Biologist (Almost) Creates Artificial Life
Aditya Malik writes "Wired has an interesting story up about how a lab led by Jack Szostak, a molecular biologist at Harvard Medical School, is building 'protocells' from artificial molecules which are very close to satisfying the conditions for being 'alive.' 'Szostak's protocells are built from fatty molecules that can trap bits of nucleic acids that contain the source code for replication. Combined with a process that harnesses external energy from the sun or chemical reactions, they could form a self-replicating, evolving system that satisfies the conditions of life, but isn't anything like life on earth now, but might represent life as it began or could exist elsewhere in the universe.' This obviously raises some questions about creationism, not to mention some scary bio-research-gone-wild scenarios."
I won't count it as life until it can build more fatty molecules too.
is it grey, and is it gooey? in which case, it looks like the end of the world is nigh!
I know they aren't really Von Neuman machines, but that phrase always puts me in mind of a replicator apocalypse...
Admit it. You post strawman arguments as AC so you get modded Insightful for refuting them, rather than Troll
eh?
Curb CO2 emissions: Kill yourself today!
They might be changed into something that could terraform Earth 2.0 ?
Lifeforms here on Earth are unlikely to be suitable for such. This could be quite interesting actually IMO.
Support NYCountryLawyer RIAA vs People
life grown in a test tube environment is SOOO well adapted to a planet where other forms of life have fought a life and death battle for SIX BILLION YEARS.
I think many people should be doing this because it is similar to the Star Trek theory that life could come out in Silicon or something we do not know it as. Of course, I think science should also try and database as many species as it can especially since many species are dying off before they're being cataloged. We should strive to know all the viable lifeforms possible even if they're extinct or not a species yet. I think this is one of the reasons why SciFi and Fantasy books and games are so fun, to see what it is like interacting with different life forms.
As for the impact this has on people's belief on God. Personally, I know God exists, and it wouldn't shake my faith even if people start printing out lifeforms from their computer. Maybe I'll find people trying to reason away God more annoying, but it isn't my place to judge.
God spoke to me.
That seems slightly ironic in this particular case, simply because these protocells were "created" by this Jack fellow. I don't believe in Jack.
If this experiment is successful, it will finally prove, once and for all, that life was not created by intelligent design. How will it prove that? Well, if an intelligent being (the aforementioned biologist) succeeds in creating a life form, then it follows, logically, that the life form he creates is not the result of the work of an intelligent being. It's simple logic, and any idiot can see that.
Incidentally, all the generations that came before ours thought that life came from some intelligent being, but they were all stupid because they didn't live in the enlightened world that we live in today. There were no cars, computers, airplanes, and other technologies. They didn't have the Internet or Wikipedia. Thus, they were stupid. Today, we're much smarter than that and we know better than to believe in such nonsense.
McCain/Palin '08. Now THAT's hope and change!
He tried to create a phallic looking creature.
Similes are like metaphors
Since the scientist did the (almost) creating here, what questions would this raise? Now if the (almost) alive protocells had popped into existence by random chance and from a void of nothingness, that would raise some uncomfortable questions.
I judt got a nre Kinesis keybiartf so please excusr ant egregiou typos.
"This obviously raises some questions about creationism..."
Such as?
"Maybe there is no God? We were some experiment?"
The fact that life may be "creatable" does NOT infer that WE were. At least not at the hands of "gods" or other lifeforms.
That's the sound of 100,000 /.ers trying to come up with the perfect obscure movie reference. We'd better get out of here before it gets ugly.
Too late...
Failure to follow this advice may result in non-deterministic behavior.
Shortly after their creation the cells formed a new religion declaring their white coated man God. Also that their world/petri dish was in fact flat and that on Sunday their God did in fact rest/got drunk and watched football.
The dog was actually corn on the cob, but the implications for future man-dog relations are staggering.
I was just reading about this in The Living Cosmos by Chris Impey. Very good book btw, worth checking out from the library or even buying.
I'm glad Szostak is doing this though, it starts to fill in the gab on how cellular life started.
This reminds me of a joke:
One day a group of scientists got together and decided that man had come a long way and no longer needed God. So they picked one scientist to go and tell Him that they were done with Him.
The scientist walked up to God and said, "God, we've decided that we no longer need you. We're to the point that we can clone people and do many miraculous things, so why don't you just go on and get lost."
God listened very patiently and kindly to the man and after the scientist was done talking, God said, "Very well, how about this, let's say we have a man making contest." To which the scientist replied, "OK, great!"
But God added, "Now, we're going to do this just like I did back in the old days with Adam."
The scientist said, "Sure, no problem" and bent down and grabbed himself a handful of dirt.
God just looked at him and said, "No, no, no. You go get your own dirt!"
Just like the guys who keep ALMOST finding Higgs Boson. They should award an Almost Nobel. (I've qualified for the Almost Darwin Prize a few times as a teen. I don't know why I let them talk me into blindfolded skateboarding.)
Table-ized A.I.
There were questions about creationism? I mean, despite all the facts that say it can't be true. Mmmmmkay...
