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Brazil Breaks Patent to Make AIDS Drug

Andy Tai writes: "In this CNN story, Brazil decides to break a patent over an AIDS drug for public benefits. Brazil will produce the drug domestically without agreements with patent holder, the Swiss pharmaceutical company Roche. Brazil's efforts to fight AIDS have been praised internationally, and it successfully prevented the US Government from bringing complaints in the WTO on behalf of the drugs industry. This may set an important example that public needs justify the disregard of patent protection." There's another article in the Boston Globe about the decision.

1,041 comments

  1. Way to fucking GO!! by pompomtom · · Score: 2, Insightful

    There's a time and a place for all this profit-minded patent shite.

    AIDS ain't it!

    --

    Buckets,

    pompomtom

    "There's an exception to every rule. Except for some rules"
    1. Re:Way to fucking GO!! by Bonker · · Score: 2

      I'll say amen to that.

      It's funny how having world-threatening plagues will put your priorities in order, innit?

      I hope everyone looks at this and makes the connection:

      Patents == People Dying of AIDS

      --
      The next Slashdot story will be ready soon, but subscribers can beat the rush and slashdot the links early!
    2. Re:Way to fucking GO!! by codeforprofit2 · · Score: 1

      "Patents == People Dying of AIDS"

      No, patents == Possibility to put down billions in research and development to fight the decease.

    3. Re:Way to fucking GO!! by BoyPlankton · · Score: 1

      It's a shame that without 'profit-minded patent shite' there's no incentive for companies to develop the drugs in the first place.

    4. Re:Way to fucking GO!! by revscat · · Score: 2

      Y'know, people might actually take you seriously if you could at least spell simple words like "disease."

    5. Re:Way to fucking GO!! by Drakantus · · Score: 1

      Yeah thats just too bad, poor companies. Instead we will be getting all the advances from public money at univerisities. Ask me if I care.

      --
      I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    6. Re:Way to fucking GO!! by ROBOKATZ · · Score: 2
      Yeah right. A $10,000 grant is gonna pay to develop and drug and bring it to market from the ground up.


      Maybe you'll care when you're on your death bed from an unknown side effect of a poorly researched drug, or dying from a disease that has a cure but because the funding to study it for approval is not available, nobody makes it.

    7. Re:Way to fucking GO!! by Nos. · · Score: 1

      I thought he missed a "d" as in "deceased". I guess he's thinking the "Living Dead Movies" were about the unfortunate people that died of AIDS/HIV and are now rising from their graves wanting brains!

    8. Re:Way to fucking GO!! by Lardmonster · · Score: 2, Interesting

      Absolutely - we're talking about people's lives here.

      These pharmaceutical companies are turning over _billions_ every year, making bucketloads of cash out of other people's misery.

      Now, I don't deny them their profits; sure, the only way to keep making scientific (medical) advances is though continuous investment...

      I guess that's what happends when businessmen (and women) run businesses rather than the scientists and the engineers.

      It's all a trade-off; if Roche (and its contemporaries) were run by scientists for the benefit of ordinary folks, then they'd be in administration (Chapter 11 for you US folks) within weeks :-(

      matthew

      --
      The more advanced the technology, the more open it is to primitive attack
    9. Re:Way to fucking GO!! by update() · · Score: 2
      There's a time and a place for all this profit-minded patent shite. AIDS ain't it!

      In my time in science, I've learned that whenever people tell you how important it is what you're doing, it invariably means your life is about to be made worse. No one ever seems to say, "This is important! You deserve more money (benefits, whatever..)."

      There's an odd sort of market theory here where it's perfectly acceptable to earn hundreds of millions of dollars because you can hit a curveball or you IPO your worthless Internet startup just the right week, but if you can save lives -- well, that's just too darned important for you to be allowed to make money from it.

      As it happens, I think the pharmaceutical companies involved here are being ethically callous and idiotically short-sighted from a PR point of view. But I can't help noticing that the people who are so eager to take from them because, gosh, it's just so imeportant! don't ever seem to consider dropping some of their own money to make sure that drugs are readily available.

      Honestly, if you had told Act-Up! protestors in the early '90s that in 2001 the biggest villain in the AIDS world would be the companies that cure it, they wouldn't have believed it. Hey, make A-Rod play for free and use his money to fight AIDS.

    10. Re:Way to fucking GO!! by radja · · Score: 2

      >I guess he's thinking the "Living Dead Movies" were about the unfortunate people that died of AIDS/HIV and are now rising from their graves wanting brains!

      It was a way to get to the victim's intellectual property, which is obviously stored in their brains! It's all a conspiracy to void the patents of good american capitalist pharmaceutic companies!

      //rdj

      --

      No one can understand the truth until he drinks of coffee's frothy goodness.
      --Sheikh Abd-Al-Kadir, 1587
    11. Re:Way to fucking GO!! by Bobo+the+Space+Chimp · · Score: 1

      Rember the golden rule of government power-hungry politicians: One person saved by stealing the efforts of others in inventing drugs is worth millions dead in future years because of delays in research as drug companies don't invest as much because their profits are immediately eviscerated.

      But it's funny how this mass-murdering "horizon effect" is completely ignored in place of silly pandering to the masses, innit?

      --
      I am for the complete Trantorization of Earth.
    12. Re:Way to fucking GO!! by codeforprofit2 · · Score: 1

      English is not my native language, is that a crime?

    13. Re:Way to fucking GO!! by Tackhead · · Score: 2
      > > "Patents == People Dying of AIDS"
      >
      > No, patents == Possibility to put down billions in research and development to fight the decease.

      Let's get it right, once and for all:

      Patients == People Dying of AIDS.
      Patents == Temporary, legally-granted, monopolies on production of drugs to fight the disease.

      As for the "decease", personally, I have nothing against the decease[d], other than that they keep writing letters in favor of Microsoft's not-so-temporary, and very much not-legal, monopoly. But that's the last Slashdot story and doesn't have much to do with AIDS.

      Everybody clear now?

    14. Re:Way to fucking GO!! by Bobo+the+Space+Chimp · · Score: 2, Informative

      So the intellectual elite are just another servent demanded to kneel to the "public" benefit?

      A company that cured AIDS tomorrow and started charging $10,000 per cure would do more to save lives than all the research that preceeded it, and more than all the loud-mouthed technocrats could do.

      I am reminded of Florida's last major hurricane, where people in northern FL, Georgia, whatever, would load up trucks of ice bags and go into the devastated areas and sell them for $10.00 per bag.

      "Why, how horrible!" So it was outlawed.

      And soon, no one was getting any ice at all for love or money.

      Thanks, government, for the "help".

      --
      I am for the complete Trantorization of Earth.
    15. Re:Way to fucking GO!! by Bobo+the+Space+Chimp · · Score: 5, Insightful

      > These pharmaceutical companies are turning over
      > _billions_ every year, making bucketloads of cash
      > out of other people's misery.

      Making bucketloads of cash ENDING other people's misery, which is more than you, or Hillary, or others are doing.

      Funny how greedily searching for solutions to others' miseries, miseries that those suffering pray for a solution to, solves those problems all the while people stand on rocks pontificating how evil that process is. Yet when you look in their socialist bag, you don't see too much at all.

      --
      I am for the complete Trantorization of Earth.
    16. Re:Way to fucking GO!! by cpt+kangarooski · · Score: 2

      Of course, without people who can afford the drugs, or who are dead because they didn't have
      the drug, there is ALSO no incentive.

      Neither absolutist position - a total lack of patents, nor a uniform existance of patents is
      viable. There's a middle ground within which the best interests of the people (to whom the
      government is beholden always) may be served. If Brazil is only doing this where the lives
      of their people are very much at stake, I applaud it.

      Yes, without patents it is unlikely (but not certain!) that the research would be performed.
      (I rather think that there is still enough money to be made that it would be, in the same
      manner that there are computer manufacturers at every niche of profit margin from pennies
      per system on up) And this would be harmful, because there might be no medicine at all. But
      people's lives are also at stake, and it is a very difficult position to defend letting
      people die for financial gain.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    17. Re:Way to fucking GO!! by BoyPlankton · · Score: 1
      What's your plan? Kidnap researchers and force them to develop the drugs for humanitarian purposes?


      The problem here isn't Roche ... it's the Brazilian government. One of those articles discussed how Roche is bending over backwards trying to meet their demands. There's something else going on that's pressuring Brazil to do this. Probably somebody seeking re-election or something.

    18. Re:Way to fucking GO!! by Lardmonster · · Score: 1

      > Making bucketloads of cash ENDING other people's misery

      true - but only in a small number of cases. Even here in the UK there have been a number of high-profile decisions whereby the National Health Service has decided not to provide life-saving (or dignity-gaining) treatments purely because of cost.

      And the UK is supposed to be a developed country - in the top 20 worldwide. OK, so I'm in no position to blame the NHS itself - they do a fine job, considering.

      But we are in danger of having a society there people are second-class citizens simply because of their geographic location and the GDP of their country. The right to a decent quality life is fundamental. I'm not against people paying for medical treatment, but I do object to people paying for life-saving treatment.

      You've got to understand that the Brazilians who took this decision are desperate. Take South Africa as an example: they got to a stage where 10% of the population was HIV+ and over 100,000 people died from AIDS-related illnesses last year. South Africa took on the drugs-manufacturers in April and won - and I applaud Brazil for trying to do the same.

      If Roche cut the cost of their drugs to a quarter I bet they'd still be in profit - considering all the extra penetration they'd get into markets of the developing world...

      --
      The more advanced the technology, the more open it is to primitive attack
    19. Re:Way to fucking GO!! by lobsterGun · · Score: 1

      Thats not all they did in Florida. They also tightened licencing restrictions on capenters, electricians, plummers etc. so that if you had a damaged house you would have to go through one of the local contractors and not use imported craftsmen.

      It was great for the local craftsmen, they made a ton of money off that hurricane....but if you were a homeowner you really got the shaft.

    20. Re:Way to fucking GO!! by Drakantus · · Score: 1

      The transport of bags of ice is actually a service. "allowing" the use of IP is not.

      --
      I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    21. Re:Way to fucking GO!! by Drakantus · · Score: 1

      Roche is relying on artificial IP laws. Laws which are meaningless in reality, only usefull in the context they are in. In the same way that US currency is worthless without the common agreements that it has an artificial value. Just as US currency is worthless when there is nothing to buy, the IP is worthless if the customer's can't afford to pay for it's use.

      --
      I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    22. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      That's right.

      Information 'wants' to be free, huh?

      Nobody who does creative work provides a good and deserves compensation for it.

      Clear thinking, dude.

    23. Re:Way to fucking GO!! by mimbleton · · Score: 1

      "Roche is relying on artificial IP laws. "

      Dude, without these laws there won't be Roche or their drugs.

    24. Re:Way to fucking GO!! by number+one+duck · · Score: 1

      Just damn lucky those zombies don't have sex with anything though...

    25. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      Yes, without patents it is unlikely (but not certain!) that the research would be performed.

      I'd say it would be very much certain to be none. After all, if there was a company that did all the R&D, testing, screening and all I had to do was hire my own chemists to copy the formula, I'd be there in a sec.

    26. Re:Way to fucking GO!! by cpt+kangarooski · · Score: 1

      Uh huh. You're assuming that all chemicals are equally easy to make, when in fact there may be a process involved in the development that you will have to puzzle out on your own. Secondly, the chemicals themselves may be obfuscated somehow. Thirdly, the original developer may have made exclusive arrangements with sellers before releasing it at all, and thus before you could get your mitts on it. (at least without violating laws regarding trade secrets and corporate espionage, which are different kettles of fish)

      But just wait until we have nanotech assemblers that can anaylze a car, or a pill, or a piece of food and replicate it perfectly. (given time, energy and raw materials) It's going to utterly destroy the economy, and require a new one built on top of it (because so few goods will remain scarce) and can be previewed with regards to the current battles with copyright and patent law.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    27. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      Hey pal,

      Military research includes drug research. But I guess being the self-righteous ass you are, you failed to see past your ideological blinders and look at the truth. Now please go crawl back into your third world hole before I sic the dogs on ya!

    28. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      I thought that the rain forest contains every medicine mankind needs. Maybe the brazilians just don't have time to search for it.

    29. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      Brazil nor any country will break ALL aids drugs patents.
      If someone read the articles, saw that the government tried a price reduction, but roche ofered only 13%.. For a drugs that represents more than 30% of the total cocktail cost, it's ridiculous.
      Anyone has here listened of the scale market..
      Why selling for $2000 a drug that costs (including the research) $200 a year?
      Only the europeans and americans can afford it..10% of the world..
      sell it for $400 and 90% of the world can buy it..

      Brazil only showed that if the companies don't want to HELP, no matter.

      How many PRIVATE companies research the aids VACINE? i know of NONE.. why? vacine will cost the same a drug costs...but you will need it once or twice in lufe, not every day...

    30. Re:Way to fucking GO!! by GungaDan · · Score: 1
      "Making bucketloads of cash ENDING other people's misery"

      You incorrectly imply here that the pig-at-trough industry is curing disease. This is not the goal of the drugcos. They prolong the lives of people with HIV so that those people can continue to buy their outrageously overpriced product. They find cheaper ways to make insulin instead of curing diabetes. There is virtually zero novel vaccine research and production in this country because vaccines are a one-time (read: non-profitable) deal. And on that last point, let's hope you don't get tetanus anytime soon, 'cause there's a severe shortage of that vaccine owing to the shutdown of manufacturing facilities because of the lack of revenue produced by those labs.

      Drugcos are not knights in shining armor that some people make them out to be. The industry is parasitic, and like any parasite, it aims to bleed its host until that host is of no more use to it (i.e., dead or poor). The industry does not exist for a cure.

      --
      Eloi are stupid, throw morlocks at them!
    31. Re:Way to fucking GO!! by rjamestaylor · · Score: 1, Troll
      Way to fucking GO!!
      What an unfortunate modifier to use in a story about AIDS. Unfortunate because of the juxtaposition between the disease and the most common method of spreading/contracting it.

      What I've never understood is that, depending on context, a certain "life-style community" associates itself with or dis-associates itself from this disease. In fact, the contexts in which the switch occurs are criticism and funding. If you criticize this "lifestyle community" for their actions which spread/contract AIDS, the response is "AIDS isn't our disease." Yet, when it comes time to push funding to Find A Cure, the same "lifestyle community" leads the charge and calls the ones not gung-ho for this effort as "lifestyle community"-phobic.

      I think AIDS: the first disease to be political. Sad.

      --
      -- @rjamestaylor on Ello
    32. Re:Way to fucking GO!! by Sellaro · · Score: 1

      Iteresting this point of view. But I see, as a Brazilian, that the point is not lack of time. Brazilian government does not invest a resoanble ammount of money on research AND private enterprises do not have maturity level to "explore with feedback" these resources, what leads the government and public opinion to disagree with private investiments on Amazonia.

    33. Re:Way to fucking GO!! by AlefOne · · Score: 1

      OK, what disease is the "time and place" for profit? Heart disease? Cancer? No? What about hemophilia?

    34. Re:Way to fucking GO!! by Delphis · · Score: 1

      Maybe Brazil would have the cure anyway if you didn't all cut down the rainforests to make a quick buck, with no thought to the resources lost by such actions. AIDS cures etc. Brazil could be in the lead of producing these instead of merely burning them down to farm on, then moving on to the next area and the next.

      --
      Delphis
    35. Re:Way to fucking GO!! by kc0dxw · · Score: 1
      The right to a decent quality life is fundamental.

      Bullpucky. You are equating results with effort -- it is the effort which is an inalienable right, not the results of that effort.

      --
      Matt Meola AFOD
      Westminster, CO
      "Gun control means using two hands."
    36. Re:Way to fucking GO!! by Bobo+the+Space+Chimp · · Score: 1

      > Even here in the UK there have been a number of
      > high-profile decisions whereby the National Health
      > Service has decided not to provide life-saving (or
      > dignity-gaining) treatments purely because of cost.
      >
      > And the UK is supposed to be a developed country -
      in the top 20 worldwide.

