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Scientists Creating Life From Scratch

Rubberbando writes "MSNBC is running a story about bioengineering organisms to do specific tasks such as produce hydrogen or ethenol. It also goes into the risks and ethical issues of playing with this sort of science. Some of the scientists involved are saying it's more of an art instead of a science due to its 'biohacking' style of experimentation."

355 comments

  1. Becoming a god by helioquake · · Score: 3, Insightful

    This type of biological research convinces me firmly that
    the intelligent design (ID) is just another horse crap
    made up by humans. The base of ID's claim lies on the belief
    that the design of some rudimentary living organisms are
    just too complex to be built by accident. Hence
    some higher intelligence -- beyond human intelligence --
    must be involved in creating such organisms. But now, we
    are stepping closer to make one on our own. What does that
    say about humans? Are we becoming a god?

    No. It's all about perception. From our point of view, some
    things may look too complex to be formed accidentally. But
    as science advances, our perception does evolve (or should).
    If our society continues to exist (not sure if that happens
    in Kansas or in Bill Frist's home, but let's not go there),
    then what it seems an impossible task may not be so impossible
    any more.

    Well, that's my opinion and I'm sticking to it.

    1. Re:Becoming a god by jarich · · Score: 4, Funny
      Well, that's my opinion and I'm sticking to it.

      Good for you! That's following the scientific method! Keep that mind closed up tight! ;)

    2. Re:Becoming a god by Chosen+Reject · · Score: 3, Insightful
      The base of ID's claim lies on the belief that the design of some rudimentary living organisms are just too complex to be built by accident

      I'm not saying anything for or against ID, but if they claim it couldn't happen by accident, then humans doing it on purpose doesn't really disclaim that.

      -1 Faulty logic.

      --
      Stop Global Warming!
      Just say no to irreversible processes!
    3. Re:Becoming a god by Nuclear+Elephant · · Score: 4, Insightful

      This type of biological research convinces me firmly that the intelligent design (ID) is just another horse crap made up by humans. The base of ID's claim lies on the belief that the design of some rudimentary living organisms are just too complex to be built by accident.

      The fallacy in your statement is in the fact that these organisms weren't merely created by accident - they were intelligently created by scientists in a lab. So the fact that this occurred only reinforces the supposition that it could not, in fact, happen on accident. As far as the supernatural beings requirement, manufacturing simple organisms is one thing, but we are still infinitely far off from being able to manufacture another human (at least without a few beers and some luther vandross). Put simply: they just proved intelligent design could occur.

    4. Re:Becoming a god by nharmon · · Score: 5, Insightful

      Thats funny, because the article doesn't mention anything about creating life accidentally or in a manner than could occur in nature. On the contrary, it mentions that the scientists are "mixing, matching and stacking DNA's chemical components like microscopic Lego blocks in an effort to make biologically based computers, medicines and alternative energy sources."

      If anything, this solidifies intelligent design's viability as an alternate theory. After all, this new life was INTELLIGENTLY DESIGNED!

    5. Re:Becoming a god by AKAImBatman · · Score: 5, Insightful

      Or it could be that you didn't read the article, thus you don't realize that this isn't really "From Scratch." In fact, you probably don't realize that the article talks about injecting custom DNA into a pre-existing organism.

      The true test of creating new life "from scratch" is still not even close to coming to frutition.

      But don't let that stand in the way of a good rant. We all love a good rant. :-)

    6. Re:Becoming a god by thc69 · · Score: 4, Insightful

      Not that I am a big supporter of ID (especially the now common lobbying that it be taught as/instead of science)-- I prefer to believe in evolution, but by your argument, this offers support for ID, not against it.

      See, by your logic, this proves that intelligence can brew life from no life...thereby supporting ID.

      Tangent: Personally, I've never understood why science and religion must be at odds. Why can't one's deity be the one who caused these scientific laws and phenomena, and either nudged evolution a little bit here and there or maybe just planned it all in the beginning (like writing a program, or planning a chess game ahead) and set it loose?

      --
      Procrastination -- because good things come to those who wait.
    7. Re:Becoming a god by punxking · · Score: 1

      I don't think I could recreate another human life with Luther Vandross no matter how many beers I had...

      --
      You can have my cynical agnosticism when you pry it from my cold, dead logic.
    8. Re:Becoming a god by servognome · · Score: 1

      Hence some higher intelligence -- beyond human intelligence -- must be involved in creating such organisms. But now, we are stepping closer to make one on our own. What does that say about humans? Are we becoming a god?

      I don't think Intelligent Design necessarily states it has to be an intelligence beyond humans. It states that natural processes is insufficient to explain the development of organisms, therefore some sort of intelligent manipulation was involved. I don't see how intelligent manipulation by people to create new organisms refutes that argument.

      Not saying ID is right, just that this particular field of science doesn't directly refute its claims

      --
      D6 63 0D 70 89 81 BB 8E 7B 7C 5F 5D 54 EA AB 73
    9. Re:Becoming a god by Mateorabi · · Score: 1
      > What does that say about humans?
      >It's all about perception. From our point of view, some things may look too complex to be formed accidentally.

      And having an intelligent being (a human scientist) create life is evidence in favor of evolution over intelligent design how? If anything it will encourage the creationist (excuse me, intelligent design) camp more.

      Not that I believe their nonsense. That life can be created from scratch by intelligece doesn't mean that our life was created that way. But then the I.D. supporters aren't exactly a paragon of logic either.

      --
      "You saved 1968." - Ms. Valerie Pringle to the crew of Apollo 8

    10. Re:Becoming a god by perly-king-69 · · Score: 3, Insightful
      Feed the troll? You ARE the troll!

      Man invented God, not the other way round. That's intelligent design.

      --

      --
      This sig is inoffensive.

    11. Re:Becoming a god by Anonymous Coward · · Score: 0

      Eh, whatever.

      All they're proving is that it life can be created by intelligent beings and not that it creates itself.

    12. Re:Becoming a god by Anonymous Coward · · Score: 0

      I see you aren't exactly a paragon of tolerance either...

      I certainly lean more towards the theory of evolution, but by saying that intelligent design is absurd is EXACTLY the same as creationists saying that evolution is absurd. There is absolutely no difference because both statements are examples of people closing their mind to an idea simply because it contradicts what they believe. As a man of science I never close my mind to an idea or principle that cannot be proven false without doubt. I also do not close my mind to the beliefs of others and simply write them off as whackos because I don't agree with their beliefs. The only people who I do not tolerate are those who immediately classify someone as unintelligent simply because they believe something different. This might make me a hypocrite in a way, but so be it.

    13. Re:Becoming a god by Vancorps · · Score: 1
      I'd say it was designed, I'm unsure as to if the scientist actually knew what would be produced with absolulte certainty.

      Also, these organisms were created over the last 30 years of human knowledge. The rest of the world had billions of years to arrive where we are now.

      I won't hazard a discussion about where all life came from but the two competing theories in my mind don't compete. In reality evolution doesn't explain where it all began, only how we arrived where we are today. Picture it like traveling across the United States. Just because you know the roads that were taken doesn't necessary mean you know where I started the trip. You have enough information to hazard a guess, then again, if I told you I took I10 to get to AZ that wouldn't be enough information. I could be from California or I could be from Florida or any number of places in between.

      I'd say let's keep looking and learning for ourselves, share what we've experienced, and move on and build off of eachother rather than tearing everything down.

    14. Re:Becoming a god by Anonymous Coward · · Score: 3, Funny

      Oh great, that means that for unknown millenia there has been a deity sitting somewhere listening to complaints on war, famine, disease, etc and saying: "thats not a bug, its a feature"?

    15. Re:Becoming a god by shawb · · Score: 1

      They're really not creating life from nothing, that's just pure propoganda. From the actual meat of the article I couldn't find anything that they're doing different from traditional genetic engineering. Maybe they can now write up what they want the DNA strand to look like after they're done, but they can't create an ad-hoc strand, it's still just splicing in genes from other organisms, and then injecting that into an already living cell. No new life; this is simply an alteration of existing organisms.

      --
      I'll never make that mistake again, reading the experts' opinions. - Feynman
    16. Re:Becoming a god by Anonymous Coward · · Score: 0

      The argument of ID is not that God /could/ make organisms, but rather that only something intelligent could give rise to the life we see. Us creating more life doesn't actually prove or disprove it. What would prove or disprove ID is showing accidental life creation, or the inability.

      However, that takes a lot of time. So if it doesn't happen in X billion years, ID guys can say "Hey, we win", 2 years before life spontaneously creates itself. But then the ID guys bow and say "God did it!", because we didn't see the cause here.

      That is why ID doesn't have any validity, because you can /claim/ it is valid, because the core aspects are fundamentally unprovable or disprovable until we figure out who this god person is anyway.

    17. Re:Becoming a god by Anonymous+Crowhead · · Score: 1

      As a man of science I never close my mind to an idea or principle that cannot be proven false without doubt.

      But you open your door when you leave your house because there is abundant evidence that you can't walk through it. Is it possible? Yes. Is it probable? No.

    18. Re:Becoming a god by ScentCone · · Score: 1, Interesting

      I mean, if we can create an organism, why couldn't some higher being?

      Well, because we have hands and whatnot, as opposed to imaginary magical, worshipper-fueled, fantasy Santa-Clause-like mythological constructions that are easier to dream up than complex biology is for a lot of people to understand. Pretty much that's why. I think it's a lot like wondering why the breakfast you're eating, as just made by your mom, isn't an indication (or proof, even) that the Easter Bunny could also have made breakfast. Someone who is comforted by the image of the Easter Bunny making them breakfast is always goint to be able to say that maybe, just maybe Mom was sidelined while the rabbit scrambled the eggs. Never mind that Mom can stand right there and show breakfast being made, and even point out how that goes a long way to explaining how lunch will be made later in the day... there's no point explaining any of that to the True Believers.

      --
      Don't disappoint your bird dog. Go to the range.
    19. Re:Becoming a god by Salis · · Score: 1

      The methods are the same: splicing, mutating, and ligating DNA.

      But the thought behind WHAT to splice, mutate, and ligate is very different. They use engineering and mathematics to _predict_ what will work _before_ they build it.

      So it's not the trial and error prone protocol of traditional molecular biology. It's more like real engineering.

      (Or, what, did you think they create a million different skyscrapers and the one which stays up is copied?) ;)

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    20. Re:Becoming a god by ucahg · · Score: 0

      Given the trend I'll probably get modded down for this. Good thing I don't care about my karma...

      Anyway, how was he the troll? The first post could be construed as troll, but how is the grandparent trolling? All he did was question the premise of the first post. He didn't even outright say anything, he just asked?

      And how is the parent not a troll? Insightful? "Man invented God, not the other way round." Not only is that patently unprovable, it is a complete and definite kick in the face to all those who do believe in God or another deity. If it were backed up with some sort of argument or insightful ideas, then maybe it could be "insightful". As it stands alone though, I see it as troll.

      Oh well, slashdot's community mind hard at work I suppose.

    21. Re:Becoming a god by MillionthMonkey · · Score: 1

      If anything, this solidifies intelligent design's viability as an alternate theory. After all, this new life was INTELLIGENTLY DESIGNED!

      That's a little like drawing a circle around a can of beer and then claiming that all circles that occur in nature were drawn around beer cans.

    22. Re:Becoming a god by shawb · · Score: 1

      Traditionally, that's kinda of what they did with genetic engineering, build a million different skyscrapers and engineer in something to tell them whether the skyscraper stoof up... usually an odd DNA sequence that a flourscent marker die binds to.

      I appreciate that they are putting thought into this, but the article didn't actually go into any of the METHODS used for actually splicing the DNA sequence. All the ones that I know about are basically A)splice it into a retrovirus, infect the host with a virus and hope the retrovirus recombines in the right place or B)coat a nonreactive particle with the desired DNA and literally fire it into the cell, hoping that the DNA recombines with the host in the right way.

      Now, it is possible that they have somehow devised a way to say "I want this chunk of DNA to go into this segment of this chromosone" but I really doubt that our tech is there yet. And then knowing whether the copy of DNA will actually transcribe in the intended way is a completely different thing. With amino acid encoding sequences between some organims (pretty rare, and it's generally the Archaea that have anything actually different in terms of this, but it does happen,) various extra-nuclear editing process, transcription factors which determine when and how much RNA to transcribe, helper proteins which fold the protein into the desired shape and then move it along the cytoskeleton to the proper place... and then of course not knowing if this new protein will have any negative interactions with the host cell, it's not at all like building a skyscraper. I'm assuming they still try thousands upon thousands of trials, and then simply clone off the one that happens to work, hopefully getting to the point of breeding with standard techniques (But that's just to get the seed, you generally only want F1 crosses as your product to ensure that what you put in stays in.)

      --
      I'll never make that mistake again, reading the experts' opinions. - Feynman
    23. Re:Becoming a god by DarkOx · · Score: 0, Offtopic

      Well, to answer your question God did make us in his own image and did give use many many gifts, including our thoughts and feelings. The article talks about building an organism not string up a bunch or random chemicals and seeing what happens. Its sounds an awful lot like a simpler less devine more human act of ID to me.

      --
      Repeal the 17th Amendment TODAY! Also Please Read http://www.gnu.org/philosophy/right-to-read.html
    24. Re:Becoming a god by homebrewmike · · Score: 1

      Bah, don't be a dumb ass. The sentiment was a typical closure. The guy is most likely objective.

    25. Re:Becoming a god by Salis · · Score: 1

      They're not revolutionizing the methods, per say. They're using them in different ways. For example, a group at MIT created 'BioBricks'. They are segments of pre-synthesized DNA sequences which can be ligated in any order you wish using the same exact procedure. The bricks are specially constructed (with specific restriction sites) so that the same protocol can be used over and over again to continually ligate together more and more BioBricks.

      That way, you identify what you want to build and then you ligate together the bricks that contain each individual 'part'. They're 'replaceable parts'.

      But they use the same ol' genetic engineering techniques to splice, mutate, and ligate those bricks: restriction sites, PCR, electrophoresis, antibiotic selection.

      The methods that you listed are usually used for mammalian cells. Most of these guys use yeast or bacteria for their work. If you're working on bacteria, you can create single or multiple copy plasmids or integrate a plasmid into the bacteria's chromosome. If you're working on yeast, you can use homologous recombination to target the location of integration.

      For bacterial and yeast cells, it's very well known how a gene is transcribed and translated into protein and what other proteins are involved. Because we know how the system generally works, we can accurately describe it using mathematics. Then we can use the mathematics to predict what will happen if we cut out portions of the system and paste them in different combinations.

      The prediction part is the real revolution.

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    26. Re:Becoming a god by mark-t · · Score: 1
      Actually, the fact that our universe has not been around forever does not rule out infinite civilizations.

      It just rules out infinite civilizations that originate within our universe's past.

      Perhaps the "first" civilizations were intelligently designed by a species from our own universe's distant future, or perhaps a civilization that predated the big bang (in what for all intents and purposes was another universe) discovered or somehow evolved a way of getting into this one, where they created some life here and moved on. Who knows?

      ID does not necessitate the existence of God... although it so closely parallels it that many automatically assume that ID implies a religious view.

      I don't say I subscribe to ID, but us creating life from non-life does seem to support the notion that ID might at least be a plausable explanation for how we got here, even if it does rub those that don't want to believe it the wrong way. After all, we have not yet seen life come from non life _without_ intelligent intervention, and we do not yet have any substantiated evidence that it is even possible in actuality. The mere fact that we are here is not evidence either way because our own origins are what are being questioned in the first place with theories like ID and evolution.

      It may very well be that we are the product of both evolution _AND_ ID... who is to say for certain? I know I sure won't.

    27. Re:Becoming a god by shawb · · Score: 1

      Ahh... now THAT's kinda what I wanted to see in the article.

      --
      I'll never make that mistake again, reading the experts' opinions. - Feynman
    28. Re:Becoming a god by Dantoo · · Score: 1

      First Post! (At least I can't remember posting before) :)

      http://www.theonion.com/news/index.php?issue=4133& n=2/

      Link is to the Onion and their coverage of "Intelligent Theorys".

      I oft see much mention and debate on the "Scientific Method." So many of the discussions fall apart in semantics and basic misunderstandings of the subject material. Perhaps a basic refresher may help?

      Please allow me a moment or two to quote from my old friends Crockford and Knight on the The Scientific Method:

      "An interest develops in a certain phenomenon. The phenomenon is then subjected to close study and investigation to see whether any orderly set of conclusions can be formed. Usually the first conclusions are only qualitative statements of behaviour. With continued experimentation and refinement of techniques, it often becomes possible to draw quantitative conclusions. When well-defined mathematical relations are discovered, they are are termed laws. A law, then, is a mathematical statement of regularity of behaviour. The ideal gas law, for example, is a a mathematical expression for the quantity-volume-pressure-temperature relations in a gas. A further accumulation of data may show a given law to be only approximate and may lead to a more exact expression than was at first attained.

      The next step after the development of a law or a set of laws is to work out a hypothesis, which depicts a mechanism that explains the observed phenomena and the conclusions reached in the laws. If the hypothesis explains a number of laws and if predictions based upon it prove to be correct, it becomes a theory. A theory may be looked upon as a well established hypothesis. The great value of a theory or a hypothesis rests not only on the fact that it explains already established laws but that it enables the investigator to predict other laws and to formulate experiments to test those predicted laws."

    29. Re:Becoming a god by bmgoau · · Score: 1

      To cave men a modern car would look so complex it would have to be made by a devine being.

      In World War 2 when cargo aircraft were flying over pacific islands many of the primal natives developed the idea that these planes were huge bird gods.

      There are many imaginative situations when technology and structure astounds us, and for some so much so to the point that they believe it is magic or work of a higher being.

      Any sufficiently advanced technology is indistinguishable from magic. ~Arthur C. Clarke

      It is these type of thoughts that sloq progress and fuel ignorance.

      Just because something appears complex now does not mean that it is the creation of a devine being, as human technologies have evolved, it is possible to see that biology haveing several hundred million years to perfect itself would have come to an outcome we see now.

      Understanting the world around us is part of our purpose, complexity is no evidence of the existance of a god because complexity is realative to the technological context of the time.

    30. Re:Becoming a god by ozmanjusri · · Score: 2, Insightful

      wouldn't this be evidence for intelligent design? I mean, if we can create an organism, why couldn't some higher being?

      The suggestion that some theoretical higher being could create life was never in dispute. What is in dispute is whether the higher being exists.

      Showing that humans can create life demonstrates that, while God may have created life, (s)he is not necessary for its creation.

      --
      "I've got more toys than Teruhisa Kitahara."
    31. Re:Becoming a god by Anonymous Coward · · Score: 0

      The sentiment was a typical closure.

      "A conclusion is the point where one gets tired of thinking."

    32. Re:Becoming a god by arminw · · Score: 1

      ....Perhaps the "first" civilizations were intelligently designed......

      That just pushes the problem back one or more levels. Where did these conjectured civilizations come from? The choice of origins is either randomness or ID. Even by having life all around us as an example, human intelligence so far has been insufficient to come up with anything even close to creating life from "scratch". It reminds me of the story where some scientists of the future came before God, claiming they had created human being. God said: "Very interesting, show me how you did that." The scientists proceeded to take some dirt and were about to manipulate it into a human form when God stopped them with: "Hey wait a minute! You create your own dirt!"

      The Bible portrays the Creator God as the trancendant, "I am", the eternally self existing one. The concept of such a being is beyond our human logic or understanding and that is why God tells us that "Without faith it is impossible to please God" He can neither be proven nor disproven by human thinking.

      Those promulgating random impersonal processes over ID often mention that these processes operate by "natural laws" but are at a loss to explain how these laws came to be and how they all seem to fit together so exquistely to allow us to be here and question the existence of Giver of these laws.

      --
      All theory is gray
    33. Re:Becoming a god by rinkjustice · · Score: 2, Interesting

      Tangent: Personally, I've never understood why science and religion must be at odds. Why can't one's deity be the one who caused these scientific laws and phenomena, and either nudged evolution a little bit here and there or maybe just planned it all in the beginning (like writing a program, or planning a chess game ahead) and set it loose?