Ahhh...the great dumpster continuum. Many a free computer will be found there. -- sowth (748135)
Combined with a process that harnesses external energy from the sun or chemical reactions, they could form a self-replicating...
I'm no bioscientist, but could this project be modified to something which harvests energy from the sun and then can discharge it in a was in which electrical or bio-mechanical energy could be generated?
"This obviously raises some questions about creationism, not to mention some scary bio-research-gone-wild scenarios."
For the sake of brevity, we will not, however, be listing these questions here.
Combined with a process that harnesses external energy from the sun or chemical reactions, they could form a self-replicating, evolving system
It's called a Lava Lamp.
Voight-Kampff for short.
Saying "biologist (almost) creates artificial life" is like sating "slashdotter (almost) gets a date"... it could be completely meaningless.
Why does this raise any questions about creationism? To the best of my knowledge, there are essentially no creationists who argue that life was created by humans or any other intelligent organisms(unless they are squirming around on the stand, trying to avoid the establishment clause). And nothing in any current evolutionary hypothesis precludes artificially constructed organisms any more than they preclude artificially constructed computers and hammers. The fact that we can, almost, produce simple organism analogs doesn't mean anything one way or the other, though I suspect that it will be a very convenient mechanism for exploring the capabilities of (relatively) low complexity structures, and will provide the opportunity to do evolutionary experiments from well defined baselines.
As for the bioresearch gone wild scenarios: all advances in knowledge create the potential for trouble; but I suspect that it will be quite some time before any synthetic organism becomes much of a threat. The world outside is an incredible hostile place, crawling with microbes that have been slitting each others' throats in innumerable horrid ways for millennia. The interaction will be something like this:
[Synthetic wimp organism]:"Hi, I'm synthetic."
[Hardbitten wild bacterium]:"I fucking killed my own family over a nanogram of glucose."
[SWO]:*gulp*
[HWB]:"Hey, look, one of the thousands of antibiotic compounds secreted by fungi as part of the brutal chemical war of all against all."
[SWO]:*Dies horribly*
Creationism is based on faith, not arguments. Mountains of proof are enough to convince those who believe in what they wish were true, rather in what the evidence suggests.
Recall that bacteria have had around 4 billion years to turn Earth into a nanopocalyptic wasteland. Sure, they're everywhere, but they aren't dismantling everything else for parts. If this were a real risk, it would already have happened.
As a biochemist I'm surprised with the 'almost alive' statement in the article: they're still a long way to go. However, the work they are doing is interesting and is proof-of-concept for many elements of the RNA-world theory. I, like others, am surprised by the 'questions about creationism'. This show improper bias where this article doesn't approach creationism, but rather supports the validity of the evolutionary origin theory. The author has assumed that origin is a zero-sum game, and this is flawed and biased logic.
...... and idiots rule the world....
Whenever I start contemplating DNA (!), self-reproduction and the utter insanity of how complex the machinery of a single cell is, much less multicellular life, much less an animal, much less a self-aware brain, I just shake my head in wonder. There can only be one conclusion, really.
No, not God, that's utterly absurd. No, the conclusion is that life is really, really, really, REALLY unlikely. That's the answer to the Fermi Paradox. We are utterly unique, and I suspect that intelligent life is so improbable, that it requires 1e85th power cycles of the universe(s) for it to happen *once*. Of course, we have no idea how much "time" has passed since the last time it happened. We just wake up as a species and assume it must be happening everywhere.
Really, just contemplating the whole idea of DNA when it's really just a wet, sloppy pile of chemicals blows my mind.
Sometimes it's best to just let stupid people be stupid.
And I, for one, welcome our new artificial protocell overlords.
zosxavius photography
Look at this carefully. He is mixing ingredients...not creating anything. He is using "source code" from something else. There is no way he is going to create DNA or recreate the processes that each living cell goes through without stealing from something else. Let's get real and past the hype. He's trying to get headlines somewhere from people that are willing to get excited. Every heard of the car that runs on water!!!!
jsut athnoer menagiensls ltitle psrhae for you to dcoede. Why do we wtsae our tmie dnoig tihs?
We have to stop these mad scientists before they destroy the earth with their Large Hadron Colliders or create some sort of sentient goo that could destroy us all!
Arrrrgh! Run away!
Yeah, I'm being silly. Mod me down.
give me cells that reproduce and evolve and demonstrate that and then you'll raise questions about creationism. Otherwise you're just showing how desperate you are to disbelieve.
will their self replicating code be open source?
Call me when he can create an 20-something Kelly LeBrock and I'll be more interested.
(Disclaimer: Actually I find this kind of science fascinating, but that doesn't aid in making a joke)
These posts express my own personal views, not those of my employer
... a possibility to get large amounts of fatty molecules to get energy from the sun and other external sources? And this might be bioengineering gone wrong?! Sounds to me like we have a chance to use the obesity in America to create artificial life ...
Jack Szostak, a molecular biologist at Harvard Medical School
So when is it discovered that Harvard is another front for The Umbrella Corporation?