      But would seeking that treatment independently be illegal? Had Clintons had their way, it would have been over here. In the Netherlands, the govt. provides (last time I checked, about 10 years ago) a minimum level of care, and you could buy better care on top of that. In UK, (correct me again) you can exempt yourself but only if you're rich, like worth > 5 million pounds. Still hardly optimal, and certainly having nothing to do with free choice.

      --
      I am for the complete Trantorization of Earth.
    37. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      quite right!
      might as well kill us all to make a quick profit.
      Still thats the AMERICAN way The sooner the UN puts troops on the ground to protect the worlds resources the better.
      And that goes for oil, wood, gas - the lot

    38. Re:Way to fucking GO!! by Von+Rex · · Score: 1

      No, patents == possibility to put billions in pharmaceutical bank accounts while spending additional billions on advertising and bribing politicians.

      Drug companies set new records in profit every year while telling us that they just can't survive unless the US government stamps out anyone else in the world who would dare to (gasp!) produce medicine for the sick. Don't believe me? Check this out.

      Imagine if the current situation had existed when penicillin was discovered. How many millions of people would be dead just so American drug companies can have unprecented profits and pay their CEO's 40 million dollar salaries?

      Brazil should be commended for being the first country to extend the finger to American pharmaceutical companies. Brazilian leaders have said that the lives of their own citizens matter more to them than the profits of foreign executives. Only now, and only here, would this be considered a radical position. Hopefully the rest of the world will eventually follow suit.

    39. Re:Way to fucking GO!! by jbarnett · · Score: 2


      English is not my native language, is that a crime?

      Dam staight it is a crime. I see how you non-english speakers are... reverse engineering (learning) our launage by snooping (listening) to random converstations. I think English is copyrighted.

      --

      "`Ford, you're turning into a penguin. Stop it.'" -THHGTTG
    40. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      I have just been granted a patent for the device you describe (a matter replicator). I will start manufacturing these in the year 8379, 6378 years from now. Please be patient. there are only a few minor bugs to work out of the system. The only problem with your analysis is that the use of my replicator will not be free. Objects manufactured with this CAM machine will be sold for roughly double the price of a conventionally manufactured product.

    41. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      Actually I will soon be filing for a patent on all linguistic systems, including English. This was all my idea and I expect the U.S. Patent office to agree with me wholeheartedly. So get ready to pay up whenever you so much as grunt (can be considered a verbal means of communication). Note that the word "English" is going to be one of my registered trademarks and you will soon have to refrain from using it without explicit written permission. Also, note that I, myself, will be paying royalties to the great man who recently patented patents themselves. Needless to say, I intend to enforce my patents, not only in my own country, but all over the world as well.

    42. Re:Way to fucking GO!! by susano_otter · · Score: 2

      There's a time and a place for all this profit-minded patent shite. AIDS ain't it!

      Indeed. Let's see now:

      • 1. Brazilian pharmaceutical companies are aware of a market for AIDS medicine.

      • 2. Brazilian pharmaceutical companies hold no patents for AIDS medicine.
        3. Brazilina pharmaceutical companies don't want to pay the patent license fees (probably because their potential customers wouldn't be able to afford the markup, [and|or] the fee payments would cut too far into their profit margin).
        4. Brazilian pharmaceutical companies cheaply manufacture AIDS medicine in violation of patent law, and sell it at whatever price the local market will bear.
        5. Conveniently, cashing in on the AIDS market has clear and laudable humanitarian side effects, greatly boosting the Brazilian pharmaceutical companies' popular approval rating and providing much-needed rationalization for the actions of the anti-WTO cartel.
        6. In fact, the actions of the Brazilian pharmaceutical companies will have repurcussions which will generally be viewed as beneficial by those who oppose the WTO.

      Don't kid yourself. The Brazilian pharamaceutical companies are doing this for the money.

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    43. Re:Way to fucking GO!! by susano_otter · · Score: 2

      Try this on for size: Pharmaceutical companies seek to profit from the suffering of others. What if, instead of leaving medical research in the private sector, the government itself invested in improving the quality of life of its citizens? Sure, nobody would be making money off the AIDS medicine patent, but surely all those extra healthy taxpayers would result in more money for medical research, neh?

      Unless this idea is too socialistic for you. Would it help if I substituted "taxes" for something more libertarian, like "voluntary community improvement donations"?

      --

      Any sufficiently well-organized community is indistinguishable from Government.

    44. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      Don't kid yourself. The Brazilian pharamaceutical companies are doing this for the money.

      You should consider reading the articles sometimes. The GOVERMENT will produce the medicine, to be distributed for free.

    45. Re:Way to fucking GO!! by chris_mahan · · Score: 1

      I've got to agree with you on this one...

      A truck engine can go 1,000,000 + miles, but my car's can only go about 150,000 before dying? I'm not pulling a 40 ton tractor either. It's just that they want to create an ongoing dependency on their product, that's all.

      --

      "Piter, too, is dead."

    46. Re:Way to fucking GO!! by Thomas+M+Hughes · · Score: 2

      Funny how greedily searching for solutions to others' miseries, miseries that those suffering pray for a solution to, solves those problems all the while people stand on rocks pontificating how evil that process is. Yet when you look in their socialist bag, you don't see too much at all.

      Really? I see Brazil giving hundreds of thousands of disease infected human beings cheap drugs to help them with their medical problems. That's not much at all? Compared to the Capitalist solution of "If you're not going to make us billions of dollars (which you can't afford to pay, while we live in our expensive apartments and drive BMW's), you don't deserve to live."

      Right.

    47. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      I work for a pharma company, and let me tell you... there isn't a big bucket-full-o-money that we all take fistfulls from each day. The starting salaries that most pharma companies offer are at market averages. The idea that you could eliminate the profit making potential for aids drugs and still have any developed is pretty fucking stupid. Way to "not fucking go". Pharma companies target drugs that will make money, and unless tax payers are willing to pay part of their taxes to subsidize aids research, say bye to a cure in the near future...

      People like spending money on what they WANT, but complain about buying things they NEED.

    48. Re:Way to fucking GO!! by Clived · · Score: 1

      Well said !!

      Here at last is a country whose government has the
      absolute "BALLS" to put the well being of their
      people before the immoral interests of multinational corporations who seem to answer to none these days. Its good to see that at least one government has placed value on the morality of this issue .. " some of its population in dire need versus quarterly profits of the multinationals".

      -- Sir, without a need for money, the challenge is for us to become better people .. Captain Picard .. Starship Enterprise--

      --
      Clive DaSilva Email: clive.dasilva@gmail.com Ubuntu 18.10 Kernel 4.18
    49. Re:Way to fucking GO!! by aprentic · · Score: 1

      Making bucket loads of cash ending peoples misery
      with research done on other peoples tax money.

      Almost all medical research is funded by grant money. Huge amounts of this money get paid for by
      tax dollars.

      Given that the public is already paying the bulk of the cost for these medications they shouldn't have to pay again to reap their benefits.

    50. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0

      I know that no one will probably read this, but I have to make a few comments. First off, to all the posters/readers who say "Way to go, Brazil. You are screwing it up for everybody", let me say that you talk a big game... FOR SOMEONE WHO DOES NOT HAVE AIDS!! I could only imagine how quickly and starkly, you would change your tune, if you had AIDS. (Why is it that the Nerds/Engineers have such a hard time empathizing for others?)

      Next, for all of those who say that this is cutting into the drug company's profits, and it will stop research in the future: The Pharmaceutial Industry is the *most* *profitable* industry in the United States. More than car makers, computer makers, OS makers, utilities, oil producers, accountants, lawyers and entertainers. This is after they pay leases, electricity, water, heat, capitol expenses, benefits, salaries, bonuses, stock dividends, lobbying, lawyers, advertising... AND RESEARCH!! Please take a moment and ponder that.

      The Pharmaceutial Companies are not merely trying to get a return on their investment. They are squeezing every last cent they can get out of us!!
      And the United States is the biggest grape of them all. For many people it is more cost-effective to travel to a foreign country, just to fill their prescriptions!

      And if you heard the NPR report on the matter, you would have learned that Brazil is not going to totally ignore the patent, they are planning on producing it for their citizens, while paying a *smaller* royality to Roche.

      Again, it may be too late, but someone please mod this up.

      I'm AC--but I'm not that AC!

    51. Re:Way to fucking GO!! by Anonymous Coward · · Score: 0


      Well, there was a message here but this moronic board tells me i'm posting to fast and discards the text!

      Get the bugs fixed jerks!

  2. Imagine that... by briggsb · · Score: 2

    How could it be in this day and age that lives are more important than money and intellectual property? I must have not woken up yet, and must still be in a dream world.

    1. Re:Imagine that... by thetman · · Score: 1

      Well, you'll find that if we continue stealing intellectual property from the drug companies, then they won't be too interested in developing these drugs in the first place, so then not only poor people won't be able to get a life saving drug, no one will be able to. A lot of slashdotters would consider this a good thing. Oh, just wait, the open source crew will step in and develop all the drugs we need for free, just like linux!.....Right.....

    2. Re:Imagine that... by briggsb · · Score: 1

      I'm fully aware of the implications, but I have a feeling that it will always be profitable to make drugs that save people's lives.

    3. Re:Imagine that... by geekster · · Score: 1

      What about letting it goverments pay for it through tax money?
      For the public by the public. Seems a lot more right than putting it in the hands of companies...

    4. Re:Imagine that... by Tackhead · · Score: 2
      > I'm fully aware of the implications, but I have a feeling that it will always be profitable to make drugs that save people's lives.

      I admire your optimism.

      Personally, I don't think we'll ever see a vaccine for AIDS, or a cure for cancer. Ever.

      If polio were still around, we'd see plenty of drugs to "manage" the condition, maybe even a portable "iron lung" breathing-assistance apparatus using "smart wire" that changes shape when electrical current is passed through it.

      But what we would not see is a vaccine, a'la Sabin or Salk, that costs less than a dollar per dose.

      Teach a man to fish, and thank you tomorrow. Feed a man a regimen of three different species of fish every eight hours, and he's a revenue source for life.

    5. Re:Imagine that... by Bobo+the+Space+Chimp · · Score: 1

      Only insofar as there are a handful of logical countries that allow them to make profits from this.

      If every country "pulled a Brazil" on this, you can be guaranteed many more deaths in the future from drugs delayed or denied discovery or creation.

      Those phantom future millions, though, don't show up in most people's analysis (certainly not in any politician's analysis.) No one (sadly) says, "Hey, FDA, how many are dying now because of delays in drugs?" That's a number magnitudes larger than the number the FDA saves preventing premature introduction of harmful drugs.

      --
      I am for the complete Trantorization of Earth.
    6. Re:Imagine that... by Anonymous Coward · · Score: 0

      Like the phen-fen combo?

    7. Re:Imagine that... by Anonymous Coward · · Score: 0

      If you believe that lives are more important than money and IP, then you have woken up. It's the people who think that money and IP are more important, they're the ones who are still asleep.

    8. Re:Imagine that... by MrDolby · · Score: 1

      Yes, lets see Brazil or South Africa setup their own medical research and then allocate the funds to research and develop AIDS drugs.

      Doing all this on tax dollars paid by the corporations and working citizens of the country.

    9. Re:Imagine that... by mimbleton · · Score: 1

      How is that different than typical insurance beside the fact that goverment run programs ussually have much greater rate of waste and corruption as compared to privately run ones ?

    10. Re:Imagine that... by briggsb · · Score: 1
      Yes, I am an optimistic person by nature.... Your comment...
      Teach a man to fish, and thank you tomorrow. Feed a man a regimen of three different species of fish every eight hours, and he's a revenue source for life.

      Rings true, and only re-enforces my thought that maybe the whole patent system should be re-thought.

    11. Re:Imagine that... by Anonymous Coward · · Score: 0

      I disagree. Since you seem to imply that profit is more important than saving lives, clearly any drug company that discovers a cure for a disease would rather hang on to it and instead release a series of "symptom management" drugs designed to cost a lot and last a long time (ie: far more profit potential than a one-hit cure wonder). Pure profit motivation for discoveries is JUST AS BAD as having ZERO IP rights, and that is why the patent system originally was invented.

    12. Re:Imagine that... by T.Hobbes · · Score: 1

      Th drug companies only produced the drug because there are people in the first world who can afford their $1k a month or whatever it costs. If AIDS was limited to the third world, it woudn't have been produced in the first place, irregradless of incidents like this. You're point is moot.

    13. Re:Imagine that... by Lemmy+Caution · · Score: 1

      Then why does the US pay more and get less for its medical dollar than most any other country? Do you have any evidence for your claim, or are you just repeating it as an assumption?

    14. Re:Imagine that... by mimbleton · · Score: 1

      What do you mean ?
      I find US healt care much more superior to anything I experienced in Europe ( and I lived there for about 20 years)

    15. Re:Imagine that... by No+One · · Score: 1

      Oh, yeah, sure. They'll just abandon their legal responsibilities to their stockholders and go out of business. I'm sure the officers really want to be sued into oblivion.

      No, they'll keep researching the drugs, because that's how they make money. Besides, they'll still have the right to patent publically funded research. Get real.

      --

      There is no sin except stupidity -- Oscar Wilde
    16. Re:Imagine that... by chris_mahan · · Score: 1

      So it's okay for people who are alive right now to die so that people who are not yet born will have a chance to live longer?

      With that reasoning, let's have a war, and kill all the people alive today who are lazy, poor, and ignorant (5B or so). So that in 50 years, the gene pool will be better, and people will work harder, be better educated, and be nicer to each other and live longer.

      Yeah right.

      Pollution kills people. Overpopulation produces pollution, therefore: reduce population. Methods? War, Aids. Let people die of aids. (What kind of people? See above paragraph).

      Is that what you propose?

      That is INSANE!

      Heck: Even better, why don't we make air quality so bad that all people in cities will die around 62 1/2 of lung-related diseases, and only super rich people with houses in Aspen or the like will live to a ripe old age of 85. Heck, that will Save Social Security, no?

      Ok. I feel better now...

      --

      "Piter, too, is dead."

    17. Re:Imagine that... by Anonymous Coward · · Score: 0

      --No one (sadly) says, "Hey, FDA, how many are dying now because of delays in drugs?" That's a number magnitudes larger than the number the FDA saves preventing premature introduction of harmful drugs.

      How many people might die because the population is afraid to take drugs?

      Issue tend to have more than two sides.

    18. Re:Imagine that... by geekster · · Score: 1

      I was thinking more on contries who can afford to do so, who would then share their knowledge instead of a some company making a business out of it.

  3. India, Brazil, China... half the planet already! by CSC · · Score: 1
    Things shape up on the "our money vs. their life" front.

    Medicine has been corporate property for far too long already.

    --
    -- Colin
  4. Example? by sllort · · Score: 3, Insightful

    "This may set an important example that public needs justify the disregard of patent protection"

    It sets a few more examples, too. If you're an AIDS patient, it sets the example that you should fly to Brazil, right away. If you're a drug company, the example is to look into carpet bombing Brazil, and if that fails, stop developing drugs no one will ever pay you for.

    Just because software patents are patents on math & therefore stupid doesn't mean all patents are stupid. Pharaceutical R&D is intensely expensive. Screwing the companies that fund research is a bad solution to what is at heart a political problem.

    1. Re:Example? by Jedi+Alec · · Score: 1

      Screwing the companies that fund research is a bad solution to what is at heart a political problem.

      Ehmm, what exactly do you mean by that phrase? *What* is a political problem in your opinion?
      --

      People replying to my sig annoy me. That's why I change it all the time.
    2. Re:Example? by CSC · · Score: 2, Insightful
      Screwing the companies that fund research is a bad solution to what is at heart a political problem.

      A political problem?

      No. The political problem appears when Brazil decides that life is more important than the stock quotes in some other country far north.

      Brazil thus transformed an ethical problem into a political problem. My opinion is, it's a net gain.

      --
      -- Colin
    3. Re:Example? by r1ch · · Score: 1

      You make some good points, but what you're forgetting is that Brazil is an intensley poor country with a huge AIDS problem. They do not have the money to pay for the treatment and so the alternative is death. At the end of the day, IMHO, this will make virtually no difference to the drugs companies, but a massive difference to people's lives.

