Your assertatoin that there's "no question" that this is a defect is simply false.

      The purpose (think about that word before jerking knee) of sex is procreation. That there is a recreational and pleasurable aspect to sex is purely a side-effect: it's only to encourage the behavior. We are genetically programmed to find the opposite sex attractive, in order to continue the species (hopefully you don't think that man-woman attraction is societal conditioning). If that mechanism is somehow switched around so that we are attracted to the same sex, obviously that doesn't bode well for continuing the species.

      If a function of the brain is not operating in the way it was intended (i.e., attraction to the same sex), then it's a defect. Note that there is no moral component to this: it's simply factual.

      Such as labelling someone else's choice of lovers - for whatever reason - as "wrong"?

      You used the word "wrong" here in the sense of moral right and wrong, which is not the way I used it. Morality is irrelevent to this issue -- to either side.

      --
      Sometimes it's best to just let stupid people be stupid.
    29. Re:Some things are good some are bad by Engine · · Score: 1

      Is it the disease that made them great? Otherwise the argument is faulty. The same proportion of healthy people are significant as among them with deseases. Think of all the great healthy geniuses that will not be born because we choose to give birth to an unscreaned child with the possibility of predisposition towards certain diseases.

      (I hope that makes sence. I can garantee the thought was good. I am a bit crippled by my bad english)

    30. Re:Some things are good some are bad by dobber · · Score: 1

      I agree. As someone who codes for a living -- in large systems, when you change one tiny piece of code in a core system, you often have no idea of the subtle changes that you may have unleashed.

      DNA is our core. When we start mucking with it, the effects really can't be analyzed. Who knows what kind of functionality we are erasing/introducing.

      When I read "Brave New World" in high school, I thought to myself, "Who would ever think this way?" Well, we're getting there. And we don't even understand what we are doing.

      --
      "If you fight, fight without fear. If you love, love without reservation." -- J. Michael Straczynski, Babylon 5
    31. Re:Some things are good some are bad by jcgresham · · Score: 0

      Henri deToulouse-Lautrec is a perfect example; do we really want a homogenized world where we are free from disfunction? Guess this could make religion obsolete!

      from http://www.sandiegomuseum.org/lautrec/lautrec.html

      "His early years were spent on family estates near Albi, with Paris becoming his home in 1872. The victim of a genetic bone condition that made him vulnerable to fractures, he walked with a cane by age thirteen and grew to be only four feet eleven inches tall. Always of frail health, his adulthood was marred by his physical handicaps and also by alcoholism. Yet during his brief life he managed to create his own immediately recognizable style, and to evoke in his inimitable way a world full of gaiety and humor."

    32. Re:Some things are good some are bad by dalinian · · Score: 1

      Even if involuntary human suffering leads to great achievements, it still should be minimized. Would say Nietzsche have chosen to go mad, if he had had the choice?

    33. Re:Some things are good some are bad by aengblom · · Score: 2, Interesting

      Just to through a kink in your argument that homosexuality is a defect. True, it is one in terms of individual evolution, but you dismiss a broader "species" effect. Perhaps homosexual couples provide a certain benefit to traditional or modern society.
      For example there is species based reason why women can no longer have children after a certain age. Not only would pregnancy be difficult on the older mother, but older women (and men) can provide help to raise others' young children who are probably healthier. In the case of grandchildren, there is a point at which the gain in terms of having mroe kids is less than if an older person just helps their grandchildren.

      --


      So close and yet so far from the world's perfect ID number
    34. Re:Some things are good some are bad by Tackhead · · Score: 4, Interesting
      > Uh, what do you mean by "wrong"?

      He means it's a "defect" in the evolutionary sense. That people who are sexually attracted to the same sex are likely not to reproduce.

      His "duh" for gene-based homosexuality arises from the fact that an individual carrying such a trait is likely not have offspring, and that consequently, such genes render such individuals evolutionarily unfit.

      His "wrong sex" was intended similarly; in most species (that is, excepting certain hermaphroditic species where androgynous individuals "become" female upon receipt of sperm excepted), the "right sex" for purposes of propagating one's genes is the opposite sex.

      No judgement on moral fitness was passed. Only a judgement on evolutionary fitness. The two things are not the same.

      Likewise, as a heterosexual male who Doesn't Want Children (my idea of "fun" is babysitting a newly-overclocked Athlon XP 2000+ for a few months, then upgrading it to something faster, rather than spending 18 years plugging data into a newly-fabbed homo sapiens :-).

      If there's a genetic component to not having a paternal instinct, I carry it. That is, I am evolutionarily "unfit", my instincts are evolutionarily "wrong", because I have chosen to have certain bits of my anatomy snipped to ensure that (barring a serious upfuck on the part of the surgeon) I'll die without propagating my genes.

      (In any case, it's a moot point now, as homosexuals and childfree heterosexuals can now pass on their genes by donating eggs or sperm and fertilizing in vitro. But evolution never anticipated primates with brains big enough to pull off stunts like that ;-)

    35. Re:Some things are good some are bad by Tackhead · · Score: 1
      > I'm willing to bet that most people consider ugliness a disease. Look around you, there are more "cures" for ugliness than there are for anything else.

      "Money. I make lots and lots of money!" ;-)

    36. Re:Some things are good some are bad by GileadGreene · · Score: 1
      "Yet during his brief life he managed to create his own immediately recognizable style, and to evoke in his inimitable way a world full of gaiety and humor."

      That's great. But do you think he would have traded it for the chance to have normal bones and a healthy body? Would you be willing to take on some form of debilitating disease in exchange for artistic or musical greatness? Think long and hard about whta having that disease would actually mean to your life before you answer.

    37. Re:Some things are good some are bad by Maryck · · Score: 1

      Interesting argument. I think in some cases it was the disease, or at least the effort required to overcome it that made the person successful.

      Of course if you want to take the argument a step further, at what point do you actually declare a person acceptibly healthy? In other words, if a person has a 50% chance of early alzheimers, but otherwise will be a mathematical prodigy, should they be ruled out just because of that 50% chance?

    38. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      AIDS is nature's fag screener, we don't need to worry about that one.

    39. Re:Some things are good some are bad by tempest303 · · Score: 2

      That is what I was leaning toward, but in the world we live in now, the two things do go hand-in-hand.

      This I'm not going to touch, as it's more a fundamental belief than anything debatable on /. so I'm not going to touch this one, sufficing to say "I disagree."

      The other issue is, how far from screening for diseases to screening for differences?"

      Hrm... Well, I could see legislation to this effect as being appropriate and probably defective. Allowing for the screening only of medically defined diseases might be one way to go. But I think it's a huge mistake to not explore these avenues. Isn't prevention far far better than cures?

    40. Re:Some things are good some are bad by Reality+Master+101 · · Score: 3, Insightful

      Perhaps homosexual couples provide a certain benefit to traditional or modern society.

      It's possible, but it's hard to dismiss the historical animus towards homosexuality in almost every culture (I'm sure there are exceptions to this). If evolution truly favored homosexuality, then it would make sense that societies would tend to evolve toward accepting the benefits of it.

      I'm willing to accept the possibility that there might be some subtle purpose to the attraction mechanism getting switched around, but at this point that seems more political "happy science" than real science.

      --
      Sometimes it's best to just let stupid people be stupid.
    41. Re:Some things are good some are bad by LordNimon · · Score: 1
      I understand that, but one day our society will stagnate because no one is willing to put up with a disability, and then what do we do?

      Humanity grows only by overcoming its limitations. If humans no longer have any limitations, then they will stop growing. Our history has been full of individuals making sacrifices for the greater good, even against their own wishes. I see this as being no different.

      --
      And the men who hold high places must be the ones who start
      To mold a new reality... closer to the heart
    42. Re:Some things are good some are bad by zaffir · · Score: 1

      Not true. Humans, and animals in general, don't seek out a mate that is unique or different - if we did that, we'd all want to date cerebral paulsy(sp?) sufferers - they certainly stand out from the crowd. What we look for is the person with the traits we'd like in a child. Hundreds of years ago, the fatter a woman became, the more beautiful she was. Why? Because back then, starvation was a big worry. Someone who was very heavy most certainly didn't have trouble with a lack of nutrition (or so they thought). In today's society, people who are overweight are looked down upon - we assume they are that way because they sit around on the couch all day - that makes them weak. We assume they stuff their faces 24/7 - their self control is lacking. Since starvation is no longer a concern, we have turned towards another trait - strength. I hope that makes sense, otherwise, its just the cold medicine talking...

      --
      "Upon attaching the waterblock to my penis, I began to notice that I know nothing about computers." -- JRockway
    43. Re:Some things are good some are bad by maxpublic · · Score: 3, Insightful

      Spoken like a true moralist. You're willing - nay, eager - to inflict treatable genetic illnesses upon future generations just to satisfy your own personal beliefs on how the world should be. How ethical of you.

      But there's a solution: how about you butt out of the personal business of parents choosing to have children in whatever fashion they think is best, and we'll allow you to have children purely through the 'crapshoot' method. Then you can be content in the knowledge that at least you're doing your part to spur on creativity.

      Max

      --
      My god carries a hammer. Your god died nailed to a tree. Any questions?
    44. Re:Some things are good some are bad by maxpublic · · Score: 2

      I find it rather interesting that you define two classes of sexuality: heterosexuality and homosexuality. However, according to Kinsey and every relevant study conducted after him, there are *three times* as many bisexuals walking the planet as homosexuals.

      So, how can bisexuality possibly be classed as a defect? After all, you're just as likely to, and as capable of, reproducing as any straight person. Being bisexual doesn't reduce the chance of passing on genes to the next generation, which is apparently your sole criteria for determing 'defect' status in sexuality.

      By your own standards, bisexuality would be no more defective than heterosexuality.

      Max

      --
      My god carries a hammer. Your god died nailed to a tree. Any questions?
    45. Re:Some things are good some are bad by tgibbs · · Score: 1
      Many of the world's greatest artists, writers, and musicians had genetic "defects" of some kind. For these people, their problems are what drove them to greatness.
      Perhaps. Or maybe that is just another "just-so story" that we tell ourselves to console ourselves for misfortunes that we couldn't do anything about before now. In fact, we have no idea whether great men were great because of--or in spite of--their defects.
    46. Re:Some things are good some are bad by Reality+Master+101 · · Score: 2

      I find it rather interesting that you define two classes of sexuality: heterosexuality and homosexuality.

      Actually, I defined two different classes of homosexuality, which is important.

      However, according to Kinsey and every relevant study conducted after him, there are *three times* as many bisexuals walking the planet as homosexuals.

      Well, feel free to save toilet paper by using Kinsey. But let's say that that's the number. Either there is genetic bisexuality, or it would be psychological bisexuality.

      I didn't really cover bisexuality because I didn't think it was all that relevent, but it's possible to have a genetic bisexuality where the attraction mechanism is either totally off or on for both sexes. If this was the case, it would still be a defect.

      I have no particular evidence, but my gut feeling is that most bisexuality is psychological. That is, most people who are bisexual override their natural inclination by wanting to try "something different".

      The whole subject is extremely complex, and it will be very difficult to know what percentage of anything is genetically based or psychologically based until we've really isolated the cause of brain-based homosexuality. The point is that any genetic flaws that cause the attraction mechanism to not work in a way that encourages reproduction is most likely a defect.

      --
      Sometimes it's best to just let stupid people be stupid.
    47. Re:Some things are good some are bad by junkgrep · · Score: 1

      ---If evolution truly favored homosexuality, then it would make sense that societies would tend to evolve toward accepting the benefits of it.---

      This claim is nonsense. Evolution does not have foresight, intention, or even a permanent direction, and the "evolution" of culture is not necessarily in any way related to biological "evolution."

      ---I'm willing to accept the possibility that there might be some subtle purpose to the attraction mechanism getting switched around, but at this point that seems more political "happy science" than real science.---

      There is no simple "attraction mechanism." Animal life, including humans, show a full range of sexual behaviors. Maybe this is good for survival, maybe it is not. Neither you nor I really know, certainly not for each and every case. But trying to pretend that survival is the only "objective" end is just nonsense.

    48. Re:Some things are good some are bad by NoBeardPete · · Score: 1

      If you are going to pull out the evolutionary card, and start arguing about genetic programming, at least get things right. One of the purposes of sex is procreation. As long as an individual does successfully procreate, from an evolutionary point of view, there are no problems with having additional sex with whomever you want.

      Bonobos are a close relative of the chimp. They have _massive_ amounts of sex, between males and males, females and females, males and females, children and adults. They have threesomes and orgies. They use every orifice, and all manner of positions. They are doing fine, evolutionarily.

      For the bonobo, sex has many uses. One is to procreate, and that is an important one. However, sex is also used to cement relationships, make up after a fight, demonstrate dominance or submission, or just (apparently) for fun. In stark contrast to normal chimps, bonobos are peaceful and friendly, and almost never get into physically violent conflicts.

      Many other species also have common homosexual encounters. Dolphins, for one, commonly have homosexual sex. I could go on listing species for which homosexual acts are common, but I won't.

      The important thing for these species is that, while they do have homosexual sex, they also manage to procreate. For all of the non-human species, this means they must, at least every once in a while, have straight intercourse. Plenty of humans who are strictly homosexual manage to have children, either by planning a one-shot heterosexual encounter, by using the good old turkey baster, going to a fertility clinic, or whatever.

      Not every sex act has to be intended to cause procreation. In fact, most people try to deliberately avoid conception most of the time they have sex. So as long as a gay person does manage to have a child somehow, somewhere, sometime, I don't think it really matters who they are attracted to, or who they screw the rest of the time. And it is becoming increasingly easy, technologically and culturally, for gay people to have children, so the issues you cite will continue to become less and less relevant.

      In short, you don't have a leg to stand on.

      --
      Arrr, it be the infamous pirate, No Beard Pete!
    49. Re:Some things are good some are bad by junkgrep · · Score: 1

      ---The purpose (think about that word before jerking knee) of sex is procreation.---

      Taking purposeful direction from the way nature is the genetic fallacy: turning is into ought. Our genetic makeup is not the result of any purposeful intention that homosexuality is somehow thwarting.

      ---If that mechanism is somehow switched around so that we are attracted to the same sex, obviously that doesn't bode well for continuing the species.---

      So far, having a minority of the population be homosexual doesn't seem to have hurt our species, or other species that have homosexuals. Plenty of species actually benefit from having certain members of a cooperative group specialize in breeding, and other non-breeding members play other roles (ants, for instance). It's not necessary for every individual to strive to pass on its genes: sometimes genes survive best via having strong kin groups which support the next generation.

      ---If a function of the brain is not operating in the way it was intended (i.e., attraction to the same sex), then it's a defect. Note that there is no moral component to this: it's simply factual.---

      No. Calling it a defect implies that there was something "intending" humans to be a certain way, and homosexuality is a deviation from that intention. But evolution does not have intentions. There is no "correct" configuration for a human being. You may not mean any moral component to attach, but your reasoning is just as flawed as if there was.
      What you are doing is trying to argue "purpose" or "defect" as if these were objcetive terms. They are not: they both simply compare the state of an example to an pre-specified ideal. But the selection of the particular ideal is subjective, not objective.

    50. Re:Some things are good some are bad by Chaswell · · Score: 1

      I see you argument, but I really think it may be what we tell ourselves to feel better about the less fortunate. If we remove a level defects, don't you think we may find new challenges and have an opportunity to rise to new levels?

    51. Re:Some things are good some are bad by Atrahasis · · Score: 1
      but it's hard to dismiss the historical animus towards homosexuality in almost every culture (I'm sure there are exceptions to this)
      How about ancient Greece, where Plato, one of the fathers of all that we hold to be good philosophy, had entire dialogues on why it was a good thing?

      You claim that morality has no place here, yet you use the word defect - which in itself means falling short of perfection. Who defines perfection? As the saying goes, nobody's perfect, so I guess we're going to be selecting out 100% of the embryos. That seems to me to be more detrimental to the continuance of the species than homosexuality.

      PS - Was your use of the word animus a play on words or was it not that clever?

    52. Re:Some things are good some are bad by pavese · · Score: 1

      Houellebecq has written a nice book about this subject... Elemental particles it was called i think.

      I for myself am sure I wouldn't be able to handle a healthy body. I'd start using drugs or get depressed because you see all this suffering around you, etc etc.
      No pain no gain... No happyness without drawbacks.

      I'd say "society will stagnate" is positive rather then negative tho. And already happening to some extend in developed countries... The downside is there are still too many clewless ppl fucking around :P

    53. Re:Some things are good some are bad by pavese · · Score: 1

      Hmm that elemental particles was quite a nice read actually... here is it on amazon:

      http://www.amazon.com/exec/obidos/ASIN/037572701 9/ qid=1014857901/sr=8-1/ref=sr_8_3_1/002-3856901-210 3223

    54. Re:Some things are good some are bad by cappadocius · · Score: 1
      having six-fingers is a dominant gene.

      No. Seriously.

      --

      omnia tua castra sunt nobis

    55. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      Plenty of species actually benefit from having certain members of a cooperative group specialize in breeding, and other non-breeding members play other roles (ants, for instance). It's not necessary for every individual to strive to pass on its genes: sometimes genes survive best via having strong kin groups which support the next generation.

      This is worth repeating simply because you hit the nail right on the head. But I feel I should mention that individuals can and do pass on their genes without procreating. They do that by helping others (usually relatives) with similar genes procreate.

      And oddly enough, to some extent the homosexual movement has done that. As taboos regarding sex get broken down, people tend to have more sex, both homosexual and heterosexual.

    56. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      We simply *dont* know what all of our genes do or how they behave in specific combinations and under specific conditions. There are just so many possibilities that total prediction and total control is not possible.


      Very very true. But Gattaca et. al. presumed that 90, 95, 99% of the population would subscribe to the same concept of the perfect person. If only 10% of the population screened out Sickle-Cell anemea, and another 10% screened out Alzheimers, another 10% screened out some other "defect", and say 50% screened out nothing, we'd quickly find out which of these diseases actually do have the beneficial effects you speak about. Ultimately that's why perhaps the smartest thing to do is let each person choose for him/herself whether or not to genetically select his/her child. Personally, I'm going to do it the old fashioned way, but as long as there aren't written or unwritten laws forcing people to do it one way or the other, the human race will become stronger because of it.

    57. Re:Some things are good some are bad by junkgrep · · Score: 1

      ---But I feel I should mention that individuals can and do pass on their genes without procreating. They do that by helping others (usually relatives) with similar genes procreate.---

      Actually, this is just what I was reffering to. E.O. Wilson put this idea forward in his Sociobiology book: that homosexuality might actually be a useful trait to have in a line that expresses itself occasionally. Of course, Wilson makes the argument that homosexuals might on average be more altruistic than heterosexuals, but as far as I know there is no support for this claim being a genetic factor, as opposed to merely a cultural one.

    58. Re:Some things are good some are bad by zmooc · · Score: 2
      Have you ever fallen in love with a person you've chosen in a rational way? I haven't and I can't. Let's just assume nobody can (let me know if you can!:)); then I don't see how homosexuality could possibly be psychological. I also think most real heterosexual persons consider people of the same sex just plain disgusting in exactly the same way they consider people of the other sex attractive. So I think those "pshychological homosexuals" are in fact normal bisexuals.

      One other point your post made me think of: homosexuality is rather omnipresent in our society and is probably incluencing the way it works in ways we may not even understand. So therefore the impact of "taking it away" by genetical selection may be different than we might expect. The Alzheimer case PROBABLY doesn't influence social aspects and is therefore probably a lot safer.

      And one more point: if homosexuality is genetical, why does it still exist when they cannot reproduce? (does anybody have facts on this?)

      DISCLAIMER: I'm bisexual:)

      --
      0x or or snor perron?!
    59. Re:Some things are good some are bad by Vagary · · Score: 1

      You make two assumptions:

      1. The world would be worse without homosexuals. Now I'm prepared to agree that the world would not be better, but it is not obvious that it would be somehow lacking.
      2. It is possible to screen for genetic homosexuality. Most evidence suggests that homosexuality is caused by such a complex set of genes that it would be much harder to identify than a mere genetically inherited disease.
    60. Re:Some things are good some are bad by slubberdegullion · · Score: 1

      You know, the great thing about binary is it can be represented with anything that can be in two positions. Such as, for instance, your fingers. By representing binary series of 1s and 0s on your fingers(100110 becomes left thumb up, right pinky down, right ring finger down, right middle finger up, right index finger up, right thumb down), you can count up to 1023. This method of counting uses every possible combination of up and down fingers. Of course, a person with 8 fingers per hand could count to 65535, but withing reasonable limits of counting your 5 fingers are more than sufficient.

    61. Re:Some things are good some are bad by Richthofen80 · · Score: 1

      Of course the ability to screen is related to the financial status. Doctors don't work for free, because working for free is slavery... and doctors wouldn't put in the time / effort it takes for a smile. And the equipment and such is very expensive... so are the facilities. The idea that doctors shouldn't discriminate against people who can pay versus people who can't is ridiculous. so is the notion that doctors should work regardless of whether the patient can pay... thats selective slavery. I realize you didn't directly say it, but I think that's what your hinting at.

      My first concern is that you fail to see that *everything* is divided into class. Right now, those with better finacial status eat better tasting, more expensive foods, wear designer clothes to set them apart, send their kids to private well funded schools, and give them every advantage they can. Screening them for disease only means these rich people will live longer , too. Basically, people will draw inferences from those who've been screened and later gm'ed, but what inferences are these? that their parents had money and decided to screen? not much... i mean, traditional racial discrimination is way worse than any GM discrimination... aren't americans still bullheadedly thinking irish people are all drunks and asians are all math whizzes?

      Its not a matter of class, its a matter of intelligence... Babies cost money. Probably more than they did 50 years ago. The truth is, any adult who's had a physical and has half a brain knows what traits they may pass on to their kids. So the issue is will the adult wait patiently, save the money needed for the test, and go without some things in order to insure a healthy baby? If so, these adults will probably raise a kid that will do real well, assuming they pass on the common sense and patience to their kids. Actually, most people who plan well and save and go without unnecessary things end up having a decent amount of money in the end anyways.

      Screening is less a financial issue than a lot of people think... it will probably become very cheap if the government doesn't regulate it to all hell. Very cheap still may mean $10,000 , but if you don't have at least that much saved, what are you doing having kids? I mean, people who'd want to screen are obviously planning their pregnancies... shouldn't they plan financially and cover the costs, too?

      --
      Reason, free market capitalism, and individualism
    62. Re:Some things are good some are bad by epukinsk · · Score: 2

      For genetic based homosexulity, there is no question that it is a genetic defect to be attracted to the wrong sex (I mean, duh)...if it were possible to screen my sperm or my wife's egg for the defect, I would certainly do it.

      Would you screen your zygotes for the kind of personality that would get them picked on in school? Would you want to prevent them from ever beind dumped?

      What you're talking about is denying your child experience. Being gay is not a defect, it's a part of a person's identity and it's as much a blessing as a curse--just like any other facet of someone's identity. Yes, gay men are uninterested in impregnating women. Impregnating women is hardly the center of any man's existence in these times. Raising children, spending time with friends, falling in love, pursuing challenges--these are the bread and butter of human life, not shooting your sperm into a fertile woman.

      I'm as straight as anyone, but I don't think it's my place to say my child's life would be better if they were not gay. It's not my choice to make, and the repercussions of my choice are not something I can pin down easily as "homosexuality is a defect". As a parent, it's not my job to deny my child experience, it's to supply them with love and support.

      -Erik

    63. Re:Some things are good some are bad by slubberdegullion · · Score: 1

      lack of obeying authority.
      I don't think that many people find this undesirable. It would be screened out only if the government was in control, which would mean a totalitarianism anyway.

      Anyway, do you really think that the world would be a worse place if everyone were smart, good looking and free of disease? It's not as if we aren't already improving ourselves--plastic surgery and medicine have accomplished much in the way of your evil totalitarian playing god. It is no longer considered appropriate to let someone with a terrible disease die. Maybe tomorrow these 'doctors' will be controlling our thoughts!

    64. Re:Some things are good some are bad by CynicTheHedgehog · · Score: 1

      I always figured people were bisexual because they wanted to increase their odds of having sex...

    65. Re:Some things are good some are bad by balthan · · Score: 1

      And one more point: if homosexuality is genetical, why does it still exist when they cannot reproduce? (does anybody have facts on this?)

      So homosexuals never marry and have kids in an attempt to appear "normal?" Also, if it's a recessive gene, it could be passed along by hetrosexuals.

    66. Re:Some things are good some are bad by Dyolf+Knip · · Score: 2
      So I should not screen my children for the sake of letting them enjoy the experience of cancer? Or Alzheimers? Or heart disease? I'm sure that people genetically predisposed for being used car salesmen are having some fascinating experiences, but that doesn't mean it's one I want my kids to share.

      Basically I mean that using this argument either way is pointless. It is just as much an experience to be in the Special Olympics as it is to formulate ground breaking theories in physics.

      --
      Dyolf Knip
    67. Re:Some things are good some are bad by Dyolf+Knip · · Score: 2
      Fortunately, a culture in which people value women as a scarce resource yet don't want to be the one to have to raise a baby girl will have to change its ways or quickly become extinct. Problem solves itself.

      For the rest, how much of this is different from parents raising their children in a certain way? It's quite amazing the degree to which parents can shape a child's future, yet there is no qualifying test to have kids. Bigots, murderers, selfish megalomaniacs, a whole panoply of unpleasantness can be found among those would be 'Mom and Dad' to someone. Yet few would dream of setting standards for those wishing to become parents. How is this different?

      --
      Dyolf Knip
    68. Re:Some things are good some are bad by 3nd3r · · Score: 0

      Well I have to say that you are correct in a sense, but people will always find some way to make others or themselves feel inferior and then go on to rise to greatness from said experience. So in effect not having a physical/mental issue wouldn't change much except people would be more aesthetically beautiful...

    69. Re:Some things are good some are bad by maxpublic · · Score: 3, Insightful

      Well, I'll be goddamned. I posted a rather lengthy response to this and it was deleted. It showed when I submitted, but here I am four hours later and now it's gone. No message, nothing - just gone.

      Well, let's not let a little thing like that stand in the way of pig-headed persistence. Once again into the breach.

      Well, feel free to save toilet paper by using Kinsey.

      Please post a link to an empirical study published in an accredited, peer-reviewed journal which definitively refutes the numbers presented by Kinsey, and all who came after him confirming those numbers. Keep in mind the words "empirical", "accredited", and "peer-reviewed" when considering which link is best suited to support your assertion that when it comes to the ratio of bisexuals to homosexuals, the man and his team had their heads up their asses.

      If this was the case, it would still be a defect.

      Your definition of 'defect' goes far beyond the traditional definition used in biology and genetics. In fact, it seems to encompass anything which you, personally, don't particularly care for.

      In order for a trait to be a defect - as defined by the biological sciences - it must in some fashion reduce the organisms chances of survival or probability of successfully reproducing. Bisexuality does neither; bisexuals aren't less likely to survive nor are they less likely to reproduce. There is no defect here, at least so far as the word is defined in the traditional scientific sense.

      my gut feeling is that most bisexuality is psychological.

      Your gut feeling and two bucks will get you a cup of coffee.

      That is, most people who are bisexual override their natural inclination by wanting to try "something different".

      My own experiences are purely anecdotal but rather wide-ranging, primarily because I am bisexual and I've had contact with hundreds of bisexuals over the course of my lifetime. Their accounts concerning their bisexuality directly contradict your 'gut feeling'. As you have no evidence whatsoever to support your rather whimsical claims, I'll take the word of several hundred bisexuals - people in a position to know what motivates them - over your 'gut feeling' any day of the week.

      The point is that any genetic flaws that cause the attraction mechanism to not work in a way that encourages reproduction is most likely a defect.

      If you're of the opinion that sex is only useful for procreation and that the development of social ties through sex is of no survival value, I suggest you educate yourself on the topic before speaking further. This is a fundamental given of the social sciences, so clearly apparent that it isn't disputed. Claims to the contrary demonstrate nothing more than base ignorance, willful or otherwise.

      And once again this isn't the definition of defect used in the biological sciences.

      But even if we were silly enough to adopt your definition, I could claim that bisexuality gives an individual a survival advantage in that this person not only has the same chance of reproducing as a heterosexual, but that the bisexual would also be capable of strengthening social ties through sexual contact with members of the same gender in a way that heterosexuals couldn't duplicate. Since no serious social scientist would attempt to refute the claim that members of a group with strong social ties are more likely to survive and reproduce than members with weaker ties, it's apparent that in this case the bisexual has a better chance of survival than the heterosexual as long as all other members in the group aren't just heterosexual. And we already know that heterosexuality isn't universal.

      By your own definition the bisexual has a survival advantage over the heterosexual. In comparison to the bisexual, heterosexuality could actually be viewed as a defect.

      Which only goes to show just how silly your claims actually are.

      Max

      --
      My god carries a hammer. Your god died nailed to a tree. Any questions?
    70. Re:Some things are good some are bad by the+phantom · · Score: 2

      To continue the other respose, it could also be that a heterozygous homosexual/non-homosexual allele combination could have partial expression, or even more likely, homosexuality (if, indeed genetic -- I have no opion one way or the other, not enough knowledge to make any kind of judgement) is a polygenetic trait, i.e. several genes determine sexuality, not just one.

      Boy, I am having to dig up some OLD notes for this discussion ^_^

    71. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      do you want to have sex?

    72. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      please, do not compare homosexuality to a disease. why don't you just eliminate all genes that have to do with art? or music? or creativity in general?? how about the other extreme? eliminate all genes that make conservative people conservative? we need the balance.

    73. Re:Some things are good some are bad by the+phantom · · Score: 2


      (DISCLAIMER: I am trying to remain neutral here, please don't flame me for gay bashing or being a bleeding heart liberal.)

      Certainly, genetic homosexuality would be selected against by natural selection. At the same time, the greatest adaptive trait that HUMANS have over other species is CULTURE. Culture is a set of learned behaviors. Cultural traits that are maladaptive cease to exist. Traits that are adaptive are passed on. That means adaptive for society, not the idividual, as biological natural selection would assume.

      It is possible that cultural homosexuality is, in fact, adaptive. To make the argument, I am going to bring up another scenario:

      Let us assume that biological selection is the only force determining traits. In that situation, any person would want to have as many children as possible, thus increasing the chance that their children will survive to pass on their genes. This would lead to overpopulation very quickly, then the population would stabilize through time.

      However, there is a very high correlation between cultures with very low protien diets and long post-partem sex taboos (no sex for at least one year after giving birth). In a purly biologically driven system of natural selection, you would expect mothers to give birth as often as possible, then have the men go out and kill/steal/coerce as many animals from neighbors as possible to feed the children. The taboo likely developed as a societal restraint on over taxing the resources available for the good of the community.

      Cultural homosexuality could very well have similar root. Not having children keeps the population down, thus reducing the risk of overpopulation.

      (This explaination is based on the theory of cultural ecology, i.e. culture adapts to its environment. It has limited application, especially in modernized societies. I am just tossing it out as a theory -- I don't particularly believe it myself, so take it for what it is worth: yet another perspective to add to the tapestry of lively, gentlemenly debate.)

    74. Re:Some things are good some are bad by sudog · · Score: 2, Insightful

      You don't know what you're talking about. There are plenty of evolved genetic traits that at first don't appear to be beneficial to survival but turn out to be quite ingenius.

      Perhaps there is a component of homosexuality which actually *does* contribute to genetic propagation? Are you a scientist who has studied it for the better part of your life or are you basing your conjecture purely on what you imagine is logical?

      Think about it this way: If it wasn't in some way beneficial, or a side effect of something else that is beneficial, then after the millions of years we've all been evolving they would have bred themselves completely out of the equation a VERY long time ago.

      In a later note you imply it only takes 10,000 years to build a genetic immunity to smallpox. How about millions of years of evolution versus the sizable percentage of the population that is homosexual? How can you possibly conclude that homosexuality is counter-productive when the evidence (ie: their survival throughout the eons) is so obviously to the contrary?

      You don't honestly think this is a recent mutation do you?

      Thus, your "logic" (if it can be called that) is non-sequiteur and you need to go back to whatever course you think you learned evolutionary psychology or biological determinism from.

      *bzzzt* Try again hotshot.

    75. Re:Some things are good some are bad by sudog · · Score: 1

      Somebody please mod parent up. 2 is far too low a score to be assigning to this well-written spank-down! :)

    76. Re:Some things are good some are bad by skilef · · Score: 1

      There are some kinky toads you might be interested in: bisexually reproducing triploid toads.. It's not the same as homosexual organisms, but you could speak of a potential evolutionary inhibiting factor here..
      Who can argue with mother nature?!?

      --

      You do not exist. Go away.
    77. Re:Some things are good some are bad by madmag · · Score: 0

      I find it rather interesting that you define two classes of sexuality: heterosexuality and homosexuality.

      What about the sexuality I am going through at the moment? Its called "NoNosexuality".

      Everywhere I ask I get the answer "No" , "No".

      --


      --
      If Microsoft is the solution, I want my problems back
    78. Re:Some things are good some are bad by Anonymous Coward · · Score: 0

      He means it's a "defect" in the evolutionary sense. That people who are sexually attracted to the same sex are likely not to reproduce.