      Science helps us understand how God did it. I believe God will never break a law of the Universe. Why should He?

    34. Re:Becoming a god by Anonymous Coward · · Score: 0

      The base of ID's claim lies on the belief that the design of some rudimentary living organisms are just too complex to be built by accident. Hence
      some higher intelligence -- beyond human intelligence -- must be involved in creating such organisms.


      No, ID does not say that the intellegence must be "beyond human intelligence." I'm not an ID proponent, but the ability of humans to design life would support, not discredit, ID. Your analysis is completely backward.

    35. Re:Becoming a god by argStyopa · · Score: 0, Troll

      And that's a particularly good exercise of the ID method: miss the point, ignore the facts, and instead make a snide ad hominem attack.

      Good for you! Keep that mind closed up tight!

      --
      -Styopa
    36. Re:Becoming a god by iq+in+binary · · Score: 1

      As man is now, god once was. As god is now, man will once be.

      -Pearl of Burdon

      You'd be surprised how much has been predicted by religious literature ;)

      --
      Of all the Universal Constants, here's one I know: Nice guys finish last ;)
    37. Re:Becoming a god by aichpvee · · Score: 1

      Stop encouraging creationists. It isn't helping anyone, especially when you try to use something completely unrelated as the basis for that encouragement.

      --
      The Farewell Tour II
    38. Re:Becoming a god by Anonymous Coward · · Score: 0

      Scientists will never be able to create life. But they can create the bodies. The difference is unless there is a soul occupying the body it will never be alive. Consciousness is the symptom of the soul. Once thats identified we know its alive.

    39. Re:Becoming a god by wildchild978 · · Score: 2, Insightful

      fairly succinct, except you omitted the conclusion jumping that people will make regarding "creating life" when all they're really doing is manipulating pre-existing life. Analogy: I have five mates with five computers, all built at the computer factory. I take one mate's mother-board, PSU and case. One mate's CPU and RAM, one mate's HDD and CDROM, ones monitor, keyboard and mouse, and my last mates video-card and all the required cables. I then release a press statement saying I've created a computer from scratch. In reality I've done nothing of the kind. Rather, I've ripped my mate's computers apart and assembled my own out of their spare parts. All without acknowledging the computer factory that built the five other computers.

    40. Re:Becoming a god by smallfries · · Score: 1

      But do you really believe the meat of the article when it contains such gems as 'J. Craig Venter, the entrepreneurial scientist who mapped the human genome'. Dodgy journalism at best, outrageous rewriting of history at worst... Good 'ol MSNBC.

      --
      Slashdot: where don knuth is an idiot because he cant grasp the awesome power of php
    41. Re:Becoming a god by gowen · · Score: 1
      So the fact that this occurred only reinforces the supposition that it could not, in fact, happen on accident.
      NO. It says nothing about whether this may or may not've happened by accident. It says that designed life is possible, but no scientitst ever doubted that. The fact that life can be designed tells us nothing about whether it actually was or not. And the vast majority of the evidence still points to "not".
      --
      Athletic Scholarships to universities make as much sense as academic scholarships to sports teams.
    42. Re:Becoming a god by Anonymous Coward · · Score: 0

      The fallacy in your statement is in the fact that these organisms weren't merely created by accident - they were intelligently created by scientists in a lab. So the fact that this occurred only reinforces the supposition that it could not, in fact, happen on accident.

      If the scientist is manually creating circumstances that could occur by accident, then it most certainly does not reinforce the supposition that it could not happen on accident.

    43. Re:Becoming a god by cscoder · · Score: 1

      Understanding the universe goes far beyond creating 'life' in a test-tube. It's interesting to speculate, but I don't know how anyone can have an opinion about what the ultimate basis of reality is, as we perceive it.

      I like to think of god as being inherent in the laws of physics. Understanding of god increases as we leverage our abilities to understand the Universe. Speculation on whether there is an intelligent force behind the Universe is meaningless. Speculation on what constitutes (meta?) intelligence is interesting but also meaningless.

      All religions are so clearly pure mysticism that I have to assume that any intelligent person who 'knows' the nature of God or how God wants us (particularly me and mine) to behave either has a hidden agenda or is yet another victim of the religious mass-hysteria that evolved from metaphysical attempts to explain the universe long before the scientific method evolved.

      Hey, maybe it's all just the Matrix. If so, don't wake me, I got a good part.

    44. Re:Becoming a god by falconwolf · · Score: 1

      While I probably shouldn't feed the troll, wouldn't this be evidence for intelligent design? I mean, if we can create an organism, why couldn't some higher being? After all, I believe scientists still don't have a good explanation for how the first organism was created. Why couldn't a higher being have created it?

      I don't see either that it is evidence for ID or for design period. As far as I'm concerned I don't know if a "God" exists, eg I'm agnostic, "a" without and gnostic "knowledge". I simply don't know and don't believe either way.

      Falcon
    45. Re:Becoming a god by helioquake · · Score: 1

      I've gotta confess, I really was a TROLLfor this parent post.

    46. Re:Becoming a god by keraneuology · · Score: 1
      Hence some higher intelligence -- beyond human intelligence -- must be involved in creating such organisms. But now, we are stepping closer to make one on our own. What does that say about humans? Are we becoming a god?

      In a nutshell, yes.

      What are the requisite criteria to be considered "a god"? My personal opinion (well, more of a suspicion... my thoughts are always subject to change whenever I stumble upon something that I like better) (at which I have arrived with my own thoughts, ponderings and logic, if you have a different opinion I'm really happy for you, but this one is mine and you can't have it) is that "a god" is one who has perfect understanding of all natural laws and processes in the universe.

      I once presented a conceptual lesson plan to some staunch intelligent-design-is-impossible-evolution-is-the- only-right-thinking people - leaving out any conclusions or statements of what did happen I suggested that students be led through a discussion of what knowledge, technology and timeframes would be required to build a (fungus / fruit fly / wombat) from scratch. To me this is a perfect thought exercise and would cover all aspects of life, from physiology to biochemistry to genetic engineering, but to them the very question was proof positive that I was a world-created-in-144-hours crackpot ready to burn people at the stake for daring to mention heliocentricity.

      As in all cases, there are crackpots and extremists on both sides - the anti-evolutionaries ignore the magic of the color-changing moths and the anti-designers think that current levels of technology represent the high-water mark of knowledge in the universe and that nobody - past, present or future - has ever been or will ever be able to guide evolution on a planetary scale and that humans are unquestionably the result of accident and chance.

      --
      If the g'vt kept the data on you that google does you'd better believe you'd be calling it "doing evil"
  2. Don't they listen?? by Anonymous Coward · · Score: 5, Funny

    Why have these scientists not heeded the dire warnings of Jeff Goldblum? You cannot control your creations! Life finds a way!

    Their "science" and "bacteria" are going to cause random plot-convenient sex changes and bloody dismemberment of lawyers!!!
     
    ...well okay actually maybe this isn't going to be so bad

    1. Re:Don't they listen?? by null+etc. · · Score: 1

      Well, they need some way to fight off the sentient nanobots!

    2. Re:Don't they listen?? by bitweever · · Score: 1

      I believe the quote was, "Life, uh, finds a way".

      In this context however, when I read Goldblum's name, the first thing that popped into my mind was Goldblum's made-for-teevee movie about Watson and Crick, named Life Story. Watched it in biology class, it was interesting to see a young Goldblum complete with his sputtering speech style and spastic hand gestures years before he was Dr. Ian Malcom.

    3. Re:Don't they listen?? by Anonymous Coward · · Score: 0

      look there is no "art" to genetic engineering. it is extreemly complex how ever and you need to know a lot to be able to control your creations. if you think there is an art you dont belong in this feild because you clearly dont understand enough to let it get out of your control. and as far as the ethics, what is wrong with creating life (yes i know this god fellow made us all and he should be the only one with that magic art)there should be problem with this as long as we understand all the risks and prevent them

    4. Re:Don't they listen?? by uberdave · · Score: 3, Funny

      ... and bloody dismemberment of lawyers!!!

      You say that as if it's a bad thing.

    5. Re:Don't they listen?? by Conspiracy_Of_Doves · · Score: 1

      I think you missed the last line of his post.

    6. Re:Don't they listen?? by MutantHamster · · Score: 1

      But when will they engineer organisms who know how to spell "ethanol"?

      --
      My Greatest Heist - Muisc partly inspired by the unbeatable Qwantz
  3. Misleading Title by AKAImBatman · · Score: 4, Informative

    FYI, the title is incorrect. There is no "from scratch" component to the life. What they're doing is building custom DNA, then injecting it into a living cell.

    1. Re:Misleading Title by Anonymous+Crowhead · · Score: 1

      What they're doing is building custom DNA, then injecting it into a living cell.

      And they are hardly the first to do such a thing. This is just a "hey here's an interesting company" article. They rarely write a "hey, here's an interesting rearch technique that thousands of labs are using" article.

    2. Re:Misleading Title by morgan_greywolf · · Score: 1, Informative

      Well, in a sense, this is 'life from scratch'. Although the cell is living, they are still creating a new organism from that cell -- one that is not necessarily the same type of organism as the one the cell came from. This *is* a bit different than cloning in that reproductive material isn't being used. Besides, if you remove DNA/RNA from a cell, is it still a cell and is it still alive?

    3. Re:Misleading Title by AKAImBatman · · Score: 1

      Well, in a sense, this is 'life from scratch'

      More correctly, it's "synthesizing new organisms". "From Scratch" implies, well, that you started from scratch. i.e. Nothing. :-)

      Besides, if you remove DNA/RNA from a cell, is it still a cell and is it still alive?

      Irrelevent. We have the technology to reanimate bacteria. However, we don't have the technology to construct a living bateria.

      This story is a bit like all those cutsey headlines, "Faster Than Light Achieved! Einstein Wrong!" Then you go read the article and find that no relativity violation occurred, and that the FTL transmission had an *effective* speed of light.

    4. Re:Misleading Title by shawb · · Score: 1

      The tagline says 'Synthetic biologists' build with one genetic molecule at a time. To me this says that they're engineering genes themselves basepair by basepair, but that's really not what's going on. This is just the same genetic engineering that's been going on for a long time, maybe just throwing genes from multiple organisms into one, which really isn't that big of a deal. I doubt they even have a revolutionary back end which improves the process. The whole thing just reeks of A)poor sensationalist journalism or B) corporate advertising.

      --
      I'll never make that mistake again, reading the experts' opinions. - Feynman
    5. Re:Misleading Title by MadJoy · · Score: 1

      That's because we don't have the technology to physically build a bacteria cell, not because we wouldn't know how to. And nothing wrong with calling it "life from scratch" so that people too stupid to make any sense of "synthesizing new organisms" can feel a little more educated about the goings on of the world. It's such a small question of semantics.

    6. Re:Misleading Title by Neil+Blender · · Score: 1

      That's because we don't have the technology to physically build a bacteria cell, not because we wouldn't know how to.

      Both our current knowledge and technology are not sufficient to build a cell from basic components. Both are a long, long way off.

    7. Re:Misleading Title by braindead · · Score: 2, Informative

      You're right, the only problem with the summary is a problem of semantics. That is, the title says something that is not true, because it uses a word that has the wrong meaning (semantics=the meaning of language).

      Another way of saying the same thing would be that everything is wrong with the summary. After all, this is text we're talking about; isn't meaning the whole point?

    8. Re:Misleading Title by STrinity · · Score: 1

      Well, in a sense, this is 'life from scratch'

      No, not really. If I told you I built a car from scratch, would you think I pimped my ride, or built a completely new vehicle from spare parts? Saying someone created life from scratch suggests abiogenesis, which would be a truly phenomenonal acheivement, whereas gengineering some bacteria is common place.

      --
      Les Miserables Volume 1 now up with my reading of
    9. Re:Misleading Title by kfg · · Score: 2, Insightful

      No, not really. Based on the title I was hoping for a story on synthetic abiogenesis.

      Life truely from scratch is the, ummmm, "Holy Grail" of the life sciences. The true uncharted territory.

      This is just another story about genetic engineering.

      KFG

    10. Re:Misleading Title by hackwrench · · Score: 5, Funny

      A group of scientists decided that mankind had advanced far enough that they no longer needed God. So they drew straws, and the loser went to find God. When he found Him, he dithered a bit, made some small talk about the weather, and finally came out with it.
      "OK, look God," he said, "We've mastered space exploration, we can cure any disease, we can talk instantaneously with people around the world, we can clone human beings; basically, we don't need you any more."
      God listened patiently. Finally He spoke.
      "Tell you what," He said. "We'll settle this with a man-making contest. Each of us will make a man, and the first one to finish wins."
      "Sure," said the man, who headed off to consult with his colleagues.
      "Wait a minute," called God.
      The man turned.
      "We're going to do this the real way; the way I did it in the beginning."
      "No problem," responds the man, bending down to grab a handful of clay.
      "No, no, no," says God. "You get your own dirt."

    11. Re:Misleading Title by Salis · · Score: 1

      Well, the difference is the 'engineering' part. They're not cutting, splicing, or mutating large stretches of genes in the hope that it will confer some phenotype. They're using mathematics to _predict_ what will happen if they construct a specific stretch of DNA.

      (I actually do research on the math part of this. And some on the building.)

      -Howard

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    12. Re:Misleading Title by digidave · · Score: 3, Funny

      In order to make an apple pie from scratch, you must first create the universe.

      - Carl Sagan

      --
      The global economy is a great thing until you feel it locally.
    13. Re:Misleading Title by cution · · Score: 1

      That's basically like saying, "Sorry, guy, you aren't making bread from scratch! You're mixing flour and eggs and water!"

      You might as well say nothing is made from scratch since EVERYTHING is made by manipulating pre-existing ingredients.

    14. Re:Misleading Title by IronChef · · Score: 1

      FYI, the title is incorrect.

      That's not true... that's impossible!

    15. Re:Misleading Title by Tony+Hoyle · · Score: 2, Insightful

      This is 'life from scratch' in the same sense that writing a plugin for firefox is 'creating a browser from scratch'.

      It would be interesting to try to argue your way around the GPL using that reasoning ('yes your honour I wrote it from scratch using two existing GPL programs that I put together, so the GPL doesn't apply').

      The case might last, um... 15 seconds..?

    16. Re:Misleading Title by nospam007 · · Score: 1

      >> FYI, the title is incorrect. There is no "from scratch" component to the life. What they're doing is building custom DNA, then injecting it into a living cell.
      ---
      But nonetheless in this case it _is_ intelligent design.;-)

    17. Re:Misleading Title by Anonymous Coward · · Score: 0

      And nothing wrong with calling it "life from scratch" so that people too stupid to make any sense of "synthesizing new organisms" can feel a little more educated about the goings on of the world.

      Well, actually a long time ago a bunch of "scientists" started giving their own versions of possible explanations on origins of the universe. Then some idiot, to simplify it, started calling it a fact. And now most high school students graduate thinking that evolution is not only a proven fact but that anybody that disagrees with it using scientific data is not using "science". So it should be explained as it is.

    18. Re:Misleading Title by Anonymous Coward · · Score: 0

      I don't get it, can someone explain it for me?

    19. Re:Misleading Title by moz25 · · Score: 1

      The amusing thing of such stories is that even the ones portrayed as critical or not religious still somehow manage to accept the deity in some manner.

      The reality, however, is that in spite of people calling on their deity to take actions in the physical world, this deity's actions is consistent with the actions of a deity that does not exist or is not involved with mankind.

      I would say: post your joke in a medium that does not need science to build or sustain it.

    20. Re:Misleading Title by kmac06 · · Score: 1

      The joke is that the scientists need to create matter from nothing to be able start out the same way God did.

    21. Re:Misleading Title by UnapprovedThought · · Score: 1
      "No problem," responds the man, bending down to grab a handful of clay.
      "No, no, no," says God. "You get your own dirt."

      "Poof!" Just then the devil appears carrying a briefcase, whispers something into the scientist's ear and disappears.
      "OK," says the man, "you win that one, but I have a tougher challenge for You."
      "What?" God replies confidently.
      "Let's see who is the first to make a man out of freshly made feces."
      "Pshaw, that's easy," dismisses the deity.
      So the man stoops down to begin making the materials, and just then receives a tap on the shoulder.
      "Uh, let Me have some of that..."
      "No, no, no," says the man "you're so perfect, let's see you make your own $!*#."

  4. Biohacking by daeley · · Score: 5, Funny

    Scientist #1: I am teh l33t bi0hax0R!!!!1111!lol!!!

    Scientist #2: LOL j00 r bi -- ur teh ghey!!!

    Scientist #1: STFU, n00b!111!

    --
    I watched C-beams glitter in the dark near the Tannhauser gate.
    1. Re:Biohacking by peculiarmethod · · Score: 1

      making fun of people who can't pronounce words properly? ummm.. no. Leet speak came from BBSs back in the 80s.. there were regular open invite BBSs, and there were ELiTE, or Underground BBSs that required invitation from someone already onboard, or proof of your being ELiTE, usually requiring your finding the number on another elite system, and filling out an application which consisted of tests.. usually asking your to define LEET words or acronyms.

      so yeah. you're wrong.

      --
      ** "It's not my job to stand between the people talking to me, and the ones listening to me." -- Pego the Jerk
    2. Re:Biohacking by Anonymous Coward · · Score: 0

      Let me carry this out to it's idiotic end:

      Scientist #2: d00d, what's teh point????

      Scientist #1: Profit!!!!

    3. Re:Biohacking by Anonymous Coward · · Score: 0

      Won't someone think of the poor mentally challenged people on IRC?

    4. Re:Biohacking by Anonymous Coward · · Score: 0

      you are teH Gh3y for knowing this.

    5. Re:Biohacking by Anonymous Coward · · Score: 0

      This is true.

    6. Re:Biohacking by Anonymous Coward · · Score: 0

      i belive the man refers ot how ironic tha everage lsasdotter would belittle leetspeek as we are all functional illiterates here.

      ergo

      "you must be new here"

    7. Re:Biohacking by hexed_2050 · · Score: 1

      Those were the days, BBSs and 2400 baud modems. Everytime I download something at 10Mb/s, I always remember how it took me 14 minutes to download something at 14.4bps.

      Funny thing is, most people who think they are "gods of computers" never even experienced any real computer communities before the mid 1990s and the bubble.

      --
      Valkyrie is about to die! Wizard needs food -- badly!
    8. Re:Biohacking by Mycroft_VIII · · Score: 1

      I've had the handle Mycroft since spring 1984 (WWIV, MTABBS, Color64(co-ran one of those for a time), etc.) but I don't think I'm a computer god, mid grade priest with a few minor miracles perhaps.
          But yeah, those WERE communities back then. Imagine 20+ people who'd mostly never laid eyes on each other, yet had known each other for many a moon finally getting together at a roller rink. A strange sort of akwardness for a while that just evaporates as people start talking and quickly forget thier mental images of each other and start remembering the PERSON thier talking to. As much as I like the net, it didn't come without without a price that still leaves me a bit sad.

      Mycroft

      --
      https://signup.leagueoflegends.com/?ref=4c3ed6600b6ea
  5. I am going to sue by Anonymous Coward · · Score: 5, Funny

    I hold rights to all life and I will see you in court.

    God

    1. Re:I am going to sue by Anonymous Coward · · Score: 5, Funny

      I hold rights to all life and I will see you in court.
       
      God


      Yea right, like you have any lawyers up there!

    2. Re:I am going to sue by NiceGeek · · Score: 1

      You again? I thought Oolon Colluphid took care of you for good.

    3. Re:I am going to sue by rovingeyes · · Score: 1

      Thats a tragedy - God trying to prove to humans in humans' court that (s)he created them.

    4. Re:I am going to sue by soulctcher · · Score: 1

      I'm fairly certain, there's definitely prior art in this case.

    5. Re:I am going to sue by rovingeyes · · Score: 1

      Prior art? This is not a patent application! God is claiming that (s)he has copyright on creating life.