    4. Re:Example? by tommck · · Score: 1
      [Disclaimer]
      • I am not trying to take medication out of the hands of people who need it.
      • I am also not saying that the drug companies have been giving the drugs away at low, low prices.
      • I don't work for any drug companies.
      [/Disclaimer]

      I completely agree with this post. If everyone does this, it will have the effect of terminating drug research. If there's no money to be made after spending US$500 million researching something, then it won't be done! Then, we'll all die in the streets of Code Red XXV infection!

      --
      ---- It puts the lotion on its skin or else it gets the hose again. It does this whenever it's told.
    5. Re:Example? by evilned · · Score: 2

      Yes, drug R&D is intensly expensive, but a significant amount of that research cost in many cases is publicly funded. In those cases, I really dont think the drug companies should have the right to patent it. I'm all for private companies making a profit when its their money at risk, but corporate welfare has to stop sometime.

      --

      "My head hurts, My feet stink, and I dont love Jesus." -Jimmy Buffett

    6. Re:Example? by big_groo · · Score: 1

      I agree, however, a great deal of money that goes into research comes from grants and bursaries from private organizations and *taxpayers*. What is the budget for AIDS research in the US alone? Did the company base their drug on any previous works done by public organizations?

      I don't specifically agree with Brazil's decision but this is human life we're talking about. What's more important to you? Making the _big company_ a few more bucks, or preserving quality of life ? I personally think Brazil is going to get away with this one. If it were a cough medicine, or something more mainstream, then no. Other countries (read: Africa) will be sure to follow their example. In Africa people are dying of AIDS at an alarming rate.

      This is an ethical debate. Not political.

    7. Re:Example? by Anonymous Coward · · Score: 0

      very little of actual drug testing is done with public money, most goes to actually reseaching the desease not curing it.

    8. Re:Example? by kalifa · · Score: 3, Insightful

      > Just because software patents are patents on
      > math & therefore stupid doesn't mean all patents
      > are stupid. Pharaceutical R&D is intensely
      > expensive. Screwing the companies that fund
      > research is a bad solution to what is at heart a
      > political problem.

      There is some truth in this, however these companies would have more credibility if they did not spend much more on advertising, public relations, lobbying, sponsoring sports events, etc., than on research.

      There is currently a bill which is about to be passed in the EU which would allow advertising on prescribed drugs, as it is already the case in the US. I hate this idea. It encourages overconsumption of drugs, it diverts billions and billions of dollars (or are they euros?) from more useful tasks, and it encourages pharmaceutical companies to focus on comfort-oriented drugs, made for wealthy retired in Florida or in the south of France, rather than on life-saving drugs.

      Today, drug companies fight against each other with marketing, lobbying and politics: millions and millions are poured into "lobbying" (read: corrupting, but legally, the typical American way) drugs-regulation authorities, to make sure that competing drugs are not approved, or that the approval is delayed, to make sure that their exclusivity on a product is extended, etc...

      Inventive, good-for-humanity research is secondary. These companies will be allowed to complain on what is going on in Brazil when they have changed their ways.

    9. Re:Example? by Hard_Code · · Score: 2

      The pharmaceutical companies are hardly screwed. There was no guarantee that after they made the drug they'd get rich from epidemics in Brazil and Africa. Profits are not a *right* (something MPAA and RIAA are also having a hard time getting their heads around...they continually are going to Washington whining, "hey, it's not *fair*...we *expected* to make lots of money and now we're not, boohoo"). Anyway, patents are useful insofar as they benefit the society (and extended to international patents, the whole global society) as a whole. If some pharmaceutical makes less money because the global community decides that millions of lives are more important, guess what? - Tough shit for them. The benefit to society of saving millions of lives in this case far outweighs the benefit to a very few of making lots of money.

      --

      It's 10 PM. Do you know if you're un-American?
    10. Re:Example? by why-is-it · · Score: 2

      Pharaceutical R&D is intensely expensive. Screwing the companies that fund research is a bad solution to what is at heart a political problem.

      How is AIDS a political problem?

      And while R&D might be expensive, Big Pharma is still making coin hand over fist, and none of the drug companies are getting out of that industry because it is not financially viable

      The issue is that Roche (et.al.) want to charge more for a few doses of drugs than people in third world countries can expect to make in a year. This is clearly unacceptable.

      --
      *** Where are we going? And what's with this handbasket?
    11. Re:Example? by SubtleNuance · · Score: 2

      stop developing drugs no one will ever pay you for

      or turn over pharmaceutical research duties to Universities. That way the Uni's can peruse research that leads to *HEALHTY PEOPLE* and not to simple economic-profit.

      Pretty Fucking Simple(R)(TM) isnt it.

    12. Re:Example? by Hard_Code · · Score: 2

      Oh, and by the way, if you conclude through extrapolation that the failure of pharmaceutical X to make lots of money because society decides there is a greater cause, immediately disincentivizes the whole industry (leading of course to the collapse of civilization as we know it...or something), I suggest you reexamine your assumptions about the motives for doing such work - for example, it's taken for granted that people *will* work without compensation on many things, e.g. Open Source software. In an extreme case, I'm sure the death of one given pharmaceutical company is not going to destroy the entire future of human research into pharmaceuticals.

      --

      It's 10 PM. Do you know if you're un-American?
    13. Re:Example? by Anonymous Coward · · Score: 0

      Considering that a person carrying HIV having sex with another and NOT telling them about their infection is essentially assualt with a deadly weapon. In most cases could be considered submitting somebody to a long torturus death sentance. THe best thing would be to prosecute anybody spreading the virus intentionally and sentance them to death. That would be a quick way to end the HIV problem.

    14. Re:Example? by wct · · Score: 0, Offtopic

      Damned right.

    15. Re:Example? by Anonymous Coward · · Score: 0

      Really dude, the people in Africa hav such screwed up ideas like if an HIV positive person has sex with a young virgin they can be cured. This beleif is causing mass rape and continuing infections. The leaders over there wont even accept that HIV is a medical condition, rather that is cause solely by poverty. Hell even the African-american leaders are saying that they "wont let the rest of the world pin this on them". So instead of taking responsibility for their actions (gee lets rein in our libido's, they pass the buck.

      You know what the hell with them. When Africa is nothing but an empty content devoid of humans, there will be alot of coast property for sale.

    16. Re:Example? by Anonymous Coward · · Score: 0

      In sweden the government in the 80's stole companies money. This was taxed money that those companies has earned and payed taxes on.

      The government said the society could use those money better.

      It ended in one big financial collaps because:

      1: Companies stopped innovating, whats the point in spending huge $$$ on researching something when it isn't possible to make money on it. It just don't happen.

      2: Some companies fleed the contry (and their owners was hunted and harrassed by the tax authority for it) and huge unemployment followed.

      It's quite clear that if we want more drugs to be developed the companies MUST be able to take patents on them. Noone can spend billions of dollars on researching something and then anyone can just copy it right away and just manufacture it. It will not happen.

      Personally I would like a solution where rich contries payes more for drugs and poor ones less but it may be diffucult to implement in reality.

    17. Re:Example? by thetman · · Score: 1

      Ya, actually its a social problem. Here we have yet another one of those strange coincidence of life, that the societies that can't control aids through education behavior modification also are the same ones that don't have the money to pay for medicine to treat the results of their behavior.

    18. Re:Example? by sllort · · Score: 1, Flamebait

      How is AIDS a political problem?

      AIDS is not a political problem. The refusal of the Brazilian government to allocate the funds required to purchase the drugs necessary to save the lives of their citizens IS a political problem. By choosing instead to steal, Brazil has established itself in the world community as a thief of intellectual property on par with China, but without the manufacturing muscle to get away with it.

      And they will pay the price.

    19. Re:Example? by codeforprofit2 · · Score: 1

      That is untrue, public money mostly goes to "wide" knowledge of the human body and deceases. Very rarly specific deceases and possibly cures. It's aimed as better understanding whats going on in the body.

      The public work is important as a ground for those companies but it it's a substitute by any means.

      If we take away patents, we take away those companies possibility to develop new drugs.

    20. Re:Example? by sllort · · Score: 2

      or turn over pharmaceutical research duties to Universities. That way the Uni's can peruse research that leads to *HEALHTY PEOPLE* and not to simple economic-profit.

      Yes, let's dump a task with the potential for massive financial gain or loss squarely on the shoulders of the academic researchers we depend on to serve as unbiased and objective observers of commercial science. That way, we'll have no one who can't be bought off by pharmaceutical money, and we'll just have to believe everything they tell us.

      Great idea.

    21. Re:Example? by Anonymous Coward · · Score: 0

      Taxpayers money are rarly spended on specific issues but mostly on trying to broaden the general understanding about the human body and deceases.

      This research is an inportant basement for drug companies but without those companies we are screwed. There just is no way we are going to see new drugs without the possibility for those companies to protect their investments.

      "a few more bucks"

      It isn't about making a few more bucks, it's about making it possible at all for companies to develop these drugs.

    22. Re:Example? by Anonymous Coward · · Score: 0

      Maybe they just don't HAVE that money, should they let _PEOPLE DIE_ just because they lack some bits in their bank accounts? I really don't think so, this fsck:in "money" thing is really starting to feel like a baaaaad idea... when does someone find a better solution? Communism didn't work, at least not the USSR style one, now it seems that people are respecting money more then human lives - it doesn't work like that either, looks like we need something new.

    23. Re:Example? by KarmaBlackballed · · Score: 2

      ...stop developing drugs no one will ever pay you for.

      That is an oversimplification. Do you follow the news? For example, the makers of Prilosec (Costs over US$100 for 30 pills) are suing a generic drug maker now as a manuver to extend their patent protection beyond october. And this manuver will work. That is the reality of our patent system. Their patent has already been in effect for 13 years. They make over US$100 million per year on this drug. Excuse me, how many years do you need before you recover your RD costs and pad your pockets real good?

      Stop being brain washed. It isn't healthy.

      --

      --- -- - -
      Give me LIBERTY, or give me a check.
    24. Re:Example? by Jedi+Alec · · Score: 1

      That's a problem that occurs both on individual and national levels. Once poverty strikes, you won't have any money left to keep up your infrastructure, resulting in communication breaking down, which is why it is so hard to re-educate people. And considering the Brasilian temperament(no this is not a prejudice, I know what I'm talking about), you won't get away with a "do this" or "do that". You'll have to give some good reasons.

      --

      People replying to my sig annoy me. That's why I change it all the time.
    25. Re:Example? by Flower · · Score: 2
      It's eminent domain. The cost of treating the victims and paying the drug companies is too high for Brazil. Paying massive fees to the drug companies will not make the country as productive as treating its citizens. This isn't a Gordian knot here. Treat your citizens first. Worry about the non-Brazilian drug companies later.

      One may argue that this sets a bad precident but oh well. There are other first world countries which will front the costs for R&D. I don't see why this should bother Brazil's government at all. Hey, if there was a fatal disease that infected 25% of the American population and the only way to maintain it (not cure you, just keep you going) was a $1000/month treatment you know the first politician who ripped that patent out of some company's hands and developed a $10/month treatment would wind up President.

      --
      I don't want knowledge. I want certainty. - Law, David Bowie
    26. Re:Example? by LordNimon · · Score: 2

      Pharmaceutical companies spend more money on marketing than they do on R&D. I don't have a source for that information I can quote, but I did read it on a news site a few weeks ago.

      --
      And the men who hold high places must be the ones who start
      To mold a new reality... closer to the heart
    27. Re:Example? by Peter+Harris · · Score: 1

      Or...

      Countries that can club together to fund necessary research will thrive, (and so will everyone else of course). The EU is easily big enough to do this. The ones with a national health service will save a fortune on non-patented drugs.

      Obviously if private drug profits are enough to fund patented research then the savings on drug costs would be enough to fund public research.

      Pharmaceutical companies will make money from research services and drugs manufacture (work) instead of IP ownership and licensing (blackmail).

      No joy to the corporatists, but *they* can die in the streets for all I care :-)

      --

      -- What do you need?
      -- Gnus. Lots of Gnus.
    28. Re:Example? by zothorn · · Score: 2, Informative

      Case in point. The company that I work for is having to upgrade a lot of systems to meet the new 21 CFR Part 11 FDA requirements. Some of the systems like single pieces of lab equipment cost $300,000 USD! Plus things like $20,000 yearly for support, updates, and repairs. Multiply this times hundreds of labs times 30 countries. And you can see billions being spent yearly just to make sure the equipment is up to date.

    29. Re:Example? by elefantstn · · Score: 2
      Other countries (read: Africa) will be sure to follow their example. In Africa people are dying of AIDS at an alarming rate.

      I wouldn't count on it. Cost of drugs is not what's keeping African nations from treating their people. There are a myriad of other reasons. In South Africa, one of the worst-hit nations, AIDS drugs were offered at 33% of the cost in the US, but were refused. A year later, they were offered free, and were still refused. The government's stance on HIV (a state of denial) prevented them from accepting any help at all. Once the drugs were accepted, another problem came up: the people didn't have enough food to take the drugs. AIDS drugs have heavy side-effects, especially when taken without food, and the most poverty-stricken South Africans became desperately ill when they tried to take them on an empty stomach, so they stopped taking them.

      The point is, basically, that the cost of drugs isn't the real problem in Africa, it's the more widespread effects of poverty and political ineptitude.

      --
      If it ain't broke, you need more software.
    30. Re:Example? by Anonymous Coward · · Score: 0

      Meanwhile the pharmaceutical industry spends more money on lobbying and campaign contributions than any other industry. http://www.house.gov/bernie/statements/2000-05-03- pharmprofits.html

    31. Re:Example? by DCheesi · · Score: 1
      Personally I would like a solution where rich contries payes more for drugs and poor ones less but it may be diffucult to implement in reality.

      Well, as long as we don't send in the troops to enforce patents in third-world countries, this is what will probably happen, at least with crucial life-saving drugs. Those of us who live in the United Corporations of [America/Europe] will continue to pay high patent-based costs for medication, while the poorer countries (who can't afford to pay anyway) will make their own generic supplies. So the drug companies will continue to make money in their primary markets, and the poorer nations will benefit.

      Nah, who am I kidding? The corporate armies are probably mobilizing as we speak...

    32. Re:Example? by eXtro · · Score: 1
      Well, government contributions are by definition fungible. To develop a drug research into the disease has to be done. Even if government gives money for "research on disease X", and its only used on "research on disease X" its money that the drug companies then don't have to spend. So more drug company dollars can go towards making a cure (or alarmingly, marketing).


      There's nothing wrong with this, the important thing is that the research is done and eventually a cure comes about. It does muddy the statement that "only private money was made to find the vaccine" though.


      So, public funds are used to develop vaccines through the redirection of corporate funds that would have been spent.


      Is Brazil's actions wrong? I'm not so sure. Ethical standpoints on patents or the value of human life aside, patents are in place to allow public disclosure at the cost of providing an artificial monopoly for some period of time. You're allowed to make use of the patents for non-commercial purposes, which I think Brazil's case qualifies for. If Brazil suddenly started selling their drugs then (again, ignoring ethical statements) they would be in the wrong.

    33. Re:Example? by Pyrosz · · Score: 1


      Have you ever been to Brazil? No? I didnt think so. They are a Very poor country for the most part. I suppose that the word poor skips over your real grasp of it. Poor is not when they cant afford internet any more. Its where they cant afford running water, let alone clean water. The only political problem they have is in education of Brazilian people on the effects of AIDS. Although this doesnt seem to work as you can just look at our own "educated" public and look at how many new cases of AIDS there are every single day. I dont totally agree that they should just break this patent and use it as they wish, but what choice did they really have? They want to save their people from Death. They could have talked with the company I guess, maybe they did and where turned down? Who knows. These companies charge $100's of dollars for ONE pill. Most of these AIDS patients need more than one pill per day. This is just plain greed. Oh they do have to pay for the research, but Im sure they do that and then some in the first few years the new drugs out. After that they should drop the price to cover their expenses of production. Not to mention that some of this research is at publicly funded research facilities such as Universities. These companies give a big grant to them and in return get the IP to the research. Hmm didnt I just pay for some of that? </rant>

      --

      An optimist believes we live in the best world possible; a pessimist fears this is true.
    34. Re:Example? by jd · · Score: 2
      Is it expensive because that's an inherent part of the research, or is it expensive because - up to now - there's been absolutely no incentive to keep the costs sensible?


