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Possible Breakthroughs in Cancer and AIDS Research

FortKnox writes "Two possible medical breakthroughs have come to light in recent days. In Australia, it was discovered that pineapple extract can stimulate the body to attack cancer cells. And in Japan, Kumamoto University researchers have developed a drug that will block cells from the AIDS virus, thus making something akin to an AIDS vaccine." From the Australian news: "One of the molecules, CCZ, stimulates the body's immune system to target and kill cancer cells, the other, CCS, blocks a protein called Ras, which is defective in 30 percent of all cancers. QIMR researcher Tracey Mynott said her team had set out to find why the enzyme-rich bromelaine crush had such strong effects on biological material."

403 comments

  1. Still no cure for cancer... by Anonymous Coward · · Score: 5, Funny

    Still no cure for can...er, never mind. Well, the people over at FARK must be really disappointed. They'll have to come up with a new tagline!

    1. Re:Still no cure for cancer... by Aqua+OS+X · · Score: 3, Funny

      Dude, what are you talking about. According to Slashdot, cancer and AIDs are cured every other month.

      --
      "Things are more moderner than before- bigger, and yet smaller- it's computers-- San Dimas High School football RULES!"
    2. Re:Still no cure for cancer... by Anonymous Coward · · Score: 2, Insightful

      A cure for AIDs has existed for quite some time, it's called abstinence (probably not a difficult thing for most of the geeks here).

      AIDs can spread through shared needles and blood transfusions, but predominately it is contracted from unsafe sex. Rather than worrying about a cure, stop the infection to start.

    3. Re:Still no cure for cancer... by Anonymous Coward · · Score: 0

      Even more amazing, in the months AIDS and cancer are cured, they get cured TWICE!

    4. Re:Still no cure for cancer... by Ced_Ex · · Score: 2, Funny

      Abstinence... the boring cure for AIDS.

      I, for one would welcome the return of free love of the 60s and 70s with the vaccine.

      --
      Live forever, or die trying.
    5. Re:Still no cure for cancer... by Shalda · · Score: 1

      In other news, Duke sucks.
      Your dog wants steak.
      FDA surrenders.
      Some famous cancer patient unavailable for comment.

      I'm sure they'll get along just fine. Cancer is still a long ways from being cured, and once it is, that just means more Boobies links. Won't someone please think of the kittens?

    6. Re:Still no cure for cancer... by JhohannaVH · · Score: 1

      Hell yeah!! Imagine the peace the world would have if they would do that and legalize marijuana... for medicinal purposes of course. Our parents wanted to save the world! Why can't we? :P

      --
      Sorry man... the Internet pooped on me.
    7. Re:Still no cure for cancer... by FirstTimeCaller · · Score: 2, Funny

      According to Slashdot, cancer and AIDs are cured every other month.

      And probably again tomorrow when this story gets dup'ed.

      --
      Wanted: witty unique signature. Must be willing to relocate.
    8. Re:Still no cure for cancer... by CharAznable · · Score: 1

      PUH leeeese! Asking people to stop having sex is like.. asking people to stop having sex!

      --
      The perfect sig is a lot like silence, only louder
    9. Re:Still no cure for cancer... by DanThe1Man · · Score: 1

      I just want to comment on your .sig.

      I'm a hard core liberterian, but I think he said it that way on purpose. If he would have said "shame on me" you know that sound byte would have been repalyed over and over again with the war and all. Just him cliped out saying "shame on me". He probably saw that comeing and decided not to say it.

    10. Re:Still no cure for cancer... by Anonymous Coward · · Score: 0
      What are "AIDs"?

      It's AIDS: Acquired Immune Deficiency Syndrome.

    11. Re:Still no cure for cancer... by surprise_audit · · Score: 1
      According to Slashdot, cancer and AIDs are cured every other month.

      And sometimes twice in the same week, if the editors are bored or not paying attention...

    12. Re:Still no cure for cancer... by Anonymous Coward · · Score: 0

      Fellas, I dunno... I just hope this shit gets cured period!

      I saw an uncle of mine (other side of family by marriage) die a long & protracted death by cancer of his digestive tract... it was horrible. Worst part? He was one hell of a guy!

      ON AIDS?

      Well, I've seen 2 guys I know in my life (both 'straight' not gays) get it and go from 225lbs. of solid muscle on one fellow, down to 100 or less lbs. and wither like a rose... it was awful. This guys had EVERYTHING going for him too:

      1.) Good looks

      2.) Good job

      3.) Wealthy & GOOD family behind him

      Was sad... & such a waste.

      The other guy, a really good friend of mine for decades, was to put it bluntly?

      WAY too "promiscuous", and ended up with it...

      (I mean, I admire a guy that "gets it alot", but not @ THAT price).

      He died @ 32 years of age... that's not even what? 1/3 of your total life expectancy nowadays??

      Talk about a waste, because this 2nd dude was one of my best friends too, and a RIOT to hang out with!

      All I know is, cancer is terrible, so is AIDS, but AIDS? Is messing up the social scene, & BAD!

      (Genital Herpes too).

      I dunno about YOU guys, but I come outta the 80's & you got laid every nite by diff. women if you liked...

      HOWEVER, nowadays?

      Everyone's SO damn scared of Herpes (which rumor I heard is like 1/3 or more of the U.S. population has now, & when I see "Valtrex" commercials on T.V. like I have for a year or two now? It's probably NOT inaccurate!)?

      Nobodies 'getting any' or like they used to imo, & experience. It's screwing up the natural order imo.

      ALSO, imo, on statistics?

      If they say, e.g.-> 1/3 of U.S. population has it?

      You can double that imo!

      After all, It progresses geometrically, & condoms DO NOT STOP catching herpes... & they cannot test everyone after all, & can only make guesses (plus, I am a pessimist about things like this).

      These freaking "Terrors" have messed up MY 'social life' so-to-speak!

      Not only MINE, but, my pals also who do not have steady girlfriends or wives!

      In fact, we all talked about it the other nite @ a cardgame we have @ times here and there:

      Nailing babes in the mid to late 90's & the 21st century?

      Isn't as SIMPLE/EASY as it used to be...

      (AND, not just because I'm older (because I chase older women anyhow who are nearer my age than 21 year olds, they look like kids to me & are not independent either... I hate dealing with "Mom & especially DAD here" lol,) but because of these threats!

      It'll be a GREAT DAY of celebration imo, once those are cured...?

      Heh, guess what the first things I will be out to look for & do then, lol? AND, don't tell me you won't be either!

      * It'll be one HELL of a party imo, on that day!

      APK

    13. Re:Still no cure for cancer... by Aqua+OS+X · · Score: 1

      http://politicalhumor.about.com/library/multimedia /foolbush.mov

      What ever it was... it sounded retarded. ;)

      --
      "Things are more moderner than before- bigger, and yet smaller- it's computers-- San Dimas High School football RULES!"
  2. Vindicated! by TripMaster+Monkey · · Score: 3, Funny

    From TFA:
    Australian scientists have discovered pineapple molecules can act as powerful anti-cancer agents and said the research could lead to a new class of cancer-fighting drugs.
    Scientists at the Queensland Institute of Medical Research (QIMR) said their work centred on two molecules from bromelaine, an extract derived from crushed pineapple stems that is used to tenderise meat, clarify beers and tan hides.
    HA! I told my guidance counselor that all that beer drinkin' would pay off eventually... ^_^
    --
    ____

    ~ |rip/\/\aster /\/\onkey

    1. Re:Vindicated! by RapmasterT · · Score: 5, Funny
      dammit! I only drink cloudy beers.

      I guess it's going to be a long weekend of explaing WTF is up with the pinapples slices in my hefeweizen.

    2. Re:Vindicated! by Alex+P+Keaton+in+da · · Score: 1

      Actually.... Ex-snip-it A your honor....
      Circumcision may offer Africa AIDS hope Procedure linked to much lower rate of new HIV infections http://www.sfgate.com/cgi-bin/article.cgi?file=/c/ a/2005/07/06/MNGANDJFVK1.DTL&type=printableL
      Actually pinapple has another effect, that of making your bodily secretions smell/taste better. That is an old date trick....

      --
      And All I Ask is a Tall Ship And a Star to Steer Her By
    3. Re:Vindicated! by Bob+Cat+-+NYMPHS · · Score: 1

      Perhaps the fact that Muslims are the most likely to be circumcised is the reason for the low HIV rate. Religious prohibitions against casual sex may be the most effective tactic.

      I'm an atheist, fwiw.

    4. Re:Vindicated! by jeblucas · · Score: 2, Funny
      dammit! I only drink cloudy beers. I guess it's going to be a long weekend of explaing WTF is up with the pinapples slices in my hefeweizen.
      VWOOOOOOOOOOOOSH!

      ...that's what I heard when your comment went over my head.

      --
      blarg.
    5. Re:Vindicated! by Anonymous Coward · · Score: 0

      _________
      You Fail I|

      Lameness filter encountered. Post aborted!

    6. Re:Vindicated! by RapmasterT · · Score: 5, Funny
      Actually pinapple has another effect, that of making your bodily secretions smell/taste better. That is an old date trick....
      Considering at what point of the evening this "date trick" would become relevant, I've never understood why I should give a rat.

      My reaction to the statement "eewweee it tasts yucky" is usually "why are you still here"?

    7. Re:Vindicated! by gstoddart · · Score: 1
      dammit! I only drink cloudy beers.

      I guess it's going to be a long weekend of explaing WTF is up with the pinapples slices in my hefeweizen.

      Actually, a wheat beer is known to enjoy a little bit of citrus floating in it. I've had several varieties of wheat beer which the manufacturer reccomended some orange in it.

      But, at least then you can have the fun of ordering a pintofpineappleweizen. :-P
      --
      Lost at C:>. Found at C.
    8. Re:Vindicated! by LordKazan · · Score: 2, Interesting

      circumcision makes you more likely to contract STDs - contrary to urban mythology which was created by individuals whom falsified studies. The prepuce contains special immune system cells which secret an antimicrobial not to mention the prepuce contains 60% of the nerve cells, provides proper mechanical function (80% of incidents of 'painful coitus' for the woman is because of her partner being circumcised) I could go on.

      --
      If you cannot keep politics out of your moderation remove yourself from the Mod Lottery.. NOW!
    9. Re:Vindicated! by MajorDick · · Score: 2, Interesting

      It also fixes ruptured disks,

      Years ago I had a screwed up disk , oddly in between my shoulder blades , I dont remeber the number, It was the result or rotating with a 50 lb wrench in my hand around a ladder to catch myself from falling

      Sugery was the only option, then a doctor at Cleveland Clinic said they were doing trials with an enzyme extracted from papaya, the idea was they would "tenderize" the disk and manipulate it back in to shape and 48 hrs later the softeing effects would wear off and the disk would become firm over the next several weeks

      Better than surgery and it worked 100%, the worst part , (other than the BIG scarry needle with "Aldofs" Meat tenderizer as the doctor joked was being put in "traction" for some 48 hrs after so it could firm up agian

    10. Re:Vindicated! by dwntwnboi · · Score: 1

      hefeveizen, to my knowledge, is a very yummy wheat beer (as opposed to barley).

      personally, though, i prefer pennweizen, a type of hefeweizen, if i'm not mistaken--- although they could be the same beer. yummy, pinepple slice or not.

    11. Re:Vindicated! by RapmasterT · · Score: 1
      Actually, a wheat beer is known to enjoy a little bit of citrus floating in it. I've had several varieties of wheat beer which the manufacturer reccomended some orange in it.
      While the beer may enjoy it, I do not, and it irritates me to have to tell bartenders to keep the fruit out of my beer.

      My opinion is that if a beer needs me to add something to it to make it better, I'm just going to drink a better beer.

    12. Re:Vindicated! by gstoddart · · Score: 1
      While the beer may enjoy it, I do not, and it irritates me to have to tell bartenders to keep the fruit out of my beer.

      Ummmm ... are run-by-fruitings of your beer common where you are? I don't recall it ever being a problem.

      Except for Corona, I've never seen beer arrive with fruit in it by default. I can see how it would be anoying if you didn't want it.
      My opinion is that if a beer needs me to add something to it to make it better, I'm just going to drink a better beer.

      Well depending on how you look at it, you could be making a really-good beer even better.
      --
      Lost at C:>. Found at C.
    13. Re:Vindicated! by PsiPsiStar · · Score: 1

      I suppose it means you could use the line; "Do you know that if a guy eats enough pineapple, his jizz tastes like a pina colada."

      If she denies it, then she's obviously gone down on a pineapple eating guy before and you can tease her about that.

      "Mary told me that if you go down on a guy who's been eating pineapples it doesn't really make him taste any different..." etc.

      If not, just tell her you'll prove it to her later on.

      --

      ___
      It's the end of my comment as I know it and I feel fine.
    14. Re:Vindicated! by blincoln · · Score: 1

      (80% of incidents of 'painful coitus' for the woman is because of her partner being circumcised)

      How fortunate that a wide variety of cheap and readily available solutions to this potential problem exist.

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    15. Re:Vindicated! by onkelonkel · · Score: 1

      There is a wicked funny hefeweizen ad playing on the radio here. The voiceover says "We asked our German Brewmaster what he thought about people putting a lemon wedge in the hefeweizen" Next you hear this 30 second long explosion of red-faced screaming Teutonic rage and disgust "Eine Zitronenscheibe! Das darf doch nicht wahr sein! Unmoglich! IDIOTEN. SPINNER....."

      --
      None of them can see the clouds; The polished wings don't care.
    16. Re:Vindicated! by Miaowara_Tomokato · · Score: 1

      I could go on.

      And that continuation would be just as reliable as any other statistical reporting without citation.

    17. Re:Vindicated! by LordKazan · · Score: 1

      Source: NOHARMM, which is citing medical studies http://www.noharmm.org/advantage.htm

      --
      If you cannot keep politics out of your moderation remove yourself from the Mod Lottery.. NOW!
    18. Re:Vindicated! by dabigpaybackski · · Score: 1

      Dude, you forgot the umlaut.

      --
      "OH SHIT, THERE'S A HORSE IN THE HOSPITAL!"
    19. Re:Vindicated! by d34thm0nk3y · · Score: 1

      VWOOOOOOOOOOOOSH!
      ...that's what I heard when your comment went over my head.


      Clarify just means "to make clear". With beer you are basically settling out any sediments in the liquid.

    20. Re:Vindicated! by Anonymous Coward · · Score: 0

      You meant to reply to the original circumcision post, I believe.

    21. Re:Vindicated! by michrech · · Score: 1

      How fortunate for those who still have their foreskins that they:

      1) Don't have to purchase all that crap
      2) Have all the feeling they were intended to have so as to not have to pound the hell out of their date to 'get off'

      Yea, I think that'd be better than being butchered.

      --
      telnet://sinep.gotdns.com -- TW2002 and LORD registered!

      --
      bork bork bork!
    22. Re:Vindicated! by blincoln · · Score: 1

      I don't know any uncircumcised guys myself, but the girls I've talked to who've had sex with ones who are haven't said there was any significant difference other than the visual one.

      Is there anyone on here who was circumcised as an adult that can provide some perspective?

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    23. Re:Vindicated! by michrech · · Score: 1

      I wasn't butchered as an "adult", but I was when I was in a period of my life where I discovered sex.

      The feeling has definatly changed for the worse. It's an evil and barbaric practice that needs to end except in extreme cases.

      --
      telnet://sinep.gotdns.com -- TW2002 and LORD registered!

      --
      bork bork bork!
    24. Re:Vindicated! by ManiaX+Killerian · · Score: 1

      For the love of god (of the servers) don't put lemon in your drinks. It helps you consume more thatn you're used to, and then it suddenly hits you like the famous piece of lemon tied to a golden brick ... Especially bock beer with lemon is really deadly.

    25. Re:Vindicated! by BerntB · · Score: 1
      My reaction to the statement "eewweee it tasts yucky" is usually "why are you still here"?
      (-:
      Hmm... I would guess that guy is even older than me. Or drinks too much.

      Or he needs to buy some famous blue pills that have become popular the last few years.
      :-)

      --
      Karma: Excellent (My Karma? I wish...:-( )
    26. Re:Vindicated! by Anonymous Coward · · Score: 0

      Haha. Awesome.

    27. Re:Vindicated! by blincoln · · Score: 1

      I wasn't butchered as an "adult", but I was when I was in a period of my life where I discovered sex.

      Would you mind elaborating as to why you had surgery? I'm genuinely curious, since I'm not aware of any reasons for adult circumcision.

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    28. Re:Vindicated! by Anonymous Coward · · Score: 0

      The normal foreskin is soft and moist, just like the external female equipment.

      My girlfriend told me that, after I pointed out my circumcision scar to her, she never realized what that was. Even circumcised guys don't realize what that dark ring is.

      No jokes about my girlfriend's 'experience', please, at least I have one, you lonely /.ers.

      Also, she says my penis is beautiful, and will get me a beer if I become thirsty during a blowjob. And she swallows. ;)

      Did I mention the butt sex?

    29. Re:Vindicated! by MyLongNickName · · Score: 1

      My reaction to the statement "eewweee it tasts yucky" is usually "why are you still here"?

      And her reaction is: "Because I live here... I am you sister after all!" ;)

      --
      See my journal for slashdot ID's by year. Mine created in 2005. http://slashdot.org/journal/289875/slashdot-ids-by-year
    30. Re:Vindicated! by RapmasterT · · Score: 1
      And her reaction is: "Because I live here... I am you sister after all!" ;)
      (cue "dueling banjos" in the background)

      I didn't know they got Slashdot out in the Bayou...

  3. Enzyme-rich bromelaine crush? by Ossifer · · Score: 5, Funny

    Never tried it, but I do like Orange Crush...

    1. Re:Enzyme-rich bromelaine crush? by mpathetiq · · Score: 0, Offtopic

      Not only did you beat me to this joke, your ID is also 3 lower than mine. I'm constantly on your coattails, Ossifer!

    2. Re:Enzyme-rich bromelaine crush? by pizzaman100 · · Score: 1
      Never tried it, but I do like Orange Crush...

      Mix it with pineapple extract and you can have a Hawaiian Punch!

    3. Re:Enzyme-rich bromelaine crush? by OverlordQ · · Score: 0, Offtopic

      Not only did you beat me to this joke, your ID is also 3 lower than mine. I'm constantly on your coattails, Ossifer!

      (726625) - (703813) != 3

      --
      Your hair look like poop, Bob! - Wanker.
    4. Re:Enzyme-rich bromelaine crush? by Anonymous Coward · · Score: 0

      +726625
      -703813
      =022812=3?

      am I missing a joke here?

    5. Re:Enzyme-rich bromelaine crush? by mpathetiq · · Score: 0, Offtopic

      Sweet. Message Number != Slashdot ID. Yet another reason to avoid posting on less than a full night of sleep.

    6. Re:Enzyme-rich bromelaine crush? by ShyGuy91284 · · Score: 1

      I for one prefer Live Wire.... Tangier of a taste....

      --
      In undeveloped countries, the consumer controls the market. In capitalist America, the market controls you.
    7. Re:Enzyme-rich bromelaine crush? by pizen · · Score: 0, Offtopic

      You mean he posted before you AND the message number was lower? What are the chances?

      You don't need more sleep, just more coffee.

    8. Re:Enzyme-rich bromelaine crush? by TripMaster+Monkey · · Score: 1, Offtopic


      He must be counting in base 7604.

      Clearly, he is one of the Great Old Ones.

      --
      ____

      ~ |rip/\/\aster /\/\onkey

    9. Re:Enzyme-rich bromelaine crush? by mpathetiq · · Score: 1

      It's shocking how chronological numbering works.

      I don't think a coffee in the afternoon sounds good at all... maybe a nice iced chai.

    10. Re:Enzyme-rich bromelaine crush? by X0563511 · · Score: 1

      Er, the message number isn't 3 behind either...

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    11. Re:Enzyme-rich bromelaine crush? by mpathetiq · · Score: 1

      Sure it is. Look down, down, down.

    12. Re:Enzyme-rich bromelaine crush? by Ossifer · · Score: 1

      Coffee?!? Chai?!?

      It clear you just near a big tall Enzyme-rich bromelaine crush!

    13. Re:Enzyme-rich bromelaine crush? by Anonymous Coward · · Score: 0

      bromelaine crush != brominated vegetable oil (read your Orange Crush can)

  4. Mmmmmm... by mpathetiq · · Score: 0, Redundant

    Bromelaine Crush is so much better than Orange Crush.

  5. Pineapple! by Evil+W1zard · · Score: 5, Funny

    Time to go buy some stock in Dole!

    Oh I can see it now... Healthy, Tasty Pineapple Flavored Cigarettes that have no Surgeon General's Warning.

    --
    News Reporters Make Tasty Polar Bear Treats!
    1. Re:Pineapple! by Ingolfke · · Score: 1

      Time to go buy some stock in Dole!

      Bob Dole?

    2. Re:Pineapple! by Scaba · · Score: 1

      On a side note, Steve Case, beloved founder of AOL, is a majority shareholder in America's largest producer of pineapples.

    3. Re:Pineapple! by mrchaotica · · Score: 2, Insightful

      Nah, even if you eliminated the cancer, cigarettes still have a whole bunch of other bad side effects.

      --

      "[Regarding the 'cloud,'] ownership was what made America different than Russia." -- Woz

    4. Re:Pineapple! by Tiger4 · · Score: 1

      I for one Welcome our new Pineapple saviours! I look forward to helping them stamp out the insidious Cantelope-Honeydew melon buffet tray cabal.