      So? Simply because a trait does not increase the individual's chances of survival, doesn't mean it is a "defect." Take breeder tadpoles for example... They never live to reproduce, they are eaten as sustenance by other tadpoles. But their existence is an evolutionary solution to the problem of ensuring the next generation of frogs has a supply of food. It's entirely possible that the complex social evolution of humans has lead to homosexuality being selected for in a certain percentage of the human gene pool. Possibly as a solution to overpopulation, or perhaps there is another benefit to human communities that have homosexual members as opposed to those that do not. This has been suggested in anthropological literature. Regardless, your treatment of the matter is simplistic, at best.

    79. Re:Some things are good some are bad by zmooc · · Score: 2

      Well...there are also a lot of homosexual animals which probably wouldn't "marry" because that's what they're pushed to do by the society because it's "normal" (or do they?). And if it were a recessive gene, shouldn't we find more homosexuals in certain families?

      --
      0x or or snor perron?!
    80. Re:Some things are good some are bad by Hittite+Creosote · · Score: 1

      It's not a matter of inheriting others DNA, just the 'best' of the two parents - so if a successful film director marries a star actress, they'll pay their private doctors to make sure the kids inherit his brains and her looks (rather than the other way around).

    81. Re:Some things are good some are bad by Mr.+Slippery · · Score: 1
      His "duh" for gene-based homosexuality arises from the fact that an individual carrying such a trait is likely not have offspring, and that consequently, such genes render such individuals evolutionarily unfit.

      Ah, but there's more to evolution than reproducing yourself. If, for example, there is a surplus of males, your genes are better off if you hook up with another guy and set your brother (who share a large chunk of your genome) up that that oh-so-evolutionarily-fit female, than if you and your brother kill each other fighting over the women.

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    82. Re:Some things are good some are bad by Mr.+Slippery · · Score: 1
      You make two assumptions:

      1.The world would be worse without homosexuals. Now I'm prepared to agree that the world would not be better, but it is not obvious that it would be somehow lacking.

      Would the world be "worse" without left-handed people? Blue-eyed people? People who prefer fat lovers to thin ones? Would it somehow be lacking, and if not does that mean we should eradicate lefties, etcetera, from the genome?

      Diversity is good.

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    83. Re:Some things are good some are bad by 4of12 · · Score: 2

      I don't think that many people find this undesirable.

      I don't know. There are more than a few friends of mine that are parents that would love to have their kids obey them.


      Maybe tomorrow these 'doctors' will be controlling our thoughts!

      You don't have to wait for a MaybeTomorrow.

      Prozac is here today.

      --
      "Provided by the management for your protection."
    84. Re:Some things are good some are bad by Kombat · · Score: 1
      The poor would go the 'natural' way and subbsequently become a lower class physically
      than families who can afford such procedures.


      But this is already happening. Those who can afford hair transplants, liposuction, and facelifts get an aesthetic advantage over those who can't. And look around - the world hasn't exactly fallen apart because of it.

      By your logic, we should eliminate all university fees, and have enrolment done via some sort of "lottery," to ensure that rich parents' kids don't get an advantage over those who can't afford school, or couldn't afford a private tutor through high school to help them score higher on the SATs.

      --
      Like woodworking? Build your own picture frames.
    85. Re:Some things are good some are bad by stienman · · Score: 2

      But this is already happening. Those who can afford hair transplants, liposuction, and facelifts get an aesthetic advantage over those who can't. And look around - the world hasn't exactly fallen apart because of it.


      The transplants, liposuction, facelifts, etc do not get passed down from generation to generation. I did not say that it wasn't happening, and who are you to say that the world isn't 'exactly' falling apart? I appreciate you sharing your opinion, but it's just your opinion - nothing more. I do not intend to suggest that the world is falling apart, either.

      By your logic, we should eliminate all university fees, and have enrolment done via some sort of "lottery," to ensure that rich parents' kids don't get an advantage over those who can't afford school, or couldn't afford a private tutor through high school to help them score higher on the SATs.

      My logic does not suggest any course of action. It simply states that this sort of preselection has a known result. I did not say that we live in a society now free of class distinctions, nor did I say that we should avoid this course of action because it may polarize those distinctions more. I said that it will be the outcome of genetic preselection, based on how societies changed under previous technological advancments available to the wealthy.

      I won't get into the whole argument about what we should put on the other side of the scale to balance things - if anything. That is a whole field which is not suited for discussion on this board. One thing can be said - So far, in our society, the innovations that at one time used to be available only to the rich trickle down so they are commonplace and affordable by the vast majority of the populace, which is somewhat different than many (but not all) previous empires.

      -Adam

    86. Re:Some things are good some are bad by Tackhead · · Score: 2
      > You don't know what you're talking about. There are plenty of evolved genetic traits that at first don't appear to be beneficial to survival but turn out to be quite ingenius.

      Actually, you (and others) raise a valid point, which I glossed over in my haste to say "Yo, he's not passing a moral judgement".

      Sickle cell anemia is a great example of one such trait. If there's lots of mosquitoes around, the defect's a survival benefit.

      Indeed, one can make the case that homosexuality is also such a trait -- somebody's gotta be "disconnected" from child-rearing to be the tribal shaman. (cf. various studies on what some early cultures did.) We've observed links between autism and geekiness, synesthesia and creativity, and homosexuality and creativity.

      To be absolutely accurate, I probably should have limited myself to saying that evolutionary fitness implies only that the incidence of genetically-induced homosexuality in a population will be self-limited.

    87. Re:Some things are good some are bad by epukinsk · · Score: 2

      I was suggesting that homosexuality is not in the same class as cancer, alzheimers, heart disease, and mental retardation. I pointed out that impregnating women is not the bread and butter of human existence.

      Cancer - that denies you life, which is the bread and butter of human existence

      Alzheimers - that denies you coherent thought, which is the bread and butter of human existence

      heart disease - slows you down, and kills you, see Cancer above.

      mental retardation - denies you intellectual equality with the bulk of the world. But I am unsure that that is really necessary for a full life. I'd put that in the gray area.

      Clearly there are many things which hamper a child's ability to live a full life. And I'm not suggesting that we shouldn't screen for those. I'm merely suggesting that homosexuality is not one of those things, and perhaps we needn't screen for it. By screening for it, we're limiting the diversity in life that makes life worth living.

      -Erik

    88. Re:Some things are good some are bad by Dyolf+Knip · · Score: 2

      Sure, remove the obviously bad stuff, keep the obviously good stuff. But what about the grey areas? Do we leave that choice up to the parents who will actually be raising the child or put it in the hands of some faceless bureaucracy? I can't even imagine the kind of nonsense they'd be likely to come up with. They'd also be busy being lobbied by indistries that would be hurt. For instance, getting rid of diabetes (Type I, at least) would be a Good Thing, right? Except there's good money being made in insulin production, money that would be lost if fewer people needed it. I would not put it past such a committee to do stuff like forbid screening for diabetes.

      --
      Dyolf Knip
    89. Re:Some things are good some are bad by Another+MacHack · · Score: 1

      Why not leave that decision to the parents, who will be morally and legally obligated to provide for that person for the first 18 or so years of their life?

  6. Re:I want to make a baby with Anna Paquin by delphin42 · · Score: 0, Offtopic

    you lose, sorry!!!

    --
    -- Adam
  7. Imagine the Possibilities by e1en0r · · Score: 0, Redundant

    If only they could screen for the Trolling gene. Troll Free /. in 50 years?

    1. Re:Imagine the Possibilities by e1en0r · · Score: 1

      Dammit, it wouldn't have been redundant if this little worm at work hadn't come over and wasted my time for 5 minutes. And now i'll probably get an off topic for this. All that hard karma work down the drain.

  8. More useful genes... by Anonymous Coward · · Score: 0

    Have the genes determining breast size been discovered yet?

    The world could only benefit from the female part of the population being exceedingly buxom and the male part never needing to wear bras.

    1. Re:More useful genes... by 8string · · Score: 1

      No, they have been searching in the wrong areola of the DNA sequence.

    2. Re:More useful genes... by Anonymous Coward · · Score: 0

      That was very punny, my friend. Maybe the will find the gene that prevents mammary loss.

  9. So far, not so bad by 0tim0 · · Score: 1
    I've got no problems for screening for dieases. It's when they start screening for eye color or height or male-pattern baldness I don't think it's such a good idea.


    --t

    1. Re:So far, not so bad by jgerman · · Score: 2

      Speak for yourself, those of us who are losing their hair see it differently, ease of hair care aside. ;)

      --
      I'm the big fish in the big pond bitch.
    2. Re:So far, not so bad by TheBigDinK · · Score: 1

      So you're saying you would rather have not been born? That's what would have happened in your case. Be proud of your genetic diversity! =)

    3. Re:So far, not so bad by susano_otter · · Score: 2

      Behold! One day, my parents had sex. No egg was fertilized. As a result, my sibling has never been born. How do you think my sibling feels about this?

      On another note, I've managed to inherit clinical depression from both of my parents. Am I proud of my genetic diversity? Fuck no. It's a huge pain in the ass, believe me. Besides, why should I be proud of my genes? It's not like I had anything to do with the planning or implementation of my beautiful green eyes; taking credit for them would be pretty tacky, don't you think?

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    4. Re:So far, not so bad by jgerman · · Score: 2

      Heh, allready thought of that. If I were a religious man it wouldn't matter, the shell would be different but the soul inside would still be the same. I'd still be me, but a me with hair ;)
      Of course it would be interesting to see how different I'd turn out. Of course who knows what other "defects" I would have, maybe I'd have huge ears, or wouldn't be able to fill out my boxers as well, or at all I coulda been a chick. I think I'll be happy with my genetics, if for different reasons than you suggest. :)

      --
      I'm the big fish in the big pond bitch.
    5. Re:So far, not so bad by jgerman · · Score: 2

      I was taking the opposite stance than this guy above but let me reverse things for a second. Proud may not be the word, but liking who you are is a pretty good idea, seeing as how there's nothing you can do to change it. Though people are proud of things that they have no control over all the time. I'm proud of my intelligence for instance.

      --
      I'm the big fish in the big pond bitch.
    6. Re:So far, not so bad by susano_otter · · Score: 2

      Oh, well if you mean "do I like who I am?", then by all means, yes! Depression, green eyes, and all, I wouldn't trade me for anybody else on earth :)

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    7. Re:So far, not so bad by spiro_killglance · · Score: 2


      Woa, hold up there on the contrafactuals.

      You are exactly the sum of all your experiences,
      and memories. If you hadn't have gone bald, you
      wouldn't be the you,that you are now, someone
      very similary possibly but not the same.

      The thing with contrafactuals (those objects and
      events that could have been but aren't), is that
      as soon as how change one thing, you have many
      other chooses that just weren't there before, e.g.
      If you weren't bald, how many grey hairs would you have?

      Give all the new possiblities, you can then try to
      "best match" one of them with you, to say, "that
      is what i want i would have been like if i
      hadn't gone bald", but even if such a best match
      exists, this in no way is a unique match.

    8. Re:So far, not so bad by caferace · · Score: 1
      Oh, well if you mean "do I like who I am?", then by all means, yes! Depression, green eyes, and all, I wouldn't trade me for anybody else on earth :)

      Hey Waittaminnit. You're me!

      You wouldn't happen to have a sister, wouldja? ;)

    9. Re:So far, not so bad by susano_otter · · Score: 2

      Two, in fact. But if I'm you, then who are you?

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    10. Re:So far, not so bad by caferace · · Score: 1
      But if I'm you, then who are you?

      OK, now that's depressing. Hmmm. Check with one of your sisters. Frankly, I'm baffled.

    11. Re:So far, not so bad by jgerman · · Score: 2
      That's a philisophical opinion, and not the argument I presented. Were I a christian, for one, I would believe that my soul is who I am, not the mortal body I walk around in. My soul would be the same regardless of the body that it inhabits.


      To move to your argument however, why stop there, I am not the same me I was when I wrote the original post, I'm not the same me now at this instant that I was when I wrote the above paragraph. I'm certainly not the same me when you read this. I am someone very similar, but not the same. However, there is a cohesive "I" that I imagine is me regardless that the makeup of me changes from instant to instant. Am I not me now? Am I not me twenty minutes from now. Would I not be me had, on the drive home, took a different route. Yes, at least I would believe that I'm me so I believe that had I not gone bald I would still be me.

      --
      I'm the big fish in the big pond bitch.
    12. Re:So far, not so bad by jgerman · · Score: 2

      Certainly, that's exactly the distinction I was trying to make verses pride, and what I believe the original poster was trying to get at. It's an interesting exercise though isn't it. I've wished I was someone else, but I invariably start adding: "but with this quality (that I presently have)", luckily I, and I'd assume most others would as well, come to the conclusion that percieved flaws and all I wouldn't want to be anyone else.

      --
      I'm the big fish in the big pond bitch.
    13. Re:So far, not so bad by Anonymous Coward · · Score: 0

      exactly! every single sperm should have a chance to fertilize. whoops, looks like we're going to need a bigger planet. our infrastructure is not big enough either. the entire internet will be slashdotted in about 15 years.

    14. Re:So far, not so bad by spiro_killglance · · Score: 2


      This is a late reply so probably no one will
      read it. But, i think my argument still applies
      if there is a soul, as long a soul is a stateful
      object that changes with time. After all in most
      religions souls pick up and lose sin or karma as they progress through time.

      I agree with your second paragraph, but the point
      is the cohesive I, you talk about is a best match across time, and this gets much more completical
      when you include contrafactuals or parallel
      universes.

  10. What else can be found by inerte · · Score: 1

    That interesting, and surely helped the woman. But I wonder what else can be found at this pre-screening stage.

    Not only the diseases, but when (and if) we can pre-screen for intelligence, strenght, certain characteristics, won't we be creating a 'super human-race'?

    1. Re:What else can be found by Bonker · · Score: 5, Insightful

      Not only the diseases, but when (and if) we can pre-screen for intelligence, strenght, certain characteristics, won't we be creating a 'super human-race'?

      Very simply, you can't screen for most human traits. Period. Sorry, go to the back of the line.

      Besides the fact that most traits are caused not by one gene, but by the interaction of dozens of genes and the proteins they create, you have to consider that almost all human traits develop in accordance to someone's environment.

      Thusly, if Albert Einstein had been raised in an environment where he wasn't exposed to mathematics or the written word until he was 30 years old, he probably wouldn't come across quite as bright as he was. If he had been raised in an environment where he was not exposed to speech-- The so called 'Forbidden Expirement'-- he probably would come across as being pretty retarded.

      If Michael Jordan had not had the opportunity to work hard in his youth and become athletic, he probably wouldn't be the sports superstar he is today. He couldn't just 'develop' those traits and skills later in life.

      Say you're an intelligent but pudgy software engineer/couch potato type and you actually manage to get the doctors to screen embryos and sperm most likely to create an athletic individual. If the child created may have a better chance of becoming atheltic, but if he follows his parents example, he will probably be just as pudgy.

      Now the one trait that you *can* screen for is gender, mostly because the relationship between X and Y chromosomes has been fairly well observed even if the science behind all the related protein interactions has not been fully plumbed yet.

      This raises some scary possibilities, especially in parts of the world where reproduction is controlled by government (China) or families are encouraged to have male children. (Quite a bit of the world, actually.) Having a gender imbalance will do a number on women's rights.

      --
      The next Slashdot story will be ready soon, but subscribers can beat the rush and slashdot the links early!
    2. Re:What else can be found by nil_null · · Score: 0

      You'd be surprised at how intelligence is more a product of what a person experiences after they are born (and while in the womb). For example the diet of a baby can affect its intelligence later in life. For example breast feeding a baby will result in more intelligence over not using breast milk. And countless other factors, but diet is the big one, it makes a person.

    3. Re:What else can be found by Mydron · · Score: 1

      Pick up any psychology book and take a gander. The tabla rasa argument which you purport has been proven to be mostly optimistic hot air by countless twin studies. Its true that your environment and the opportunities you've been exposed to play an important role in 'success' especially by our western definition of the word, but you're talking about human traits - something far more primal.

      Sorry, but Einstein wouldn't have been 'retarded' no matter what his physical environment (please spare me the 'repeated head trauma' argument). If your parents are of limited genetic stock its mother nature's genetic plan - and not your hard-luck story of self-pity - that you can blame for not falling far from the tree.

      And finally your last point: If you think genetics raises scary possibilities in China you should consider the thousands of abandoned Chinese girls and the thousands more killed at birth - by and large a result of the one child law. Its all well and good sit here and comfortably banter about genetics but don't confuse bad politics and bad science.

    4. Re:What else can be found by raldanash · · Score: 1

      You're right to point out that multiple genes can affect one phenotype....

      On the other hand, suppose you have 50 genes that affect "intelligence." Stupid scientists only know of 3. If you can affect those 3, that's still a marginal improvement (by the way, the have found portions of chromosomes that correlate strongly with super high IQ kids).

      Also, you probably aren't right about lifestyle being so super important in terms of how athletic you are. A recent study (reported in the NY Times as well) shows that 10% of people will always be physically impressive no matter how much they work out, and 10% will always be buff or toned no matter how sedentary they are. Other results also show that a lot of "athletic traits" are independent, in other words, you're muscular, strong, or have good endurance, but their's no correlation.

      Also, the twin studies that show how similar twins that were raised apart are, and the adoption studies that show a host of tendencies that adoptees have in common with their biological parents (IQ, criminality, etc.) rather than their adoptive parents are disturbing.

      It's not all genetics, but I think you're post indicates you overplay the environmental hand.

      --
      NO gods, NO governments, NO [OPTION]....
    5. Re:What else can be found by PaulGibson · · Score: 1
      Very simply, you can't screen for most human traits.

      Well, this is true in the way that someone in the 1920s saying "We can't fly the speed of sound." was true. Right now we can't. But, with our understanding of the human genome just now beginning to evolve beyond just "It makes us grow", it is quite possible that we will be able to accurately correlate a sequence of set of genes to various attributes. It is also true that many of these would initially be expressed in terms of potential, but would still need the right nurturing environment to bring them out.

      Hopefully we will eventually be able to screen for the "I want something for nothing" gene and disappearing from the consumer landscape will be a boatload of drug companies, the George Forman line of cooking products, and the entire take this pill to (choose one): increase your IQ, ejaculation distance, breast size, cilia length (no more utensils!), ability to sit on your ass and watch TV all day in leu of getting up and contributing to society in some meaningful way industry.

    6. Re:What else can be found by alanwj · · Score: 1

      This raises some scary possibilities, especially in parts of the world where reproduction is controlled by government (China) or families are encouraged to have male children. (Quite a bit of the world, actually.) Having a gender imbalance will do a number on women's rights.

      Humans are odd. Among species that have a large male to female ratio (ants, bees, etc), the females are made queen. Though I agree with your implied assessment that tilting the ratio significantly in favor of males would probably result in oppressed females. Plus, it would make it even harder for a geek to get a date.

      Alan

    7. Re:What else can be found by prizzznecious · · Score: 0

      Who modded this up?

      As others have said, making wide and snotty proclamations about the capabilities of science and assuming that those capabilities will stay constant is a recipe for embarrassment. You would almost have had a point if you had claimed that the development in the womb (protein interaction etc) has more to do with the resulting person than the DNA. In the future, though, look for babies cultured in tubes (or artificial wombs, if tubes make you nervous) rather than gestated in wombs; i.e., we will certain reach a point where we will be able to control every stage of the development process. And if we can do that, we can probably "flash" brains with the upbringing we want them to have. Artificial intelligence will make the creating of these artificial upbringings pretty easy.

      I'm not saying this is a good or bad thing. But you are far too myopic and arrogant for your own good.

      --

      visit the hwky website for a lyrical genius infusion.
    8. Re:What else can be found by cryptochrome · · Score: 2

      Because so many girls in china are aborted, killed at birth, or abandoned, there already is a huge discrepancy in gender there. Which is making things very difficult for men in China. They've taken to seeking wives out of the country quite often. I suppose women have no trouble finding a mate, but it may be that they are excessively coveted and pushed into politicized marriages as a result. I suppose the easiest way for the gov't to take care of the excess male population is to go to war, killing some and letting the rest steal/rape women.

      Boo fucking hoo. They screwed themselves with their gender bias - the one child policy was just a catalyst. The Chinese government routinely screws over their people, but this time it's really the people's fault (won't stop 'em from blaming outsiders as usual though, I bet).

      --

      ---If you can't trust a nerd, who can you trust?

    9. Re:What else can be found by tgibbs · · Score: 1
      Besides the fact that most traits are caused not by one gene, but by the interaction of dozens of genes and the proteins they create, you have to consider that almost all human traits develop in accordance to someone's environment.
      You hear this said a lot, but it really falls more into the category of "wishful thinking" than science. We'd like this to be the case, because it would let us put off the difficult question of where (or if) to draw the line. "We won't be able to do it anytime soon, so we don't have to worry about it."

      The fact is that we don't have the least knowledge how many genes need to be altered to make a significant alteration in a human being. There might well turn out to be a relatively small number of common genes that significantly impair mathematical, musical, social, or athletic ability. Screen out any one of them, and you greatly improve your offspring's chance of excelling in that particular area.

      And once such a gene is found, it automatically becomes a genetic disease. Find a gene that prevents you from having perfect pitch, and you've defined "impaired pitch perception disorder" (IPPD) which musically-inclined parents will imediately want to begin screening for.

      The handwaving about "environment" is similar nonsense. Yes, all traits develop as an interaction between genes and environment, but there are plenty of examples of traits that express themselves in a wide range of environments. Sure, you can probably screw just about any child up by locking him in the basement and never talking to him, but that's more relevant to child abuse than genetic screening.

      Answers? I don't have one. I think we are going to see screening for such traits within a decade. And I don't think it is possible to stop it, because you really can't draw a line that defines the difference between genetic disease and natural variation--there simply isn't one. So if it isn't done here, it will be done somewhere else.

      And there will be undoubtedly be problems and unintended consequences.

    10. Re:What else can be found by Anonymous Coward · · Score: 0

      Hey, the ones that survive are gonna be in pretty high demand once the ratio drops to 80-20 or so...

    11. Re:What else can be found by cappadocius · · Score: 1
      Having a gender imbalance will do a number on women's rights.

      Not to mention dashing the hopes of countless geeks trying to get laid.

      --

      omnia tua castra sunt nobis

    12. Re:What else can be found by ShooterNeo · · Score: 1

      Actually, there is a way. Take an individual who you KNOW has certain traits, and clone em.

    13. Re:What else can be found by Anonymous Coward · · Score: 0

      i don't get it. you don't have to use DNA to "create" a blue eyed blond person, you simply copy and paste the appropriate parts out of a DNA library. how do you find those parts? do the equiv of a "diff" on several tens of thousands of complete DNA samples, and see the difference in visual appearance/characteristics and DNA.

    14. Re:What else can be found by markmoss · · Score: 2

      Say you're an intelligent but pudgy software engineer/couch potato type and you actually manage to get the doctors to screen embryos and sperm most likely to create an athletic individual. If the child created may have a better chance of becoming atheltic, but if he follows his parents example, he will probably be just as pudgy.

      Better idea: select for the genes that allow some couch potatoes to stay reasonably slender and healthy.

    15. Re:What else can be found by JohnPM · · Score: 1

      Besides the fact that most traits are caused not by one gene, but by the interaction of dozens of genes and the proteins they create, you have to consider that almost all human traits develop in accordance to someone's environment.

      This has been the traditional view, that environment and parenting determine the outcome of one's upbringing. However twins' studies have been turning up some amazing evidence to the contrary.

      In some cases of identical twins who were brought up in completely separate households, the twins have met again as adults and discovered incredible similarities in their lives.

      An excellent overview is this Discover Channel site. In particular, check out the Jim twins.

      --
      Karma police, I've given all I can, it's not enough, I've given all I can, but we're still on the payroll.
  11. Screening != GM by Bonker · · Score: 5, Insightful

    All doctors did was select an unaltered embryo that had a better chance of developing into a healthy adult. They didn't change the embryo in any way, nor did they give any advantage to the mother or embryo.

    Some doctors encourage people who are at risk of genetically transmitted diseases to have their unborn fetuses screened for those same diseases so that they have the option of aborting early in the pregnancy.

    This merely takes that practice a step further, while eliminating the controversy of abortion.

    --
    The next Slashdot story will be ready soon, but subscribers can beat the rush and slashdot the links early!
    1. Re:Screening != GM by Drachemorder · · Score: 2, Insightful
      The way I understand it, they didn't select an embryo at all ... only an unfertilized egg, which was then fertilized and implanted.

      To me, that doesn't seem to have many implications (if any) for the abortion debate, since not even the most conservative pro-life advocates argue that unfertilized eggs should be counted as human beings. On the other hand, if they fertilized a number of eggs, selected from the resulting embryos, and destroyed the rest, then there would be a legitimate concern.

      This does raise questions of "playing God", though, along with all the classic arguments about using this to select for or against desired features.

    2. Re:Screening != GM by Spamhead · · Score: 1
      *Flamebait Sensors On!*

      What about the fact that in 10 years this Mom has a %50 chance of not being able to be a parent anymore?

      How selfish is this? "I want a child so much that I will risk the possibility of making it's life miserable in a decade."

      Gee, thanks Mom.

      --
      Everybody Wang-Chung tonight!
    3. Re:Screening != GM by bark76 · · Score: 1

      The article said that there was a chance she could develop alzheimers, not that she had it already. They prescreened the unfertilized eggs for the gene to reduce the likelyhood of her child developing early alzheimers. Why shouldn't she have children if there's a chance she'll never develop the disease? How is not allowing defective people to reproduce any better than GM'd babies?

    4. Re:Screening != GM by mcg1969 · · Score: 1

      This practice does not eliminate the controversy of abortion, only reduces it. Don't forget that a large number of embryos were purposefully destroyed. In the view of many (but not all) pro-life advocates, life begins at fertilization, not implantation---so destroying embryos purposefully is no less wrong.

    5. Re:Screening != GM by maxpublic · · Score: 2, Insightful

      Yes, yes, but we all know that the pro-lifer fanatics are fucking idiots whose primary interest is in enforcing their smug religious beliefs on everyone else. No rational person gives a rats ass what they think on the matter.

      Max

      --
      My god carries a hammer. Your god died nailed to a tree. Any questions?
    6. Re:Screening != GM by freerangegeek · · Score: 1

      It's eugenics to eliminate an embryo based on an single trait. It's not the "grand repair the genome and build a perfect baby genetic manipulation", but taken over time and across a wide segment of the population the effect is the same. Elimination of the gene.

      Should it be legal to select an embryo on the basis of single gene or even a set of genes? Selecting against obvious genetic problems like spina bifida, strong predisposition to Alzheimer's, or Down Syndrome seems to make sense, to me at least. Picking the point on the curve to stop is the 'problem'. What about when the trait doesn't correlate to death, or severe disability? Near sightedness? Asthma? Non homozygous sickle cell anemia?

      Current theory correlates a certain gene on the X chromosome with homosexuality in males. This 'trait' is considered to be very bad by some segment of the population. Should it be legal to screen against an embryo on this basis? Beyond the obvious social engineering problems, there is also the question of what traits are 'bad'?

      AIDS research has led to the discovery that some significant portion (23%?) of Northern Europeans have defects in the protein markers on their CD4 cells. This seems to be correlated with a better chance of survival to bubonic plague. What happens when we eliminate a 'defective' gene that is actually a built in survival mechanism?

      Genetic variability is natures way of protecting us from the unforeseen changes. Do we want to engineer population so genetically uniform that we invite disaster?

    7. Re:Screening != GM by Anonymous Coward · · Score: 0

      Is abortion still a controversy? didnt the dark ages end a long time ago?

    8. Re:Screening != GM by Anonymous Coward · · Score: 0

      All health care is "playing God". Get over it.

    9. Re:Screening != GM by Anonymous Coward · · Score: 0

      The dark ages ended, but people kept on committing murder.

    10. Re:Screening != GM by Derkec · · Score: 2

      True, this isn't going in and screwing with DNA. But this is excactly the process described in Gataca and we should be cautious in its use. In the fairly near future, it is likely to be possible that we will screen for heart problems, the "fat" gene, and other common 'problems'. Next shortness, super-agressive or passiveness and anything else that one could be genetically predisposed to and the parents find less than optimal. We could raise generations of super-babies leading to, of course, the social problems of Gataca. Furthermore, if we have lots of super-babies and say, China does not. Would we be at risk of thinking ourselves so superior as to become very arrogant? We're entering territory where caution is warranted, that's why this is news.

    11. Re:Screening != GM by Dyolf+Knip · · Score: 2
      Nearsightedness runs in my family and I would love to be able to ensure any children I have don't get it.

      I look at it this way. In the absense of government intervention, Designer Children are going to happen. The only real choice they have is whether or not to outlaw it. I doubt half measures like restricting screening for certain genes would be effective. There's so many traits that if we waited for a committee to decide on each one, and you can be sure there'd be a 10,000 page report and 10 year wait on each, we'd never get anywhere. And as you pointed out, it has the problem of 'what is a bad trait'; acceptable screening would blow with the political winds. So, if one is unable to make this decision, look at the alternative: not letting people remove undesirable, even if it means not necessarily bad, traits from their future children. Government dictation of the genomes of the next generation.

      If the alternatives are unacceptable, then the decision is made for you.

      Side note: That's a very interesting tidbit about the bubonic plague resistance; natural selection on humans at work. I'm curious, what are some of the other consequences of this defect?

      --
      Dyolf Knip
    12. Re:Screening != GM by Anonymous Coward · · Score: 0

      Owww, lokie. I got an ouchie! I go get a band-aid. Oh shit, now I playing god! ;-) Hey, let's just sit down and die now. That would be better, hmm yes.

    13. Re:Screening != GM by mph · · Score: 1
      Side note: That's a very interesting tidbit about the bubonic plague resistance; natural selection on humans at work. I'm curious, what are some of the other consequences of this defect?
      The relationship between malaria and sickle cell anemia is also an interesting story along those lines.
  12. Dude by Unknown+Poltroon · · Score: 0, Flamebait

    I can see the corn you had for lunch yesterday.

    --
    All Troll + "offtopic" mods are meta moderated as "Unfair", because you abused the system.
  13. The best application of science ever! by evilpaul13 · · Score: 1, Insightful

    Think of all the famous people who made great contributions to humanity who wouldn't have even been born if we do this nonsense widely in the future!

    Maybe the reason that if there is intelligent life out there among the stars that they haven't found us is because they all genetically engineer themselves into extinction? Afterall, we couldn't leave something important like reproduction up to natural selection and chance, could we? But I'm undoubtedly a just troll for not jumping on the latest biotech bandwagon.

    1. Re:The best application of science ever! by Indras · · Score: 2, Insightful

      Unfortunately, natural selection is no longer capable of weeding out medical weaknesses on a large scale needed to make evolutionary progress. Most diseases are cured, instead of killing the patient, which would remove the defective genes from the gene pool (sorry that sounds so cruel, but it's true). I think this application of science is a very good thing, because it plays with disease prevention. No human being is harmed in the process, and the result is a healthier baby, and improved genetic quality in the species as a whole. Who can argue?

      --
      The speed of time is one second per second.
    2. Re:The best application of science ever! by dragons_flight · · Score: 2

      Think of all the famous people who made great contributions to humanity who wouldn't have even been born if we do this nonsense widely in the future!

      That's not a meaningful argument unless you include reasons why genetically selected or modified offspring won't make at least the same contributions as the people they are displacing. Just because mankind starts selecting against disease or for intellect and atheleticism, doesn't mean that these children would be less capable of making great contributions to humanity. In fact, many advocates of GM would argue that they would be more likely to make great contributions than their randomly created counterparts.

    3. Re:The best application of science ever! by jgerman · · Score: 2

      That's not insightful, that's silly. Think of all the famous people who could have been had we started this screening sooner. This could be an entirely different world, for better or worse, whichever way you look at it. For all you know the contributions of those selected could dwarf the ones of those who had not been.

      --
      I'm the big fish in the big pond bitch.
    4. Re:The best application of science ever! by IdiotBoy · · Score: 1

      Until it is discovered that by eliminating the luekemia gene, we left ourselves open for some Antarean Lemon Fever.

      Which is more resistant to attack, a homogenous network of fully patched OpenBSD boxes or a heterogenous network of multiple operating systems? Today, it may seem that the all OpenBSD network would be most secure.. but what about when the blackhats discover a remote root exploit is found for OpenBSD?

      And we haven't even performed a full source audit on our DNA.

    5. Re:The best application of science ever! by Tadrith · · Score: 1

      No, but you should be. Not for making a statement, but for making generalizations and assumnptions.

    6. Re:The best application of science ever! by jason99si · · Score: 1

      Natural selection will still work fine. The more diseases we cure, the more the bugs become resistant to our cures.

      I think a super bug or two will come along and wipe out large groups of people all at once. Basically instead of natural selection happening gradually, it will start to take a stepped approach.

    7. Re:The best application of science ever! by subsimian · · Score: 1

      Most diseases are NOT cured, rather the 'vectors' that allow a disease into a population are eliminated (managed).