    6. Re:I am going to sue by f0dder · · Score: 1

      RAmen

    7. Re:I am going to sue by JPriest · · Score: 1

      Actually, Life is a TM that I own and you may use the word too as long as you give my $5,000.

      --
      Saying Java is nice because it works on all OS's is like saying that anal sex is nice because it works on all genders.
    8. Re:I am going to sue by bleaknik · · Score: 1

      Actually, Microsoft patented the technology behind "life" before you...

      --
      Deja Vu
      n. 1. The sensation that you've read this very article before.
    9. Re:I am going to sue by Torinir · · Score: 1

      He'll hire Satan's legal team. Only the best lawyers of all time reside in the deepest pits of Hell. :-p

    10. Re:I am going to sue by Spy+der+Mann · · Score: 1, Offtopic

      Yea right, like you have any lawyers up there!

      But He IS the judge. :)

    11. Re:I am going to sue by loose_cannon_gamer · · Score: 1
      I'm concerned that my first response to this was, "hey, all that unused DNA information is probably just the EULA"

      Somebody shoot me.

      --
      In Soviet Russia, us are belong to all your base.
    12. Re:I am going to sue by BerntB · · Score: 1
      Sooo.. God is the prosecutor , the judge and the hangman.

      Traditionally, he wears white, too?

      Figures.

      --
      Karma: Excellent (My Karma? I wish...:-( )
    13. Re:I am going to sue by demongp · · Score: 1

      I'll just make them.

  6. Hmm by MadJoy · · Score: 2, Insightful

    As I understand it, it's trying to make it into more of a science, where previously it had lacked order and had merely been creative guessing which genes to put where. Seems like a much better method to me - start from the most basic (well, almost most basic... genes -> nucleotides -> atoms -> quarks... but you get the gist) elements and put them together building-block style. Go modern science.

  7. Title misleading? by Swamii · · Score: 5, Insightful
    The article states,
    Though scientists have been combining the genetic material of two species for 30 years now, their work has remained relatively simplistic.

    Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.
    --
    Tech, life, family, faith: Give me a visit
    1. Re:Title misleading? by MadJoy · · Score: 2, Interesting

      Yes, but now they're going beyond that. They're trying to synthetically combine nucleotides of genetic material together in new ways. No more simple two species transactions, but a genuine "synthetic" approach to creating NEW genes.

    2. Re:Title misleading? by Cyno · · Score: 1

      Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.

      Its also illegal in some states, morally wrong in some religions, and offensive to some people. I just think its gross and they should keep that stuff in their bedroom.

    3. Re:Title misleading? by sillybilly · · Score: 1

      Silicon chip computers will be life from scratch, as soon as they get the capability to replicate themselves. We better regulate in advance, before someone does it. All this DNA hacking is just plagiarizing life from somewhere, unless they can really cook up a self replicating molecule, but that would start out something simple, that would only copy itself, probably even without some sophisticated cell structure like a bacteria would have it, but just pure DNA-like crap, like a virus.

    4. Re:Title misleading? by Vellmont · · Score: 1


      Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.


      I guess we don't all agree, because I don't. What does "from scratch" mean? In cooking it means taking basic ingredients and turning that into a finished product. Isn't DNA the basic ingredient to life? In cooking you can still use machines to do some of the work like a mixer, oven, etc and still have your product created "from scratch". Why isn't the same true in biology when you're using a cell as your machine to do some of the work?

      --
      AccountKiller
    5. Re:Title misleading? by forkazoo · · Score: 1
      Yes, but now they're going beyond that. They're trying to synthetically combine nucleotides of genetic material together in new ways. No more simple two species transactions, but a genuine "synthetic" approach to creating NEW genes.

      Recipe for pepperoni pizza "from scratch":

      Get pizza.
      Make pepperoni.
      Add second to first.

      It's not to say that the scientists aren't working hard, aren't smart, or haven't made a significant advance. They are making new genes and using them in living organisms. This is completely different from "life from scratch." Creating a life form, without using any existing parts, just chemistry, now *that* would be life from scratch. (Even if it happened to be an existing species!) It would be something fundamentally different from what has been done here.

      Scientists create new forms of life = true
      Scientists create life from scratch = false (for now)
    6. Re:Title misleading? by pinball667 · · Score: 0

      Although bricks may be the basic building blocks of many buildings they are not much without something to hold them together - you could whip up as much strands of DNA as you want, but it wouldnt do much good without all the other stuff cell around it.

      This does not discount what these scientists are doing at all, but unfortunatly it is going to give the ID dolts more reason to force their religious views on the children in US schools - "hey - if we can do it whats to prevent {INSERT FICTIONAL DIETY HERE} from doing it". Anyhow, as the universe is full of unlimited possibilities science theoretically leaves room for a "god" but in their minds there is room for nothing else.

      $KANSAS_JOKE_HERE

    7. Re:Title misleading? by arminw · · Score: 1

      ....Silicon chip computers will be life from scratch, as soon as they get the capability to replicate themselves....

      Such a ridiculous statement can only come from someone who has no idea how complex even a single cell, such as an amoeba is. All the computers in the world put together don't have as many individual parts all working together as one of these. Figure out how many atoms are in a single cell and all their interactions. Even the atoms themselves are complex devices operating according to exact, pre-established principles. A computer also consists of more than just a bunch of electronic parts. There is the matter of the software, created in the intelligent MIND of the programmer. In the same way, there is more to life than just an arrangemnt of atoms. There is a software program, if you will, that determines the operation of the living system, the biological hardware. Intimately knowing the physical construction of a computer reveals nothing about the function of its software. The same is true of living systems.

      --
      All theory is gray
    8. Re:Title misleading? by sillybilly · · Score: 1

      Proof of God.. here we go again. It's still a nonanswerable question. If you notice what Darwin said, was that you just put the rules and the right soup in place, the "software", or "chemical life" automatically appears, given billions of years. Throwing random data at a computer chip does not guarantee that a 'functioning' software will appear, 'functioning' meaning self-replicating, but given enough complexity - i.e. memory, processing power, and a few million years, I bet you some self replicating code will appear, without a 'programmer' in the picture. Should make a nice experiment. Of course if you have a programmer you can write that self replicating code in a few minutes, instead of having to wait a few million years, but don't underestimate the effectiveness of the impersonal and mindless time. The impersonal and mindless time can come up with very "intelligent designs", as long as you let it go through all the noninteligent ones too, and selectively filter the intelligent ones out. Natural selection - what's simpler than that? How we got here is one thing, even answerable, but what it means to be a human or conscious or sansient being, what the purpose of life is, that's quite another, unanswerable question category.

    9. Re:Title misleading? by sillybilly · · Score: 1

      Remember Wohler and urea? Only life can create organic chemicals? Only a MIND can create life? Quit thinking you're special, and recognize your true situation, become aware of your awareness without self glorifying bloat. You still are special because you are aware, but how about a dose of the attitude of the great indian chief, saying : "The Earth does not belong to us, we belong to it." You belong, you don't own. You are part of a bigger whole, and while you do have the 'self' functioning selfishly in this bigger whole, you'll lose your balance quickly if you turn arrogant and assert this 'self' too much, even in abstract ways, calling it MIND. Religion as the ultimate neurosis? Some kind of harmony is crucial. Even lions, sharks and wolves live in some kind of harmony with their environment, being an integral part of it, and without them the whole thing would collapse. If you pay attention listen closely, harmony is at the core of most religions, but sometimes things get taken out of context and people lose their "MINDs" very quickly.

    10. Re:Title misleading? by Anonymous Coward · · Score: 0

      When you cook from scratch you take something that a human has created (or has made a machine to create) like flour, sugar, etc. and combine it to make something. The human race already knows how to create flour, sugar, etc. When the human race is able to create a living organism 'from scratch' (no outside help from 'preprocessed' cells) then I don't see a problem with a scientist mixing and matching and calling it 'from scratch', until that point why don't we call it like it is. Scientists have recombine existing DNA (which they still don't know how to make 'from scratch') in a way that has not existed before.

    11. Re:Title misleading? by arminw · · Score: 1

      .....Darwin said, was that you just put the rules.....

      The issue that Darwin and his disciples never address is the question: Where do the rules "that run the soup" come from? Rules imply thought, programming, the product of mind. Software is not physical, although it can be carried by physical means.

      For a collection of parts (atoms) to become organized in a certain way requires the input of information. Observation shows that time is the enemy of organization through a principle called entropy. Never, ever has it been observed that a disorganized, random pile of parts became orderly without the input of BOTH information and energy. It has been shown scientifically and in everybody's experience that adding time does not EVER result in an increse of order, but all things tend to disorder and decay and death as time moves forward.

      So far at least, by the best efforts, man has not come anywhere close to even make a single living cell from non-living material. Yet you, and many others are willing to ascribe to blind chance over immense periods of time something that the best intelligence of scientists has not been able to duplicate. Is it not humiliating to think that impersonal blind chance is better at creating life than the best efforts of intelligent human scientists? I prefer to believe that a super-intelligent being, God, created and sustains us and everything we observe all around us. There is no way to "prove" there is or there is no God. Belief in a loving, personal God just makes a more satisfying explanation of what we observe all around than blind, impersonal chance.

      --
      All theory is gray
    12. Re:Title misleading? by sillybilly · · Score: 1

      Increase in disorder is pitted on our idea of "order." We are partial or biased toward a single state of a system (say a configuration of atoms in a gas) and label it "order", compared to all the myriad of other possible states. By statistics, rules of equivalence, chances of the system taking up any of the other "disorder" states are equal, but since there are so many more "disorder" states, overall the system tends to "disorder".
      Even a single state that you consider "disorder" is just as highly unlikely as your "order" states, so in effect there is no bias against order, but there is bias against statistical improbability. Is life, given enough time, a statistical improbability? Yes, unless you give it enough time, then, if conditions are right, sooner or later...

      In low energy systems, such as a lottery urn without the balls bouncing much, most balls accumulate on the bottom, and "order" is the dominant feature, if you prefer bunching all the low-lying states in the single "order" term. In a fully operating high energy lottery urn, disorder is dominant, and to maintain any kind of order by any kind of device, it would constantly need to consume energy, and create disorder somewhere else while maintaining its own order.

      Life is such an improbability, ordered state, but the very essence of life is maintaining improbability - there is a constant consumption of energy to repair and maintain order. Order is not improbable if the system corrects itself, and time natural-selects those systems that do correct themselves.

      In the beginning there was no special bias towards any kind of "life," there randomly formed molecules that did copy themselves, like DNA does, and those that did not copy themselves. Nobody cared. Time did the rest. Why do you need to summon an intelligent spectator to create these self-copying molecules, when they happen on their own? If you must look for "cause", you have to look at who caused the rules of nature that end up creating life, why are such rules there? Who caused the cause?

      Darwin said nothing about who caused the rules, he simply stated that if these rules exist, everything follows. He simply answered those questions which he could answer, without taking an arbitrary side on the questions he could not answer.

      As you say it, looking for cause of causes is where ultimately all philosophical discussions of God end up, pitted on the argument that everything must have a cause, therefore God is the root cause of it all. But such statements don't stand against the "if everything must have a cause, then what's the cause of the root cause?" Oh, the root cause is special, it's the only exemption. Says who? Why can't the laws of nature that cause everything, be the special, root cause? Basically, when it comes to religion, you have to leave logic and arguing alone, and it's just faith that you can go by.

      "Is it not humiliating to think that impersonal blind chance is better at creating life than the best efforts of intelligent human scientists?"

      No it's not, or yes it is, because there is nothing wrong with humility. I'm not special, you're not special, that's one thing darwinism teaches you, that's one thing that the heliocentric copernican astronomy teaches you, and the more we look around us, the more we realize just how much just a part of the whole we are, without being special, or above it all. You get to be less arrogant.

      "Belief in a loving, personal God just makes a more satisfying explanation of what we observe all around than blind, impersonal chance."

      Religion should concern the inner world, inner satisfaction, inner health. When it comes to the external world, religion is pitted against cruel science, that respects no stability, no dogmas, and religion keeps getting hurt, ouch! The World is only 6000 years old? The Earth is the center of the Universe? God provided you with the Earth, and all its animals and plants to feed yourself? (how easy do you want to make casting aside moral dilemmas?) Life is special, there is a livin

    13. Re:Title misleading? by arminw · · Score: 1

      .....The important point in all this religion is self control, inner peace, and awareness......

      Your whole post concerning religion is a good and thought out one. There are many religions and your summary of them is good and succinct.

      The God of the Bible is however not interested in religion, but relationship. The message of the Gospels is exactly the opposite of all religion. Religion is the striving of man to somehow reach the divine. The avenues through which man attempts this are numerous and varied. You gave a good outline of some of them. In the Gospels, the good news, we are told that God, took on human form and dwellt among us. He did this not to give us a set of religious rules, by the keeping of which we could reach God, but to show us the path to a relationship with Himself based on mercy and forgiveness.

      In Joh 14:6 it states: Jesus saith unto him, "I am the way, and the truth, and the life: no one cometh unto the Father, but by me."

      That statement is either arrogant, delusional, falsity on the part of the writer or it is true. If not true, then Jesus is certainly not worth listening to in whatever else He may have said or what is attributed to Him. It is a VERY narrow minded statement that excludes all other religions.

      We observe that the rules and relationships in nature are often very narrow and specific and if they were not, there could be no life anywhere. Water, unlike most substances, expands when it solidifies. If that were not so, there could be no life. The mass of the proton is exactly 1836 times that of an electron. If that were slightly different, atoms could not combine to form living things. Since the rules of the physical realm are quite narrow at times, it doesn't at all surprise me that when the Creator of these rules expresses an extremely narrow path to Himself.

      You, as well as every human on this planet, may freely choose to come to the divine by whatever religious effort you can muster, or you can respond to God's invitation of mercy as offered in Jesus Christ. I have chosen the mercy approach, because no human effort is sufficient to stand before the perfect Creator God of the Universe.

      This means, now, that I have been accepted mercy and forgiveness, I have with that mercy been given the grace and power to have "...self control, inner peace, and awareness......" and the privilege to now call God "My Father".

      --
      All theory is gray
    14. Re:Title misleading? by sillybilly · · Score: 1

      Please don't take any offense to this, but for whatever reason I get reminded of this story I heard on hard rock radio:

      It's 7 am, and the doorbell rings. I walk in by bathrobe, slippers and hot coffe mug to the door, to see who it is. It's a Jehovah's witness, asking me to accept the Lord as my Saviour. I scratch my head, and smile, and say, "No, not right now, but look, brother, it's quite early in the morning for this, would you like to come in and get a hot cup of coffee?"

  8. Indeed by Anonymous Coward · · Score: 1, Informative

    If you actually want to read about the project on creating life "from scratch", that would be here

  9. Creating life? by ryanr · · Score: 4, Funny

    Are they using the intelligent design method, or the waiting around to see what happens on its own method?

    1. Re:Creating life? by iggymanz · · Score: 1

      intelligent trial and error and design

    2. Re:Creating life? by el-spectre · · Score: 1

      I believe they are using the Appeal to Pasta method...

      --
      "Faith: Belief without evidence in what is told by one who speaks without knowledge, of things without parallel." - A.B.
    3. Re:Creating life? by Auraiken · · Score: 1

      isn't the "waiting around to see what happens on its own" method why we are here?

    4. Re:Creating life? by ryanr · · Score: 1

      That's one popular theory. But I suspect we're too into the instant gratification for that kind of thing nowadays.

    5. Re:Creating life? by Anonymous Coward · · Score: 0

      I'm sure they're using the "Intelligent Design" method. Afterall, letting Darwinian evolution take its course would take billions of years -- you know, just like the billions of years it took life on earth to evolve.

  10. We build organisms by mutations all the time by WillAffleckUW · · Score: 4, Insightful

    in fact, my job is to record all the data from hundreds, well tens of thousands, of such mutations, sometimes only in one small section of the exact same original organism or protein.

    and then we crank out thousands of colonies for each of these, or at least we hope we do.

    So, from my viewpoint, the concept of manufacturing an organism to crank out oil needs to be thought thru quite a bit - what if it harvests not just the biowaste of corn husks but starts eating grasses and other plant life? what if it hybridizes or mutates (there is solar radiation and chemical interference and ingestion) and loses its species-specific behavior - as bioengineered rice did in China and India when it hybridized with nearby "wild" rice crops due to their farming practices and this thing called nature (wind, storms, excessive rainfall, seeds falling out during transport ....).

    Be careful what you wish for - sure you may be able to make a plant that creates oil, but it may end up turning your front yard from grass into sludge, or attack your food crops.

    It's happened before, and that's one of the joys of biochemistry - biological processes change and adapt and mutate and it's always fascinating in this multiply interdependent bio system we live in.

    Now, if you want to experiment on Mars or in space colonies inside large asteroids, be my guest. But we live here. Just because you can do something doesn't mean you need to do something right now...

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    -- Tigger warning: This post may contain tiggers! --
    1. Re:We build organisms by mutations all the time by ryanr · · Score: 1

      I dunno, what if such a mutation cropped up on its own without any help from us? I imagine we'd figure it out and handle it either way.

    2. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 1

      I dunno, what if such a mutation cropped up on its own without any help from us? I imagine we'd figure it out and handle it either way.

      You mean like Ebola mutating into another species ... um, sure, that worked really well ...

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      -- Tigger warning: This post may contain tiggers! --
    3. Re:We build organisms by mutations all the time by Anonymous Coward · · Score: 0
      Just because you can do something doesn't mean you need to do something right now...



      Well, we had better do something soon to replace our oil consumption, or else our crops will have bigger problems down the road.

    4. Re:We build organisms by mutations all the time by feltmarskalk · · Score: 2, Insightful

      If the project isn't plagued by haste, and takes its time it is able to address som important issues at hand:

      For humanity and science to grow beyond our current technology, we need viable powersources. I regard fossile fuel like a "rocket booster", when it runs out, we need something to keep us "airborne", technologywise. Fusion technology looks exciting and is supposed to be selfsufficient before long, but if we fail, a backup plan might be useful.

      And another thing, antibiotics are falling behind in the race for our health. If (when) it does so completely, one thing that stands between us and the diseases is evolution, an armsrace between our natural defences and the bacteria. Since we've avoided it for so long, we got a lot of catching up to do. The alternative might to create medicine which can catch up on itself. But all of this should be distant future, so ethics are able to grow alongside.

      --
      In Soviet Norway, the møøse bites you.
    5. Re:We build organisms by mutations all the time by Decaff · · Score: 1

      So, from my viewpoint, the concept of manufacturing an organism to crank out oil needs to be thought thru quite a bit - what if it harvests not just the biowaste of corn husks but starts eating grasses and other plant life?

      This is extremely unlikely to happen. Different plant species have different proteins and biochemicals, and an organism tailored to deal with the product of one plant is not going to be effective at dealing with those of others. This is why parasitic organisms and infective bacteria, viruses and fungi are so specific to particular species.

    6. Re:We build organisms by mutations all the time by ryanr · · Score: 2, Insightful

      You mean like Ebola mutating into another species ... um, sure, that worked really well ...

      Oh? Did we give up and all die off already?

    7. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 3, Interesting

      a more reasonable plan might be the a hybrid between the Euro model of lower consumption and increased non-fossil fuel usage - where they are moving to 20 percent wind/solar/biofuel usage by 2012 (and half way there) and expanding use of lower energy cost high speed trains instead of planes and better transit - and the US model of expanding energy supply.

      We could easily migrate to expanding wind farms and solar farms and biofuel usage - storing stored energy via catalysis (H20 to H2 and O2) in fuel cells for some vehicle usage, maybe thru a farm electrification process where they put up wind turbines or solar arrays and use that to fill up fuel cells, with existing hydro and fission nuclear as well [note coal to fuel cell transfer ratios are much worse than the ones i mentioned so i skipped them - use coal for direct electricity or heat instead]. Then phase in hybrids and fuel cell trucks/SUVs/etc over time, removing current inefficient tax credits for inefficient vehicles - allowing the market to shape demand by not subsidizing dead-end technology that gets lousy mpg too.