      --
      Behold, this dreamer cometh. Come now, and let us slay him... and we shall see what will become of his dreams.
    5. Re:Pineapple! by line.at.infinity · · Score: 1

      Even if cigarettes didn't give you cancer, it can still give you emphysema, heart attack, miscarriage, more wrinkles, bad odor, addiction, and eating disorder.

  6. Cures and money. by HillBilly · · Score: 5, Insightful

    Cures for a lot of diseases probably already exist but there is no money in curering people, just treating their symptoms. You really think drug companies care about your health?

    --
    "Go into the hall of mirrors and have a bloody hard look at yourself" - HG Nelson
    1. Re:Cures and money. by team99parody · · Score: 5, Funny
      "You really think drug companies care about your health?"

      Would it even be legal for them to do so if they wanted to?

      Wouldn't that violate their fiduciary responsibilities to their shareholders? It'd be like microsoft killing off their upgrade revenue by releasing a secure OS.

    2. Re:Cures and money. by Virak · · Score: 1

      I seriously doubt that every single drug company has a cure for cancer and is just holding it back. They may be powerful, but they're not that powerful.

    3. Re:Cures and money. by Rei · · Score: 5, Insightful

      If you survive longer, you rack up more medical bills. Curing HIV might not be a big money-maker, but do you know how many drugs senior citizens take? Keeping them alive to continue their medications would be a gold mine.

      --
      "It felt almost as good as stealing cars from grandma." -- Margaret Thatcher, probably.
    4. Re:Cures and money. by Anonymous Coward · · Score: 3, Insightful

      Right. Because none of the researchers for those drug companies have family members, friends or acquiantances that might be ill -- they're all in it for the money, even if it kills their parents.

    5. Re:Cures and money. by DownTownMT · · Score: 3, Interesting
      Cures for a lot of diseases probably already exist but there is no money in curering people, just treating their symptoms.

      As much as I wish that wasn't true I'm afraid it is. I'm dating an immunologist right now, and even she has told me that the pharmaceutical companies aren't interested in cures, only lifestyle drugs such as giving an 80 year old a woody, or helping people loose weight. Basically there's no profit in cures, only the drugs you have to keep taking.

      I just find it sickening that thousands die each year from HIV, cancer, and the sorts, but hey, old people are having sex!

      --
      "Insert Sig Here"
    6. Re:Cures and money. by TripMaster+Monkey · · Score: 4, Funny


      I was wondering when someone would work in the obligatory Slashdot M$ slam...well done!

      --
      ____

      ~ |rip/\/\aster /\/\onkey

    7. Re:Cures and money. by Ingolfke · · Score: 3, Funny

      If you survive longer, you rack up more medical bills. Curing HIV might not be a big money-maker, but do you know how many drugs senior citizens take? Keeping them alive to continue their medications would be a gold mine.

      Exactly... here's you cure for AIDS and your free trial sample of Viagra... go get em champ.

    8. Re:Cures and money. by Iriel · · Score: 1

      You're absolutely right in most respects; after all, americans can now afford a lexus with greater ease than their daily medication. However, there are a lot of people that cry conspiracy (I'm not claiming that you're one of them) that government X is keeping all the cures from people for the same statement you have made. Then again, with some of the bleeding edge and virtually restriction-free medical reasearch centers being built in places like Singapore and other countries than haven't been as tainted in the medical world, I find it hard to believe that not even 1 country out of almost 200 in the world has yet to distribute one of the many cures for AIDS that conspiracy buffs talk about.

      I think some have come further than others to treating it and there is even one cure for AIDS that I can think of off the top of my head, but it also has a 50% mortality rate. I think that may be another large chunk of the 'cures' out there: things still far from properly tested or safe.

      --
      Perfecting Discordia
      www.stevenvansickle.com
    9. Re:Cures and money. by mbrewthx · · Score: 1

      And that's why the scientists created Robots..
      To steal old people's medicine, so they would have to replace them using out of pocket money and purchase robot insurance from Old Glory.

      --
      __________ Leave me alone I'm compiling a RPG II program on my S/36...Thanks to metamucil I'm a Regular Meta Moderator
    10. Re:Cures and money. by OrionoirO · · Score: 4, Insightful

      Cures for a lot of diseases probably already exist but there is no money in curering people, just treating their symptoms. You really think drug companies care about your health?

      While drug companies are probably most concerned with profit, there is quite a bit of money to be made in curing people. Imagine company A has a treatment, and company B has a cure. People will buy company B's cure.

      Also, the HIV drug described in TFA, even if it worked perfectly, would probably require someone who was infected to use it for the rest of their lives to prevent cells that were already infected with the virus from becoming active and spreading it. This would make anyone who produced the drug quite a bit of money.
    11. Re:Cures and money. by eric_brissette · · Score: 1

      Well, the picture in the first article gives a clue to the drug company's solution to that problem: They get to charge you for treating GHS (ginormous hand syndrome) which is apparently is a side effect of ingesting pineapple extract.

    12. Re:Cures and money. by badmammajamma · · Score: 1

      Possibly, but then it's not a cure -- it's a treatment.

      --
      Any man who afflicts the human race with ideas must be prepared to see them misunderstood. -- H. L. Mencken
    13. Re:Cures and money. by Anonymous Coward · · Score: 2, Insightful

      I don't think the cures "exist", it's just that the economic forces, the invisible hands, guide them toward looking for treatments rather than cures. It's just the nature of the business. They don't conciously go to work in the morning thinking "I better not find a cheap cure for cancer today".

      Kinda sad really. There is NO solution to this problem other than "try to stay healthy".. I.e. there is no incentive structure that would maximize the cures on the market.

      However reducing the strength of medical patents might be a way to allow smaller, more "morally guided" companies to get in the game. I dunno.

    14. Re:Cures and money. by Necromancyr · · Score: 4, Insightful

      Well, you'd better tell your immunologist friend to go work at a few of the companies, talk to some of the project managers, or hell - attend the BIO http://www.bio.com/ conference.

      It's disconcerting to me that an immunologist doesn't realize that treating symptoms are easy, and a HELL of a lot easier to get past the FDA, then something that causes issues in a persons system but cures them.

      Seriously, it's the biggest problem right now that has companies redefining what to make. People can't deal with a 1 in 20,000 chance they may have a higher chance of a heart attack if they take drug X, even though without drug X they are in constant pain every day all day.

      The american public refuses to accept any danger/risk at all from there medications - and because of this it takes a HELL of a lot longer to develop anything then it did before.

      The first vaccines available got people sick left and right - but people took them anyway, even with the 1 in 10000 or 1 in 1000 risk because once you actually got the disease, you had a MUCH lower chance of surviving.

      Moral of the story? Get educated before you make comments - even if someone who's an 'expert' tells you something.

    15. Re:Cures and money. by JhohannaVH · · Score: 1

      But the problem with the old people having sex is that they are becoming the fastest growing population with the HIV Virus. *boo*

      So what can we do about it all? I would like to see a law enacted that would prevent the phama companies from holding back 'cures' and vaccines. I really would. But ... they are lining our politicians pockets, so we get to be screwed.
      Note: Health Insurance companies do not cover 'lifestyle drugs' - Aetna and Cigna do not. I had to prove that I have a disability to get a stinkin' bottle of Vioxx. Boy do I regret that now. :P But, Medicare and Medical do! WTF? Sex offending welfare recipients can get viagra, but um, hello... I can't get the drugs I need to allow me to breathe or move? We seriously need to hold the companies responsible.

      And to that end... I have already started boycotting Bayer for selling tainted blood overseas and contributing to the death of thousands.

      Jho

      --
      Sorry man... the Internet pooped on me.
    16. Re:Cures and money. by Anonymous Coward · · Score: 0

      You might also find it even more frustrating when you consider that most of the basic drug research is not paid for by the drug companies but by taxpayers in many countries. Here in the U.S. two of the most commerically viable drugs of the last few decades (AZT and Viagra) were developed by researchers at the National Institutes of Health. They were then sold to a private company (Merc and Pfeizer I believe) who now demand protection for "their" intellectual property fom the U.S. Government even as they charge a premium for these drugs.

      BTW Viagra was discovered as a side-effect of heart research. Ther focus was on drugs that would dialate blood vessels.

    17. Re:Cures and money. by Anonymous Coward · · Score: 0

      And yet so true.

      Libertarians are mostly silent on the issue when people ask whether without government oversight if the companies will actually work to the benefit of humans. Those that aren't generally look down, shuffle their feet, then mumble "well, in a truly free and informed marketplace, people will vote with their walLOOK! A FLYING $100 BILL!" and then run away.

    18. Re:Cures and money. by sesshomaru · · Score: 1
      --
      "MIT betrayed all of its basic principles."
    19. Re:Cures and money. by neal3350 · · Score: 1
      Although there is almost no money in the US health system for curing people, many other countries have state supported healthcare. They actually have a financial incentive to produce cures or at least pay for research to that effect.

      Even though a lot of research goes on in the US, at least other countries can continue providing us with cures while US companies are "looking out for their stockholders".

    20. Re:Cures and money. by Anonymous Coward · · Score: 0

      Drug companies don't care about your health, but the HMOs have a lot of money and influence as well, and they sure as hell don't want to pay for interminable healthcare. A doctor once told me that if you have kidney disease then your insurance will do everything they can to help you get a new kidney, because they don't want to have to pay for dialysis. If you have liver failure, they won't help much, because you're just going to die for free.

      Plus, can you imagine the class-action suit if somebody found out a drug company was witholding a cure for a major disease? We're talking Billions.

      So what I'm saying is that the greedy nature of lawyers and companies can counteract the greedy nature of other companies.

    21. Re:Cures and money. by Rei · · Score: 4, Insightful

      Yeah. Because shareholders in drug companies vote their shares in a manner designed to help the employees families, as opposed to in a manner designed to maximize their profits. And because shareholders hand onto shares of stock of drug companies that aren't profitable because they're working for common benefit as opposed to profit (instead of dumping those shares and buying up shares of a profitable drug company).

      Sometimes, the interests of "profit" and "common good" overlap. But when they don't, in a market economy, who do you think wins?

      --
      "It felt almost as good as stealing cars from grandma." -- Margaret Thatcher, probably.
    22. Re:Cures and money. by Anonymous Coward · · Score: 1, Interesting

      Funnily, the current treatments for cancer are about as profitable as it gets for drug companies. If the treatments were any better people would go into remission sooner, (needing less drugs) and if they were any worse people would die quicker (needing less drugs).

    23. Re:Cures and money. by Neoprofin · · Score: 0

      It's just like Johnny Nemonic!

    24. Re:Cures and money. by Jaysyn · · Score: 1

      If that is ever discovered to be true, I see a *lot* of lynchings in the future. But seeing as CEO's die of cancer too, I kinda doubt it.

      Jaysyn

      --
      There is a war going on for your mind.
    25. Re:Cures and money. by advocate_one · · Score: 1
      even with the 1 in 10000 or 1 in 1000 risk because once you actually got the disease, you had a MUCH lower chance of surviving.

      From what I hear, the vaccine for Bird Flu has a 1% fatality rate... tough odds when the disease itself has an 80% fatality rate...

      --
      Donald 'Duck' Dunn: We had a band powerful enough to turn goat piss into gasoline.
    26. Re:Cures and money. by porcupine8 · · Score: 2, Insightful
      This was the whole issue with the recent case of the little girl whose parents refused to give her radiation therapy and her cancer came back... The radiation treatment doubles your chance of getting leukemia (though the chance is still like less than 1%), slightly raises your odds of breast cancer when you're 50+, and can cause heart damage equal to having one other risk factor (such as family history or high cholesterol).

      However, without radiation, the odds of the cancer coming back are 25-40%. (Well, in certain cases - I don't know all the details of her stage etc, but I had the same cancer as her so I know some generalizations.) But since she was "just fine," her parents refused to take the risks above and instead took the much worse risk, and lost. The risk of recurrence should have been scarier, but people feel better about the risk of doing nothing than the risk of taking a treatment.

      --
      Warning: Apple/Nintendo fangirl. Likes her electronics cute & cuddly. May be rabid.
    27. Re:Cures and money. by LurkerXXX · · Score: 3, Interesting
      Another tinfoil hat conspiracy guy eh? Here's some news for you. Much/most of the biology research done in the U.S. is paid for by the National Institutes of Health. That's the government, not drug companies. To the tune of $28 billion or so last year alone. That's your tax dollars at work.

      Most done by labs at Universities like mine. If I find a cure for a disease, I'd get famous in my field. Not only that, but it would pretty much ensure that I will have all the future funding for my research that I could want.

      Even besides all that, there are plenty of folks in my lab, in my department, and collegues at other Universities I collaborate with who know what I'm working on and how things are going. Hiding something major like a cure for a major disease just isn't going to happen. There is zero in it for me to hide my research, even if it were possible.

      Now the drug companies would be the ones to actually produce the drug for sale. They might charge you an arm and a leg for the pill, but it wouldn't be hidden from you.

      That is all. We now return you to your regular worries about the aliens reading your brainwaves. And look out for the black helicoptors!

    28. Re:Cures and money. by Atzanteol · · Score: 1

      And how many cures for Aids, the common cold, and cancer have these countries provided so far?

      --
      "Ignorance more frequently begets confidence than does knowledge"

      - Charles Darwin
    29. Re:Cures and money. by Anonymous Coward · · Score: 0

      Have you been skipping on your paranoia pills again?? You know you can't post on Slashdot without OD'ing on paranoia first... Get with it!

    30. Re:Cures and money. by DavidTC · · Score: 1

      You missed the point. A researcher would talk.

      --
      If corporations are people, aren't stockholders guilty of slavery?
    31. Re:Cures and money. by timster · · Score: 2, Insightful

      I've never seen any evidence that shareholders vote in their own interest or in any logical fashion at all. Rather, it seems to be the norm to let the executive team run the company. Shareholders often vote with their feet, but this doesn't directly control a company's decisions, especially since the shareholders who hold (or buy) are likely to be those that have faith in the executive team.

      So individual choices might have more of an effect than you think. I remember an interview with an industry exec where he explained that his children (I think) had cystic fibrosis, and that gave him perspective that inspired him to push for new and better drugs.

      I'm sure that it's marketing when an exec speaks like that, but that doesn't mean it's completely false. There are a lot of drug companies still, and it's reasonable to expect that some of them act purely in self-interest while others take a broader view. There are many successful companies in many industries where building a better world is part of the corporate strategy.

      Perhaps I am merely being optimistic because I live essentially at the mercy of Wyeth-Ayerst and Fujisawa, but there you go.

      --
      I have seen the future, and it is inconvenient.
    32. Re:Cures and money. by jejones · · Score: 1

      Been watching those late night infomercials?

      If there were actual cures, governments and companies facing insane medical expenses would pay a lot for them; it would be a bargain compared with the current ongoing perpetual money drain.

    33. Re:Cures and money. by jejones · · Score: 2, Interesting

      The american public refuses to accept any danger/risk at all from there medications - and because of this it takes a HELL of a lot longer to develop anything then it did before.

      Yup. Ironically, the litigious public provides an environment favoring quackery: for example, homeopathic "medicines," since they're all inert ingredients, are sure not to cause side-effects that would induce a lawsuit. (Never mind that they don't do any good...)

    34. Re:Cures and money. by fain0v · · Score: 1

      What the hell are you talking about? PEOPLE work at drug companies, and they most certainly do care about curing people. Many of the people that work for drug companies have lost loved ones to cancer, heart disease, etc. That's the reason why many began careers in research.

      That being said researchers don't necessarily get to pick their projects. They spend quite a bit of time working on cures for wrinkles and impotence as well as cancer.

    35. Re:Cures and money. by TotalReflection · · Score: 1

      when 80 years old you become, be as critical about sex you will not.

    36. Re:Cures and money. by BewireNomali · · Score: 2, Interesting

      i think that's his point though. not so much the quality of medicines being produced, or the manner in which the pharmaceutical evolutionary process works, in as much as the choices of drugs that seemingly are being developed by drug companies.

      Your point about the FDA doesn't obviate the fact that pharmaceutical companies systematically seek to treat symptoms instead of developing promising long term therapies for successful eradication of conditions. What it means is that the system is fscked from the top/down.

      The other issue about pharmaceutical companies is their steadfast refusal to look into nutraceuticals because of intellectual property issues. I'd be interested in seeing how much pharm money these researchers get to look into bromelain components. Interestingly enough, indigenous cultures have raved about the anti-inflammatory properties of bromelain forever and it has already been historically used as a medicine. In fact, there are a number of discrete compounds which exhibit medicinal effects that, because of intellectual property issues, don't get the money behind them to get detailed analysis.

      This is a case of PRESERVING THE STATUS QUO (i.e. incremental revenue increases) at the expense of the future of our society. It's a preserving of an existing infrastructure at the expense of a whole new way of thinking about medicine.

      We're the most medicated in the world, but we consistently get beaten in life expectancy by places like Andorra and Okinawa, Japan... places where few medications are taken.

      IMO, that's what the GP was getting at.

      --
      un burrito me trampeó.
    37. Re:Cures and money. by flynt · · Score: 1

      You really think drug companies care about your health?

      Are you familar with how medical research is done in the United States and the world? Apparently not. Drug companies obviously hire bright and talented scientists from across the world to come up with new drugs and treatment methods. But have you ever thought of the logistics of trying to cover up a cure?

      First of all, if your claim about the drug companies not caring for your health is true, and I don't dispute it, let's just assume it's true, then why would they be searching for a cure only to hide it? Do you realize how expensive medical research is? You haven't even defined what you mean by the word "cure", which is a very deep and important topic in and of itself. "Cures" aren't mathematical equations that are worked out and verified, or consequences of some basic axiomatic system. There is so much variability in the human biological system, that even agreeing what "cure" means is tough. Is AIDS "cured" right now? It depends on who you talk to. Most doctors would agree it is treatable, and there is nowhere near the amount of interest in it as there was say 10 or 15 years ago.

      Back to cures.
      Let's just say that a cure is some magical pill that gets rid of some disease with no harmful side effects. That's about as good as anyone can hope for. Where was this cure developed? If at a drug company, surely they had to test this cure on humans to verify that it worked. Where are these people who had cancer, took a pill, and now have no symptoms? Where are their doctors? Are they part of the conspiracy to cover up this cure? Would patients not tell their friends and family that they took some magical pill and their woes ceased? Most clinical trials (which is how drugs are proven effective) involve thousands of patients from several centers around the world. These centers are typically at well regarded universities or other famous hospitals. Do you think all these people are involved too, and simply keeping quiet about their cures? The point is, proving a drug successful or not depends on literally thousands of people from varied walks of live, almost all of which have no economic incentive to keep quiet.

      I want to also say that research as advanced as drug discovery is hardly done in isolation. It is unlikely that some private drug company has a secret lab filled with scientists who are not only so smart as to have discovered something completely different outside the research done at the world's best universities, but sinister enough to remain working at a company that would hide it. If scientist A's lab had a cure for cancer and was told to keep quiet, do you think he'd listen to his corporate overlords, or simply quit and receive accolades and awards, along with bringing down the evil drug company in the process? The point here is, the CEOS, who I admit are probably very interested in profit, aren't the ones designing cures and deeming them effective or not. It is a large team of scientists whose main interests are all probably not raising share prices, but distinction in their field. Is this too naive? Probably, but many scientists are in their fields for reasons of hopefully distinguishing themselves, so I can't imagine an entire team covering up something as important as a cure for a disease.

      So I'm not saying everyone involved in drug research is in it for the good of humanity, obviously not. But to find a cure for any diease, no matter how mundane, takes millions of dollars and thousands of managers, scientists, doctors, volunteers, patients, and auditors that it's too hard to swallow that there's some secret lab producing cures, testing them on humans, and then remaining quiet about it.

    38. Re:Cures and money. by flynt · · Score: 1

      Do shareholders actually get to vote on whether or not to release a drug proven effective at curing a disease to market?!

    39. Re:Cures and money. by sxmjmae · · Score: 1

      That is nice... those greedy companies will go bankrupt in the end.

      If some little start up company found the cure for cancer or HIV they would make a vast sum of money and the big pharmaceutical would lose a huge source of revenue and most likely go into bankruptcy. They invest heavily in these treatment drugs and need to sell them for years to ever see a return on their investments.

      If they had a known cure and with held it to make more money on treatments they could be charged with all sorts of crimes and sue buy surviving victims and beneficiaries of their corporate greed.

      That is why we need to donate money to research specific drugs. Or worse yet have line on your income tax form to donate money to government run research houses that are really trying to find a cure. Sadly we sometimes need the government to do what the public sector can not even it they do it really inefficient. For example in Canada we have Crown (or government) own business to do thing that are required for society to function. It cost more to do than it can bring in (For example public transit).

      --
      My Sig indicates the end of the comment I posted.
    40. Re:Cures and money. by Anonymous Coward · · Score: 0
      Sometimes, the interests of "profit" and "common good" overlap. But when they don't, in a market economy, who do you think wins?
      That's what government is for.
    41. Re:Cures and money. by jimicus · · Score: 1

      ICBW, but IIRC there's a list of "Vital Medications" held by the World Health organisation which have to be made available at a reasonable cost throughout the world under international law.

      Given the AIDS epidemic in Africa, a cure would get on that list so fast.... bye bye charging £500/dose.

    42. Re:Cures and money. by Rei · · Score: 1

      A balanced assessment. As someone who has a disease named after you, I'm sure you have a lot of input on the subject. :) As for myself, who has also taken a fairly wide variety of prescription drugs over the course of the years (for completely different reasons), I've had to rely on the "we developed this for Gigantic Market A, but it just happens to help you out as well" side of things.