    8. Re:The best application of science ever! by jamezzz · · Score: 2, Insightful

      Who's to say that this isn't just another phase in our evolutionary process? How many of these great contributors have died from diseases that we may be able to screen for in the future? Had they lived on would they have contributed much more? Having lost my grandfather to Alzheimers and having watched the mental pain that he and our family went through, I can't see how this could be unethical or immoral. On the contrary, I could see it as unethical to prevent people from persuing this preventative measure.

      Obviously, there are those who will abuse the technology, since that's true for anything that's great, it's really a mute point.

    9. Re:The best application of science ever! by evilpaul13 · · Score: 2

      My understanding of this process is that multiple eggs are fertilized and then screened and the best is selected. That means multiple human embryos are being discarded. Those are all unique human beings, you know.

      Who are we to say the one discarded wouldn't have been the next Beethoven, and the one kept won't grow up to be a drug dealer? I'd rather see such decisions left to nature and chance.

      Why not focus our genetic engineering efforts on something much less controversial and useful to those imperfect humans already born and find a cure for cancer, aids, etc?

    10. Re:The best application of science ever! by geekoid · · Score: 2

      OR
      Think of all the famous people who will make great contributions to humanity who wouldn't have even been born if we don't use this in the future!

      Maybe the reason that if there is intelligent life out there among the stars that they haven't found us is because they didn't genetically engineer themselves?

      Its a hard issue, what if this allows you to be sure a child won't have the same genetic heart problem his father has.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    11. Re:The best application of science ever! by Anonymous Coward · · Score: 0

      Just once, I'd like to seem some BSD/Linux/UNIX fucknob talk without using a metaphor for a fucking operating system. Can you do me that favor? Because right now, you're about as annyoing heatsink fan ready to die: whiny, ineffective, and a bit on the hot side.

      Even your faggoty unfunny comment is faggoty and unfunny.

    12. Re:The best application of science ever! by pangloss · · Score: 2
      This reminded me of a chain mail that makes its rounds every so often, sometimes as a pro-life argument:
      If you knew a woman who was pregnant, who had 8 kids already, three who were deaf, two who were blind, one mentally retarded, and she had syphilis; would you recommend that she have an abortion?

      If you answered yes, congratulations, you just killed Beethoven!

      Anyway, genetic pre-screening *is* a slippery slope. There wouldn't be such fierce continuing debate if there weren't compelling arguments and thought experiments in favor of screening. I'm not sure how I stand on the issue. My first inclination is to come up with a list of things that can legitimately be screened for. I'm just not sure how you prevent such a list (which I assume would start out with very widely agreed upon horrible hereditary diseases) from eventually including eye color, height, breast size, etc.
    13. Re:The best application of science ever! by egomaniac · · Score: 4, Insightful

      By the same token, who are we to say that your (say) twelve year old daughter's next ovum wonn't contain the best genetic material on the planet?

      You're letter her *not* have sex? How dare you waste such potentially valuable genetic material? The second she gets gives birth to her first baby, make sure her boyfriend starts going for number 2. One of her fifteen kids might be the next Beethoven, after all.

      I realize I'm being inflammatory, but I'm making a serious point. Every menstrual cycle wastes an egg. Every ejaculation wastes billions of sperm. I don't see a whole lot of difference between wasting them a few seconds before conception and wasting them a few seconds later.

      (Yes, yes, I know that some people believe that a single cell can somehow possess an invisible, incorporeal, supernatural entity which they term a 'soul', but that theory is every bit as plausible as saying that the zygote possesses an invisible super-powerful wombat. They might, but considering there's absolutely no evidence in favor of it...)

      And we *are* focusing our efforts on curing AIDs and cancer. Solving these problems does not require every single human on the planet to devote 100% of his or her effort to their solutions. That's a pretty inefficient way to operate. For that matter, what are you doing here on Slashdot? Why aren't you working on something more important?

      The human race multitasks. Nobody complained about Linus Torvalds writing the Linux kernel instead of working on a cure for cancer. Why are you complaining about fertility doctors working on this rather than a cure for cancer?

      I'm sure a lot of people will be pissed off by my opinions, but at least we can all agree on one thing. Super-powerful wombats would be *damned* cool.

      --
      ZFS: because love is never having to say fsck
    14. Re:The best application of science ever! by Indras · · Score: 1

      Why not focus our genetic engineering efforts on something much less controversial and useful to those imperfect humans already born and find a cure for cancer, aids, etc?

      I'm sure these things are being done as well, as we speak. Scientists don't just focus on one topic at a time, you know :o).

      Who are we to say the one discarded wouldn't have been the next Beethoven, and the one kept won't grow up to be a drug dealer? I'd rather see such decisions left to nature and chance.

      Do you really believe that selection for a disease will determine what kind of person you are as you grow up? That the gene that causes early-onset Alzheimer's Disease can make the difference between a Beethoven or a drug dealer? I don't. I think it has a lot more to do with the morals you are raised with, the opportunities you have in front of you, and the desire to reach your goals ingrained into you via your family and friends. I personally suffer from very premature baldness inherent in my father's side of the family, and I'm doing everything possible to make my life more successful. I'm the only one I know (personally) with an Associate's Degree at nineteen years old, and making $22 an hour as a network technician. Also, my fiance's brother is top-notch material. Born and raised for football, joined the Marines, and did great until his friends convinced him to get into drugs... let's just say he won't be out of prison for a while.

      Helping prevent children from getting Alzheimer's Disease will prevent that gene from being passed on in your family. That little added bonus should give them a boost in life. Nothing else really should be affected.

      --
      The speed of time is one second per second.
    15. Re:The best application of science ever! by Indras · · Score: 1

      Most diseases are NOT cured, rather the 'vectors' that allow a disease into a population are eliminated (managed)

      You are very right, on the scale of the entire species. I was referring to a single person. I get sick with strep throat. I go to the doctor. I take antibiotics. Strep throat gone. Had I not treated it, eventually it could have formed into a full-blown infection, causing a very high fever that would have the potential to kill me and ruin my chances for spreading my genetic information.

      Point being: this disease is no longer a part of natural selection because of medical advances. Most diseases are.

      --
      The speed of time is one second per second.
    16. Re:The best application of science ever! by Indras · · Score: 1

      Ack! My first post mistake! Correction: "Most diseases are." = "Most diseases aren't."

      --
      The speed of time is one second per second.
    17. Re:The best application of science ever! by Anonymous Coward · · Score: 0

      (Yes, yes, I know that some people believe that a single cell can somehow possess an invisible, incorporeal, supernatural entity which they term a 'soul', but that theory is every bit as plausible as saying that the zygote possesses an invisible super-powerful wombat. They might, but considering there's absolutely no evidence in favor of it...)

      Hmm. There's no evidence that you have a soul either. Does that make it OK for me to kill you?

    18. Re:The best application of science ever! by egomaniac · · Score: 2

      Hmm. There's no evidence that you have a soul either.

      Quite correct. I do not believe that souls exist, given the complete lack of evidence in their favor. That of course means that I do not believe that I possess one.

      Does that make it OK for me to kill you?

      Most Christians don't believe that animals have souls, either. Do you run around killing people's pet dogs and cats and then claim that it's okay because they don't have souls?

      The Mona Lisa doesn't have a soul. Is it okay to break into the Louvre and torch it with a flamethrower?

      The presence of absence of an invisible, incorporeal, supernatural being hovering around a material body is not what causes murder to be wrong. Murder is "wrong" because it has been defined as such by society.

      The fact that murder's wrongness is defined by society, as opposed to the presence of a soul, is quite clear to an objective observer. Strangling a happily sleeping baby is demonic. Shooting a godless infidel heathen soldier from whatever country we happen to be at war with today can net you a medal and a promotion.

      If you believe that both the enemy soldier and the sleeping baby have souls, your decision of whether it was right to kill them clearly hinges on something other than the presence or absence of a soul. Thus, you clearly do not believe that the presence of a soul is what makes killing wrong, no matter how you rationalize it to yourself internally.

      I don't know why I'm wasting my time responding to an AC troll, but whatever. Still hoping for my super-powerful wombat of doom...

      --
      ZFS: because love is never having to say fsck
    19. Re:The best application of science ever! by Tackhead · · Score: 2
      > And we *are* focusing our efforts on curing AIDs and cancer.

      And while we're at it, AIDS appears to have made a jump from other primate species to us.

      But why to chimps get SIV (Simian Immunodeficiency Virus) and not die from it?

      The same reason a small percentage of the human population can contract (and carry) HIV and yet not die of it, nor even show symptoms.

      In any population, some individuals will be resistant. The other primate species went through this a few million (or even hundred-thousand) years ago, and the resistant primates outbred the non-resistant ones. Voila, a population of chimps that carry SIV, but don't die from it.

      Barring a cure or vaccine for AIDS, the same will happen with homo sapiens. The goal of developing a cure/vaccine is to avoid the economic impact of a disease-induced population crash.

      Side note: There's anecdotal evidence that resistance to smallpox and AIDS is somehow related to what happened during the Black Death. The lack of resistance to smallpox to native North Americans is well-documented. This may be due to their isolation from all the diseases that have traipsed across Europe and Asia and Africa for the past 10000 years.

      Molecular biologists are going to have some fascinating stories to tell, not the least of which is that our present modern culture may owe its existence to accidents of time, geography, and biology.

    20. Re:The best application of science ever! by Anonymous Coward · · Score: 0

      Afterall, we couldn't leave something important like reproduction up to natural selection and chance, could we?


      Until all humans are genetically engineered, we are leaving it up to natural selection and chance. Nature will choose whether the genetically altered children will reproduce more, or less. Meanwhile, when you decide whether or not to genetically alter your children, you take a chance.


      Personally, I'll let my children be fertilized the old fashioned way, thank you.

    21. Re:The best application of science ever! by caferace · · Score: 1
      I realize I'm being inflammatory, but I'm making a serious point. Every menstrual cycle wastes an egg. Every ejaculation wastes billions of sperm.

      Cue Monty Python....

    22. Re:The best application of science ever! by Anonymous Coward · · Score: 0

      Think of all the famous people who made great contributions to humanity who wouldn't have even been born if we do this nonsense widely in the future!

      Think about it. Imagine if Kurt Kobain had been born without musical talent, but also without Bipolar disorder. Imagine if Beethoven had never created a symphony, but was able to hear. Imagine if Edgar Allen Poe had never suffered from psychosis, but also never wrote a poem. Imagine Vincent Van Gogh, unable to paint, but not suffering from schizophrenia.

      In each of these incidences, I would guess that there would be a net detriment to society, but at the same time, I would argue that the individuals would have lived happier lives.

      Of course a parent is going to want to give his/her child the best life possible. And of course the government is going to have the sometimes opposing goal, to benefit society as much as possible. So yeah, we'll probably wind up regulating this procedure away, in the end.

    23. Re:The best application of science ever! by Anonymous Coward · · Score: 0
      You fail to:
      • Use English spelling
      • Use English grammar
      • Make even a smidgen of sense
    24. Re:The best application of science ever! by Dyolf+Knip · · Score: 2
      Think of all the famous people who made great contributions to humanity who wouldn't have even been born if we do this nonsense widely in the future!

      That is about the dumbest argument you can make. Just think of all the famous people who were never born because it happened to be this sperm instead of that one that fertilized the egg. By your reasoning, I am guilty of pushing all my potential fraternal siblings out of existince; shame on me! How about we all have as many kids as we possibly can because if we don't, we'll be dooming potential contributors to humanity to nonexistence.

      --
      Dyolf Knip
    25. Re:The best application of science ever! by evilpaul13 · · Score: 1

      No, it's quite an intelligent one. There have been plenty of people who have genetic defects who have made significant contributions to humanity. They would have never been born if we screened them for defects before their birth.

      Your argument is stupid, because you seem to suggest that by not manipulating nature we're doing something strange and unusual. Nature has done fine on its own for 4 billion years, there's no need to start deciding what people should be born and not born now.

    26. Re:The best application of science ever! by evilpaul13 · · Score: 1

      This isn't about curing defects, it is about selecting which embryo should be born based on a lack of defects. Our time would be better spent on curing diseases than on manipulating nature and deciding we know best who should be born.

      It is a matter of should we let Kurt Kobain be born by chance, or should we select one of his brothers who is in someway superior to him to be born instead?

    27. Re:The best application of science ever! by Dyolf+Knip · · Score: 2
      How many important people haven't been born because someone with a genetic defect was born in their place? The argument works both ways, though it's a pretty safe bet that many of those with defects have enjoyed their lives less than someone without it would have.

      There have been plenty of people who have genetic defects who have made significant contributions to humanity. They would have never been born if we screened them for defects before their birth.

      Oh of course. But what about the other 99% of people who had genetic defects but didn't do anything particularly amazing? Oh, well they have to live with their disability for the sake of that 1%. Gee, how kind of you to demand that of them.

      there's no need to start deciding what people should be born and not born now.

      Really? Funny, my girlfriend and I do that every time we have sex and use birth control. By doing so, we deny the existence of countless children. You are arguing, "Just think of all the famous people who would have been born if nobody ever used a condom." Stupid.

      --
      Dyolf Knip
    28. Re:The best application of science ever! by evilpaul13 · · Score: 1

      Yours is an idiotic biologically deterministic view of human development. 99% of people regardless of an inherent defect of some kind don't do anything amazing. Are they to be deprived of existence too for lacking a "wonder gene"?

      Preventing pregnacy using birth control isn't even related to the topic at hand. Stupid.

      The whole point, which seems well beyond your meager comprehension, is that there are people with genetic defects who have made significant contributions to society. Those people would not have been born if they were screened as embyros and flushed down a toilet. Many people are born with or acquire disabilities and live happy lives, and would rather live with a disability that to have never lived at all.

      Pull your head out of your ass, drop your elitist attitude, and realize that you don't know what is best for everyone else. The only thing that surprises me is that you could find (or pay someone enough) to have sex with you.

    29. Re:The best application of science ever! by Dyolf+Knip · · Score: 2
      Depriving someone of existence?!?! Since when is that a crime?

      Forget historical figures, you're looking at them with 20/20 hindsight; you know what their disability was and you know how they overcame it and you know what they did for the benefit of mankind. Such knowledge is totally unavailable to us for people being born down the road. Such knowledge has no bearing on the problem at hand.

      Now, consider yourself to be a prospective parent. You have undertaken the responsibility of creating a new person and spending the next 20 years raising them to adulthood. At the beginning of this long journey, you are given two embryos. One of them has had blatantly unhealthy genetic problems removed. The other has some unfortunate genetic defects courtesy of your genome. Sure, they might overcome them and do something great, just like any fairly healthy person could. But it might just doom them to a short and miserable existence. Which do you choose?

      I am well aware that people with genetic problems have made contributions, some of them extremely significant. So what? If all you know about your potential children is that you can choose between ones with lots of potential medical problems and ones with fewer of them, why would any parent choose the ones with more?

      Bear in mind that a person who does not exist yet doesn't actually have a say in the matter. Of course people alive today say that they wouldn't trade themselves in, they're here to contest it. If they aren't, they can't, and the decision is left to the parents.

      And I'm going to be very nice and overlook the ad hominem remarks, no matter how inappropriate they may be.

      Lastly, birth control is a perfectly valid analogy. There's this potentially great and important person who will not exist because her parents did not conceive her. With screening it's because they instead conceived someone else. Do we actually prosecute Mom, Dad, and the local geneticist for the nonexistence of this person?

      --
      Dyolf Knip
  14. Bad example to make an example out of by hij · · Score: 2, Insightful
    This doesn't even seem to be borderline. From what it says in the Washington Post article they examined the eggs before being fertilized. Cleared eggs were fertilized later.

    Even St. Thomas Aquinas can't object to this. The discarded eggs were not fertilized. Of course, he might have been upset that he missed out on the fun part...

    --
    Believe nothing -- Buddha
    1. Re:Bad example to make an example out of by Anonymous Coward · · Score: 0

      There is a fun part?

    2. Re:Bad example to make an example out of by Lontas · · Score: 2, Informative

      "Even St. Thomas Aquinas can't object to this. The discarded eggs were not fertilized."

      It should be noted, however, that the eggs were fertilized unnaturally outside of the womb. St. Thomas Aquinas would surely object to that.

    3. Re:Bad example to make an example out of by totopo · · Score: 1

      As much as I like the washington post, it seems that the reporter has mixed up the facts. The abstract/article states that the eggs were fertilized and then the embryos screened. The researches harvested the polar bodies 1 and polar bodies 2 and screened those for the mutation. For those of you who haven't studied mitosis and fertilization, polar body 1 exists before fertilzation but contains two copies of half the chromosomes. Polar body 2 is released after fertilization and contains 1 copy of the remaining chromosomes. By screening the polar bodies, you would need to fertilize it first, as it states in the methods in the full text, which is available freely

  15. Extension of evolution? by ch-chuck · · Score: 2

    Natural evolution (random genetic drift/mutation generation of species and natural selection for survival) works but only up to the point of reproduction - the bad things that happen (like old timers disease) AFTER reproduction don't get weeded out but are passed down from generation to generation of sufferers. Things like this would be helpful to improving the quality of life AFTER childbearing, which is becoming the biggest part of life, in the developed world anyway.

    Of course, anytime humanity plays God, there room for abuse and evil (breeding sex slaves, mercerary warriors, etc).

    --
    try { do() || do_not(); } catch (JediException err) { yoda(err); }
    1. Re:Extension of evolution? by volsung · · Score: 5, Funny
      Of course, anytime humanity plays God, there room for abuse and evil (breeding sex slaves, mercerary warriors, etc).

      It is interesting how two industries that are always well-funded are the porn industry and the military. :)

    2. Re:Extension of evolution? by dragons_flight · · Score: 2

      In communities with active extended families, genetic effects that occur after childbearing do exert an evolutionary pressure (albeit generally a small one).

      For instance, if I was financially responsible for the care of parents who had become senile at the same time I was planning a family, then I would probably want fewer kids to help moderate the financial burdens.

      Conversely if my parents were active, healthy, and available to babysit and otherwise help with caring for my children, then I might be comfortable having a larger family.

      Obviously there are ways around these effects and people may not have active extended families, but I just want to illistrate that in modern interconnected society, genetic influences can have an evolutionary impact even long after childrearing age.

    3. Re:Extension of evolution? by captaincucumber · · Score: 1

      well, you're sort of wrong, healthy parents are favored by evolution because this increases the likelihood of the child surviving.

      But it's a minor point.

      Anyway, I'm in favor of more natural selection in the human race, I think we're really letting it go to pot, if you know what I mean. Seriously, in the US, only the trailer trash have kids (statistically speaking). We're going through a sort of reverse evolution. Since for the human race we're not in a "only the strong survive" evolutionary situtation - in fact, we do everything we can to keep the weak alive and able to reproduce - humans are no longer practicing natural selection at all. It can't be a good thing long term.

      So I think it's great that we're getting closer to Gattaca. Anyway, Gattaca had a great story line, but the future world they described - where people are discriminated against based on genetics - was pretty implausible. And honestly, if that does happen, it's not tied to genetic modification. I mean, we can do genetic modification without living in a world where people are discriminated against on the basis of their genetics - and we can discriminate on the basis of genetics without genetic modification. Even though the movie ties the two together in a paranoid sort of way, they're not connected at all.

      So that's my 2 cents.

    4. Re:Extension of evolution? by Anonymous Coward · · Score: 0

      Actually the evolution magic works even after reproduction. If mother gets alzeimer (as in this case) by the time child is only 10 or so, then child's health and social ability can be impacted. This means that the child has a lesser chance of finding a mate and passing the genes.

    5. Re:Extension of evolution? by GungaDan · · Score: 1
      "two industries that are always well-funded are the porn industry and the military"

      Porn industry well funded? You'd think they could afford a new soundtrack.

      --
      Eloi are stupid, throw morlocks at them!
    6. Re:Extension of evolution? by RetroGeek · · Score: 1

      Don't forget religion. Don't believe me? Go to any small town, and there sits a church.

      Do this in Europe, and it might be a BIG church.

      --

      - - - - - - - - - - -
      I am a programmer. I am paid to produce syntax not grammar. Deal with it.
    7. Re:Extension of evolution? by volsung · · Score: 1

      Well, I guess we've got sex, politics, and religion covered.

    8. Re:Extension of evolution? by Anonymous Coward · · Score: 0

      Porn industry well funded? You'd think they could afford a new soundtrack.

      But then how would we know we were watching porn?

  16. designer babies by I+Want+GNU! · · Score: 1, Redundant

    There are two potential uses of genetic screening before giving birth, in my opinion.

    1) Screen for potentially harmful diseases, such as Alzheimer's, and prevent them.

    2) Test for other traits such as height and eye color, etc.

    #1 is OK in my opinion, since it simply tries to prevent a person from having genetic conditions for their entire lives. #2 would be terrible if used, though, and could just create a bunch of Michael Jordans as babies. It does not save people's lives, it simply makes everyone else worse off in comparison, and is the type of thing used in Gattaca.

    I think that designer babies are ok as far as eliminating disease but could hurt genetic diversity and cause genetic elitism if used to try to get the perfect baby.

    1. Re:designer babies by jgerman · · Score: 2

      I think that designer babies are ok as far as eliminating disease but could hurt genetic diversity and cause genetic elitism if used to try to get the perfect baby.


      Tread softly, you're walking down a dangerous path. If genetic diversity is considered an absolute "good" the next logical step is to be against inter-racial reproduction. It causes the same result, though it decreases genetic elitism.


      That being said, I should point out that genetic diversity is a good thing health wise. It's what stops diseases from running rampant through the whole of humanity.

      --
      I'm the big fish in the big pond bitch.
    2. Re:designer babies by Sandor+at+the+Zoo · · Score: 1
      #1 is OK in my opinion, since it simply tries to prevent a person from having genetic conditions for their entire lives. #2 would be terrible if used, though, and could just create a bunch of Michael Jordans as babies. It does not save people's lives, it simply makes everyone else worse off in comparison, and is the type of thing used in Gattaca.

      Oh, no! This situation was shown as "bad" in a movie! We must stop it from happening in real life!

      Seriously, I have a healthy daughter and another kid on the way. If I could choose their genes such that they were not susceptible to allergies, cancer, bronchitis, obesity, mental disorders, bad teeth, goofy looks, bowleggedness, etc. I'd do it in a second.

      Would I choose a clone of Michael Jordan? Probably not. Would I choose the best genes I can give my children? In a split second.

      Gattaca was a good movie, but I view it not so much as a warning, but as an indicator that the human spirit is not measured in genes (which I'm not so sure of) and that people can triumph over whatever system tries to keep them down.

      Gene selection will happen. It makes just too much sense.

      If the U.S. outlaws it, two things will happen: rich people will go to other countries to pick their kids' genes; the healthcare costs of the U.S. will skyrocket while the costs in other countries nosedive.

    3. RE: Designer babies by Slotty · · Score: 1

      Ok that's just wrong we shoudln't start F'ing around with the human genome next you're going too be able to determine the sex of your child. The only case of genetic manipulation that should be allowed is being able to select the type of bone marrow for it too be compatible with your first child or a parent otherwise NO GENETIC F'ing around At what point do human's have the right to play God when we are flawed and God is not

    4. Re: Designer babies by NerveGas · · Score: 2

      >next you're going too be able to determine the sex of your child.

      You already can. There are now machines that will seperate sperm cells that have either an X or a Y chromosome... because the Y chromosome is so much smaller than the X, the machines are able to shine a light through each individual cell, and with a decent degree of accurateness, decide which it is.

      steve

      --
      Oh, you're not stuck, you're just unable to let go of the onion rings.
    5. Re:designer babies by susano_otter · · Score: 2
      1) Screen for potentially harmful diseases, such as Alzheimer's, and prevent them.

      2) Test for other traits such as height and eye color, etc.

      3) Profit!!!

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    6. Re:designer babies by I+Want+GNU! · · Score: 2
      Oh, no! This situation was shown as "bad" in a movie! We must stop it from happening in real life!
      I've thought about this long before movies like Gattaca came out. That was just a good example of what could potentially happen. If it is allowed, I'm sure it would be expensive, and only the rich countries would be able to afford it and there would be an extreme polarization of the classes. Rich people would get better genes and a new form of extreme aristocracy would be born. Meanwhile, people in the poor countries couldn't afford this.
    7. Re:designer babies by Tackhead · · Score: 2
      > Tread softly, you're walking down a dangerous path. If genetic diversity is considered an absolute "good" the next logical step is to be against inter-racial reproduction. It causes the same result, though it decreases genetic elitism.

      I don't follow your logic here -- if genetic diversity is an absolute "good", banning same-race reproduction would be the more logical alternative.

      (Actually, neither alternative would maximize genetic diversity -- the alternative that maximizes genetic diversity would be to ordain that all mating pairs must be selected at random. This would seem to be a contra-evolutionary strategy, however, as the point of selection - both natural selection and artificial selection - is that the more-fit genes propagate, and the less-fit genes don't.)

      Given that human tastes in fashion and culture change on a 20-50 year timeframe, I'd say designer babies aren't a problem.

      Just a few hundred years ago, we'd have been selecting for "fat chicks", because of that Reuben guy (where do you think the word "Reubenesque" comes from?) and the notion that being fat meant you had enough food to eat (and were therefore a "good catch"). In the 70s and 80s, we'd have sprogged a generation of anorexics with big hair. 30 years from now, fat will probably be "in" again. (rejoice, potatoes of the couches!). Maybe people will get fed up with having to wash and style their hair and a "baldness" fad will set in.

      If we allow culture and fashion to dictate which genes reproduce... oh, wait a minute, that's what we're doing at the high schools, the dorms, the workplaces, the nightclubs. Designer babies will merely accelerate the process.

      It could even be a Good Thing. Consider that with all the experimenting, evolution might find something interesting and worthwhile in all the mistakes that'll be made. (Some parent who thinks synesthesia is fun, and who asks for it by design because there's a correlation between synesthetes and great artists...)

    8. Re:designer babies by Christopher+Chang · · Score: 1

      > Tread softly, you're walking down a dangerous
      > path. If genetic diversity is considered an
      > absolute "good" the next logical step is to be
      > against inter-racial reproduction. It causes
      > the same result, though it decreases genetic
      > elitism.

      On the contrary, interracial reproduction vastly increases genetic diversity, as long as it is sufficiently randomized. The best result (from a diversity standpoint) is something resembling a continuum.

      That said, it is worth noting that increased interracial reproduction accelerates natural selection (by providing more variance, that critical raw material for selection to operate on), and one consequence of this is that "obsolete" genes could decrease in frequency more quickly. But frankly, I think all the real downsides will be mitigated far before they could possibly be relevant.

      The notion of designer babies is a potential major threat to diversity, however. If they become sufficiently widespread, genetic diversity will needed to be consciously managed on a global (well, hopefully multi-global, but sadly I don't see large-scale colonization of other bodies in the solar system occurring before widespread designer babies) level. Hopefully this can be done with a few minimally intrusive/disruptive policies.

    9. Re:designer babies by Anonymous Coward · · Score: 0

      #2 would be terrible if used, though, and could just create a bunch of Michael Jordans as babies.


      Yeah, sure, everyone's going to screen to produce a tall, black, basketball playing, male.

    10. Re:designer babies by jgerman · · Score: 2

      Not true. Not that I'm against interacial reproduction in any way shape or form, but it's fairly simple to see: Different races are prone to different diseases, for exampl sickle cell anemia. Over an extended period of time race becaomes less and less of an issue as more and more interacial children are born. Take this to a point in the far future where there is technically only one race. A single disease, or virus, can run rampant through the entire world population because the potential for catching it has been bred into the entire population. It doesn't even have to be an existing disease, say a new type of AIDS appears in 3000 years that by some trick of nature attacks only people of a certain race, or would have if the genes of different races weren't mixed to a point where there is only one race.

      --
      I'm the big fish in the big pond bitch.
    11. Re:designer babies by Anonymous Coward · · Score: 0

      equals "rich get richer, poor get poorer."

    12. Re:designer babies by Anonymous Coward · · Score: 0


      Ahhhh. But your examples fall into two easy categories. What about obesity? It increases the risk of heart disease. But many parents might want to eliminate it for aestetic reasons. This is only one example of "gray" areas.

  17. Natural Selection? by Em+Emalb · · Score: 5, Insightful

    From the article:
    "Without the screening, the newborn would have faced fifty-fifty odds of becoming hopelessly senile by the time she was 40."

    This is a terrible thing. I am really sorry to hear that this *might* happen by the time she/he is 40.

    Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

    What happens when the governments start screening every child that is born for any inherent form of "weakness"? Will those children never receive the chance to live? Will they be branded "inferior"? This has the potential to be an extremely bad thing.

    If you want a child so badly, lady, go ADOPT ONE.

    There are literally thousands of unwanted children out there that need and want a family.

    What is so wrong about going this route as opposed to paying thousands for a procedure like this? You help a child already alive, and more importantly, you give that child a chance to have a better life, and that is what it's all about.

    of course, this is my opinion, and I am sure I will be slammed most heartily....

    *cracks open a beer and waits*

    --
    Sent from your iPad.
    1. Re:Natural Selection? by gUmbi · · Score: 2

      Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

      Doesn't any form of medicine or medical treatment disrupt natural selection? We aren't in the jungle anymore - live with it.

      Jason.

    2. Re:Natural Selection? by juggler314 · · Score: 1

      I think there is nothing wrong with screening or genetic modification for wanted traits. While it is true that this kind of leaves darwin out of the survival of the fitest race the simple fact is that darwinism doesn't drive human evolution anymore. Humans are way too good at altering their environment to have natural selection play a role in expressing genes. As far as another comment on "Gattaca" while there could be some discrimination in the future I believe that would only be a transitory time just like for anything else. Once science gets good enough at it EVERYONE will be smart and healthy. Will this be such a bad thing? I don't think so it's not as if we will all be clones, there will still be "more genius" amongst all the "normal genius":) People will still have areas of specialty and it may well be shown that creativity can't be programmed leaving plenty of room for valuable traits that you can't pre-plan. If that's the case everyone being strong/smart/etc wont be that great if they all long to be able to paint but can't.

    3. Re:Natural Selection? by Xzzy · · Score: 4, Interesting

      > Weaknesses are inherent in all forms of life. And
      > in this case, the weakness is basically being
      > forced out of the child. I don't think this is a
      > good thing, and here is why...

      How fair is that to the child? Is it not the parent's responsibility to give their offspring every positive chance in life they can get? The short of it is, there are innumerable diseases and afflictions that plague humanity that are passed through the genes. Most of them have no cures to date, and considering the money put into research these days, it's hard to remain optimistic that cures will ever be found.

      What's so evil about weeding out these undesireable genes? It SUCKS to have to live with a hereditery disease, just try on my shoes sometimes because I gotta do it every damn day.

      If my parents had had this opportunity, I would have encouraged them to take it. Because if I had never been born, I wouldn't be around to care if I didn't exist. I have no illusions about my importance to this world to try and claim that if I didn't exist, the world would be a worse place. And even if I weren't here typing this, some other child of my parents would be out there doing something, sans disease. Sounds win-win to me, because the kid I could have been was raised by the same two people and would probably end up with the same core values.

      > If you want a child so badly, lady, go ADOPT ONE.

      Course, I'll agree with you on this one. I don't see myself ever having a kid, cuz I don't wanna pass on my shit-for-genes to any descendents. If I ever get that parental urge, I'll probably adopt. Adoption, for as long as there are orphaned children, is the better solution. But that doesn't make "gene screening" evil by any means.

    4. Re:Natural Selection? by Anonymous Coward · · Score: 0

      You obviously have no (legitimate) children, so maybe it's time you quit posting to slashdot and go back to your full time pursuit of rubbing it out whilst wasted.

    5. Re:Natural Selection? by xSterbenx · · Score: 4, Insightful
      Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

      I can't disagree more. The point of natural selection is that some organisms are more prone to survival than others, and for the most part this increase in survival is due to a genetic mutation which somehow made the organism more 'fit' to survive. By screening for 'unfit' genes, we are actually performing natural selection ourselves, instead of relying on random chance mutations which more often than not lead to 'unfit' phenotypes.

      Besides, when was the last time natural selection was really evident in humans? We take care of our sick, our unhealthy, those of us who cannot survive on their own. According to natural selection, we should not give charity, should not have nursing homes, should not really do anything that does not benefit ourselves. IMO, applying natural selection to humans is wrong in any case.

    6. Re:Natural Selection? by Indras · · Score: 2, Insightful

      Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child

      Two problems with these statements. First of all, all medical technology, safety equipment, processed foods, medical procedures, etc. (ad nauseum) goes against natural selection. In the human race, natural selection doesn't exist anymore. Also, Alzheimer's Disease isn't usually something that can be filtered out via natural selection, because it usually begins affecting a person long after (s)he has passed on their genetic information to the children.

      Second, nobody's forcing weaknesses out of anyone in this experiment. They are preventing a child from being born with a disease, not creating a bunch of children and killing off those with the disease, or creating one child and modifying their DNA after they're born (virtually impossible, since it must be changed in every single cell) to remove the gene.

      I don't see anything wrong with this morally.