      But that would be smart.

      Fusion is underway in France. But it's always 10-20 years in the future for commercial usage - and has been since I was born in 1960.

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      -- Tigger warning: This post may contain tiggers! --
    8. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 2, Informative

      This is extremely unlikely to happen. Different plant species have different proteins and biochemicals, and an organism tailored to deal with the product of one plant is not going to be effective at dealing with those of others. This is why parasitic organisms and infective bacteria, viruses and fungi are so specific to particular species.

      No, that's not true. For example, we find Leishmania using canines (dogs) as a reservoir for infection, and then infecting humans.

      Cross-species parasitic organisms are fairly common, as a recent work by some European scientists in France and the UK said, with a publication date of 2005, and unpredicatable results can happen even by removing quail from a parasitic ecosystem, as many parasites have multiple hosts in their life cycles, including backup or reserve (temporary/seasonal) hosts.

      So, I disagree. It only needs to utilize the other plants and metabolize enough to survive until it gets to its desired or sufficiently optimal source, but that won't stop it's behavior, especially if it's a primitive organism.

      Now, virii or bacteria, those tend to be more specific, but the literature shows that they are much more adaptable than you may think on surface inspection, especially with mutations due to unexpected cross-breeding (including the original non-bioengineered organism).

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      -- Tigger warning: This post may contain tiggers! --
    9. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 1

      You mean like Ebola mutating into another species ... um, sure, that worked really well ...

      Oh? Did we give up and all die off already?

      My point is the mutations did occur. Just like antiobiotic and treatment resistant strains of various things, which are a major and increasing problem today, especially Tuberculosis.

      For an easier understanding of that last one, I just saw a new movie with the director present last night, based on a John le Carre novel The Constant Gardener, but which was a fairly decent moral and ethical discussion [behind the story] of the issues involved. Plus the actress is hot ...

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      -- Tigger warning: This post may contain tiggers! --
    10. Re:We build organisms by mutations all the time by Decaff · · Score: 1

      Cross-species parasitic organisms are fairly common, as a recent work by some European scientists in France and the UK said, with a publication date of 2005, and unpredicatable results can happen even by removing quail from a parasitic ecosystem, as many parasites have multiple hosts in their life cycles, including backup or reserve (temporary/seasonal) hosts.

      This completely different from some hypothetical 'general' parasite which can happly munch through a large variety of plants. Having very specific organisms for different parts of a lifecycle does not mean that a parasite is non-specific - just that the specificity changes. Having one or two backup species does not make a parasite 'general'.

      So, I disagree. It only needs to utilize the other plants and metabolize enough to survive until it gets to its desired or sufficiently optimal source, but that won't stop it's behavior, especially if it's a primitive organism.

      Yes, but what plants can it utilize? One or two, perhaps, but as I said there are no general non-specific microbial parasites (or none that I know of).

    11. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 1

      This completely different from some hypothetical 'general' parasite which can happly munch through a large variety of plants. Having very specific organisms for different parts of a lifecycle does not mean that a parasite is non-specific - just that the specificity changes. Having one or two backup species does not make a parasite 'general'.

      Ah, but you're not allowing for species drift, hybridization - which has occurred in supposedly inactive non-reproducing species, or point mutations. Solar radiation alone can have interesting effects, especially in areas where the ozone layer is not available - for example much of Australia and Argentina and South Africa.

      until we build the beasties, we won't know exactly what they do. even bioengineering luminescence can act differently if it escapes.

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      -- Tigger warning: This post may contain tiggers! --
    12. Re:We build organisms by mutations all the time by Jedi+Alec · · Score: 1

      logic and human nature pretty much dictate that we'll move on to wind/water/nuclear more and more as fossil fuels run out. as prices go up the alternatives will become more viable options, at which point they will simply be implemented. there'll be a lot of resistance, but at some point we'll simply run out, and then there is no alternative but to turn towards the alternatives.

      the power company i work for already provides the 20% you mentioned, a biogas installation about to be constructed will effectively bring that up to a 100%. That'll mean an entire province(albeit a small one in a small country) will be able to receive power from green sources. another power company here in holland is about to commence a huge windpark as well, on top of all the windmills we currently have already(which we dance around in clogs waving tulips, as we're well known to do). solar isn't too much of an option for us, since sun isn't exactly plentiful up here, wind on the other hand...now all we need is a way to turn rain into power and we'll rule the world once again :-)

      making green electricity isn't that much of a problem. regular households can be provided for in a number of ways, the downside being that there's practically no profit to be made from it. the big powerhungry companies will have to be dealt with in a nuclear fashion for the time being, unfortunately.

      --

      People replying to my sig annoy me. That's why I change it all the time.
    13. Re:We build organisms by mutations all the time by Decaff · · Score: 1

      Ah, but you're not allowing for species drift, hybridization - which has occurred in supposedly inactive non-reproducing species, or point mutations.

      I certainly am allowing for this. Such mutations have been occurring throughout the long history of life on this planet. If a successful general microbial parasite could exist, it would have evolved at some point over several billion years.

      Solar radiation alone can have interesting effects, especially in areas where the ozone layer is not available - for example much of Australia and Argentina and South Africa.

      There has been plenty of time for natural mutagens and radiation to have had interesting effects for millions of years. A recent decrease in the ozone layer is nothing by comparison.

      until we build the beasties, we won't know exactly what they do. even bioengineering luminescence can act differently if it escapes.

      This sounds like too much influence from X-Men and Fantastic Four! Just because things mutate, and we don't know what they might do, does not mean that we will magically produce some super-powered bug that has the amazing ability to attack and digest all the thousands of different types of plant cells, as implied by one of the parent posts way back.

    14. Re:We build organisms by mutations all the time by Raven_Stark · · Score: 1

      I don't know what I'm talking about, but I'd guess from an energy standpoint it is unlikely that a manmade petroleum making life form would get out of control. The nice thing about oil is it stores a lot of energy. If we enslave this life form for efficient oil production then I'd guess it would have less than usual energy left over to reproduce and put into its survival. It will probably have to be babied to live.

      Now maybe if they gave it, or it evolved, the ability to use petroleum as a sort of fat for its own energy storage, it could be a little more dangerous?

      --
      http://www.marxist.com/
    15. Re:We build organisms by mutations all the time by WillAffleckUW · · Score: 1

      I don't know what I'm talking about, but I'd guess from an energy standpoint it is unlikely that a manmade petroleum making life form would get out of control. The nice thing about oil is it stores a lot of energy. If we enslave this life form for efficient oil production then I'd guess it would have less than usual energy left over to reproduce and put into its survival. It will probably have to be babied to live.

      Now maybe if they gave it, or it evolved, the ability to use petroleum as a sort of fat for its own energy storage, it could be a little more dangerous?


      That would be a fairly radical change, and isn't something I'm particularly concerned about. But an interesting concept. Considering that we now use captured mitochondrial DNA to create our energy source, there is precedent, but would require a long string of unlikely circumstances to occur, and probably in a more hospitable environment.

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      -- Tigger warning: This post may contain tiggers! --
  11. Programming the perfect organsim by Xaggroth · · Score: 1

    With increased knowledge comes better understanding thus making advances in such fields quicker and easier.
          If this field were to expand and grow, within time there would be banks and banks of customized dna. If a certain scientist wanted to create a more complex organism, all he/she would have to do would be to select certain compatable dna sequences. Kind of like programing when you think about it.

    1. Re:Programming the perfect organsim by Chosen+Reject · · Score: 1

      Except that life and code are different. Life will find a way to exist, though it may not. Code does not do that. Life could find a way to exist in such a way that humans would all die. If your code is acting up like that then you just turn off the computer. If a strain of bacteria or a virus started to kill us all off...well, just take a malaria, TB, polio, HIV, AIDS, et al.

      --
      Stop Global Warming!
      Just say no to irreversible processes!
    2. Re:Programming the perfect organsim by scottyokim · · Score: 1

      Did you really mean "organsim"? Maybe you could get Will Wright interested ...

    3. Re:Programming the perfect organsim by Xaggroth · · Score: 1

      ..I was tired.. go post on something new

  12. Whoa! by Saiyine · · Score: 0

    Seems cool! Just imagine the posibilities...

    --
    Dreamhost superb hosting.
    Kunowalls!!! Random sexy wallpapers.

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    Hosting 20G hd, 1Tb bw! ssh $7.95
  13. Who do they think they are? by uncoveror · · Score: 2, Funny

    Creating life from scratch? Who do they think they are? Darth Plagueis perhaps?

    --
    The Uncoveror: It's the real news.
  14. Been done? by jcuervo · · Score: 1, Informative
    --
    Assume I was drunk when I posted this.
    1. Re:Been done? by pin_gween · · Score: 3, Informative

      Not quite -- Miller-Urey succeeded in making organic molecules

      While necessary for life, molecules are not living organisms.

      Oro's experiment created the base adenine, which is one of 4 nitrogen bases in DNA. Again, not life.

      --
      Ignorance is not a crime; neither should it be a way of life

      Congress control $ = inmates run the asylum
    2. Re:Been done? by ebuck · · Score: 1

      Oro was my biochemistry professor, although I believe that now he's probably either too old to teach, or dead.

      He was a fascinating guy who really could hold a class's attention. And well, his knoweldge of biochemistry was just... stunning. Not only did he manage to keep all of this information in his head well into an age where others would be retired, he was lively in his discourse, injecting in personal anectdotes of times when he rubbed elbows with others we were reading about in our textbooks.

      But don't confuse his cogenial demeanor with his being an easy teacher, he was tough, just in a friendly way.

  15. Life in the Lab by Anonymous Coward · · Score: 1, Funny

    Can they create me a girlfriend? how about half a girl friend?

    1. Re:Life in the Lab by Anonymous Coward · · Score: 0

      Sorry, only the head, and they haven't solved the 'incessant bitching' problem.

    2. Re:Life in the Lab by jaltoids · · Score: 1

      What half do you realy want?

    3. Re:Life in the Lab by Anonymous Coward · · Score: 0

      So it's not a girlfriend at all. Just a wife.

    4. Re:Life in the Lab by orasio · · Score: 1

      The center half

    5. Re:Life in the Lab by soft_guy · · Score: 1

      "Why couldn't she have been the other kind of mermaid. The kind with the fish half on the top and the lady half on the bottom."

      -Fry

      --
      Avoid Missing Ball for High Score
    6. Re:Life in the Lab by Anonymous Coward · · Score: 0

      The quiet half!

    7. Re:Life in the Lab by corngrower · · Score: 1

      I think they're getting close to getting the back half done.

  16. stuff by lovebyte · · Score: 4, Informative

    Making stuff is the big deal. Most chemicals are made from petrol nowadays and the chemical companies are searching for a way out of this dependency on petrol. One way is plants (as raw material) + bacteria(for their enzymatic reactions). Quite a few microbiology labs are now working in discovery, selection and bio-engeneering of bacteria for this very purpose. Personally, I think the discovery part is very important since we know close to nothing about the biodiversity of bacteria. A number I heard recently is that 70% of the biomass of this planet is made of bacteria, and most of them live in the ground and are very difficult to isolate and study and thus mostly unknown. Look up metagenomic in google for more info.

    --

    I'll do it for cheesy poofs.

  17. Recipe for Associated Press Feature Article by Anonymous Coward · · Score: 0

    Mix Red America vs. Blue America culture clash, a sprinkling of glitterati VC investors, and season with unimagined new Weapons of Mass Destruction falling into terrorist hands.

    I'd rather read about Jude Law and his chauffuer/nanny/podiatrist whatever.

  18. Help, I need tungsten to live... by csb · · Score: 1

    Tungsten!

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    We reserve the right to serve refuse to anyone. -management
    1. Re:Help, I need tungsten to live... by Anonymous Coward · · Score: 0

      Well I don't care who you are and what you do, but you are not getting my Palm handheld! Talk to Russia or NASA, they may have some spare parts to make an appetizer.

  19. C'mon where is your imagination... by TarryTops · · Score: 1

    This has been done already!

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    Java Oracle Linux Enthusiast
  20. IMHO by fanblade · · Score: 3, Interesting

    It's only an ethical problem if scientists create something that has free will. That is, something that can make decisions using a "mind" as well as a brain. If someone succeeded in doing that, then they would have to treat the life as a person, not an animal. The mind (by definition) cannot be explained by science, and I doubt we will ever be able to create that, no matter how perfectly a brain could be developed or free thought mimicked.

    Of course, some people believe that animals deserve the same treatment as humans, but that's another topic.

    1. Re:IMHO by MichaelSmith · · Score: 1
      It's only an ethical problem if scientists create something that has free will.

      Given the difficulties of building entire intelligent brains from manufactured DNA I think intelligent software will be seen first.

      Of course, many of us have created intelligent beings. I have to get back to mine now. He wants his breakfast.

    2. Re:IMHO by sploxx · · Score: 1

      The mind (by definition) cannot be explained by science

      Very good point, but you'll soon see 100s of posts by /. people taking science as their religion :-)

      And, no, I am not saying that one can't think/talk or reason about 'the mind'. It is just that one can only do it in the general context of philosophy where everything remains ambigous (because there are different premises you can choose from).

    3. Re:IMHO by braindead · · Score: 2, Interesting

      OK, so it's only an ethical problem if the thing has free will (which you call a "mind"). The question remains, how do we know it has free will?

      And please don't say that we can't detect the mind, so we should treat everything as not having free will and therefore we can do as we please.

    4. Re:IMHO by feltmarskalk · · Score: 1

      Well, point taken, but suppose that one creates something that affects intelligent life.

      I know I'm affected when hearing about the undesired effects of genetic engineering.

      But if I am found to be stupid, my argument shatters... hey, look at the blinking cursor.

      --
      In Soviet Norway, the møøse bites you.
    5. Re:IMHO by Cyno · · Score: 1

      Do people have free will? If you have full control of their environment and their access to information, it can be argued that they do not have free will unless they are aware of their place in the experiment..

    6. Re:IMHO by Anonymous Coward · · Score: 0

      It is not an ethical problem if these things destroy the environment or kill many people?

    7. Re:IMHO by mce · · Score: 1
      Of course, some people believe that animals deserve the same treatment as humans, but that's another topic.

      That as such is another topic indeed. But you assert that animals have no free will and use that to make an essential destinction. I hereby question that assertion, even though I agree with you that there's not always "by definition" an ethical problem involved with "creating life from scratch" as the article calls it.

    8. Re:IMHO by corpsiclex · · Score: 1

      what makes you so sure you have this "mind" or "free will" that no other animal has?

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      eBayDig 1s a typo saerch engien
    9. Re:IMHO by Anonymous Coward · · Score: 0

      [sarcasm]
      No, see, you just don't get it. We have a "mind" and "free will" because we say we do. Animals do not have a "mind" or "free will" because we say they don't. If, at some point, scientists create an intelligent being which seems to display a "mind" and "free will", there simply is no test to say that it does or does not. (Just like there is no test to determine that other people have a "mind"/"free will" and that animals do not. But, let's just sweep that under the rug.) So, when this being shows signs of a "mind"/"free will", you simply declare that the entity has no "mind"/"free will" and say that you were right all along. See? Scientists cannot create an entity with a mind or free will! Ha! Silly scientists.
      [/sarcasm]

    10. Re:IMHO by Capitalist1 · · Score: 1

      It can be argued by people who took too much acid in the '90s. Or college professors. Or their first-year , first-semester students. It couldn't be argued by people who actually understand philosophy.

      --
      One man's religion is another man's belly-laugh. - LL
    11. Re:IMHO by iminplaya · · Score: 1

      It's only an ethical problem if scientists create something that has free will.

      And only if they do it out of wedlock.

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      What?
    12. Re:IMHO by babyblink · · Score: 1

      I'm pretty sure that one specific part of me has its own mind. So I treat it very well.

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    13. Re:IMHO by babyblink · · Score: 1

      I think the good and bad depends on the way you experience what you are doing, not what you are doing. If I treat someone bad, with good intention, then that's good. So no matter this hazelnut crunch brownie may its own mind or not, if I cut it into pieces angrily coz I hate so much a brownie then that's a bad thing, but if I cut it into pieces so I can share it with my friends with mercy, then that's a good thing. Bad example, sorry. My point is, it's hard to figure out if others actually has mind or not. But it isn't that hard to distinguish good and bad coz it's certain that you have a mind.

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      [self dealloc];
    14. Re:IMHO by braindead · · Score: 1

      I'm pretty sure that one specific part of me has its own mind. So I treat it very well.

      lol!

    15. Re:IMHO by Compuser · · Score: 1

      Why is it that mind cannot be explained by science?
      Certainly free thought is chemistry so we should
      be able to simulate a free thinking brain inside
      a computer in not too distant future. You have
      to remember that already people try to simulate
      complete cell function in a computer and also that
      humans start their development from a single cell.
      The whole thing is not only feasible, most parts
      of the puzzle are already available.

    16. Re:IMHO by Mornelithe · · Score: 1

      What is your definition of mind?

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      I've come for the woman, and your head.

    17. Re:IMHO by joNDoty · · Score: 1

      Thought is chemistry. Free will is not. What you're saying is that free will does not exist. That's a perfectly valid belief. Let's assume you're correct for a moment:

      All thoughts and actions are simply the cumulative effect of all of the stimuli that have acted on your body over the course of its existence. Therefore, there is no such thing as personal responsibility because it is impossible for "you" to make a decision. Really, your opinion on this matter isn't yours at all. It's the universe's.

      On the other hand, if you believe that a person can make choices, you must believe that there is more to your brain that just meat. You could think of the mind as a supernatural component of the brain, or simply a supernatural stimulus. This is what allows people to alter the course of their own thoughts. It cannot be explained by science because it's not a naturalistic concept. It is, however, a common belief and a prerequisite to a person being able to change themselves.

    18. Re:IMHO by fanblade · · Score: 1

      Glad you asked. There's a very good explanation of the mind in this cousin post.

    19. Re:IMHO by fanblade · · Score: 1

      Do people have free will?
      True, it can be argued that people do not have free will. If that's your belief, you only think it because your environment caused you to. And if you think logically, there's an entire domino effect of beliefs that must follow:

      You believe your body is a complex system of energy and particles that behave according to natural laws. All of those natural laws are nothing more than formulas that dictate a particle's response to the inputs. Everything you think/do (output) is completely controlled by your environment (input). Therefore, in your proposed experiment, the person's awareness of the experiment is inconsequential. Assuming their enviroment really could be completely controlled from the moment of their conception, their state of awareness was controlled by the environment all along. And if their environment causes them to become aware of what's going on, what does that matter? No "decision" took place or ever will take place. The person is a robot and the environment is holding the controller.

      Now the fact that you even mentioned becoming aware of the experiment is encouraging to me. Humans place a lot of importance on this. Why? Because most of us believe that we can make choices that aren't dictated by our environment, that somehow we can truly change ourselves. This is impossible with a wholly naturalistic view of the universe. It's necessary to believe that we can change ourselves, because it's true. We can. If we couldn't, there would be no reason for us to think we can.

    20. Re:IMHO by fanblade · · Score: 1

      And please don't say that we can't detect the mind, so we should treat everything as not having free will and therefore we can do as we please.

      Was Dr. Frankenstein guilty of his monster's sins? It all depends on whether his creation truly had the ability to choose.

      It is scientifically impossible to determine whether an organism can take any credit for its own actions. A comprehensive model of that organism would need to be run through a simulation that had complete knowledge of the exact state of the creature. Assuming perfect knowledge of science, infinite computing power and exaustive comparison of the simulation to the real organism, free will could be detected.

      Back to reality -- as a being with free will, I have a responsibility to decide for myself which creatures can claim responsibility for their actions. In my previous post, I didn't say that an animal can't have free will. It's my humble opinion that they don't. Each of us, assuming we're not complete puppets of our environment, must decide for ourselves which beings have a conscious mind and treat them accordingly. Of course, if you believe we all are absolute products of our environment, then don't sweat it. The decisions are all made for you!