      Anyways, back to the topic at hand. True, companies do widely varying amounts of "charity" work. It can even win them some shareholders, such as "social choice" mutual funds. But to date, I can only think of one single American drug company that hasn't focused the overwhelming majority of its efforts on what will make them money (and that company, OneWorld Health, only has one product currently). Look at how much money goes into treating sexual dysfunction, social disorders, and allergies. Compare that to how much goes into treating Leishmaniasis, Chagas, etc. Is this social responsibility? There's no denying that drug companies take part in charity cases (to varying degrees), but the bulk of their efforts are, as one would expect, focused on profit. Drug stocks are very profitable.

      --
      "It felt almost as good as stealing cars from grandma." -- Margaret Thatcher, probably.
    43. Re:Cures and money. by PsiPsiStar · · Score: 1

      Quite a few homeopathic medicines have been proven to be helpful based on lab studies.

      Check out tumeric (or it's derivative coumarin) on pubmed. Quercetin (found in apples and garlic).
      Garlic itself, for that matter. And a host of other organic compounds. These ingredients are active and helpful, though not often as powerful as the stuff you get behind the counter.

      --

      ___
      It's the end of my comment as I know it and I feel fine.
    44. Re:Cures and money. by kalayq · · Score: 1
      "The American public refuses to accept any danger/risk at all from there medications"

      Every once and a while I get to watch the American feed of some tv channels (I live in Canada), and a lot of the commercials I see are for pharmasutical products. At the end of each commercial, there is an announcer reading off a long list of side effects. After reading about this and speaking to a few American MD's, I have found out that people basically watch these commercials and then go to their doctors asking for the advertised drugs directly, and usually get them. The side effects are stated very clearly in these commercials, but it is these advertised drugs that are selling very well. Just something to think about.

    45. Re:Cures and money. by jonabbey · · Score: 1

      +1 on this. I'm an insulin dependent diabetic, and the med companies make serious bank on me.

      So much so that the nice companies sent representatives to meet and talk with me and to show off their products when I was in the intensive care ward getting my newly diagnosed diabetes under control, back in the day.

      I really do have to wonder what company would ever produce a continuous blood glucose measurement system that would kill off their test strip revenue, for instance, or the drug company that would spend a dime to cut off their insulin sales.

      Hopefully the insurance companies will act in their interest and help fund the development of such treatments, if they ever get to the point of proving themselves.

    46. Re:Cures and money. by Anonymous Coward · · Score: 0

      I'll take issue with your assertion that the american public wants this.

      I don't think they're given a choice any more. The FDA and AMA have become rather self-serving, and aren't directly accountable for their decisions.

      The average american, if you look at the boom in things like alternative therapies, will try the craziest things you would believe, and then some. Because of the legislated benefits to rent-seeking professions and corporations, the average american isn't even entitled to make their own medical decisions beyond a narrow selection made available by the establishment supposed to serve them.

    47. Re:Cures and money. by arodland · · Score: 1

      "You want us to sell you this stuff for $1/dose? You do realize that it costs us $200 a dose to produce, right? You do? Oh, well, it turns out... we don't actually have any. Management said some stuff about a whole lot of numbers and now we don't make that stuff."

    48. Re:Cures and money. by Anonymous Coward · · Score: 0

      do you know what homeopathic medicine is? my god..

    49. Re:Cures and money. by blitz487 · · Score: 1
      Since it costs nearly half a billion dollars to get a drug approved by the FDA, that naturally is going to discourage any but blockbuster drugs from ever being developed.

      Before the 1962 FDA amendments, drug development companies brought a much greater number and variety of new drugs to patients.

    50. Re:Cures and money. by dasunt · · Score: 2, Interesting
      Yup. Ironically, the litigious public provides an environment favoring quackery: for example, homeopathic "medicines," since they're all inert ingredients, are sure not to cause side-effects that would induce a lawsuit. (Never mind that they don't do any good...)

      I think you are mistaken. Quack medicine has had a long and successful history in the US. Homeopathy is nothing new.

      Unfortunately, much of the population is missing critical thinking skills. Part of this may be due to evolution: We evolved in small tribes, thus we may give anecdotal evidence more credit than its worth. Part of this is probably due to the fact that medicine tends to be rather advanced technology and requires knowledge to understand and evaluate.

      As a footnote, homeopathy may not be quack medicine. It may be possible that there is more than a placebo effect at work, and that water does "remember" what was contained in it, and that the memory of the non-diluted compound has a healing effect. This is judged extremely unlikely by most people (including myself) because it requires several possibilities that are almost certainly non-tree.

      This brings up another issue: Modern medicine, like many fields, tends to be based upon the probability that something is true or not true. There are uncertainties at the core of medicine. We don't know how some things work and why some people get better. We tend to use research and scientific models and check if the clinical evidence supports them. Small shifts in thought happen in medince all the time: mouth germs can cause heart disease, ulcers can be caused by bacteria. In all probability, there are mainstream medical treatments being prescriped today that are either not effective or harmful to the patient (proportionally, such treatments are probably not very common). In all probability, there are probably more effective treatments out there as well. If you are ignorant of scientific method, research studies, and statistics, its rather easy to start to believe that homeopathy is effective, especially when the homeopath explains what he does in psuedoscientific jargon.

      In the course of writing this comment, I found a slightly off-topic link discussing the 'myth' of the medical establishment fighting against the idea that bacteria causes stomach ulcers. The idea of a lone research fighting against the establishment makes a good story and for those unfamiliar with research, it may seem true, which is probably why such stories enter the pool of common knowledge. Unfortunately, with little else to go on, 'common knowledge' often leads to the wrong conclusion.

    51. Re:Cures and money. by eyeye · · Score: 1

      Your conspiracy theory is misplaced, the real conspiracy is that drug companies lobby to ban and restrict natural drugs (like pineapple extract perhaps) so they can sell their inferior side-effect inducing products instead.

      --
      Bush and Blair ate my sig!
    52. Re:Cures and money. by Anonymous Coward · · Score: 0

      first - a conspiracy to cover up a cure for cancer, AIDS, or HIV would take the cooperation of literally thousands of people. thousands.

      second - i may be naive, but i think that being able to put something like "2007-2009 - Discovered Cure For Cancer - Ended Plague of Millenium" on ones resume would far outweigh any sort of monetary gain from covering up such a cure. but that's just me.

    53. Re:Cures and money. by Fizzl · · Score: 1
      curering

      If that's a word in English language, I say that you have come a loooooong way from the times I started learning it. I always found English to be easy to learn because of absence of irregularly declinable verbs.
      .
      ..
      ...

      (I'm just putting words together. Nevermind me.)
    54. Re:Cures and money. by Strontium-90 · · Score: 1

      I really wish that I could mod you up a couple more points. I completely agree with what you said.

    55. Re:Cures and money. by lavaface · · Score: 1
      Much/most of the biology research done in the U.S. is paid for by the National Institutes of Health. That's the government, not drug companies. To the tune of $28 billion or so last year alone. That's your tax dollars at work . . .
      Now the drug companies would be the ones to actually produce the drug for sale. They might charge you an arm and a leg for the pill, but it wouldn't be hidden from you.

      This is something that irks me a bit. Our tax dollars provide a significant portion of medical research and when some drug seems lucrative, the pharmaceutical conglomerates spend money on extended trials and make insane profits off of it. It seems like our society would ultimately come out ahead if public institutions like universities and national research centers just went all the way and licensed their discoveries as non-patentable, public domain treatments. But I suppose that would be a bit too commmunistic for my fellow citizens' tastes.

    56. Re:Cures and money. by jimicus · · Score: 1

      Bit hard to maintain that argument if you're selling it on the open market in the developed world.

    57. Re:Cures and money. by rzbx · · Score: 1

      Actually, think about it this way. Cancer is something normal. Healthy people will clean cancer away throughout their lives. On the other hand, if a person is not healthy and/or there is something that is preventing the body from removing the cancer, it will simply grow.

      The drugs that companies make are really just some sort of molecule, chemical, etc. that is known to attack a specific type of cancer. We find cancer killing chemicals in everything, such as fruit, plants, or even animals. This is not the important part really, they are all just specific substances that cancer just doesn't like in some way.

      The problem is, isolating these various chemicals and injecting them into the body has other consequences. Just look at all the drugs that have warnings about causing liver problems. The liver, I'm sure you know, cleans our system. Bombarding the body with a certain chemical can kill off a cancer, but why do it with such a blunt tool? Like killing a fly with a hammer, you just might put a hole in your wall.

      Compare the health of the average American with those of other countries (U.S. is leading in terms of specific health problems). Cancer is nothing new, but in the past few decades it has become worse. Why? Chemicals in industrial use, processed foods, additives, stress, chemicals absorbed by the plants and animals we eat, electromagnetic radiation, etc. Now although any one of these may be small in terms of toxicity to our bodies, a combination of them and an unhealthy state of body and mind will do the trick.

      Once the person is a little unhealthy, they are more easily harmed by other chemicals and organisms. A huge part of the population is very sick and does not even realize it. People working within a drug company may or may not what is going on. One can be a science genius, but then becomes science vs natural growth of a living cancer cell. Like an arms race between the tools of science and the complicated human body and the cancer that can grow within it.

      Drug companies really have no interest in curing people (although people in the institution actually do). There is little money in doing so and there are many cancer causing substances. It is not that there is a conspiracy (although on some levels there are, the truth is hard to swallow, sorry). Some really want to cure disease etc. but they go about it the wrong way. Why fight cancer when you could prevent it from occuring in the first place? Why fight cancer using blunt tools when you can bring a person back to health and let the body take care of it?

      It is mostly ignorance. It has nothing to do with some big drug company conspiracy, some more or less know the truth (which in some cases does make it a conspiracy), others are just aren't aware of the truth.

      Also,
      "We now return you to your regular worries about the aliens reading your brainwaves. And look out for the black helicoptors!"

      is not a comment that shines light onto the argument at hand. Truth is stronger than attempting to make someone look like a nut-case.

      Btw, I am not saying there is no purpose in researching medicine and making drugs. But when money became the driving force behind medicine, hell broke loose.

      --
      Question everything.
    58. Re:Cures and money. by bondjamesbond · · Score: 1

      Fiduciary responsibilities??? The pharmacutical companies have the US govt in their pockets. They are exempt from any responsibilities. And shareholders don't give a shit as long as they get their money. So, the bottom line is that (as the parent said) they don't want to cure. They want to TREAT you for the rest of your life.

    59. Re:Cures and money. by DrZZ · · Score: 1

      You obviously have no experience with university tech transfer offices. They are ten times more greedy than the companies. Although some amount of reality has been creeping into the system, universities (at least in the US) are notorious for thinking that their dicoveries are worth tons of money. Oh and you are also clueless if you think that university research delivers ready to go drugs to pharm companies. University research is vital for the the overall effort, but in terms of getting a drug on the market, most of the time it gets you 1-2% of the way there. Just like the stories here. They are no more than 1-2% of the way to being a useful drug and to claim that whoever invests 99% of the resources should get nothing doesn't sound reasonable.

    60. Re:Cures and money. by twiddlingbits · · Score: 1

      Your numbers are full of crap and misleading to boot. Biology research is NOT the same as DRUG reasearch. Biology research covers everything from the migratory patterns of Caribou to studies on aging. As an example about your dollar figures, I went and looked up a major drug company financials from 2004 and then alone spent $7.7B on R&D and this company is not even the biggest drug company.

      I don't think drug companies are hiding anything either, and researchers even less. With the publish or perish plan for tenure in plan for most Universities they are eager to get the news out if something good is found. The drug companies are a bit slower as they tend to need to protect the IP and Patent the drugs which takes time, and THEN they need FDA approval which takes more time. IF the drug in the referenced article is indeed the "cure" for AIDS/Cancer then it will likely still be 2 or more years before you can buy it in the USA.

    61. Re:Cures and money. by LurkerXXX · · Score: 2, Informative
      Sorry, my numbers are not crap.

      If you want to study migratory patterns of Caribou or the depletion of the salmon population, you apply for a grant from the Department of Agriculture, or the Fish and Wildlife Service, or the Department of Commerce. You don't go to the NIH.

      There are lots and lots of funding agencies that do 'biology' research other than the NIH. I've been on grants studying radiation biology from the Department of Energy. I've been supported by grants from rotory clubs. All of that has nothing to do with the $28 Billion last year that the NIH alone spent.

      Apparently you don't know what the NIH is. The National Institutes of Health are:

      • National Cancer Institute (NCI)
      • National Eye Institute (NEI)
      • National Heart, Lung, and Blood Institute (NHLBI)
      • National Human Genome Research Institute (NHGRI)
      • National Institute on Aging (NIA)
      • National Institute on Alcohol Abuse and Alcoholism (NIAAA)
      • National Institute of Allergy and Infectious Diseases (NIAID)
      • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
      • National Institute of Biomedical Imaging and Bioengineering (NIBIB)
      • National Institute of Child Health and Human Development (NICHD)
      • National Institute on Deafness and Other Communication Disorders (NIDCD)
      • National Institute of Dental and Craniofacial Research (NIDCR)
      • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
      • National Institute on Drug Abuse (NIDA)
      • National Institute of Environmental Health Sciences (NIEHS)
      • National Institute of General Medical Sciences (NIGMS)
      • National Institute of Mental Health (NIMH)
      • National Institute of Neurological Disorders and Stroke (NINDS)
      • National Institute of Nursing Research (NINR)
      • National Library of Medicine (NLM)
      Gee, what do all those things have in common? They seem to be about basic biology and human HEALTH. None of them seem directly related to Caribou. Maybe because that's not where Caribou researchers typically get their research money, but someone studying cancer might.

      You pointed to a 'major' pharm company spending 7 billion. There aren't that many major players, and most of their R&D money are spent on drug trials. That's an expensive part of the research process, but it's the end stage. Most of that money isn't spent discovering a cure, but making sure the possible cure doesn't kill you in other ways. That's not drug discovery, that's human drug toxicity testing. The universities around the country are where most of the real research happens.

    62. Re:Cures and money. by LurkerXXX · · Score: 1
      Aside from what the other poster said about tech-transfer (most of which is true), the biology research in the university labs usually stops at the point of a likely cure that works in animal model systems.

      At that point is where all the patent stuff happens and the pharm companies take over. There is still more to do. The human drug trials. There are usually 3 stages to those trials and they are extremely costly to do. You have a large number of patients (if you get to the stage 3 trials) which must each see a doctor ($$$) probably a nurse or two ($$) and usually get some type of blood tests, etc, run ($$$). Those drug trials usually take months to years to complete, requiring multiple trips to the physician/nurse/testing ($$$$$$$$$$$). Plus, since they are doing experimental stuff, the insurance for the doctors isn't going to be cheap, even compared to a normal practice ($$$$).

      Although most of the 'research' may be done by the research labs in universities, the pharm companies have a large investment in the clinical trials (which often don't work out). That's one of the reasons they try to recoup so much money with jacked up drug prices. Their other big expense is their fleet of drug reps who make weekly or bi-weekly circuits around to tell your local doctor about their new wonder drug. Check how many drug reps companies have out there (and what they are paid) and you will find where a HUGE amount of pharm money really goes.

    63. Re:Cures and money. by Anonymous Coward · · Score: 0

      Viagra???

      Are you nuts? If you help them die off a heart attack, there goes your revenue stream!

    64. Re:Cures and money. by forty7 · · Score: 1

      You pointed to a 'major' pharm company spending 7 billion. There aren't that many major players, and most of their R&D money are spent on drug trials. That's an expensive part of the research process, but it's the end stage. Most of that money isn't spent discovering a cure, but making sure the possible cure doesn't kill you in other ways. That's not drug discovery, that's human drug toxicity testing. The universities around the country are where most of the real research happens.

      Since I happen to know quite a bit about the drug company/clinical trial end of the business, I thought I'd speak up a bit here. It's true that a huge chunk of drug research is not funded by the drug companies themselves, but it would be wrong to imply that they don't do any research of their own past "human drug toxicity testing". For one thing, they do some genuine drug discovery of their own.

      It's true that much of their R&D budget is spent on clinical trials, but those are, at best, only half "toxicity testing". In order to get a drug approved by the FDA, you're required not only to prove its safety, but also its efficacy, through clinical trials. This is why companies often spend lots and lots of money on new trials for drugs that have already been approved for one indication: a drug must be separately tested and approved for each indication. There's usually also long-term safety trials that continue even after a drug has been approved. It's not uncommon for clinical trials to run three or four years before they're complete, and it would be some time after that before the formal approval application could be submitted.

      For those who are still interested, note that this doesn't mean that drugs have always been tested for efficacy on everything they're used to treat -- once a drug has been approved for one thing, it can legally be prescribed for anything else at the physician's discretion (off-label prescription). The company is not permitted to make any claims about using it for that purpose, though, even things like 'may be used to treat X'. These claims, and drug packaging and labeling in general, are very highly regulated.

    65. Re:Cures and money. by Dwonis · · Score: 1
      Would it even be legal for them to do so if they wanted to? Wouldn't that violate their fiduciary responsibilities to their shareholders? It'd be like microsoft killing off their upgrade revenue by releasing a secure OS.

      Yeah... I can see that shareholder lawsuit going somewhere...

    66. Re:Cures and money. by LurkerXXX · · Score: 1

      Sorry, I didn't mean to imply that they didn't do any real research at all. I've been to some very good talks by researachers from pharm companies. The 'most' was supposed to qualify it that they do do some, but that's not where the largest chunk of their money is usually directed. Drug trials are the huge expense. Lots of money is involved there. They are a 'profit center' for the hospitals that do them.

    67. Re:Cures and money. by twiddlingbits · · Score: 1

      The drug companies fund most of the research ( not all of that is in house..a lot goes to Universities). The cost is staggering to get a drug to market. I'm not sure Asprin would make it past the FDA reviews today. I know what the NIH is and what it does. The figures are still misleading. The "Biology" dollars are spread across research and studies in the many different areas you indicated not just Cancer and HIV which is what the article addresses (which combined probably get 60% of the funds). Biology research and research for developing Drugs (BioChemistry) are definitely NOT the same thing. There is certainly some cross-over especially in the areas of drugs from natural sources such as Tamoxifen. The NIH pays for a lot of things, drug testing of Company X new drugs is not usually one of them. There is a lot of money spent understanding diseases, transmission mechamisms, and a lot of reporting on disease fatalites (and the crazy bogus AIDS data) comes out of the NIH budget. Top Drug companies, Pfizer, Merck, Abbot, McKesson, Bristol-Meyers, Wyeth, Am. Pharm, J&J, Celgene, Lilly, Bayer, Aventis..the list goes on. What was that about there not being but a few. I can find 50 easy on Google. The money they spend verus what the NIH spends make the NIH money look like peanuts.

    68. Re:Cures and money. by TheoMurpse · · Score: 1

      If I was a shareholder in a company that developed a cure for the HIV virus, I'd sure as hell tell someone. News would leak. You can't keep something like that a secret. Not only that, but there are scientists who find the cure -- not only would they want recognition, but they would want to help people, so, even if they were under a NDA, I would expect a scientist to leak.
      Hell, if Mr. X found a cure for HIV while working for Pfizer and Pfizer didn't want to disclose, and Mr. X announced We now have a cure and was sued for breach of NDA, I think there would be some heavy duty work by the various governments of the world to bring the virus to the public (think anti-trust suits). If not that, perhaps the government would buy the whole company.
      Following the law has never stopped governments before -- who in the entire world would want to stand up and accept the blame for stopping the cure for AIDS.

      Besides, you seem to ignore the fact that
      1)Scientists who discover the cure are people with friends and family,
      2)Stockholders in the company with the cure are people with friends and family, and
      3)Executives at the helm of the company with the cure are people with friends and family (believe it or not)

      Do you think every single one of these people involved would keep the cure secret from the public? Once it became known to the public that the cure existed, there would be riots and political posturing by all to bring the cure to the people. I guarantee you any politician with "brought cure to AIDS to the masses" would get elected to any office they ran for.

      Or do you have that little faith in humanity that all stockholders, executives and scientists would sell out their friends and family and indeed all of humanity for the sake of Mean Green?

    69. Re:Cures and money. by flynt · · Score: 1

      You obviously did not research the side effects of taking large quantities of pineapple extract.

    70. Re:Cures and money. by Anonymous Coward · · Score: 0
      Quoth LurkerXXX:
      That is all. We now return you to your regular worries about the aliens reading your brainwaves. And look out for the black helicoptors!


      It's funny how brainwave reading aliens and black helicopters always seem to show up right next to each other. One falls under science fiction, but the other is one of the most frightening manifestations of military might.

      Imagine you're winding your way through a national forest near the mexican border, boggling at the sights, the smells, the sounds, all the rest of what goes along with being in paradise. Imagine that all of a sudden out of goddamned nowhere a black helicopter appears, hovering above you, spotlight on. What might be going through your mind? Would you be thinking, this can't be happening, black helicopters are what the tinfoil hat brigade believe in, someone must have slipped me some mind-ripping drugs? You'd more likely be considering the meaning of mortality.

      Black helicopters are very real and very scary. Don't think that anything you don't see every day can't possibly be.
    71. Re:Cures and money. by LurkerXXX · · Score: 1
      I know what the NIH is and what it does.

      Obviously not, or you wouldn't suggest they paid for studies of the migration patterns of Caribou.

      The "Biology" dollars are spread across research and studies in the many different areas you indicated not just Cancer and HIV which is what the article addresses (which combined probably get 60% of the funds).