      Let's stop and think about this, for a moment. Let's say there's some drug company A, which currently:

      • Uses a lot of animal research (expensive on licences, expensive on security, expensive on animal feed, expensive on animals, and expensive on space)
      • Fills out patents for absolutely everything, valid or not (expensive on lawyers, expensive on patent filings, expensive on patent defences)
      • Has a PR department the size of a small city (just flat-out expensive)
      • Sponsors anything under the sun that might grab attention (ditto)
      • Has at least one upper management in the world's hundred richest (where's their income coming from?)
      • Has lawsuits from hell, from products which are seriously questionable (expensive isn't the word)
      • Has approval costs & campaign fund donations to cover (ditto)


      Now, let's say that this company were to streamline management, get rid of big, gas-guzzling company cars, switch as much as possible from animal testing to computer simulation at the molecular level, were to make prices affordable (rather than sponge off insurance companies), and were to dump all superfluous costs, would "research" still be expensive?


      I suspect you'd find that costs are artificially inflated. Because they -can- sponge off insurance companies, and charge what they like (because they know that direct sales will be negligable, and insurance companies don't care, cos they can pass on the costs to corporations), there is absolutely no reason for a drug company to make research optimal. (If anything, the high money throughput looks good on the balance sheets. Makes it look like they're doing something useful.)


      Powerful beowulf-style or MOSIX-style clusters cost next to nothing, compared to the kinds of figures these companies throw around daily. Computing power of this kind is enough to simulate nuclear explosions, where the physics is bleeding-edge (vaporised edge?). I think it can handle chemical interactions in a human body, where the systems are much less, ummm, explosive, and reasonably well-behaved.


      Once you know the energies of each chemical bond, the valency of each atom, and the chemical structure of each compound, the rest is fairly simple maths. Provided the energy of an interaction exceeds the threshold at which a reaction will take place, the interaction will (generally) result in the lowest energy-state. That can all be modelled on a computer, without much difficulty.


      Add in that elements and compounds can substitute for something similar, that the body is awash with all sorts of reactive stuff, that "semi-permeable membranes" are only semi-permeable above a certain size of molecule, and aren't going to be permeable at all above some limit, that cells are horribly complex things, and that you've also got electrical circuits to play with, you can see it's not a trivial problem.


      But it IS a solvable one, and it is STILL well within the capacity of a large cluster.


      One such cluster can replace a large chunk of staff, all sorts of specialized animal facilities, other related expenses, etc, with a single piece of hardware that might take one or two people to maintain and can be re-used as often as you like.


      Sure, you still need "live" testing, but since you can do that AFTER you've done computer testing, you need much much less of it to get equal or better results. (The simulation will also give you clues as to what to look for, where, how, and when.)


      It would also all but eliminate the multi-billion dollar lawsuits, the need to excessive PR campaigns to stay on the public's good side, and all that other crap.


      In short, I cannot see a single reason why pharmacutical R&D is -inherently- expensive, only that it is because it's designed to be.

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    35. Re:Example? by Fjord · · Score: 2

      I see a net loss. When companies "up north" can no longer recoup their R&D they will being able to develop the drugs needed to combat diseases. Then a new disease and mutation will come out, and there will be no feasible way to fight it.

      This may work if only one country does it. But then why is Brazil allowed to do it while others aren't? All and all this is a bad situation.

      --
      -no broken link
    36. Re:Example? by Anonymous Coward · · Score: 0

      I can only begin to think of the reasons why this will be a disaster- medically, ethically, politically.

      1) This copycat drug will not be as safe as Roche's. Roche does a lot of R&D and quality control and safety monitoring on its products. Who will do this for Brazil's cheap imitation? The drug would be produced in some second or third rate lab--would you take this medication? Would you give it to your mother? If there is a contaminant in the drug that kills somebody or a large number of somebodies, whose problem is that? The government? The minilab that produces the drug? The government is about politics. It has no place in producing drugs.
      2) The company that contracts to make the drug is surely out to make a profit. Why should a random government contractor be allowed to profit from the R&D invested by Roche? What corners will this contractor cut to make it cheaper? Considering the volume production, Roche can probably do it cheaper but quality costs money.
      3) Putting patients on a single drug will be a virologic nightmare. Single drug therapy went out in the eighties. Patients need to be on three to four drugs to have adequate suppression of the virus. All single drug therapy does is select for resistant strains. What will happen when all the viral strains in Brazil become resistant to this one drug? Is Brazil going to make cheap imitations of all the AIDS drugs on the market because in order to do a decent job, that's what it will take.
      4) Drug development is expensive. The US government funds medical research, but they do very little drug development funding. Only drug companies are willing to risk the capital required to develop the drug, produce the drug, test the drug for safety and then market the drug. The whole process costs tens to hundreds of millions of dollars. Drug development isn't like software development- it isn't something that you can do in your garage. It takes a lot of time, lots of smart people and boatloads of money. Roche isn't like Microsoft. If Microsoft were to be wiped from the face of this earth, small developers and individuals could take over. If Roche disappeared, only another company as large as Roche could take its place.
      5) Although it might feel good for the big Goliath company take one in the gut, how will this affect the future if this trend in drug patent infringement reduces the number of NEW (not copycat) drugs becoming available.
      6) Where will the madness end. Does intellectual property really mean nothing? Think about what you do for a living. Lets say you spent years planning and studying and researching. How would you like it if someone STOLE your ideas and profited from them? They could do it cheaper too because they didn't invest years of work in planning and development. How long could you or your company stay in business if this happened all the time? (If you flip burgers for a living this probably doesn't apply to you.)

    37. Re:Example? by cpt+kangarooski · · Score: 4, Insightful

      It is difficult to discuss foreign patent systems unless you're quite familiar with them. I
      hesitate to do so.

      However, let's say, hypothetically, that it was the US that decided to do this, instead of
      Brazil. In that case, they'd be perfectly justified in that action. It would decidedly not,
      repeat NOT, be stealing. The patent holder was GRANTED that patent by the US because it was
      felt that doing so would have a public benefit. But ultimately, if there is a greater public
      benefit to be had in not granting, revoking, ignoring, etc. a patent, then THAT is the
      appropriate course of action.

      Yes, there is a danger that this sort of thing could remove incentives for the research to
      be done. That has to be weighed when making the decision: would the greatest public benefit
      come about by this course of action, even in the long run? Again though, the interests of
      the patent holder itself are not particularly important. No one can say with certainty what
      the result will be. The argument that patents are necessary is belied by the limited term of
      a patent; all patent holders lose the exclusivity of the rights to their invention, it's
      just a matter of time. Why? Because it is beneficial to the public that this be the case.
      It's highly unlikely that an everlasting patent (and the corresponding powerful, long-lived
      and dangerous monopolies that would arise) would really spur the inventor on. Or at least,
      that's the decision that's been made, and has been stuck with for centuries.

      Don't go around thinking that this is a bad thing. If Brazil fulfills its duty to its
      people, that's the most that can be hoped for. This type of decision does not prevent
      innovation, at worst (and its unknown if this will be the case) it merely slows it.

      You also make the mistake of believing that there is such a thing as "Intellectual
      Property." There is not. Any examination of the nature of property and the nature of
      information such as ideas will reveal the truth. Brazil cannot steal what is unstealable.
      And if they choose not to grant any rights to the inventor, there is no external authority
      from which the inventor might gain those rights. They do not come about as a consequence of
      his labors, they are a grant made by the government, at the direction of its citizens, and
      for some particular public aim.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    38. Re:Example? by GMFTatsujin · · Score: 1

      So you know how software prices go up and up in a pre-emptive attempt to recover costs from piracy? Ditto for tapes, CDs and DVDs?

      Is there a similar situation in the pharmacutical market? I mean, yeah, it's not as easy as downloading a copy of deViagra, burning the pill onto a cd and distributing it through Napster...

      I guess my point is, does the pharmacutical industry assume that somebody, somewhere is going to reverse engineer their Secret Sauce(tm) and start mass-producing knockoffs? In short, is the free AIDS drug in Brazil raising prices everywhere else to make up for the lost profit?

      Or could it perhaps drive the price *down*, as an incentive for the folks who only skirt the edge of the law to pay what could be seen as a more reasonable price?

      Hmm.

      Tatsujin

    39. Re:Example? by Fjord · · Score: 2

      You need a lot of years, because you aren't just covering the R&D of the successful projects, but that of the failed ones too.

      Stop being brain washed. It isn't healthy.

      --
      -no broken link
    40. Re:Example? by SubtleNuance · · Score: 2

      and we'll just have to believe everything they tell us.

      What - you cant read? The idea is transparent, repeatable, fully open reasearch... *everyone* would have to be part of a the coverup to misrepresent public research when it is fully disclosed.

      The present state is 'trade secrets' obscuring flawed-profit-motivated 'research'.

      Are you a troll or simply paranoid?

    41. Re:Example? by Anonymous Coward · · Score: 0

      But it's ok to screw the people who fund this reasearch, by this I mean the peope who paid taxes and those tax dollars went to tax breaks for the pharmas, and also to fund the research the pharmas patent later.

    42. Re:Example? by Erasmus+Darwin · · Score: 5, Funny
      "for example, it's taken for granted that people *will* work without compensation on many things, e.g. Open Source software."

      Announcing the release of OpenAntiHystX 0.2b:

      BECAUSE THE DRUG IS LICENSED FREE OF CHARGE, THERE IS NO WARRANTY FOR THE DRUG, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE DRUG "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE DRUG IS WITH YOU. SHOULD THE DRUG PROVE DEFECTIVE, YOU ASSUME THE COST OF ALL NECESSARY MEDICAL TREATMENT OR FUNERAL COSTS.

      What's new in 0.2b:

      • Removed a protein group that caused some people who're allergic to peanuts to enter anaphylactic shock, with potentially lethal consequences. Thanks to the widow of Jerry Henderson for reporting this.
      • The specified manufacturing process was resulting in residual benzene being left in approximately 4% of the pills in each batch. Temporary workaround applied (testing each pill) until we can come up with a permanent fix.
      • I've set up a paypal account so people can contribute to the FDA approval cost fund. It's still a long way off, but we should probably start saving up now.
      • I've had several people mail me about abdominal cramps. MAKE SURE YOU'RE USING THE LATEST VERSION. The abdominal cramp issue was fixed, along with several other bugs, back in release 0.2a.
      • After several round-table discussions with both RMS and the FDA, we've been able to agree that the licensing clause requiring development forks to use a substantially different name (so as to avoid consumer confusion) is acceptable within the Free Drug tenets.
    43. Re:Example? by zpengo · · Score: 2
      Inventive, good-for-humanity research is secondary. These companies will be allowed to complain on what is going on in Brazil when they have changed their ways.

      I don't think that companies should be deprived of their right to complain about theft simply because they advertise their products. That doesn't make any sense.

      They have a perfect right to complain. On the other hand, Brazil has a perfect right to tell them to stfu.

      --


      Got Rhinos?
    44. Re:Example? by mpe · · Score: 2

      Yes, drug R&D is intensly expensive, but a significant amount of that research cost in many cases is publicly funded.

      The expensive bit with drugs is trialling them to find out if they are safe and effective. Actual manufacturing is typically very cheap.
      The idea of drug patents is to make it worthwhile for privatly funded research. Problem is the drugs companies appear to be making huge profits, including on drugs where they may not have paid for the R&D in the first place.
      Also it's wrong to describe this as "breaking" a patent. It's more of a patent being revoked...

    45. Re:Example? by zpengo · · Score: 2
      How is AIDS a political problem?

      Simple: When all the citizens are dead, there's not much need for politicians.

      --


      Got Rhinos?
    46. Re:Example? by Anonymous Coward · · Score: 0, Interesting
      it will have the effect of terminating drug research. If there's no money to be made after spending US$500 million researching something

      If it's in the public's interest, the public will fund its reasearch. Rogaine, for example, is a drug that would have gathered no public funds and is for all intents and purposes a medically useless drug. Baldness causes nothing more than loss of vanity, which is not a social problem that the public needs to expend effort on solving. On the other hand, AIDS is killing people.

      How much of that $500 million figure (which I'm not validating in any way except as something you quoted) actually went into researching the drug? How much of it went into executive bonuses and stock options? I question the actual cost when its stated in these terms. If the people who volunteered themselves for testing the drugs got paid somehow I could see it. But where does that money go? Researcher's salaries? Let's suppose your average researcher gets paid $30 / hr. Let's give a new AIDS drug a team of 100 researchers and 5 years. That's $30,000,000 in salaries. Well did it take 100 people 5 years continuously working to come up with that drug?

      It's been my experience that most "costs" associated with business are pulled out of people's assess. It suposedly costs my company $60,000 to create a Windows 95 PC image. We (who create the images) don't have any idea where that cost comes from. I know I'd love to get paid that much to do a single image. At budget time these numbers are added up in some magical fashion and presented on a pie chart. I suspect that's how the "billions" the drug industry spends get quoted, too. Someone goes down into a lab and says "how much did that cost us to make?" and a number is fudged out of thin air. Let's see some real figures.

      All that aside, the company still manufactures the drug, don't they? They still have the brand name, don't they? Why is it a loss of money for them to have to compete with someone? This isn't like digital bits, where they can be reproduced at will. To create a drug, the drug company has to do some actual work, and their product cannot be casually copied and given to friends. I'm all for paying a drug company for their actual work. Their R&D could be acquired through a public grant, or they could just do what most people do with R&D, which is accept it as a cost of doing business. Honestly, when you put "intellectual property rights" vs. "massive loss of human life" I don't see much of a conflict.

    47. Re:Example? by shawnseat · · Score: 1

      Powerful beowulf-style or MOSIX-style clusters cost next to nothing, compared to the kinds of figures these companies throw around daily. Computing power of this kind is enough to simulate nuclear explosions, where the physics is bleeding-edge (vaporised edge?). I think it can handle chemical interactions in a human body, where the systems are much less, ummm, explosive, and reasonably well-behaved.

      Once you know the energies of each chemical bond, the valency of each atom, and the chemical structure of each compound, the rest is fairly simple maths. Provided the energy of an interaction exceeds the threshold at which a reaction will take place, the interaction will (generally) result in the lowest energy-state. That can all be modelled on a computer, without much difficulty.


      Bullshit. Computer modeling of chemical reactions is very primitive, even with the fastest computers available, and the problem is not very parallelizable; a lot of drugs are comprized of several dozen to a few hundred atoms. In vivo reactions are even more difficult, because of the vast number of proteins the molecule may encounter. Although inorganic reactions frequently do go cleanly to a single product, organic reactions, even in laboratory settings, often produce a wide array of products. Since the systems are much more complex in vivo, all reasonably possible reaction products (and with large molecules there are a /lot/ of them) must be checked for safety as well. If these simulations were as efficient as you propose, no one would hire synthetic organic chemists at all....

      --
      Religion is the opiate of the masses. The wealthy smoke the real stuff.
    48. Re:Example? by update() · · Score: 2
      Profits are not a *right* (something MPAA and RIAA are also having a hard time getting their heads around...they continually are going to Washington whining, "hey, it's not *fair*...we *expected* to make lots of money and now we're not, boohoo")

      No, profits aren't a right. Equal protection under the law is a right. The issue here is that these companies invested billions in research and testing on the expectation that if they found something useful, they could sell it under the same laws that apply to everyone else.

      Oh, and by the way, if you conclude through extrapolation that the failure of pharmaceutical X to make lots of money because society decides there is a greater cause, immediately disincentivizes the whole industry..

      Here's a less dramatic scenario: the companies decide not to bother developing drugs that save the lives of lots of poor people, preferring the safety of products to help wealthy people live another two years.

      I suggest you reexamine your assumptions about the motives for doing such work - for example, it's taken for granted that people *will* work without compensation on many things, e.g. Open Source software..