      --
      The speed of time is one second per second.
    7. Re:Natural Selection? by Anonymous Coward · · Score: 0

      I won't slam your opinion (you're entitled to it) but I'll give a some info and counter-points.

      First, there may be thousands of unwanted children, but there also seem to be thousands of parents that can't have kids and want to adopt. So why aren't these two groups hooking up? Probably because the parents are being selective with their adoption. It's their right to be selective, plain and simple. My point: there's more to the equation. You can't just tell people to adopt kid-X for the same reason you can't restrict the use of KDE. You also can't force a woman to be an incubator and not abort. Not trying to go off track here, just saying that people will want to choose how they setup their lives.

      As to natural selection and government involvement, I think you're taking that part way too far. There's nothing wrong with ensuring a healthy child. If it gets into choosing certain qualities, yeah it's a bit Dr. Frankenstein-like, but it isn't evil by any means. There's no super-baby that can make a well-accepted desktop under Linux waiting in the shadows, trust me.

      I'm mostly middle-of-the-road with my politics, with a slight slant to the Republican side. Still, I'm totally against the anti-abortion/control-freak mentality. (trust me I'm getting to my point) Parents are pretty much on their own. You'll get a right-winger who says "Abortion is murder! You can't abort!". Problem: they don't want to take care of the child they supposedly saved. There are services to help children/people with minor and major disabilities, but that doesn't make the hardship any easier. Just think how horrid it would be for two people to produce a being who has to suffer through life. These people will shoulder that burden for the rest of their days (unless the child dies early). You won't see any pro-lifer running to their side.

      Okay, so it's really weird. I'd rather have weird than unnecessary suffering. Again, I think you have good points....but I think there are more variables than you're willing to consider.

    8. Re:Natural Selection? by WinPimp2K · · Score: 3, Insightful

      As someone pointed out earlier, this has no impact on "natural selection" as the disease being screened for doesn't show up till long after the woman was capable of having offspring.
      Natural selection would mean each of her children would have a 50 percent chance of carrying the gene AND passing it on to their kids as well.

      As was also pointed out, this happens BEFORE the eggs are fertilized. Unassisted (the old fashioned way) reproduction would not lend itself to this approach and would certainly leave no point of entry for your government intervention. If governments decide to get into the "species improvement" game, they don't need such a medically expensive method. Just consider the German eugenics programs of the 1930s, or the PRCs more recent "healthy birth" laws which may or may not be a eugenics program favoring the ethnic Hans.It certainly is an attempt by a government to eliminate babies with undesireable traits.

      As to the adoption argument, well people are funny that way. Most people would rather have their "own" children - its that little bit of immortality they get through their kids. And so many would rather spend the money (if they have it - or good insurance). If you personally find yourself in the position that this woman was in, you and your partner may make your own decision regarding reproductive options. But please stop trying to limit the choices available to others.

      --

      You either believe in rational thought or you don't
    9. Re:Natural Selection? by gehrehmee · · Score: 4, Insightful
      Weaknesses are inherent in all forms of life.
      Furthermore... weaknesses are one of the things that define us. If I was more physically adept, for example, I would have certainly been more likely to have focused on that element of my life as a child. Instead, I found that I, socially, was very different from the people around me. That forced me to seek out and use my other strengths, and make them a more important part of who I am. I sought out different peer groups, different friends. My family's different because I'm different...

      I think when you really consider it, our weaknesses are as much a contributing factor in who we are and who we will be as our strengths. And I believe any attempt to fiddle with that is going to be detrimental, both to individuals, and to the society they go on to live in.
      --
      "You know, Hobbes, some days even my lucky rocketship underpants don't help" -- Calvin
    10. Re:Natural Selection? by rlowe69 · · Score: 4, Interesting

      Well, IMO, this goes against natural selection.

      I have no problem with your opinion except this point. The reason being that by improving medicines and such, we are ALREADY going against natural selection. To put it bluntly, and it's hard not to make this sound completely immoral, we are weakening the human race as we speak. Let me take a chance to explain.

      Let's take the simple example of sight. If I'm completely near-sighted I can get a pair of glasses. In the days when natural selection mattered for humans and sight, let's say 500 years ago, I might die before I can have offspring because of my poor sight. THAT is natural selection. My genes are now removed from the gene pool before I can "replicate" them into others - and because of natural selection, fewer and fewer people have poor sight.

      Now let's take this to another level. Let's say a recessive gene that causes a disease is common among a population. If that population surives past sexual maturity and passes the gene along, natural selection fails and the disease's gene spreads. This is a decidedly bad thing.

      I won't even get into the moral grounds of the issue, I just wanted to give another side of the coin. It's not necessarily my two cents - but probably someone's ... and definitely something to consider when you bring up natural selection.

      I too, expect to be flamed. :)

      --
      ----- rL
    11. Re:Natural Selection? by jgerman · · Score: 2, Insightful
      Yes I do have to slam you for this, because it makes no sense.


      Number one, don't start blabbering about natural selection. That wen't the way of the dinosaur years ago. The world today does everything it can to keep weakness in the gene pool. Diseases are treated so that they thrive, rather than being allowed to be filtered out. Diabetes for example. Civilization can be defined as the force that attempts to get past natural selection (on an individual basis at least) by keeping the weak alive. I'm not saying this is good or bad it's just the way it is.


      Secondly, adoption is another way that society keeps potentially harmful genes in the pool. Orphaned children most likely come from parents who, for some reason or another, could not function in society, and the chances that these children will not be able to function as well.


      Keep in mind I'm not expressing a stance on the subject here, only that the further civilization progresses, the more it grows away from natural selection.

      --
      I'm the big fish in the big pond bitch.
    12. Re:Natural Selection? by 8string · · Score: 1

      While I agree with your conclusion that genetic engineering == bad, some of your logic is flawed.....

      >Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

      So does anything associated with modern medicine. I would have died from a ruptured appendix when I was 10 had it not been for (modern) surgery and medication.

      >What happens when the governments start screening every child that is born for any inherent form of "weakness"? Will those children never receive the chance to live? Will they be branded "inferior"? This has the potential to be an extremely bad thing.

      This has already happened. Most people think of Nazi Germany, but it's happened here too. Read up on Eugenics and the forced sterilization of those labeled (correctly or otherwise) by govt doctors as mentally retarded.

      >If you want a child so badly, lady, go ADOPT ONE.

      I agree completely. But, the problem is that it runs against the grain of our consumer culture. Can you really expect a woman to adopt a rejected (implied inferiority) child rather than pay for her own superior (through genetic engineering) child, when the same woman would rather get liposuction than commit to working out in the gym for 6 months?

    13. Re:Natural Selection? by SirSlud · · Score: 2

      > Humans are way too good at altering their environment to have natural selection play a role in expressing genes

      Says who? Gene selection may ultimately see the shucking of gene's responsible for our desire to control our enviornment.

      Also, our species is young, and our 'control' experiment is *extremely, extremely* young.

      > Once science gets good enough at it EVERYONE will be smart and healthy

      Except that while we may wish to blend in, we are also driven by a need to stand out. If everyone's 'smart', we simply offload our judgements of whats 'smart' or 'good' onto other things we have no control over. (Maybe back to racism? Oh, then we can ask our kids to have a non-hate-inviting skin tone.)

      All control we execise is an illusion. We solve problems, more crop up as a result. That's the human experience, although our economy relies so heavily on ignoring that simple fact that we can't possibly conceed to it until we experience the next major shift in cultural and social values and beliefs.

      --
      "Old man yells at systemd"
    14. Re:Natural Selection? by 8string · · Score: 1

      What's so evil about weeding out these undesireable genes?

      Or, in another context:

      Hitler (speaking to Himmler):What's so evil about weeding out these undesireable genes?

    15. Re:Natural Selection? by jdavidb · · Score: 2

      You have good points, but I have some criticisms.

      What happens when the governments start screening every child that is born for any inherent form of "weakness"?

      It is a long jump from "I had my offspring screened," to "the U.S. gov't now screens all children (which requires a constitutional amendment, I'm sure)." Just because the first situation happened doesn't mean the second is right around the corner. I'm sure we all agree the second is wrong, but that doesn't mean the first one is.

      If you want a child so badly, lady, go ADOPT ONE.

      That's easy for you and me to say. But we're not in her situation.

    16. Re:Natural Selection? by Spencerian · · Score: 1

      Rocky slope, this. Or, is it?

      We know that heredity-based traits and illnesses cannot be corrected as a whole. Some of them include:

      Cystic fibrosis
      Hemoglobin-C trait
      Sickle-Cell trait

      When it comes to illnesses that a vaccine cannot remove, I'm all for egg-sorting. Sure, this is a form of manual selection, but it gives that person's line a chance at extension--which is what life's all about. It wasn't as if none of the woman's eggs were free of the preemie Alsheimers and the doctors modified an egg. The woman's body did the job of making a better human-potentiate: science simply helped to identify it. Her body was the cure. Nature scores again, with an assist.

      For this stuff, this technique should be great. But tayloring otherwise viable eggs without hereditary, life-diminishing issues--BUZZZ! That's a bad idea not just ethically, but also in God-playing. We can remove or add something that stops or starts a vital element--say, a protein that helps with a critical function. In that case--leave stuff alone.

      --
      Vos teneo officium eram periculosus ut vos recipero is.
    17. Re:Natural Selection? by Em+Emalb · · Score: 2

      You are absolutely right in your assessment that everyone is entitled to be selective in choosing a child for adoption, aborting a child, etc. I don't disagree with this at all. I think any legislation that doesn't allow free will is not a good thing.

      One more thing, you are 100% correct in your thinking that these people screaming for other people to adopt aren't exactly following through in their advice/stances. Bet you 90% of them would change their toon if they saw some of the conditions these children are growing up in.

      Now, back to my original point, if you know a child will be born with a chance to get alzheimers, then why would you risk it? So, you can change the chance of her/him getting this tragic disease. What about the other diseases out there? Don't care about them? Why stop there? I have blues eyes, but I want my child to have brown? That is what I mean. I would be willing to bet, although I will most likely be dead by the time it happens, that this child STILL gets some other form of disease. Mom Nature don't like being cheated :)

      thanks for the thoughtful response...now if we could just teach the rest to not slam someone's opinion but counter it, then the world would be a better place.

      --
      Sent from your iPad.
    18. Re:Natural Selection? by neo · · Score: 2

      "Well, IMO, this goes against natural selection. "T

      his is natural selection, in fact it accelerates it. The other eggs effectively "died", while the chosen egg survived. That's natural selection jumping a generation or two.

    19. Re:Natural Selection? by austad · · Score: 2
      Well, IMO, this goes against natural selection


      natural selection
      n.
      The process in nature by which, according to Darwin's theory of evolution, only the organisms best adapted to their environment tend to survive and transmit their genetic characteristics in increasing numbers to succeeding generations while those less adapted tend to be eliminated.


      Ok, so tell me exactly how this goes against natural selection. We are humans, we are evolving, and we are doing it by learning things about our environment and putting it to use.

      About the only thing that would go against natural selection is if you found a genie in a lamp and wished away all of the bad genes that cause disease. However, these diseases are part of our environment, and we've discovered how to overcome them ourselves.

      --
      Need Free Juniper/NetScreen Support? JuniperForum
    20. Re:Natural Selection? by Anonymous Coward · · Score: 0

      good god I wish I had mod points for your post.

      +10 insightful, but only cause I agree with it...gotta slam everything I disagree with you know :)

    21. Re:Natural Selection? by CodeMonkey555 · · Score: 1
      While I totally agree with you on the adoption issue and peoples' irrational desire for their *own* child, I think you are wrong about the natual selection side of this. Keep in mind that this defect wouldn't affect the child until it was 30-40 at which point, according to nature and our original life spans of less than 40 years, the person would no longer be adding their genes to the pool.

      Just my crazy ideas...

    22. Re:Natural Selection? by Brown · · Score: 1

      Well, IMO, this goes against natural selection.

      Yup. This is most definately against natural selection. This is engineered selection. Rather than waiting for 'nature' to randomly kill off bad genes, we can now kill them off immediately - and noone has to get killed to do so.

      In my opinion, this makes natural selection redundant; we can do it better. (with due care and research of course, but that's another question altogether). TBH, natural selection, while simple and effective in the long term, never was real pretty for those actually in the grinder, as-it-were; what's wrong with fixing it when we have the capibility?

      This is of curse what our civilisation has always been; a way to cheat at natural selection!

    23. Re:Natural Selection? by bitrott · · Score: 1

      How do you know your peer groups didn't influence the way you percieved your physical adeptness? At a young enough age children can develop muscle mass very quickly and speed and stamina is rarely a problem. You may have been more predisposed to "hang out" with the friends you did, not because you weren't the Jock type, but because a certain song, parent, other adult influenced you enough to seek differenct kinds of companionship. Don't try and simplify life. It's really much more complex than all that.

    24. Re:Natural Selection? by geekoid · · Score: 2


      Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

      You misunderstand natural selection.
      1. its survival of the fitest. In the case fitest means the ones most adaptable to a change in there enviroment. I would argue that the screening IS a change in the enviroment and those that use it are the most adaptable, or fitest.

      2. It is for a disease that has a 50% chance of striking at age 40, this means they,in all likeleyhood, will already have children, and thus past on the gene. With screening you'velowered then chance of this diseas, not only for your child, but all there children as well. Thats means the HUMAN races will have a higher likelyhod of survivng.

      Could there be problems with this? sure but you're arguements against it are false.

      Finaly, have you ever gone through the adoption process?

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    25. Re:Natural Selection? by Anonymous Coward · · Score: 0

      I'm surprised it took so long for some simpleton to whip out the tired Hitler analogy. Shouldn't you be at a Focus on the Family convention somewhere? That was propaganda, and apparently you bought the liberal, warm milk version of things.

    26. Re:Natural Selection? by Drachemorder · · Score: 1

      "Can you really expect a woman to adopt a rejected (implied inferiority) child" Yes. My mother did exactly that, for which I am profoundly thankful.

    27. Re:Natural Selection? by bitrott · · Score: 2, Insightful

      Indeed? A dog crapping in a forest is no more natural than a chemical plant, or a geneticists lab. We are all in and of nature. There's percievable order for sure, but how do you know this possiblility isn't the order of tomorrow? To what ends? It's the journey there that's keeping luddites awake at night. It's the ends that keep me in a coffee shop all hours of the night debating crap philosophy with my peers and equals.

    28. Re:Natural Selection? by Anonymous Coward · · Score: 0

      This actually right inline with evolution. Evolution has taken the species so far the next step is to improve our selves.

    29. Re:Natural Selection? by Steveftoth · · Score: 1

      It brings to mind the thought that if we don't build robots to replace outselves, then we may end up turning ourselves into organic machines of another type. If everyone is genetically engineered, controlled down to the last chromosome, then what's the difference between that person and a machine? A soul?
      Does a perfectly engineered being still have a soul?
      What about clones, would a clone have a soul?

    30. Re:Natural Selection? by DahGhostfacedFiddlah · · Score: 1

      Nothing's wrong with weeding out undesirable genes. The problems in your example were
      a) The "desirable" qualities were skewed. This may be true today - whose to say that the Alzheimer (sp?) gene doesn't switch on other, "desirable" genes?
      b) Of course - the method. Killing grown humans is a far cry from discarding eggs that were never going to be fertilized anyway.

      Your argument is little more than saying "Hitler said improving the road system was a good thing - and look at where it got him". Just because it was a thought of an evil man doesn't make it an evil thought.

    31. Re:Natural Selection? by gehrehmee · · Score: 2

      Well, of course it's complex... chaotic in fact. But that's the point. Any little thing that we go actively manipulating has the potential to come back and bite us, (or help us). More importantly, it's virtually impossible to predict what kind of effects we're going to create.

      As for my case personally... I was actually never really healthy has a child... asthma... odd diet... Osgood-Schlatter's Disease (a condition causing inflammation and pain in the knee, especially while exercising) for a while. My physical failings were definately out of my hands. More then that though, I still consider getting glasses in grade 4 to be one of the biggest milestones in my life. It changed the way other children perceived me, fairly or not. Learning at that age that people are, by their nature, occasionally fickle and superficial had an immediate impact on my outlook on getting along with others. A few (not entirely enjoyable) years later and I was able to approach social situations without a serious fear of what kind of repercussions my actions would have on the rest of my life. I could take risks, and ended up with some very strong friendships that I still value today. Looking back, I can honestly say that I'm very glad my parents & the time's technology never made contact lenses or laser eye surgery an option, let alone genetic solutions.

      --
      "You know, Hobbes, some days even my lucky rocketship underpants don't help" -- Calvin
    32. Re:Natural Selection? by Richard_Davies · · Score: 1

      First
      > IMO, this goes against natural selection
      Then
      > If you want a child so badly, lady, go ADOPT ONE

      The "goal" of evolution (of which natural selection is but one part) from the perpective of an individual is to pass on the individual's genes (Read some Richard Dawkins such as "The Selfish Gene" for a more complete discussion). A female can already affect the charateristics in her child to some degree already - by selecting a mate. From a purely genetic point of view, it is completely sensible for an individual to "pre-select" those genes that have the best chance of survival. Adoption guarantees that 0% of the individuals genes are passed on. From a genetic point of view, the lady has made a sensible choice by increasing the chances that her offspring will live to an age where he/she will be able to reproduce.

    33. Re:Natural Selection? by raldanash · · Score: 2, Insightful

      Well, IMO, this goes against natural selection. Weaknesses are inherent in all forms of life. And in this case, the weakness is basically being forced out of the child. I don't think this is a good thing, and here is why...

      A good point. We are changing the germ line in ways we might not know. And we all have deleterious genes. Here is mine in full disclosure:

      Hypercholesterolemia

      Because hypercholesterolemia is dominant 50% of my children will have it (statistically). My family doesn't have a history of heart disease (the side I inherit from, which is my mother's side people tend to get heart disease ... in their 90s since they often make it 100 like my grandfather and my 115 year old great-great-aunt)-so I don't know how bad hypercholesterolemia is for us. My cholesterol is 380, so is my mother's and my sister's. My two brothers and obviously my father don't have it.

      But when I have children, I plan to make sure they don't have it by screening or selectively aborting. But I also wonder-if I don't have a history of heart disease, why??? I don't know. Do we know all the ramifications of hypercholerolemia aside from the heart-disease related ones? Cholesterol is a hormone that affects several processes...including brain development.

      Nonetheless, it is a choice individual parents will have to make. Society shouldn't have to pay for it-you pay out of your own pocket. But change isn't always bad. Throughout most of human history people have been on the verge of malnutrition. Now that's not the case, and the obesity "epidemic" is spreading into the Third World. I'd rather take an obesity epidemic than malnutrition.

      Also, remember that not all humans will take advantage (or will be able to do to money) of the new services, so we'll have a reserver of "untouched" human genes in that population. Taking into account that throughout most of human history there were fewer than 1 million of us, I wouldn't worry about genetic uniformity.

      Fear of the unknown shouldn't hold us back. We should move forward, with caution, but move nonetheless. There is a chance we might fall of the cliff's edge, but the fact is the only other choice would be to attempt to hold still indefinately, and impossible task.

      By the way, would we make a big fuss if the women has simply recieved an egg donor???

      --
      NO gods, NO governments, NO [OPTION]....
    34. Re:Natural Selection? by Zanth_ · · Score: 1

      Regardless of slams against you, I agree for what it is worth to you...

      Cheers!

    35. Re:Natural Selection? by 8string · · Score: 1

      So,

      What's the weather like in Stepford today?

    36. Re:Natural Selection? by PD · · Score: 1

      A person is a machine. And I'm not sure what you're going on about this soul thing. Do you still believe in the monster under the bed?

    37. Re:Natural Selection? by Telastyn · · Score: 2

      Why?

      I mean honestly. Why would you focus on physical aspects of your childhood? There's no reason that's preferred over geeklike activities except societial pressures. And the world has always known of rebels to societial pressures...

      People will be different, even perfect clones are different as they live, even in the womb. They will have individual weaknesses, different problems to overcome....

      This should just make sure they have a better shot not to be eliminated by something they cannot control, such as debilitating genetic illness (ungenetic illness will still strike, as will stupidity)

    38. Re:Natural Selection? by mjh · · Score: 2
      Is it not the parent's responsibility to give their offspring every positive chance in life they can get?

      No, actually, it's not. I am a parent, and I would argue that it's my responsibility to let my children screw up as much as possible. Why? Because we as humans tend to learn through our mistakes, not our successes. By encouraging my childrens opportunities to make mistakes, they learn that daddy is not going to be around to fix their problems, so perhaps they'd better start thinking about how to fix the problems that they create for themselves.

      Of course, there are limits to this. I'm not going to encourage my children to learn the consequences of playing in the street. So I won't encourage mistakes that risk damage to life and limb. But every other mistake that my child is about to walk into, I want as much as possible to stop myself from jumping in and rescuing them. That way they get an oppurtunity to recognize when they're walking into problems.

      (The above is grossly over simplified, but it captures the essence. For more details see Parenting with Love and Logic)

      The short of it is, there are innumerable diseases and afflictions that plague humanity that are passed through the genes. Most of them have no cures to date, and considering the money put into research these days, it's hard to remain optimistic that cures will ever be found.

      The problem with this assumption is that you don't know what other things you're screening out when you screen out the disease. A somewhat contrived example of this is Stephen Hawking. Of course no really knows the cause of ALS, but suppose it turns out to be genetic. Stephen Hawking would have been screened out of existance, and consequently all of his contributions to science.

      IMHO, by doing this kind of thing, we pretend that we are God and that we can forsee every possible future. In my opinion, this is foolishness. We are too focused on our inconveniences, and spend too much effort in the avoidance of struggle. We almost universally fail to see the good that can come out of those struggles.

      --
      Key to financial independence: Spend less than you earn. Save and invest the difference. Do it for a long time.
    39. Re:Natural Selection? by delcielo · · Score: 2

      How fair is that to the child?

      I guess that depends on which child. The child that would have been born naturally, or the child you hand-picked. Admittedly, things get kind of dicey here; but if you pick the genetically favorable one (favorable in your opinion, that is) over the others, how fair are you being to the one or more of the others that would have been chosen naturally? They are not the same child.

      --
      Hot Damn! It's the Soggy Bottom Boys!
    40. Re:Natural Selection? by bitrott · · Score: 1

      So, it was good enough for you, it should be good enough for millions more. Medicine and science are about advancement. You've lived better than any generation before. So well that DESPITE your genetic 'disabilities' you were aided in survival. It's possible that much would be unlikely given the nature of some ancient cultures. Our predecessors will have the chance to live lives that strech eons, free of diseases of the body AND the mind. All it takes is some hard work now.... and the guts to take some chancy risks.

    41. Re:Natural Selection? by YAH00 · · Score: 1

      Ok... let's see...

      Natural Selection. Hmmm.... thats a law chance has forced us into. Why are we limited to following these laws? We won't know until we experiment. Sure you might say that we might end up destroying humanity in experimenting. But isn't that better than not expermenting? Would you rather still be in the dark ages? In the iron age? In the stone age? Stating that natural selection is the only form of evolution is silly. We've already got genetically engineered crops, chicken, cows, pigs. We are the better for this.

      Ok now to weaknesses.... Sure there is a point to your argument that genetically engineerd selection may result in a new class heirarchy ala Gataca. But then there are social and political issues no matter what changes you do. We have to deal with them and figure out a way to properly integrate them into our lives.

      Look at it from the parent's perspective. As a parent don't you want to provide your child with the best possible future? Dosen't a parent select the best school a child can go to. The right kind of food. The right kind of doctor. The right kind of daiper. The right kind of friends. The right kind of environment?

      Why should all this only start arter the baby is born? Why not provide the best even before birth? Why is screening weak genes any more morally unacceptable than screening for a school which has a good reputation?

      cheers

    42. Re:Natural Selection? by Anonymous Coward · · Score: 0

      Dude... you criticize this lady for going "against natural selction", and then tell her to adopt a baby? Make up your fucking mind. You do know what apes in the wild do when they find someone else's infant, yes? Natural selection, indeed.

    43. Re:Natural Selection? by tgibbs · · Score: 1

      Sure it goes against natural selection. So do antibiotics. So what? Natural selection may have supplanted God as an explanation for the origin of species, but that does not make it holy.

    44. Re:Natural Selection? by ShinGouki · · Score: 1

      has it not occurred to you that perhaps the intelligence in the human mind that has led us to be able to screen for this stuff is part of natural selection? what most people don't realize about natural selection is that it's not really that selective (pardon the pun) when it comes to what traits are used for the selection process. EVERYTHING is part of natural selection.

      smart mammals who learn to screen out bad traits have healthier children who go on to procreate and that sort of thing.

      --
      -dk
      Dream with the feathers of angels stuffed beneath your head.
    45. Re:Natural Selection? by Steveftoth · · Score: 2

      I disagree, the human body is a machine, but a person is not a machine. Your body is not all that you are made of, there is more to a person then their physical charactistics.
      I just looked up machine @ dictionary.com just to see what they think is a machine, and they state that a human body (or other complex organic bodies) is a machine. But unlike traditional 'machines' people have many inputs and an undefined output. You can use the word when describing an aspect of people, but then you ignore many aspects of their character.

    46. Re:Natural Selection? by Christopher+Chang · · Score: 1

      > So I won't encourage mistakes that risk damage
      > to life and limb. But every other mistake that
      > my child is about to walk into, I want as much
      > as possible to stop myself from jumping in and
      > rescuing them. That way they get an
      > oppurtunity to recognize when they're walking
      > into problems.

      ...to life and LIMB.

      You just killed your own argument.

      Why aren't you willing to risk your children's limbs? Because that's permanent damage that will stick with them for their entire life that they almost certainly won't be able to do anything about in the future. Unlike the other setbacks of childhood, which are temporary.

      In both cases, the child can learn from the setback, but in the former case they generally lose more than they gain.

      Well, guess what. Genetic screening, for the most part, ONLY deals with permanent issues. Some of which are more crippling than limb damage.

      So, if you're not inclined to risk your child's limbs, you have something to gain from genetic screening.

    47. Re:Natural Selection? by rickbrodie · · Score: 1

      What natural selection? With the development of intelligence, man has found ways around it. Modern medicine among other things have basically caused natural selection to cease, and nobody has said how "immoral" and "irresponsible" this is. The inherent flaws and diseases which, in the animal kingdom, would have led to death before an animal could pass on it's genes have been rendered powerless. People actually think of it as everyone's right to be allowed to reproduce - despite such "natural flaws" as infertility; And ways around this have been duly invented: IVF etc. There are many people who are well aware of their "inferior" genes which could potentially pass on such genetic diseases as haemophilia etc. Yet they shamelessly gamble on odds often no better than 50:50 to have children, regardless. If this precedent were to become common practice, then natural selection might once again start applying to humans again. I believe that this is just another stage in the (un)natural evolution of humans.

    48. Re:Natural Selection? by Manoj · · Score: 1
      Well, IMO, this goes against natural selection.

      Hmm. I have Diabetes. I am myopic. By natural selection alone, I would be dead. I use glasses (in violation of the fitness rule) to improve my sight. I use (gasp) drugs to fight natural selection and live.

      Everytime you go to a doctor and take medicine, arguably that militates against natural selection.

      Unfortunately, we have gotten rid of a lot of diseases and phisical handicaps as selection criteria - but others, often overlooked, have come into play. Selection does not necesarily require the adult organism to die, merely not reproducing, or reproducing less fecundly than other seegments of the population or species, can drive selection too. Just check out the figures corelating birth rates and poverty, or birth rates and education to see what is being selected for modern homo sapiens

      : If you want a child so badly, lady, go ADOPT ONE.

      I think either you have a poor idea of the biological imperative that drives us, or you are delibrately ignoring it for the sake or argument. A desire to have ones genes (or genes close to ones own) to propogate in the gene pool is built in, and far stronger than you give credit for.

      What is so wrong about going this route as opposed to paying thousands for a procedure like this? You help a child already alive, and more importantly, you give that child a chance to have a better life, and that is what it's all about.

      Atruism is not a survival trait. That is not to say it is not laudable, however, basic human nature, one of the very things that allows us to survive as a species, is enlightened self interest. So I don't think giving a organism carrying none of my genes a better life is what it is all about (but feel free to continue to believe that, all the better for my offspring).

      Before y'all jump on me with a flame thrower, I do agre that slefishness needs be moderated with concern for the needs of the herd as well -- humans are not solitary animals, we would have far lower standards of living without division of labour and cooperation. (Also, people may argue that if society did not provide medicine, hospitals and shelter for folks like me who are quite obviously unfit to survive on our own (I would make a lousy hunter gatherer), we could use the resources to better use for folks deemed better investment in the future). Adopting children and caring for the less fortunate in society strengthens it (again, better chances for my offspring/genes to survive). But It is not the only thing that matters.

      I guess I should pull on the absestos underwear now

      --
      Manoj Srivastava Key C7261095 fingerprint = CB D9 F4 12 68 07 E4 05 CC 2D 27 12 1D F5 E8 6E
    49. Re:Natural Selection? by PD · · Score: 1

      What do you mean that my body is not all that I am made of? Bodies are composed of atoms and molecules. We can write chemical formulae for everything that composes a human. This is a no-brainer.

      The actions of a human are the result of a very complex machine. Way more complex than anything we can build out of silicon or plastic, but a machine nevertheless.

      Are you implying that what a person is, does, and thinks is not completely supported by the physical body and brain?

    50. Re:Natural Selection? by Steveftoth · · Score: 2

      yup. At least until you can predict what a person can do next, just like a machine. I'm saying that unlike machines, humans are unpredictable. Until you prove that people are predictable then I'll say that people are not machines. Are you saying that everything you think is the result of a predictable electro-chemical (or whatever else makes up us) process? That you and I and everyone else does what we do without real choice, that we are bound in the clutches of the machine that is the universe, without hope of escaping the destiny that was created for us before anyone was ever born?

    51. Re:Natural Selection? by gedanken · · Score: 1

      In the US in every state, every child who is born in a hospital is required by law to be screened for some particular genetic abnormalities. How many abnormalities that are tested is dependent on where you live and are around 5+ for every state.

      Its strange how many people don't realize that this sort of thing has been going on for quite some time.

    52. Re:Natural Selection? by Peyna · · Score: 2

      What I can't figure out is that either people didn't have bad sight until fairly recently, or it must not have mattered too much! =]

      --
      What?
    53. Re:Natural Selection? by NearlyHeadless · · Score: 2
      The problem with this assumption is that you don't know what other things you're screening out when you screen out the disease. A somewhat contrived example of this is Stephen Hawking. Of course no really knows the cause of ALS, but suppose it turns out to be genetic. Stephen Hawking would have been screened out of existance, and consequently all of his contributions to science.

      Hawking believes strongly in genetic engineering.

    54. Re:Natural Selection? by lkaos · · Score: 1

      Well, no flaming from me atleast :)

      I wouldn't go as far as to say that natural selection is not taking place, but rather that many traits have become vestigual almost overnight (from an evolutionary standpoint).

      Humans evolved to lose their hair. This is because it simply wasn't necessary any more once they figured out how to use animal skins to keep warm. The appendix is another good example of modern evolution. Since humans for the most part do not ingest toxins frequently (due to the cooking process), we simply don't need it so it's disappearing.

      So what good traits are being encouraged by evolution? I think that's tough to say, but I think it's pretty evident that we are becoming smarter as a species (which is rather well documented). While on a micro-socialogical level this may not seem too logically (since stupid people tend to breed prolifically), on a macro-socialogical level it makes sense. Stupid people tend to have higher mortality rates so it would appear that while birth rates may be higher amoungst stupid people, success rate is far greater upon intellegent people.

      Many people try to seperate humans from nature, but we are a part of nature. There isn't anything we can do that isn't natural. Besides, even if we cause a mass-extinction, it's not as if life hasn't been able to flurish (the greatest extinction was something like 96% precent during the pre-cambrian IIRC).

      Now I bet I get flamed :)

      --
      int func(int a);
      func((b += 3, b));
    55. Re:Natural Selection? by DahGhostfacedFiddlah · · Score: 1

      Going off-topic here, but...

      On abortion - I'm not going to give my opinion - I've never been fully happy with either side of the issue, and here's why. I've never seen a pro-choice argument that makes me fully happy with abortion. Piece by piece, here it is :

      **Women have rights over their own bodies**
      --Is the fetus part of their bodies, or are they separate entities?--
      **A fetus is part of a woman's body**

      So - at what point does it stop being part of a woman's body? When it's brain starts functioning? It's heart starts beating? It "looks like" a baby? Or when it's fully out of the woman? Can you "abort" a child while it's still attached by the imbilicle (sp?) cord?

      I know there's no answers - any answers I've received are people's own personal thoughts, not backed up by much reasoning. It's really a religious question at that point. My own personal thoughts are that a fetus become's human sometime in the second trimester. Babies have been born and lived at 5 months. If I had the law in my hands, I'd err on the side of caution and allow only first trimester abortions for this point.

      **They'd suffer their entire lives**
      This is a superfluous point after considering the first. If they're human, you have no right to dictate whether they have to live that life or not. Could a mother legally kill her 3-year-old child if she was sure he/she would suffer most of their life?