Isn't HOW the scientist creates life more important than IF the scientist creates life when considering it's relevance to proving or disproving Creationism. If the scientist creates life using methods which have a decent chance of naturally occurring, wouldn't that be evidence against creation. Where if it took more extraordinary and unnatural methods to create life wouldn't it be evidence in favor of creation?
Does that make transcription JIT compilation?
No kidding!!! What do you say at this point?
If this is just one (or even a few) step away from being alive, isn't this pretty stupid?
Lets just assume, for the sake of argument, that something happens that converts this from inert, but close to life, to actually alive, as must have happened at some point in the past (because we are here as proof, sorry creationists I don't buy your broken argument), then if this stuff become alive we have some serious potential problems.
What if this new protoplasm (for want of a better, more accurate word) is better in the antibiody/germ warmfare division that "life as we know it"? What then? We have no antibiodies for this stuff, neither does any other living creature. How do we defend ourselves?
Its not a case of this is organic life as we know if, but no antibidodies, but we can work on it, this is, we haven't a clue how to react to this, we can't work on it territory.
Yes, I guess in all liklihood w'll be OK. But what it, just what if, a combination occurs that is dangerous to us, what then? Well frankly we're screwed. People shouldn't be messing with this until they know what they are doing. Its more important that just curiosities sake. A lot more.
And finally, yes, I think its seriously impressive that someone has done this. But I don't think its clever at all. Different things entirely.
Are there still actually questions about Creationism?
I mean, beyond, "why do we still allow human beings to be to believe in Creationism?"
This here is nanomachine engineering. Arranging molecules. Making devices that perform certain functions.
If it's life-like, then yay, we can check that box, and get on to finding profitable uses for the technology.
The only places where it may raise "questions about creationism" is in Western society, and even then I would limit that to the most backward countries, or country. Most nations are too forward-thinking to permit their children to be allowed, in mass numbers, to be raised with such brainwashed, useless perceptions of the world.
No Nobel prize for you, Jack! We don't give awards for attempted chemistry, do we? Or punish people for attempted murder! Wait a minute...
Surely the OP doesn't believe that an intelligent being almost creating life is somehow threatening to those who believe life was created by an intelligent being?
Speaking of self replicating, I had sex last night with a supermodel (almost). Well, I guess that depends on what is meant by almost. Also, the definition of supermodel might be relevant here 8^)
Look where all this talking got us, baby.
If god is omnipotent, then god should be able to make something he cannot understand.
If god can, than god is not omniscient, because he would be able to understand it.
The same can be said in reverse.
Omnipotence and omniscience are mutually exclusive, thus a truly unlimited being is not possible.
VLC FOR MAC IS DYING! IF YOU DEVELOP, PLEASE SAVE IT!!
I have actually followed this labs work for some time. The simple truth is that the whole evolution/origin of life concept has a whole lot to do with probability. In fact there is a great argument for life owing much thanks to the moon for it's tidal forces and thus increasing of concentrations of substances in tidal pools. That being said probability of chemical change increases vastly with time and there was a whole lot of time before life arose. I do not think we can even fathem the amount of time to create life from scratch and we certainly will not do it. However, this offers understanding as to what steps were likely taken to reach where things are now.
... go down to the cemetery and fetch a brain for my creation.
Its pronounced "Eye-gore".
Have gnu, will travel.
"Men shouldn't play god!" "Can we play Spore, then?"
These guys aren't anywhere near making anything as complex as actual biological life. What they're doing is more like biological engineering than biology. TFA reports they are close to making a very simple self-replicating system...
it's important to note that this thing they haven't made yet wouldn't be able to self-replicate without 'help' from the researchers once they actually DO make it. Of course, down the road they would like to get something that could be autonomous, but even then it wouldn't be able to survive outside the lab.
From TFA:
and
So we're really far off from what you're speculating about...but, to address your concerns, alarmism about this research along the same lines as the people who are afraid that CERN will open a black hole that will swallow the earth (not saying you are alarmist...but some are).
Bottom line is, once they make a self-replicating artificial organism that can also exist outside the lab we should put it in the same level of quarantine that we give the nastiest of the nasty biochem. weapons or diseases we keep for research. It's not like we don't know how to safely work with dangerous substances/organisms.
Thank you Dave Raggett
This is just viral marketing for Spore.
That's pretty easy to answer, it's neither. It's a scientist creating life from scratch in a test tube. Abiogenesis is when there is no scientist involved.
Additionally, creationism is when God is required, so while it's not either, it does demonstrate that God is not required to form a living organism from non-living raw materials.
But tomorrow LHC will wipe it all out ... so I'm cool...
"some scary bio-research-gone-wild scenarios."
Nature is far better at producing far more and more diverse potentially lethal hazards far faster than all the bio-labs on the planet. Plus, nature has been at it for billions of years. If he could do it, nature probably already has, and we're still here.
Besides, if he builds something not related to Earth life, the possibility that it could affect Earth life is virtually nil.
I remember once there was a science related story on /. that didn't devolve into sCaRy mOnStEr sci-fi speculation. Once. It's amazing what mischief the mind can get up to when it's working with very little information, except no, it's not at all amazing.