      The pharm companies do research in many different areas, not just Cancer and HIV eithre. What's your point? No, the $28 billion from NIH isn't all spent on Cancer and Aids. Neither is the 7.7 billion spent by that nameless pharm company you mentioned in your other post.

      The NIH pays for a lot of things, drug testing of Company X new drugs is not usually one of them.

      The NIH doesn't pay for the clinical trials of Company X new drugs, but they very well may have paid for all the basic research determining what the biological basis for the disease was, what specific pathways were involved, what molecules were good targets to hit, found the correct drug that *IS* that new drug X, and done all the testing of that drug in tissue culture and as well as in an animal model system. At that point, yes, the drug companies spend the money to test the drug in actual people.

      There is a lot of money spent understanding diseases, transmission mechamisms, and a lot of reporting on disease fatalites (and the crazy bogus AIDS data) comes out of the NIH budget.

      How do you propose the drug companies magically make a new drug without understanding the basic disease and what pathways and molecules they should target. That *IS* the research that leads to the curing drugs. Remember, the drug companies have many other expenses in R&D, such as how to reduce the cost of each pill they make. That's for profits for the company, not for curing the disease. A large part of the R&D budgets for these companies (some analysts claim up to half, but I'm skeptical if it's that high) also go for "me-too" drugs. Slight modifications to the chemical structures of drugs other companies are making so that the new company can also have a drug to sell to treat the same problem. This isn't great new drug discovery.

      Drug companies, Pfizer, Merck, Abbot, McKesson, Bristol-Meyers, Wyeth, Am. Pharm, J&J, Celgene, Lilly, Bayer, Aventis..the list goes on. What was that about there not being but a few. I can find 50 easy on Google.

      I bow to your leet google skills.
      Now, let's look at the numbers... I'll copy your leet googling and try to find some R&D bugets for fairly recent years... A quick google for R&D bugets from a fairly recent year:

      • Wyeth 2.4 billion
      • Pfizer 3 billion
      • Merck 3 billion
      • Abbot 1.7 billion
      • Bristol-Myers 2 billion
      • J&J 3 billion
      • Eli Lilly 2.1 billion
      • ..
      • Bayer - A european based company
      • Aventis - A european based company

        Hold it: If you are going to toss in European based pharm companies, you are going to have to include the European government sponsored research budget along with that of the NIH. Hint, it's not an insignificant amount of money.

      • McKesson - This company is a pharmaceuticals distributor. NOT A MANUFACTURER. THEY HAVE NO DRUG DISCOVERY R&D BUDGET!!!! Your googling sucks.
      The money they spend verus what the NIH spends make the NIH money look like peanuts.

      Even the pharmaceutical lobby PhRMA (which includes the non-us based pharm companies) claims their total R&D budget is only about equal to that of the NIH. Now add in the goverment funded research for all those EU, etc, countries. The goverment funded research budget is larger than that of the pharm companies. It's not 'peanuts'.

    72. Re:Cures and money. by LurkerXXX · · Score: 1
      Imagine you're winding your way through a national forest near the mexican border, boggling at the sights, the smells, the sounds, all the rest of what goes along with being in paradise. Imagine that all of a sudden out of goddamned nowhere a black helicopter appears, hovering above you, spotlight on. What might be going through your mind?

      Border patrol looking for illegal immigrants.

    73. Re:Cures and money. by mattyrobinson69 · · Score: 1

      although technically feasable to cure the common cold:

      1: whats the point, its not all that bad compared to a lot of things which are curable/preventable(?) or could be treated better (asthma)
      2: its constantly changing, next year's strain is different to this years.

    74. Re:Cures and money. by tsotha · · Score: 1
      Look at how much money goes into treating sexual dysfunction, social disorders, and allergies. Compare that to how much goes into treating Leishmaniasis, Chagas, etc. Is this social responsibility? There's no denying that drug companies take part in charity cases (to varying degrees), but the bulk of their efforts are, as one would expect, focused on profit. Drug stocks are very profitable.

      But where would the money come from for those Leishmaniasis and Chagas treatments? You couldn't very well charge your customers the true cost - they can't even do that for AIDS drugs which have a much larger "customer" base. The way I see it, a new treatment for anything is progress, since it adds to the body of scientific knowledge. If the choice is between drug companies that turn out Viagra clones and no commercial drug development, I'll take the drug companies.

      Of course you could have government funding of drug research. France, for example, does a lot of that (and with some success). But that model doesn't seem to be as productive as the capitalist one for research in general.

      We've had some success here in the US with deals that go something like "if you're willing to do the research on this disease the taxpayers will pay for it and then allow you to keep the profit." That's not very popular with the voters, since they don't see why they should be charged twice, but at least you may end up with useful drugs.

      The Orphan Drug Act was an attempt to address the problem, but it's been much abused. I know if it's still in effect or not.

  7. Great, one more thing for Spam to pimp. by doublem · · Score: 5, Funny

    Herbal Pineapple extract Spam in 5... 4... 3...

    --
    "Live Free or Die." Don't like it? Then keep out of the USA
    1. Re:Great, one more thing for Spam to pimp. by Moses_Gunn · · Score: 1

      Mmmmm....pineapples and Spam...aagaghahghaghh...

    2. Re:Great, one more thing for Spam to pimp. by doublem · · Score: 1

      They make a great combo when grilled.

      --
      "Live Free or Die." Don't like it? Then keep out of the USA
  8. Pina Coladas by Bob+Cat+-+NYMPHS · · Score: 2, Funny

    I just KNEW they were good for me!

    1. Re:Pina Coladas by pHatidic · · Score: 1

      And getting caught in the rain?

    2. Re:Pina Coladas by Anonymous Coward · · Score: 0

      Nope, no cure for the cold yet...

    3. Re:Pina Coladas by Anonymous Coward · · Score: 0

      What kind of abstemious retard decided to mod this as 'overrated', Carrie Freakin' Nation?

  9. old news by Anonymous Coward · · Score: 5, Informative

    old news

    1: Planta Med. 1985 Dec;(6):538-9. Related Articles, Links Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus). Taussig SJ, Szekerczes J, Batkin S. PMID: 4095199 [PubMed - indexed for MEDLINE]
    1985.
    At least it's not a dupe.

    1. Re:old news by The_Mystic_For_Real · · Score: 4, Funny

      The news isn't the breakthrough, the news is that science is being done in Australia. No more 'Gator Studies' majors there anymore I guess.

      --

      _____

      Thank you.

    2. Re:old news by carlcub · · Score: 3, Informative

      Sure, in 1985, they knew that bromelaine would suppress tumor growth. I don't think they had identified the particular molecules that were responsible, though, which is what will lead to future viable treatments. It's not like you can inject pineapple extract into a living patient.

    3. Re:old news by Anonymous Coward · · Score: 1, Informative

      Knowing that bromelain inhibits tumour growth is old news.. but, identifying how/why is what this research group successfully accomplished.

      Knowing the proteins involved (ccz & ccs) will allow for scientists to create a variety of drugs (that target the same site with similar activity).

      As for the HIV news, it looks like it's mainly hype. Their clinical trial involved only 40 people. Most clinical trials usually involve hundreds to thousands, so it'll marketing of this drug won't be for a few more years.

    4. Re:old news by soft_guy · · Score: 1

      why not? pulp won't go through syringe?

      --
      Avoid Missing Ball for High Score
    5. Re:old news by Elwood+P+Dowd · · Score: 1
      It's not like you can inject pineapple extract into a living patient.
      GODDAMNIT!

      Why couldn't you have said that two hours ago?!
      --

      There are no trails. There are no trees out here.
    6. Re:old news by TonyMillion · · Score: 1

      You're a bit wrong there, Phase 1 clinical trials often only involve that many people, sometimes less.

      Phase 3 or OpenAccess trials are the type you're thinking about.

      For more information on HIV drugs, both released and in trial try this: http://www.aidsmeds.com/List.htm

    7. Re:old news by dbIII · · Score: 1
      science is being done in Australia. No more 'Gator Studies' majors there anymore I guess.
      Now that's just ignorant and offensive - there is no such thing as a gator studies major in Australia - the big lizards with teeth that live here are called crocodiles.

      On a more serious note, reasearch happens here, NASA outsourced their scramjet research to my home town in Australia nearly two decades ago, oddly enough at a time when the biggest industry in town was probably putting pineapples in tins.

  10. Hopefully... by rwven · · Score: 4, Insightful

    I just hope these don't fade into the background as a lot of these types of things do. i think the world is ready for some cures...

    1. Re:Hopefully... by Rosco+P.+Coltrane · · Score: 1

      i think the world is ready for some cures

      Please, I think the world had enough with one.

      --
      "A door is what a dog is perpetually on the wrong side of" - Ogden Nash
    2. Re:Hopefully... by Anonymous Coward · · Score: 0

      yes, yes - i totally agree with you. people often cure cancer and then say, "ah, fuck it. who cares about that?"

      what types of cures were you talking about? could it be that you're not a medical researcher, and you clearly don't have any regular contact with this type of stuff?

    3. Re:Hopefully... by Anonymous Coward · · Score: 0

      Could it be that you're a jackass with no memory? Could it be you missed the last 50 "oxygen cures cancer" stories? These things get posted on slashdot twice a week, and then someone at a lab somewhere quietly says "oops, we also had some bleach in there", and you never hear about it again. Obviously the hope was that this one would pan out.

    4. Re:Hopefully... by rwven · · Score: 1

      It was just a statement, not an attack on anything... Why do you and 90% of other /.'ers always assume people are trying to put down someone else....

  11. Awesome! by rockytriton · · Score: 0, Funny

    Now they should use "Fundable" to hold the cure hostage until they receive 1 MILLLLLLLION dollars! Or is that only for open source software?

  12. I dunno... by vykor · · Score: 4, Insightful

    Maybe I'm getting jaded these days, but it seems that every other week we have an announcement about a revolutionary breakthrough that's going to cure all these terminal conditions. And yet, we don't really seem to see masses of cancer patients getting cured outside these laboratory studies, in the way that antibiotics swept away most bacterial illnesses. Survival rates are up, sure, but most people are still dying and these conditions are still considered more or less terminal. Are the Powers That Be simply sitting on a bunch of cures, or do these things never turn out to be as promising as they were in experimental trials?

    1. Re:I dunno... by Anonymous Coward · · Score: 0

      It's called marketing. If your research is both published in academic journals and grabs headlines, you're that much more likely to receive tenure and funding.

    2. Re:I dunno... by FortKnox · · Score: 1

      Antibiotics were invented before the FDA and the 10 year process of testing medicine before making it available. That's why you hear about something and it fades away.

      --
      Good quote, too many chars. Seriously, the slashdot 120 char limit sucks!
    3. Re:I dunno... by deathcloset · · Score: 1

      That's a very good question.

      I remember this story on slashydot a while back that got me all excited telling my co-workers and anyone on the street that would listen.

      Of course, they will be starting human testing soon. so let's just hope the reason we don't see these treaments used on people sooner is simply a result of the beaurucratic slowdowns of groups like the USA's FDA.

      (of course, it's unwise to just start handing out treatments like they are popsicles without testing - but sometimes 5 years before approval seems a bit extreme).

    4. Re:I dunno... by Otter · · Score: 5, Insightful
      Are the Powers That Be simply sitting on a bunch of cures...

      Yeah, that's it. We're spending billions of dollars on research to find cures and not sell them. Then when patients die, we burglarize their homes during the funeral. Profit!

      Look. Killing certain human cells while not killing all the rest of the cells is hard. It's a lot harder than killing a foreign pathogen without killing the human, which is already a lot harder than, say, rebooting a server or modifying a Perl script.

      ...or do these things never turn out to be as promising as they were in experimental trials?

      Also, please note that the cancer treatment here hasn't been in human trials. (The AIDS treatment has.) It hasn't even been in animals yet. Will it fail to be as promising as the hyperventilating press release makes out? There's a 99.9999% chance that it will.

    5. Re:I dunno... by searstream · · Score: 1

      Survival rates are up, sure, but most people are still dying.

    6. Re:I dunno... by CornfedPig · · Score: 2, Informative

      The path from interesting research to safe, efficacious therapy is a long funnel with a verrrrrry narrow outlet. Many things that look interesting in vitro don't work in animal models (rats, dogs, etc.), much less people -- there's a lot more going on in a living body than in a petri dish, so even compounds that show promise early on can disappoint later. I was a venture investor in biotechnology companies for nearly nine years; one of our most promising portfolio companies had a drug candidate blow up in Phase III clinical trials (pretty damn close to the end of the funnel) because, despite all of the promising results in earlier stages of development, the drug simply didn't work in a statistically meaningful way in double-blind clinical trials. The FDA process can slow things down, to be sure, but the fundamental problem is that the biology of living creatures is extraordinarly complex and only imperfectly understood. No conspiracies needed -- this stuff is just very, very hard.

      --
      "It's not a bear, it's a hamster. A really, really large hamster."
    7. Re:I dunno... by da55id · · Score: 1

      This is EXACTLY why the Mprize (Methuselah Mouse Prize: www.mprize.org ) was started. I am so tired of seeing press releases that raise hopes and go nowhere. Engineering please! Results please!

    8. Re:I dunno... by wirelessbuzzers · · Score: 1

      Look. Killing certain human cells while not killing all the rest of the cells is hard. It's a lot harder than killing a foreign pathogen without killing the human, which is already a lot harder than, say, rebooting a server or modifying a Perl script.

      Wow. Even with Perl 6 on the horizon, it doesn't look like the development community is ready to face the challenge of modifying a Perl script... is there any hope?

      --
      I hereby place the above post in the public domain.
    9. Re:I dunno... by ebuck · · Score: 5, Informative

      Perhaps it's a fundamental flaw in news reporting and how it rarely interacts well with scientific researchers that explain your jaded state.

      For a number of years, I worked in biological research, and twice I had the (dis)pleasure of interacting with reporters.

      If you tell them there is an observed improvement in 15% of all cases, then it's a cure. If you tell them there is a statistical corelation, then it "causes". If you tell them about the science, they will latch onto the most trivial detail and make it the entire point of your research effort.

      It's because most Science doesn't make good news. Good news (at least as it seems to be presented these days) gives the audience the aura of understanding without any actual understanding. In other words, good news asks the audience to learn almost nothing, but be entertained nonetheless.

      To prove my point, cancer is the misbehavior of the patient's own cells, yet nearly everyone refers to it as an item that is "caught" like a transmittable disease, and "cured" like a bacterial infection. Non-scientists rarely differentiate between the reasons why our cells misbehave, instead they concentrate on where the misbehaving cells are located. Finally, people tend to totally ignore the effects of known carcinogens because they have been bombared with so much bad news that started off as:

      When rats eat a diet of 80% fat, they have a 12% higher risk of contracting a cancer over a 3 year lifespan, 40% of those cases are self-arresting producing only benign tumors.

      becomes:

      Scientists find that diets high in fat significantly increase the risk of cancer. People who eat pizza, french-fries, and mayonnaise are at risk, and are 60% more likely to die. So it's time to stock up on those veggies.

      No mention that it's rats, not people. No mention that it's a lifetime diet of 80% fat. No mention that it only affects 12% of the rat population studied. No mention that 60% of the affected die, leading to an increase of mortailty of only 8% or so.

      Sometimes (just like in my example) they do it so badly that they have internal logical errors in their own reporting. 60% more likely to die (as opposed to 100% certainty that we will eventually die).

      So be skeptical, but please don't be skeptical of the science, unless you are one of the few people who actually bother to read the publications without the mind-numbing news filter placed on top of it.

    10. Re:I dunno... by Anonymous Coward · · Score: 0

      Antibiotics were invented before the FDA and the 10 year process of testing medicine before making it available.

      Meanwhile, people died from eating various forms of the mold until they figured out just what it was that was killing off the bacteria without poisoning the person.

      At least I'm glad that the FDA requires that the drug companies prove the drug works before making me pay $1000 a month to be the guinea pig for something that my kids discover after I died was actually the placebo.

    11. Re:I dunno... by Otter · · Score: 2, Funny
      ... is there any hope?

      Yes. Ruby on Rails. I hear it cures cancer, too.

    12. Re:I dunno... by Anonymous Coward · · Score: 0

      Yep... it certanly is unwise to potentally kill someone with an experimental cure when they are going to die in a few years from what you are trying to cure.

      Im fine with the FDA takeing 10 years to ok cough medicine, but when it comes to testing drugs for terminal diseases, then they are being fools to have the process take that long. Just cover the drug companies ass with some HEFTY anti liability contracts.

      Besides, there are now perscription ALLERGY medicines that acording to the comercials have the rare side effect of DEATH among others. But then on the other hand the supreme court has ruled that doctors cant evern perscribe drugs that aleiviate the problems that come from chemo therapy, so why am I thinking logically about the medical research world?

    13. Re:I dunno... by porcupine8 · · Score: 1
      Survival rates are up, sure, but most people are still dying and these conditions are still considered more or less terminal.

      Not all cancers, though. There are some with an 85%+ cure rate. Many people forget that it's very unlikely we'll ever "cure cancer" - every one is a different disease, we have to cure them one at a time. And we *have* had success with some of them.

      Thirty years ago, Hodgkin's was a death sentence, it had less than a 30% survival rate. Now their main problem is getting new treatments with less long-term side effects because 40% of Hodgkin's patients are under 35 and will live to deal with the long-term effects. Progress does happen.

      --
      Warning: Apple/Nintendo fangirl. Likes her electronics cute & cuddly. May be rabid.
    14. Re:I dunno... by gstoddart · · Score: 1
      Look. Killing certain human cells while not killing all the rest of the cells is hard. It's a lot harder than killing a foreign pathogen without killing the human, which is already a lot harder than, say, rebooting a server or modifying a Perl script.

      Well, with the human body some experimentation and consulting with a text book will tell you what is actually happening and what is going wrong.

      Modifying the perl script is often a lot harder, because it's function is so opaque. :-P

      --
      Lost at C:>. Found at C.
    15. Re:I dunno... by lelitsch · · Score: 1

      In the same way antibiotics don't cure all infectous diseases, one cancer treatment doesn't cure all cancers.

      Over the last decade, there have been huge successes in curing a number of cancers. One example is hairy cell leukemia which used to be a death sentence. In a recent study, only 2 out of 250 patients who were medicated with pentostatin died in the 9 years after the initial treatment, while over 170 were completely cancer free 5 years after the treatment started. That is a 9 year survival rate of over 99%, which IMO is pretty good.

    16. Re:I dunno... by Anonymous Coward · · Score: 0

      Look. Killing certain human cells while not killing all the rest of the cells is hard. It's a lot harder than killing a foreign pathogen without killing the human, which is already a lot harder than, say, rebooting a server or modifying a Perl script.

      This goes down as my favorite Slashdot Smackdown of all time! With so many idiots posting on this story, it's awesome to see a low-UID slashdotter come in and take them to task. Now in the future, please keep reason and facts out of these discussions!

    17. Re:I dunno... by Dread_ed · · Score: 2, Informative

      "And yet, we don't really seem to see masses of cancer patients getting cured outside these laboratory studies"

      Many more people are being helped each year than the last. Unfortunately, new ideas are sometimes deadends that end up helping no one or having such bad effects that they are worse than the disease. Other treatments are so narrow in their aplication that you have to have certain kind of cancer for it to be expected to work. Progress is being made though, more and more each year.

      Case in point:

      My step-grandfather started having problems with the hiccups about three years ago. At first they went on for a few hours at a time. Later, he was even doing it while he slept, continuously for months. The constant pain and exaustion (yes, EXAUSTION from hiccups) finally overcame his reticence to see a doctor. They did some tests, then more and more tests, and finally an MRI. They found inoperable cancer on/in his spine.

      A few weeks later he is at MD Anderson in Houston and they are trying an new treatment on him. They took a biopsy of some of the cancer and used it to make a vaccine. He stayed in Houston for about 6 months, had some minor chemo followups, some checkups, and then went home.

      Complete remission was and still is the diagnosis. And the hiccups went away!

      The problem with cancer is that cancer cells have similar reactive profiles and vulnerabilities to healthy cells. Finding the chink in the armor of the cancer that dosen't exist in the healthy cells is the big problem. Reaserchers are getting better and better at this (see the above vaccine example) but there are so many different kinds of cancer, with accompanying different vulnerabilities and minor variances from healthy cells, that it will take quite a bit of time to find and exploit them all.

      In some cases even the methodology of treatment had to be fundamentally different They told my grandfather that he was lucky to have the certain kind of cancer that he had as it was one that was potentially treatable with the vaccine therapy.

      I think that the basic health of the individual comes into play as well. Many people develop cancer in the twilight years of their lives. Their waning virility may make it difficult to enact a cure, regardless of the potency of the medication.

      Regardless of the obstacles, had my grandfather gotten sick about 8 months before he did, there would have been no chance of stopping his cancer in time. There was no trial going then and this particular treatment was not available to humans at all. Given time to grow he would have been killed or paralyzed by his cancer. So ya, doctors are making progress, it may seem slow, but not to my grandfather. It was more like just in time, for him.

      --
      When the only tool you have is a claw hammer every problem starts to look like the back of someone's skull.
    18. Re:I dunno... by Strontium-90 · · Score: 1

      There's a big difference between a revolutionary breakthrough that can lead to a cure and the cure itself. The media generally doesn't understand this difference, or doesn't care to make the distinction. Even when you nail down what chemicals are important for treating a given disease there is still much work to be done. Perhaps the potential drug that you've developed has bad interactions (side effects) in other parts of the body, so you need to modify the molecule slightly so that it doesn't have those interactions but is still effective. For instance, it'd be a shame if your cure for cancer caused heart attacks in 50% of patients. Modifying the drug can take several years, even decades.