      Oh yes -- having gone through grad school, I'm very familiar with the idea that it's taken for granted that researchers will work 80 hour weeks for $15,000 a year until they're 30. I'd raise these questions, though:

      * Look at the range of quality on Freshmeat. Is that what you want to find in the drugstore?

      * I paid $1200 or so for my computer, $40 for LinuxPPC and nothing for Qt, KDevelop and gcc. Do you you see a problem in your extrapolation that researchers will therefore be eager to drop $100 million out of their pockets for compound screening and clinical testing? (Hint: I code for free, but I damn well don't pay the $100,000 a year that my research costs...)

    49. Re:Example? by crawling_chaos · · Score: 1
      Sorry, but this just doesn't work. The physics of a nuclear bomb explosion is several orders of magnitude of orders of magnitude less complex than simulation of animal physiology. There have been countless drugs that worked great in simulation or in a petri dish and were found to be totally useless or even harmful during animal or first-stage human trials.

      We simply don't know enough to create a simulation that can replace or even significantly reduce the use of animal testing, particularly for safety concerns. As it is, testing groups are kept small enough that some liver toxicity issues don't crop up until the product hits the market (Baycol anyone?). Abandonment of animal and clinical trials would only make this worse.


      Computer simulation is very useful, however, in finding drugs at the molecular level and in reducing the early-stage trials where the drug is tested in a petri dish against the pathogen. Far more research into basic animal physiology will be necessary before we can throw a Beowolf cluster at the problem.

      --
      You can only drink 30 or 40 glasses of beer a day, no matter how rich you are.
      -- Colonel Adolphus Busch
    50. Re:Example? by nathanm · · Score: 2

      Much of the research is already done at universities. Here at the University of Minnesota - Twin Cities, they helped to develop and owns some of the patents for the AIDS drug Ziagen, which was then licensed to GlaxoSmithKline. This is one of the drugs involved in the patent suit in South Africa earlier ths year. Many people here encouraged the university to make a statement about supporting lower prices for the drug. They did make one, albeit a very weak one. The problem is that the university like seeing the royalties come in just as much as the pharamceutical companies. It doesn't help that we're having a budget crisis caused by incompetent administrators & a runaway building program expansion.

    51. Re:Example? by spiro_killglance · · Score: 1

      Companies "up north" will still recoverer R&D for
      sales in rich countries, in North America and
      Europe. Brazil couldn't afford the drugs anyway
      so Roche have lost much money at all.

    52. Re:Example? by Bobo+the+Space+Chimp · · Score: 1

      > No. The political problem appears when Brazil
      > decides that life is more important than the stock
      > quotes in some other country far north.

      For now, but...

      > Brazil thus transformed an ethical problem into a
      > political problem. My opinion is, it's a net gain.

      For now...but what if all countries did this on all "important" drugs? Drug development is massively slowed, and the deaths start mounting by the millions because of slowly advancing technology -- people who wouldn't have died had technology kept advancing at a good pace. Millions, tens of millions, hundreds of millions.

      Yet, to a politician, or the hoi polloi, one death they can see (or prevent) today is worth millions tomorrow.

      --
      I am for the complete Trantorization of Earth.
    53. Re:Example? by Bobo+the+Space+Chimp · · Score: 2, Insightful

      > Profits are not a *right*

      As they derive from inalienable rights like the right to your own body, the right to property (property must be used to survive), and the right to deal with other people freely (right to your own body and their right to their own body), profits certainly are a *right*.

      --
      I am for the complete Trantorization of Earth.
    54. Re:Example? by clare-ents · · Score: 2

      I am told by a friend of mine who works for selling drugs to doctors that appoximately 70% of the cost of the drug is marketing expenses.

      Their marketing and legal team is substantially larger than R&D + production.

      --
      Only two things are infinite, the universe and human stupidity, and I'm not sure about the former. (Einstein)
    55. Re:Example? by feces_tossin_primate · · Score: 1

      Oh yeah, and the world is chock full of examples of "national health services" defeating epidemic-class diseases without the aid of those evil "corporatists".

    56. Re:Example? by feces_tossin_primate · · Score: 2, Insightful

      "...these companies would have more credibility if they did not spend much more on advertising, public relations, lobbying, sponsoring sports events, etc., than on research..."

      Speaking as one who has worked in IT in 3 different pharmaceutical companies, both in The EU and the U.S., I can say from personal experience that the apparently widely held view that these companies spend more on marketing than research is a crock. Please, I await just one post from just one /.'er who can quote from an annual report or a financial statement or any authoritative "neutral" source that proves pharmaceutical companies spend more on marketing/legal/FUD than they do on basic research and clinical trials.

    57. Re:Example? by screwballicus · · Score: 2
      1) This copycat drug will not be as safe as Roche's

      Apparently you aren't fully acquainted with what constitutes a "copycat drug". As an example, I will use a "copycat drug" with which I am well acquainted. I take Carbamazepine twice daily for epilepsy. Carbamazepine is just the chemical name used by generic brands for the commercial drug "Tegretol". The chemical structure of Tegretol is as follows:

      5H-dibenz(b,f)azepine-5-carboxamide

      The chemical structure of Carbamazepine is as follows:

      5H-dibenz(b,f)azepine-5-carboxamide.

      That's right. They're exactly the same. Carbamazepine is a molecule. The generic brand contains the same molecule as the commercial. They don't use "low quality atoms" or "bulk quality electrons" in the generic brand. They're the same high-quality molecular structures as in the commercial molecule.

      2) The company that contracts to make the drug is surely out to make a profit. Why should a random government contractor be allowed to profit from the R&D invested by Roche? What corners will this contractor cut to make it cheaper? Considering the volume production, Roche can probably do it cheaper but quality costs money.

      No, that doesn't seem particularly fair to Roche. Then again, it doesn't seem particularly fair that millions of people are dying of AIDS as we speak. Corporate fair-play may be a legitimate concern in the realm of corporate issues, but in the realm of human life and the preservation thereof, corporate fair-play doesn't rank high on my list of contravening issues. And this idea of a molecule having "quality" is coming up again. Troublesome one, that.

      6) Where will the madness end. Does intellectual property really mean nothing?

      It's not so much that intellectual property means nothing. It's more like...intellectual property means significantly less than the well-being of the millions currently suffering - and suffering is the right word - from AIDS. Sure, "stealing from the rich" isn't particularly 'fair', but "giving to the poor" sometimes makes it a necessary trade-off.

    58. Re:Example? by tyse · · Score: 1

      Since when did Corporations get equal protection
      under the law?

      Since when did Corporations have rights at all?

      Why do people think Corporations deserve anything even approaching what a human deserves?

      Corporations are a legal shield against being sue. They are a paper construction. They exist for our good, not us for theirs!

    59. Re:Example? by mimbleton · · Score: 1

      What if these "rich people" will decide to go to Brasil since their drugs are 20 times cheaper ?

    60. Re:Example? by Anonymous Coward · · Score: 0
      Yes, let's dump a task with the potential for massive financial gain or loss squarely on the shoulders of the academic researchers we depend on to serve as unbiased and objective observers of commercial science.

      Sounds like what happened when the Internet bubble burst.

    61. Re:Example? by lalas · · Score: 2
      I am told by a friend of mine who works for selling drugs to doctors that appoximately 70% of the cost of the drug is marketing expenses.


      While that is true, it is only true for the small number of drugs that actually get LAUNCHED. The vast majority of the drugs developed never make a dime for the company. Add the fact that a drug may be in development for 15 years before it is DROPPED and you have a situation where marketing the drugs that make it is extremely important.

    62. Re:Example? by Anonymous Coward · · Score: 0
      So you know how software prices go up and up in a pre-emptive attempt to recover costs from piracy? Ditto for tapes, CDs and DVDs?

      Is there a similar situation in the pharmacutical market?

      Umm, yeah, but they don't really have to bother with raising prices. They could just have it written off on their IRS forms.

    63. Re:Example? by lalas · · Score: 2

      Drugs are also patented many years before they are launched, so the window of patent protection overlaps the development process. You don't get patent protection from the day the FDA gives the 'thumbs up'.

    64. Re:Example? by Anonymous Coward · · Score: 0
      Countries that can club together to fund necessary research will thrive, (and so will everyone else of course). The EU is easily big enough to do this. The ones with a national health service will save a fortune on non-patented drugs.

      How laughable! What makes you think the EU could do a better job than private industry?

      Of course the possibliities of graft, corruption and fiscal inefficiencies that come with goverment enterprises are very seductive.

      Can you imagine how big this could be? You'd have the drug companies dropping reseach quicker than lead balloons, which would force a huge increase in govt involvement, which would lead to even more chances to 'work' the system. of course, there'd also be a huge tax increases to cover the costs, but that's no big deal, Europeans don't mind taxes. Seriously, they don't!

    65. Re:Example? by Anonymous Coward · · Score: 0

      > Screwing the companies that fund research is a bad solution to what is at heart a political
      > problem.

      The question is, would these countries be able to pay anyway?

      The article suggests that Brazil already came to an agreement with other drug companies, it just happened to be the one particular company that wouldn't lower prices.

      The drug companies should be happy enough to keep selling at current prices in countries where they actually get paid, like the US.

    66. Re:Example? by spiro_killglance · · Score: 1

      There Medicare/ Insurance Company / or Goverment
      would then not pay for it.


      Only a very few people pay for they own drugs.

    67. Re:Example? by Anonymous Coward · · Score: 0
      or turn over pharmaceutical research duties to Universities. That way the Uni's can peruse research that leads to *HEALHTY PEOPLE* and not to simple economic-profit.

      Ummm... yeahh... right. Like I want the govt deciding which diseases get funding to find cures. Oh, I forgot, they could just search for _all_ cures for _everything_.
    68. Re:Example? by 5KVGhost · · Score: 1
      I might agree with it, too, were it not for the fact that much of the R&D that makes these drugs possible is done with public money. Massive amounts of medical research (for AIDS, cancer, and lots of other medical conditions) are done at universities or other centers of learning, funded largely by grants from the government or other sources of income. The drug companies step in (or are called in) when it looks like they have something marketable or patentable.


      So the question is not whether medical research will continue if drug patents are loosened. The question is whether a drug company will continue to make exclusive profits from research that they did not conduct and to which we all contributed. I don't see any reason why they should.

    69. Re:Example? by krlynch · · Score: 2

      Sure, "stealing from the rich" isn't particularly 'fair', but "giving to the poor" sometimes makes it a necessary trade-off.

      Sometimes, it does; taxation for example - you make more, you owe more. But the question I don't see people asking or answering is: does stealing the IP of the pharmaceutical companies really equate to "stealing from the rich to help the poor". I don't know that it is (and I don't know that it isn't).

      Who is more likely to get hurt if the pharma profits begin to fall? Is the company going to lay off the top management, or the low paid schmoe in shipping? Does HIS suffering count less than the suffering of the AIDS patient? And what of his family? What about the large charitable donations made by these large companies? Which way will those go when profits fall? I haven't seen anyone doing a comprehensive analysis of who actually gets hurt in the end. Will new drug production really go down? It certainly won't go up, but it might stay the same. Will providing these drugs cheaply actually make any difference over no drugs? Or, like in South Africa, will the people who are getting these cheap drugs have so many other problems related to poverty that the drugs will do more harm than good? Will the loss of patent protection lead to more use of "trade secret" approaches, hence less long term dissemination of the information? Will this change the way other industries view the countries that ignore patents? Patents often describe the method of producing subparts of things (like the active ingredient), but trade secrets can be used to cover critical details of the production environment (such as the mixture of inactive ingredients necessary to stabilize the drug for storage). If THOSE details are become hidden rather than patented, the ability to make generics may evaporate. Do you want THAT outcome? There are a whole host of issues that are not being addressed frankly in this discussion, and it is kind of sad, because the really important issues are being clouded by the rhetorical debate over whether the drug companies are evil or not for charging for their products.

      If you take the cynical stance (and I'm not saying that YOU in particular do, but the general you) that the drug companies are ONLY in the drug business for profit, then you have to apply the same logic and conclude that the Brazilian government is ONLY doing this for political gain; claiming that "first world == evil intent" and "third world == good intent" is somewhat more than totally moronic. Personally, I'm convinced that reality is somewhere in between, the whole picture isn't being presented objectively, and no one has actually looked at the whole equation to determine if this is a net social "win", or if the short and long term consequences will turn out to be a net "loss".

    70. Re:Example? by Anonymous Coward · · Score: 0
      Just because software patents are patents on math & therefore stupid doesn't mean all patents are stupid.
      Says who?
      Drugs = patent on chemical combination. Software = patent on mathematical/algorithmic combination.
      Math is not trivial or common sense. Software is not always related to math. Nor are the patents on software. Math is not more "pure" or "common" than any other science, so why treat it as such?

      You are letting your emotions (people dying) get in the way of rational thought.
      Pharaceutical R&D is intensely expensive.
      And this is your basis for claiming specifically software patents are stupid? Please. So only certain people are allowed to make money now (i.e. people that spend buttloads of money, or rather those who have it to spend)?

      Obvious patents are stupid (which prior art should handle, but doesn't always). Non-trivial patents should be awarded to whoever gets there first.

      One fault of software patents is they are probably too general. They do not give specifics of how they implemented a certain algorithm and it is easy to step on other's feet accidentally. You should be allowed patents which use a similar algorithm of another patent, but changes a specific thing (to make it faster, efficient, etc.). This way patents are only good for specific implementations and not the modifications of that implementation.
    71. Re:Example? by Phil-14 · · Score: 1

      I have one thing to say: if you think we understand
      the human body, and the biochemical pathways,
      that well, you're vastly mistaken. Nuclear explosions
      are very easy to model in comparison to the human
      body. The first bomb was built in the '40's, but
      we have yet to "build" a human body.

      --
      (currently testing something about signatures here)
    72. Re:Example? by haruharaharu · · Score: 1

      As they derive from inalienable rights like the right to your own body, the right to property (property must be used to survive), and the right to deal with other people freely (right to your own body and their right to their own body), profits certainly are a *right*.



      How did this ever get marked as insightful?! Profits don't derive from those things, they derive from selling something for more than it costs. You have a right to attempt this, but no guarantee of success.

      --
      Reboot macht Frei.
    73. Re:Example? by dswan69 · · Score: 1

      Pharmaceutical companies spend at least twice as much on marketing as they do on research. Furthermore even these greedy bastards admit that they make almost all their money from first world countries - it won't hurt them one bit to be a bit charitable.

    74. Re:Example? by DrZZ · · Score: 1

      As others have pointed out, you are completely clueless. I do computer aided drug discovery and design for a living although nothing would be better for my career to have more dependence on computer modeling, nothing would be worse for the prospect of discovering useful drugs. We feel lucky to adequately model the interaction of one compound and one protein and you think it's straightforward to model the interaction of thousands of different modelcules with thousands of different proteins?

    75. Re:Example? by PinkStainlessTail · · Score: 1

      Yes, but this is AIDS. Among other things, AIDS is a highly visible "hot-button" disease. If Brazil was making their own generic Claratin for poor allergy sufferers, or Viagra, or a treatment for a less visible, less "popular" disease (chronic fatigue syndrome or lupus for instance), they would have gotten slapped down immediately. Or they wouldn't even have tried in the first place.

      I just don't see this gesture bringing about the end of the pharmeceutical industry.

      --
      "Slashdot is about legos and staplers." -Cmdr. Taco
    76. Re:Example? by MrDolby · · Score: 1

      The problem with this is what happens when those contries that are making their own supplies decide to start selling those drugs to the nations that have to pay for the patented versions.

      Sure the big evil corporate nations would not allow those drugs to be sold legally but an illegal drug trade is something that already exists, so I don't see much trouble in distribution of drugs that actually benefit the users.

    77. Re:Example? by tommck · · Score: 1
      All that aside, the company still manufactures the drug, don't they? They still have the brand name, don't they? Why is it a loss of money for them to have to compete with someone?

      SCENARIO:

      Company A puts $X (very large) into researching a drug.... discoveres a formula and then starts marketting it at $Y (with a pad in it to try to recover from X).