"I may be synthetic, but I'm not stupid." -- Bishop 341-B
Whenever I start contemplating DNA (!), self-reproduction and the utter insanity of how complex the machinery of a single cell is, much less multicellular life, much less an animal, much less a self-aware brain, I just shake my head in wonder.
Doesn't bother me. Evolution is a massively parallel computation and has been going on for a LONG time.
If you skip DNA and just look at RNA it all gets easy:
- RNA caries genetic information and can be copied by an appropriate enzyme. (It's less stable than DNA, but quite stable enough to form the genomes of viruses. At the early stages, with no competition yet, being error-prone is actually good.)
- RNA has enzymatic activity. (It's not as strong or as versatile as protein-based enzymens. But it is quite capable of folding itself up into structures coded by its sequence, sticking together at appropriate places and presenting controlled patterns of charges on outer surfaces of a controlled shape, to become a little molecular machine.
Nucleotides line themselves up on a strand of either RNA or DNA to form the complimentary code sequence. They'll bind themselves into a strand given enough time and jostling. But if you have a RNA strand that also sometimes folds up into a little zipper-tab that runs down the lined-up RNA bases and sticks them together into a fresh strand you're all set:
- You'll eventually have both that and its compliment hanging around in the same container.
- At some point the strand that folds up into a zipper will zip up the new bases stuck to its complimentary strand. Then you have TWO zippers tab strands plus a complimentary strand.
- Now the zipper strand(s) start churning out new zipper strands and complimentary strands.
Slow at first, because rev 0.1 probably doesn't work well and it's completely dependent on randomly occurring bases for "food". But with the exponential under way the errors start to accumulate. Now you get some that are better at zipping than others - and they dominate the regions where they occur. And you get strands with multiple copies and other noise sequences - which can now evolve separately within the strand and evolve new functions.
Whenever a strand evolves one of its "spare" "genes" into a machine to help out, it becomes more successful.
From there you can evolve:
- Machines to make components of the system from other "useless" stuff.
- Machines to string amino-acids into useful structural stuff - and eventually better machines.
- Machines to control a container, creating the "cell" and its division mechanism.
- Machines to make backup copies of the RNA code in more stable DNA and then make more RNA from that.
and so on.
There's plenty of suggestions that this is what happened. For instance: Most of the machinery of RNA-directed protein synthesis - both most of the parts of the ribosome (the stringing factory) and all of the transfer RNA (the amino-acid carrier/code reader mechanisms) are RNA enzymes.
So, no, contemplating the current complexity doesn't bother me at all. It can all be explained by evolution from a single, simple, mechanism that could easily be produced in millions of years of random abiotic chemical reactions in a planetary scale vat of solar-irradiated, weather-stirred chemicals.
Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
I may have missed this bit, and the work is unpublished, but I read this article as saying this guy put chunks of RNA into a big fat glob, added water and saw the big fat glob break into smaller fat globs with bits of RNA in them. Is that not just a kitchen-sink-dishwater effect of division, not replication?
Why does this have to raise questions about Creationism?
I'm an atheist free-thinker, and even I know that Creationists do not have any questions.
They only have answers.
Just ask them.
Why can't we just keep this about science, learning and knowledge?
Just let people think what they want, Creationism, mysticism, voodooism, you'll never change the beliefs of the irrational, no matter how much hard science you come up with.
One of Carl Sagan's ideas was that a reason we might not see so many alien civilizations out there is because after reaching a certain level of technical proficiency, they would eventually blow themselves up with nuclear weapons.
Maybe biology running amok is more plausible. ...now here come the slashdot pedants who can't distinguish between fun speculation, a serious hypothesis, and a statement of fact.
god damn outsourcing
life always finds a way......
What questions? Like whether Creationists are really babbling on about some aliens creating life on Earth as some kind of "live action videogame" or something?
Or some ridiculous question about whether having a fabulous chemistry set makes someone a god, and science that dumb people understand equal to a bona fide "miracle"?
--
make install -not war
A living cell is profoundly more complicated than the lipid shell this individual designed. And then he takes already formed nucleic acids, that already have code invented and written upon them, and in the end, has has made the equivalent of a plastic box that he stuck pieces of a floppy disk in. Talk about hype!
"Having not been made by natural evolutionary forces..."
A dude in a lab is just as much a force of evolution and nature as a comet fueling a primorial soup or whatever you think triggered life on Earth. You don't GET to go outside the system. There is no unnatural .
When the researcher adds the next improvement to these globs of goo that allows them to survive better they will have evolved inside the system of nature which includes the petri dish they may someday live in.
And if it comes to pass that one day they evolve into a symbiotic arm for amputees or a blob that eats chicago, that will be natural as well.
"The Adobe Updater must update itself before it can check for updates. Would you like to update the Adobe Updater now?"
I'm not so astounded by the creation of life, but by the occurrence of the same kind of life in nature (and where) to tell us the chances that abiogenesis likely happened so long ago. Creating a man-made molecule in a collider and making life in a test tube are fun exercises, but I want reassurance that the world happened the way we have been teaching it (YMMV in Arkansas).
Often wrong but never in doubt.