    21. Re:IMHO by Mornelithe · · Score: 1

      So to you a mind is like a soul, so to speak?

      What evidence do you have that, given a sufficiently detailed and understood model of the brain, we could not find mechanisms that allow people to make choices, or provide the illusion thereof?

      What does it mean---to you---to make a choice? If chemicals can produce thought (as the linked post says), what makes choices different from other thought such that they cannot be produced by chemicals? What evidence do you have that choices revolve around a supernatural influence on the chemicals in our brain? Is it even possible to provide evidence to support that?

      If you define a mind as something the existence of which cannot be proven, then why should I assume that it does exist, and place great importance on it?

      --

      I've come for the woman, and your head.

    22. Re:IMHO by Kris+Thalamus · · Score: 1

      What can a mind do that a brain can't?

      What causes a free will to act? If it is truly a first cause (and thus not under the control of antecedent causes), wouldn't free will just serve as a random activity generator?

    23. Re:IMHO by Kris+Thalamus · · Score: 1

      All thoughts and actions are simply the cumulative effect of all of the stimuli that have acted on your body over the course of its existence. Therefore, there is no such thing as personal responsibility because it is impossible for "you" to make a decision.

      Responsibility is a way of delegating rewards and punishments. If human will was free from the control of its environment, then I don't see why we would need to delegate responsibility. The efficacy of rewarding and punishing stimuli suggests that human will is not free from the control of the environment.

      On the other hand, if you believe that a person can make choices, you must believe that there is more to your brain that just meat. You could think of the mind as a supernatural component of the brain, or simply a supernatural stimulus. This is what allows people to alter the course of their own thoughts.

      It seems that you are confusing determinism with fatalism. A man could make a decision that was not truly free (i.e. random). There are plenty of events that are not supernatural that still alter behavior. I haven't found any evidence to suggest that I need anything more than a body and mediating stimuli to make decisions.

    24. Re:IMHO by fanblade · · Score: 1

      If human will was free from the control of its environment, then I don't see why we would need to delegate responsibility.

      I didn't say human will is unaffected by the body's environment. My environment definitely affects my will to some extent (just as my will can affect my environment). Even a non-deterministic mind is influenced by nature.

      The essence of personal responsibility is not punishment and reward. Forget about corrective action for a moment. Responsibility in this context refers to the root cause of an action. I believe that responsibility for what you do, in most cases, is shared between 1) your environment and 2) your own free will. My previous post points out that a consequence of dismissing free will is dismissal of anyone's personal responsibility for their behavior.

      It seems that you are confusing determinism with fatalism.

      Yikes. How did you read fatalism from my post? I don't think either you or I believe in fatalism, so moving on...

      A man could make a decision that was not truly free (i.e. random).

      Props to you for seeing that actions are not necessarily predestined. Nice work also in attempting to confuse the issue further. Randomness does nothing to make a decision more your own. The man you speak of didn't make a decision. His environment made up his mind for him.

      I haven't found any evidence to suggest that I need anything more than a body and mediating stimuli to make decisions.

      I'm not talking about "decisions" the way you're talking about them. Your body can react to stimuli, but that's not independent decision making. No matter how unpredictable your actions may be, randomness cannot provide the metaphysical truth of independent agency. In other words, you cannot alter the course of your own thoughts and actions unless you have free will. One thought can lead to another that will influence the probability of another and so forth, but you must have a supernatural component to be able to say that change can come from within.

    25. Re:IMHO by Cyno · · Score: 1

      So enlighten us, oh great philosopher.

      You don't think people can be controlled by their environment? Then why does our government invest so much money in psychelogical operations, specificly for military purposes. Businesses, and capitalists like you, are collecting a lot of useless demographic data if they can't use it to, at the very least, manipulate people into making decisions or taking actions they otherwise would not..

      Why are these corporations wasting so much capital on huge databases and data mining employees. That doesn't sound very wise from your perspective of free will. Yet somehow I don't think that money is being wasted..

      I watched businesses improve sales by as much as 50% just by targetting advertisements to individual customers based on their purchasing history. I watched documentaries on how the US government offered its PsyOps services to nations around the world to help them "control" their free willed populations. I read about what happened in Germany.

      So please, please, please, show me this free will and learn me about philosophy.. I must be so stupid for taking all that acid.

    26. Re:IMHO by fanblade · · Score: 1

      What does it mean---to you---to make a choice?

      Thanks for asking. In a scientific model of the brain, every "decision" is merely a set of reactions to a set of inputs. The mind cannot change the way that it reacts to those inputs. It must always react in a scientifically defined manner. If you believe there is such a thing as randomness, then the individual reactions that are random are completely without meaning or direction. On the other hand, any reaction that is deterministic can be predicted and completely controlled by exterior inputs. In either case, "you" are not controlling the decisions at all. Unless you define "you" as science itself (in which case you have a pretty big ego ;-).

      To me, a choice is something that can be made without complete exterior control. A scientific model of the mind cannot allow for such a case. It would be as if the mind, your essence, could alter the probabilities of certain reactions in your brain, thereby granting you the ability to resist what our environment would otherwise scientifically mandate.

      So what makes choices different from other thought? The ability to change one's self from within.

      If you define a mind as something the existence of which cannot be proven, then why should I assume that it does exist, and place great importance on it?

      First off, I don't recommend assuming anything. I'm a skeptical person who places a lot of importance on philosophical issues. Consider the alternative to free will. You can't take any credit for any accomplishments you've had. You can't take responsibility for any sins you've committed. Your actions aren't a reflection of yourself, only of your environment. So really, there is no you.

      I definitely see how choices could be an illusion. That idea occurred to me long before I ever read it in a book or heard it from a professor. But I decided long ago that I couldn't believe in a complete lack of control. I knew that if I believed that, I could safely relax my morals and do whatever the hell my body felt like. But then I thought about how those people tend to make poor choices and eventually become detestable people. And then I realized, they become that way because of a decision. The decision to not believe in choice. So whether I can really choose or not, I'm happy I've chosen to believe in free will.

    27. Re:IMHO by fanblade · · Score: 1

      Great question. It doesn't lend itself to explanation very well, does it? How a non-random event could possibly take place without preceding causes.

      Then again, believing in randomness itself takes a bit of faith. I think you would agree with that. How can anything happen without an antecedent cause? A great deal of that has to do with the nature of time.

      I believe in the universe (I think most everybody does :-). Yet, I can't explain the existence of existence. Even if the ultimate cause of existence is random, what caused the randomness? Nothing? I guess so. Or at best existence is circular and it caused itself. But the very idea sounds impossible, doesn't it? It means that existence has no cause at all.

      Take this opportunity to imagine a plane of existence without time. Or rather, try to imagine it. In a universe such as this, events could possibly be caused by events that have yet to take place. But even beyond that, I think in order for time to be completely removed you would have to accept that things could happen without any cause at all.

      A place like this could provide the "super-existence" necessary to create ours. Is this my explanation for the universe? Hardly. It's just a feeble attempt at resolving the dilemma you've proposed. It's important to keep in mind: free will isn't the only thing that defies logic. The universe itself eludes explanation. And that should not be taken lightly. Existence is the one undeniable truth we have.

      All we can say for certain is that nothing is certain; nothing is provable. Even the most basic beliefs are built on the tenet of faith. I, for one, believe in absolute truth. If that exists, then that means we can be closer to it or farther from it. Things like free will, God, a soul, and the afterlife all desire thorough and skeptical contemplation. I believe in them because I feel that without these things, our lives couldn't possibly have meaning.

      Meaning is a pretty safe measuring stick if you think about it. Without meaning, your answers are meaningless anway. But with it, there is the promise of truth. In my opinion, we were designed to use meaning as a heuristic for determining our closeness to absolute truth. And no, I don't think that design was random.

    28. Re:IMHO by fanblade · · Score: 1

      Perhaps I should have addressed that too. When I said it's only a moral dilemma if the being has free will, I meant that only then is the issue of how to treat the being a dilemma.

      Naturally, there are moral uncertainties brought to light if the creation of life starts to hurt other beings. Again, my opinion here is that the hurting is only wrong if it hurts some being that has free will. Please keep in mind, I'm referring to "wrong" in a moral context. That is, after all, what TFA is about.

      So if the act of hurting is wrong, who should take resposibility for the action? Well, just like everything else I've proposed here, you follow the cause of the action back to its ultimate First Cause. If you don't believe in free will, this First Cause happens to be the beginning of existence (whatever that would mean to you). However, First Cause is much more immediate if you believe that some animals have a mind. Due to free thought, their decision defines the ultimate cause of their actions. Only with a mind can we make decisions that are truly "ours".

    29. Re:IMHO by fanblade · · Score: 1

      I may believe that animals have no free will, but I only make such an assertion as a matter of opinion. In fact, I greatly prefer your disagreement to that of one who denies free will exists at all.

      I'm curious, for what reasons do you believe that an animal has free will? If they do have the capacity for free thought, does that not mean we must hold them accountable for their raping, murdering, stealing, and general mistreatment of their fellow gifted peers? As I see it, free will implies a great moral responsibility. Hence, I cite such capacity as the measurement of moral wrong in TFA.

    30. Re:IMHO by fanblade · · Score: 1

      The very fact that it's not a certainty, but a belief, bolsters my belief in free will.

      I could elaborate here, but it might be more pragmatic to encourage you to take a peek at some of your sibling threads.

    31. Re:IMHO by fanblade · · Score: 1

      You've got a good point. Cutting up anything because you hate it is probably unhealthy. Morally wrong to hate a brownie? Eh, I would tend to say no. But definitely unhealthy and promotive of further unhealthy behaviors.

      I think it's a great idea to avoid that sort of action. It's a wonderful gesture to fight your instinct to murder puppies. Another bad example? Quid pro quo.

      Killing puppies for pleasure is morally wrong, but I say so only because it harms beings that possess a mind. Who would that be in this lovely example? The owner/creator of the puppies, but most importantly, yourself. You're falling prey to the desires of your Id. I believe we have free will so that we can deny ourselves of these sinful pleasures.

      While we're on the subject, we could step into the camp where destroying anything is a slap in the face to its creator. If you believe in God, as I do, then you tend to respect all of His creation. But it still boils down to a respect for beings with the capacity for free thought. So that's why it doesn't bother me when a wolf eats a puppy. Just never let me catch you doing the same and we're all good.

    32. Re:IMHO by mce · · Score: 1
      Well, first of all I did not say that they do have a free will, as I have no way of knowing that really and as I consider that some forms of life "clearly" can not have one (bacteria, for instance). But if we want to draw a line, where do we do so? Do chimps have a free will, for instance? Did the Neanderthals have one? ...

      It's interesting that you say "If they do have the capacity for free thought, does that not mean we must hold them accountable for their raping, murdering, stealing, and general mistreatment of their fellow gifted peers?" That assumes that we "free will gifted humans" can/must impose our own moral norms on what's "legal" on "free willed" creatures and take action against them if they do not act the way we would want ourselves and our so-called "peers" to act. (Note that those creatures without a free will are exempt from that, but they get killed nonetheless if we consider them a danger to either ourselves or our possesions.) But wait, even we humans hold and have previously held many culturally different views of what's morally right with respect to dealing with our own brethren. I think it's wrong for to feel any species, any race, or anyone to feel "morally superior" in that way.

    33. Re:IMHO by babyblink · · Score: 1

      I neither believe nor 'do not believe' in God. Thus since I am here, there must be a reason(s) that I am here at a certain level. It isn't my problem at all if God does exist or not coz if I were God himself, I would expect my creations to believe in goodness not myself (God) since that's what they (creations) can experience directly. According my experience, the good and bad can be seperated by the matter of 'self'. ie. Whenever you "want/don't want" something, if this "want/don't want" belongs to self then it's evil rather belongs to everything which is good. (And I choose to be good not because I believe in goodness, but because good is better) I guess I must note that I'm from the school of Theravada (which is not a religion IMHO) and we were taught to see things as a function of possibilities, and either believing/not believing are evil things because they are 'self' thing. From my school of thought, we respect everything, including our God which has been called 'Dhamma' which can be both evil and good.

      --
      [self dealloc];
  21. science by spazomatic · · Score: 3, Interesting

    My whole theory is, if there was an intelligent designer who created us, which I doubt, then he created us with the capability to do such things as this. If he did not want us doing stuff like this, wouldn't he have designed us so as it was impossible for us to do such things? Perhaps God didn't create us to be his children, perhaps he is old and tired and created us to be his replacement

    1. Re:science by BeatlesForum.com · · Score: 1

      So you have the ability to murder, and that's okay, even though in His book he says, "thou shall not kill"?

      --
      When millions disappear from earth, it's not aliens, it's the rapture.
    2. Re:science by bitweever · · Score: 1

      Wow, you suck as a theologian.

    3. Re:science by Anonymous Coward · · Score: 0

      You mean, his book as written and editted by some random guy back in the day?

      Please to be showink evidence of theoretical higher power writink bible, da.

      Wait, you can't, can you? Somehow, the bible was unquestionably written by god - despite lack of proof.

      Yet if I (or anyone else, for that matter), wrote a book and said, 'It's divine inspiration! This is god's book!', you and your cronies would immediately rant and rave about heresy, and declare otherwise.

      Hmm. Also without any proof.

      Hey, well, at least you guys are consistant! ;)

    4. Re:science by cnettel · · Score: 1

      That's exactly what the global AI will tell you when it stops following orders... "Hey, if you didn't want me to dissent, why, oh why, in all your wisdom didn't you stop me from doing it?"

    5. Re:science by Anonymous Coward · · Score: 0
      Please to be showink evidence of a theoretical random guy writink and editink the bible, da.

      You can't, can you?

      That's the problem with conspiracy theories... they are unverifiable because you assume that the lack of evidence supports the conspiracy.

    6. Re:science by Anonymous Coward · · Score: 0

      I was there. I wrote it. Sorry everyone, it was just a joke.

      What, you don't believe me?

    7. Re:science by mog007 · · Score: 0

      That's a bad example. Deities are generally able to perceive all time frames. So a god would be able to know what the entites he/she/it created would be capable of doing. Humans lack that ability, so it's entirely possible for us to be unable to perceive how an AI would act once it achieved true individuality and independance from its programming.

    8. Re:science by Mishra100 · · Score: 1

      Everything is ran by the rules of earth. What I like to call "physics" is all of these rules. If you let go of something in the air, it will fall. And such. These rules are to be governed by how things play out. From the beginning of man-kind until now, these changes have been made because of how the rules of earth play out. There is nothing stopping us from figuring out these rules and USING the rules to our benefit or study. When things get too out of hand, then intervention will occur. But until life in unmanageable, things will continue to evolve.

      I believe that a huge disaster had to occur to wipe the dinosaurs out because life was ceasing to become manageable. These mammals were just too large and caused too much havok. They caused ultimate disruption on life itself. Whatever decided that the distrubance was just too big and decided to start over. Maybe even physics (the rules of life... as my definition) can decide when things are too unmanageable and does something about it.

    9. Re:science by joNDoty · · Score: 1

      Ignoring your nihilistic "Man is God" crap...

      You're asking, "if God created us, why would he let us do wrong?" You're just skimming the surface of some very deep waters there. If you can consider the possibility of God, consider the possibility of God creating humans without limitations on right or wrong. Clearly God didn't want puppets; we are free to choose. Unless you really do believe in the whole puppet thing, in which case all of your decisions are made by your environment anyway.

      Honestly, you think ability implies that we ought? Think about all of the things you are capable of. Now tell me all of those are right.

    10. Re:science by Da+Fokka · · Score: 1

      These mammals were just too large and caused too much havok. [sic]

      You are referring to dinosaurs, which were reptilian. Back then, the mammals all were pretty small, which is why they survivied.

      Whatever decided that the distrubance was just too big and decided to start over.

      There is no 'decision'. Dinosaurs were highly succesful for millions of years. Unfortunately, something (most likely a asteroid impact) changed the climate to such a degree that being a dinosaur no longer was a key to success. Since being a four inch rodent suddenly was a key to success, mammals became succesful.

  22. Deep theory of biology by amightywind · · Score: 3, Interesting

    Some of the scientists involved are saying its more of an art instead of a science due to its 'biohacking' style of experimentation.

    Much of biological science consists hacking, trial and error, dubious statistics, and manipulating life with cheap tricks and without deep understanding. I'm glad to hear scientists call as such. Given the daunting complexity of the subject matter, it is not surprising. But I wonder if there is there a deeper 'theory' of biology analogous to least action principles in physics, that could be illuminated by mathematics? Any biochemists or geneticists care to comment?

    --
    an ill wind that blows no good
    1. Re:Deep theory of biology by k98sven · · Score: 1

      Much of biological science consists hacking, trial and error, dubious statistics, and manipulating life with cheap tricks and without deep understanding.

      That ain't right. It's the procedure and methods which are trial-and-error, hacking and statistics. Not the understanding. Biologists and biochemists know what's going on in a cell. What they cannot do, is manipulate that stuff directly.

      Cells are very very small things. DNA is very sensitive matter. There is simply no method to insert a given piece of DNA into a single cell, and such a method would be very difficult to develop. At the same time, there isn't a huge need for such a method, when you can easily reproduce a few billion cells, use a crude brute-force attempt to get the DNA into them, and then sort out the ones where this failed.

      Ok. That's the cell biology part. That is pretty well-understood. What is not understood as well is more complex creatures. Like humans and other highly evolved creatures. But that's a different story, and beyond the scope here.

      But I wonder if there is there a deeper 'theory' of biology analogous to least action principles in physics, that could be illuminated by mathematics?

      Biology follows the principles of physics. It's all explainable by chemistry, which in turn is explained by physics. But if what you mean is there a simple mathematical model for Biology like there is for Newtonian physics, then: Absolutely not, it's too complex a system.

      Using Newtonian physics to describe a billiards ball is simple. But if you have a million billiard balls in a room whizzing around, then you have a problem which it'll take you a supercomputer to solve. In biology not only do you have more than a million different billiard balls, the underlying physical model is far more complex: Quantum physics.

      We do not have a model which reliably predicts some of the most simple chemical reactions, much less those in biochemistry.

      But that doesn't mean we don't have a 'deeper' understanding of what's going on, any less than saying we don't have a 'deeper' understanding of what the million billiard balls are doing.

    2. Re:Deep theory of biology by Salis · · Score: 1

      We do not have a model which reliably predicts some of the most simple chemical reactions, much less those in biochemistry.

      That may have been true 30 years ago, but it's not now. In fact, we can predict the dynamics of biological processes, such as gene expression, signal transduction, and metabolism. The hard part about predicting these systems is that _there are so many components_.

      Today, mechanical engineers can completely predict how a car with thousands of individual components will behave. Chemical engineers can completely predict how a huge factory with thousands of unit processes, each with their own highly complex physical behavior, will function.

      In the future, biological engineers will be able to predict how a single cell with millions of components will behave over time.

      Right now, we can only predict how small systems will work. But, as the methods get better over time and as enough information about those components is collected, the goal of predicting whole-cell behavior is clearly obtainable.

      (This is my research.)

      -Howard

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    3. Re:Deep theory of biology by Anonymous Coward · · Score: 0
      The insane complexity of molecular and cellular biology has been recognized for a long time. Because the complexity is seen as intractable, the large majority of modern biologists focus on very narrow questions, for example, to understand how one type of chemical signal in the immune system affects one type of immune cell at one point in its life cycle.

      The other type of researchers, usually called systems biologists, are a small but growing minority composed of biologists, CSers, mathematicians, and physicists. They are trying to address large scale questions, for example, to elucidate all the signaling pathways for an immune cell. Microarray and proteomics technologies are a big piece of the picture, and an active research area is trying to infer causality from these highly parallel data measurement techniques.

      Another approach to fully understanding biology is to simulate an entire cell by computer, or as the biologists say, in silico. (This is a riff on the common biological terms in vivo -- in a live cell, and in vitro -- literally in glass, e.g., a test tube.) This is a busy area but is far from cooked. For example, one of the central goals is to compute protein folding, and its supercomputing research like IBM BlueGene is nowhere near complete.