      I'm not saying anti-abortionists have better arguments. As I said, it all comes down to "Is this murder?", and the answer is a religious one that I've yet to see a logical solution to.

      Sorry for the tangent thread, but it's been bugging me for a while.

    56. Re:Natural Selection? by zmooc · · Score: 2
      Weaknesses are inherent in all forms of life.

      Don't you think there's a major difference between weakness and illness? You aren't going to die because of your so-called weaknesses (there are probably lots of people jealous of your mental capacities, so maybe your weakness isn't really a weakness at all?) while this child had a fairly chance of dying so I think the comparison between your "problems" and the potential problems this child would have been facing cannot be compared. Although with the technique used here, one may choose to a certain extent e.g. the colour of the hair of your child, but that's NOT what happened here so it would be rather stupid to consider this case "bad" because it uses a technique that can be used to seriously disturb "natural selection". When people start choosing not to have black-haired babies or so using this technique, your complaint would be valid.

      Furthermore, since the eggs and the sperm were taken from the "natural" parents, their genes will remain in the baby so the baby is rather "normal"; it's genes were constructed in a totally natural way, it's just that the selection of the egg happened in a bit of an unconventional way. Speaking of natural selection; in most developed countries there's hardly any natural selection left; anyone can and does have babies which would not have been born if medical science wouldn't have interfered (I'm not saying they shouldn't). So science has influenced natural selection in a major way already (in the "wrong" direction). So then what's wrong about using science to push this back a bit in the "right" direction when we can do so in a very humane way?

      Anyway... the kind of selection you describe in your post is probably not possible since the genes are selected from the gene-set of the parents so the choices are rather limited and natural diversity is not really harmed. I think when we start to construct babies DNA from scratch or something, we're pushing things a bit too far, but as long as it's just a "technique to choose the right egg" I don't really see a problem. I think in this situation it's not the ethical aspects that should worry us, but the rather unknown long-term effects of the hormone-treatment (which is said to increase the chance of cancer for the mother) and the tests on the DNA of the child.

      Please tell me if I'm wrong; it's not like I know anything about all this and made this all up:)

      --
      0x or or snor perron?!
    57. Re:Natural Selection? by bnavarro · · Score: 1

      If I was more physically adept, for example, I would have certainly been more likely to have focused on that element of my life as a child...That forced me to seek out and use my other strengths, and make them a more important part of who I am.

      So I guess that means that under different genetic circumstances, you would be trying to score a First Down today instead of a First Post :)

    58. Re:Natural Selection? by Anonymous Coward · · Score: 0

      The actions of a human are the result of a very complex machine.


      You clearly have never taken a class in quantum mechanics.

    59. Re:Natural Selection? by cappadocius · · Score: 1
      Well, IMO, this goes against natural selection

      natural selection isn't just genetic. The mere fact that we Homo Sapiens exist is proof that fit also applies to social orders and technological skills.

      As much as the green folks may deny it, we are a force of nature too, along with any other part of an ecosystem. The way we decide who lives and who dies/is never born is still a part of natural selection.

      This doesn't make what we do right, but it also doesn't make it 'unnatural'.

      --

      omnia tua castra sunt nobis

    60. Re:Natural Selection? by jonbrewer · · Score: 2

      I quote "this goes against natural selection"

      And I answer:

      I think this sounds to me quite like natural selection. Here we have one couple with the knowledge (she is a geneticist) and the resources (obviously they have money/insurance/both) to produce a baby who won't lose her mind by age 40.

      This type of genetic screening doesn't seem to be any less against natural selection than picking the right food and shelter (requires knowledge) and working/paying for it. (requires resources).

      And their actions certainly don't preclude that same couple from being extremely moral, or even donating a significant portion of their time/earnings to helping other people. (Your unwanted children.)

      When I'm ready for a family in a few years I'm certainly going to have my sperm/eggs/embryo screened for Tay-Sachs, provlivity for heart disease or hypertension, and whatever else I can at the time.

      I wouldn't feel right about bringing a child into the world without doing so.

      And, of course, at that time I'll ask those like you: What *is* natural selection, and where *is* the moral high ground?

      GW

    61. Re:Natural Selection? by rlowe69 · · Score: 2

      Stupid people tend to have higher mortality rates so it would appear that while birth rates may be higher amoungst stupid people, success rate is far greater upon intellegent people.

      While people may disagree with your tone here (and flame accordingly :) ) I'm disagreeing with the statement a bit. As long as "stupid people" survive past sexual maturity and have children, it doesn't matter when they die. In fact, you could argue that uneducated people tend to have children earlier in life (like in their teens) and therefore spread their genes FASTER.

      But I digress. I'm not denying that humans are not bound by nature. However, humans are playing on a more level playing field where natural selection seems to matter less than factors that we have no control over. Smart people can get run over by a careless driver just as easily as a "stupid person" can win the lottery.

      Here's to good luck! *clink* :)

      --
      ----- rL
    62. Re:Natural Selection? by Stonehand · · Score: 1

      Have you considered looking at certain cases of abortion as justifiable homicide? If the life of the mother may be in danger otherwise, and that would suggest self-defense; if the pregnancy was the result of rape, then perhaps it's justifiable as an involuntary burden.

      Anything else, *shrug* I'd think it'd get pushed down to the state level via the tenth, but the justices in Roe v. Wade obviously thought otherwise.

      --
      Only the dead have seen the end of war.
    63. Re:Natural Selection? by DahGhostfacedFiddlah · · Score: 1

      Have you considered looking at certain cases of abortion as justifiable homicide?

      Hmm...no, I hadn't. I think the self-defense idea has some merit, but pregnancy as a result of rape wouldn't matter if you consider the fetus to be seperate from the mother. I can't think of an analogy, but "involuntary burden" seems like a bit of a stretch for justifiable homicide. You could try to claim the same for a mother whose husband has left her - he's in the wrong, but she's got the "burden" of the kids.

      I'd say there are a few cases where it's almost perfectly black and white - most people agree that if there's 100% chance the mother will die, abortion should be an option.

      As for pushing to the state level, then you'd get a system where people are crossing the state line just for abortions. And especially if you want to consider it a case of homicide, it should be a federal solution. Mind you, I don't think that there *is* a good legal solution - there are just too many conflicting ideas. I'm just trying to get out the word about how useless heated discussions on the issue are.

    64. Re:Natural Selection? by mjh · · Score: 2
      So, if you're not inclined to risk your child's limbs, you have something to gain from genetic screening.

      While I am inclined not to risk my child's limbs, I'd rather risk my children's limbs than risk their lives. Your logic seems to suggest that in order to prevent my child from the penalties of a broken arm, I ought to just relieve them of their lives. That may be something that works for you, but not for me.

      --
      Key to financial independence: Spend less than you earn. Save and invest the difference. Do it for a long time.
    65. Re:Natural Selection? by Anonymous Coward · · Score: 0

      They just were bad shots.

    66. Re:Natural Selection? by Anonymous Coward · · Score: 0

      As long as "stupid people" survive past sexual maturity and have children, it doesn't matter when they die.

      Probably, but it's actually much more complicated than that. Not only do those "stupid people" have more children, they die faster and are not around to teach their children safe sex, so their children actually procreate even more (as opposed to what would happen in a society without say a welfare system to take care of those children).

      On the other hand, evolution is not occurring over such small timeframes. The number of people with a particular gene may be increasing or decreasing, but as long as the genes themselves exist, and are not extinct, you can't really say evolution has occurred. When the population starts to approach a point where there is not enough food, shelter, or water to go around, then there's going to be some massive "natural selection" taking place. And likely the ones to survive will be those with the most social intelligence, i.e. the ones who control the nukes (or whatever mass destruction devices we happen to have at that time). Unless there is some global nuclear (or possibly biological) war, I don't expect to see evolution during my lifetime.

    67. Re:Natural Selection? by Anonymous Coward · · Score: 0

      You clearly do not understand quantum mechanics, even if you took a class in it.

    68. Re:Natural Selection? by Anonymous Coward · · Score: 0

      I tried to read what you wrote but your spelling was so atrocious that I gave up.

    69. Re:Natural Selection? by Anonymous Coward · · Score: 0

      Christ, would you at least TRY to spell words correctly?

    70. Re:Natural Selection? by Thing+1 · · Score: 1
      If you want a child so badly, lady, go ADOPT ONE.

      Sounds like you have control issues.

      How is someone else's decision on how to have or not have children any of your freakin' business?

      If you want to adopt a child, feel free. We won't stop you. But don't think you can make parenting decisions for someone else. You can't, and hopefully you never will. (China's a different story.)

      --
      I feel fantastic, and I'm still alive.
    71. Re:Natural Selection? by the+phantom · · Score: 2
      Humans evolved to lose their hair. This is because it simply wasn't necessary any more once they figured out how to use animal skins to keep warm. The appendix is another good example of modern evolution. Since humans for the most part do not ingest toxins frequently (due to the cooking process), we simply don't need it so it's disappearing.


      AKH!! NO! WRONG!!

      I'm sorry, that was terribly rude. But I am going to leave it, because what you say is simply not factually correct.

      First off, natural selection does not work by picking good traits and strengthening them, or by eliminating unecessary traits. There is only one directive to natural selection: those that breed pass on traits. Hair was lost not because it was unecessary, but because less hair humans bred more. This might be due to hairy people dying of heat exhaustion, or simply women finding less hair more attractive. Who knows.

      Secondly, the appendix may be disappearing (I honestly don't know... it is impossible to measure the size of the appendix on a timescale that means anything in terms of evolution), but if it is, it is only because the appendix is an unfit selective trait. I can see how this is possible, as people who die of appendicitus cannot reproduce after they die. However, I see the appendix as a neutral trait, and it is likely to remain for a very long time.

      So what good traits are being encouraged by evolution? I think that's tough to say, but I think it's pretty evident that we are becoming smarter as a species (which is rather well documented). While on a micro-socialogical level this may not seem too logically (since stupid people tend to breed prolifically), on a macro-socialogical level it makes sense. Stupid people tend to have higher mortality rates so it would appear that while birth rates may be higher amoungst stupid people, success rate is far greater upon intellegent people.


      I would like to postulate that the human species is "getting smarter" not because of natural seclection, but because of one adaptive trait. Yes, one trait is all that is allowing people to "get smarter." What is that trait you ask?

      CULTURE

      Culture is the ability to learn behavior, rather then rely on instinct alone.
      Culture allows us adapt to our environment, and adapt our environment to ourselves.
      Culture is the trait that allowed humans to become just about he most ubiquitos species on the entire planet.

      And remember, natural selection does not select for positive traits, but against negative traits (in a particulare niche -- see the discussion on SCA
    72. Re:Natural Selection? by PD · · Score: 2

      Machines can be unpredicatable too. We have machines that generate random numbers (not pseudo random, but REAL random).

      Sorry, you lose. You base your whole argument on the notion that people are unpredictable, but machines are predictable. A random number generator based on a quantum principle like radioactive decay is just as unpredictable as a human, and therefore indistinguishable by your criteria.

      The second minor point is about the "escaping the destiny" concept you brought up. Anyone who has heard of and understands quantum mechanics will recognize the argument as flawed. The randomness in the universe precludes a destiny being created for anyone. The idea that the universe works like a clockwork, with all future states being calculable from the initial state hasn't been believed for about 100 years.

      I'm not saying that you are wrong. I am saying that your argument is COMPLETELY unpersuasive.

    73. Re:Natural Selection? by PD · · Score: 2

      I know more about it than you, obviously! Do you suppose that a quantum computer (when it is built) will not be considered as a machine?

    74. Re:Natural Selection? by markmoss · · Score: 2

      Actually, in the old ways (19th century and earlier), natural selection would have operated against this gene because sometimes the children would die of neglect when the mother's mind degenerated too far to take care of them...

    75. Re:Natural Selection? by WinPimp2K · · Score: 1

      Hmm... the early onset Alzheimers hits in the late 30s/early 40s. The kids could die of neglect if they were too young to care for themselves and had no other adult parent/ older siblings, both conditions are possible but not highly probable. People back then had children earlier. It is highly unlikely that Mom or Dad would have waited till their mid to late thirties to start their families - it just wouldn't be natural :).

      --

      You either believe in rational thought or you don't
    76. Re:Natural Selection? by I.+M.+Bur · · Score: 1

      I know this may offend many of you here, but what do you think about this: every baby, born with some genetic fault should be sterilized. That way it can live its life, become the next Mozart, or Einstein or whatever... Win-win, as I see it.

    77. Re:Natural Selection? by jdavidb · · Score: 2

      No, I didn't! Wow!

      On the other hand, they're not going to order me to kill my child if the genetic code isn't good enough, are they? I'm seeing a future in the catacombs, here.

    78. Re:Natural Selection? by markmoss · · Score: 2

      Correction, I didn't think this all the way through. As someone pointed out, women in that era were usually married by 18. By the time early Alzheimer's begins in the late 30's, their first children would be nearly grown up, and certainly be able to take care of the younger ones. Of course, trying to watch a flock of younger ones plus a demented mother is a hell of a burden for a teenager, and some would fail, but there isn't much of a selection effect here.

      However,men usually didn't get married until the late 20's (they had to establish themselves economically first), and if the father went senile when the oldest kid was 12, the family was in serious trouble. Death directly by starvation was a remote possibility because neighbors, church, and charities would help, but this help generally didn't extend as far as bringing the family out of poverty or bringing the diet up to par with intact and successful families. The kids would be malnourished a bit, and more susceptible to disease. The boys would take risky jobs at too young an age just to get out of there; if that didn't kill or cripple them, they would still have to work a lot longer and harder to reach the point where they could afford to marry, and a good many would remain bachelors. The girls might make an even worse career choice, and prostitutes rarely have babies that survive.

    79. Re:Natural Selection? by Steveftoth · · Score: 2

      Just because you don't believe in something doesn't mean that it isn't true though.

      Whoever said that I was trying to win? Maybe I'm just talking for the sake of talking. But if you want to win, then go right ahead.

    80. Re:Natural Selection? by lkaos · · Score: 2

      While people may disagree with your tone here (and flame accordingly :) ) I'm disagreeing with the statement a bit. As long as "stupid people" survive past sexual maturity and have children, it doesn't matter when they die. In fact, you could argue that uneducated people tend to have children earlier in life (like in their teens) and therefore spread their genes FASTER.

      Once you hit the cap, you gotta burn the karma a bit or it just isn't fun anymore :)

      Using stupid was only because it is easier to type than what I really meant. By "stupid", I am referring to individuals with a lower aptitude for learning. Now, in practice, this can translate to either book learning or street smarts depending on how you want to look at it. It's not only what we traditionally consider as "educated" people succeeding, but any individual who has a greater aptitude for learning whatever it is that they learn.

      I believe this can be traced to the fact that man's success is directly linked to our ability to figure things out. The strongest tribes didn't necessarly win. The tribes that either have the most cunning military or the tribes with the best agricultural skills are the ones that prospered.

      --
      int func(int a);
      func((b += 3, b));
    81. Re:Natural Selection? by PD · · Score: 1

      That's it? That's all you can muster? There's an obvious counter to your statement that's left as an excercise for the reader. (Hint: it's a logical NOT of your statement)

      Go back to school and learn some mathematics and physics. Think deeply about the subject. Then come back to me.

    82. Re:Natural Selection? by Anguirel · · Score: 1
      The previous comments pretty well cover the issue, but I had a few other ideas to share on this...

      Is it not the parent's responsibility to give their offspring every positive chance in life they can get?
      No, actually, it's not. I am a parent, and I would argue that it's my responsibility to let my children screw up as much as possible. Why? Because we as humans tend to learn through our mistakes, not our successes. By encouraging my childrens opportunities to make mistakes, they learn that daddy is not going to be around to fix their problems, so perhaps they'd better start thinking about how to fix the problems that they create for themselves.
      Allowing your children to screw up is fine. Forcing your children to screw up is not. Give them the best chance you can to succeed. If the job is to type a text file on the computer, give them a functional keyboard and computer to type on, not a Typewriter with no ink and 3 keys missing. If they screw up when they've had a chance in the first place, fine... if they screw up because you refused to give them the proper equipment (and you had the chance to do so), that's bad parenting. In the words of the original poster, give them a positive *chance* at success, not a slim margin of comfortable survival.

      The problem with this assumption is that you don't know what other things you're screening out when you screen out the disease. A somewhat contrived example of this is Stephen Hawking. Of course no really knows the cause of ALS, but suppose it turns out to be genetic. Stephen Hawking would have been screened out of existance, and consequently all of his contributions to science.
      If Hawking's genius appears elsewhere in his genetic code than the screened out gene (plus the environmental factors which would have been nearly identical, I believe, since his condition didn't appear until around age 20 or so and wasn't diagnosed until shortly after his 21st birthday) he might have made all his contributions without having to suffer from ALS, thus likely granting him an extended lifespan (since according to the statistics he should be dead already...) in which to make contributions.
      --
      ~Anguirel (lit. Living Star-Iron)
      QA: The art of telling someone that their baby is ugly without getting punched.
    83. Re:Natural Selection? by Anonymous Coward · · Score: 0

      So if you had the ability to choose between giving birth to a child with a brittle-bone condition and giving birth to one without such a condition you would leave it to chance?

      It's not a question of relieving anyone of their lives. It's clear you're not understanding the situation. What kind of sadist chooses to have a child burdened by genetic deformity?

      Can such a child have a happy life? Of course. Would they be happier without such a burden? Of course.

    84. Re:Natural Selection? by Anguirel · · Score: 1

      Poor sight is naturally corrected by a fair margin by the brain. I didn't realize how bad my sight was until I got glasses... and then took them off 20 minutes later. My optic nerves had been compensating for the deficiences of my eyes. The glasses lead to fewer headaches... and poorer uncorrected eyesight.

      Additionally, once society forms, good sight is no longer a required trait. A smith hardly needs the ability to see out a sparrow on a tree a mile distant, whereas a hunter in a desert might need to be able to see a snake in a crack in some rocks a mile distant... All about what's necessary for survival in the current environment. Genetics-wise, we stopped following natural selection when we started having larger-than-a-tribe societies and started to care for the sick.

      --
      ~Anguirel (lit. Living Star-Iron)
      QA: The art of telling someone that their baby is ugly without getting punched.
  18. Re:This is not great news by Anonymous Coward · · Score: 0

    I have a form of autism called Asperger's syndrome. I prefer having the skills/ abilities associated with the condition rather than be *normal*. If this form of genetic selection were allowed to continue for other types of conditions it would lead to a far less diverse society. People with Asperger's are often called geeks, nerds, eccentric etc - but are resposible for a lot of inventions purely because they decided to think differently. Anyway I agree with selection for physical illnesses but not for mental ones. Lots of famous people in history managed perfectly well even with what would be considered today a mental illness. Einstein had Asperger's syndrome, Winston Churchill was manic depressive.

  19. Evolution vs Breeding Out Intelligence by allanc · · Score: 5, Interesting

    Okay, two immediate thoughts come to mind with relation to this.

    First off, with the way that human mating works nowadays, there really isn't much evolutionary motivation. You date people who you find attractive for whatever damn fool reason you have rather than for the purpose of creating healthy offspring. I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive. That's not an evolutionarily sound move on my part, but that's not going to make me dump my lovely girlfriend. So this development makes it possible for Humans to actually take control of evolution and start breeding out diseases and infirmaties.

    However, the problem that immediately comes to mind is something that dog breeders have found over the years. People started breeding for certain traits such as soft coat, ears that are floppy in exactly the right way, short tails, etc. While this makes for very pretty dogs, it leads to the problem that the average Dalmation, far from rescuing its brethren from Cruella DeVille, could just barely rescue itself from a small, wet paper sack. And that's only if it had 100 other dogs helping it. And the wet paper sack also had food in it that they wanted to get to. And maybe was perforated. Which is why sheepdog owners are, last I heard (which was, admittedly, years ago), fighting tooth and nail to keep their breed out of competition. They raise sheepdogs to be /smart/ and /strong/ and /useful/. Not pretty.

    The point I'm trying to make is that genetically manipulating which kids we have to screen for diseases is fine by me, but I'd hate to live in a future where people start screening their reproductive cells so that they only have pretty babies. They'll probably be able to play games with Dalmations on the same intellectual level.

    --AC

    1. Re:Evolution vs Breeding Out Intelligence by Mr.Phil · · Score: 1

      The Old English Sheepdog was approved into the AKC in February 1990.

      http://www.akc.org/breeds/recbreeds/olengshe.cfm

      I do agree with your eval of the Dalmation. One of the, if not the, dumbest dogs around.

    2. Re:Evolution vs Breeding Out Intelligence by raldanash · · Score: 1

      The problem with your analogy is that people breed dogs for one feature. Kids aren't treated like dogs, parents have more of an investment than winning a dog show. From what I know about breeding, a lot of the extreme domestic breeds, of whatever species, are created via intense inbreeding. You take one animal that has what you want, and breed it constantly, and than rebreed the offspring that have the desired trait together until you have only that trait. With this sort of genetic screening, you manipulating or selecting from your own genes and picking the less deleterious one.

      By the way, the future will be filled with more beautiful people-plastic surgery is getting cheaper and cheaper, and when robots get to doing it, will be like getting braces for middle-class kids today. You might as well give your kids a head-start and pay for it upfront by getting it genetically

      Also, please note that "unattractiveness" is often the byproduct of some "bad" gene, so if you get rid of deleterious genes people might naturally become more attractive. For instance, a fetus with a better immune system and hormonol control ends up more symmetrical than it would be otherwise. If you don't think things can happen on the fetal level-did you ever know "identical" twins where one was definately more attractive than the other???

      --
      NO gods, NO governments, NO [OPTION]....
    3. Re:Evolution vs Breeding Out Intelligence by jred · · Score: 1

      I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive.

      I like that, it's probably one of the funniest things I've heard in a long time.

      --

      jred
      I'm not a mechanic but I play one in my garage...
    4. Re:Evolution vs Breeding Out Intelligence by jred · · Score: 1

      That reminds me of something I read recently. The biggest question of the paper (maybe online), was whether or not intelligence was a positive survival trait.

      IIRC, their position was that it is not a positive trait, although I don't remember why nor do I agree..

      --

      jred
      I'm not a mechanic but I play one in my garage...
    5. Re:Evolution vs Breeding Out Intelligence by bitrott · · Score: 1

      Uh. Alzheimer's doesn't make for pretty babies. Alzheimer's makes for cripples. We screen for pretty babies when we pick out hotties in the bar (be they m or f). At this rate though, the genus Nerdus Biggus will be extinct soon enough.

    6. Re:Evolution vs Breeding Out Intelligence by Telastyn · · Score: 1

      Not all Dalmatians. My family has had 2 pure bred Dalmatians, and they most definately could fight their way out of pretty much everything. They were also two very smart dogs. The first learned how to open doors with knobs. (by placing his front feet on the top of the knob, and then falling to the right side, either pushing or pulling as needed.)

      He then proceeded to teach the other one.

      They also quickly grew a little deaf (one of the reasons they are "fire engine" dogs. The other is that they cannot howl.). The only possible genetic problems I've noticed in the dogs was a propensity for arthritis early (10-11 yrs old).

      True though, they were never show dogs, and only the one ever had parentage who were show dogs.

    7. Re:Evolution vs Breeding Out Intelligence by WillWare · · Score: 2
      there really isn't much evolutionary motivation. You date people who you find attractive for whatever damn fool reason you have rather than for the purpose of creating healthy offspring. I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive. That's not an evolutionarily sound move on my part

      Evolution has NEVER required conscious participation by the organism. Evolution does not need your help, nor does it require you to practice any sort of discipline. Intelligence is NOT the goal of evolution. The goal of evolution (speaking metaphorically, see Dawkins) is to maximize fitness, primarily defined in terms of differential reproduction.

      Dog-breeding, while relatively new, is done in a state of two-fold ignorance. (1) When we breed dogs, we have no idea what we're doing on a genomic level, as we are only working with traits we find appealing, and (2) we breed animals and plants in an artificial environment with a skewed fitness function -- we don't know how the effects of our breeding programs would play out in the wild, and mostly we produce strains that can't compete in nature.

      Breeding fails to produce hardy strains because, genetically, it is a blunt instrument wielded by a blind man. That's why Dalmatians are stupid.

      This selection of eggs is different: we know what we're doing on a genomic level, and we're making choices based on a small number of genes linked to specific inheritable diseases. There is not yet any evidence that these disease-related genes are linked in any way to intelligence. We have some folkloric and statistical evidence linking intelligence to genetics, but we cannot yet identify any gene that differentiates an Einstein or Mozart from the average schmo.

      --
      WWJD for a Klondike Bar?
    8. Re:Evolution vs Breeding Out Intelligence by Syberghost · · Score: 2

      I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive. That's not an evolutionarily sound move on my part, but that's not going to make me dump my lovely girlfriend.

      I think that is an evolutionarily sound move on your part, because if you instead dated women who weren't attracted to fat, bearded computer geeks, you'd be arrested and fail to reproduce.

  20. This sucks... by Creedo · · Score: 1

    I question the very concept here. I wholeheartedly support eliminating these diseases, but I don't think we, as a society, have the ethical and moral strength to resist the inevitable temptation to abuse this(in fact, there are cases of it already happening). A person's worth is intrinsic, not based on their physical condition. Look at Stephen Hawking or Helen Keller. Imagine if they had been screened, and eliminated.

    Until we progress beyond the point of treating "personal responsibility" like a four letter word, we are simply too immature to play with these toys.

    Creedo

    --
    All that is necessary for the triumph of good is that evil men do nothing.
    1. Re:This sucks... by Anonymous Coward · · Score: 0

      > Look at Stephen Hawking or Helen Keller. Imagine if they had been screened, and eliminated.

      Yeah what if they had been screened out and what amounts to their siblings who weren't afflicted with either a neuro-degenerative disorder or born blind/deaf were born. The sibling probably wouldn't have grown up to be like SH for example. But if he/she had, then the expected (total and productice) lifespan for a brilliant theorist would be greatly increased. Sad but true, Helen Keller probably would have been a whole lot less effective if she didn't have what could crudely be called "freak value".

      I agree that it's a start down a slippery slope and we are probably too stupid to pick out good/sound criteria for culling out diseased.
      But then when has the fact that we, as a society are stupid stopped us from doing things?

    2. Re:This sucks... by Anonymous Coward · · Score: 0

      the only personal responsibility anyone feels is a five letter word: M-O-N-E-Y...

      this is, of course, a revolting attempt to create a market for "designer babies" as others have pointed out...

      indeed, I believe such knowledge are tests by the divine... do we think we can eliminate the undeniable source of life (call it whatever you want, God, Truth, the Universe) ?? When we think we can, the human experiment comes to an end...

    3. Re:This sucks... by Anonymous Coward · · Score: 0

      "A person's worth is intrinsic, not based on their physical condition"

      But if you really believe that, why does it bother you if the child is selected for some physical condition?

      Also I wonder if Stephen Hawking and Helen Keller (don't know her?) wouldn't have preferred to be healthy people if they had been given a choice.

    4. Re:This sucks... by Anonymous Coward · · Score: 0

      >>and Helen Keller (don't know her?)

      Helen Keller was a blind/deaf US child who managed to learn a modified sign language by touch. Eventually she learned to speak and gave several rather famous speeches. It's an amazing story of overcoming disability. Would she have preferred to be healthy -- depends on if she like herself.

  21. Utilitarianism by Daftspaniel · · Score: 0, Troll

    >implanted the eggs back in her womb.
    So, they put more than one baby inside her and one was born. I notice the submitter describes this as 'good'. Eugenics is BAD - yes even trendy 21st century Smart Eugenics. The inconvenient die for the sake of the Master Race.

  22. There are many other examples by Aelfweld · · Score: 2, Informative

    There was one which was part of the The Genomic Revolution at the The American Muesum of Natural History where a couple chose thier baby based on its ability to provide a necessary blood or marrow transplant to thier already born daughter that really struck me. Interesting but somewhat scary stuff.

    --
    Government is the abdication of your responsibility to a faceless bureaucracy. Anarchy(absence of government)is the a
  23. Family Ethics by gdyas · · Score: 1, Flamebait

    Sure, this is a good thing for the kid, but is it ethical for a doc to help a woman who's likely to be senile by the time her kids are in elementary school overcome such disadvantages and give birth, by any means?

    Well, guess it's her choice, bad though it may be. Just 10 years ago she might've just gotten a hysterectomy, adopted, and moved on. Personally, I just don't understand the NEED to have your own kids. In a world where needy kids need to be adopted, it strikes me as more than a little self-centered to see high-tech IVF methods as NEEDED so you can have YOUR baby.

    It's like the sow in the midwest that had 7 kids, half of them retarded. They weren't a sign from God, sweetie. The infertility was the sign from God. Whatever though. Do what you like. Just don't ever expect my insurance payments to cover it.

    --

    The only tool you've got against psychosis is experience.

    1. Re:Family Ethics by Kintanon · · Score: 2

      Just wanna give a little HELL YEAH, and ask you to e-mail me, I know a great website you should visit, but if I post the link here we'll end up with more ppl posting trollish pics on it and other crap. My above e-mail is correct.

      Kintanon

      --
      Check out JoshJitsu.info for Brazilian Ji
    2. Re:Family Ethics by nil_null · · Score: 0

      I agree.. I see everyone's desire to have a child as just a selfish desire they've been programmed with. I just recently visited India, whose population is through the roof. They are so stuck in their ways, people are basically expected to follow the same path: get married and have kids. If you don't follow this path they consider there to be something wrong with you. Why would people in a country with such a tremendous population problem continue with such nonsensical tradition? The reason I'm given is so that they have someone to take care of them in their old age. I guess their society is just that way. But then they ask me "when you are getting married?" and I say "not for a long time" (and think to myself "never" and laugh). Maybe I'll get married, but I don't have any intention of adding another child to this world.

    3. Re:Family Ethics by Anonymous Coward · · Score: 0

      Personally, I just don't understand the NEED to have your own kids.


      The whole purpose of our life; the entire reason that humans exist, is to propagate genes. Adopting doesn't accomplish that very well.

    4. Re:Family Ethics by lkaos · · Score: 2

      Personally, I just don't understand the NEED to have your own kids. In a world where needy kids need to be adopted, it strikes me as more than a little self-centered to see high-tech IVF methods as NEEDED so you can have YOUR baby.

      From an evolutionary standpoint, I have to disagree. "Designer Babies" are likely to come only from individuals who are amoung the more successful in society. There offspring is likely to be successful too.

      What we should be encouraging, is better birth control methods. Not preventing breeding of the more responsible in society in order to divert resources to the offspring of the less responsible of society. (Please note, yes there are always exceptions yada yada yada, but the above statement is correct for the majority).

      It's like the sow in the midwest that had 7 kids, half of them retarded. They weren't a sign from God, sweetie. The infertility was the sign from God. Whatever though. Do what you like. Just don't ever expect my insurance payments to cover it.

      Unfortunately, we your probably did do your part paying for it by purchasing the Time magazine they were in or by watching a television show they appeared on.

      The real travesty of it all isn't this woman's idiocy but rather all the woman who choose not to have selective abortions in similiar situations (in order to be famous) and end up having kids that die in a few days or live short, painful lives.

      I personally think that if a mother makes such a decision, and her children suffer because of it, she should be charged with manslaughter...

      --
      int func(int a);
      func((b += 3, b));
  24. Singularity by urubos · · Score: 1

    Finally we start down the road to the Singularity. I give it another 40 years till humans no longer exist. As I see it this (and the creation of AI) is the only way for our civilization to continue to grow without killing ourselves.

    --
    Anail Nathrock Uthvass Bethudd Dochiel Dienve
  25. Not worth it by Anonymous Coward · · Score: 0

    By the time such a kid figures out what slashdot is, Last Post will have long since been archived.

  26. Finally, taking steps towards evolution. by God_Retired · · Score: 2, Interesting

    I want to see genetic engineering just take off crazy and unregulated. Seriously, there are enough of us here, that the only way we'll REALLY fuck up is if we keep going the way we are.

    I want to see athletes engineered to run 25 miles an hour for hours on end.

    I want to see people with IQ's off any scale.

    Hell, I want to see decathalons with supped up athletes where half the contestants explode before the end.

    Bring it on, I like it and we need it. Fuck all you Naysayers in your nice comfortable existence.

    1. Re:Finally, taking steps towards evolution. by juggler314 · · Score: 1

      Exactly! As humans we strive to improve everything around us. We want to build faster processors, we study to become smarter, we want to make things faster and we want them cheaper. There is nothing we can do that we don't try and do better. Why wouldn't you want to make your children better??? Hell I hope before I die they figure out how to do gene therepy for a bunch of things so at least I can benefit from genetic engineering some if not as much as future generations. And for those of you who are about to say something about creative types not being for this that's not true either. Every artist I know strives to represent something in the best possible way, hence if I could help him do that better he would go for it. I however don't want to explode...

  27. this makes me a little uneasy by colmore · · Score: 2

    I have to say this is one area of technology I'm a little bit uncomfortable with. But then again, my family doesn't have a history of any genetic diseases.

    I think it's going to be a *long* time before we can screen for things like intelligence, the genetics behind such traits is too complex for the forseeable future. There is no geek gene.