I am Jack9.
Everyone knows me.
I'll take the random A+ high school biology student over a Wikipedia article. This is coming from interviewing people for a position at my business - you can see the Wikipedia in the resume and hear/feel it in their oral interviews. If you pay attention to Wikipedia, that is. I prefer free-thinking high school students to Wikipedia whores anyday.
Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
"As a Slashdot discussion on any scientific topic grows longer, the probability of it devolving into creationist-bashing fest approaches one."
Birds are warm blooded? Why dosen't anyone tell me these things!
"Persistance is Fertile" - Me. I can quote myself if I want to.
Not!
.... a Slashdot nerd almost had sex. Details at 11.
Evolved life wins.
We have had billions of years of self replicating machine eating each other for survival. What on earth do you think that they'll do to an organism which doesn't have that background?
Deleted
Then why are you commenting on the subject? It's called talking out of your ass. Please don't do it.
How many more years will slashdot have an off-by-one error on your Score in your profile?
...to start a company called Umbrella Corporation, this would be it :D
Machine9dotNet
which brings intelligent design really down to earth doesnt it ... God was not an alien ... but a geek ????? omfg, the truth must be close
beware he who denies you access to information for in his mind, he already deems himself to be your master (SMAC-ish)
Actually, nope, they're quite distinct cases, regardless of the "god" option. Something having a beginning does not automatically imply that it was "created" by something whatsoever.
E.g., there's a rainbow outside. It wasn't "created" by anything. It's just the interaction between a bunch of droplets of water, and the sunlight coming in at the right angle. Both are quite random things, and it seems funny to ascribe the power of creation to them. It's an ephemereal phenomenon.
E.g., the formation of the Earth and solar system that that. It's just a bunch of atoms and mollecules which collapsed under their own combined gravity, and happened to settle in this configuration. Some of them first accreted into smaller bits of stone and ice, but nevertheless it's just physics at work. It wasn't "created" by anything whatsoever. It was just a cloud which re-settled in another, more compact, shape under its own gravity. At best you could say that the solar system "created" itself.
Plus, as was already said, you're already postulating that time itself must have existed before the "beginning", which isn't necessarily a given. It's just another axis of the time-space of this universe. Just because we can mentally extrapolate beyond point zero, it doesn't mean it actually existed.
E.g., I can mentally extrapolate going a billion miles west of here. I mean, I can walk a mile or two in that direction, why not a billion? In reality, there is _no_ point that's a billion miles west of here, on this spheroid we call Earth. It wraps around.
E.g., heck, in the Universe itself, I can easily extrapolate something like "a trillion light years in that direction". In reality, there is no such point because the universe itself is finite.
E.g., I can come up with a mental extrapolation like "the 42'th planet around the Sun." I mean, their distancs and periods are just a number series. There's nothing in it that would prevent you from calculatin how far a 42'th planet would be, and what period it would have around the sun. But there is none. Just because you can calculate something it doesn't mean it actually exists.
Ditto here. Just because our intuition can extrapolate something, it doesn't mean it necessarily existed.
Heck, it may even be inaccurate to extrapolate to infinity in the _future_. There is at least one hypothesis based on string theory that there is no acceleration of the expansion of space, it's the time itself that is actually slowing down. And will eventually stop completely. So there might be a point T, past which there is no more future. Much as you can mentally extrapolate past it.
Etc.
Basically don't let your perceptions and intuitions run your model of the universe. Said perceptions and intuition were made to work at small distances, over limited times, and generally with small numbers. There are phenomena which happen too fast or too slow or over too large distances, to bear any relevance to how the mammal brain evolved to deal with or to even resemble anything that your first hand experience includes.
A polar bear is a cartesian bear after a coordinate transform.
Well, that any sane person would interpret you like you did, is fairly obvious. Now try telling it to some of the bible-belt bible-thumpers. Last I've read some of their arguments, it boiled down to exactly that:
- evolution can't possibly happen, a dog will never evolve into a cat
- life is too complicated to have appeared by chance, it's only God / The Intelligent Designer who could have made it
- certain organs are too complicated to have appeared by random mutations and natural selection, only God / The Intelligent Designer who could have made them
Etc.
Heck, there even was this recent experiment where a bacteria culture held on a citrate substrate, which it originally couldn't metabolize, eventually evolved the proteins to take it apart and feed on it. A certain group of bible thumpers outright accused him of fraud.
Again, I'm not saying that _all_ christians are like that, or that the bible is like that. But there _are_ people who interpret it just like that: _only_ God could have created life.
A polar bear is a cartesian bear after a coordinate transform.
Mansy SS, Schrum JP, Krishnamurthy M, Tobé S, Treco DA, Szostak JW. Template-directed synthesis of a genetic polymer in a model protocell. Nature. Published online 4 June 2008(PDF warning). Does not require subscription to Nature, because it's straight from his lab page.
I do not believe in karma. "Funny"=-6. Do good and forbid evil. Yours, Oft-Offtopic Flamebaiting Troll.