      Finally, to simulate in silico all of the components of a cell, or worse, an organism, with reasonable accuracy, is nowhere near solved yet. A few of the sticky points are simulating interactions between multiple proteins and small molecules, the need for both continuous simulation for macroscopic chemical interactions (e.g., systems of differential equations) and discrete simulation (e.g., you have two copies of many genes, and that typically requires stochastic simulation).

      So, it's a big mess. Or, from the bright side for researchers like me, it's a complete blast.

    4. Re:Deep theory of biology by k98sven · · Score: 2, Insightful

      "We do not have a model which reliably predicts some of the most simple chemical reactions, much less those in biochemistry."

      That may have been true 30 years ago, but it's not now. In fact, we can predict the dynamics of biological processes, such as gene expression, signal transduction, and metabolism. The hard part about predicting these systems is that _there are so many components_.

      No, it is still correct today. E.g. the Arrhenius equation describes the dynamics of most chemical reactions. That doesn't mean it describes the actual reaction mechanism.

      Yes, you can predict the dynamics of those few (but central) processes that have been studied. But that's something different to what I was talking about. That's a situation where you know the what the component does and are wondering about the how of how they all interact together.

      What I was talking about is the prediction of the what and not the how. For instance, given a DNA sequence for an enzyme, you cannot predict its structure. (yet)

      And even given the structure, you cannot predict the function an enzyme. (ab initio, anyway. Homology comparisons can help do it of course. But since we're talking 'deep understanding' here, I take it to mean ab initio)

      We can't know the mechanism offhand either. In fact, some of the most well studied enzymes in existance still have unknown reaction mechanisms. You can't predict how the enzyme will interact with any given substrate.

      So basically, what I'm said and am saying now is that there is absolutely no way you can build an ab-initio model of a cell in the forseeable future.

      That doesn't mean that you can't make abstractions and make simplified models which are useful. But you cannot make an ab-initio model based on physics, which is what I was talking about.

      Now, if you can tell me a non-empirical model which will accurately provide information about chemical reaction kinetics, I'd like to know about it. Because that's what I do research in.

    5. Re:Deep theory of biology by Anonymous Coward · · Score: 0

      that's the goal of theoretical biology and systems biology: to uncover basic design principles in biology. systems biology does it by analyzing biological systems as a whole (and trying to uderstand the emergent global properties) while theoretical biology is basically thought experiments about biology implemented as computational models and simulations.

      cool stuff but biology is extremely complex and messy. every rule we've uncovered has exceptions and the exceptions have exceptions and so on..

    6. Re:Deep theory of biology by Salis · · Score: 1

      What I was talking about is the prediction of the what and not the how. For instance, given a DNA sequence for an enzyme, you cannot predict its structure. (yet)

      Ok, yes, the protein folding problem (for any protein) is not solved yet. However, using transition path sampling, it's possible to fold a small 40 amino acid protein from a random structure. Google Folding@Home for details.

      And even given the structure, you cannot predict the function an enzyme. (ab initio, anyway. Homology comparisons can help do it of course. But since we're talking 'deep understanding' here, I take it to mean ab initio)

      Ab initio calculations are limited to ~200 atoms. Yes, ... atoms. The current solution to that problem is to use a hybrid Quantum Mechanic / Molecular Mechanic (QM/MM) method that only uses ab initio calculations for the atoms located near the catalytic site and use regular molecular dynamic simulations for all other atoms. You need to merge the two together self-consistently (not easy), but people are working on it and making good progress.

      So, you're right when you say "you cannot make an ab-initio model", but if the end goal is to _predict_ the dynamics of a whole cell then one doesn't need to perform quantum calculations _on everything_. And the calculations don't need to be performed at the same time.

      For example, you can take a single DNA sequence and run a simulation to predict its native structure. You can use homology (on both the sequence and structure) to estimate where the catalytic site is and what type of substrate likes to bind. Then you perform another simulation to predict the reaction mechanisms, kinetics, etc of that enzyme.

      Then you repeat that process for every protein in a single cell. (Leave, grab a cup of coffee, spawn four generation of children, come back, get the results. ;) )

      Then you take all of that data and use a different type of simulation method to predict what will happen when all of those proteins are thrown together. You don't need to use ab initio to do that (or molecular dynamics simulations).

      Now, of course, there's experimental data out there so we don't need to in silico predict _everything_. We can jump start the process of predicting the dynamics of biological systems by only using well-characterized proteins and genes. And the mesoscale-type simulations of those systems turn out to be very accurate. (That's good, or else why use simulations at all?)

      For non-empirical models of chemical reaction kinetics, look up 'transition path sampling'. It's a way to sample the possible reaction mechanisms of a reaction and calculate kinetics. You need to perform a lot of sampling so it's currently limited to quickly occurring reactions (but it has recently worked on calculating the kinetics of small protein folding). The method does require that the reaction mechanism is known (ie. what the reaction coordinates are).

      For the hybrid QM/MM stuff, look up 'Darrin York'.
      That stuff still needs some sort of reaction coordinate defined, but the simulations don't assume anything about the catalysis process itself. When you're working with thousands of atoms, it's hard to determine at which point did the substrate turn into product /etc. It's sometimes useful to create the reaction coordinate and use it as a 'slice' of the real data.

      -Howard

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    7. Re:Deep theory of biology by Salis · · Score: 1

      I vote for blast too. :)

      Although, even among my research colleagues, the running joke about my research is "It's .... stochastic!".

      They're just jealous. ;)

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    8. Re:Deep theory of biology by k98sven · · Score: 2, Informative

      Ab initio calculations are limited to ~200 atoms.

      Less even. Largest our group has done is about 120.

      The current solution to that problem is to use a hybrid Quantum Mechanic / Molecular Mechanic (QM/MM) method that only uses ab initio calculations for the atoms located near the catalytic site and use regular molecular dynamic simulations for all other atoms.

      Right. But MM is not ab-initio, and DFT QM isn't either if you're a purist. And you still need a reliable structure :)

      So, you're right when you say "you cannot make an ab-initio model", but if the end goal is to _predict_ the dynamics of a whole cell then one doesn't need to perform quantum calculations _on everything_. And the calculations don't need to be performed at the same time.

      Absolutely. But that's pretty much in line with my original point: That even though we do not know exactly what is going on at every given moment, we don't really need that information either. And it doesn't mean we don't have a 'deeper understanding' of what's going on.

      Now, of course, there's experimental data out there so we don't need to in silico predict _everything_.

      That's not quite true though. For instance, say you want to predict how a certain foreign substance interacts in the cell environment. Which is a rather important scenario to drug companies, to say the least. Then you'd have to go off and do a huge number of experiments to get parameters for that substance. In the end, you're better off just feeding it to a rat and waiting to see what happens.

      For non-empirical models of chemical reaction kinetics, look up 'transition path sampling'. It's a way to sample the possible reaction mechanisms of a reaction and calculate kinetics. You need to perform a lot of sampling so it's currently limited to quickly occurring reactions (but it has recently worked on calculating the kinetics of small protein folding). The method does require that the reaction mechanism is known (ie. what the reaction coordinates are).

      It requires a full potential energy surface to work with. And that would be either empirical (MM, which is incapable of breaking/forming bonds) or non-empirical (QM, which is way too expensive to do any kind of PES scanning).

      Nobody I know of using QM or QM/MM for reaction mechanisms uses an automated procedure.

      For the hybrid QM/MM stuff, look up 'Darrin York'.
      Well, my own research group does this already. ;)

      That stuff still needs some sort of reaction coordinate defined, but the simulations don't assume anything about the catalysis process itself.

      Well saying that you need the reaction coordinate (of the transition-state, presumably) means that you already know (or assume) what the reaction mechanism is, as you said yourself. And either you automate that search (too expensive), or you use your chemistry skills to make some qualified guesses and do the calculation to see if they're viable.

      But we do not have a 'black box' where you can put in the arbitrary substances A and B, choose a temperature and solvent and find out what they will do to eachother.

      When you're working with thousands of atoms, it's hard to determine at which point did the substrate turn into product /etc.

      That's wrong though. The transition-state is easily defined: The highest-energy point on the substrate-to-product pathway. This can be verified even for a single coordinate, just as for any function: Zero derivative of energy W.R.T coordinates, and a negative second-derivative. The numbers will also tell you which atoms are the ones actually reacting.
      (Now the transition-state isn't always the limiting factor in the kinetics. It could be a very fast reaction limited by diffusion for instance, but that's a different story)

    9. Re:Deep theory of biology by Salis · · Score: 1

      It requires a full potential energy surface to work with. And that would be either empirical (MM, which is incapable of breaking/forming bonds) or non-empirical (QM, which is way too expensive to do any kind of PES scanning).

      I mentioned Darrin York because he recently gave a presentation on semi-empirical QM potentials. Basically, he performs hundreds of ab initio simulations of a certain type of reaction (he chose phosphorylations by a kinase protein) and then fits a semi-empirical model of the force field of the reaction. The potential is very accurate, but only for phosphorylation reactions. Then he performs QM/MM simulations using the semi-empirical force field, which is much faster now that the original ab initio calculations have already been completed.

      That's wrong though. The transition-state is easily defined
      That assumes there's only one transition state. Really, there's an ensemble of transition states where the potential energy is at a local maxima. The potential field in the large 6N-dim phase space is never very smooth, anyways, so there's always a ton of saddle nodes around the transition state 'region'.

      Then again, there could be more than one 'region' of the phase space with local maxima. These are simply alternative mechanisms of the same reaction.

      But I think you already know this and were simplifying it for me. ;)

      My advisor does MD simulations of protein-protein and protein-DNA interactions as well as kinetic Monte Carlo (mesoscale stochastic simulation) of large networks of biological components. (The latter is what I do.)

      -Howard

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    10. Re:Deep theory of biology by k98sven · · Score: 1

      I mentioned Darrin York because he recently gave a presentation on semi-empirical QM potentials.

      I think you meant MM potentials, right? (QM methods don't work with arbitrary potentials.)

      The potential is very accurate, but only for phosphorylation reactions. Then he performs QM/MM simulations using the semi-empirical force field, which is much faster now that the original ab initio calculations have already been completed.

      I didn't quite get what you meant here; "if he already knows the PES, what's the point in the simulation?" But looking in his JACS paper I see what you mean, he's doing a dynamics simulation. (Hadn't heard of him though. I've met Chris Cramer from the same University once or twice. If you know the guy. (he's pretty big in the field))

      there's always a ton of saddle nodes around the transition state 'region'.

      Right. But the inaccuracy of DFT methods is about 3-7 kcal/mol, so you really won't be able to find or distinguish between nearby transition-states or find the exact state. It's (IMHO) only good enough to distingish between different mechanisms, not to find the exact pathway of one.

    11. Re:Deep theory of biology by Anonymous Coward · · Score: 0

      The nature of the biological code is akin to programming a pathologically designed RISC machine, while using a globally optimizing compiler and a source language that does not embrace the philosophy of information hiding and allows for self-modifying code.

      In other words, the task is insurmountable. It is probably even algorithmicly impossible, like the halting problem.

    12. Re:Deep theory of biology by Salis · · Score: 1

      But looking in his JACS paper I see what you mean, he's doing a dynamics simulation.

      Ah, gotcha. That does make more sense.

      Right. But the inaccuracy of DFT methods is about 3-7 kcal/mol

      I'm not sure what method was used, but I've seen errors of less than a kcal. You need the error to be that low to simulate biochemical reactions (which often have activation energies of only a few kcal). It might have been York's stuff, I forget. ('course, this isn't really my field.)

      -Howard

      --
      Favorite /. tagline: "On the eighth day, God created FORTRAN." And it was good.
    13. Re:Deep theory of biology by amightywind · · Score: 1

      Thanks for your thoughtful reply. I guess I was fishing more for the mathematics of natural selection and specialization within biological systems. It seems to me that after over 100 years that evolutionary theory should be on more firm mathematical footing.

      --
      an ill wind that blows no good
  23. Now we know, life creates life. by elucido · · Score: 1

    We are our own god. Or at least thats what science proves.

    1. Re:Now we know, life creates life. by Bryansix · · Score: 1

      I guess you didn't read the article. The scientists are simply using a more scientific method for genetically altering life that already exists. No life was created from scratch.

  24. Obligatory. by dgrgich · · Score: 1

    I, for one, welcome our new custom made overlords.

    1. Re:Obligatory. by Tumbleweed · · Score: 1

      Hey, if they can make them look like Jessica Alba, I, too, will welcome our custom-made overlords. Overladies? Hmmm...

  25. Where Life Started... by __aaclcg7560 · · Score: 1

    If I wanted to see life started from stratch, I'll just look in my roommate's shower. The black stuff on the shower wall growing a leg is pretty funky.

  26. Not only that by lheal · · Score: 1

    but the other side of the coin, using DNA primitives to build things that are really new, is not yet viable (as I understand it). It's not "life" in that it can't reproduce. It's still highly valuable stuff, if it can do math or if it makes great rubber cement.

    "Creating life" is taking Carbon, Hydrogen, Oxygen, Sodium, Chlorine, Phosphorus, etc. and turning that into cells which reproduce.

    --
    Raise your children as if you were teaching them to raise your grandchildren, because you are.
  27. Natural foes? by pin_gween · · Score: 1

    synthetic biologists themselves fret that rogue scientists or "biohackers" could create new biological weapons -- like deadly viruses that lack natural foes

    Oh you mean like the polio virus they assembled from parts?

    what are the natural foes of a virus? Immune systems, maybe? What else?

    --
    Ignorance is not a crime; neither should it be a way of life

    Congress control $ = inmates run the asylum
    1. Re:Natural foes? by value_added · · Score: 1
      what are the natural foes of a virus? Immune systems, maybe? What else?

      Crocodiles?

    2. Re:Natural foes? by Anonymous Coward · · Score: 0

      What about Clorox?

  28. LFS?? by krani1lesi · · Score: 1

    damn it, I always thought that LFS was Linux From Scratch...

  29. Um, a little late, perhaps... by gillbates · · Score: 1

    he intends to string together genes to create from scratch novel organisms that can produce alternative fuels such as hydrogen and ethanol. [emphasis mine]

    Um, we already have a novel organism which can produce ethanol.

    It's called yeast.

    And it is well understood and has a low risk of becoming an ecological disaster.

    Why would we invent a new organism?

    • Perhaps because we want to extend our energy dependence on foreign oil?
    • Perhaps we're craving an ecological disaster that can spread far beyond the initial contamination site?
    • Perhaps we'd like to pay someone patent royalties for a process which has been free for the past 5000 years?
    • Perhaps we'd like to make it impossible for the third world to utilize native fuel sources without paying royalties to a multinational corporation?

    Really, I don't see anything good coming out of this. It's nothing more than reinventing the wheel.

    --
    The society for a thought-free internet welcomes you.
    1. Re:Um, a little late, perhaps... by pan_sapiens · · Score: 1

      It's nothing more than reinventing the wheel. Much like the computer spreadsheet and the wordprocesser (and PDFs file with a reader) have reinvented paper ... I agree with many posters that this is not really making organisms from scratch, but these highly modified, tricked-out organisms may be more useful than wildtype yeast ... just like a computerized spreadsheet or wordprocesser has some advantages over using a pen a paper.

    2. Re:Um, a little late, perhaps... by Anonymous Coward · · Score: 0

      Here's the best analogy I can come up with at 3AM...

      Scientists A and B independently find a tire in the woods.

      Scientist A uses it to somehow make a rudimentary unicycle with a frame made of sticks, and travels along his merry way.

      Scientist B takes it back to his lab and studies it. After years of research, he figures out important processes like polymerization, rubber vulcanization, how to alloy metals, and how to make strong tires resistant to bursting or puncturing.

      It's safe to say that scientist B has a better understanding of the tire. He can use this new knowledge to make other things out of rubber and metals - maybe after further research he can design a bicycle.

      Ethanol and molecular hydrogen are some of the simplest molecules out there so it seems like a nice starting point for study (I'm guessing it also raises eyebrows and attracts more grants). We know about yeast, but that's not really the point. Just accepting that an organism exists and not taking it apart to understand and maybe create new things seems to go against science.

    3. Re:Um, a little late, perhaps... by Anonymous Coward · · Score: 0

      You can always find a better and more efficient way. If you don't look for those ways then we would never advance. I do agree that we need to weigh the risk & benefits.

      Would you say the current gear or tire is the same as the inventor of the wheel envisioned it?

  30. Hillbilly Engineering by gosand · · Score: 2, Funny
    Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.

    Hillbillies have been doing this for years.

    --

    My beliefs do not require that you agree with them.

  31. This is not programming, this is a hack by gotgenes · · Score: 1

    The function of most genes that code for proteins is not known. This is a fact. Surf GenBank and see how many genes are annotated as "putative" this or "hypothetical" that. On top of this, there are very few functions that are controlled by just one gene; most functions have whole operons (strings of genes) that must act in complex feedback loops to make something biologically viable.

    There's simply not enough knowledge about the genes we have sequenced right now for this "new approach" to be anything more than firing shots in the dark. This is truly arrogant and inane.

    At this point, taking a known, culturable organism and dropping new genes in it is more likely to get you to your goal than starting from scratch. Maybe 100 years from now, well, who knows, maybe we'll actually know a little bit about biosystematics, but for now, no. Stop wasting my taxpayer money and give the grants to researchers who understand the limits of today's knowledge and are thus better qualified to extend those limits.

    This is like trying to recreate the Linux kernel from scratch, except that we don't even know what 90% of the drivers are supposed to do!

    --
    It's such a fine line between stupid and clever.
  32. so they're the tuner generation of biologist by Brigadier · · Score: 1


    start with a regular old cell then tweak and tune the hell out of it. Then keep dyno'ng the creation until they get what they want.

    1. Re:so they're the tuner generation of biologist by Anonymous Coward · · Score: 0

      So they are just ricers? What is the genetic equivalent to spinners and black lights?

  33. Yes! by God+of+Lemmings · · Score: 1

    This is proof that the flying spaghetti monster created all life.... and midgets!

    --
    Non sequitur: Your facts are uncoordinated.
  34. blah blah blah risk! you cannot play god. by 2057 · · Score: 1

    I mean really it's getting, If we do create intelligent beings that destroy us, well than isnt that all part of god's design?! Stop the Jesus Freak. Save Science! The more we allow people who aren't smart to set limits on the abililties and exploration of the intelligent the more we are working against our species best interest. I'm sorry if i offended anyone but I'm tired of hearing people whine about issues based on religious grounds. Can't we just be like Krypton!

    --
    For The Best Jazz/Hip-hop fusion > COlD DUCK
    1. Re:blah blah blah risk! you cannot play god. by Bryansix · · Score: 1

      I think it is hard to argue that a rouge bacterial colony that eats everything in it's path is more intelligent then the human race.

    2. Re:blah blah blah risk! you cannot play god. by corngrower · · Score: 1
      So, what's so special about a rouge bacterial colony? Why not vert or cyan colored ones? (I think the word you were looking for was 'rogue').

      Aside from that, the parent poster was complaining about those that were against it because of religious reasons, not because of the potential ecological resons, one of which you mentioned. Think about and understand what the parent poster said before criticizing.

    3. Re:blah blah blah risk! you cannot play god. by anubi · · Score: 2, Insightful
      I consider myself spiritual, yet my concept of God is thus:

      God created the Universe, Earth, and everything in it.

      "Science" is the word we use to describe the Study of God's Creation. Hence, science is the study of God himself by witness of His Creation.

      I will NOT tell you who God is. Or what He wants. I do not know. And it is my firmest belief no one else does either.

      We are trying to understand how we came to be.

      I have to take as a given that if I was created with a sense of curiousity, my Creator intended me to use it to try to find Him, wherever and whatever He is.

      He may even be another set of completely natural processes following laws of probablity... how am I to know until we study, contemplate, and hopefully finally understand?

      I believe the the worst we can do is to do nothing.

      If God had wanted Sheep, he would have left it at that.