    As long as this stays within the realm of selecting against life-threatening genes, I don't see too much of a problem.

    I'd also like to know why so much effort is spent on reproductive medicine for rich nations with near zero population growth and near zero infant mortality. couldn't our resources be better spent helping out the rest of the world control their populations, and improving the (shamefully poor) infant health services in those regions?

    I know it comes down to money, but still...

    --
    In Capitalist America, bank robs you!
    1. Re:this makes me a little uneasy by Anonymous Coward · · Score: 0

      >But then again, my family doesn't have a history of any genetic diseases.

      Are you sure? Most people are REALLY hard-pressed to go back to both grandparents, and not have SOMETHING bad that they can inherit. Diabetes, cancer, heart problems, arthritis, short-sightedness, propensity to cavities, the list is pretty much inexhaustible.

  28. Where do you draw the line? by Anonymous Coward · · Score: 0

    1) Screen for potentially harmful diseases, such as Alzheimer's, and prevent them.
    2) Test for other traits such as height and eye color, etc.


    This is a rather trivial example, methinks. What about "conditions" that are more ambiguous? Like abnormal height? Should we screen for anyone taller or shorter than "average"? And if so, who determines that average? What about average IQ? Will your doctor say "I won't provide prenatal care for or deliver babies that have an IQ less than X, because 20 years down the line I'll be liable for lawsuit when that kid sues me for not making him smarter"

    Like the subject line says, 'where do you draw the line?' I'm glad i'm not the judge who'll eventually have to rule on this one...

    1. Re:Where do you draw the line? by I+Want+GNU! · · Score: 2

      We draw the line at wiping out diseases that are potentially harmful.

    2. Re:Where do you draw the line? by Anonymous Coward · · Score: 0

      Is dwarfism a disease that is potentially harmful? How about autism? How about social anxiety disorder? What about premature balding? Obesity?

  29. Come and visit Ohio! by Anonymous Coward · · Score: 0

    I live in Ohio. Not just any Ohio, but THE Ohio; small town Ohio. It's really where the action is if you enjoy entertaining functions such as fish fries, tractor pulls, buggy races, or generally drinking yourself to death because the alternative is existing in a world where absolutely nothing happens.

  30. You can do it too by Anonymous Coward · · Score: 0

    make him your foe

  31. Typical cursory opinion by Marx_Mrvelous · · Score: 2

    You go on, but your point is pretty incoherent. Let me address several of your points: 1. This is the best type of natural selection. You say it "goes against" it, but this is the most aggressive type of weeding out bad genes. I can assume you mean that "naturla forces" should decide which traits are bad and not the parents, but you don't explicitely say this. 2. The issue here isn't government intervention. What if the governemnt waited for children to be born and *then* killed "undesireable" ones? It's a pretty stupid postulation, since it's simply not happening. 3. Adoption. There's a huge difference between being infertile, and potentailly passing a debilitating disease onto a child. Yes, there are many children up for adoption. But that doesn't mean someone wanting to have a biological child can't. Anyways, wouldn't adopting be going against natural selection in a MAJOR way? Some things to think about...

    --

    Moderation: Put your hand inside the puppet head!
  32. Stephen Hawking by aron_wallaker · · Score: 1

    OK, if we're in a situation of sorting through a bunch of eggs/sperm and trying to pick the 'best' one, then it may not seem like a big deal. A child is going to be born, the parents aren't going to change, we're just trying to tilt the table a bit as to one gene or another.

    Imagine that someone had gone to Stephen Hawking's parents and said 'well, you have a gene that makes your children more likely to have ALS (an admittedly terrible disease to have), maybe we should screen your eggs/sperm and filter that out'. Given that Hawking's gift of scientific understanding is so rare, could you assume that this would have no effect ?

    I know if I was about to become a parent and genetic testing told me my child would either have a terrible disease I would be horrified by the prospect...but I don't know that this is any way a 'right' thing to be doing. Think about Hawking, that's all I have to say.

    (Yes, I know, 'God does not play dice')

    1. Re:Stephen Hawking by Anonymous Coward · · Score: 0

      >Imagine that someone had gone to Stephen Hawking's parents and said 'well, you have a gene that makes your children more likely to have ALS (an admittedly terrible disease to have), maybe we should screen your eggs/sperm and filter that out'. Given that Hawking's gift of scientific understanding is so rare, could you assume that this would have no effect ?

      First, you're assuming that ALS has a corollary with intelligence. Once you show that, take it to the medical community. Until then, that argument is nothing more than an emotionally-stacked "Oprah" candidate.

      Besides... for every Stephen Hawking, there are *millions* of people with genetic mental disorders living lives of homelessness, alcoholism, hunger...

      steve

    2. Re:Stephen Hawking by Creedo · · Score: 1

      "Besides... for every Stephen Hawking, there are *millions* of people with genetic mental disorders living lives of homelessness, alcoholism, hunger..." And your point is? The original poster was not assuming a corollary between intelligence and ALS. Stephen's condition forced him to use his imagination more. I would say that his environment certainly helped shape his creativity. Creedo

      --
      All that is necessary for the triumph of good is that evil men do nothing.
    3. Re:Stephen Hawking by aron_wallaker · · Score: 1

      My point was that although we're at a point where we may be able to (very) manually filter a group of eggs based on one or two genes, we're nowhere near being able to look at all the genes at one time. So while we're being overfocused on what we think is important - Alzheimers, ALS, whatever - there's no telling what we're missing.

    4. Re:Stephen Hawking by Anonymous Coward · · Score: 0

      Imagine that someone had gone to Stephen Hawking's parents and said 'well, you have a gene that makes your children more likely to have ALS (an admittedly terrible disease to have), maybe we should screen your eggs/sperm and filter that out'. Given that Hawking's gift of scientific understanding is so rare, could you assume that this would have no effect ?


      And this is bad how? Ask Stephen Hawking if he would give up his above average intelligence to be able to walk. Don't be so fucking selfish.

  33. I can already see one group getting upset by aCapitalist · · Score: 0
    A while back there was a story on one of those news shows that had a deaf child getting some kind of new fangled implant so that it could hear. Some militant deaf activists got up in arms because they proclaimed that "there is nothing abnormal with being deaf".

    I wonder if this same group will throw a tantrum if people start screening for the gene that causes deafness.

  34. Wouldn't this be, like, 0.6? by lblack · · Score: 3, Funny

    I dunno about you, but I don't release a version 1.0 until I test the completed product for deficiencies. So, we probably won't be hitting 1.0 for at least 20 years (post-puberty functions have to be checked into).

    In other words, right around the same time Mozilla and OpenOffice hit it!

  35. A Good Book About This Whole Issue... by tigris · · Score: 1

    ...(well, actually, it's a whole series, but the first book is the best) is Nancy Kress's "Beggars in Spain". It's a very entertaining and thought-provoking story about what might happen when genetic modification for socially-desirable traits becomes more widespread (i.e., available to the wealthy).

    While I myself would love the ability to survive without sleep (Kress's example) as well as perfect hearing and eyesight, genetic engineering to create more "desirable" children has the potential to make the current divide between the rich and poor seem microscopic in comparison to the gap that will emerge once the rich can create "ideal" children with a fair degree of accuracy.

    Genetic tweaking of offspring will have to be made available to everyone, rich or poor, otherwise class warfare won't be just a matter of politics.

    Tig

  36. So now a healthy baby with an unhealthy mother? by spicyjeff · · Score: 2, Insightful

    So the mother has an ailment which means by the time she is 40 she will become senile. The child will just be 10 years old at that point. How is a senile mother supposed to raise a 10 year old child? Once again selfishness of the parent seems to have won out over long term best interests for the child.

    1. Re:So now a healthy baby with an unhealthy mother? by Anonymous Coward · · Score: 0

      I agree! Why don't you bravely volunteer to help raise it? No? Shut up.

    2. Re:So now a healthy baby with an unhealthy mother? by Anonymous Coward · · Score: 0

      This kind of comment makes me sick (german newspapers also reported about this argument). First of all, there will still be the father to raise the child. Also, we all die sooner or later - perhaps nobody should have children, because eventually they will all be parentless. Who knows, those parents could also make sure that there are other people who will care for the child - a much better situation than a child that loses both parents due to an accident or whatever.

      Are you aware that your point is nothing but a reformulation of eugenics?

      Much as it might seem desireable that everybody grows up with a standardized family, I don't even think it would be a good thing. Diversity is a good thing, so people having different backgrounds and life experiences is a good thing. That child might suffer from losing her mum so early, but she might also become a special person because of it (especially if her parents prepare her for it). Plus, does she not have a right to live just because she'll lose her mother sooner than other people?

    3. Re:So now a healthy baby with an unhealthy mother? by Anonymous Coward · · Score: 0

      And to pick up the Stephen Hawkings argument that seems to be popular in this discussion: perhaps losing a mother to alzheimer at the age of 10 might have a similiar effect on the child as having ALS (or what's the deseases name?) had on Stephen Hawking? In other words, by denying a child to be born because she will lose her mother by the age of then, you might be denying a new super genie it's existance.

    4. Re:So now a healthy baby with an unhealthy mother? by Anonymous Coward · · Score: 0

      He's pointing out that they went through great lengths to prevent this child from have to deal with one tragedy so why don't they realize that they are going to face another?

      Once you start meddling its a slippery slope, where do you stop trying to predestine the child's life and let them life there own experiences and learn from them?

    5. Re:So now a healthy baby with an unhealthy mother? by Anonymous Coward · · Score: 0

      And you can use tha same argument to say that by denying the child the 50/50 chance of contracting a genetic disease you are denying their true existence.

    6. Re:So now a healthy baby with an unhealthy mother? by SecurityGuy · · Score: 2

      Plus, does she not have a right to live just because she'll lose her mother sooner than other people?


      No, not when you're talking about potential people rather than actual people who already exist. The question is, should this family endeavour to create a child who is destined to suffer the early loss of a mother. The question is not should a pregnant mother in such a case abort. Attributing a right to live to potential people quickly becomes ridiculous as we must consider every menstruation of every woman on the planet every month as carrying a fertilizable egg which had a "right to live".


      Of course we all die, but most of us don't have a decent estimate of how much time we have left. If I had 10 years left, I think I'd opt to spare my potential children the terrible trauma of losing a parent.


      You do an excellent job of pointing out, unintentionally, I'm sure, the silliness of the "diversity" crowd. Diversity is absolutely not, on its own, a good thing. We're not a better world because we have people with AIDS and people without, people starving to death and people with enough to eat, terrorists and pacifists, and the list goes on. Better we cure aids, end hunger, and get rid of the crackpots. Nope, thanks, but I feel confident you'd have to search quite a long way to find someone (aside from abused kids) who thought the death of a parent during childhood was a good thing.

    7. Re:So now a healthy baby with an unhealthy mother? by Thing+1 · · Score: 1
      How is a senile mother supposed to raise a 10 year old child? Once again selfishness of the parent seems to have won out over long term best interests for the child.

      Your question is valid whether or not the mother used a process to eliminate bad genes in her child.

      Which means your conclusion is inappropriate. The "long term best interests for the child" are gone either way once the child reaches 10. With that in mind, wouldn't it be better for future generations to eliminate senility? Either way the immediate next generation is screwed.

      But using this technique, her grandchildren will not have senile parents. Ignoring this technique, history will continue to repeat itself.

      I applaud her decision.

      (Or were you trying to say that in your world, she would simply not reproduce?)

      --
      I feel fantastic, and I'm still alive.
    8. Re:So now a healthy baby with an unhealthy mother? by spicyjeff · · Score: 1

      Yes I guess that is what I am saying. Call me old fashioned but natural selection coupled with selflessness decisions I believe are the best way.

    9. Re:So now a healthy baby with an unhealthy mother? by Thing+1 · · Score: 1
      Please describe a decision that is made selflessly. I'm serious -- I can't think of one myself.

      Every decision I make is geared toward my survival. This is, inherently, selfish.

      --
      I feel fantastic, and I'm still alive.
  37. Not the first time by shellac · · Score: 2, Informative

    Many people seem to think that this is the first time preimplantation genetic diagnosis (PGD) had been used. I will quote from the first paragraph of the JAMA article to clear this up:

    According to the most recent review, preimplantation genetic diagnosis (PGD) has been applied to at least 50 different genetic conditions in more than 3000 clinical cycles. In addition to traditional indications, similar to those in prenatal diagnosis, PGD was performed for an increasing number of new indications, such as late-onset disorders with genetic predisposition and HLA testing combined with PGD for preexisting single-gene disorders. These conditions have never been an indication for prenatal diagnosis because of potential pregnancy termination, which is highly controversial if performed for genetic predisposition alone. With the introduction of PGD, it has become possible to avoid the transfer of the embryos carrying the genes that predispose a person to common disorders, thereby establishing only potentially healthy pregnancies and overcoming important ethical issues in connection with selective abortions.

    Basically, it says that PGD has been used for predispositions to diseases that come later in life before. This is just the first time it is being used for this particular disease.

    The thing that possibly makes it more controversial is that not all of the people with the genetic mutation they "weeded out" go on to develop Alzheimer's, for reasons that are unclear. So maybe they trashed some perfectly OK embryos?

    1. Re:Not the first time by spicyjeff · · Score: 1

      They weren't embryos. They were unfertilized eggs from the mother who carried the gene.

  38. good times by dimitri_k · · Score: 1

    According to the article, 23 eggs were screened for the disease. Of those, 15 were fertilized. Of 15 resulting embryos, 4 were transferred to the uterus. Of the 4, 1 was term.

    That is 14 discarded embryos for 1 term pregnancy for a mother who will have Alzheimers by the time her kid is in middle school.

    What a wonderful story. Really warms the heart.

    --
    sig is
  39. White Babies by Knunov · · Score: 2

    Adoption isn't as easy as you think.

    Try and adopt a healthy, White baby and you can expect to wait in line for years. And even then you better be a straight, financially stable, heterosexual couple, otherwise, forget it.

    Now, if you want a Black or Asian child, homegrown or imported, there are plenty to be had.

    But people don't seem to want those kind...

    Moderators: This should be modded down as Offtopic, even though it isn't, really. Troll or Flamebait doesn't apply because what I said is completely true, and you know it.

    Knunov

    --
    Why do users with IDs under 100,000 or over 700,000 usually have the most worthwhile comments?
    1. Re:White Babies by d-e-w · · Score: 2, Informative

      Now, if you want a Black or Asian child, homegrown or imported, there are plenty to be had.

      But people don't seem to want those kind...


      Not exactly. In several states (that I know of/have experience with) a white family can not easily adopt a black child. The state would prefer the child stay in foster care until an adoptive parent "of their own culture" is located.

      Never mind that the majority of these children don't come out of foster care until they reach age 18 ...

      Finances and legality do stand in the way for Asian and Eastern European adoptions, too. I know several people who have participated in Asian adoptions (from China) which took upwards of a year, and between $50K-$100K. Supposedly there are NFP groups that will help with finances at now (these adoptions are all several years in the past now), but you're still talking about a large financial commitment.

      In many cases, medical insurance *will* pay for infertility treatments (and pregnancy), but little will help you pay for adoption.

    2. Re:White Babies by raldanash · · Score: 1

      Most people want children that look like them. Part of it is also that that way the fact that the child is adopted is a lot less obvious. Part of it just because people generally do have racial feelings, no matter how much you might want to deny it.

      In an ironic note, many of the "black" babies that can't be adopted by white parents do to "cultural genocide" are often half-white. Of course, the rule of hypo-descent (that all people with a drop of black ancestry are black) rules in this case.

      And before we get to criticizing American whites....remember that in Korea the reason there are so many kids that come to the US is that people are reluctant to adopt someone and have descendants outside of their bloodline. The Korean government is trying to change this attitude, but it's pretty hard.

      --
      NO gods, NO governments, NO [OPTION]....
  40. Terminology beats thought by joss · · Score: 5, Insightful

    Just using that phrase "designer babies" determines the conclusion. Put out a poll...

    "are you in favor of designer babies" - no

    "should potential parents with inheritable diseases have the right to pre-screen their embryos for those diseases" - yes

    Then we get the "look at all the wonderful cripples like Hawkins etc...." argument. Well, the foetuses you discard have at least as much chance of turning out well as the ones you keep. There are plenty of great humans who have nasty genetic diseases, but we have no way of telling what geniuses we've missed because the lack of screening meant some doomed half-wit runt got born instead.

    And while I'm ranting... Gattaca wasn't that scary. I'm in favor of a world where more people look like Uma Thurman.

    Anyway, I better quit before I start proposing full scale eugenics and saying "just because Hitler gave it a bad name doesn't mean it's wrong, after all, if his policies had been implemented Hitler would never have been born in the first place..." that would ruin any credibility I have. Oh shit, too late, just kidding, but I do have a gut reaction against the "this is what nazi's wanted = bad". Decent roads and punctual transport would get discarded too with those arguments.

    Personally, I have more faith in nature combining things in the right way than a bunch of fuckwit genetic engineers. But, I don't think it's fair to tell people "it's illegal for you to try and avoid having a child who dies early - I'm not comfortable with that". You know what - nobody asked you to be comfortable with it, it's none of your business.

    --
    http://rareformnewmedia.com/
    1. Re:Terminology beats thought by mav[LAG] · · Score: 4, Funny

      Just using that phrase "designer babies" determines the conclusion. Put out a poll...
      "are you in favor of designer babies - no"
      "should potential parents with inheritable diseases have the right to pre-screen their embryos for those diseases- yes"


      Don't forget option #3:

      "Not sure - just as long as it doesn't look like CowboyNeal"

      --
      --- Hot Shot City is particularly good.
  41. yu whore by Anonymous Coward · · Score: 0

    you suck bitchdyhwoe

  42. This is fine until... by rackhamh · · Score: 1

    ... insurance companies start charging more for people who were not prescreened. They could do this under the (admittedly reasonable) pretext that prescreened people are less likely to develop unexpected illnesses down the road.

    Health care is already expensive, and this would most hurt exactly the same people who can't *afford* prescreening.

    Also, it scares me to think that rich people will be weeding out bad genes while poor people continue to get sick. The social implications are frightening.

    That said, I do think this sort of screening is a good idea. Any chance to reduce suffering in the world is a good thing. We just need to be *very* careful about how we apply it.

    Shades of Gattaca, indeed.

  43. No nigger by Commienst · · Score: 0

    Ain't no nigger like the one I shot!

    Yeaziah! Biatche!

    --

    I am into the copy and paste.
  44. A few reality checks by nanojath · · Score: 2
    There are scary inmplications but I think it needs to be viewed in context. For starts, a lot (I will hazard a guess at a majority) of people will simply reject this or be priced out of the possibility. You have to accept in-vitro for starts, I suspect it's going to be a lot harder to type sperm, so you still have some serious uncertainty there. And while some traits and diseases will yield easily to genetic typing, others, particularly complex ones like intelligence or athletic ability, will not. And is it worth 10s or 100s of thousands of dollars to have a kid with blue eyes?


    Yeah, yeah, the gentic superclass of the wealthy. Big deal, they're already a superclass in terms of quality of life and survival due to simple wealth. And remember, they're still confined to the leash of their personal genetics.


    We don't know nearly as much about genetic impact on traits and development as we sometimes like to pretend. It's highly likely that more devlopment occurs in the womb than many people acknowledge - pure environment, and the kind that is hard to account for in the kinds of population studies that end up defining our assumptions about what traits are genetic.


    "It's against evolution and/or natural selection!" It's amazing, I've heard it a million times and it still makes me laugh. No baby, it is Evolution AND natural selection if anything is. Evolution occurs on a time scale that, whatever we may say, defies our attempts to truly understand the consequences of our present actions. There's no such thing as a bad or good adaptation in it: some individuals pass on their genetics and some don't: end ah' fuckin' story.


    In the Gattaca world I probably wouldn't exist, what with the bad eyesight and predisposition for substance abuse and all the rest. I'll be passing on my genes anyway if I have anything to say about it, the old-fashioned way, thank you very much, and another fucked up kid will come into this world. I'll put mine up against a superbaby any day.

    --

    It Is the Nature of Information to Transgress Artificial Boundaries

    1. Re:A few reality checks by chompz · · Score: 2

      What I'm more worried about is the super-rich creating a class of super-stupid laborers. These lower class laborers would work for a cheap meal and tolerate living in a dog cage. They would be intelligent enough to count things, work a field by hand, and do hard labor. There would be no need for the genetic upper class to work, because they have created the genetic middle class to manage the genetic lower class while happily living in the same solitary confienment as the genetic lower class. A few people could manage the whole thing and litteraly rule the whole world. Think about how that would fuck up everything that you have and say that this should be incouraged. It will happen, people will be really designing thier children, but it should not be incouraged.

      --
      Spring is here. Don't believe me, look outside!
    2. Re:A few reality checks by nanojath · · Score: 2

      You're reading too much science fiction friend. Do you honestly think the situation you describe is any different from the current world situation? If a person has no power and no wealth then their intelligence is irrelevant. As things stand the majority of people are working for little more than the equivalent of a cheap meal, in living arrangements scarcely better than cages, making our cheap commodities. Child and slave labor are alive and well all over the world. Why spend billions on genetic engineering when the impoverished labor class constantly refreshes itself for free (and takes care of its own offspreing)? Meanwhile, engineering a labor cost would expose the wealthy to the liability of responsibility for its labor force: at the moment the ideology that "they're getting the deal they agree to" absolves the wealthy 5% of humanity from any sense of responsibility for the miserable lives of those who create their wealth. You really want to improve the world you might spend less time worrying about the long term implications of screening eggs for alzheimer's and a little more thinking about who assembled your fucking shoes.

      --

      It Is the Nature of Information to Transgress Artificial Boundaries

    3. Re:A few reality checks by AndrewCox · · Score: 1

      If you could write well and thought of that about 75 years ago, you could've come out with a classic sci-fi anti-utopian book!

      --
      The Red Pill ... all I'm o
  45. A pretty good thing on average by Nurf · · Score: 5, Insightful

    I think being able to adjust ourselves genetically is a good thing on average. We just have to be careful that we dont:

    1) Decrease the overall genetic diversity of the population. ie. Mass produced specific genes are probably a bad idea.

    2) Create people that can't mate with "normal" humans.

    As long as (2) applies we are adding to the gene pool, and it think there are enough people having kids the natural way out there that (1) will be very difficult to make happen (gene-implanting virus epidemics aside).

    The possibility exists that a modification could be made that ends up having bad consequences for the recipient decades later. This is the nature of reality. The risk means that people will think twice before doing it, which should provide some handy negative feedback. You have to consider the probabilities.

    Would I be willing to make this choice for my offspring? Yes. I indirectly make this choice by picking a mate anyway. I won't make a choice carelessly, and I would only do it if I saw real benefit for my kids. Many choices you make in your lifetime have a significant impact on those around you. It's the nature of life, rather than the nature of this particular problem.

    For those that would point out that my children would bear the lifelong burden of my choices, I agree and say "So what?". It would be one of many such choices, and I feel no moral qualms about making them. It is my responsibility to do so.

    Just to be clear, I know we are currently in the "remove things we know to be bad" stage rather than the "designer water-breathing" gene stage. I'm just looking ahead a bit.

    I find most of the complaints against this sort of thing to be in the gut-feeling-looking-for-a-pseudo-logical-argument category. The remainder have so far made points that haven't convinced me.

    --
    ---
    1. Re:A pretty good thing on average by GrimSean · · Score: 1

      The way our current culture is operating - ie on a global scale - a decrease in the overall genetic diversity of the population is impossible to avoid. The more 'random mating' that takes place, the more homogenous a species' genes become is a nice little Genetic rule that our species is merrily putting into action.

      In response to your second point, the definition of a species is a group of organisms that can mate with each other creating viable offspring (viable being the operative word). If we made something that couldn't produce offspring with us, it would no longer be a member of the good old Homo Sapiens species.

      As to your statement about making 'modifications' to your childrens somatic genes being akin to your choice of a mate, I can only say "no". When two people get together and have kids, they are intermingling their own genes, which quite obviously have worked out well, and are passing them along to their children. These genes have worked out pretty well throughout our species' lifetime, and the odds are they'll work for our kids. I don't believe that at our current state of knowledge about our genes, or even quite honestly 50 years down the road, we will know enough to be able to say that through mucking about with genes we can assure healthier offspring past that first generation that is modified. I for one do not have the convictions to sentence my grandchild to the n-th degree to some horrible genetic disease caused by our wanting to weed out freckles or male pattern baldness from our gene line or some other frivoulous thing. The unfortunate thing is that our species is quite long lived, and the means that any genetic manipulation done to our DNA may seem stable at first, but it could be potentially deadly when puberty begins.

      I would, however, probably do someting along the akin to the article that spawned this discussion if it became available for my children. No genetic manipulation was undertaken in it, only genetic screening for a known genetically related disease that ran in the family. Of course, twenty years down the line a virus might come along that kills people carrying that gene, but that's what happens when you subject yourself to nature.

      --
      I don't need to be made to look evil. I can do that on my own. - Christopher Walken
  46. What happened to the other 22? by linatux · · Score: 0

    ... washed down the sink? Unless we learn respect for life, we will all suffer the consequences.

    1. Re:What happened to the other 22? by Anonymous Coward · · Score: 0

      It's not life you fuckwit. It's half of a life. Do you save your gizz when you rub it out? That's just as much a life as an unfertilized egg. Read the fucking article before pull the Right to Life speil, ok?

    2. Re:What happened to the other 22? by linatux · · Score: 0

      My mistake - comment based on a different (less detailed) article. Thank you for your eloquent, light-hearted correction. I am pleased to see we agree on the principles of life.

  47. screened "weakness" may contain necessity by Splork · · Score: 2

    we do not know enough about the genetic code to determine what is and isn't a weakness in the long term gene pool. this is very dangerous for the species. or at least any of the species rich enough to pay for such procedures... hmm.. this problem may correct itself.

  48. What happens when a weakness is a strength? by AutumnLeaf · · Score: 1

    This is a "what if" question. But basically, it should be noted many of the problems/diseases we screen for are considered weaknesses in the context of our society. What if part of the overall strength as a species is the good and the bad put together?

    To word it differently, what if we mistakenly classifly a positive as a negative based on our perception of it, and then breed that out of ourselves (long term, given a gattica-like future)? And what if our environment changed such that a former weakness is now a strength?

    That being said, I'm all for screening for some of those nasty problems out there. I just hope someone is looking at the "big picture."

    1. Re:What happens when a weakness is a strength? by NerveGas · · Score: 2

      >To word it differently, what if we mistakenly classifly a positive as a negative based on our perception of it,

      A classic example is obsessive-compulsive disorder (OCD). If you look at highly succesful doctors (and those in other demanding professions), a very high percentage of them have a detectable level of OCD... in very tiny amounts, it can be a really helpful thing. But it doesn't take much at all before it can quickly turns into a very BAD thing.

      steve

      --
      Oh, you're not stuck, you're just unable to let go of the onion rings.
  49. Abortion still involved... by kbonin · · Score: 3, Informative

    While the Post article states:

    "He used molecular tests to identify which eggs were free of the genetic mutation, fertilized them with her husband's sperm and transferred four of the resulting embryos to her uterus."

    the JAMA abstract (which is likely correct) states:

    "Analysis undertaken in 1999-2000 of DNA for the V717L mutation (valine to leucine substitution at codon 717) in the APP gene in the first and second polar bodies, obtained by sequential sampling of oocytes following in vitro fertilization, to preselect and transfer back to the patient only the embryos that resulted from mutation-free oocytes."

    This means that fertilized eggs were destroyed, which meets most definitions of abortion.

    1. Re:Abortion still involved... by kbonin · · Score: 2

      How is it "Flamebait" to correctly point out that one of the sources misrepresented the procedure, and back that assertion with direct quotes from the source?

      Someone is abusing moderation to editorialize.

    2. Re:Abortion still involved... by Darwin_Frog · · Score: 1
      This is no more abortion than what happens to unused embryos at fertility clinics is abortion. The clinics routinely destroy embryos that are no longer necessary.

      If implantation in the uterus has not occurred, it's not an abortion.

    3. Re:Abortion still involved... by Anonymous Coward · · Score: 0

      This means that fertilized eggs were destroyed, which meets most definitions of abortion.

      Admittedly, dictionary.com isn't a very scientific source of definitions, but: "Termination of pregnancy and expulsion of an embryo or of a fetus that is incapable of survival." There was no pregnancy, so I believe most definitions of abortion would not be met. Some would, I'd imagine.

    4. Re:Abortion still involved... by Derkec · · Score: 2


      This is most often the case in in-vitro fertilization. You can't attack this research on abortion grounds unless you attack the more general process as well.

  50. Natural Selection by Microsift · · Score: 1

    You are arguing for the preservation of "bad" genes in the name of natural selection? You seem to be at cross-purposes. Natural Selection is all about removing "bad" genes from the gene pool. This gene is sneaky in that it does not adversely affect the individual until after prime reproductive years. Your upset that we've outsmarted the sneaky gene, and are removing it from the pool(at least one instance of it anyway.) I think the poster correctly identifies this as a good outcome, that portents an ominous future. Adopting and raising other people's children is nice, but from a biological standpoint, it's not "what it's all about" We're wired to spread our genes, and promote their development, altruism can override this(and that is certainly admirable), but ultimately we live to preserve our genes, not a stranger's.

    --
    My other sig is extremely clever...
  51. Gattaca; great movie, bad analogy. by kavi_3 · · Score: 1

    I am getting sick of people using movies as an example of why something is good/bad. Gattaca, while a fine film is not useful in evaulating this kind of ethical dilemma. In fact, I would argue that Gattaca was less about the dangers of genetic manipulation an more a movie about ability of the human spirit to overcome adversity, especially artifical social barriers. The device could have been a racial caste system, poverty, or anything along those lines. They just happened to choose genetic engineering because it is topical.

    --
    "Attention Citizens, 2+2 now equals 3.947547175. Please recalibrate your equipment now" --The Computer
  52. sickle cell by Anonymous Coward · · Score: 0

    Just like Animal Mother said in Full Metal Jacket:

    "... thank god for the Sickle Cell"

  53. Give it time. by Spamalamadingdong · · Score: 4, Insightful
    Very simply, you can't screen for most human traits. Period. Sorry, go to the back of the line.
    Yet. The number of tests is going up rapidly.

    The real difficulty you're going to have is that the number of usable gametes you're going to get falls exponentially with the number of chromosomes you're trying to select for. After you get to four or five traits you've got a choice: either you're going to have to be able to pick individual chromosomes and build custom nuclei, or you're going to have to select a "best-of-N" instead of a pure optimum. The "best-of-N" preserves large elements of chance.

    Besides the fact that most traits are caused not by one gene, but by the interaction of dozens of genes and the proteins they create, you have to consider that almost all human traits develop in accordance to someone's environment.
    This is still not bad. If it gives parents a shot at having a child who'll do best in their environment, or allows parents the knowledge that their child will do best if they provide a certain environment, it's all for the better. The same tests which show what environmental influences are best will help children who aren't specifically selected for certain traits to get the best out of what they've got. This is coming whether you want it or not; the technology is essential to tell what drugs will benefit individuals and what side effects they might have, and the other knowledge will follow behind it. Soon we are going to have the knowledge once reserved to deities, whether we want it or not; we had better be prepared to act on it humanely.
    1. Re:Give it time. by markmoss · · Score: 2

      Very good point. To select for one particular combination of 20 paternal genes requires screening over a million sperm. If we understood what all the genes do, we'd probably want to screen 100 of them -- that's 10^30 possible combinations, and I doubt anyone is going to produce that many sperm in one lifetime. And on the ova side, the choice is probably always going to be limited to the best in a few dozen. This does leave lots of room for chance.

      Or we could use a very tiny needle to pick out the best set of chromosomes from a limited sample, and insert them into one egg or sperm. In this case the "chance" factor is the random damage caused by the manipulation... I think I'd rather just have my sperm filtered to somewhat reduce the prevalence of genes for shortness, weakness, and extreme nearsightedness. Unless they are tied to intelligence, that is, because I'd have no idea how to raise a big, strong, dumb kid.

      My biggest concern is that the primary selection criteria are likely to be negatives, that is "bad" genes to be eliminated (starting with early Alzheimers), and this will reduce genetic diversity, while possibly losing some apparently bad genes before the good side of them is discovered. Face it: if a fatal disease-causing gene occurs in the population often enough for the disease to be identified, there must be or have been some selective advantage to it to balance the disease aspect. Example: one sickle cell anemia gene makes you nearly immune to malaria, two kill you. Hence it's fairly common in certain areas of African where everyone gets infected with malaria, and it's still killing Americans whose 10 x grandparents came from Africa. Tay-Sachs and many others must have some similar advantage in particular environments, but we don't know what it is. What are we losing when we eliminate those genes?

  54. Ethical qualms??? by raldanash · · Score: 1

    What really irritated me about a lot of the reporting of the stories was the so called "ethical problems" implied by a women who might not be around in full mental-state for daughter's teen years. One idiotic commentator at the end of one article wondered, "...if having children was an absolute right in the light of the situation." Good question to ask, but how many idiots out their have kids in messed up situations??? 70 year old fathers, crack-addicted welfare mothers, the Yates psychotic-muderer and so forth. The only reason the "mainstream" press and its fellow-travellers point the finger at this women is because she used genetic screening-if they wondered if a crack addicted mother should have a right to have a child, everyone would be howling about civil liberties and the implied racisim.