From abstract:
Here we show that such membranes allow the passage of charged molecules such as nucleotides, so that activated nucleotides added to the outside of a model protocell spontaneously cross the membrane and take part in efficient template copying in the protocell interior. The permeability properties of prebiotically plausible membranes suggest that primitive protocells could have acquired complex nutrients from their environment in the absence of any macromolecular transport machinery; that is, they could have been obligate heterotrophs.
I do not believe in karma. "Funny"=-6. Do good and forbid evil. Yours, Oft-Offtopic Flamebaiting Troll.
So far his lab created membrane bubbles that suck in the nucleotides. Inside those bubbles they had primer-template complexes like:
5'-GATTACA-3'
3'-CTAATGCGATGCCGTAGATC...-5'
Once inside the bubble the nucleotides spontaneously build up at the end of GATTACA... primer (primers are actually longer, 15 bases) complementing template. The proof of that is seen in gel electrophoresis pictures on Fig 4 of the original article in Nature(PDF).
The article is pretty readable, btw.
I do not believe in karma. "Funny"=-6. Do good and forbid evil. Yours, Oft-Offtopic Flamebaiting Troll.
Since when were high school students 'free thinking'? At least the ones reading wikipedia are actively searching out information rather than only learning it because they have to. Yeah, I just watched Good Will Hunting for the first time last week ;) While the story is pretty exaggerated it has some truth. I didn't learn anything at university that I didn't already know, or couldn't have just learned by reading a textbook. Seriously. I was in fact much more interested in learning before I went to university, but part of that was just personal circumstances. I spent a lot of time during high school doing coding in my spare time, but since I had to start doing it for coursework/my job I just want to relax in my spare time..
If by a wikipedia whore you mean someone who will only have a cursory glance at the subject and not look into it in any further detail, then I agree though.
For something as nebulous as the definition of 'life' though, you could start in worse places than wikipedia for seeing a few different opinions. I'm seeing a lot of yahoo question and answer sessions whenever I google for info these days, and some of the answers are atrociously wrong, though presented in such a way as to try and sound like the person knows what they're talking about.
which is totally what she said
what is there to question about creationism? its not science. in fact, its right up there with scientology as far as im concerned.
heck, opening a can of beans does just as much to call creationism into question as this scientist.
Good people go to bed earlier.
Wasn't this the one where captain Oneal goes and tells everyone that bringing the replicators on board is a bad, ...very bad idea....and no one listens, and then the whole ship is taken over.
Or no wait, wasn't this the episode where Scotty brought on one of those little cute furry things on the enterprise and by the end of the episode, they were falling out of the vents and the ceiling and the walls....
Yeah I think that's it....
Does artificial mean "assembled by people" or "not real/authentic"?
If this biologist combine a dash of this and dash of that and life arises, is that artificial? The molecules are just doing what they are supposed to do. If you throw sodium metal into water, it's quite natural for there to be an explosion, even though it was a person getting the whole thing started.
My gf is a geophysicist and she tells me there's no such thing as an artificial diamond. If it was created in a lab, it's a carbon crystal. Diamonds are minerals, minerals come from the ground, not labs. The two materials are chemically identical.
i'm not trying to make either case, just musing on what we mean by artificial.
Utilizing the synergization of benchmark e-solutions to pre-workaround action items!
I, for one, welcome our new protoculture overlords.
Is there a "-1, Duh" moderation? Of course plants/chlorophyll harvest solar energy, but that wasn't the question.
What I was asking was: can we create an organism that produces usable electrical or biolmechanical energy (other than as petroleum-type fuels).
I don't get the connection between artificial life created in a laboratory and creationism...
However, this does seem to lend some credence to the theory of inteligent design...
"In The Structure of Scientific Revolutions (SSR) Kuhn argued that science does not progress via a linear accumulation of new knowledge, but undergoes periodic revolutions, also called "paradigm shifts" (although he did not coin the phrase),[2] in which the nature of scientific inquiry within a particular field is abruptly transformed. In general, science is broken up into three distinct stages. Prescience, which lacks a central paradigm, comes first. This is followed by "normal science", when scientists attempt to enlarge the central paradigm by "puzzle-solving". Thus, the failure of a result to conform to the paradigm is seen not as refuting the paradigm, but as the mistake of the researcher, contra Popper's refutability criterion. As anomalous results build up, science reaches a crisis, at which point a new paradigm, which subsumes the old results along with the anomalous results into one framework, is accepted. This is termed revolutionary science."
My point here is that scientist are constantly directed in two ways 1) to enhance and confirm existing hypothesis's and 2) refute the existing hypothesis's, sometimes utilizing techniques which extend outside the relevant and 'reliable' realm of science.
...very close to satisfying the conditions for being 'alive'
That's the same thing my wife says about me. Hey, I'm a science experiment!
You never really know how close to the edge you can go until you fall off.
Thats unfortunate; I didn't learn anything I didn't know already when i was taking classes in high school. College is where things got interesting and challenging. Coding in class has made coding outside of class a lot more exciting.
College provides such a thorough explanation of subjects. Reading a wikipedia article on linear algebra or the antebellum south or ionic chemistry is nothing to the absolute immersion demanded by college courses in the same subject. Forcing yourself to read a textbook because of an intimidating exam is also a great way to learn;unlike will hunting most people will not fully grasp something they study only casual esp. at such a young age.