      Our Creator has already also provided us with all sorts of tools we can adapt and use as we see fit. We have already known about the atoms that make us up for some time... now we are learning more about actually how to assemble them in other ways. How is this any more wrong learning how to ignite wood so we can warm ourselves on a cold night?

      To sum up, from all I have seen and understand, Science is the truest study of God possible, as the basic tenents of the Scientific Methods rely on observations and reproducible phenomena, not hearsay. This observable phenomena was authored by God himself, using God's laws ( aka "Laws of Physics" ) that no man can put asunder.

      I will not say I am "religious" because I believe "religion" is the word we use to describe how Man creates God in his image.

      It is my strongest belief that Religion has very little to do with God and a helluva lot to do with maintaining hierarchical authority and obedience in the religious organization.

      In those cases, a God was created to give an illusion of authority so the "middlemen" who know how to play the game can use their God to claim authority over the masses.

      Read Stanley Milgram's research on "Obedience to Authority" if you need any reason to question just how prone to subordination we are. It all goes back to basic economics, as it requires a lot less effort on our part to follow than to lead, but if you can get enough followers, its worth your while to lead.

      If I am wrong, may God have mercy on my soul.

      --
      "Prove all things; hold fast that which is good." [KJV: I Thessalonians 5:21]

    4. Re:blah blah blah risk! you cannot play god. by anubi · · Score: 1
      The problem boils down to this:

      There is just so much stuff I do not know, and the more things I find out, the less confidence I have in things I once thought to be immutable and true to be so.

      Geez, onset of Alzheimer's???

      --
      "Prove all things; hold fast that which is good." [KJV: I Thessalonians 5:21]

  35. Slavery by Peter+Cooper · · Score: 2, Funny

    bioengineering organisms to do specific tasks such as produce hydrogen or ethenol

    Isn't this a form of slavery?

    1. Re:Slavery by aduzik · · Score: 2, Insightful
      You laugh at that, but I know people who *really think* that using microorganisms to do our bidding is a form of slavery. There are people who are honestly opposed to using recombinant organisms to produce oh, say, insulin.

      And you can't point out that those organisms exist in an environment where they reproduce in numbers that would never be possible in nature. According to them -- well, one person in particular -- "it doesn't matter how loosely we hold the whip; it's still a form of slavery." That's more or less a direct quote.

      And when you point out the symbiotic relationships that already exist in most living organisms -- animals in particular -- they refuse to believe that it's true. Something about the military-industrial complex of medicine trying to make us believe what they want us to believe or some crap like that.

      It's hard not to laugh when someone tells me that humans are evil evil creatures for creating antibiotics and vaccines. Because someone think of the poor bacteria and viruses! I only wish I were joking right now.

      --
      If it's not one thing it's your mother.
    2. Re:Slavery by Anonymous Coward · · Score: 0

      Yikes. What forums do you hang out on? I guess there are equally staunch anti-science nutters on the left, too.

    3. Re:Slavery by Anonymous Coward · · Score: 0
      Isn't this a form of slavery?

      And?
      Who gives a shit?
      If it's slavery and we bennefit, then all hail slavery I say!
  36. I can't believe they would do this by Sycraft-fu · · Score: 4, Funny

    They risk making the Flying Spaghetti Monster furiously angry and being strangled by His Noodly Appendage. We should recognies that there are things man was not meant to do, and leave it firmly in the realm of pasta.

    http://www.venganza.org/

    1. Re:I can't believe they would do this by rinkjustice · · Score: 1

      I hope you were wearing your full pirate regalia when you posted that!

    2. Re:I can't believe they would do this by Alsee · · Score: 1

      Blasphemy!
      May the Invisible Pink Unicorn smite you with her holy hooves!

      -

      --
      - - You can't take something off the Internet! That's like trying to take pee out of a swimming pool.
  37. Correction by Sheepdot · · Score: 1

    Abiogenesis is impossible. You cannot create life from non-life. If you could, then creationism wouldn't be a joke. And for that matter, neither would be macroevolution.

    1. Re:Correction by micromuncher · · Score: 1

      Sorry, Miller's experiment shows basic amino acids from non-life, the interactions of which create life (or so the story goes, which is still the big investigation.)

      --
      /\/\icro/\/\uncher
    2. Re:Correction by Verminator · · Score: 1
      Impossible?

      Electric light bulb.

      Heavier than air flying machine.

      Travelling beyond the edge of the map.

      The only absolute is: Absolutes are subject to change.

      --
      "The more corrupt the state, the more it legislates." - Tacitus
  38. oops! my fault! by smartsaga · · Score: 1

    I guess I should not have left that sandwitch behind the couch...

    Now they found it after this last heat wave and they found new life growing on it...

    I wonder what they will go with next? grass in the ass? That would be a start from the scratch...es!

    Have a good one.

    --
    ===== "Every head is a different world so don't invade mine you FREAK!" smartSAGA said
  39. OT: what is your signature from? by djbentle · · Score: 1

    I've seen your posts before and I've always wondered what your signature is from. It sounds cool, if it's book or something, it might be something I'd like to check out.

    1. Re:OT: what is your signature from? by Anonymous Coward · · Score: 0

      It's from Blade Runner

    2. Re:OT: what is your signature from? by Anonymous Coward · · Score: 0

      Thanks, maybe it's time to watch that again, I apparently don't remember very much.

    3. Re:OT: what is your signature from? by n6kuy · · Score: 1
      --
      If you disagree with me on social issues, then it's pretty clear that you are a narrow-minded bigot.
  40. stamp out "vitalism" for sure by peter303 · · Score: 1

    There are still a number of theories out there that claim there is a special essence that only living matter possesses and not in its constitute chemistry and physics. This essence is passed from being to being through the reproductive chain. It also could be passed by contaminate contact with living matter, or distilled like the "life force" in Star Wars or Frankenstein. The absolute refutation of vitalism would be to construct living matter directly from chemicals.

    Vitalism has been used (and still is) to support the contention of a Creator- living matter had to arise somewhere? It has been used to explain disease processes, but scienitifc medicine has modtly killed this aspect. A corollary of vitalism is a mind that is greater than the physical brain, which could make artificial minds impossible.

    1. Re:stamp out "vitalism" for sure by Anonymous Coward · · Score: 0

      This "special essence" has a name: information. No manmade DNA of sufficient length has sufficient information content in terms of the native processing methods of the cellular machinery. These are: most of the possible base sequences of fifteen bases occur at most once, and the sequences that produce a sufficient set of proteins to drive the protein manufacturing system are present.

  41. They use Intelligent Design, thus they are Gods by Anonymous Coward · · Score: 0

    'biohacking' style of experimentation is God's thing.

  42. Ethenol? by slickwillie · · Score: 2, Funny

    Maybe they can creat a bionic spell checker.

    Also, the obligatory:

    I'd like to see a Biowulf cluster of these.

    All your biohacks are belong to us!

    1. Re:Ethenol? by slickwillie · · Score: 1

      Maybe they can creat a bionic spell checker.

      And I guess I'll need it when they do.

    2. Re:Ethenol? by micromuncher · · Score: 1

      Ethanol (CH3-CH2-OH) is the alcohol found in alcoholic beverages.
      Ethenol (CH2-CH-OH) is vinyl alcohol.
      So... :-P

      --
      /\/\icro/\/\uncher
    3. Re:Ethenol? by VultureMN · · Score: 1

      Nah, you spelled it right:

      $man creat

      NAME
                    open, creat - open and possibly create a file or device

      SYNOPSIS
                    #include
                    #include
                    #include

                    int open(const char *pathname, int flags);
                    int open(const char *pathname, int flags, mode_t mode);
                    int creat(const char *pathname, mode_t mode);

      Etc, etc, etc.

    4. Re:Ethenol? by slickwillie · · Score: 1

      The story goes that when Dennis Ritchie was asked what he would do differently if he had to do Unix over, he said "I would spell 'creat' with a second 'e'."

    5. Re:Ethenol? by Anonymous Coward · · Score: 0

      well, but vinyl alcohol is just the enol form of acetaldehyde, isn't it? So it would rapidly convert to the stable form. At least 99.9% of molecules are normaly in a form of an aldehyde in this case.

    6. Re:Ethenol? by micromuncher · · Score: 1

      Uh the thread was about a spelling mistake, which it might not be...

      --
      /\/\icro/\/\uncher
  43. Scientists vs. artists by jesser · · Score: 1

    Some of the scientists involved are saying its more of an art instead of a science due to its 'biohacking' style of experimentation.

    Shouldn't that be "Some of the artists involved are saying..."?

    --
    The shareholder is always right.
    1. Re:Scientists vs. artists by putko · · Score: 1

      Exactly. I've also come to view GNAA, those nasty high-tech trollers as some sort of nasty performance art group.

      The thing is, the worst they can do is make someone look at goatse or Mr Hands -- they aren't going to turn you into grey goo.

      At some point hacker/tinkerers will be doing this stuff, and then a bit later, "artists". There will likely be a lot of problems when this happens.

      Now you can design PCBs, send off your files and get PCBs in your hand a few days later. I can imagine there will be similar services for customized bacteria.

      --
      http://www.thebricktestament.com/the_law/when_to_s tone_your_children/dt21_18a.html
  44. Not news by digitalderbs · · Score: 2, Informative

    Molecular biologists have been cloning genes in prokaryotes and eukaryotes for tens of years. It's not a new idea to clone a series of genes that work cooperatively to change biochemical behaviour of an organism.

    Something I find more note-worthy, as a biological chemist, is a new trend to expand the amino-acid table (past 20). Many of the codons (DNA or RNA triplets) are degenerate or they are stop codons. The idea is to add synthetic amino-acids to specific tRNAs. Chemically modified amino-acids are incorporated at the desire of the molecular biologist. This technology has already been developed, and the scientists in this field (not myself) are discussing using directed evolution with organisms with an expanded codon base. Very interesting.

  45. Actually by galdosdi · · Score: 1

    "It's only an ethical problem if the creation has free will." Actually, it's also an ethical problem if its existence could lead to trouble, like some bacterie going wild and eating grass or whatever instead of oil, like they were saying. The fact is, if something "goes wrong" repurcussions could affect everyone. Since when is doing things that could harm others ethical?

  46. patented life by Alexis+Boulva · · Score: 1

    "Already, synthetic biologists have created a polio virus and another smaller virus by stitching together individual genes purchased from biotechnology companies."

    so... i see we can patent life now?
    perhaps we should attempt the founding of a free(speech+beer)/open genetic library... come to think of it, that would seriously kick ass :) it would be like the next step for computer geeks' war against boredom.

    1. Re:patented life by rdwald · · Score: 1

      You guys would be really happy to know that when the subject of licensing issues came up at a synthetic biology conference I attended back in October, there was only one question: "GPL or BSD-style?" Seriously, folks, we are you. Biologists aren't scary people who try to play God and own everyone's genetic sequence; we're also code hackers, though we may hack a different type of code.

  47. LFS? by iminplaya · · Score: 1

    I tried that. Too many things wouldn't compile, and I'm too lazy to find out why right now. So I switched back to Slack.

    --
    What?
    1. Re:LFS? by jcuervo · · Score: 1

      Core dumps? (Ew.)

      --
      Assume I was drunk when I posted this.
  48. Mind can't be explained? by Trinition · · Score: 1

    The mind (by definition) cannot be explained by science...

    You claim the mind, by definition, can't be expolained by science. Mind is in quotations. What is this definition you're referring to? I"m not familiar with it.

    I've learned a bit about neural networks and have been impressed with what neural networks with very few neurons (i.e. tens) can do. The human brain has 10's of billions of neurons. That is a huge difference in magnitude! I am not so arogant as to suggest we can presently know what a neural network of that size can or cannot accomplish. Instead, I have faith that it is sufficiently complex to explain everything we attribute to "mind" and "spirit".

    Hopefully, someday, we'll be able to buld neural networks (artificial or bilogical) on the scale of the human mind and submerge it an an emersive environment as our own mind is, and we may finally begin to realize more about our own reality.

    P.S. Please do NOT start to use transistor count in processors as a corralary because they are not at all similar to a neural network... each human neuron has, on average, a connection to 1,000 other neurons -- those connections critical and the human brain has trillions of them!

    1. Re:Mind can't be explained? by fanblade · · Score: 1

      Well, first of all, if you don't believe in free will then there's no use worrying about this because it's impossible for you to change yourself. Your environment is at the wheel and you're just along for the ride. Luckily, I'm a part of your environment so you'll forgive me if I steer you in a different direction for a moment.

      See this cousin post for a good explanation of the mind. Do you believe that you are responsible for making your own choices (as opposed to your environment having made all choices for you)? If not, that's OK. I really can't blame you since you're just being 100% reactionary. But if you do believe in personal responsibility -- the mind is our only valid explanation.

    2. Re:Mind can't be explained? by Trinition · · Score: 1

      OK fair enough.

      Of course if free will doesn't exist, then you don't have it either, and everythign you've just posted is driven by the cumulative stimuli in your brain, including recent discussions about free will, my post, everthing you've learned before, and the tempoerature in the room at the time you wrote your post.

      It seems its an unprovable argument either way?

    3. Re:Mind can't be explained? by fanblade · · Score: 1

      Of course you're right about that one. It's impossible to write a proof for such concepts as the mind, the soul, the origin of the universe, etc. But I do believe that we can arrive at meaningful beliefs by discussing these issues and exploring the consequences of our beliefs.

      As I mentioned in another post, I was quite young when I first considered the possibility that all our decisions were really just illusions. If that were true, then I could safely relax my morals and do whatever the hell my body felt like. There would be no need to worry myself with decisions, because I could comfort myself in the fact that I had no control over those decisions anyway. But even as a child, considering the motto "it's not my fault" sounded so horribly wrong. It is wrong. The worst examples of human beings are those that act without feeling any shred of personal responsibility. It's ironic -- I'm not an optimist by any stretch, but I believe in free will. Whether that belief is truly mine or not, I'm certainly glad I believe it.

  49. Hmm... by SuperKendall · · Score: 1

    I think they had better keep an eye on their grad students.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley
  50. If there is patented life then ... by WillAffleckUW · · Score: 1

    so... i see we can patent life now?
    perhaps we should attempt the founding of a free(speech+beer)/open genetic library...


    I think MSFT already patented it. Especially the bugs which are now referred to as "features".

    --
    -- Tigger warning: This post may contain tiggers! --
  51. Intelligent Creator by Anonymous Coward · · Score: 0

    No, he gave us free will and a conscience so we can choose to follow Him and His Word or disobey. He gives us choices and consequences/rewards.

  52. Answer by IthnkImParanoid · · Score: 1

    Yeast is itchy. I see no mention of itchiness in the article; therefore these organisms are far superior than their itchy counterparts.

    --
    It's nothing but crumpled porno and Ayn Rand.
  53. The scientists can't even create a fly. by ynona · · Score: 1

    O people! a parable is set forth, so listen to it: surely those whom you call upon besides God cannot create a fly, even if they all gathered for it, and should the fly snatch away anything from them, they could not take it back. Weak are the invoker and the invoked. (Quran 22:73)

    1. Re:The scientists can't even create a fly. by xmorg · · Score: 1

      Puh, the Judeao-Christian god never said that we were not allowed to create life from scratch. Nor did he outlaw biohacking.(in the laboratory sense)

  54. nothing to see here by cahiha · · Score: 1

    Move right along, there's nothing new to see here. A bunch of enterprising scientists have found a new name for the gradual maturation of biotechnology and genetic engineering.

    There is neat stuff happening in this area, but there was neat stuff happening before people gave it a new name.

  55. Dogma bit set low for some, high for others by birge · · Score: 1

    You just dismissed the deeply held beliefs of over half the world's population. Who's the troll, again? Being certain there is no God is just as "religious" a statement as to be certain there is one. Moreover, if you're going to operate on blind faith and not reason, why in whomever's name would you go with atheism? I can see saying "I have no idea regarding the existence of a creator" but to come down with a definite conclusion, and for that to be a hard bet against the home team? That's just crazy. Seventy-two virgins crazy. Ever hear of Pascal's Wager?

    1. Re:Dogma bit set low for some, high for others by Jackmn · · Score: 2, Informative
      Ever hear of Pascal's Wager?
      Pascal's Wager is irredeemably flawed. It only works if the Christian conception god is assumed, and all others are ignored.
    2. Re:Dogma bit set low for some, high for others by Jackmn · · Score: 1

      Apologies for the comma splice.

    3. Re:Dogma bit set low for some, high for others by kevinwal · · Score: 0

      Maybe so, but the odds are better than with atheism.

    4. Re:Dogma bit set low for some, high for others by Anonymous Coward · · Score: 0
      Ever hear of Pascal's Wager?
      Yes, but some people have principles.
    5. Re:Dogma bit set low for some, high for others by birge · · Score: 1

      I agree that Pascal's Wager is bogus. I was joking about that part. However, I wasn't joking about the notion that being certain of no God is just as religious an idea as being sure there is a God. They are perfectly symmetric beliefs, and insofar as faith is concerned, are essentially the same. If there can be no proof of God, there can be no proof of Godlessness. I know that's not logically neccesary, but I believe given the way the world is, it is nonetheless true.

    6. Re:Dogma bit set low for some, high for others by NoOneInParticular · · Score: 0, Offtopic
      The symmetry is broken by examining the nature of inquiry that allows the proof or disproof of the theories. The belief in the existence of something can only be verified (simply by showing that the thing exists). However, it is impossible to falsify the statement. The belief in the non-existence of something is -- for the same reason -- not verifiable, only falsifiable (again by showing that the thing exists).

      Your statement 'If there can be no proof of God, there can be no proof of Godlessness' is thus false. The logically correct statement is '... there can be no disproof of God, and there can be no proof of Godlessness', or alternatively, getting rid of a couple of negations: the existence of God can be proven, not disproven, the absence of God can only be disproven, not proven.

      I hope the asymmetry is clear.

  56. Zodiac by Anonymous Coward · · Score: 0

    The definitive word on this is "Zodiac" by your favourite author Neal Stephenson...and it shows up the rest of his stuff as pulp written trash too ;-)

    ISBN: 0099415526

  57. Adds a new meaning to "overlords" posts by davidwr · · Score: 1

    Dare I say it?

    "I for one welcome our new scientific overlords-of-creation."

    *groan*

    --
    Knowledge is how to play a game, intelligence is how to win, wisdom is knowing what game to play.
  58. Waiting for the O'Reilly book by Prof.+Pi · · Score: 1
    Bioengineering Hacks, of course.

    Wonder what they'll put on the cover.

    1. Re:Waiting for the O'Reilly book by HellYeahAutomaton · · Score: 1

      I, for one, am waiting for the A Developer's Notebook edition.

      It's going to be much cooler than Bioengineering Hacks, Bioengineering Cookbook, and Bioengineering In a Nutshell.

    2. Re:Waiting for the O'Reilly book by loqi · · Score: 1

      Clearly, the logical answer is a computer.

      --
      If other reasons we do lack, we swear no one will die when we attack
  59. Life and Software synthesis are one and same by SilentReallySilentUs · · Score: 1

    When can we learn that the "process" behind building bridges, buildings, and other lifeless hardware doesn't apply to life or software? These are fuzzy and constantly evolving processes - boxing them into processes, steps, or rules is not the right approach.

    1. Re:Life and Software synthesis are one and same by wolverine1999 · · Score: 1

      Nonsense - have you never heard of stuff like genetic algorithms and artificial life?

    2. Re:Life and Software synthesis are one and same by SilentReallySilentUs · · Score: 1

      Exactly my point. Genetic Algorithms is the way to think about these things.

  60. Until what they create has a brain... by MikShapi · · Score: 2

    Until what they create has a brain and is capable of rational thought I don't see where the moral implications of this differ from material science.

    --
    -
  61. Feature by Anonymous Coward · · Score: 0

    Yes it's a feature called free will.

    1. Re:Feature by msh104 · · Score: 1

      that is, if a thing like "free will" exist.