      Company B puts $0 (that's a zero) into researching a drug.... steals the formula from Company A... and then starts marketting the SAME drug at $Z (no need to pad for make up for zero investment).

      Company A will NEVER do this. Z is much less than Y! It will never be able to recoup the costs of the research.

      --
      ---- It puts the lotion on its skin or else it gets the hose again. It does this whenever it's told.
    78. Re:Example? by jafac · · Score: 2

      this is largely a recent trend, but a large portion of those marketing expenses are the "free samples" the doctor gives you when you visit with a problem.

      In fact, in this way, many doctors have become glorified drug hucksters.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    79. Re:Example? by jafac · · Score: 2

      the need for votes from people in the affected "high-risk groups"

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    80. Re:Example? by MrDolby · · Score: 1

      Your post is very interesting and you make some serious claims. Please provide some evidence or at least a real example of an instance of this occuring.

      Extraordinary claims require extraordinary evidence. -Carl Sagan

    81. Re:Example? by jafac · · Score: 2

      don't forget that this has the additional impact on the "generic" drug producers, who have retooled production in anticpation of producing their drug, on slimmer profit margins, with much less production experience. This eats into THEIR bottom lines as well, (pulling the rug out from under them with a patent-extension lawsuit) - and discourages the timely introduction of new expired-patent drugs into the marketplace.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    82. Re:Example? by jd · · Score: 2
      Yes, I do. If it were an exponential problem, as you seem to suggest, then it's still a computable one, it just requires a larger cluster.


      In practice, the problem is NOT one of difficulty. I don't care if you're dealing with one compound or a million - since you're going through them, solving the minimum energy equations, the number is just that. A number.


      One itteration or one billion, the contents of that itteration don't change. Complexity is NOT proportional to scale.


      Now, let's move on to the "understanding" of the human body. Excuse me, but who says you HAVE to understand it??? At any given instant, you can only ever have an interaction between two molecules. (DUH!)


      Since you're only ever dealing with a pair of molecules, the computations are trivial. These "interactions" you're going on about just don't exist, because you're dealing with radically different scales.


      In fact, I strongly suspect that that's been the problem with "protein/compound" simulations all along. You're trying to calculate the effect of an ant on an elephant, by looking at the whole elephant. Sorry, but the only thing affected by that ant is the immediate proximity of that ant. If you're computing anything else, you're wasting computer time. Oh, and my time, by me having to point out the bloody obvious.


      In the worst case, though, you're talking a thousand times a thousand - one million potential interactions. Or, if you prefer:


      for (i = 0; i
      Given that a =SINGLE= computer can handle billions of operations a second, exactly how long is it going to take to do a minimum energy computation?

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    83. Re:Example? by jd · · Score: 2
      We don't need to. We know every element on the periodic table (surprise! :), we know the valency of those elements, and we know the types of structures that are formed, and how to compute the energies of the bonds in those structures.


      From that, we have everything we need, to calculate how a compound will affect the body. Why? Because the compound -doesn't- affect "the body". The compound can only affect other elements and compounds.


      By simulating at the molecular level, we can forget about the body -and- all the biochemical pathways within it. We just need to know the initial conditions, well enough that the simulation is still within a reasonable margin of error by the time the compound has traversed the body.


      (I believe any given molecule circulates the entire system in a few seconds. Sure, you want a small step-size, but you're well within safety margins for even a crude model.)

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    84. Re:Example? by jd · · Score: 2
      Since the reactions you are interested in are at the level of bonds, you're really only dealing with AT MOST four atoms at a time. (Two from each molecule.)


      Further, since you're dealing with a large number of molecules, you parallelize across molecules, not across a single transaction.


      After reading all the replies to my post, I seriously wonder if I'm the only one who ever passed a course in parallel computer architectures. Each and every reply is trying to mix scales, parallelize at the calculations level, and examine the body as a whole.


      You can't mix scales like that. Mixing drinks is one thing (but still not a good idea), but mixing scales is a recipe for disaster.

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    85. Re:Example? by Hard_Code · · Score: 1

      If those drugs can't reach the patients what good are they?

      --

      It's 10 PM. Do you know if you're un-American?
    86. Re:Example? by gorilla · · Score: 2
      No, you're giving an example of a generic drug, where the same drug is manufactured and sold by multiple manufaturers under different names. A copycat, or a me-to, drug is where a drug company sees a competitor making a successful drug, and makes a drug with a similar effect. For example, prosac was the first SSRI. Since Prosac came out, other SSRIs have come out, such as Celexa and Paxil. However, a copycat drug isn't neccessarily less safe or safer. Sometime the me-to has safer sideeffects, sometimes not.

      The brazilian drugs will be generics, exactly the same as the patented versions, but not produced under license.

    87. Re:Example? by kalifa · · Score: 2

      > I don't think that companies should be deprived
      > of their right to complain about theft simply
      > because they advertise their products. That
      > doesn't make any sense.

      Of course, if you use this formulation, this does not make sense, but formulating the problem this way is already cheating: the line of defense of these companies is that, if 3rd world countries are allowed to produce low-cost, life-saving generic drugs, these companies won't have the money to make their research. If these companies were a little more honest, they would reckon that they would have the ability to cut enormous costs in order to favor research spending, if research spending were their true priority.

      The main consequence of money spent on marketing, in the wider sense (that is, not just "advertising", but lobbying, corruption, press, etc.) is not more efficient research and better drugs, but overconsumption and strong-arm tactics against smaller, better competitors.

    88. Re:Example? by khyron664 · · Score: 1

      I have a feeling I'm going to get flamed badly for this, but I agree to some extent. While most everyone who has responded to this is carrying on about how the company is making so much money, I think this is almost a thinning of the herd so to speak. How many YEARS have we known about AIDS? How many YEARS have countries preached against spreading it and how to avoid doing so? If people aren't intelligent enough to take the appropriate actions, why should we save their lives? Why go through all of this arguing because people are too stupid or immature to take responsibility for their actions? It's not like this isn't known to these people. If it's still spreading, that's the people's fault and they should take responsibility. I'm not one who enjoys hearing about a person's death, but where do we draw the line? At some point, we need to stop trying to save every stupid person and let natural selection take it's course. This is not a cold that you get accidentally, it's something you can avoid.

      Now, I will be the first to admit there are extrenuating circumstances to all rules, even this one. A blood transfusion (or even simplier things) can give a person AIDS, but if things like this were the sole cause of the spread of AIDS, you'd think the rate would be decreasing. It's a horrible disease to have, and I find it hard to believe that people could be clueless about how to prevent it's spread.

      As always, I am not an expert in this area and welcome intelligent responses to this post. I can not for the life of me find a reason for AIDS to spread and be this bad except for people's own stupidity and lack of responsibility. So why save them?

      Khyron

    89. Re:Example? by Hard_Code · · Score: 2
      Here's a less dramatic scenario: the companies decide not to bother developing drugs that save the lives of lots of poor people, preferring the safety of products to help wealthy people live another two years.
      Which will free up pharmaceutical industries in other, poorer countries, to develop and sell these drugs at-cost to its own population. Yes, great.

      Look at the range of quality on Freshmeat. Is that what you want to find in the drugstore?
      If the option is not being able to afford sactioned Microsoft software ("proprietary drugs"), then yes, the benefit/cost ratio fits the bill. Lessee, would I rather 1) be doomed to die a slow miserable hopeless death because even if I worked the rest of my natural life I would not be able to afford the drugs I need, or 2) settle for a cheap and perhaps lower quality alternative. I think I'll take option 2 thank you.

      I paid $1200 or so for my computer, $40 for LinuxPPC and nothing for Qt, KDevelop and gcc. Do you you see a problem in your extrapolation that researchers will therefore be eager to drop $100 million out of their pockets for compound screening and clinical testing? (Hint: I code for free, but I damn well don't pay the $100,000 a year that my research costs...)
      Ok, you're taking my statement a little too literally. What I mean is that even if a given pharmaceutical fails because society deems that the benefit offered the those who cannot afford one of its products is greater than that of the profit attained by the pharmaceutical, I don't think that pharmaceutical research will just stop, and that humans will never ever do it. That's ridiculous. Brazil and India are *glad* to produce drugs at-cost for their own population. Certainly these researchers (or at least the companies or governments they work for) aren't making the megabucks that their US counterparts are. But they are still doing it? Why is that? Wouldn't they be disincentivized? Profit is not the only reason humans do things.
      --

      It's 10 PM. Do you know if you're un-American?
    90. Re:Example? by Stu+Charlton · · Score: 1

      "You also make the mistake of believing that there is such a thing as "Intellectual
      Property." There is not. Any examination of the nature of property and the nature of
      information such as ideas will reveal the truth. Brazil cannot steal what is unstealable.
      And if they choose not to grant any rights to the inventor, there is no external authority
      from which the inventor might gain those rights. "

      Property is a construct granted by a society. To suggest that IP doesn't exist is absurd -- those with power declare it to exist, so it does. If they lose the power, then IP might cease to exist, for a time.. as it has in the past with various popular movements. But it always came back...

      IP was also fought for by those who create value for the world, the ones who deserve the right to control the fruits of their labour. Why? Because we've deliberated over these laws and ideas for centuries, and digital technology doesn't change the fact that APPLIED KNOWLEDGE IS SCARCE enough to require a property system to protect it to promote economic gain, so those with that meet the world's demand get the most economic resources.

      You can pray for nanotechnology, for global civil war, for the rise of the proletariat, or whatever -- but it won't change the fact that production of valuable IP is the new world scarcity, and it should be the decision of the individual creator as to whether he wants to FREE his work or whether he wants to exercise protection against duplication for a limited period of time. Or you're going to lose the benefit of people doing such work - they'll move on to other areas that are more economically sound.

      And the world society, (i.e. the WIPO, or WTO, for instance) will certainly attempt to ensure that IP rights are respected internationally.

      --
      -Stu
    91. Re:Example? by Anonymous Coward · · Score: 0

      nor would it hurt YOU to be!

      how much money have YOU sent in?

      YOU STUPID BASTARD!

    92. Re:Example? by Christianfreak · · Score: 2

      I agree with you except that unfortunatly in the United States the drug companies spend more money on advertising than on research.

    93. Re:Example? by eggz128 · · Score: 1

      Now, let's move on to the "understanding" of the human body. Excuse me, but who says you HAVE to understand it???

      I should hope that if your going to have a go at combating AIDs then you'ld have a damn good understanding of the haman body. After all, as a Virus it does hijack a lot of the native human machinery to do its job.

      Its very simple to combat AIDs, whats trickier is combating it and keeping the patient alive.

      At any given instant, you can only ever have an interaction between two molecules. (DUH!)

      Hardly. Anothing thing about human machinery is it's very rarely just one molecule interacting at a time, rather a number of subunits. If A couples to B which couples to C, and you have drug D, it's interaction with subunit C may cause A to go off and begin a potentially leathal cascade somewhere else.

      Now, inorder to do your minimum energy computations you'll need to know the structures of each subunit, and the solvent conditions they are in (probably water, but who knows, they could exist in the lipid bilayers). The PDB is good, but its no where near having all the structures present in the human body. You arnt just dealing with chemical bonds either, there are weaker interactions like Hydrogen bonds to consider. These are trickier to calculate.

      And then, maybe your drug (assuming its any good) may never even make it to the target sites. Maybe its not lipid soluble (and so cant get inside the cell), or acid labile (cant be swallowed).

      You see, you've tried to over simplify things to the point that your pissing in the wind. In many cases, you really are looking at the ant seriously affecting the elephant, maybe indirectly by affecting the mouse (say bacteria).

      That said, rational drug design has worked (IIRC even in designing a few nucliotide analogues used to combat the HIV virus). But the people in sat infront of the computers understand that it's more than a question of crunching numbers. As my Bioinformatics lecturer once said "Biology is a knowledge based disciplin, you work from what youve seen before. Physics/computing is ultimately easier, because you can work from first principles". We just dont know anywhere near enough of Biologies first principles to even think of moving completely to rational drug design.

    94. Re:Example? by Anonymous Coward · · Score: 0

      For now...but what if all countries did this on all "important" drugs?...

      What happens is, all those people taking the "unimportant" patented drugs will pay a lot more for them. This also applies to the "important" drugs in countries who take the responsibility to live up to their commitments.

      Brasil is doing nothing less than looting.

      -Peris

    95. Re:Example? by Anonymous Coward · · Score: 0

      If adults go around spreading AIDS, I don't feel sorry for them. I *do* feel sorry for the kids they bring into the world with AIDS though. This is probably a huge problem in a few countries that don't even have protection.

      I don't have a problem if 3rd world countries in desperate need get ahold of the drug "illegally," but it will eventually get smuggled back to the US, etc. and cause a problem for the companies which hold the patent.

    96. Re:Example? by Anonymous Coward · · Score: 0

      Man, you are very shortsighted. Do you know what is the salary of the people making all that "made in china" equipment you buy for hundreds of dollars????!!?!?!

      By buying that "cheap" stuff you are paying a huge racket to USA/Europe goverments.

      I completely agree that patents should not be recognized when one country needs to choose between life and death. Brazil probably paid more than whole R&D for that drug already...

    97. Re:Example? by Banjonardo · · Score: 1
      UD.com, provided by the University of Oxford, lets you download "tasks," complete them on free memory, and send them back.

      All this to help cancer research.

      Check it out.

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

    98. Re:Example? by DrZZ · · Score: 1

      Take a course in quantum mechanics and then you might be able to make sensible statements.

    99. Re:Example? by Phil-14 · · Score: 1
      I believe any given molecule circulates the entire system in a few seconds.)

      Actually, this is such a vast oversimplification it isn't even funny. At _that_ level of simulation, you're talking about some 10 to the 28 power particles.
      Assuming each particle takes a byte to simulate (and
      I'm being generous) it would take some 10^19
      _gigabytes_ of ram to store state information for them all. And I'm
      not even going to guess how much interaction cross-referencing will need to be done when you actually run
      the simulation.


      Slashdot has way too many people who think they have the answer to everything just because they can write spaghetti code in an obfucated language like Perl. I think the post I'm responding to is a perfect example. (Actually, I'm probably off by a factor of ten, by neglecting atoms that aren't hydrogen, but hydrogen accounts for more than half the discrete atoms in the body, so it's not far off. It'll do for estimating the amount of memory to within an order of magnitude.

      --
      (currently testing something about signatures here)
    100. Re:Example? by DrZZ · · Score: 1

      I don't which is more laughable; having a completely uninformed clown posting drivel or a completely uninformed moderator saying to himself
      "yeah, this makes sense".

    101. Re:Example? by Anonymous Coward · · Score: 0

      You know it brother. Fuck Africa. They need to get their house in order before we start bailing their sorry asses out.

    102. Re:Example? by jd · · Score: 2
      Multiple interactions cannot be simultaneous (simultaneous events are forbidden by GR), so it really still resolves to single reactions.


      A protein is simply a chain of amino acids, which in turn is simply a chain of bases, of which there are four (well, five, but the fifth isn't usually counted).


      Taking your example of A coupling to B, coupling to C, making drug D, you start by reversing the logic. D is made up of [A + B] + C, where A, B and C are sub-units which can be modelled inter-dependently.


      (It's not "independently", because they're connected, but it's not "dependent", either, because you can start at any point in that series. The calculations will still be valid.)


      Yes, you need to know the structure of each sub-unit. Indeed, this is entirely the point. You =WANT= to model at the smallest possible scale, because that will be the simplest scale.


      Now, it's perfectly true that we don't have the information required to model every cell in the human body at the atomic level (which is where you need to be, to do this kind of work). Here, you need to cheat. You pick initial conditions which are "about right", and run the simulation of the system minus the chemical you wish to introduce.


      Some initial conditions will be invalid, and the system will collapse. Others will work. This is very similar to that ecological game "foxes and rabbits", trying to pick conditions which work.


      In reality, there are several trillion variables you need to experiment with, and you're never going to pick a set that works "perfectly" within the lifetime of the Universe. In truth, though, you're not building this model to last a human lifetime. You don't even care about the drug's lifetime, really. You care for one cycle.


      Just one cycle? But how do you measure the cumulative effect?