... welcome our new blubbery overlord.
What I'd like to know is: What did the first living cells eat? The Earth would have been starel(sp) before there was life. Life eats life.
Plus, how long did those early cells live? Was there so much life popping up that it was ok that the cells only lived a few days? I just don't see how a single cell could live long enough to evolve into anything other then it's original form. It would have to be randomly created with the ability to reproduce asexually in order to pass on it's dna to future generations.
"That's so plausible, I can't believe it!" - Leela
Constructing something that can hijack some or all of a life form is no doubt impressive, but ultimately no more than a virus. And is that creating life? I certainly don't think so, any more than putting some robotic exo-skeleton on a soldier will be creating a human being.
=-+
Pshhh.... I was going to create life, too but instead I just stayed home and played Spore.
Steal my band's record! Seriously,
I have been extremely close to being a billionaire for about 30 years now.
I guess that isn't real news either?
Athiesm is a religion like not collecting stamps is a hobby.
Thats unfortunate; I didn't learn anything I didn't know already when i was taking classes in high school.
I find that very strange - I learned plenty about geography, physics, chemistry, german and even some Maths in high school. For stuff like Computing, Music and English I didn't learn that much that I didn't know, but I certainly learned some things.
When it came to university I perhaps learned a little about interface design, databases, a bit of logic/set theory etc (though I'll admit I've forgotten some stuff like the logical notation). I did find some of these classes interesting but due to personal circumstances like I said (depression due to my dad dying, and he was the one that got me interested in computers and taught me a lot of stuff about coding) I wasn't very well motivated at Uni. Since I started off basically knowing everything for the first 2 years and getting good grades without even trying, the classes in 3rd and 4th year hit me a bit harder because they were starting to cover things I'd never studied before, but I was already in a pattern of not really going to classes or studying. I actually ended up having to read an AI textbook to pass one of my exams in 3rd year! It was the first exam I'd ever failed. Usually I could get by just by reviewing the lecture slides for a day or 2 before an exam. I basically already knew the first half of the content of that class (probably was stuff like graphs, which I knew about because I'd written pathfinding algorithms for my Counter-Strike bots in high school), and so had stopped going to the lectures, but it turns out the second half was stuff I'd never done before :p
I don't find exams intimidating, I rather enjoy them actually. Theory exams anyway. You have time to think in a nice quiet atmosphere, and you can erase mistakes. Practical tests such as driving tests get me pretty nervous, but I passed my advanced driving test earlier this year, so a normal test would probably be piss easy for me now.
which is totally what she said
Unfortunately, that's only ADHD talking, and I have been guilty of it too. I too used to essentially divide the world into, essentially,
A) stuff i would have learned on myself anyway, and
B) stuff which, OMG, is so unimportant and only some oppressive way to waste my time.
Even if you don't explicitly do that dichotomy in your message, I think that _must_ be the underlying aspect of it. Or are you telling me that you would have also learned Geography, History, Chemistry, Biology and read the classics of literature on your own?
Unfortunately there's a lot of stuff you might (or might not) end up needing later, but you don't know that yet.
As a trivial example, someone who thoroughly understands maths, will have the upper hand in a lot of programming domains, over someone whose only learning was teaching himself (the worst habits of) programming on his dad's C64. I'm not even saying I'm the best example there, because honestly maths was outside my focus of interest at the time, but I grudgingly learned it anyway because even I realized I needed it for physics, which was my main interest in school. But anyway, later I stumbled into programming 3D graphics stuff, and suddenly that maths was actually useful. Just telling someone stuff like "imagine a line in six dimensions" when explaining texturing, and watching him go cross eyed because he lacks the mathematical understanding even for that, is the kind of thing I'm talking about.
Or I see people all the time (and often am brought as a consultant to polish their turd) who spend inordinate amounts of time debuging Java's HashMap, and going "OMG, Java is broken! It replaced my old value with a new one whose key has the same hash value!" and maybe even coding comically absurd "workaround" that are trivial to prove that they can't possibly work. When in reality Java just added a new node to the front of the linked list for that bucket. But they don't really know how a hash table or even a linked list actually work. They too thought they don't need a college teaching them that, and when it bites them in the arse, they just don't know what's happening there.
Or I see people who don't even understand the O notation, and why their O(n*n) algorithm may work well on their 10 records test case, but is going to grind to a halt when fed the two billion records of their production database. (And that's actually a pretty small one.) Or I've spent an hour in a meeting explaining to someone (he's been promoted to architech nowadays, btw;) that, yes, in a table of key/value pairs you can store more than two values. Yes, that table has only two columns (ok, three including the parent ID), but you can still store more than two values in there. He obviously wasn't mentally equipped to deal with key/value pairs.
Now I'm not saying that you're of the same calibre. Some people did learn those concepts on their own. But a lot didn't.