    That being said-it is a concern that she chose to have a biological daughter. The child's life probably won't be optimum. But then again, what about lesbians having children? Or people that don't get themselves tested for life-threatening diseases that there's a family history for? And so forth. It all smells of rank hypocrisy and pious finger-pointing obscuring the real moral issues presented, because the woman's decision has ramifications about the choices that everyday people make, not just those who use genetic screening.

    --
    NO gods, NO governments, NO [OPTION]....
  55. Slippery slope by Anonymous Coward · · Score: 0

    Hi geniuses,

    don't give in to a slippery slope argument.
    screening for diseases is completely different than adding super-powers. And besides, what is
    so bad about super-powers anyway?

  56. Oh dear. by Rupert · · Score: 2

    I invoke Godwins Law.

    Slashdot is now dead.

    --

    --
    E_NOSIG
    1. Re:Oh dear. by Tetrad69 · · Score: 2, Funny
      Godwin's Law prov.

      [Usenet] "As a Usenet discussion grows longer, the probability of a comparison involving Nazis or Hitler approaches one." There is a tradition in many groups that, once this occurs, that thread is over, and whoever mentioned the Nazis has automatically lost whatever argument was in progress. Godwin's Law thus practically guarantees the existence of an upper bound on thread length in those groups. However there is also a widely- recognized codicil that any intentional triggering of Godwin's Law in order to invoke its thread-ending effects will be unsuccessful.


      Sorry, no dice. ;)
  57. Easy to talk about, if YOU aren't affected! by Anonymous Coward · · Score: 0

    Yeah, it's really easy to talk all about the ethics of this when you aren't affected. But if you were able to live life with Tourette's Syndrome (or any of the many conditions that are much worse), then your point of view changes DRAMATICALLY.

    1. Re:Easy to talk about, if YOU aren't affected! by Creedo · · Score: 1

      Amazing how few seriously handicapped people disagree with you. Go ahead and ask them if they think they would be better off not existing.

      --
      All that is necessary for the triumph of good is that evil men do nothing.
    2. Re:Easy to talk about, if YOU aren't affected! by Anonymous Coward · · Score: 0

      What are you talking about? Did you even bother READING THE ARTICLE? It's talking about gene selection, not eugenics, you brain-dead idiot.

      And I *do* have Tourette's. And you're right, I don't wish that I didn't exist. But I wish that YOU didn't exist.

    3. Re:Easy to talk about, if YOU aren't affected! by Anonymous Coward · · Score: 0

      And I *do* have Tourette's. And you're right, I don't wish that I didn't exist. But I wish that YOU didn't exist.

      Swear at him! I saw this kid on a tv show with tourette's and he kept saying how he "WAS A BLACK MAN WORKING INCOGNITO!" Fuck, that's awsome.

    4. Re:Easy to talk about, if YOU aren't affected! by Anonymous Coward · · Score: 0

      Copralalia (compulsive swearing) is just one of the myriad of effects that Tourette's can cause. Not everyone with Tourette's gets it, it just stands out in your memory a lot more when you see a guy swearing at the top of his lungs than when you see someone tap their foot repetitively for a while. It's also the one that they're always SURE to put on the idiotic day-time talk-shows. The way they present them, those shows are usually more degrading to the kids than anything else.

    5. Re:Easy to talk about, if YOU aren't affected! by Creedo · · Score: 1

      Eugenics(from Merriam-Webster): a science that deals with the improvement (as by control of human mating) of hereditary qualities of a race or breed Oh my, that includes gene selection! It is eugenics on a family level. Welcome to the clue store. Feel free to purchase one. Creedo

      --
      All that is necessary for the triumph of good is that evil men do nothing.
  58. I genetically modified my penis! by Anonymous Coward · · Score: 0

    Now the monster is out of control!

  59. How options become manditory... by JohnDenver · · Score: 2

    I think all of us agree that the government shouldn't be force a manditory DNA screening for everybody, and to be honest I don't really see that happening in my lifetime. I would pray for the poor SOB politician who even decided to bring something like this to the floor.

    However, I can see screening becoming more and more popular for those who choose not to procreate naturally (having sex) to gain the benefits of potentially avoiding a limiting precondition.

    You wrote:
    What happens when the governments start screening every child that is born for any inherent form of "weakness"? Will those children never receive the chance to live? Will they be branded "inferior"? This has the potential to be an extremely bad thing.

    As far as your scenerio is concerned:

    * Why do you mention screening of children *after* fertilization when we're talking about screening eggs *before* conception even takes place?

    * What value would it be to the government to screen children for weaknesses after the fact if you can't change it?

    * Why do you conclude that screening before conception will result in manditory DNA screening?

    * If a child is intentified to have a "weakness", how is this a potentially bad thing?

    * Wouldn't discrimination laws apply to genetic predispositions?

    * Wouldn't intentifying the weakness allow health professionals to make provisions for that child?


    --
    "Communism is like having one [local] phone company " - Lenny Bruce
    1. Re:How options become manditory... by CTho9305 · · Score: 1
      If a child is intentified to have a "weakness", how is this a potentially bad thing?
      you really want to bring your child into the world KNOWING that they're going to suffer debilitating mental illness halfway through his/her life? you are one sick person.

      Wouldn't intentifying the weakness allow health professionals to make provisions for that child?
      see above. sure, we can make an alzeimers victim as comfortable as possible, but they will still get sick. and probably have to live their life KNOWING how it will end up. once again you are sick.

      or religious, in which case you believe that this isn't cruel, everyone should have an opportunity to suffer and everyone, regardless of fitness is created equal.

      I see NO short-term disadvantages to choosing an egg that doesn't have alzeimers. long term, there is a "disadvantage" since selection will cost money, and as a result, those who are presently rich would evolve "better" than the poor. we aren't at a level yet where characteristics like intelligence could be selected, but that day will most likely come.

    2. Re:How options become manditory... by JohnDenver · · Score: 2

      Slow down there horsy... I'm trying to figure out how the hell you read so much into my questions, especially to call me sick. Are you a jealous woman or do you miss key words when you read someone's post?

      To remove all doubt: My opinion is that I believe people should have the right to select whatever method of conception: natural (f%cking), or selecting eggs and sperm if they so choose, as long as it is for the benefit of the child and the child's quality of life.


      you really want to bring your child into the world KNOWING that they're going to suffer debilitating mental illness halfway through his/her life? you are one sick person.

      we can make an alzeimers victim as comfortable as possible, but they will still get sick. and probably have to live their life KNOWING how it will end up. once again you are sick.

      or religious, in which case you believe that this isn't cruel, everyone should have an opportunity to suffer and everyone, regardless of fitness is created equal.

      Should this logic apply to kids who have been diagnosed with cancer? (I was talking about screening after the child has exited the womb as was suggested in the original poster's scenerio)

      Identifying the chances of schizophrenia and telling a kid they are going to be schizophrenic are two different things, but you stumbled on a good question. Kids are told when they are diagnosed with Cancer, if you could diagnose schizophrenia, which can be a hellish nightmare, *when* should you tell your kids? (HINT: It's not really an issue of IF, it's a question of when they are mature and adaptive enough to handle the hard truth)

      --
      "Communism is like having one [local] phone company " - Lenny Bruce
  60. Here, have a clue by return+42 · · Score: 1
    Designer Babies, Version 1.0

    God. Slashdot. Typical clueless headline writing.

    Wake up, guys. Doctors have been screening for genetic diseases for years. Remember the big Tay-Sachs screening? The difference here is that it's a disease that won't show up until adulthood. Up to now they've only done lethal childhood diseases.

    Don't ask me why people are getting in such an uproar over that. Yes, I agree it wasn't necessarily a good idea to have a kid when you're going to go gaga in about ten years (he said tactfully). But as for the genetic engineering aspects, don't look for Gattaca anytime soon. Picking out one gene that causes a disease and selecting the gametes with the undamaged version, sure. Trying to select things like strength or smarts, or designing entirely new traits, not anytime soon.

  61. What price progress? by Art_XIV · · Score: 2

    Now I'm no Scientist (upper S), but "helping" natural selection seems like a pretty dangerous idea.

    How do we know that a "bad" gene isn't a "good" gene under different circumstances? i.e. Sickle-cell anemia offering resistance to malaria.

    I haven't been actively involved in mapping out the Human Genome, but I'm pretty certain that we don't know what all of the genes and combinations mean just yet.

    What if the next few generations carefully weed out genes that cause moles and 300 years from now a mutant Neue Spanish Flu comes along and BAM! the entire human race is gone due to an inability to synthesize protiens that could have only been generated from the now-extinct genes?

    An extreme case, indeed, but you get the picture

    --
    The only thing that we learn from history is that nobody learns anything from history.
  62. Recap, 2nd class citizens. by BrookHarty · · Score: 3, Insightful

    Lets recap some of the big concerns.

    1. Insurance companies not insuring norms. (I hate the term, but it fits)
    2. Low-income families cannot afford screenings, genetic divide.
    3. Normal People replaced in the workforce, 2-3 generations from implementation.
    4. Screenings will filter out "Genius" and "Artists"
    5. Unseen effects after multiple generations of "Altered" humans.
    6. Altered humans breed for specific tasks.
    7. Rights for Altered and Normal humans.
    8. Social interactions between enhanced/altered humans.
    9. Economic benefits for enhanced/altered humans.

    I think if we could have 3 rules/laws, there would be no worries.
    1. DNA Privacy laws.
    2. DNA Discrimination laws.
    3. Free screening and genetic altering.

    Would really be a bitch that my kids cannot get into college, or find work because I could not afford these screenings. They are denied life/health insurance, or any other things we become accustomed to in our daily life. While there are some DAMN good uses for this, this is a very fundamental change to our existance. We need to have basic protections put in place.

    Or maybe, we are all over-reacting?

    -
    Wisdom sets bounds even to knowledge. - Friedrich Nietzsche (1844 - 1900)

  63. Natural Selection by max.inglis · · Score: 1

    Since we've all but eliminated natural selection (do you think people with poor eyesight, mental handicaps or crippling physical defects would get a chance to reproduce 500 years ago?) this is a great idea. We need something in place to eliminate the weak from the gene pool.

    Waaa waaaa I'm sure all the liberals are saying. But that takes away someone's right to reproduce! I think that whomever thinks this is a bad idea has forgotten where we really come from - where weak genes are removed from the mix by natural selection.

    However - I don't think filtering people based on non-threatening characteristics is a good idea. We don't want everyone having to choose from babies #1-50(http://www.scifi.com/twizone/season5.html - Number 12 looks just like you) however we really need to think as society about our genetic future. Even simple things like eyesight are progressing - people with poor eyesight are not at the disadvantage they would have been a few hundred years ago. I'm all for this idea.

    And really, what if we start letting people choose how their kids look? Who cares? People are going to whine that this is going to create another class of people - but I say make it open to anyone who can afford it - it's no different than being able to afford better schools or whatever for your kids.

    Of course, somebody is going to complain that this is discriminatory because of (insert trait that you think makes you a minority here).

    STFU

    max inglis

  64. Why does the cause matter? by Engine · · Score: 1

    Why does it make a difference if homosexuality is genetic or not? That is something I just can't understand. For example, there are theories that it can be genetically beneficial to not get any offspring under some circumstances and rather help rise your nephews.

    I don't believe in that one. But what makes a gene that is against the norm a defect? Extreme intelligens is against the norm. Is that too a defect?

    1. Re:Why does the cause matter? by Reality+Master+101 · · Score: 2

      But what makes a gene that is against the norm a defect? Extreme intelligens is against the norm. Is that too a defect?

      As I pointed out in another post, the question is whether something is functioning in the way it was intended. Note that a defect can be beneficial... for example, if I was born with 4 completely functioning arms, that might be a benefit as a piano player. But it would still be a defect.

      Put it this way. Let's say I was going to have a child, and there was a genetic defect that caused the "switch" of whether to be attracted to the opposite sex to be switched wrong. Let's say there was a simple procedure to fix the problem. Should I do it? I would say, definitely.

      The reason is because the mechanism is not functioning the way it was supposed to. Am I supposed to tell my child that they are doomed to not have children of their own (or at least with great difficulty) because it was politically incorrect to fix that particular genetic defect?

      --
      Sometimes it's best to just let stupid people be stupid.
    2. Re:Why does the cause matter? by balthan · · Score: 1

      But what makes a gene that is against the norm a defect?

      Would you want your children to be homosexual?

    3. Re:Why does the cause matter? by Anonymous Coward · · Score: 0

      what if i was homosexual myself, using one of the sperm donating methods described on other posts?

  65. Umm by redcliffe · · Score: 1

    Steel is actually weaker than the material that makes up our bones.

    1. Re:Umm by mar1no · · Score: 1

      YOU SONOFABITCH I DIDNT KNOW!

      --
      "you sonofabitch i didn't know!"
  66. Damn... Born 30 years too late. by naughtypenguin · · Score: 0

    Hell I wish they would've had this around before I was born.. I could have an 9" penis instead of the damn 18" one I am cursed with now.

    Seriously though, I would do anything to guarantee that my child never has to suffer some illness just because it is in the old gene pool. Ie.. cancer, diabetes.
    Although it would be cool to build an army of super soldiers bent on world domination too.

    --
    Ohhh, your a naughty little birdy...
    1. Re:Damn... Born 30 years too late. by naughtypenguin · · Score: 0

      wooops meant 30 years too early.
      Damn caffiene messing with neurons.

      --
      Ohhh, your a naughty little birdy...
  67. Question to ponder about by tomstdenis · · Score: 1

    How is scientific screening any different then just being picky about who you mate with?

    I think we put too much hype on something that we have been doing for years already.

    I mean how often do you want to actively mate with homely and sick people?

    Tom

    --
    Someday, I'll have a real sig.
  68. mistake? by flez · · Score: 1

    Imagine it's your kid. Imagine your little girl got a form of cancer that could've been screened for.

  69. !weakness by taphu · · Score: 1

    One of the leading theories of human evolution is that we developed our inteligence specifically because of our "weakness" in relation to other species in our environment.

    Evolution is not soley based on elimiation of "bad" genes, it is also based on adaptation and compensation relative to one's environment. For instance, gills on a fish make it live, gills on a giraffe make it.... one messed up giraffe.

    Maybe screening your baby did something good, maybe it prevented some good things. Maybe it did both (good for the baby now, but bad for humanity in 1000 years). Nobody knows, and things that may seem weak now may turn out to be great benifits.

    I don't have much of a problem with messing with peoples gene in and of itself, I just think nature knows how to do it better.

    1. Re:!weakness by NerveGas · · Score: 2

      Evolution is actually based on ability to reproduce. Seriously. When someone talks about "evolutionary fitness", they're talking about how well that animal can pass along it's genes. Brighter colors, a better way to get food, and other positives can enhance that. And negatives like weakness, blindness, etc. can decrease the ability to "get with the ladies".

      The real problem is that there are conditions like Alzheimer's, MS, and others that aren't normally detected (outside of genetic screening) until AFTER the organism has had a good chance to pass on their genes. In a way, they're the "super-defects" - evolution is kind of powerless against them. By the time the chicks figure out that there's something wrong with you, you've already turned out a whole bunch of young 'uns to keep the family legacy alive...

      steve

      --
      Oh, you're not stuck, you're just unable to let go of the onion rings.
    2. Re:!weakness by wurp · · Score: 2

      There should be some slight selection against such traits since the older family member isn't able to help, and in fact can become a burden on, the younger members who still haven't stopped reproducing.

      I suspect that there are some kind of positive effects early in life, even if very mild, that are associated with the same genes that cause the late-in-life diseases.

  70. Re:Recap, 2nd class citizens. by raldanash · · Score: 1

    1. Insurance companies not insuring norms. (I hate the term, but it fits)

    I addressed this in another post-but you might be looking at separate insurance companies in the future. The fact is also, if genetic screening is $$$, the parents already paid a lot of money and it makes some sense their kids would pay a lower premium since costs have been front-loaded.

    2. Low-income families cannot afford screenings, genetic divide.

    Of course there'll be a genetic divide, resources are scarce. Low income families also can't afford good prenatal care-so there's already a life long divide. But the people this might harm the most are those with super good genes, since their advantage over the middle-class normal genes people will be decreased.

    3. Normal People replaced in the workforce, 2-3 generations from implementation.

    Same arguments made about computers and possible AI-but no one is talking about a Butlerian Jihad

    4. Screenings will filter out "Genius" and "Artists"

    Most eggs are wasted anyhow. Though perhaps you have something if some deleterious traits are correlated with genius. On the other hand, some of the greatest artistic periods were during periods of squalor and inequality (Athenian Democracy, the Rennaisance), while the US hasn't produced much more in the past 20 years aside from pop-culture, so does that mean we should go back toward what was in the past??? I mean, if great art is contingent on extreme manic-depressive tedencies, should we make sure there are manic depressives around so we can enjoy their art???

    5. Unseen effects after multiple generations of "Altered" humans.

    This is the same argument eugenicists make about "dysgenics" and "bad breeding." Not saying if you or they are correct, but it's the same argument.

    6. Altered humans breed for specific tasks.

    70% of female PhDs in physics marry other physics PhDs. The fact is that this sort of thing is more and more common.

    7. Rights for Altered and Normal humans.

    8. Social interactions between enhanced/altered humans.

    9. Economic benefits for enhanced/altered humans.

    ???

    --
    NO gods, NO governments, NO [OPTION]....
  71. Sickle-Cell Anemia by the+phantom · · Score: 3, Informative

    Basically, I completely agree with your post, however, there is a slight factual error, namely that Sickle-Cell Anemia is caused by an "unlikely mutation." Let us say that the gene that causes Sickle-Cell Anemia (SCA) is S, and that the lack of that gene is A. Any given person gets one allele (the varient of the gene that causes or does not cause SCA) from each of their parents, with the four following genotypes:
    AA, no expression of SCA
    SS, complete expression of SCA
    AS or SA, partial expression of SCA

    In other words, you do not get full-blown SCA unless you inherit the S allele from both parents. However, if you inherit the S allele from only one parent, then you are affected by SCA to some extent. Generally, there are enough healthy cells in the body to prevent the partial expression from being a problem. In addition, blood cells affected by SCA are virtually immune to Malaria, thus people with a partial expression of the gene are less likely to get Malaria.

    In regions where Malaria is a problem, natural selection favors a parial expression of the gene. Those born without it die of Malaria and those born with the full expression of the gene die of SCA.

    In fact the gene that causes SCA is not that rare, as you state, it is quite common in Malarial regions. There are as many people born in those regions with SCA as not. It is not rare, and is not caused by an "unlikely mutation." SCA is rather uncommon in regions where Malaria is not a problem and there are few breeding people from Malarial regions (i.e. the "Western World"), but (to beat a dead horse) it is quite common in regions where Malaria is also a common problem.

    However, the rest of your comment is right on.

    1. Re:Sickle-Cell Anemia by Thing+1 · · Score: 1
      SS, complete expression of SCA
      ...
      In other words, you do not get full-blown SCA unless you inherit the S allele from both parents.

      So then Senator Hollings' baby will be resistant to malaria?

      --
      I feel fantastic, and I'm still alive.
    2. Re:Sickle-Cell Anemia by the+phantom · · Score: 1

      I don't know, he seems to have quite a few to many alleles (SSSCA!?). I think he should be dead already!

  72. Selfish genes by cpeterso · · Score: 1

    I, for instance, tend to prefer dating women who find fat, bearded computer geeks attractive. That's not an evolutionarily sound move on my part,

    sure it is. Your "selfish genes" want to propagate. They do not care about the evolutionary good of the entire gene population; they just want to help themselves. Your genes know that their/your only chance of reproducing is to date women with like fat, bearded people.

  73. Voluntary Human Extinction Movement by cpeterso · · Score: 1


    She should consider having NO children and helping humanity voluntarily make itself extinct. We have done far too much damage to this planet already.

    Voluntary Human Extinction Movement

    1. Re:Voluntary Human Extinction Movement by Kalabajoui · · Score: 1

      Vehement individuals are a bunch of pessimistic, misanthropic, eco-nuts. Of all the reasons to not have children, the planet is at the bottom of the list for me.

  74. Not the same between weakness general and illness by aepervius · · Score: 1

    From all the post I saw "insightful" in this part of the thread you are comparing weakness (socially, musculatur, and so on) to an illness which are totally different. Most of the weakness you are speaking of, are anyway at the top of the gaussian defining the population. This means that despite yourself or your acquiantance seeing it as a weakness from a biological point of view you are a "normal" person. Now when we are speaking of a biological weakness, those are bad protein mainly, working less effictively or not at all. Example of true "weakness" in genome (which are also illness at an early or late life stage) : Myopathie, The alzeihmer described in the article, many degenerative illness... As for adopting instead of having your own children, why the hell do you think parents try to have recourse (like my sister) to very expensive , painfull, hard to follow fertility treatment and operation ? They could as easily adopt. maybe you are forgetting the psychological aspect and difference between having your "own" children and adopting one ?

    --
    C. Sagan : A demon haunted world:
    http://www.amazon.com/gp/product/0345409469/
    visit randi.org
  75. Breeding for tits and dicks by Anonymous Coward · · Score: 0

    Natural selection is still going strong. Currently it selects for sexual characteristics. Humans today have tits and dicks too large for pre-clothing hunting. Clothing is thought to have been invented 70-50,000 years ago.
    Women still go for jocks, stature, earning power, and intelligence, so these will be pushed too.

    1. Re:Breeding for tits and dicks by Anonymous Coward · · Score: 0

      I'd like to see a little justification of this.

      Was there some kind of National Tit-n-Dick Naked Hunting Study performed? Where are the JPGs?

  76. Speaking as a parent by prisoner-of-enigma · · Score: 3, Informative

    Speaking as a parent who's about to have a baby girl added to our family, I have to ask a very pointed question to those who oppose any sort of genetic "screening". If you have a child, would you not do practically anything on this earth to prevent that child from having to suffer from diabetes, Alzheimer's, or hundreds of other genetically-linked diseases? If you have a child and answer "no", then perhaps you ought to take a good, long look at your child and imagine him/her hooked up to machines, wasting away in a hospital bed. It can happen. It does happen. I hope it never happens to myself, my wife, or any of my children.

    We have it within our power now to take a preventative stance towards genetically transmitted diseases. Undoubtedly this system will be abused, as any system can and is abused, but are not the gains worth it? Early last year I lost both grandparents, both of which suffered long bouts of Alzheimer's. It was horrific to watch as the people who I knew and loved forgot who I was, who they were, and regressed to an infantile state. I would not wish that on my worst enemy. If I can prevent my great grandchildren from one day viewing my children in a similar manner, I'm all for it.

    Are we playing God? That depends on how radical you want to be about this. I firmly believe that we've been given cognitive abilities that have lead to the discovery of genetics. If God didn't want us tinkering with ourselves, why does he allow us to do so? I'd also love for someone to find some good biblical references that say we shouldn't be doing this.

    And, yes, I've seen Gattaca. I know what the consequences of genetic "super babies" might be, but that's just it -- what it MIGHT be. Here's a solution: if you want it, you should be able to have it. If you don't, don't. Your choice. That is what freedom is about, after all? Choice?

    --
    In the end they will lay their freedom at our feet and say to us, Make us your slaves, but feed us. - Fyodor Dostoyevsky
    1. Re:Speaking as a parent by Creedo · · Score: 1

      Speaking as a parent, yes, there are many things I would not do to avoid my children's sufferings. I wouldn't kill them, for one. Suffering does not negate the value of a life. I fully support eliminating genetic disorders. However, I counsel extreme caution. Besides, with the possibility of adoption, you have a choice beyond screening and gene-selection. Have a condition you don't wish to pass to your children? Adopt instead. Cheaper and safer for everyone involved, plus you are helping a child who otherwise might not have a chance. "I know what the consequences of genetic "super babies" might be, but that's just it -- what it MIGHT be." No, IS. People are already applying this philosophy to more than eggs. A French musician couple recently aborted their child due to a completely non- life threatening finger disability, because he could never be a musician like mommy and daddy. His worth as a child was dependent on his physical perfection. "That is what freedom is about, after all? Choice?" Only when coupled self control. Otherwise it devolves into anarchy. "Can do" and "ought to do" are not synonymous. Creedo

      --
      All that is necessary for the triumph of good is that evil men do nothing.
    2. Re:Speaking as a parent by prisoner-of-enigma · · Score: 3, Insightful

      but that's just it -- what it MIGHT be." No, IS. People are already applying this philosophy to more than eggs.

      I'm going to respond by restating my earlier comment: any system can be abused, and any system WILL eventually be abused. That does not make the system a problem, it makes the abuser a problem. Blaming geneticists for the idiocy of the above-mentioned French "mother" would be like blaming Ford because some idiot got drunk and decided to mow down some school children.

      People with ridiculously poor decision making skills DO exist, as do people with highly developed decision making skills. You should not penalize the latter because of the former. While I abhor what was mentioned above, she's done it, it's apparently legal where she lives, and I have no say-so in the matter. Neither do you, other than your opinion which you have stated.

      I won't get into the abortion angle because that wasn't the point of my post. I was not advocating the aborting of babies with genetic "defects", I was advocating the total opposite: using genetic screening to prevent such defects from ever becoming reality in the first place.

      --
      In the end they will lay their freedom at our feet and say to us, Make us your slaves, but feed us. - Fyodor Dostoyevsky
    3. Re:Speaking as a parent by Anonynnous+Coward · · Score: 1
      A French musician couple recently aborted their child due to a completely non- life threatening finger disability, because he could never be a musician like mommy and daddy. His worth as a child was dependent on his physical perfection.

      That is pure evil. When I was younger, I thought the Paul VI was off his rocker with Humanae Vitae and life beginning at conception. Now, as a lapsed Catholic, I'm beginnning to reconsider the idea that Popes may well be infallible when speaking ex cathedra, after all. Look where the slippery slope has taken us already.

    4. Re:Speaking as a parent by Starcub · · Score: 1
      ...If God didn't want us tinkering with ourselves, why does he allow us to do so? I'd also love for someone to find some good biblical references that say we shouldn't be doing this.

      And, yes, I've seen Gattaca. I know what the consequences of genetic "super babies" might be, but that's just it -- what it MIGHT be. Here's a solution: if you want it, you should be able to have it. If you don't, don't. Your choice. That is what freedom is about, after all? Choice?
      God doesn't want us to kill people but he allows that to happen, doesn't mean it's right. We all have a free will that we can excercise in accordance with the manner that Christ taught us, or not. But we all have to live with the consequences of our decisions, and when I say "we" I mean it in a collective sense. Your decision and the decisions of others to screen out particular defects in children they have will have lasting ramifications upon society as a whole due to the absence of life characteristics naturally intended -- and I don't necessarily mean disease. Only in the most serious cases of disease where life would be short, over burdensome, and/or painful could I see justification for genetic screening prior to conception, and I don't think that the case of your grandparents qualifies. We all die of something, and alzheimers may actually be a decent way to go. Where one sees the glass half empty, another sees the glass half full.

      So there is a certain degree of responsibility inherent with the freedom of choice. This responsibility extends not only to the unborn and family, but also to society as a whole. You have to factor God into the equation. If you want a biblical reference, how about the Tower of Babel? If you want something more specific to the issue of genetic screening, you won't find it in the bible. However, the topic has been, and continues to be addressed by the Church.
    5. Re:Speaking as a parent by Creedo · · Score: 1

      Well, this is one convert to Catholicism who would welcome you back with open arms. Creedo

      --
      All that is necessary for the triumph of good is that evil men do nothing.
    6. Re:Speaking as a parent by Anonynnous+Coward · · Score: 1
      Thanks. BTW, I should mention that I had the wrong Pope and encyclical in my post. Paul VI did write Humanae Vitae, but it was about contraception. John XXIII wrote the encyclical I was thinking of, Evangelium Vitae , which said
      But no word has the power to change the reality of things: procured abortion is the deliberate and direct killing, by whatever means it is carried out, of a human being in the initial phase of his or her existence, extending from conception to birth.
    7. Re:Speaking as a parent by prisoner-of-enigma · · Score: 1

      I'm going to respectfully disagree with you here. Yes, responsibility ALWAYS must accompany choice. Where abusers get into trouble is when the have too much of the latter and not enough of the former.

      Yes, we do all die of something, but arguing that is silly. Following your argument we should all avoid medical treatment altogether. After all, isn't that the "natural" way? Now I hope you see the folly of such an argument. If you broke your arm, would you not want a doctor to set it, care for it, in the hopes that you would regain full use of it? Or would you prefer for it to heal "naturally", and end up with a crooked arm and loss of function? I think I know what your answer would be.

      Genetic screening is nothing more than an extension of what we've done before. There is no black and white here, it's a smooth shade of grey. I will state again: no doubt the system will be abused. But that is not a reason to "outlaw" or ban the idea. Following THAT reasoning, we should abandon pianos, because someone might just drop one on me one day. ANYTHING can be abused. You don't outlaw the process, you instead educate, cajole, and influence the abuser until they either (a) stop abusing it or (b) become a niche minority that you simply must accept. No process is perfect. To assume otherwise is stupid.

      Using the Tower of Babel to support your argument is not a very good analogy. The builders of the tower wanted to elevate themselves above God. That is not the goal of genetic screening, anymore than innoculating against smallpox is taking away from God. We have had an ability to improve ourselves through genetic selection since the beginning of the race by choosing our mate. Now we have developed that SAME ability to a much more precise point. We've become more efficient, if you will. I fail to see how that profoundly changes the theological question, or that it presents any moral problems whatsoever to those who would use it responsibly. As for those who would NOT, that is between them and God, and they'll be judged for it by far higher and greater powers than you and I.

      --
      In the end they will lay their freedom at our feet and say to us, Make us your slaves, but feed us. - Fyodor Dostoyevsky
    8. Re:Speaking as a parent by Starcub · · Score: 1
      ...Yes, responsibility ALWAYS must accompany choice. Where abusers get into trouble is when the have too much of the latter and not enough of the former.
      Certainly, I agree.

      ...Following your argument we should all avoid medical treatment altogether. After all, isn't that the "natural" way? Now I hope you see the folly of such an argument.
      Let me explain further: When I talk of things naturally intended, I don't mean to imply that medicine should not be practiced. I think history teaches us that there is much good to be gained from the responsible practice of medicine. Medicine and genetic screening and/or modification are completely different in the sense that treating diseases rarely has an adverse impact on the individual or society as a whole. There is a big difference between setting a broken arm and choosing to exclude the possibility of alzheimers through genetic screening.

      The fact of the matter is that we are only able to identify a very small number of markers for a very small subset of human conditions. We just don't know what the impacts of even selective screening will be upon both the individual and society as a whole. Consider that by choosing to screen out the possibility of alzheimers, we unintentionally end up screening out other positive traits that would be beneficial both to the individual and for society as a whole. Beyond this, who is to say that the one to be born with any specific affliction will not be able to overcome or even be driven by their affliction to do great things, to enjoy life more fully? Where one sees a glass half empty, another sees the same glass half full.

      You don't outlaw the process, you instead educate, cajole, and influence the abuser until they either (a) stop abusing it or (b) become a niche minority that you simply must accept.
      Well, there are some abuses that simply should not be tolerated at all because of the direness of the consequences. We need to identify these classes of abuse and do everything we can to prevent and discourage them. For the moment, I think it best to err on the side of conservancy when dealing with science as powerful and consequential as genetics. Remember, I never said we should outlaw the practice of pre-conception screening all together, but its application should be extremely limited. I think the best mid to long term solutions will result from serious debates on the subject by religious, scientific, and governmental bodies.

      ...The builders of the tower wanted to elevate themselves above God. That is not the goal of genetic screening... ...We have had an ability to improve ourselves through genetic selection since the beginning of the race by choosing our mate. Now we have developed that SAME ability to a much more precise point.
      I hope you understand now where I am coming from. There are a couple of analogies in the story that I believe are relevant to our discussion. Reaching the top of the tower symbolizes the natural desire of mankind to wish to be like God. However, there is great folly in this idea in the first place because it's reasonable to assume that man could not exist at the top of such a high tower anyway. Assuming God could be grasped from the stars, we would run out of atmosphere trying. The analogy being that our own wisdom and capability for understanding is limited. We may think that we can identify a particular gene that causes this or that, but we may never be able to accurately model human development to the point of knowing how to accurately modify much less create. We know of genes and proteins, and perhaps more, but how do they all interact to create, grow and sustain life? We have a hard enough time with our weather which is just one aspect of our environment, and I'm willing to bet that the human body is just as complex a system as our environment, if not more so. Another analogy; God destroyed the tower to prevent the people from doing something fruitless and potentially harmful. The degree of His power was manifest in those involved in the construction and reveals how effective God can be. This gives believers confidence that God will rescue His people from the folly of poor decisions. So if I am right I shouldn't worry too much because I know that God will not long tolerate the practice of eugenics. If I am wrong, then I don't have to worry about it.