      Also, don't forget about clinical trials. Once you have something that looks like it might be a cure there are still questions like: "What dosage is needed?", "Over what period of time does the drug need to be administered?", etc. These aren't questions that are answered in weeks or months, but in years. And until these questions are answered, you'll only find these drugs as experimental treatments and clinical trials, not as marketed drugs.

      Science is a slow process, and when you're talking about putting foreign chemicals into the body to cause major changes, it pays to be thorough in your testing. And yes, there are always false leads in science. Many things that look good initially end up not working, sometimes due to side effects, sometimes because they just can't be made to work on a large scale, or perhaps because it simply isn't cost effective. And by cost effective I'm saying that there are issues of breaking even, not that the drug won't bring in millions. The pharmaceutical industry, just like any other industry, has to obey the laws of economics.

      Rest assured, assuming that a cure is possible, we will have cures for most cancers and AIDS within the next few decades, at the latest. I know that saying "be patient" isn't very helpful for someone with cancer or AIDS, but lots of people are working very hard to beat these diseases.

    19. Re:I dunno... by Stauf · · Score: 1

      Look. Killing certain human cells while not killing all the rest of the cells is hard. It's a lot harder than killing a foreign pathogen without killing the human, which is already a lot harder than, say, rebooting a server or modifying a Perl script.

      Medicine is a completely different field to Information Technology - it's similar to comparing an english essay with a mathematical proof. And not only that - you're comparing the most basic of Computer Science with the most complex of medicine. Is injecting something into a bunch of rats then measuring the results harder then designing an O(1) scheduler? Is theorising a drug based on complex bio-chemical equations harder then hitting 'reboot'?

      There isn't really an easy answer, but I think that 'which is already a lot harder than, say, rebooting a server or modifying a Perl script' is a vast simplification. Some medicine is easy, some Comp. Sci. is hard and vice-versa. Of course, I believe that medicine is probably a more useful area of study overall - I'd rather live in a pre-industrial society free of disease then a modern one where we have horrible super-virii - but I don't think you can just claim that medicine is harder.

    20. Re:I dunno... by Anonymous Coward · · Score: 0

      It's not just official news reports that hype shit up, its slashdot submitters as well. Just look at some of the article summaries.

  13. Slashfarked! by Tackhead · · Score: 1
    > I guess it's going to be a long weekend of explaing WTF is up with the pinapples slices in my hefeweizen.

    Scientists discover new substances that offer progress in the fight against cancer and HIV.

    Still no cure for bartenders who put fruit in beer.

    Zonk submitted these stories to Fark many hours ago, with less-funny headlines?

  14. Cure? by part_of_you · · Score: 1, Funny
    I thought Magic Johnson already beat AIDS.

    ...oh wait, now I understand, he has a MAGIC JOHNSON!!! I'm always the last to figure it out.

    1. Re:Cure? by Anonymous Coward · · Score: 0

      Last time I saw Magic Johnson, he looked like a fat chipmunk.

      Many kids don't think he even has aids.

      Tin Foil Hats Now On Sale Toys R US

  15. Breakthrough?*Yawn* by InternationalCow · · Score: 0, Flamebait

    Slashdot must be a little starved for news these days. I didn't even bother to read the HIV paper. There are so many compounds that can block entry of HIV into its target cells that one new one is not exactly a breakthrough. Ditto for the bromelaine - there are many many compounds that will kill cancer in vitro. How everything will work in the actual patient, that's something else entirely. Please wake me up when some realistic coverage of modern drug research is posted.

    --
    ----- One learns to itch where one can scratch.
    1. Re:Breakthrough?*Yawn* by Daniel_Staal · · Score: 2, Informative

      Maybe you should have read the paper: They've already done a small-scale clinical trial.

      --
      'Sensible' is a curse word.
    2. Re:Breakthrough?*Yawn* by secondsun · · Score: 3, Informative

      How everything will work in the actual patient...

      This HIV study was a 40 patient clinical trial. Pretty damn close to actual patients if you ask me.

      --
      There is nothing wrong with being gay. It's getting caught where the trouble lies.
    3. Re:Breakthrough?*Yawn* by InternationalCow · · Score: 1

      Well, I read it. If you do read it well you will see that they have not done a clinical trial. They state that it works "in patients". That means that they may as well have taken blood from these people and worked with the cells from it. Sorry, not convincing. The definition of a "clinical trial" is rather more stringent. Both of these "news" items are overenthusiastic overhyped press releases meant to help raise funds. I know as I've made such releases myself (the last one was when we found a gene involved in a rare hair disorder, we released it to the press as a "baldness gene" I spent a day in various radio studios after that).

      --
      ----- One learns to itch where one can scratch.
    4. Re:Breakthrough?*Yawn* by Anonymous Coward · · Score: 0

      likewise.. it seems that every year or two I hear about some new thing in R&D that looks like a cancer cure. And I think how cool it is that I got to be alive to see the cure. But then I never hear about it again. Not that I could tell, on my own, whether something is worth getting worked up about.

    5. Re:Breakthrough?*Yawn* by Daniel_Staal · · Score: 1

      Interesting. Thanks for clearing up that piece of medical marketing jargon. I'll have to remember it; there is way to much of that particular species of jargon in use.

      --
      'Sensible' is a curse word.
    6. Re:Breakthrough?*Yawn* by InternationalCow · · Score: 2

      Again, you fail to read this properly. I do not believe for one second that a compound that has not passed beyond the letter+digit naming stage has been used in 40 patients, in the sense of systemic administration. There's no way that you can get away with this from an ethics point of view now that we have HAART. I believe it when they give actual details. Perhaps it was a phase I toxicity study. That is NOT a trial! As said in my other post, they may as well have taken material from 40 patients and tried it on that. The present message is just hype, hype, hype.

      --
      ----- One learns to itch where one can scratch.
    7. Re:Breakthrough?*Yawn* by juanfe · · Score: 2, Interesting

      Um... no. see below:

      New drug blocks HIV from entering human cells

      http://www.hindustantimes.com/news/181_1423753,0 05 0.htm%5D
      ">Indo-Asian News Service
      Tokyo, July 7, 2005

      "A new drug that blocks HIV virus from entering human cells and causes almost no side effects has been developed by Japanese researchers.
      The drug, code named AK602, was tried on 40 AIDS patients in the US and almost no side effect was found.

      "When patients took 0.02 ounces of AK602 twice a day for 10 days the HIV dropped to an average of one per cent, according to a research team led by Hiroaki Mitsuya of Kumamoto University.

      "Current AIDS medications often lose their effectiveness after a few days due to the virus' resistance, but the AK602 reacts to human cells instead of attacking the virus, said Mitsuya. [...]"

      Under current HAART treatment, it takes months for HIV viral load to go down that quickly, and side effects under current meds are not negligible (high cholesterol, weird fat distribution, major depression, intense diarrhoea...)

      --
      ***Foucault is watching you..***
  16. Implications by Anonymous Coward · · Score: 0

    Does this mean that, at least in theory, I could cure myself of cancer just by eating a lot of pineapple? How much would I need to consume?

  17. The Difference by Valacosa · · Score: 1

    So, if the drug prevents HIV from entering cells, what's the difference between that and immunity? My guess is the virus can still enter the bloodstream...

    Making a vaccine is one thing, getting it to Africa is another thing entirely. Last I read, drugs exist to treat the "Sleeping Sickness" but aren't readily available because it's not profitable to sell them to the poor Africans...

    --
    "Live as if you'll die tomorrow." Ridiculous. You could die later today.
    1. Re:The Difference by Reverend528 · · Score: 3, Informative
      My guess is the virus can still enter the bloodstream...

      Yes, but as a virus, it's unable to reproduce if it cannot enter the cells.

    2. Re:The Difference by Hachey · · Score: 2, Informative

      It inhibits CCR5 interactions. Thats strickly macrophages - open still are CXCR4 interactions (T Helper Cells) and cell-to-cell mediation. Autoimmune reponse still cause the body to kill itself if the virus is present, and there is also the lymph system and the brain (it crosses the blood/brain barrier).

      Plus, HIV can lie latent for many years.

      It's one nasty virus. This drug does NOT make you immune to HIV.

      AIDS


      --
      Check out the Uncyclopedia.org :
      The only wiki source for politically incorrect non-information about things like Kitten Huffing and Pong! the Movie !

      --
      Please allow me to hate the creator of the 120-character limit: *HATES*. Thank you.
  18. I love "almost no side effects"... by JargonScott · · Score: 5, Funny

    That's such a great cover. I wonder what the "almost no" side effects are, like "all life as you know it stopping instantaneously and every molecule in your body exploding at the speed of light".

    --
    Nuke Gay Whales for Jesus.
    1. Re:I love "almost no side effects"... by pizen · · Score: 1

      Important safety tip. Thanks, Egon.

    2. Re:I love "almost no side effects"... by centauri · · Score: 1

      *gasp*

      Total protonic reversal....

      --
      Don't blame me, I voted for Durga.
    3. Re:I love "almost no side effects"... by xMilkmanDanx · · Score: 2, Funny

      May cause drowsiness, stomach ache, dizziness, uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs; fever; muscle rigidity; sweating; irregular pulse; or fast or irregular heartbeats. Avoid exposure to sunlight or UV rays. Use caution in hot weather and during exercise. Drink plenty of fluids. Use caution when driving, operating machinery, or performing other hazardous activities. Some patients have experienced depression (including feelings of sadness, irritability, unusual tiredness, trouble concentrating, and loss of appetite) and suicidal thoughts and/or behavior during, and soon after stopping, treatment with Accutane. Notify your doctor immediately if you begin to experience signs of depression or if you begin to have thoughts about taking your own life during or shortly following treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission. May cause internal bleeding, difficulty urinating and in certain rare instances, death.

    4. Re:I love "almost no side effects"... by ebuck · · Score: 2, Funny

      I think "almost no side effects" in this case is about the equivalent effect of taking sugar pills.

      Well, a lot of sugar pills.

      About 890,450 sugar pills (appx. 80 lbs 7 oz), to be exact.

      Taken rapidly, with no water.

      Over the span of approximately 3 minutes 12 seconds.

      It's not pretty, sort of like an explosion from within.

    5. Re:I love "almost no side effects"... by bshroyer · · Score: 1

      That would be bad, right?

      --
      The cure for cancer is coming: Reovirus
    6. Re:I love "almost no side effects"... by blincoln · · Score: 1

      during, and soon after stopping, treatment with Accutane

      Instead of giving people a 2cm-thick booklet full of warnings when they're prescribed Accutane, it should just be a post-it that says "this will fuck you up in ways you never would have thought posssible. Deal with it, because if you mention any of them to your doctor your prescription will be revoked and you'll have that face covered in giant zits for the rest of your life. PS: try not to kill yourself, and don't get pregnant unless you're an HR Giger fan."

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    7. Re:I love "almost no side effects"... by xMilkmanDanx · · Score: 1

      Actually that wasn't my intent to leave that in there. I grabbed some actual side effect warnings and thru in a few of my own (like 5). Sad part, I only combined the side effects of two different drugs...

  19. Skepticism is in order by jvagner · · Score: 1, Interesting

    Anyone interested in AIDS science, who wonders why HIV is so misunderstood, would do well to start here and read a bit:

    http://aliveandwell.org/

    1. Re:Skepticism is in order by cbnewman · · Score: 5, Informative

      yikes. having personally seen the effects of HIV infection and AIDS in people who subscribe to the AIDS Denialist school of thought, i felt compelled to reply to this posting.

      bottom line:

      1. CD4+ T-lymhocyte counts and HIV viral loads have been negatively and positively (respectively) correlated with survival in virtually every patient population ever studied.

      2.highly active anti-retroviral therapy (HAART) has been shown to significantly reduce mortality in HIV-infected individuals.

      we practice evidence-based medicine in the united states. you can try to poke holes in the virology if you want to (i'm not a virologist) but you can't argue with epidemiology.

      the theory that HIV is the causative pathogen in AIDS has not been disproven in any peer-reviewed publication that i have ever seen.

      we know how to treat these patients and turn AIDS into a chronic rather than a fatal illness.

      here is a more complete resource on the debate.

    2. Re:Skepticism is in order by Anonymous Coward · · Score: 0

      Right, now let's just use homeopathy and acupuncture to cure AIDS. That site is dangerous.

    3. Re:Skepticism is in order by kryshnysh · · Score: 1

      I moderated you up but had no more Mod points, so I'm saying this: MOD PARENT UP!

      Whether you agree with the denialist school of thought or not, you should definitely be presenting both arguments, not just one biased website.

    4. Re:Skepticism is in order by ckedge · · Score: 1

      .
      So I perused through a few of the related pages. I kept coming across things like the following:

      a) Badly formed references - for example Reference 62. Upon careful review they are NOT quoting a specific part of a WHO document printed by Harvard, but rather they are quoting part of a SELF PUBLISHED un-recognized journal published by a Mr. Charles Geshekter - a HISTORY professor.

      b) Statements which say exactly the opposite or something comletely different than what the actual reference provides evidence of. For example the following quote from a Charles Geshekter article: "The latest study shows that an HIV-negative woman converts to positive on average only after one thousand unprotected contacts with a positive man, and a negative man becomes positive on average only after eight thousand contacts with a positive woman.(3)" The actual reference was a study about sex WITH A CONDOM. Not unprotected sex as inferred.

      I also keep coming across websites by "Dr"'s who's education is a "B.A. in Comparative Religion" and "M.A. in Humanities"...
      .

  20. News from Fark, Stuff We Already Know by Gothmolly · · Score: 1, Informative
    --
    I want to delete my account but Slashdot doesn't allow it.
  21. Dole! by Grendel+Drago · · Score: 1

    He's clearly the ripe man for the job.

    --
    Laws do not persuade just because they threaten. --Seneca
    1. Re:Dole! by MynockGuano · · Score: 1

      ba-dum *ching*

  22. Great.... by Iphtashu+Fitz · · Score: 0, Redundant

    Now I'm gonna start getting spam from Dole touting their miracle cancer cure...

  23. Pineapples? by rpsoucy · · Score: 1

    Well, cancer stuff is cool and all, and I know you all love to comment on anything involving fruit... but I think the AIDS blocking research is a bit more interesting, personally. Not that I have AIDS or anything, but it would certainly be nice to be rid of it, especially in Africa.

    1. Re:Pineapples? by Anonymous Coward · · Score: 0

      Yeah.. Why Pineapples? I can't stand pineapples. Why not bananas or something else?

    2. Re:Pineapples? by Anonymous Coward · · Score: 0

      Fighting AIDS isn't as important in Africa, as it is in Eastern Europe, India and China. The rate of infection in Africa has decreased, because the infection rate has surpassed its peak... In Africa, the number of AIDS-related deaths each year now outnumbers the number of new HIV cases. This is because of the slow response to fighting AIDS in Africa... if billions of $ were spent fighting AIDS in Africa a decade ago, then we would have a few million fewer HIV infections and could have had a noticeable effect.

      It is currently more important to slow the rapid outbreaks in Eastern Europe, India and China... The number of HIV-infected will likely surpass 100+ million in those regions alone, if we let it spread out of control like we had in Africa...

  24. Pineapple molecules by crimoid · · Score: 3, Funny

    "pineapple molecules"

    Pineapples have molecules of their own?

    1. Re:Pineapple molecules by Anonymous Coward · · Score: 0

      This is news? Bromelain was shown to have anti-cancer properties decades ago. A search on "Bromelain Cancer" at Pubmed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) turns up 69 hits, some going back to 1968.

    2. Re:Pineapple molecules by Anonymous Coward · · Score: 0

      It must be the spiny outer layers of the pineapple molecules that kill the cancer...

    3. Re:Pineapple molecules by Stauf · · Score: 1

      Maybe a pineapple is just a big Bucky Ball?

    4. Re:Pineapple molecules by ExoticMandibles · · Score: 1

      Do you suggest that pineapples might be made out of something besides molecules?

    5. Re:Pineapple molecules by dbIII · · Score: 1
      Pineapples have molecules of their own?
      Yes, made up of something surprisingly similar to beer atoms.
  25. AIDS is not a virus by mikeormike · · Score: 2, Informative

    "AIDS virus"? AIDS is not a virus

    HIV - Human Immunodeficiency Virus
    AIDS - Acquired Immune Deficiency Syndrome

    http://en.wikipedia.org/wiki/Hiv
    http://en.wikipedia.org/wiki/AIDS

    1. Re:AIDS is not a virus by geon · · Score: 5, Insightful

      So, I guess the flu virus ain't a virus either, under the reasoning you exhibit above?

      AIDS is not a virus, but "AIDS virus" simply means "the virus that causes AIDS", just as "flu virus" means "the virus that causes the flu". Of course, the actual _name_ of the "AIDS virus" is HIV.

      The person writing the phrase "AIDS virus" knows what he means, as does everyone reading the phrase. There's not even anything misleading about it: AIDS referes to a syndrome which is caused by infection by HIV, and the phrase AIDS virus is just a reference to human immunodeficiency virus - nothing misleading about it. While I would prefer that someone refer to HIV as simply HIV, calling it the AIDS virus is not wrong.

      "AIDS vaccine" is slightly misleading, for the reason you give, but it is also a case of everyone involved knowing precisely what is meant, and no actual confusion is likely to result.

      +5 informative my arse. The above is not unlike complaining about the usage of who versus whom in some random sentence.

      (This post brought to you by a lack of coffee and a distaste for grammar fascism and related disorders.)

    2. Re:AIDS is not a virus by DoofusOfDeath · · Score: 1

      The distinction between HIV and AIDS is pointless in most conversations.

    3. Re:AIDS is not a virus by midnightblaze · · Score: 1

      Well, "AIDS virus" can just be a short form of "virus that causes AIDS." English is a very fluid and inexact language. Not at all like programming. And it can be nice that way. Poetry, for example.

      I am a programmer, I am a very anal person, and yet, I don't feel uncomfortable when I, or others say "AIDS virus."

    4. Re:AIDS is not a virus by benzapp · · Score: 1

      Having HIV doesn't necessarily mean you will manifest AIDS, and having AIDS doesn't mean you necessarily have HIV.

      If we could take HIV, stick in someone and then have them manifest AIDS, we wouldn't be having this conversation. HIV and AIDS are properly separated in discourse specifically because they aren't always related.

      --
      I don't read or respond to AC posts
    5. Re:AIDS is not a virus by hacker · · Score: 1
      "AIDS is not a virus, but "AIDS virus" simply means "the virus that causes AIDS", just as "flu virus" means "the virus that causes the flu". Of course, the actual _name_ of the "AIDS virus" is HIV."

      Not entirely true... you can get AIDS from quite a few places, many of which are completely unrelated to HIV. High dosages of the drug Prednisone for example, can cause patients to acquire AIDS (which later goes away as the dose is lowered again). There is quite a bit of research on this and similar issues.

      HIV isn't the only thing that causes AIDS. I just wanted add that correction to your post.

    6. Re:AIDS is not a virus by joshv · · Score: 1

      Yes, but one can have all of the clinical symptoms of AIDS while testing negative for the HIV virus. http://www.autoimmune.com/Non-HIVAIDSGen.html

      Additionally there are many people called 'long term non-progressors' who test positive for HIV and have as of yet not presented any clinical symptoms of AIDS. Some going on 20 years now.

      So HIV is not the 'AIDS virus', as it does not appear to cause AIDS in all cases where it is present, and not all cases of AIDS are marked by the presence of HIV. At best one can say the presence of HIV is strongly coorelated with AIDS symptoms.

  26. Pineapples? by Anonymous Coward · · Score: 0

    Why pineapples?

  27. AIDS virus? by Cocoronixx · · Score: 1, Redundant

    FWIW, HIV is the virus, AIDS is a descryption of a condition when your white blood cells drop below a certain level.

    --
    "Obscenity is the crutch of the inarticulate motherfucker." - cloak42
    1. Re:AIDS virus? by tgd · · Score: 0, Offtopic

      FWIW, encryption has a "Y", description has an "I".

      Since we're on the topic of FWIW's.

    2. Re:AIDS virus? by Cocoronixx · · Score: 0, Troll

      FWIW, go fuck yourself.

      --
      "Obscenity is the crutch of the inarticulate motherfucker." - cloak42
  28. mmm, pineapple extract. . . by Sialagogue · · Score: 1


    If we're going to express our support for getting this research funded do we all have to wear little paper umbrellas on our lapels?

    --
    The only acceptable defense of scientific results is to say that they were the product of the Scientific Method.
  29. successful summit by Anonymous Coward · · Score: 0

    This was obviously a result of the successful G8 summit!

    The terrorists are defeated!!1 :)

  30. Radio ad? by NitricEster79 · · Score: 1

    Local to St. louis here. There has been an ad on the radio about an AIDS vaccine being tested here. I was wondering if anyone else knew anything about it. The ad is for volenteers to go in to be a part of the study...you can't get AIDS from it and yadda yadda crap. Why exactly do we have fifty billion research companies all looking for the same answer and none of them are working together on it?

    1. Re:Radio ad? by Anonymous Coward · · Score: 0

      Why? Greed.
      Until goals for humanity become more important than money, only then will great problems like Cancer and aids will be conquered.

      Look at what's happening in SW: M$ is all about $ and nobody cares about Windows unless it affects their bottom line. Not so for Linux (and MAC to some extent).

      MPAA is all about $, too and just now it's starting to hurt them. They don't care about the story, only sequels

  31. Aids Vaccination? by Anonymous Coward · · Score: 3, Funny

    Bad news for Trojan good news for Hasboro.