That's basically my point. The attitude that you can just teach yourself everything by just banging on your dad's computer's keyboard, might actually leave holes that you're not even aware of. For some people, it's even the basics of the job they end up in. For others, it's just something which would have come in handy later. The ones who'd really learn everything they need on their own, are, in my experience, far and few in between.
A polar bear is a cartesian bear after a coordinate transform.
Wikipedia is routinely considered to be an excellent aggregator of references in fields where references mean something. (You know, down at the bottom in the "references" and "external links" areas?)
The long and short of it turns out to be: Using Wikipedia as a reference in a hard discipline: bad. Using it as a jumping off point: Good.
Btw, A+ biology students in high school are just regurgitating facts (perhaps gained by carefully structured "experiments"), so they're probably only "on par" with "wikipedia whores".
of the creation of the dread penis monster.
I am Bennett Haselton! I am Bennett Haselton!
New Forms of Intelligent Life will be created in a Computer Lab!
The future is going to be interesting.
Tsukasa: All I really want, is to be left alone...
I almost solved world hunger, brought peace to the Middle East, solved the gas crisis.. I think you get my point.. when was "almost" news worthy? BTW> I *DID* post this ;)
I was always hoping to hear about this once, that life was fully created in a laboratory repeating natural processes that started it in the first place. This is closest yet to my hopes coming true.
My other hope is that people stop electing politicians into the office who deny such natural occurrences and base their policies on their religions and other superstitions.
Well one can hope.
You can't handle the truth.
Actually these type of sythetic life forms have already been shaped by evolutionary forces. I think it is wrong to think of this new life forms, they are more like biological hacking together a life form, from genes already known.
Even the genes that are artificially designed and built are done so from the knowledge already gain from the study of genetics/protometrics. Its a bit like mixing and matching engine and car parts, to get something that runs.
Still if you believe that this idea would still constitute artificial Life then in essense its already been created by the J. Craig Venter Institute with Mycoplasma laboratorium & Phi X 174. http://en.wikipedia.org/wiki/Synthetic_biology
Which have been built with safeguards (e.g., a suicide gene) to stop it from surviving outside a secured lab. By design most of these initiatives are commerical ventures (think synthetic oil/fuel), so while some genetic code has been released - its the techniques and the genetic databases that are the money spinners.
We still use that [simplistic] kind of language today in everyday conversations.
Most people aren't scientists by trade, and most people have underdeveloped critical thinking skills. Lay speech is only good for conveying lay thoughts.
God says[you mean "people, who claim to write on behalf of such a god, say"] that we are made of the dust of the ground.
That the plants and creatures living on the earth incorporate* constituents of the earth into their bodies is a trivial observation. This is obvious to any creature of human-level intelligence, and probably predates (and is perhaps pre- or co-requisite with) the dawn of agriculture. Some pre-scientific authors' noticing the fact is deeply mundane and unimpressive.
* Seguing nicely into my next point about language: the word incorporate has Latin corpus as its basis. Its literal meaning is to make something part of the body.
We still talk about sunrises and sunsets, even though science has since shown that this is an illusion created by the rotation of the Earth.
This and other similar examples are artifacts of language. Many counterintuitive properties of nature have been discovered very recently compared to the time it takes any language to thoroughly differentiate from its past form. In this example, even a very easy change hasn't been made because the incorrect lay expression is good enough for most people and their purposes.
[we] think of ourselves so knowledgeable compared to those ignoramuses who lived a long time ago.
We are. We've learned more in the last 400 years than in all prior history; we've learned more in the last 50 years than in all prior history. Those are the facts, and admitting as much is not arrogance, but frankness. Denying as much is servility and false humility.
So this language was designed to be understood by the ancients as well as us...
What a worthless claim. Of course people in the future can understand a thing known in the past; understanding increases over time! The concepts in Newton's Principia have been greatly expanded upon since they were first "understood".
And please don't put sentiments into people's mouths; people aren't as haughty as you would have your readers believe. It's not that our ancient ancestors were savages to which we have some right to feel superior; they just didn't know much about the way nature behaves, because comparatively little work had been done to figure it out. "Ignoramus" connotes "buffoon", and it's shady of you to imply that modern, intelligent people think their ancestors' lack of knowledge makes them worthy of scorn.
In the book of Job...the Creator God [gave] Job a science quiz.
Rubbish. The purpose of this passage was to illustrate to Job his lack of knowledge; not test his knowledge, nor his problem-solving ability, nor to educate him. The authors had no knowledge of how these "questions" could be answered and probably considered them beyond answering. They revealed no knowledge unavailable at the time they were written.
Job flunked.
The authors meant for him to look foolish in this story, and indeed they couldn't have imagined how anyone could possess such understanding. The weakness of their examples in light of two millennia of human discovery is telling.
Modern scientist given this test might be lucky to barely get a "D".
With this false claim you show yourself as an ignorant non-scientist bent on understanding every facet of human nature and the vast universe through the lens of a bronze age manuscript. "After all," your thought process goes, "the holy book that happened to be prevalent in the land I was raised in is a perfect record of fact beyond even the slightest doubt. All understanding that can be twisted to fit its framework will be, an
The phrase "charging elephant" springs to mind.
Eric Baird