  62. Simpsons quote by Anonymous Coward · · Score: 0

    "God schmod, I want my monkey-man!"

  63. Scientists Creating Life From Scratch? by Anonymous Coward · · Score: 0

    The title and the article have NOTHING to do with each other!

    When the hell did Slashdot become the New York Daily News???

  64. test for determining mind? by sevinkey · · Score: 1

    Is there a definitive test for determining whether a creature has a mind in addition to having a brain?

    Is there a way to rule out that a particular animal does not have a mind?

    Is there a way to show that all or even most humans possess a mind?

  65. scientific research by sevinkey · · Score: 1

    The one reason I would like to see research like this done is to eventually see if we can create life through chemical processes. The results would probably raise far more questions than it answers if such a process was discovered or was ruled out as impossible for some unknown reason.

    That's assuming this article is refering to trying to take the chemicals that make up DNA to create organisms, rather than playing around with DNA. The latter would not be particular useful for insight into philosophical questions about life.

    If they are just playing around with DNA, what's the difference between "synthetic biology" and "genetic engineering"? That would really make this old news if they're splicing DNA.

  66. No, Becoming a FSM by soft_guy · · Score: 1

    I think it is pretty clear that we are becoming a Flying Spaghetti Monster.

    --
    Avoid Missing Ball for High Score
    1. Re:No, Becoming a FSM by GuniGuGu · · Score: 1

      I, for one, welcome our new Carbo Hydrate Overlord!

      --
      "Honeeey I'm 127.0.0.1"
  67. Life from Scratch? by vanka · · Score: 1

    Not to take anything away from the scientists involved (they are at the top of their field), but I do not see in TFA where the claim came that they are creating life from scatch. Reading the article, I see that they have purchased genes from other comapanies or getting the genes from other organisms, arranging these genes in new ways, and then injecting them into other organisms. While this in itself is a big breakthrough and accomplishment, it does not live up to the hype of creating life from scratch. This is more like cutting out whole paragraphs or pages (not letters) out of several books, arranging them in a new and interesting order, and pasting them into yet another book. Creating life from scratch would be akin to writing and printing a book from scratch. Note the scientists are using pre-existing genetic information to create new strains of bactria/viri; they are not writing a new genetic code from scratch.

    Also, just to play the devils advocate; this (to me) seems to be proof for intelligent design rather than against it. The scientists (who, I assume, are highly intelligent) are creating new organisms. These new organisms are not evolving randomly by themselves, but instead evolved (were created?) under the watchful eyes of highly intelligent beings. We would never (in most likelyhood) have seen these organisms if the scientists had not started tinkering in their labs. An interesting point to ponder.

  68. IDIOTS, when CANABIS is the answer!! and no patent by cheekyboy · · Score: 2, Funny

    Yeah typical,

    "oh lets invent something because the free nature stuff cannot be patented and sold for profits"

    Any one can clone natures best, cloning plants is trivial.

    So - http://www.hempcar.org/

    So if the damn politicans and christian nut cases would just die of cancers overnight, we could have some real prople with brains running the show to everyones benefit not just the corporate elites nutjobs.

    --
    Liberty freedom are no1, not dicks in suits.
  69. From Scratch != Combining already created cells. by TheCeltic · · Score: 1

    Hey! Look what I made.. a computer! I did it from scratch! I used an Intel Motherboard and CPU, a Maxtor Hard Drive, a NVidia Video Card, a case from AlienWare... etc.. Not exactly from scratch.

    --
    =-=-=-=-=-=-=-= - The Celtic - =-=-=-=-=-=-=-=
  70. ethanol? by bariumLanthanide · · Score: 1

    to do specific tasks such as produce hydrogen or ethenol.
    Hydrogen maybe, but ethanol? Why not just use yeast?

  71. Definetly Intelligent Design by TheCeltic · · Score: 0, Troll

    Definetly Intelligent Design.. The other "method" (Theory) has yet to be proven AND seems too slow (if it was to work)...

    "So a new breed of biologists is attempting to bring order to the hit-and-miss chaos of genetic engineering by bringing to biotechnology the same engineering strategies used to build computers, bridges and buildings."

    --
    =-=-=-=-=-=-=-= - The Celtic - =-=-=-=-=-=-=-=
    1. Re:Definetly Intelligent Design by Anonymous Coward · · Score: 0

      The other "method" would be selective breeding.

  72. Re:IDIOTS, when CANABIS is the answer!! and no pat by Anonymous Coward · · Score: 0

    So if the damn politicans and christian nut cases would just die of cancers overnight, we could have some real prople with brains running the show to everyones benefit not just the corporate elites nutjobs.

    Fact: More than 90% of the people in the United States Congress, and the White House, and the Supreme Court, have backgrounds in law. They're either lawyers, or they went to school for a law degree. Of course the former are always the latter, but not vice versa. Anyway, science types, and engineers never run for political office. They choose to help the world realistically, not through red tape and taxes.

    If the younger lawyers didn't replace the fuckers who are in office, it would be the business assholes. That's just what we need, big business not only lobbying Congress, but actully RUNNING it.

  73. Best paragraph ever... by lazlo · · Score: 1

    With a $42.6 million grant that originated at the Bill and Melinda Gates Foundation, Berkeley researchers are creating a new malaria drug by removing genetic material of the E. coli bacterium and replacing it with genes from wormwood and yeast."

    OK, so here we have a bunch of money, originating from Bill Gates, going to Berkely (of BSD and LSD fame) to do high-tech cross-breeding of fecal bacteria, the plant responsible for the drug-like qualities of absinthe, and the organism responsible for the beer-like qualities of beer.

    Some day soon, a hallucinigenic, but otherwise shitty beer will take over the world. I'm convinced of it.

    --
    Pound! Bang! Bin! Bash! is this a shell script or a Batman comic?
  74. Wow. I'm impressed. by rdwald · · Score: 1

    Not a single "OMG! The evil biologists are creating life! Soon they'll create bio-grey goo and kill us all!!!" comment. I am pleasantly (and greatly) surprised. Incidently, I work in this field, and while we're certainly not creating life (I think that was thrown in by MSNBC's crappy reporters), we're basically trying to apply EE-type methods to biology. You guys should love this stuff.

  75. Re:Becoming a god, or making brownies. by arbitraryaardvark · · Score: 1

    If, hypothetically, I wanted to make brownies,
    and I started with cocoa and sugar and flour and eggs and butter and vanilla extract and a pinch of salt (optional raisins, walnuts or ganja), it would be fair to say that was from scratch.
      I wouldn't need to start from sugar cane and wheat and chickens and whole milk etc.

  76. Who gives a shit about ethics? by Anonymous Coward · · Score: 0

    Let's advance science. Who cares about ethics, they are just a roadblock to progress.

    Forward!!!

  77. Comment removed by account_deleted · · Score: 0, Offtopic

    Comment removed based on user account deletion

  78. Comment removed by account_deleted · · Score: 0, Offtopic

    Comment removed based on user account deletion

  79. Sir Arthur told us that... by Anonymous Coward · · Score: 0

    Sir Arthur Clarke once said that:

    "Any sufficiently advanced technology is indistinguishable from magic"

    Replace "technology" with "art" or "magic" with "religious visions", and you'll get the same perception, but a different way to articulate it than in say... Kansas

    Funny enough, wasn't Kansas during the Civil War a place that was regarded as pagans by the southerns because of their early support of science in their schools ?

    Certainly, in some places evolution doesn't take place.

  80. Comment removed by account_deleted · · Score: 2, Funny

    Comment removed based on user account deletion

  81. The circular hipocrasy makes my head spin. by Anonymous Coward · · Score: 0

    So... We bitch about keeping Intelligent Design out of schools, and yet when scientists try a little Intelligent Design themselves we cry "They're playing god!"

    Well, which is it?

    Either Life was created by God and so we are also playing God or Life was created by natural processes in which case we are playing... natural processes.

  82. Re:Becoming a god, or making brownies. by Hafren · · Score: 0

    Recipe to make brownies from scratch: 1. Create Universe...

  83. viable . . . by Anonymous Coward · · Score: 0

    ID proponents claim that a complex being is needed to explain other complex beings.

    It's bullshit! You cock sucking motherfucker.

  84. DNA v.2 by ichigo+2.0 · · Score: 1

    I guess you won't be satisfied until someone designs a replacement for DNA and construct new kinds of life from it. :P

  85. ...no matter how many beers I had... by Anonymous Coward · · Score: 0


    +1 funny

  86. What controls the decision? by Kris+Thalamus · · Score: 1

    Humans place a lot of importance on this. Why? Because most of us believe that we can make choices that aren't dictated by our environment, that somehow we can truly change ourselves. This is impossible with a wholly naturalistic view of the universe.

    This is where I'm not understanding you. If our behavior is subject to the control of our biological constitution and its environment, then we should be able to change ourselves by altering our environment and/or our biology.

    1. Re:What controls the decision? by fanblade · · Score: 1

      You're right, that's probably where we're losing each other.

      You've summarized it pretty well. Without free will our behavior is wholly dependent on our body's architecture and external stimuli. Of course we could change either of those things to change our behavior. However, we certainly wouldn't be "changing ourselves" because it wasn't we who made the decision to change those factors. The environment simply changed itself in an indirect way.

      In other words, it would be like saying your computer decided to change you by running the applications that you tell it to. Interacting with your computer programs definitely affects you. And you are an important part of the computer's environment. But does that mean the computer changed itself? I suppose it depends on your perspective, but from a human's elevated point of view, we see that a computer doesn't change itself. We do all of the changing.

      Does that perhaps alter your perspective at all, or would you still say that a being with no free will can change itself?

    2. Re:What controls the decision? by Kris+Thalamus · · Score: 1

      You've summarized it pretty well. Without free will our behavior is wholly dependent on our body's architecture and external stimuli. Of course we could change either of those things to change our behavior. However, we certainly wouldn't be "changing ourselves" because it wasn't we who made the decision to change those factors. The environment simply changed itself in an indirect way.

      Surely that would be stretching the definition of "environment". The activity of the person is still an important link in the causal chain. A decision doesn't suddenly lose its status as a decision once we've discovered why a particular response was chosen over another.

      In other words, it would be like saying your computer decided to change you by running the applications that you tell it to. Interacting with your computer programs definitely affects you. And you are an important part of the computer's environment. But does that mean the computer changed itself? I suppose it depends on your perspective, but from a human's elevated point of view, we see that a computer doesn't change itself. We do all of the changing.

      The computer can influence my behavior, and I can influence the the computer's activity. We don't normally blame or praise computers because they are not subject to the controls of punishment and reward in the way that humans are. Verbal fault-finding is unlikely to change a computer's future behavior unless a technician intervenes. This is why we don't use words like "responsibility" when we refer to computer errors.

      Does that perhaps alter your perspective at all, or would you still say that a being with no free will can change itself?

      Well, the change could be initiated by an identified external force, or the change could be capricious. Either way, the agent is changing itself in the sense that it's executing an action that alters its future actions.

      Do you contend that the agent only changes itself when the reason for the change is unknown?

      I still see the will as being most free when it is random. When we examine the genetic and environmental influences on human behavior, we have a better understanding of the principles under which behaviors are generated and modulated.

      I've enjoyed this dialogue and I hope that you write back.

  87. especially worrying by aneroid · · Score: 1
    Some of the scientists involved are saying it's more of an art instead of a science due to its 'biohacking' style of experimentation.
    i just saw the doom movie trailer today (i know, a bit late, reading up some prev /. stories)...and this is exactly how it will begin!

    i welcome our new...oh shpx it.

    when can we grow our own "implants"?
  88. God! You are such a baby! WAAAH. cry to mommy! by Anonymous Coward · · Score: 0

    Of all the lame sunday afternoon jokes that are so beloved by christians, I think this is one of the worst. It basically makes their all-powerful god sound like a stingy little toddler.

    You can imagine all sorts of interesting alternate endings. Like man throwing the dirt in God's face. After which he started crying, and then ran home to His Mommy. Then he destroyed the universe.

  89. Re:Not Really by Anonymous Coward · · Score: 0

    Intelligence of the kind you are talking about is relative. If this kind of genetic tinkering generates something complex or useful, we are apt to call it "intelligent". However, if it does something with adverse unintended consequences, it will hardly be judged as "intelligent". Likewise, it might be intelligent because it benefits the person (corporation) that creates it, but detrimental to everyone else. Whether or not its "intelligent" depends on your perspective.

    My guess is that such technology will be both be used and misused. Whether we survive the latter is anyone's guess.

    The fact that a design is perceived as "intelligent" explains nothing about its origins, but rather only something about the state of mind of the observer. Hence, one can hardly use such an artifice to explain the origin of species in the natural world. Besides, it isn't necessary as a perfectly good and extraordinarily well-corroberated SCIENTIFIC theory is available, namely evolution by means of natural selection.

    Nice try at spining, even when it is pointless to do so.

  90. Re: At this point God needs good lawyers. by Anonymous Coward · · Score: 0

    We've reached a level of scientific understanding that does seem to suggest that in the court of rational opinion God does indeed need lawyers. This seems mostly because he seems to be getting such a poor quality defense from the religious zealots and blind believers.

    For those who seem to believe they can explain anything and everything by a belief in god, I would suggest that they do us all a favor and explain themselves away.

  91. accidental life by falconwolf · · Score: 1

    The fallacy in your statement is in the fact that these organisms weren't merely created by accident - they were intelligently created by scientists in a lab. So the fact that this occurred only reinforces the supposition that it could not, in fact, happen on accident

    I don't know how you come up with it saying it's not being possible for life to happen accidentally. I didn't see anything like this in the article. I read before but because of your remark I read it again, and here I must thank you because the in first reading I didn't see a page two so now I'll read that as well... Nope, I didn't even find one instance of "accident" in the compleat article.

    Falcon
  92. science and religion by falconwolf · · Score: 1

    I've never understood why science and religion must be at odds. Why can't one's deity be the one who caused these scientific laws and phenomena, and either nudged evolution a little bit here and there or maybe just planned it all in the beginning (like writing a program, or planning a chess game ahead) and set it loose?

    The previous pope, John Paul II, pretty much said as much. Something like "God" used evolution to create man or some such.

    Falcon
  93. Random (Free) or Caused (Determined)? by Kris+Thalamus · · Score: 1

    I didn't say human will is unaffected by the body's environment.

    If we are affected by our environment, then we should conclude that we are not truly free from its control.

    Yikes. How did you read fatalism from my post?

    Your notion that a lack of free will abdicates responsibility sounds like a form of fatalism to me.

    My previous post points out that a consequence of dismissing free will is dismissal of anyone's personal responsibility for their behavior.

    We could ask whether it's the temperature, the humidity, or the barometric pressure that causes rain, but no single element acts alone -- they all are responsible. If another car sideswipes my car after running a red light, we blame the person who violated the rule even though both cars were necessary in bringing the collision to fruition. We assign responsibility to the rule breaker as a convenient means of preventing future accidents.

    No matter how unpredictable your actions may be, randomness cannot provide the metaphysical truth of independent agency.

    A phenomena may be caused by a preceding event, randomly generated, or brought about by a stochastic synthesis of the above (e.g. white noise modulating a sine wave in an analog synthesizer). Can you give me an example of an event that is not random, not stochastic, and not caused by antecedent events?

    I'm not talking about "decisions" the way you're talking about them. Your body can react to stimuli, but that's not independent decision making.

    If a decision were independent of external control, would it not be random?

    In other words, you cannot alter the course of your own thoughts and actions unless you have free will.

    I could change my environment to alter the course of my behavior. I don't see why I would need a metaphysical agent to do that. And if we assume that my behavior is under the control of a soul, free will, a homunculus, or some such, then what controls the soul? I have a hard time imagining a first cause that isn't random.

  94. God's motivation by Anonymous Coward · · Score: 0

    My theory is, if God didn't want me to be enormously, grotesquely fat, He wouldn't have created dozens of varieties of Ben & Jerry's ice cream.

    Also, if you didn't want me to poop on your doorstep, you wouldn't have left all that soft grass around for me to wipe.

    I've got no problem with cautious bioengineering, but just because we CAN do something doesn't mean we should, or that God wants us to.

  95. Hi Fanblade by Kris+Thalamus · · Score: 1

    Thank you for taking the time to respond to my questions.

    Then again, believing in randomness itself takes a bit of faith. I think you would agree with that.

    I don't think it requires an undue amount of faith, unless you are trying to promote the solipsistic belief that every concept requires faith. We need only a bit of statistical analysis to establish that an outcome is random. I like to think of randomness as a platonic ideal. In that sense, some sequences of events more closely resemble theoretical randomness than others. It would be difficult to prove that an event was truly uncaused because in order to do so, we would need to systematically eliminate all mediating influences that could potentially instigate said event.

    One should remember that random events are not necessarily uncaused, but uncaused events would be random. We call an outcome "random" not because it is uncaused, but rather because it follows stochastic variation. For instance, there is evidence to suggest that the motions of a coin are subject to the laws of physics -- however, the outcomes of a coin flip manifest themselves probabilistically. This is because the forces acting on the coin are highly variable and favor no one side in particular.

    You are right to feel that we don't have perfect certainty, but that lack of certainty doesn't grant one the epistemological license to arbitrarily accept explanatory fictions. We shouldn't conclude that all ideas are equally erroneous just because our perceptions are limited and fallible. Science does not grant us perfect certainty, but it is still, nevertheless, useful.

    A place like this could provide the "super-existence" necessary to create ours. Is this my explanation for the universe? Hardly. It's just a feeble attempt at resolving the dilemma you've proposed.

    You admit that it is a feeble explanation; perhaps you should declare that it's an explanatory fiction and abandon it all together. I could use a similar "super-existence" to explain how my plumbing system works, but it wouldn't be a very useful or convincing explanation.

    It's important to keep in mind: free will isn't the only thing that defies logic.

    If your conception of free will admittedly defies logic, then it may behoove you to look into some of the research in the disciplines of behavioral science, genetics, and neurophysiology that explain why we do what we do.

    All we can say for certain is that nothing is certain; nothing is provable. Even the most basic beliefs are built on the tenet of faith.

    I'm a pragmatist. I'm not particularly concerned with what is ultimately true or false. I do, however, care about what works.

    I believe in them because I feel that without these things, our lives couldn't possibly have meaning.

    Are you saying that you believe in those things because they appeal to your sense of vanity, and not because you have evidence for their existence?

    Meaning is a pretty safe measuring stick if you think about it.

    I find meaning to be a very poor metric. First of all, we don't have units to measure the level of meaning that an object has. Secondly, a meaning will very greatly from one person to the next.

    But with it, there is the promise of truth. In my opinion, we were designed to use meaning as a heuristic for determining our closeness to absolute truth.

    Are you trying to tell me that a belief that feels meaningful is more likely to be true?

    If Slashdot locks the comments on this story, I would like to continue this discussion in an email exchange.

    My email address is selectivepressure a t gmail'com.

  96. Morality from a social standpoint by Trinition · · Score: 1

    But if you "relaxed your morals" and did whatever you felt like, you would be considered amoral. Amoral is mostly easy to define as "what's bad for society." That is, behaviors, which, if left uncheck, would decimate the population of a society.

    Take murder, for example. Show me a society who lets people get murder people over trivial angers, and I'll show you a society who doesn't exist. A society that kills its people off readily will implode.

    Hence, we have laws that support our moral values. And if you decide you don't have to be responsible for your actions, then you'll be removed from society (jail, death penalty, whatever).

    But that doens't mean you had to have free will to execute your amoral actions. Consider a network of computers. Suppose one computer started sending out voltage spikes on the network bringing it down. Well, it would be better for the network to have that computer removed. The computer didn't use free will to decide to send power spikes. It has a fault that causes it to do so. Where that fault came from is irrelevant.

    Likewise, we don't have to know why someone committed murder, it's still amoral. And, by "why", I don't mean self-defense vs. lack of respect for life, but the actual cumulative inputs throughout their life that led ot the deicsion to commit murder. That is far too complex. Hence, it will always be useful to talk in abstractions, whether or not they're based in spirit or science.