    1. Re:Aids Vaccination? by rsynnott · · Score: 1

      Well, hopefully people won't stop taking sensible precautions just cause of a HIV vaccine. There're other things out there; HepC, in particular, is nasty.

      --
      Me (Blog)
  32. Malaria! by Grendel+Drago · · Score: 2, Informative

    Malaria kills about a million Africans a year, but we hear less about it and more about HIV, despite the massive funding gap for malaria. Especially since there are cheap and effective measures against malaria which are not used because of a simple lack of funding.

    Hey hippies---are you happy you got DDT banned now? All those dead Africans say thank you!

    But seriously, there are some moderately effective drugs, and treated mosquito nets (covered in a bug-eating fungus, apparently) have been used to great effect.

    --grendel drago

    --
    Laws do not persuade just because they threaten. --Seneca
  33. Learn to spell. by Anonymous Coward · · Score: 0

    If you're dating an immunologist, you ought to be smart enough to spell "lose".

  34. Oblig. Simpsons quote by SeekerDarksteel · · Score: 0

    "Ah beer. The cause of, and solution to, all of life's problems."

    Homer was right after all.

    --
    The laws of probability forbid it!
  35. Re:Yes but... by Anonymous Coward · · Score: 0

    Good one!

  36. Not every disease... by Anonymous Coward · · Score: 0

    ... can be cured by a single pill. Some of them, such as diabetes, require external supplements for what the body can't create. Granted, things like stem-cell research can lead to the ability to (re)grow islet cells to make one's own insulin, but otherwise...

    Since people get all bent out of shape about GM foods, I doubt they'll be too interested in GM people. Cuz that's what a gene-based cure is - get the body to do something it can't do now.

    Or, will people take the cure and not the tomatoes?

    1. Re:Not every disease... by Anonymous Coward · · Score: 0

      But aren't we all GM people now?

      We all get the employee discount.

  37. Known by Anonymous Coward · · Score: 0

    The effect of enzymes on cancer has been
    known and in use by the alternative
    health community for decades.

    Look up Wobenzym N and see the history.

  38. I predict by VolciMaster · · Score: 1

    shares of Dole will skyrocket on this.

  39. and the winner is... by slashdotnickname · · Score: 1

    humans!

    for most-effort-put-into-solving-a-problem-that-alread y-had-a-simple-solution-since-day-one, i.e. quit screwing around

    now for the next category, most-bodily-gases-expelled-in-a-minute, the winner is...

    the Verticons!

  40. Double Benefit by Foolomon · · Score: 3, Funny
    Not only does it attack cancer, but by drinking pineapple juice I can taste better too!

    I wonder how my imaginary girlfriend will feel about this...

    1. Re:Double Benefit by Anonymous Coward · · Score: 0

      > Not only does it attack cancer, but by
      > drinking pineapple juice I can taste better too!
      >
      > I wonder how my imaginary girlfriend will feel about this...

      She doesn't care because she refuses to ...you know, do the thing that would make her care how you taste.

  41. Only a drug can treat an illness by vettemph · · Score: 2, Insightful

    >if it succeeds it will seek a commercial partner to develop a drug that could be used in human clinical trials.

    What they are saying is, "Unless we find a patentable and highly profitable way to secure this discovery, We won't bother."

    I welcome the return of more natural remedies. These drug companies aren't happy until they turn a natural remedy into something with side effects.

    --
    The government which is strong enough to protect you from everything is strong enough to take everything from you.
    1. Re:Only a drug can treat an illness by blincoln · · Score: 1

      What they are saying is, "Unless we find a patentable and highly profitable way to secure this discovery, We won't bother."

      They don't have a choice, unfortunately. Getting approval to release a drug is stupidly expensive in most industrialized countries.

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
  42. Re:Yes but... by TripMaster+Monkey · · Score: 0, Offtopic


    They're working on one right now...it's called 'Christian Fundamentalism'...preliminary trials have shown it to be moderately effective against Islam, but studies suggest that this 'cure' may be even more dangerous than the 'disease'.

    --
    ____

    ~ |rip/\/\aster /\/\onkey

  43. Who lives in a pineapple under the sea? by bujoojoo · · Score: 2, Funny

    This just in: SpongeBob is celebrating quietly with Tinky Winky at his home in Bikini Bottom.

    --
    This space for rent
  44. Thanks, dumbass. by burndive · · Score: 1
    You're right. AIDS is the syndrome, HIV is the Virus.

    However, your anal objection to the phrase "AIDS virus" in completely unfounded. HIV is the virus that causes AIDS. AIDS uniquely identifies this particular virus, and so in English, the phrase "the virus that causes AIDS" can be shortened to "the AIDS virus" without any loss of meaning or correctness.

    In fact, the phrase was probably intentionally chosen to intensify (or sensationalize) the mental image conveyed by the story.

    --
    ...because "hacker" sounds way sexier than "code drone."
  45. -1, Redundant by Anonymous Coward · · Score: 0

    If I said "Tonka truck" I suppose you would tell me Tonka isn't a truck, it's a company.

    "AIDS virus" is a common synonym for HIV. To put it in other words: "the virus that causes AIDS".

  46. Why? Capitalism. by John+Nowak · · Score: 1

    I wonder how long it will be until the world begins to wake up and realize...

    1. Re:Why? Capitalism. by porcupine8 · · Score: 1

      Yeah, Socialism has done wonders for Canada's drug industry! Look at the innovations coming out of there!

      --
      Warning: Apple/Nintendo fangirl. Likes her electronics cute & cuddly. May be rabid.
  47. Stupid slashdot editors by Anonymous Coward · · Score: 0

    Why is this news? Scientists continually find all sorts of things which look good in the biology lab but don't work in real life.

    First, the Yahoo news article does not a cite where the findings were published, if at all. Did Zonk try to find the actual reference? I bet.

    Second, we know lots of things that cure cancer in test tubes, but fail miserably when it comes to working in people. The article states they haven't even tried any clinical trials yet. My guess is that it won't work when they actually try to test it in people, if for no other reason than pineapples are pretty popular and we would have seen an effect on cancer rates in epidimeological studies long ago.

    This is good example of how the slashdot editoral board is pretty much comprised of a bunch of computer geeks who've hardly ever cracked open a science textbook in their lives, much less worked in a real lab.

    Ever think about getting some editors on this site who actually have taken a real science course or two?

  48. Oh, good! Another blithering, ignorant ideologue! by Anonymous Coward · · Score: 0, Insightful
    Wow. You might be a *complete* dumbass, but it will take scientific instrumentality to see how close to 100% you really are. Probably like 99.999999%

    Let us know how your herbs and ritual dances work on your cancer tumors, okay, Sport?

  49. Nah. He just has a sit load of fingers. by crovira · · Score: 1

    You don't want to know what he pays for a pair of gloves.

    --
    MSBPodcast.com The opinions expressed here are my own. If you don't like 'em... Think up your own stuff.
  50. In the Petri dish, it's very simple by paiute · · Score: 3, Insightful

    Back in the day, when one wrote a NSF grant proposal to fund the isolation, identification and synthesis of natural product, one always included prominently the fact that in vitro - in a Petri dish, the desired compound killed cancer cells. Hey presto - now it's an NIH grant proposal as well. The keywords antitumor, anticancer, etc. in the title were magic.

    Of course, these never became actual medicines. One realized over time that a sledgehammer will kill cancer cells in a Petri dish. As will a stick of dynamite or a teaspoonful of sodium cyanide or just driving over it with a Buick.

    Once you take into account that human biological system is slightly more complex than the Petri dish system, you will be less excited by the breathless prose of headline writers.

    --
    If Slashdot were chemistry it would look like this:Cadaverine
    1. Re:In the Petri dish, it's very simple by hab136 · · Score: 1
      One realized over time that a sledgehammer will kill cancer cells in a Petri dish. As will a stick of dynamite or a teaspoonful of sodium cyanide or just driving over it with a Buick.

      The new Buick 2006 CancerKiller! Drive one home today!

    2. Re:In the Petri dish, it's very simple by Anonymous Coward · · Score: 0

      One realized over time that a sledgehammer will kill cancer cells in a Petri dish. As will a stick of dynamite or a teaspoonful of sodium cyanide or just driving over it with a Buick.

      DRIVING A BUICK FOUND TO CURE CANCER! GM SHARES DOUBLE OVERNIGHT!

  51. Rich White Americans don't get Malaria by davidwr · · Score: 1

    Well, only those that travel to Malaria-infested parts of the world do.

    Rich White Americans DO get HIV. Expecially those with multiple sex partners.

    --
    Knowledge is how to play a game, intelligence is how to win, wisdom is knowing what game to play.
  52. C'mon folks, get real by yeastbeast · · Score: 5, Interesting

    As a biomedical researcher who has worked on cancer mechanisms in the past, I speak with some authority: these "breakthroughs" are a load of hooey. The popular press really loves it when some dinky little research group at Bumblefuck U. discovers a modest effect on cancer cells, HIV, etc. by some commonplace natural molecule. We've heard it about pineapples, green tea, broccoli, red wine, you name it. Usually these studies are conducted under extremely artificial conditions using tiny sample sizes and ambiguous assays. To be cynical, if researchers want to get a positive result, they can usually contrive some experimental condition where they'll observe said result. I read Slashdot for interesting technology items but I have been very disappointed with the caliber of the biomedical coverage. There have been a number of stunning discoveries over the last few years (two that leap to mind are microRNA-mediated viral immunity and gene regulation or epigenetic memory in plants) that never made it to Slashdot because they require more than a high school level education in biology to appreciate. Evidently, mod points don't go to people with an advanced knowledge of biology. How would you feel if all of tech stories were press releases from Microsoft?

    1. Re:C'mon folks, get real by Phil+John · · Score: 1

      two that leap to mind are microRNA-mediated viral immunity and gene regulation or epigenetic memory in plants

      That's the problem, those titles are nowhere near as snappy as "Cure for cancer and AIDS around the corner". Now, if either of them involved Natalie Portman and hot grits, then they may make it to /.

      --
      I am NaN
    2. Re:C'mon folks, get real by the_2nd_coming · · Score: 1

      a small sample size? what like 20 sample? ever heard of a t-test?

      sheesh

      --



      I am the Alpha and the Omega-3
    3. Re:C'mon folks, get real by blincoln · · Score: 1

      Evidently, mod points don't go to people with an advanced knowledge of biology.

      I've noticed an unfortunate trend that a lot of "technical" people don't have any interest in biology, as if it's an outdated science.

      Or maybe it's because it's easier to look impressive coding than genetic engineering =P.

      --
      "...always new atoms but always doing the same dance, remembering what the dance was yesterday." -Richard Feynman
    4. Re:C'mon folks, get real by Oxen · · Score: 2, Interesting

      As a fellow bio researcher, I wholeheartedly agree. The problem is that "News for Nerds" really means "News for CS Nerds". I would love a forum similar to Slashdot that was geared at the bio/med community, and I think it could really take off in the bio community. It would be so wonderful to be able to discuss current items of interest (i.e. journal publications) in a forum similar to Slashdot, but with some serious insight into the articles.

      --
      First you animate. Then you SUSPEND!!!
    5. Re:C'mon folks, get real by Anonymous Coward · · Score: 0

      What's your point? Slashdot is a electro-tech site not a biology/medical site.

      duh

    6. Re:C'mon folks, get real by Anonymous Coward · · Score: 0

      As an unix administrator and developer, I also speak with some authority: Slashdot's technical coverage isn't any better.

      Quite a few of their tech stories might as well be PR from MS.

    7. Re:C'mon folks, get real by Anonymous Coward · · Score: 0

      First of all, this is NOT a break thru. Bromelain has been known as an extremely powerfull cancer fighter among other health benifits for a very long time by nutritionalist. And it is not just a meak farse. My father has cured many people with sever cancer. My uncle who was given a few months to live from lung cancer, choose to follow my dads 'unorthodox' nutrition diet. http://www.seegerscanceranswer.com/ And guess what, that was around 6 years ago, and my uncle's cancer is gone. You still going to tell me there is nothing to this? Sorry, but I beg to differ. I have living proof in my family. And tell that to the many my father has cured using 'silly' things like pineapple.(and a large combination of other dietary changes).

    8. Re:C'mon folks, get real by Anonymous Coward · · Score: 0

      I would love a forum similar to Slashdot that was geared at the bio/med community
      __________________

      So, why don't you start one??

    9. Re:C'mon folks, get real by dbIII · · Score: 1
      The problem is that "News for Nerds" really means "News for CS Nerds"
      Considering it started as a web project by a guy whose previous web presence was themes for the enlightenment window manager and an application for the same it isn't really surprising what the focus is. It started small, a similar thing could be there for the bio/med community but too small to be found easily yet.
    10. Re:C'mon folks, get real by QuickFox · · Score: 1

      Maybe you should become an editor here.

      Or maybe you'd enjoy SciScoop more than Slashdot.

      -- Terrorism may have turned the United States into a nation of fear and aggression, but it won't succeed in Europe.

      --
      Terrorists can't threaten a country's freedom and democracy. Only lawmakers and voters can do that.
    11. Re:C'mon folks, get real by bill_mcgonigle · · Score: 1

      My uncle who was given a few months to live from lung cancer, choose to follow my dads 'unorthodox' nutrition diet. http://www.seegerscanceranswer.com/ [seegerscanceranswer.com] And guess what, that was around 6 years ago, and my uncle's cancer is gone. You still going to tell me there is nothing to this?

      Who knows? You especially, and maybe your Dad, need to take a statistics course. A sample size of 1 is too small to make any kind of determiniation.

      If your Dad is already finding willing patients, he needs to setup a clinical trial. Find 30 patients undergoing conventional treatment, and 30 following your Dad's plan and have the 30 non-conventional also be seen by regular oncologists, and track their progress over the next 5 years. Whether this is ethical or not is something to debate. Plus your Dad needs to commit to finding another line of work if things don't work out his way, or writing a book and going on a TV tour if they do.

      There's nothing to be afraid of from statistics, it often reveals truths that are hard to see. Unless you don't want people to see those truths, or course.

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
    12. Re:C'mon folks, get real by bill_mcgonigle · · Score: 1

      two that leap to mind are microRNA-mediated viral immunity and gene regulation or epigenetic memory in plants) that never made it to Slashdot

      Try posting stories over at Technocrat. The editor there has a functional brain and no Aeron chair.

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
  53. $1.00 Donations by skorpi0wnz · · Score: 1

    I'm starting on the pineapple colored wristbands. Only a dollar to support pineapple research.

  54. Look! A mindless, robotic ideologue! by Anonymous Coward · · Score: 0
    When will you one-note witless wonders ever wake up and realize that all the economic types, from Capitalism to Socialism, have stuff that actually works, and what we need is balance, and not blithering hate for one side or the other.

    We wouldn't have most of the medical science that exists today if it weren't for capitalism. No, it's not perfect, as I imply above, but this "System X is the reason for all misery in the universe" is down on the zero level of intellect.

    Ooooo! BIG EVIL CAPITALISM!!!! Grow up, you silly, uneducated fool.

    1. Re:Look! A mindless, robotic ideologue! by Anonymous Coward · · Score: 0

      I agree with you that capitalizm has given us great advances in many many fields...but at what point in time do we say that one issue or one area of research is so very important that all our efforts should be pooled together so the human race as a whole can benefit instead of just those with the money and those fortunate enough to be under the good graces of those with money.

      Surely socialism isn't warrent in say the hardware market, or software market...but when lives are at stake? I'm not saying we should have free pills that give old guys errections but things like AIDS and Cancer...

  55. HOW? by Anonymous Coward · · Score: 0

    How would you test an AIDS-type vaccine on real people? Give them the vaccine and then have them shoot up with a dirty needle? Not many volunteers for that.

    Perhaps asking for volunteers in Africa (very high AIDS rate) might work though... if a noticable decrease occurred in the test area you've got a winner...

    1. Re:HOW? by Anonymous Coward · · Score: 2, Insightful

      Maybe if you studied how biological research is done, you'd realize how easy it would be to test it. There's things called randomized clinical trials and epidemiological studies that would easily determine in a few years time whether or these things worked. But since you can't think of it, it can't be done! Whooo-hooo!

      Perhaps asking for volunteers in Africa (very high AIDS rate) might work though... if a noticable decrease occurred in the test area you've got a winner...

      Wow, are you in high school? Get a clue and take class on statistics or clinical trials in particular. You'll find well agreed upon methods that work!

  56. pineapple? by tsioc · · Score: 1

    Well this sucks, I HATE pineapples! any chance of a pill form?

    1. Re:pineapple? by WillAffleckUW · · Score: 1

      Well this sucks, I HATE pineapples! any chance of a pill form?

      Sure, we have a nifty pill, called PlaCeBo, but we're only issuing it to people who believe in Intelligent Design.

      --
      -- Tigger warning: This post may contain tiggers! --
    2. Re:pineapple? by Sethosayher · · Score: 1

      Dude! How can you hate pineapples? Sure...they can poke an eye out, but you don't eat the skin silly!

      --
      Current State: Pirates > Cowboys + Ninjas + Robots Yarrrr
    3. Re:pineapple? by Noaccess0 · · Score: 1

      Sorry, the closest they've come is with a suppository.

    4. Re:pineapple? by tsioc · · Score: 1

      guess I'm screwed then... atheist and darwinist to the core.

    5. Re:pineapple? by ChrisMaple · · Score: 1

      Yup, bromelain has been available from health food stores for decades.

      --
      Contribute to civilization: ari.aynrand.org/donate
  57. I fear the HIV-drug industry won't like this by davidwr · · Score: 0, Troll

    If someone finds a no-side-effect, affordable, treatment or vaccine for HIV, the drug companies that hope to make money off of HIV won't like it, and they'll take steps to delay it's entry into the marketplace.

    Thank goodness it's HIV we are talking about, the politics of HIV will limit how much of a delay industry can force without looking like the bad guys in the media.

    Another prediction:
    If this looks promising, a major drug company with an existing drug will invest enough money in the project to exert some kind of control. Those controls will include keeping the price high, at least at first, and scrupulously following FDA requirements to force delays.

    On the other hand, the best outcome may be that a drug company WITHOUT a stake in the game will invest heavily and use their influence to get this to market sooner rather than later.

    --
    Knowledge is how to play a game, intelligence is how to win, wisdom is knowing what game to play.
    1. Re:I fear the HIV-drug industry won't like this by juanfe · · Score: 1

      Well, that's why I think it's very meaningful that this research came not from big Pharma but from a University in Japan...

      More probability that people would have different motives for conducting the research. When you have a mechanism that is published in an academic journal, it may make it more difficult to obtain a patent on the mechanism itself, i'd suspect, rather than on the delivery vehicle.

      --
      ***Foucault is watching you..***
    2. Re:I fear the HIV-drug industry won't like this by rsynnott · · Score: 1

      It's an industry that's used to short-lived cash cows. It will cope.

      --
      Me (Blog)
  58. set pedant=1 by hedley · · Score: 1


    Work with the gist of the story. Its like the guy in CS class complaining the professor didn't put a semicolon on the blackboard pseudocode.

  59. But does it kill other cells too? by G4from128k · · Score: 1

    Safety is a real problem. Lots of things kill cancer cells or have other useful medical properties. The problem is that too many of them also screw up other cells or bodily processes. Rapidly dividing cells, such as those in the digestive system and hair follicles are often hosed by cancer drugs (hence the nausea and hairlessness of cancer treatment patients). I'd also worry that anything that accelerates immune function leaves the patient prone to autoimmune diseases. Sure, I'd rather not die of cancer, but if it means I get MS, rheumatoid arthritis, diabetes, hypothyroidism, etc., then I (and the FDA) might think twice about approving the drug or really calling it "a cure."

    Only about 1 in 5000 drugs gets approved (and I'd bet that all 4999 rejects started out promising). And only 1 in 3 approved drugs makes money for the company (i.e., is actually used to treat the number of patients that the company expected).

    I truly wish them the best of luck in finding new treatments for cancer, but I also recognize that the odds are stacked against the new drugs.

    --
    Two wrongs don't make a right, but three lefts do.
  60. Oh sure by A+nonymous+Coward · · Score: 5, Insightful

    And there's a cure for ebola, measles, smallpox ... abstinence from society. Total abstinence. That'll knock 'em dead.

    There's a cure for auto accidents, too, called the M1 Abrams tank. Mileage sucks, maintenance sucks, cost sucks, but by god, if we only let those people drive who could afford Abrams, why, we'd cut deaths from auto accidents down to almost zero.

    Or maybe you'd prefer banning automobiles altogether. Yeh, that'd stop auto accidents. Yeh.

    Get real. Expecting humans to abstain from sex except with their spouse is about as real as expecting people to stop speeding on the honor system. Especially when the number of people with AIDS in the US is around one million; one in 300. And with the incubation period being on the order of ten years, it sure isn't on people's minds all the time, especially when they get drunk or just plain feel good. Are you going to ban alcohol and feeling good too?

    It's real nice to spout platitudes about morality and abstinence being the only known cure, but it isn't a known cure because it doesn't stop transfusions or needle sharing spreading AIDs, and there are far more practical methods like using condoms. Are you part of the crowd that turns your nose up at recommending condoms to stop AIDs because it encourages amoral sex outside marriage? Must be nice to not have shit that stinks.

    Better to have a solution, condoms, which is widely used, even if it is only 95% effective, than some psuedo cure, alleged to be 100% effective, which is unusable in practice.

    Perfect is the enemy of good enough. Moral twerps have their heads up their asses.