      In truth, you don't have to. The cumulative effect is just that. The sum of the effects. Once you know one itteration, you can compute directly all itterations, through standard numerical methods. Ideally, though, you really want four or five cycles. About a minute of simulated time.


      How?


      This is slightly trickier. You take the simulation at time delta_t, for the model, and the model plus the drug you're testing. You compute the difference between these models. The basic calculation is as follows:


      State at time T(n) = State at time T(0) + Cumulative Difference(n)


      Cumulative Difference(n) = (Difference(0) / 2^n) + (Difference of Difference(0) / 2(n-1)) + ....


      In other words, each time round, the quantity left in the bloodstream will displace the system PLUS the residue of the displacement from the previous cycle PLUS the residue of the displacement from the previous plus one cycle PLUS the displacement from the displacement from the previous plus one cycle by the previous cycle, etc, etc, etc.


      It gets kinda complex, in writing, but it's really nothing more than a series, where the difference between any given two elements in that series is a function of every element prior (and therefore also every gap prior).


      The reason you really want more than one cycle is that every cycle you compute gives you an extra level of difference. In terms of calculus, one cycle gives you a first order difference equation. Two cycles gives you a second order, and so on. In truth, if you need more than a fifth order equation to get reasonable results, you've got problems.


      What we are generating, here, is essentially a trillion or so fifth-order difference equations, to model the effect of a drug, over a practical timespan. (One ATOM, one equation.)


      Because we're using difference equations, we're only dealing with simple addition and subtraction. This means that a trillion equations (which would be HORRIBLE if done as a detailed set of energy equations) reduces to a trillion times five sets of additions, which can all be done as very very long integers.


      Five trillion additions. That's ten trillion clock cycles. Divide by two billion, for a single processor, that gives you five thousand seconds, or just under 1.4 hours. On a single CPU.


      The idea of looking at a unified scale is to remove the problems of having things at different scales. Let's take the problem of "is it lipid soluble?" Well, you just don't care. Not at the atomic level. The interaction between entity A and entity B will -emulate- the solubility of entity A, with respect to entity B, even if you never have a specific "check" for that, or even know what to "check" for.


      A parallel to this is in arcade games. Entity A either "collides" with Entity B, or it doesn't. If it does, the collision detector fires that event, and the event handler then decides what action to take. But you don't need an event handler for every single entity in the game - most games would never finish checking, before they'd have to start the next round of checks, if you did it that way!


      Rather, you rely on low-level event detectors and event-handlers to eliminate detail and create an abstract solution.


      In the same way, you can simulate every chemical that exists, or ever could exist, by simply modelling every possible bond and every possible element. You have a set of "event handlers" for each bond and each element, then simply link your model to those abstract handlers.


      Take lithium salts, for example. A nice, easy one. You run your simulation, and find that there is a displacement in the model, everywhere that salt ratios are a factor. You also find that there's a displacement in various segments of the brain.


      But once the body reaches homeostasis, with the new salt, most of those effects go away. The body simply excretes excess salt, until the net levels are back to where they should be. What happens is that you achieve a new ratio, at the molecular level, although the system as a whole is largely unaffected.


      (Largely. It has some interesting affects on the brain. On the one hand, it is a "mood stabilizer" - in other words, it suppresses the extremes the moods will reach, it will also increase the probability of seizures. Even people who wouldn't normally get them have an increased risk.)


      Now, none of this can be discovered by testing animals. You can't really ask a rabbit if it's happy. And running an EEG on lab rats is unlikely to pick up whether human temporal lobes are likely to become less stable.


      On the other hand, a difference equation will show these things up. How? Because you'll have virtually no differences for much of the brain, but you'll have "hot spots", where the Lithium is having a profound effect.


      You won't necessarily be able to determine what those "hot spots" signify, but you WILL know that they signify something. Likewise, you'll know that the lack of a "hot spot" signifies that there is no displacement of the system outside what you might get anyway.

      --
      It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    103. Re:Example? by Anonymous Coward · · Score: 0

      a significant amount of that research cost in many cases is publicly funded

      But how many publicly funded treatments have come out of that research?

    104. Re:Example? by Anonymous Coward · · Score: 0

      Profits are not a *right*

      Drugs are not a right either. Especially drugs that won't get developed in the first place because the drug producers realize they won't get paid for them.

    105. Re:Example? by cpt+kangarooski · · Score: 1

      Well, regardless of the right of property being a societal construct, even it does not extend to the realm of information as in copyrights and patents. For if they did, why is it that so many human cultures could develop notions of property, independently and millenia ago, but it took until the 18th century for there to be any real laws we'd recognize with regards to copyrights and patents to start to come about, and many more years before they were widely adopted?

      I rather doubt that the people who first promulgated such laws had woken up one day and suddenly realized that everyone, everywhere, was infringing on others' property rights without a care in the world.

      To my knowledge, there is a three part test to determine if something is property. First, the alleged owner has to be able to enjoy the use of it; Second, they have to be able to permit or prevent others from enjoying the use of it at will; Third, they have to be able to dispose of it at will.

      Copyrightable content and patentable inventions fail the second and third tests due entirely to their nature. In order for human beings to understand or be aware of an idea, the idea itself must be made available to them, but it is impossible to dispose of it. For example, if I describe to you my invention for a widget, or read to you from my book, I can not compel you, and you can probably not cause yourself, to forget it on command.

      Nor can I do the same myself, even if I attempted to sell it to someone else, promising to divest myself of any copies.

      Therefore, copyrights and patents, at least in the US (as previously mentioned) are not founded in property law. (if they were, they'd not warrant mention in the Constitution, for starters) They're founded in absolutely nothing, in fact, but are just considered something that Congress may or may not choose to permit to exist here. (with certain constraints, the presence of which without conflict with eminent domain, again clearly shows their nature as non-properties)

      The confusion comes about for, I believe, two reasons. 1) Copyrights and patents are property. No, I'm not contradicting myself. The copyrighted _content_ or patented _invention_ are not property, but the rights optionally granted an author or inventor by the government (if it desires to do so) may be treated as intangible property. 2) Copyrights and patent rights are not rights, but are really the infringement - temporarily - of rights for virtually all of the populace. This infringement ceases when the term expires, and everyone can again enjoy the use of the work or invention as though it were never copyrighted or patented, and without governmental intervention as is needed to maintain the infringement.

      The natural state of information is one of freedom, and it tends towards this (the quote "Information wants to be free" is not a demand, it is an anthropomorphization, rather like "Water seeks its own level." It describes what information usually does in the absence of a counteracting force.)

      No one, however, deserves the right to the fruits of their labors so long as we're discussing copyrights or patents. They are a grant to an author or inventor, made by the government, at the direction of the public. And the government gets to set the terms, and acts only in its own (and its peoples at large) best interests. It is for this reason that you do not find in the US Constitution language to the effect of authors et al having natural rights or deserving rights to control these things. It instead justifies these structures as promoting the arts and sciences; a public benefit.

      (kind of like the public benefit in having secret bids for government contracts, very often. Sure, the contractor gets paid, but the public gets a good price)

      Additionally, written language is a digital technology, and publishers have always had problems with their competitors using the same methods and techniques to duplicate their efforts. There's little new under the sun.

      Your argument is bogus - if you can prove that authors or inventors deserve rights beyond what we're prepared in general to give them or take away at our pleasure, do so. No one has yet, AFAIK.

      I'm not advocating the abolishment of these systems, though I do advocate their reformation. But I don't delude myself as to their origins or purposes. Incidently, for a decade, just until a week or two ago, when I went back to school, I made my living as an artist. I have a decent idea where I'm coming from.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    106. Re:Example? by Anonymous Coward · · Score: 0

      Right on, the "it's profit vs lives" people have lived in a rich technological society so long they're forgetting what -made- the drugs that keep their parents alive until 70+ YO.
      Merck didn't discover Rymadil (whatever their new anti arthritis drug is) because "information wants to be free". They PAYED thousands of scientists living wages to MAKE it happen. Do those scientists deserve to work for no pay?
      I guess if you can't reach that far into abstraction, think about what's going to happen when -you're- 70, do you really think the big drug firms are going to say "oh, to heck with that filthy lucre stuff, will just enslave these scientists, steal the physical plant and crank out new pharmaceutical X" ?!
      This is seriously bad shit, it will impact YOUR life in a seriously negative way. Of course, we should find some way within the market system that both incentivizes R&D and provides expensive meds to low income populations (tho the Pharmacorps are already in legal trouble for charging less for the same thing in Canada as they do in the US).
      But this cuts off our future R&D despite our present needs. It's not even going to save those patients.

    107. Re:Example? by Anonymous Coward · · Score: 0

      And while R&D might be expensive, Big Pharma is still making coin hand over fist, and none of the drug companies are getting out of that industry because it is not financially viable

      The issue is that Roche (et.al.) want to charge more for a few doses of drugs than people in third world countries can expect to make in a year. This is clearly unacceptable.


      OK, maybe this is more acceptable - since Roche (et al) don't get paid for their goods, they quit developing and marketing drugs, close up their doors, and just say "To Hell with you".

    108. Re:Example? by Anonymous Coward · · Score: 0

      Wake up, death is the ONLY alternative. Generally an earlier one (treatment only makes it slightly less early) with HIV/AIDs.

    109. Re:Example? by Anonymous Coward · · Score: 0

      "Personally I would like a solution where rich contries payes more for drugs and poor ones less but it may be diffucult to implement in reality. "

      HELLO! This precisely describes the current market system. Both Kaiser permanente and medicare are talking about suing major pharmaceutical companies BECAUSE they charge less for drugs in countries with slower economies then the US (specifically, claritin in Canada is almost half the cost of claritin in the US. partly because the canadian OTC system is more reasonable, and makes more volume. But also because the producer decided to make less profit in that market because it's economy is slower then the one in the US).

    110. Re:Example? by the+gnat · · Score: 2

      Given that a =SINGLE= computer can handle billions of operations a second, exactly how long is it going to take to do a minimum energy computation?

      A long time. The programs CNS and XPlor are the standards for refinement of crystallographic data, and the insanse structural biologists at my university/work will have jobs running for weeks on multiproc Alphas.

      I suspect you have no clue what you're talking about, since you mixed up DNA and proteins in a later post, but you should actually try dealing with molecular dynamics, energy minimization, and structural biology before posting this garbage. Several points:

      - XPLOR and CNS do energy minimization on partially solved protein structures. There is still years of work required to get these structures.
      - Both programs are at least 100,000 lines of F77 code, without comments. I may be miscounting- I don't know Fortran (yet)- XPLOR looks a lot bigger.
      - Parallelization hasn't really caught on- but they've definitely tried. It's easier with something like genome mapping- we're buying a cluster just for parallel sequence alignment. Shared-memory MPPs will almost certainly be more effective.
      - Macromolecular simulations on known structures are still iffy. I'm starting to work with a database of simulations, and a large number are duds. This is for attempting to morph similar conformations- a far, far less intensive task than what you're proposing.
      - The above programs all use "energy minimization". You're talking about "molecular dynamics", which is much harder.
      - Many, many researchers are attempting to do exactly what you're talking about, and they're having about as much luck as you'd suspect. I'd imagine some of them are extremely capable programmers. Certainly they know quite a bit more biophysics than you do. This includes Big Pharma, by the way.
      - IBM thinks they can do this. They're building the world's most powerful computer just for the task. Few organizations can afford this.
      - You are vastly oversimplifying molecular dynamics with the ant/elephant bullshit. Modifications like glycosylation and helical packing may change structure quite a bit. Even if we could figure out the secondary structure correctly from amino acid sequences- which we can't with enough accuracy for real drug design- that doesn't tell how the loops turn and how the tertiary structure forms. It's not just a matter of local interactions- more like a hideously large backtracking algorithm, I'd say.
      - Mapping protein-protein interactions is a different matter; at any rate, it currently requires high-resoltion crystal structures and is still computationally intensive. I believe co-crystallization is preferred.

      [ disclaimer: I normally study genomics, and I'm still in college, so not everything I say is gospel. I do program though. Certainly none of this is as far off base as the drivel above. ]

    111. Re:Example? by Anonymous Coward · · Score: 0

      This is political. Take the former soviet union for example. They poured so little money into R&D and lost so many citizens to illness that has been cured elsewhere. I say give the money to the drug companies. If you dont, eventually the drug companies wont make such useful drugs, or if they do they will guard their formulae with such ferocity that you will have to leave the country just to get a dose of antibiotic X.

    112. Re:Example? by H310iSe · · Score: 1
      On this line of R&D -- part of the 'coctail' was developed by US national labs (NIH) and *given* to Eli (if I remember correctly) to distribute - the US govt. paid the full cost of development then gave the patent away. I'm sorry I can't find the link on this right now but I've been following this story for a while ... Eli bitched to high heaven when Brazil threatened to break their patent but eventually came to their senses. Huge props to Brazil who has reduced their AIDs population by HALF of the WHO estimates from a half decade ago. What a beautiful country... If only parts of Africa could follow their example.

      --
      closed minded is as closed minded does
    113. Re:Example? by eggz128 · · Score: 1
      Let me start by saying that I like your thinking, but I just cant see it as feasable in any way.

      A protein is simply a chain of amino acids, which in turn is simply a chain of bases, of which there are four (well, five, but the fifth isn't usually counted).

      A protein is simply a chain of amino acids, that may be modified by glycosolation (actually a major thing to consider), methylation, there may be disulphide bonds added (not really in any predictable position), the chains may be complexed with metals (eg haemoglobin), the protein may only be functional under certain conditions, it may be sequestered by other proteins, it may be free in solution, it may be contained within a lipid membrane...

      As for the bases, I presume you mean the DNA bases that encode a protein, i.e. Adenine Threonine Guanine and Cytosine, and the 5th you refer to is Uracil (replaces Threonine in RNA which is transcribed from DNA). To say that Uracil is mostly ignored is quite insulting to a graduate biochemist :) BTW, in real systems some of these bases may be methylated aswell.

      Taking your example of A coupling to B, coupling to C, making drug D, you start by reversing the logic. D is made up of [A + B] + C, where A, B and C are sub-units which can be modelled inter-dependently.

      I think you need to go back and read again. Its not A to B to C makes D, it's A coupled to B coupled to C makes a functional unit, which interacts with drug D.

      Add to that then that A and B, and maybe B and C have seemingly unrelated roles elsewhere. Then in cell type X you have another interacting partner F, which isnt present in your first cell type (for which you took the initial conditions). Introducing drug D to cell type X results in apoptosis (cell death), or worse, necrosis.

      How do you decide which (computationally) seemingly benificial reactions, are infact the road to death and general nastyness?

      Your previous statement that you only need to model at most 4 bonds (chemical) is also a fallacy. As I tried to allude to earlier, some of the most important bonds in biological systems are hydrogen bonds. Fuzzy bonds if you like. Singly they mean very little, but on mass they are major contributors of the three dimensional structure of proteins. Un my example, A B and C are linked by multiple hydrogen bond interactions. Your initial energy minimization may not even represent the way drug D interacts with these protein subunits. Believe it or not, the lowest possible energy does not always represent the wild type state of a protein.

      Given an amino acid sequence we cannot, even now, accurately define the three dimensional structure of a protein. Thats a single protein. Now how on earth do you propose to work out benificial or adverse affects of a single drug on an entire complex system?

      You cant even pick initial conditions that are "about right" because everyone is different. Even the conditions inside one individuals body varies incredibly over a few hours. Ever wondered why you can eat peanuts and they will kill another person? This is just the type of randomness you have to deal with. If you like, you may have subunits A B and C, someone else may have A B and G which perform the same tasks, but react entirely differently to Drug D.

      The idea of looking at a unified scale is to remove the problems of having things at different scales. Let's take the problem of "is it lipid soluble?" Well, you just don't care. Not at the atomic level. The interaction between entity A and entity B will -emulate- the solubility of entity A, with respect to entity B, even if you never have a specific "check" for that, or even know what to "check" for.

      I'm afraid I'd care quite a bit if you came up with a wonder drug that could never reach it's target. A cell isn't just one lipid bag, it has many little bags inside it. If your drug cant reach it's target inside one of these bags it's rather a waste of time, if it reaches and adversly affects a different system, then it's a liability.