      Why then should I be concerned about weather I am right or wrong? Well, free will gives us the option of screwing up, and going against God's plan for us is sin, and sin always has negative consequence. How do I know if I am right or wrong? I pray on the matter and ask for wisdom. I also review the Church's positions since there should be no other body more reliable for representing God's will for us than the Church, and I believe history proves this to be true. Debate on this topic is critical now because the pace of scientific developments geared towards effecting change in our genetic makeup is rapidly outpacing our ability to comprehend the ramifications. Eugenics is a relatively new topic in the Church and I strongly suggest you read up on some of the Church's positions and relevant Papal encyclicals (be aware that this is challenging reading). Someone else in this thread posted the link to Evangelium Vitae, here is another you may find informative.
    9. Re:Speaking as a parent by prisoner-of-enigma · · Score: 1

      I hope you will understand when I say that although I am Christian, I am not Catholic, and I do have a number of issues with the Catholic Church in general -- most of them having to do with Church policy (edicts) have a great deal of intertwining with political policy. But I shant get into that with you. You have just as much right your beliefs as I do, and I shall not criticize you or the Church because of that.

      Your arguments are well thought out, and perhaps our opinions aren't so far apart here. Where we seem to part ways is that you wish to err on the side of conservancy due to the possible "dire consequences". I, on the other had, believe that any system put in place with be both (a) abused and (b) improved over time. No process is static. I firmly believe that while there are possibilities of abuse, the potential good far, far outweighs them, especially since I believe abusers will be villified to the four corners of the earth (not to mention the incredible legal fodder herein). I have more faith that human nature, while quite flawed, generally works out in the end.

      --
      In the end they will lay their freedom at our feet and say to us, Make us your slaves, but feed us. - Fyodor Dostoyevsky
    10. Re:Speaking as a parent by Starcub · · Score: 1
      ...I do have a number of issues with the Catholic Church in general -- most of them having to do with Church policy (edicts) have a great deal of intertwining with political policy.
      Fair enough, I occasionally question Church policy myself. For example, I did not always agree that abortion and pornography were evil. While I had little trouble understanding the evil of partial birth abortion, my thoughts were centered on a highly scientific analysis of the point in development where a fetus actually acquired the ability to feel pain. Unfortunately, I realize now, that although this question is in itself logical, it is also extremely limited. It neglects consideration of the potential psychological impact on the mother, and possibly on people involved in the procedure (which I've learned all too often is devastating). In addition, the tolerance of abortion has the effect of desensitizing us to the value of life. Where do we draw the line? I have learned of deceptive practices by abortion providers who are generally driven by the profit motive at the expense of the patient -- and from what I can tell, this describes most of those in the industry. As for pornography, while I may have thought it pleasurable and seemingly innocuous, it tends to promote negative behavior in it's patrons, negative consequences for it's participants, a devaluation of the appreciation and necessity for traditional opposite sex relationships, and leads people further into other forms of more destructive behavior. So my point is that while I may initially disagree with the Church on a particular subject, it has been my experience that this usually is the result of my taking a position based on thought centered on my own knowledge at the time. I have discovered that when I make an effort to really evaluate my positions WRT church teaching and attempt to justify the opposing viewpoint, I expose myself more deeply to the experience of others and the logic of their experiences taking into account a world view which is radically different from the one I grew into. Often times this leads me to conclude that I was wrong to begin with.

      There are still some positions the Church holds that I'm not sure I'm willing to accept and I suspect that as time goes on there will be more. For example, and this may seem radical, I don't believe that one can ever justify the taking of life for any reason. This belief I hold based upon my own experience with God and His capability to correct personal error -- even for one whose heart is like stone. My own fallibility in being able to accurately analyze a situation plays into this belief as well. I will admit though, that to accept my position requires a certain degree of faith even for me, and certainly much more for one who has not experienced God personally. Given that, I may yet find myself in error on the issue.

      Where we seem to part ways is that you wish to err on the side of conservancy due to the possible "dire consequences". I, on the other had, believe that any system put in place with be both (a) abused and (b) improved over time. No process is static. I firmly believe that while there are possibilities of abuse, the potential good far, far outweighs them....
      Yes, you hit on one key aspect of our disagreement: The differences which arises from approaching the problem of benefit vs. loss from different perspectives. We each bring our own personal knowledge and experience into the analysis of weighting factors. However, I want to stress that in addition to potential benefit vs. consequence is the consideration of our ability to correct and contain any harmful consequence. Let me give you a more concrete example that you might find more useful in understanding my opinion. Take the case of genetically engineered corn. Monsanto, a pharmaceutical company in St Louis, has engineered a variety of corn designed to produce a natural pesticide called Bt toxin to protect against various corn eating insects. However, it has been observed that the pollen produced by Bt corn has the unintended side effect of killing Monarch butterfly catapillars. In addition, the corn itself seems to reduce the lifespan and reproductive ability of lacewings and aphids (and incidentally, this seems to me like it may be divine consequence designed to protect us unwise activity). The aphids feed directly on the corn, and the lacewings feed on insects that feed on the corn that serves to counter the original design of the corn! These are only consequences that we can observe. Who knows what effects may occur that we'll only be able to observe later on. Perhaps damage to the soil, or other creatures in the ecosystem that eat these insects. How far into the chain will the consequences be felt? How will we be able to reverse the effects once begun?

      Here we are talking about a simple modification to a specific form of plant life. And if you read the links, you probably know how much faith I place in the ability industry to regulate itself, or of human nature to respond to abuse. Being able to respond to this abuse requires first that we know it is taking place. Only then can we marshal against it, which may be difficult depending on the sociopolitical landscape and the nature and prevalence of the abuse. Did you know this corn is being used in this country as I write this? Can you imagine the development of a black market for pristine food sources we once took for granted? My goodness, I shudder to think of what might happen if we start playing with the human genome. This is one reason why I feel strongly that politicians need to get moving on the issue of genetic engineering *now*.

      I have more faith that human nature, while quite flawed, generally works out in the end.
      I too believe that things will work out in "the end". However, I don't think it will be human nature that saves us.
  77. Screening Genes. by Anonymous Coward · · Score: 0

    I have no problem as long as they screen for ignorance and stupidity :)

  78. Some has to beow^W say it.. by scorcherer · · Score: 2

    All your base pair are belong to us!

    --

    --
    The Cap is nigh. Time to get a fresh new account.

  79. Playing God? by clary · · Score: 4, Insightful


    The problem with this assumption is that you don't know what other things you're screening out when you screen out the disease. A somewhat contrived example of this is Stephen Hawking. Of course no really knows the cause of ALS, but suppose it turns out to be genetic. Stephen Hawking would have been screened out of existance, and consequently all of his contributions to science.

    IMHO, by doing this kind of thing, we pretend that we are God and that we can forsee every possible future. In my opinion, this is foolishness. We are too focused on our inconveniences, and spend too much effort in the avoidance of struggle. We almost universally fail to see the good that can come out of those struggles.


    This is no more playing God than deciding whether to have a child or not in the first place. If Hawking's parents had not had children, then he would not have contributed to science. All our choices have consequences we cannot foresee, not just the ones that use fancy new science. Get over it, and try to make the best, most ethical choices you can.

    That said, there may be other good arguments against gene screening. But this one just doesn't hold water.
    --

    "Rub her feet." -- L.L.

    1. Re:Playing God? by markmoss · · Score: 2

      And if Hawkings' parents had known they were carrying the genes for ALS, they might well have decided not to have children in the first place. This depends on what the odds actually are, though. ALS is probably not a single-gene defect, or it would have been found already, and if I was told that I and my wife had all 10 genes needed for something like ALS but the chances of them coming together in one child was 1 in 1024, I think we'd risk it, because there's a far higher chance of something else going wrong anyhow... And I'm sure that whatever genetics and environmental combination gave Hawkins his genius is far more more improbable than that.

      But in this particular case, there was definitely a 50-50 chance of the child losing his or her mind before 40. It would be cruel and irresponsible to have a child unless better odds were possible.

      As for adoption, there aren't that many healthy, normal babies out there, and I'd think that the fact that the mother was not going to become unable to care for the child long before it was an adult would be a pretty good reason not to give one of them to this family.

  80. Why is Natural Selection so Great by solman · · Score: 1

    There are alot of posts here supporting Natural Selection with an almost religious zeal (some irony in that). What is so great about natural selection? OK, so its been the dominant form of evolution on earth for a few Billion years. Things change. Its ironic that people are arguing that Natural Selection needs PROTECTION from science.

    The whole idea behind natural selection is to let biological organisms compete to determine which is best suited to survive. If Natural Selection is so great then the organisms that it produces should have better long term chances of survival than those produced by Scientific Determinism. If not, then by its own principles Natural Selection should face extinction.

  81. Beyond this Horizon by markmoss · · Score: 3, Insightful

    A very long time ago, Robert A Heinlein wrote a book, Beyond this Horizon, where superior babies were produced by screening the entire parental genomes to pick out the best combinations. It's like this, on a much larger scale. No genetic modifications, no splicing in foreign genes, just picking out the best eggs and sperm. That's a whole lot less likely to cause unintended consequences than tossing in new genes, and if the genome was well enough understood, it should be good enough to nearly eliminate double-digit IQ's, chronically ill, and the genetically criminal within a couple of generations.

    There were "control naturals", people whose ancestors had never used this genetic filtering. They received a governmental stipend to compensate for their disadvantage. Heinlein never really discussed _why_ they existed, perhaps he thought it was too obvious. Sometimes those genes you would normally filter out might turn out to be strongly advantageous in different circumstances -- heterozygotes for sickle cell anemia are virtually immune to malaria, for instance.

    Finally, note that this book is the most utopian of all Heinlein's work, and the most boring. A perfect society is one where "interesting" things don't happen to people, so getting a story out of an almost perfect society is difficult... 8-)

    1. Re:Beyond this Horizon by praksys · · Score: 2, Insightful

      If I remember the story rightly I think Heinlien did give an explanation of why "naturals" remained (and were even subsidized by the state). He thought the natural population was needed to preserve the possibility of new beneficial mutations arising.

      If all you do is select for genes that you know to be good, and you never deliberately add new genes (i.e. no engineering or splicing), then the chances of new beneficial genes entering the gene pool seem pretty slim.

    2. Re:Beyond this Horizon by naasking · · Score: 1

      it should be good enough to nearly eliminate double-digit IQ's...

      You will never eliminate double-digit IQ's. IQ by definition is a statistical measure of relative intelligence (your intelligence relative to the average). If you eliminate current double-digit IQ's, then the average shifts up until to mean is 100 again.

    3. Re:Beyond this Horizon by markmoss · · Score: 2

      No -- IQ = 100 is supposed to be the average of the American population as of the date the first IQ test was invented. The average has been slowly climbing ever since then. IIRC, it's around 110 now. Through the 1950's, this rise was assumed to be due to the reduced occurrence of intelligence-stunting events such as malnutrition and certain infections. This explanation doesn't work anymore; I don't know whether the attempts to make the test culturally neutral have also led to a little dumbing down, or whether increased stimulation of sorts in early childhood (TV, pre-school, toys actually designed as IQ test practice) has led to an increase in whatever the test measures. (It certainly doesn't seem to correlate with being smart in practical matters, like figuring when a stock is overhyped or a politician is bullshitting.)

  82. Dogs vs. People by Knunov · · Score: 1

    Dog breeders have never been able to tinker with the genetic code, though they likely soon will.

    If you wanted a dog to have spots, for example, you chose two dogs that had the size/color/pattern of spots you were looking for and bred them. Poor eyesight or hip problems came later. You got the bad with the good.

    Now they might be able to get healthy dogs that look exactly as they wish. Best of both worlds.

    Knunov

    --
    Why do users with IDs under 100,000 or over 700,000 usually have the most worthwhile comments?
  83. Intended by whom? by Engine · · Score: 1

    When you say that something is intended you imply that it is intended by someone. Who is that?

    You cannot mean god. I am sure that every child that is born is according to his will and he equips them as he likes.

    Genes don't intend anything at all, even if you can get that impression from some popular scientific litterature. If it never arised anything new there would be no evolution.

    Like the four arms. If it really was beneficial it would be an evolutionary advantage and from the genes point of view it would be something good. (I know that I in some way make the same mistake mentioned above when I talk about the genes point of view, it's just so practical to express it that way).

    Maybe in 30 years it will be very popular to be homosexual. They might hate you for fixing them.

    1. Re:Intended by whom? by Reality+Master+101 · · Score: 1

      When you say that something is intended you imply that it is intended by someone. Who is that?

      "Intended" doesn't have to mean by someone. I simply mean the natural function. For example, chlorophyll is "intended" to provide food to a plant. That doesn't necessarily mean that there has to be a someone providing intent.

      Maybe in 30 years it will be very popular to be homosexual. They might hate you for fixing them.

      If it's in vogue (hey, it's never happened in the history of mankind, but you never know), nothing is stopping them from making the switch.

      --
      Sometimes it's best to just let stupid people be stupid.
    2. Re:Intended by whom? by SIGFPE · · Score: 2

      Genes don't intend anything at all

      They do metaphorically. When discussing evolution the intentionality metaphor is a pretty powerful one and making deductions via the use of such a metaphor often gets you the same results as making a literal argument except in the former case it's easier to think about because humans seem to be particularly good at making arguments about intentions.
      --
      -- SIGFPE
    3. Re:Intended by whom? by Anonymous Coward · · Score: 0

      Actually it was very much in vogue in ancient greece. The "perfect" relationship was between an older man and a younger boy. Eat that

  84. My name is Bob... and I'm a dandrahaulic. by Decimal · · Score: 2

    Even that noble goal is a slippery slope to tread. What diseases do we screen for? Cancer? Diabetes? Sickle Cell? ADD? Psoriosis? Dandruff? Halitosis?

    Dandrif? Nonsense. There's no way you could possibly screen out dandruff! Dandrif is a disease against which we are powerless. It is only when we put our faith in a power greater than ourselves, such as Head and Shoulders, that we have the strength to overcome it. Yes my friends, there is hope. But you will not find it through such worldly means.

    --

    Remember "Bring 'em on"? *sigh
  85. Bad Troll.. Go sit in the corner! by jabber · · Score: 2
    What happens when the governments start screening every child that is born for any inherent form of "weakness"? Will those children never receive the chance to live?

    Right.. What's next?? Women, mandated by law to get pregnant each time they ovulate, so as to not deprive that egg of it's chance at life?? What a cruel fate for a potential child, so be soaked up by a tampon... How inhuman!!

    Or better yet, picture this: Late evening, quiet suburban neighborhood.. Suddenly a SWAT team bursts through a second story bedroom window, laser targetting dots panning around the room.. A voice booms outside: "EM Emalb!! Put the sock down son!! Step away from the semen, and for God's sake, don't wipe your hands!! That's a potential human you've got there!!"

    Depriving unfertilized eggs of the chance for life?? Get real!!

    --

    -- What you do today will cost you a day of your life.
  86. Designing what? by cassandy · · Score: 1

    One thing a lot of /.ers seem to overlook here is the fact that they weren't 'screening embryos for Alzheimer's'. Designing a baby means taking a bunch of fertilized embryos, finding one that suits your wants/needs, and killing the rest. It's the equivalent to getting pregnant just so you can have an abortion.

    Some people are saying that hey, if they want to, why not? Hey, lets create a bunch of almost-humans, find the one in 100 that has the red-hair trait and kill the other 99.

    I think a lot of people should have a problem with this

    --
    Have you thought about what you're looking at today?
  87. AWESOME! by Anonymous Coward · · Score: 0

    I don't care what anyone else says, this is bitchen. Healthy babies rule!

  88. Alzheimers gene treatment by ehiris · · Score: 1

    Hopefully they won't stop researching into treating early Alzheimers at this point.

    It's amazing but how could this be tested in in men? There's a lot of swimmers to select from.

  89. I'll say it again like I said it before by Julian+Morrison · · Score: 1

    ...if you aren't "playing god", you aren't yet fully human.

    What is a human? A human is a rational ape. A human who choses to demphasize their rationality and live like an ape, are they a human? Barely if at all. But a human who stretches what they are into what they could be by means of the science that is rooted in disciplned, non-self-decieving thought, they acheve the pinnacle of humanity precisely when they gain the power to move by rational choice and deliberate action beyond the old form of what was human.

    Thus do I welcome all advances in the science of germline eugenic creation of post-humans.

  90. Fuckwits? by Knunov · · Score: 1

    "...fuckwit genetic engineers..."

    I would wager there are no "fuckwit genetic engineers". In fact, I'll bet they are quite intelligent. More so than you or me.

    Knunov

    --
    Why do users with IDs under 100,000 or over 700,000 usually have the most worthwhile comments?
  91. Re:Recap, 2nd class citizens. by Alpha+State · · Score: 2

    Don't forget backlash - imagine paying megabucks for your perfect child only to have them hated and feared because they're different, or an abomination against god. Imagine children screened for disease suffering the same fate because of people abusing the technology.

    And no, we are not over-reacting. Are there any big advances that haven't had negative side effects which weren't predicted? Even penicillin (the most beneficial advance I can think of) has been responsible for the evolution of super-bacteria and allergies in humans.

  92. Bigger, Better, Stronger, Faster is Good by Knorin · · Score: 1

    Obviously, screening for genetic diseases is good. Healthy people are, all other things being equal, better than unhealthy people. The "Steven Hawking" argument holds no water because there is not nor ever will be a screening test for who will make brilliant scientific discoveries. It could be the runt of the fallopian tubes but it could just as easily be the favored cell. Moreover, screening for other characteristics, wereit possible, would also be good. Remember, a person is not their body. The body is nothing more than a machine they use to interact with the world. The person inside the body's existence is largely determined by upbringing, social interactions, memories, education, creatvity (as opposed to intelligence), environment and the choices they make of their ow free will. None of the things that really define a person can be screened for because they are determined after birth. Might as well give the person a better machine to pilot. Genetic diversity will still exist because designer babies will only be available to those well off financially. For most of the world, it won't even be an issue. Even in this country, there will be both people who refuse to have any part of it due to their beliefs and people who have children the old fashioned way because they like to have sex. If a plague comes around, there will be plenty of genetically-accidental humans around that if there is an immunity gene then mankind will survive. There's even a good chance that designer babies would be no more than a fad that passes when the first generation of supermen matures and find that it has not solved all their problems. Playing God is also not an issue here because if God had not wanted us to become mechanics he would never have given us the opposable thumbs to pick up tools.

  93. Michael Jordan by Galvatron · · Score: 2

    The only comment I want to make on this is that Michael Jordan didn't start playing basketball until high school. No doubt, he did other athletics prior to that, but obviously nature vs. nuture is a sticky argument indeed.

    --
    "The question of whether a computer can think is no more interesting than that of whether a submarine can swim" -EWD
  94. Engineering Addicitions by Anonymous Coward · · Score: 0

    Let's talk about engineering addictions, like alcoholism. Alcoholism and other addictions are obsessive traits. Being a workoholic is very similar to being an alcoholic, except that it is socially acceptable. How many of the great advances in science and medicene were the result of some divine intervention, of the proverbal light-bulb idea? And how many were the result of grueling days, weeks and years of hard work? What I'm saying is that many of the great advances in science and medicene were the products of people who were genetically predisposed to obsessive personalities. Many of our great works of literature were written or composed by people who have obsessive personalities. Stephen King, Edgar Allen Poe and Ernest Hemingway are examples of this. There are personality traits that can lead a person either to greatness or to absolutely crash and burn in adulthood. Engineering these traits out is not necessarily a good thing.

  95. More potential profit for these companies... by EvilBuu · · Score: 1

    ...if they are also in the buisness of pharmaceuticals. Imagine bringing your flawless-chromosome baby into the world, courtesy of Progeny-Corp, only to learn thay they have contracted a normally-rare disease once they hit adolescence. Is there a cure?

    Sure, but Progeny-Corp is the only company that sells it. Sure, such a thing would be horribly unethical, but that has never stopped big pharmaceutical companies before.

    --

    Green-voting, republican-registered, socialist-libertarian.
  96. Gee thats fucking original... by Anonymous Coward · · Score: 0

    Gee thats fucking original...

  97. "Special" kids by Anonymous Coward · · Score: 0

    That make it so all the people that are "special" enough here to hate windows can be made to have the ability to suck on thar own cock?

  98. Glad to see it. by AnotherBlackHat · · Score: 2

    It sure is nice to think of all those people who would never have been selected as mates simply because one of their chromosomes caused a physical abnormality that will now be given a chance.

    Before you condemn the practice, consider that it's only a matter of degree between this and deciding whom to marry. Unless you think people should be paired at random, you've already decided there's an amount of this that is acceptable. The only questions are, do we draw the line, and who gets to decide where we draw it?

    -- I come from a very long line of families with children.

  99. Something is wrong here. by Starcub · · Score: 1

    The Article in the Washington Post states that eggs were screened. However, the JAMA article says that it was embryos. Hmm, any takers on which source is more reliable? There is a huge difference.

    I can't help but think that PGD is just bad science. Is PGD by definition, embryonic screening? Even if we could screen eggs alone, is the process itself safe for the subject egg were to be chosen for fertilization? What about the sociological impact of selective conception? It seems to me that scientists in general are disconnected from the moral implications of the work that they do. Perhaps this is a result of the amount of time and effort required to understand extremely complex systems. The resulting affect being to strengthen ones own opinions on a matter at the exclusion of others. Little time is there for consideration of factors that are unrealized, or perhaps even unknowable within the limitations of human comprehension. This is why it's extremely important to involve others in the debate -- religious and societal sources having no small part. Unfortunately when this fails, we all have to live with the consequences, some of which can be catastrophic.

    It's all too easy and simplistic to say "If we change this gene, we can prevent such and such from happening" or "We can live without this particular human characteristic or disease". But the fact of the matter is that even if we could say this with some degree of certainty, there remain unanswered questions on the implications of doing so. Even if we were just screening eggs, the consequences could have grave sociological impacts. In the case mentioned, we might unintentionally end up creating sociological imbalance in personality, physique, sex, intellect, temperament, etc...

    One might well argue that the sociological impact arising from pre-conception screening would be small if such screens resulted in the prevention of a very small number of very serious diseases. Perhaps this would be valid, and something we as a society could handle given the potential benefit for the pre-conceived. However, what concerns me is that such screening could be abused, especially in the highly insular medical and scientific bodies of today. I think we need some serious analysis, debate, and importantly, legislation on this issues like this ASAP to prevent abuses from taking place.

  100. Future Nightmare Litigation by marko123 · · Score: 1

    Imagine insisting on having a "pure" unscreened child, and then the child sues you for their genetically inherited cancer.

    --
    http://pcblues.com - Digits and Wood
  101. it will get cured anyway by Anonymous Coward · · Score: 0

    By the time the kids are 40 , stem cell technology or genetic engenering or some other technology will have cured alzheimer anyway . That is if not technofobes and ludities , like a few of the people posting here , or some other leftovers from the spanich inqisition come in to power .

    ...oh wait , i forgot ashcroft and buch alredy are in power .

  102. 160 people is all that is needed by hyperionfarmer · · Score: 1

    There was a story just the other day here about a healthy "multi-generational space travel" needing only 160 people. Do you really think that that genetic diversity is going to be threatened by a few billion people designing babies??

    I also find it funny that people who use evolution as a reason NOT to have "designer" babies. News flash: Evolution doesn't go away just because we have brains, it just changes. If human's "over-design" themselves, nature will take care of it's own. We are and always will be part of nature.

  103. Rich = Perfect, Poor = flawed by zipgunII · · Score: 1

    Has anyone wondered how much this procedure costs? Who paid for it? Will this child's health insurance be cheaper by virtue of the fact that there is a "guarantee" that they will not develop alzheimers? It this becomes widespread we might be seeing:

    --Rich potential parents paying for screening, and getting better heathinsurance rates for thier children.

    --Poor parents giving birth to high risk children, who can't be insured, or couldn't afford health insurance because of the increased premiums.

    --Research into curing these illnesses being neglected or forgotten, since all of the patients that could pay for treatment will have been born without the gene that causes the disease. The disease being "erradicated" from the population that "matters"

    --Lastly, by filtering out genes from the gene pool,we run nthe risk of elimiating the flexibility of the species to adapt to changing environmental conditions. Remember, the gene that causes sicle cell anemia, also provides some protection against malaria. If only the beautiful people are born, the wealth of "ugly" genes will be lost, and mankind's destruction will be only one disease or environmental change away.

    Besides, isn't it more fun to make the baby the old way? ;)

  104. Easy solution: by The+Step+Child · · Score: 1

    Socialist health care

  105. Yup, and... by The+Step+Child · · Score: 1

    ...sickle cell anemia. In some parts of the world - I don't remember why exactly - sickle cell anemia is actually a genetic advantage...hence selection against people without that trait, and eventually a high distribution of people who have it.

  106. I'm Not sure about this one.. by pennsol · · Score: 1

    IIRC this is in the same ballpark as what the Nazi party did with the Hitler youth.. i.e. blond hair blue eyes only kind of thing.. maybe not to the extreemes but it's a start.. where is the end? I personally have problems i'd like to have been born without i.e. athsma, alergies, baldness at a young age but they are the things that make me ..well me. I've never been against abortion and there may be things that this world could do without. things that are truly life threatening to the child but if you think your child will have Alzheimer's i think you should just not have a child. and as far as abortion goes..think before you act is the best policy.(read:birth control)

    --

    Just Limin' Mon

  107. The genetic superclass of the wealthy ... by Anonymous Coward · · Score: 0

    Human beings get a lot of their character and their life paths from their environment, not their genetics. It starts with the infantile environment that they are raised in.

    How do you think the wealthy raise their kids? I'll bet that they don't plunk them down in front of a TV set nearly as often as the poor fuckers on the other side of the tracks.

    So we've already got generational transfer of characteristics. Buffy learns to relate to authority in a completely different way than Lawanda. Buffy learns different attitudes about school, and so on. Who's more likely to have a lot of power and money when they are 35? And do you think that Lawanda gets the shaft because she's genetically inferior, or do you think that Lawanda would do just as well as Buffy if they got switched at birth?

    Is it nature or nurture? I think for humans operating in a human society, it's about 10% nature, 30% nurture, and 60% the choices that you make yourself.

  108. Gattaca! Damn, I don't want to be a janitor! by Sorcerer13 · · Score: 1

    Well, I guess it could be worse, I could be working at McDonald's. Wait, I've done that before, and I was responsible for mopping the floors and stuff too. Doh!

    1. Re:Gattaca! Damn, I don't want to be a janitor! by Anonymous Coward · · Score: 0

      I did that mopping in McDonald's,now
      i am coding for 130k per year.

  109. OT - Your sig by Dyolf+Knip · · Score: 1, Offtopic

    Where was that said in Fight Club? It doesn't ring a bell. A deleted scene, maybe?

    --
    Dyolf Knip
    1. Re:OT - Your sig by FarHat · · Score: 1

      Its there in the book. Very last page.

      FarHat

      --
      At the intersection of computation and biology.
  110. Nature vs. Nurture is not a closed argument by Bonker · · Score: 2

    It is a sticky subject... and one not many of the posters here seem to gather.

    Most human traits are defined by a combination of the two. This is evident in the 'athletic build but lazy' scenario I laid out. My father is a guard at a government facility. He works out ever day in order to stay in terrorist-proof shape for his job. He is lean, mean, and at nearly 50, could beat most comers in a street brawl.

    I have the exact same build as my father, but I've always been significantly more sedentary, preferring to write, make art... other sit-down stuff. I try to watch my diet but probably eat more fat and cholesterol than I should. I could still use to lose a few pounds.

    We have very similiar builds, my father and I, but he has done strenuous work since he was a child whereas I have not. If I were to work damn hard for the next two and a half decades, I *might* be able to approach the kind of shape he is in at 50, but never quite make the same levels he does.

    The argument for mental tasks is a little more clear cut. It's been evidenced by data collected in a few of the more famous child abuse cases that children who are isolate, not exposed to language at all (spoken or sign), slowly lose the ability to use language until about age 14 when they will probably never speak (or sign) coherently. They lose the ability to develop many higher reasoning skills at the same time. Even if a person has an affinity for language, if their brain is put in a vacuum like this, nature determines the outcome.

    The most famous case of this kind of depravtion is the 'Genie' story. In 1970 young girl of about 13 was found chained to a toilet in her grandparent's back room. She had had little or no experience with anything other than that room her entire life. (Outraged? If I remember correctly, the grandparents were sent away for a very long time) Despite the fact that her family had *no* history of mental illness or retardation, Genie displayed all the symptoms of either severe mental retardation, autism, or brain damage simply because her brain had nothing to develop against like any kid who hadn't suffered that kind of abuse.

    Amoung her other problems, Genie couldn't... and still can't... speak coherently despite intensive tutoring and help. She lost that ability due to the poor environment.

    Nature does have a siginificant role to play in determining our traits. The world around us affects us in so many myriad ways that it should not be discounted as so many of the posters replying to this have stated.

    --
    The next Slashdot story will be ready soon, but subscribers can beat the rush and slashdot the links early!
    1. Re:Nature vs. Nurture is not a closed argument by Dyolf+Knip · · Score: 2

      I was rather appalled at the story of Genie and looked it up. She was kept either chained to the toilet or suited up in a strait jacket-sleeping back for nearly 13 years, beaten whenever she spoke, all based on her father's assessment when she was 11 months old that she was retarded. Mom was crippled and beaten often, Dad killed himself shortly after Genie was discovered. He left a note saying "The world will never understand." Probably the only thing he actually got right.

      --
      Dyolf Knip
  111. Real facts about sexuality... by Brendan+Byrd · · Score: 2

    Here. Read and be enlightened.

  112. OT: Your .sig by the+phantom · · Score: 1

    I am glad to note that someone else notice the appearance of Agent Elrond:

    Mister Baggins... you lead two lives. In one, you are Frodo Baggins, an unassuming little hobbit. In the other, you are the Ringbearer. One of these lives has no future...

  113. Most things are a little bad and a little good by olman · · Score: 1

    I really do not respect black-and-white worldview.

    For example, without going into whether homosexuality is evil at all.. It can be good for the community from evolutionary point of view. You have non-childbearing healthy women and non-fathering healthy men who are *not* using majority of their energy and time for raising children.. That energy is probably going somewhere else, don't you think?

    In any case, as other poster already noted, there are far more bisexuals than there are homosexuals. Majority of bisexuals just happen to develop either hetero- or homosexual identity so they appear either straight or bent socially.

    For my closing line, I'm going to have another evolutionary argument. If homo- and bisexuality was bad for the survival of species, any species, it would've been evolved out of existence millions of years ago. Instead it's almost universal and more common than any single hereditary disease.

    It may be bad for the invidual genes which will not propagate, but it might very well be good for all the others.

  114. Take what you get by Timothy+Healy · · Score: 1

    Perhaps we need to take what nature gives us. Often a lot of satisfaction comes from some of the things we often view as negative. Dark very often helps us appreciate light. I think trying to eliminate every possible negativity, every inconvenience, discomfort, and so on only contributes towards the modern trend of taking more and more simple things for granted, especially good health.

  115. I thought this was wierd by Anonymous Coward · · Score: 0

    The first thing I thought when I saw this was that it was referring to beany babies and cabbage patch dolls. The original designer babies!

  116. Government Funded by AviN · · Score: 1

    I think the government should offer to do this to people for free. This way rich people wont end up with a huge evolutionary advantage over poor people, something that would make it even more difficult for the poor people to become rich.

  117. Just wondering... by gdyas · · Score: 2

    Why is it, on Slashdot, that when I get moderated as both insightful AND flamebait, that flamebait is what get's shown next to the post?

    --

    The only tool you've got against psychosis is experience.

  118. An analogy: dog breeding by phlurg · · Score: 1

    There seems to be an implicit assumption in several posts that if you could in fact choose, say, your childs hair/eye color, that everyone would tend towards some sort of blond/blue-eyed homogeneity. But consider the world of purebred dog shows. There are several hundred dog breeds, and people seem to love a huge variety of beasts. I have a Boston Terrier with bulgy wonky eyes that several of my friends have called the ugliest dog in the world, yet of course, I think he's quite handsome. I'm not so sure that if we could choose superficial traits that we'd all go the same route. I'm light-complected, but if I could choose, I might choose somewhat darker skin for my child, partly for aesthetic reasons, but also so they would be more protected from skin cancer. And then, just as the fashion world shifts radically over time, one could imagine that people might make choices that buck the norm so their children might be noticed and not swallowed up in a crowd. Sort of like naming your daughter 'Moon Unit.' ;)

  119. evolution by reallygettingannoyed · · Score: 1

    just pointing out some reasons why i don't think this is the greatest idea. Evolution depends on three things 1. Mutations 2. large genetic pool 3. recombinant reproductive practices one more thing...when humans began to move bipedally the problems associated with bipedal locomotion weren't weeded out. we were given longer and differently shaped legs.

  120. Did you know? by MagnusSt · · Score: 1

    That back in the 70's there was a papal decree against organ transplants? Organ transplants at the time were very contraversial! Of course I am uncomfterble with some of the posibilities of gene therapy, any thinking person will be that. However, we have to balance that with the need to help people who are sick, and in real need.