    1. Re:Oh sure by Type-R · · Score: 2, Funny

      There's a cure for auto accidents, too, called the M1 Abrams tank. Mileage sucks, maintenance sucks, cost sucks, but by god, if we only let those people drive who could afford Abrams, why, we'd cut deaths from auto accidents down to almost zero.

      heh, until you run into the OTHER guys M1, then we're back to square one. :)

    2. Re:Oh sure by Ced_Ex · · Score: 3, Informative

      Just an FYI, there are cases being reported that the incubation period has dropped to just several months.

      Yikes!

      http://www.planetout.com/news/article.html?date=20 05/02/11/2

      --
      Live forever, or die trying.
    3. Re:Oh sure by Lifewish · · Score: 3, Insightful

      That sucks for those who contract it, but it's a good thing for the human race as a whole as these varieties are unlikely to survive very well - they'll kill all their hosts too quickly.

      Gotta love mathematics :(

      --
      For the love of God, please learn to spell "ridiculous"!!!
    4. Re:Oh sure by Anonymous Coward · · Score: 0

      First, I threw out abstinence as the best practice, but recognize safe sex if another method. Surely I don't expect people to stop living.

      I'm all in favor of condom for protection (both disease and pregnancy). Sorry if it didn't come across like that.

      it isn't a known cure because it doesn't stop transfusions or needle sharing spreading AIDs

      I do mention these as other ways of spreading. I don't have any statistics on it, but likely this number is small and would certainly be smaller if people practiced abstinence or safe sex.

      The reason I mention the simple solution is that I would prefer to see the money going to cure other issues that aren't behavior related. Certainly the various birth defects, alzhemier (sp?), etc... are better places to research as a behavior change won't solve them. If solving AIDs was the only problem, I could see spending money toward it, but when other issues exist, let's resolve them first.

      Oh, and on this comment, "Are you part of the crowd that turns your nose up at recommending condoms to stop AIDs because it encourages amoral sex outside marriage? Must be nice to not have shit that stinks.", I'd be the last one to preach about sex outside marriage. My son was actually about 1 year old when I married his mother. As for sex outside of a current marriage, yes, I don't recommend it, but that's my moral upbringing. For someone not married, they should abstain or use condoms. I'm sure the AIDs related infections (and other sexual diseases) would drop drastically.

      Are you saying having morals is a bad thing?

    5. Re:Oh sure by dabigpaybackski · · Score: 1

      Actually, the Abrams option isn't as bad as it seems. Just remove the 40-ton turret. Maintainance requirements are reduced, and you get a substantial boost to performance and gas mileage. This option is not without drawbacks, namely a lack of weaponry and turret crew to keep the driver company on long road trips.

      --
      "OH SHIT, THERE'S A HORSE IN THE HOSPITAL!"
    6. Re:Oh sure by Anonymous Coward · · Score: 0

      It's bad news for the human race because it says people are spreading it even though they know they're inflected. Hypersexuality at its worst.

    7. Re:Oh sure by rohan972 · · Score: 1

      Better to have a solution, condoms, which is widely used, even if it is only 95% effective, than some psuedo cure, alleged to be 100% effective, which is unusable in practice.

      Do you have an exaple of a country reducing the rate of AIDS by promoting condoms?

      Uganda recommends reduce casual sex and reduced HIV cases by 70%

    8. Re:Oh sure by ChrisMaple · · Score: 0, Flamebait

      OK, jerk. I won't be be getting AIDS because I won't be acting foolishly. You are free to be a sod and suffer the consequences. Reality, as always, will not be denied its due.

      --
      Contribute to civilization: ari.aynrand.org/donate
    9. Re:Oh sure by rwgeorge · · Score: 1

      "Gotta love mathematics :(" ... no I don't.

    10. Re:Oh sure by OhioJoe · · Score: 1

      All I know is that if men really ruled the world, tanks would be far easier to rent.

      -stolen from "If men ruled the world"

      OJ

      --
      "Artificial Intelligence usually beats real stupidity."
    11. Re:Oh sure by Flaming+Foobar · · Score: 1
      Do you have an exaple of a country reducing the rate of AIDS by promoting condoms?

      That's a stupid question. HIV never even spread to countries who have been promoting condom use as a precaution. In Scandinavian countries, for example, they talk about condom use in school starting at a very young age. All of them have a prevalence rate of 0.1 % or less. I couldn't find up to date statistics, but there were a total of 500 people with AIDS in Finland in 2003, for example. I'd love to see your prime example Uganda top that.

      --
      while true;do echo -e -n "\033[s\n\033[u\134_\033[B";done
    12. Re:Oh sure by Anonymous Coward · · Score: 0

      ... by god, if we only let those people drive who could afford Abrams, why, we'd cut deaths from auto accidents down to almost zero.

      Interestingly, people who investigate car crashes for a living call them "wrecks" or "crashes", but never "accidents".

      I think the Abrams approach would eliminate "accidents" entirely, but not wrecks...

    13. Re:Oh sure by rohan972 · · Score: 1

      That's a stupid question.

      No, it's a sensible question...

      In Scandinavian countries, for example, they talk about condom use in school starting at a very young age. All of them have a prevalence rate of 0.1 % or less.

      ...to which you gave a good answer (except for the unnecessary insult), thanks for giving the example I asked for, it's a good one, and worth knowing.

      The example of Uganda is a demonstration of an effective method of reducing HIV transmission in a country that already has a high level of infection. As far as I know, it has not been taught as morality, but hygiene. It is likely that many people in Uganda could not afford condoms. I agree that abstinence is not going to happen with the vast majority of people and is for the most part a waste of time to teach, but having a single partner is within many peoples capability and IS effective to prevent HIV.

  61. Can immune system beat cancer ? by Arioch_BDV · · Score: 1

    In Russia there is a serie of books by Mark Zholondz.

    About cancer, he tooks a number of biology books, counts forces of immune system, and even in ideal scenario, where immune system is not required to deal with diseases, poisons of outer environment, nor old and dead cells of our body - even then immune system would have enough soldiers to defeat only 33% of cancer cells. So there is another enti-cancer system in our bodies.

    Perdon my English.

    I wonder if some medical student with good knowledge of russian was interested to translate those broshures to English :-)

  62. Oh yeah.... by csharp_wannabe · · Score: 1

    Let the summer of love commence!

    --
    "C++ is to C as Lung Cancer is to Lung"
  63. Health supplements already available by Colin+Smith · · Score: 2, Interesting

    The supplement people advertise it as good for digestion rather than as a substance which helps fight cancer though.

    It's interesting how much scientific evidence there is now for the medical effects of what are basically just food supplements. I started looking into this stuff when my finger joints began aching after 10 years worth of typing for 8 hours a day. (Sorted BTW)

    e.g. The following all have scientific studies backing up the claims.

    Glucosamine and chondroitin helps fight arthiritis, there's animal research showing that they may also help with sports injuries to joints.

    Omega 3 oils significantly reduce the risk of heart attacks. They also help significantly with brain function; memory, concentration. They also help with joint suppleness and skin health. (Cod liver oil, fish oil, flax seed oil)

    St Johns Wort contains a mood enhancing compound which has a significant effect on minor depression. As effective as stuff like Prozac, with fewer side effects.

    Lycopene, from red fruit like tomatoes helps prevent prostate cancer.

    There's a load more. This isn't to say that all health foods/supplement claims are valid and if you have a problem you should see your doctor, but the saying "you are what you eat" certainly appears to be true.

    --
    Deleted
  64. I really dislike AIDS ignorance by Hachey · · Score: 1

    in Japan, Kumamoto University researchers have developed a drug that will block cells from the AIDS virus, thus making something akin to an AIDS vaccine.

    Ok, first of all, an *HIV* vaccine (AIDS is a syndrome, not a virus) is NOT akin to what they are talking about here. Although the article is woefully unsourced, the drug they are talking about is probably what they call a Fusion inhibitor. It basically keeps the virus particles on an HIV viron from interacting with the CCR5 receptor on the outside of a macrophage cell. Normally a HIV viron would be able to shut down the cells functioning by attaching to the CCR5 and thus gain an easy target to penetrate and infect.

    This drug class, while becoming more popular and good for those extremely drug resistant who are being treated with anti-retroviral meds, is not going to do anything but supress the virus a bit in it's current state in an already infected person. Once infected, you always have HIV. Fact. HIV has far to many ways to attack the body (cell-to-cell mediation, inducing an autoimmune response, etc). There is also no big trials mentioned. I'd like to know what stage theirs is in, but 40 people is NOT a big test group. It takes a much bigger one to test a drug, and even then, 'AIDS miricle drugs' don't have a great history (see AIDSVAX).

    Finally, an excellent article to read on everything HIV/AIDS is Wikipedia's AIDS article. Educate yourselves, please people. If I hear one more person afraid to pick up gum cause they think 'they'll get the AIDS', i'm gonna seriously wreck up the place.


    --
    Check out the Uncyclopedia.org :
    The only wiki source for politically incorrect non-information about things like Kitten Huffing and Pong! the Movie !

    --
    Please allow me to hate the creator of the 120-character limit: *HATES*. Thank you.
  65. Kumamoto University How appropriate by Anonymous Coward · · Score: 0

    in Swahili Kumamoto translates to Hot Pu**y
    Check for yourself.

    Kuma moto

  66. What a relief for me, too. by lheal · · Score: 1

    I thought I was going to have to get circumcised.

    --
    Raise your children as if you were teaching them to raise your grandchildren, because you are.
    1. Re:What a relief for me, too. by Internet_Communist · · Score: 1

      if you look around you'll find there's just as much evidence saying being uncircumcisied prevents aids as there is vice-versa. Most justifications of circumcision seem to follow that same format (different studies showing the opposite effects.)

      I've heard things like being circumcised means the pink inner-skin is exposed and that hiv/aids attaches to it more easily then the shaft skin and thus raises your chances, among other things.

      Ever since the late 19th century and the whole masturbation-scare doctors have been trying to justify the procedure, after it turns out masturbation isn't all that bad, they shift onto saying it'll prevent cancer, or aids, or urinary tract infections, etc, most of which aren't true or have no real significance. Of course they never really bring up the complications of circumcision in those studies, like loss of excess penile skin, reduced sensitivity (this happens no matter what,) loss of the glans, excess bleeding, blood infections, loss of entire penis, etc. And even though some of those may be rare, I'd make a bet that it's more common then it "causing aids" or what not.

      The fact is there is really not much medical justification for circumcision, that is why basically no pediatric societies recommend it. If only america would get a hint (though the rates here are steadily dropping.) It's become a social thing at this point, especially since some ignorant women thing it's "gross" not being cut. It just goes to show what happens when you condition people stupid.

      Let's not even mention the tribal african circumcisions which are quite grusome. This is a procedure which has to stop, unless medically necessary (which is pretty rare, usually only severe cases of balanitis xerotica obliterans would actually require it, steroid creams have reduced the need greatly in almost all other cases)

      --

      If you don't want someone to copy something, don't give it to anyone.
    2. Re:What a relief for me, too. by lheal · · Score: 1
      if you look around you'll find there's just as much evidence saying being uncircumcisied prevents aids as there is vice-versa.

      There is not. You just made that up, and you did it with poor grammar, besides. Applying "vice-versa" to your foregoing statement would result in "aids prevents being uncircumcised".

      Or, perhaps you have references other than, "I've heard things like ...."

      --
      Raise your children as if you were teaching them to raise your grandchildren, because you are.
    3. Re:What a relief for me, too. by Internet_Communist · · Score: 1

      Why would I make that up? I did read that. If what I read was incorrect then that's certainly not my fault, but I do have some sources if that will please you, sir grammar nazi.

      "Based on the studies published to date, recommending routine circumcision as a prophylactic measure to prevent HIV infection in Africa, or elsewhere, is scientifically unfounded." -International Journal of STDs and AIDS, 1999

      http://www.cirp.org/library/disease/HIV/vanhowe4 / is probably useful too. That's the actual journal..

      and might as well send the parent article:

      http://www.cirp.org/library/disease/HIV/

      --

      If you don't want someone to copy something, don't give it to anyone.
  67. Hello ... McFly ... Hello! by Luscious868 · · Score: 2, Insightful
    A cure for AIDs has existed for quite some time, it's called abstinence (probably not a difficult thing for most of the geeks here)

    From dictionary.com:

    Restoration of health; recovery from disease.

    Abstinence isn't a cure, abstinence is a form of prevention. If abstinence was a cure all you would have to do if you got AIDS is not have sex for a period of time.

    The only thing abstinence cures is a marriage. If neither partner has ever had sex before, especially with each other, then it's a shot in the dark as to weather or not they will have a healthy sex life once they are married. What if one loves sex and the other doesn't? What if one person thinks the other is horrible in the sack? The quickest route to divorce is a bad sex life. There's no way in hell I'd ever consider getting married before having sex with the women unless she was either rich (in which case if it didn't work, I'd get half her dough) or she was otherwise the perfect women in every way. Drop dead gorgeous, funny, smart, healthy, in good spirits almost 100% of the time, employed, energetic, willing to cook and clean if I handle the yard work, willing to be the primary caretaker if she wants children, willing to put up with all of my bullshit, willing to not complain that I spend "too much time with the guys", willing not to complain if she feels that "I never take her with me when I go out with the guys", willing to leave me along when I'm watching the game ... aka ... a women that doesn't exist.

    So in closing, you enjoy your abstinence and your either failed or unhappy marriange when you realize you don't click with your wife sexually, meanwhile I'll be chasing tail and really having a good time and when I finally do settle down and get married it'll either be a long and happy one or I'll come out of it rich.

    1. Re:Hello ... McFly ... Hello! by Anonymous Coward · · Score: 0

      You sure do like to "Go out with the guys"

    2. Re:Hello ... McFly ... Hello! by Ravatar · · Score: 3, Insightful

      The quickest route to divorce is a bad sex life. The quickest route to divorce is money-related issues.

    3. Re:Hello ... McFly ... Hello! by Anonymous Coward · · Score: 0

      Most common != quickest

    4. Re:Hello ... McFly ... Hello! by cheesybagel · · Score: 2, Insightful
      The quickest route to divorce is a bad sex life.

      Right. That must be why nearly noone used to get divorced at all when marriages were arranged and they only actually got to have sex *after* they were married.

      No, the basic reason for having divorce is when the couple loses patience. For a marriage to work, both need to concede on some things. People today do not wish to concede on anything, so marriages fail. Money usually being the problem.

    5. Re:Hello ... McFly ... Hello! by Rei · · Score: 1

      Yes. As we all know, the family that prays together suffers through a long, hellish marriage together.

      --
      "It felt almost as good as stealing cars from grandma." -- Margaret Thatcher, probably.
    6. Re:Hello ... McFly ... Hello! by JanneM · · Score: 1

      Right. That must be why nearly noone used to get divorced at all when marriages were arranged and they only actually got to have sex *after* they were married.

      You mean when everyone had premarital and extramarital sex as a matter of course, and men in power had (multiple) publicly acknowledged mistresses precisely because the marriages where arranged and loveless.

      --
      Trust the Computer. The Computer is your friend.
    7. Re:Hello ... McFly ... Hello! by tfoss · · Score: 1
      Right. That must be why nearly noone used to get divorced at all when marriages were arranged and they only actually got to have sex *after* they were married.

      Or perhaps it is that divorce is far more acceptable now than in those glorious bygone times of arranged marriage and socially accepted misogyny.

      -Ted

      --
      -=-=- Quantum physics - the dreams stuff are made of.
    8. Re:Hello ... McFly ... Hello! by OhioJoe · · Score: 1

      >The quickest route to divorce is a bad sex life.

      The quickest way to see if 'advice' is based on logic, or religion is to ask "Does it make sense?" Yes=logic No=religion. There is no logical reason to NOT live with your girlfriend/boyfriend and have sex before marriage. Religionists like to pretend to have logic "saving yourself shows devotion" or "having sex with someone other than your future spouse cheapens the sex you will have with your future spouse". Millions of happily married couples had sex before marriage, with each other and former boyfriends/girlfriends. And it's only cheapened if one of the partners THINKS it cheapened.

      OJ

      --
      "Artificial Intelligence usually beats real stupidity."
    9. Re:Hello ... McFly ... Hello! by OhioJoe · · Score: 1



      Right. That must be why nearly noone used to get divorced at all when marriages were arranged and they only actually got to have sex *after* they were married.

      You mean when everyone had premarital and extramarital sex as a matter of course, and men in power had (multiple) publicly acknowledged mistresses precisely because the marriages where arranged and loveless.


      Don't forget that divorces in those cultures/times are/were heavily shameful to have, if not dangerous. Religionists ignore that aspect as to why they were few and far between.

      --
      "Artificial Intelligence usually beats real stupidity."
    10. Re:Hello ... McFly ... Hello! by It'sYerMam · · Score: 1

      There is a perfectly logical reason to abstain before marriage, in order to preserve sex as something special. Whether or not you buy into that point of view is entirely a matter of opinion, but at least for some people, sex before marriage can really screw things up (NPI) especially if they end up marrying someone else.

      --
      im in ur .sig, writin ur memes.
    11. Re:Hello ... McFly ... Hello! by OhioJoe · · Score: 1

      Psycologically speaking, sex is sepcial with certain people, regardless of past experience. If you believe otherwise, than it won't be.

      OJ

      --
      "Artificial Intelligence usually beats real stupidity."
  68. hefeweizen by lheal · · Score: 1
    WTF is up with the pinapples slices in my hefeweizen.

    I don't think that's the method they used in the studies, but if it works for you, fine.

    And you must have a huge pair of hefeweizen.

    --
    Raise your children as if you were teaching them to raise your grandchildren, because you are.
  69. The real breakthru will come from Cambridge by WillAffleckUW · · Score: 1

    when a certain lab releases it's groundbreaking work on literally raising temperature inside human cells to destroy cancerous cells, while non-cancerous cells survive quite nicely.

    I was at a talk about this a month ago, and we're talking about 50 percent of all cancers.

    Now, as to how one delivers the temperature, that's actually not as hard as it sounds.

    You heard it here first.

    --
    -- Tigger warning: This post may contain tiggers! --
    1. Re:The real breakthru will come from Cambridge by cdn-programmer · · Score: 1

      Nuke em with a microwave?

      Gee, if so then if we get space based energy collection systems going where they beam the energy down as microwaves - then a stroll through the park might do it.

    2. Re:The real breakthru will come from Cambridge by Anonymous Coward · · Score: 0

      Nope. Fairly easy to do right now using
      far infrared heat (FIR). And, again, the
      alternative health community has known about this
      for close to two decades...

    3. Re:The real breakthru will come from Cambridge by Anonymous Coward · · Score: 0

      It can't be that groundbreaking when the SF novel "Half Past Human" by T.J.Bass, from the mid-1970s or so, has an episode where thousands of cancer patients in cryosuspension have the life support systems overridden to raise their body temperatures to fever temperatures.
      The idea being apparently that it raises the metabolic rate of the already overractive cancer cells to the point where they die of oxygen deficit or whatever...It was commented in the book that it was a historically well-known treatment for cancer. Complete with the disadvantage of a 20% death rate for a 30% cure. Kill or cure...

      So how is it "groundbreaking"?
      (though finding a way to raise overall body temperature while keeping the brain from being poached might be worth a try)

    4. Re:The real breakthru will come from Cambridge by Kartheris · · Score: 1

      I read an article about this somewhere. Something about microscopic golden spheres coated with a compound that causes it to latch of the cancerous cells. These are then injected into the suspected part of the body. Then they simply pass an infrared beam over your body to spot the bad cells and use a stronger beam to heat the temperature of the spheres and fry the cancer.

  70. Comment removed by account_deleted · · Score: 2, Informative

    Comment removed based on user account deletion

  71. Ouch by DrKyle · · Score: 2, Funny

    I don't know how popular those pineapple suppositories are going to be.....

  72. Re:Two women in China IMMUNE TO AIDS! by m00nun1t · · Score: 1

    There have been others immune found, and they are being studied. Been known about for many years, apparently started as an urban legend in the new york gay scene but was found to be true.

  73. Supplements by OverCode@work · · Score: 3, Interesting

    I'm going to go buy some of the pineapple extract (bromelain) tonight and start taking it daily.

    I have a bad case of melanoma (stage 4), and while there's still some hope in traditional treatments and clinical trials, I need every advantage I can get. If bromelain slows the growth of the tumors even a little, it's a huge help in combination with the other things I'm taking. And if it doesn't help, it probably won't do any harm. It's just natural pineapple extract, and it's been consumed for years.

    I'm taking artemisinin (sweet wormwood extract) for similar reasons, though I do have to be careful with my dose of that because it's somewhat hard on the liver. I'm also waiting for an order of Vitamin B17 (amygdalin/laetrile) to arrive. The latter was somewhat hard to track down because of a stink the FDA raised about it a few years ago.

    Dietary supplements alone won't cure me, but they just might help, and as such it would be ridiculous for me not to try them.

    -John

    1. Re:Supplements by Overdrive_SS · · Score: 1

      Good luck with the B17, I've heard of a few people having a lot of success with it.

    2. Re:Supplements by Anonymous Coward · · Score: 0

      Well, be careful with that pineapple extract; it's fatal in large dosages.

      Not, of course, that you aren't facing that possibility at present.

    3. Re:Supplements by bill_mcgonigle · · Score: 1

      The latter was somewhat hard to track down because of a stink the FDA raised about it a few years ago.

      You still can't buy tryptophan because there was a contaminated batch made by one manufacturer in 1989 and the FDA saw it as an excuse to ban it.

      Before that it was becoming very popular as a safe, effective sleep aid. One wonders if Advil or Coumadin would be banned by the FDA if there were a bad batch produced.

      If you have any question as to whether the FDA is in the pockets of Big Pharma you don't have to look much further.

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
    4. Re:Supplements by OverCode@work · · Score: 1

      Coumadin, as in warfarin sodium, the powerful blood thinner? That's big pharma, I believe. I doubt they'd axe it.

      And there's a lot of money behind Advil, as well as public loyalty. Banning it would cause a serious fallout.

      I don't know about trytophan, but I use melatonin when I need a sleep aid, and it works very well.

      -John

  74. Re:C'mon folks, get real (yes please!) by Biodecoder · · Score: 2, Insightful

    As a biomedical scientist working in the field of HIV and immunology research in the past 15 years (having published over 40 papers in journals like Nature, Science) I fully and completely agree with Yeasbeast's comment. Where are the peer reviewed papers on these "major breakthroughs"?? If there was really a true breakthrough in either HIV or cancer research it would make it headline in Nature, Science or Cell, sorry to say /. headline only enhances these pure BS hype, because most don't quite understand the nature of biological research and discovery.

  75. Re:haha you fail it by Anonymous Coward · · Score: 0


    Happy Friday!

  76. Re:Two women in China IMMUNE TO AIDS! by Tony+Hoyle · · Score: 1

    There's a town in northern italy where a significant number of people are now immune... the immunity is a great chat-up line :)

    Evolution in action!

  77. No by A+nonymous+Coward · · Score: 0, Flamebait

    I apologize for reading your post as a neocon rant. The Bushie crowd loves to spout about abstinence, and that is the first thing that comes to mind when someone mentions it.

    As for morals, no, everyone has morals. My rant was about the holier than thou moralists who deny everyone else having morals that bugs me. It's bad enough that they are so smug as to assume they, and only they, know the One True Path, but when you peek behind the curtain, they all seems to have been practicing the opposite of what they preach. Then put them in charge of the Bushie's plan for fighting AIDs, and it only means that they will have no effect whatsoever on stopping AIDs.

    Again, mea cupla on misreading your post as a rant from one of those holy hyprocrits.

    1. Re:No by superyanthrax · · Score: 1

      They are not exactly neocons. Neocons are the people who want to abandon the traditional conservative stance of isolationism. Old-school Republicans would have opposed the war in Iraq/Afghanistan. Note World War I, and the isolationist sentiment before WW2. Both were generated by the Republicans. Neocons like Cheney and Rumsfeld turn that on its head and say, yes we should intervene in other places. Hence, we have the "war on terror". The neocons don't particularly care about social issues. What you're referring to are the Christian fundamentalists, like Jerry Falwell and Pat Robertson. They are the ones who believe the Bible is God's word, we should have prayer in schools, etc. They also claim that abstinence is the only foolproof cure to STD's, which is technically true, but they ignore the fact that abstinence is almost possible to realize. They care a lot about domestic social policy, but not foreign policy. Bush happens to be in both categories, however, as we can see by his fundamentalist leanings and his neocon advisors (Cheney/Rumsfeld).

    2. Re:No by Anonymous Coward · · Score: 0

      Actually I support Bush but I'm more in the middle than to the right. I probably should have posted something slightly longer on my first post to keep from being misinterpreted. I do think people over simplify both the democratic and republican parties though. People can support the general goals of a politician and be reasonable. (FYI - I'm a republican, I'm Catholic, and a very moderate conservative - yes, we do exist).

  78. For the metal fans.... by Prod_Deity · · Score: 1


    She let me taste that sugar whole and I wanted more

    Great concept, pineapple juice.

  79. Re:Yes but... by Anonymous Coward · · Score: 0

    ...NOBODY expects the Spanish Inquisition!

  80. Re:DDT Cheap shot by Captain+Sarcastic · · Score: 1

    Hey hippies---are you happy you got DDT banned now? All those dead Africans say thank you!

    Got news for you - it isn't banned. Check http://en.wikipedia.org/wiki/DDTwikipedia, and you'll find that it is definitely in use in Africa, and other tropical areas "where mosquito-borne malaria and typhus are greater health problems than DDT's potential toxicity."

    Try checking your facts before you start calling names, would you?

    --
    Strike while the irony is hot! -- The Freethinker
  81. Time to sell Dell stock! by MCTFB · · Score: 1

    And start buying Dole stock!

    1. Re:Time to sell Dell stock! by Anonymous Coward · · Score: 0

      Bob Dole thinks that investing in Dole stock is a great idea. Yes, he does.

  82. Re:Two women in China IMMUNE TO AIDS! by SubconsciousSeraphim · · Score: 3, Interesting

    I know this may be sort of thick of me, but does immunity also imply that you won't carry it?

  83. There's some legitimacy here by bshroyer · · Score: 1

    I've been following for some time an oncolytic (viral) treatment that targets the RAS pathway, which is referenced in this article. The human reovirus targets cells with a disrupted RAS pathway, infecting and killing them.

    Some great pictures can be seen here

    The "CCZ molecule", states the article, "blocks a protein called Ras, which is defective in 30 percent of all cancers."

    So there's a little bit of precedent, here.

    --
    The cure for cancer is coming: Reovirus
  84. The world is riding on American healthcare! by Cryofan · · Score: 0

    THe healthcare prices that Americans pay carry all the rest of the world when it comes to medical research! THat is why our American drug prices are so high, why our American healthcare costs so much!

    isn't that what the rightwingers say whenever they encounter arguments that the other countries pay much less in healthcare?

    Yeah....and where was cloning first accomplished?

    Yeah....uh huh....we Americans are carrying the rest of the world when it comes to medical research. Sure....

    --
    eat shiat and bark at the moon
    1. Re:The world is riding on American healthcare! by rsynnott · · Score: 1

      No, American drug prices are high because you have a "free market" that is anything but. I never even realised that that's the excuse you were given by your government; it's nonsense. Many drugs are developed in the US, many in Europe, many in Asia.

      --
      Me (Blog)
    2. Re:The world is riding on American healthcare! by ChrisMaple · · Score: 1

      Many countries threaten to invalidate the patents for drugs held by US companies unless the companies sell the drugs at slightly above incremental cost. These countries - that's you, Canada, Germany, France, et. al. - are engaging in extortion.

      --
      Contribute to civilization: ari.aynrand.org/donate
    3. Re:The world is riding on American healthcare! by rsynnott · · Score: 1

      Or, taking a little money away from the shareholder, who now tragicly won't be able to buy a new Merc this season, to prevent people from DYING. A sufficiently unjust law is no law at all (tho most non-generic drugs are sold with considerable profit in Europe anyway, you know; just not as much profit.)

      --
      Me (Blog)
  85. Re:Two women in China IMMUNE TO AIDS! by Elwood+P+Dowd · · Score: 2, Informative

    Back when they were first discovered (1990s), these symptomless carriers seemed like they could have been the genesis of a separate species. Children that they had with other symptomless carriers would have HIV and only be able to have survivable offspring with other symptomless carriers. Given time we'd have separate gene pools.

    Around 2000 or so, they figured out how HIV- children could be born to HIV+ mothers. So there won't be any separation of the gene pool. Due to sexual recombination, if there are no disadvantages to this adaptation (like sickle cell anemia), then the gene may quickly spread throughout the species. Quickly meaning hundreds of thousands of years rather than hundreds of millions.

    --

    There are no trails. There are no trees out here.
  86. Hate to burst your bubble by Anonymous Coward · · Score: 0

    Hate to burst your bubble, but "News for CS Nerds" implies that the most of the people here have taken CS Theory classes, and have a rudimentary understanding of discrete mathematics/linear algebra.

    Mostly it's uninformed quips.

    Don't even get me started on hardware stories on slashdot, most people here have no idea how a transistor even works.

  87. You don't know what a homeopathic medicine is by Anonymous Coward · · Score: 0

    Most people don't.

    "Homepathic" does not mean that it's natural, herbal, or any of this.

    Homeopathic means that the medicine is expected to do its work through sympathetic vibrations.

    One of the odd things about this idea is that supposedly, the less of the active ingredient there is, the more intense the vibrations, and the more effective the "medicine".

    The result is that the most intense, most "powerful" homepathic medicines are literally nothing but water in a bottle.

    Homeopathy is one of these 19th century quackery ideas that's been inherited by future generations without an awareness of the original form of the idea. A modern populace would never swallow the idea if they actually had to have it explained to them, because even ignorant people know just enough to think making something more dilute is not going to make it more effective.

    People only believe in homeopathy because the word's been around for a while. Similarly, hypnosis clearly has a psychological effect, but the original version held that a hypnotized retard could outthink all the geniuses of history, and that by touching a tree, could charge the tree with animal magnetism that would hypnotize other people....

    What it comes down to is that placebos work. They always have worked. They will continue to work. There are just some things that work better.

  88. Re:Two women in China IMMUNE TO AIDS! by Anonymous Coward · · Score: 0

    Note that quite large portions of the northern european population have increased HIV resistance (not total immunity, but enough that even with pandemic HIV it's likely sufficient europeans would survive past breeding age to keep european civilisation going) as various mutations that likely helped people survive one or more of the various plagues that swept through europe (e.g. smallpox, and The plague) also help prevent HIV entry into cells.

    People don't generally make a song and dance over it because it lends fuel to the "AIDS is a western plot to cripple africa" meme, but google "CCR5 mutation" (note that several links will be disinformation).

    Analyses have shown that the CCR5-D32 mutation spread through the european population extremely quickly 700-800 years ago as various horrible diseases swept through and the population crashed. People who think humans have stopped evolving or that evolution happens slowly are very much mistaken.

  89. some Mushrooms have strong anti-cancer properties by cdn-programmer · · Score: 1

    Specifically Lentinula Edodes (Shitaki), some Pleurotus species including P. Ostreatus (oyster), Grifola frondosa (which has strong anti HIV properties as well), Hericium erinaceous and many others have been shown to have medicinal properties including anti cancer - anti-tumour, and anti-colesterol. Not all species are effective for all ailments of course. Some of these mushrooms are available in the supermarket.

    If you cannot buy them it is feasible to grow them... They make nice pets. They don't bark - they don't bite people - you don't need to take them for a walk and you sure don't need to clean up after them. Also - they only need to be fed once.

    There is good information on the net and seminars are available.

  90. Sadly, by empaler · · Score: 1

    I knew someone great who had had AIDS for twenty years without ever getting medication for it, who died of cancer three months ago.

    To top it off, he died because the doctors didn't believe that he had a growing lump in his neck. They said they didn't have the funding to check such arbitrary nonsense (we have public health insurance in Denmark).

  91. Lack of money wouldn't solve much by Anonymous Coward · · Score: 0

    Cures for a lot of diseases probably already exist but there is no money in curering people, just treating their symptoms. You really think drug companies care about your health?

    That's true, but you can't blame only the drug companies. The information is out there for how to cure things but almost nobody cares to look. I'm not talking about crackpot theories but successful treatments from serious scientists.

  92. Call me a moralist but... by Anonymous Coward · · Score: 0

    ... I don't get WTF is up with people who think sex outside of marriage is okay? I mean shit, just live with her if you can't commit. I'm not referring to those people who get drunk or do something stupid and end up cheating, but specifically to the crowd that thinks it's okay to get married and have sex with other people. It isn't really about morality either, it's about logic. What fscking point is there to getting married if you want to have sex with other people? Just to be able to say you're married?

    More on topic, while I agree with the use of condoms, I think you put down abstinence a little too harshly. It's 2005 and guess what? Cold showers still work! No shit! So does spanking the monkey! Whoduh thunk it? STDs are a high price to pay for having fun with some skank, and as you pointed out, Condoms aren't perfect.

    My main point is, people would serve their own best interests better using a little more self control. Stop having sex? No, but Jesus, use some fscking discretion. Be careful where you stick it(and for the ladies, be careful who you let stick/lick you). Testing for STDs is available and no decent person on the planet would object to that. It's not a matter of morality, it's a matter of self preservation.

    1. Re:Call me a moralist but... by Dwonis · · Score: 2, Insightful
      It's not a matter of morality, it's a matter of self preservation.

      Precisely. Ever notice how some sort of marriage ceremony seems to be engrained in many otherwise distinct cultures? It leads me to suspect that what people like to call "sexual morality" is really just a survival trait that evolved as a result of natural selection. Recent research on sexual networks (example) seems to point to the same conclusion.

    2. Re:Call me a moralist but... by Domo-Sun · · Score: 1

      It's not a matter of morality, it's a matter of self preservation. ...marriage ceremony seems to be engrained in many otherwise distinct cultures?..."sexual morality" is really just a survival trait that evolved as a result of natural selection.

      I agree with you, however, promiscuity, unfaithfulness and even rape may also increase fecundity, creating a mating advantage, to some extent. So sexual "immorality" may also be a trait that evolved from natural selection.

  93. Cures are money by TiggertheMad · · Score: 1

    So individual choices might have more of an effect than you think. I remember an interview with an industry exec where he explained that his children (I think) had cystic fibrosis, and that gave him perspective that inspired him to push for new and better drugs.

    People keep cynically pointing out that you can make more money by simply treating symptoms rather than curing a disease, but that is a simplistic model that doesn't take into account a free market.

    Suppose you make AIDS maintenance medications that keep people alive. Your lead researcher comes to you and says that he has discovered a medication that may cure AIDS completely. Do you research it? Hell yes, because if you don't your competition eventually will. And while the market might dry up for AIDS treatment, there is money to be made in the cure. Anyone who doesn't keep up with the market WILL wither and die. Just look at what happened to buggy makers, or what is currently happening with the **AA companies.

    --

    HA! I just wasted some of your bandwidth with a frivolous sig!
  94. HIV immunity has already been documented before. by spineboy · · Score: 2, Insightful
    THe HIV virus relies on a cell receptor molecule CCR-5 (cell chemokine receptor -5) that enables the virus entry into the white cell (CD-4 T cells to be precise). Certain people have a variant , or are defficient in that cell surface receptor, so that the HIV virus has nothing to "Grab" onto, and thus does not infect the person.

    Curent HIV vaccines rely on the fact that people seem to suffer no ill effects of not having this receptor and are currently a main focus of vaccine research.

    --
    ..........FULL STOP.
  95. Re:Two women in China IMMUNE TO AIDS! by scrub76 · · Score: 1
    There is a huge amount of research into those individuals do not become infected after repeated HIV exposures or who appear only transiently infected. Some are resistant because of an unusual CCR5 mutation (the virus uses CCR5 to enter cells...esp. right after transmission), but we don't know why others are resistant. A tragic aside -- in the late 90's, there were several studies of prostitutes in Kenya who did not become HIV+ despite huge numbers of exposures. Some then took a break from prostitution, headed back to their rural homes, etc. but eventually wound up prostituting themselves again. After the break, several became HIV+, showing how tenuous "protection" can be (see here.

    A much bigger story this week is the striking result of a clinical trial of male circumcision. Apparently circumcised men have a 70% lower risk of contracting HIV than uncircumcised men (see here). Though others have shown this anecdotally, proof in a large clinical trial could revolutionize HIV prevention -- particularly in sub-Saharan countries where HIV incidence is high and male circumcision is currently rare.

  96. Note of caution by IdahoEv · · Score: 1
    Dietary supplements alone won't cure me, but they just might help, and as such it would be ridiculous for me not to try them.


    A word of caution: anything one puts in one's body can conceivably be either beneficial or detrimental. People have far too strong a tendency to believe that anything plant-based or "natural" cannot harm them.

    You in particular sound like you've done your homework on the things you're taking, but I get nervous at the hordes of people who fill themselves with many plant-based drugs thinking they have nowhere to go but up.

    Good luck with your struggle with melanoma; that's a rough lot.
    --
    I stole this sig from someone cleverer than me.
  97. Why don't you begin with it? by bufalo_1973 · · Score: 1

    Don't think "how good it would be", just open a site like /. and put bioresearch news, use RSS, tell everybody you opened this site, ... Maybe it's interesting enought to become an important site (I hope so).

  98. Naturally occuring != homeopathic by bill_mcgonigle · · Score: 1

    Naturally occuring != homeopathic

    You're quite right about tumeric, etc, but they're effective in strong doses.

    To make a homeopathic preparation of tumeric you put a drop of tumeric solution in a swimming pool full of water. Then you let it dissolve, and take ten drops from that swimming pool and put it ten other swimming pools full of water. Then you bottle the water from those ten swimming pools and sell it as 'homeopathic medicine'.

    If you believe (as in blind faith) in this technique, by diluting the molecules you're imparting the cosmic energy of tumeric onto the water and it's amplified by the dilution. You'll have trouble finding good studies on this in PubMed.

    The best part is, thanks to the hydrological cycle, every drop of water on earth is, by now, a preparation of every kind of homeopathic medicine known to man.

    So, grab a glass of tap water and slug it back. It's at least known to cure dehydration.

    --
    My God, it's Full of Source!
    OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
  99. AZT? by Anonymous Coward · · Score: 0

    They do certainly shed some doubt on the treatment of aids.. with drugs such as AZT. None of the articles that counter the aliveandwell stance focus on the history of AZT. They rather just talk about how HIV causes AIDS... and even in that fail to tackle the faults that AliveAndWell point out in the correlation of HIV and AIDS. There is no causation... and limited correlation between the two afflictions. I'm not saying Alive and well is right... It's just there is insignificant evidence to fight for either side of the spectrum.

  100. sexual behavior by falconwolf · · Score: 1

    The reason I mention the simple solution is that I would prefer to see the money going to cure other issues that aren't behavior related. Certainly the various birth defects, alzhemier (sp?), etc... are better places to research as a behavior change won't solve them. I

    Sure those birth defects are related to sexual behavior, if sex weren't involved then those births wouldn't happen more than likely. I've only heard of one case where a lady got pregnant without having sex, and that was during the US Civil War when a man got shot in the balls and the shot passed through and hit a lady, she ended up pregnant.

    Falcon
    1. Re:sexual behavior by Anonymous Coward · · Score: 0

      if sex weren't involved then those births wouldn't happen

      True that birth defects would happen without sex (except in extreme cases as you described), but often, the birth defects can not be detected (at least by current methods) until after the baby is conceived. There are of course some exceptions but how many healthy parents end up having children with problems? My wife and I both are healthy (nothing worth noting medically other than glasses for better vision) but I have a son with ADD and a daughter with asthma. I'm not sure of a way to know in advance that either would have these to deal with. The point I was making is where would you rather see money spent, on something that can be changed by behavior or something that requires research? With limited resources, I know where I'd put my money.

  101. hemp, er marijuana by falconwolf · · Score: 1

    Imagine the peace the world would have if they would do that and legalize marijuana... for medicinal purposes of course

    Legalize hemp altogether! The only reason it was made illegal via the Marijuana Tax Act in 1937 was because it posed a threat to some wealthy and powerful individuals. But even during WWII the governmemt encouraged farmers to grow hemp, making the movie Hemp For Victory to show them. Hemp is one of most if not the most industrially versatile plants there is. Hemp can be used to make things from cloths to rope to vehicles and can power the vehicle even. Rudolph Diesel designed his diesel engine to run on vegetable oil including oil made from hemp. Henry Ford, on his Iron Mountain Estate built a car that used plastic made from hemp and was powered by methanol he made from hemp. Thomas Jefferson wrote the first and second draft of the Declaration of Independence on Dutch Hemp paper.

    Falcon
  102. Re:Two women in China IMMUNE TO AIDS! by falconwolf · · Score: 1

    According to this story [chinadaily.com.cn] (previously reported on slashdot), two women in China were found to be immune to AIDS. Why don't we just study what's different about these two chicks and mimick that!?!?! We already have the human genome mapped out, it can't be that hard for the proper gene therapists to replicate.

    Actually there is some research going on like this. Some prostitues in Africa, Nairobi, Kenya , were found to have an immunity to aids so a vaccine was developed and was being tested. This story is almost 4 years old so I don't know if anything came from it.

    Falcon
  103. AIDS and prostitutes in Kenya by falconwolf · · Score: 1

    A tragic aside -- in the late 90's, there were several studies of prostitutes in Kenya who did not become HIV+ despite huge numbers of exposures. Some then took a break from prostitution, headed back to their rural homes, etc. but eventually wound up prostituting themselves again. After the break, several became HIV+, showing how tenuous "protection" can be (see here [jci.org].

    CNN has an article on these, The search for an AIDS vaccine, 20 years on

    Falcon
  104. pineapple in beer by falconwolf · · Score: 1

    I guess it's going to be a long weekend of explaing WTF is up with the pinapples slices in my hefeweizen.

    If you brew maybe you can do what I think I'll try, adding some pinapple to your mash. I like how the Dutch brew using different fruits like strawberries and such and have wanted to try it myself. Now I've got a good reason to try pineapple.

    Heading off to the Brew Shop

    Falcon
  105. barley beer by falconwolf · · Score: 1

    hefeveizen, to my knowledge, is a very yummy wheat beer (as opposed to barley).

    I prefer a good red beer made with crystal barley, especially if I brew it, though it's been too long since I had a good weisenbeir (sic).

    Falcon
  106. Dude, you forgot the umlaut. by falconwolf · · Score: 1

    How many Americans know how to type special characters on an American keyboard? I know I don't recall how so I ended up finding a webpage that tells how then saved it. I think I'll be finding it even harder next year as I hope to be taking a class in Portugese. Then again maybe with practice I'll get better.

    Falcon
  107. lol by Morpherex · · Score: 1

    Oh great, does this mean Gays can fuck eachother and not worry about AIDS?