      But once the body reaches homeostasis

      Another quote from a lecture, "the only time reactions reach homeostasis in the body is when you are dead". Really you'ld need a good book on metabolism to understand that, but theres always something driving a reaction.

      Animal testing isnt really about finding drugs, it's about finding how harmful and/or effective they are on an entire biological system, before moving onto a human system. As I said, Biology is a knowledge based disiplin. Does it kill the rat? No? Well lets try it on something else. Oh, and you may be suprised just how much we have in common with rats and mice.

      Your proposed methods of drug design would be wonderful, if it were not for the fact that there are just too many unknowns for it to be viable (at least in the forseeable future)

      I would however encourage you to think about studying biochemistry. With a real understanding of the difficulties behind drug design, maybe one day you may be able to ratianally design an aids cure.

      Maybe.

    114. Re:Example? by Anonymous Coward · · Score: 0

      &gt Thanks to the widow of Jerry Henderson for reporting this.

      Dude! that is probably the funniest thing I think I've ever read on slashdot! You made my day!

    115. Re:Example? by Malcontent · · Score: 2

      They can already go to canada and mexico where drugs are vastly cheaper. The american suckers (I mean consumers) pretty much pay twice. Once when vast amounts of tax payers mones goes to R&D and then again when they subsidize the lower cost of drugs in other countries.

      --

      War is necrophilia.

    116. Re:Example? by aprentic · · Score: 1

      Yes pharmaceutical research is intensly expensive
      but most of the cost is not born by the pharmaceutical companies. Government grants pay for large portions of the research. This money comes from taxpayes who shouldn't be double charged for a product.

    117. Re:Example? by Anonymous Coward · · Score: 0

      USA did it after independence. I think China did it 'till recently.

    118. Re:Example? by achurch · · Score: 2

      ...but what if all countries did this on all "important" drugs? Drug development is massively slowed, and the deaths start mounting by the millions because of slowly advancing technology -- people who wouldn't have died had technology kept advancing at a good pace.

      But what if all countries respected all of the patents? Drug supply is massively restricted, and the deaths start moutning by the millions because of greedy corporations -- people who wouldn't have died had the countries been able to produce the medicines themselves.

    119. Re:Example? by axxter · · Score: 1

      Well we recently passed similar legislation to Brazil's here in South Africa, ours alows the government to licence and import generic anti-retrovirals.

      One of the interesting facts to emerge from the debates was that on average only 4% of a drugs price was in R&D, the rest was marketing, pakaging and other overheads. What has hapened here is that many of the manufacturers of anti-retroviral drugs have started matching the price of the cheaper generic drugs

    120. Re:Example? by Anonymous Coward · · Score: 0

      I'm sorry, but (not to be mean) there is NO cure for aids. The least this will do is erode any further hope for an AIDS cure. Sure, human life is at stake here, but god, is this going to save any of those lives? NO.

      The current AIDS medicines relieve symptoms, prolong life, and (the profit) contributes to further research.

      How the hell is this going to end the AIDS problem? It won't... it will impede any research

      prolixity

    121. Re:Example? by Anonymous Coward · · Score: 0

      I don't think the universities could afford the burden of developing EVERY investigational new drug.. unless of course, they patented the product.

      Moron.

      You want more medicine or less?

    122. Re:Example? by Anonymous Coward · · Score: 0

      therefore you have nothing worthwhile to bring to this thread.

      Why don't you double check your sources- The BDI research on that subject was proven flawed more than a month ago. They didn't take many costs into account.

    123. Re:Example? by Anonymous Coward · · Score: 0

      Other overheads, such as manufacturing, purchase of raw materials (example: clonidine costs over $10,000 a gram), labor, training, GMP compliance, GLP compliance, any other regs they have to follow such as 40 CFR, facilities, employee benefits, etc? It doesn't cost ten dollars to make a million systems, moron.

      Did you know that it costs at least $450 million to set up a small pharm plant?

      DEA licenses,

    124. Re:Example? by Peter+Harris · · Score: 1

      Cynicism apart (and I have to agree that I don't trust any particular government to do anything properly), there is no reason why not.

      Note #1: The EU (for example) don't have to "do a better job than private industry". They just have to fund the research. Private industry would do the research, for profit. They just wouldn't "own" the results.

      Note #2: At the moment, pharmaceutical companies spend millions on research that might never result in a successful product. They take a gamble with each new drug. Why would they "drop research" when it would have become a *more reliable* source of income?

      Note #3: A fucking huge amount of tax ends up being spent on expensive patented medical technology anyway. The money that allegedly provides the only incentive for pharmaceutical research doesn't just appear from nowhere.

      Here's a question for you - is it wiser to spend the money once and get the results cheaply for ever or let someone else own the research and pay a monopoly-controlled high price for at least the next 17 years?

      I mind my taxes being spent unwisely just as much as you do. I just think public research for the public domain is better value for money than lining the pockets of a few giant corporations.

      --

      -- What do you need?
      -- Gnus. Lots of Gnus.
    125. Re:Example? by NoOneInParticular · · Score: 1

      As always, I am not an expert in this area and welcome intelligent responses to this post. I can not for the life of me find a reason for AIDS to spread and be this bad except for people's own stupidity and lack of responsibility. So why save them?

      To add my own clueless answers to this kilothread, the reason for saving these stupid people as you call them is simply because letting them all die will destroy their society as a whole --- thus including the smart ones.

      Take a few African countries as an example: estimates about HIV-infection hover between 25 and 30% of the sexually active population (sorry, no link). Sexually active people grossly fall in the age group 15-40 years of age. This is exactly the age group that keeps a society running. If one in four of every teacher, doctor, factory worker and farmer dies, any country will get disrupted. For African countries, given the poor state they are in already, this will mean that their education system will collapse, their medical system will die, export will collapse etc. Then the 'smart' part of the population will suffer as well.

      Look around you and imagine that one in four of the people at work anywhere are no longer there. Do you think your standard of living will be unaffected by that?

      I don't know the exact figures in Brazil (heard a number of 200K at the BBC yesterday), but I can imagine that they do not want to lose a significant part of their productive population because some company somewhere decides that those can't afford to survive. If a country's survival is at stake, international law ceases to be relevant.

    126. Re:Example? by Bobo+the+Space+Chimp · · Score: 1

      > Drug supply is massively restricted, and the
      > deaths start moutning by the millions because of
      > greedy corporations

      This, my friends, is the Socialist Shortsighted Fallacy (for lack of a better term.)

      If I want to get rich, and cure cancer tomorrow, and charge $10,000 per cure, I'm somehow evil (!) Yet I have cured cancer.

      If I am prevented from doing this (why bother? No profits...) then there is no cure for cancer.

      ...and people continue to die by the millions, content that they are not being "ripped off".
      History shows time and again that the former is always, always better than the latter.

      The number of deaths "caused" by this ficticious greedy corporationn (that Charles Dickens would no doubt love) are greatly exceeded by many, many orders of magnitude by the very real effects of socialism in slowing advancing technology.

      A world where greedy corporations "ripped off" people with their cures would, year after year, have far fewer deaths than those that prevent "ripoffs".

      That is the counter-intuitive truth of reality.

      --
      I am for the complete Trantorization of Earth.
    127. Re:Example? by rocca · · Score: 1

      Oh good, I was hoping my tax dollars would go to fund research on how to stop my dog from scratching his ass in public, after all no need to be financially responsible. Yay, corporate destruction, let the government do and pay for everything, but not control anything, laws are bad, patents are bad, let's all work for free, we'd all pay our fair share, no slackers, honest.

    128. Re:Example? by Anonymous Coward · · Score: 0
      The patent holder was GRANTED that patent by the US because it was
      felt that doing so would have a public benefit.


      Many of you seem to suffer from this misconception. Patent is granted so people only interested in profit would bother to invent new things. The "new things" are ment to create more capital and keep capitalism going. Some would call that public benefit, and some would not.

      On a planetray basis most would not.

    129. Re:Example? by cpt+kangarooski · · Score: 1

      Well, again, this depends entirely on the rationale your particular locality has regarding patents.

      In the US (which I am most familiar with, whose utilitarian system I most prefer) patents are only granted in accordance with the intent of promoting the progress of the sciences. This is clearly a public benefit, though any private member of the public will benefit from it as well, and accomplishing this may take some interesting turns.

      It's not really intended to keep capitalism going - it's intended to improve the position humanity occupies. Capitalism is a potential tool, but the entire system is optional at any rate, and need not be implemented at all, or could be in a different manner whilst still remaining Constitutional.

      Again, I can't say much about the Brasilian patent system, so I've been avoiding talking about it, save for the generality that it is up to Brazil to decide how they will treat inventors; if the inventors are citizens of that nation, then they have no more substantial weight than any other citizen, and if foreign have no more than any other foreigner. Having invented something accords no special powers or rights on its own.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    130. Re:Example? by Stu+Charlton · · Score: 1

      I don't believe we're at actual disagreement here. I believe the global IP system should be reformed in certain ways; not abolished. Though I think I have a qualm with some of your premises, which are detailed below.

      - People developed notions of intellectual property in the 18th century because this was the first instance of when intellectual works could be wide spread due to the invention of the Gutenberg press. Before this time, only the elite few posessed (let alone read) written works.

      But with this mass duplication comes a societal responsibility to encourage the creation of works valuable to society. "ideas" are not property in the traditional sense, but certain manifestations of them are due a level of protection to economically promote those with talent to create such works.

      - Hence, the need for -some forms- of protection of creative works is historically difficult to dispute (the French Revolution's aftermath being an example, the constituation mentioning it being another example).

      - The "3 part test of property" is one definition of property, but such a test is not universal. A synonmous definition of property (according to Merriam-Webster) is that of a legal "title". Another definition is that of a contract for a performer who's work is valuable.

      - So, you're quite right that IP law is not based out of traditional law. Since IP is so diferent than regular property it has a whole different set of contraints, motivations, and purposes behind it. Most arguments against IP law set up the strawman that it "ought" to be based out of property law, and then set out to point out why it possibly can't be (which is obvious).

      - "Entitlement" is the basis upon which intellectual property rests. The major problem seen with IP law is one of terminological confusion.

      Intellectual property is a system of law that promotes a set of temporary economic protections for creative works. My argument (to my knowledge) never argued that intellectual property was a state of natural rights, so I fail to see why it's bogus.

      I stated that applied knowledge is the new world scarcity and all developed societies are willing and justified in promoting a system of protections to promote creative works.

      - "Information wants to be free" really implies "information wants to be duplicated", which does not defeat the notion of IP as I've outlined it above as a system of economic protection. Rather, it shows how copyright is inappropriate to the digital age with a negligable marginal cost for duplication. When duplication now primarily impedes consumers instead of competitors, there needs to be an alternative protection mechanism with similar intent.

      Fundamentally, the purpose of copyright is twofold, from my understanding: a) the ensurance of remuneration for the originator (author or primary investor) in the creative work, b) the granting of temporary monopoly so as to ensure that economic resources flow to the creator instead of speculative opportunists that add little value to the creative process (which is the real economic value).

      So the reformation of copyright will have to recognize that the creation of information is a service. Services are regulated under the realm of contract law. One has the right to render certain restructions under contract for the use of various services rendered -- which ties into the definition of property as "license" or "title".

      Now having stated that service providers have a right to "license" their works, I think it would be difficult to argue in favor of restriction on access and duplication such as what the current DMCA supports (though, unfortunately, the legal tide seems to be solidly on the side of the DMCA for now). It can be argued that all access and duplication is effectively "fair use" once someone has been "entitled" or "licensed" to use the intellectual work. But this is a concept that needs further expansion, as we would require a universal "license" system in this case to ensure remuneration -- and this in itself poses tremendous logistical problems, but it may be the only workable system , as it's much more realistic than attempting to enforce the unenforcable (and undesirable for society at large, once it recongizes it)

      So, to summarize, IP does exist -- it's not traditional property, such an argument is a strawman. It's a system of entitlement to ensure that economic value flows to those the market likes, thus promoting innovative creative works, and thus intellectual progress in specific areas of demand.

      (Britney Spears... mmmm.. progress... :)

      --
      -Stu
  5. Re:anal expulsive prick by Anonymous Coward · · Score: 0

    you misspelled 'siht' as 'sith'. jedi-freudian slip?

  6. Its about time... by tewwetruggur · · Score: 2
    I'm glad to see common sense and the common good win over so-called IP rights. Too bad Roche seems to have missed the boat for a great philanthropic opportunity.


    I hope that events such as this one will help some companies realize that there's more to business than just having a good IP portfolio.

    --
    Hi! This is the Sig, blatantly attached to the end of this comment.
    1. Re:Its about time... by Anonymous Coward · · Score: 0

      It will be interresting to see if you are equality glad when you get cancer and there are noone developing cancer drugs also.

  7. how about the need to protects patents?? by Anonymous Coward · · Score: 0
    i'm sorry, but brazil is clearly in the wrong here.

    What happened to the drug companies' rights?

    If they don't receive royalties on their drugs, how are they going to support ongoing research?? What is Brazil doing to cure AIDS??

    It looks like they just want to get something for nothing to me.

    1. Re:how about the need to protects patents?? by Kryptonomic · · Score: 2, Interesting
      (sarcasm)Awww... my heart bleeds for the pharma companies who have been ripping fat dividends for their shareholders forever.(/sarcasm)

      The Big Pharma can either put up or shut up. They had two options: negotiate reasonable drug prices with Brazil and still make profit or lose every chance for profit. Any self-respecting government will opt for patent infringement if it is a way to save the lives of their citizens.

      It will be a sad day indeed if and when the corporations become so big and so powerful that sovereign governments won't dare to tread on them if necessary.

    2. Re:how about the need to protects patents?? by Anonymous Coward · · Score: 1, Interesting

      What is Brazil doing to cure AIDS??

      They're having lots and lots of unprotected sex. If we let them continue at it, they'd kill off the entire population of people except those that are naturally immune to it. Unless they get medicine, which allows them to continue on business as usual, ignoring reality.

    3. Re:how about the need to protects patents?? by Alex+Belits · · Score: 2

      What happened to the drug companies' rights?


      Nothing. Companies are not people, they exist only because governments say so, and their "rights" are supposed to defined, as whatever benefits people.


      If they don't receive royalties on their drugs, how are they going to support ongoing research??


      They can cut spending on advertisement of their yet another 24-hours nasal decongestant by few percents. And, maybe later at least one of those Brazilian people, whose lives will be saved because of this, will do a piece of biological research that will be crucial for those pharmaceutical companies.


      What is Brazil doing to cure AIDS??


      Keeps its people alive.

      --
      Contrary to the popular belief, there indeed is no God.
    4. Re:how about the need to protects patents?? by DoubleTake · · Score: 2, Informative

      I'll bite.

      i'm sorry, but brazil is clearly in the wrong here.

      Not clear at all

      What happened to the drug companies' rights?

      Rights created and conferred by elected governments. The elected Brazilian government justifiably thinks that the tradeoff between corporate and people's rights is different in their country.

      If they don't receive royalties on their drugs, how are they going to support ongoing research??

      Drug companies do not have a right to the public's money to subsidise extraordinarily inefficient research programs. Most drug company income lines the pockets of executives and shareholders anyway.

      What is Brazil doing to cure AIDS??

      Probably alot more than most drug companies. The large drug companies have a consistent record of ignoring the third world because there's no monopoly profits to be made.

      It looks like they just want to get something for nothing to me.

      I'd say it's the companies who want something for nothing.

      It's unreasonable that an intellectual property creator should not be paid for their work. It is equally unreasonable, and for the same reasons, that an intellectual property creator should be paid an indefinitely large number of times for the one intellectual property.

    5. Re:how about the need to protects patents?? by gazbo · · Score: 1

      They can cut spending on advertisement of their yet another 24-hours nasal decongestant by few percents.

      Whilst I would love to think in such simplistic terms, I have to point out:
      If cutting spending on advertisments resulted in an increase in profit, why do you think they do spend that much? Surely you don't think they enjoy giving money away just for the sake of advertising?

      As somebody said earlier in the discussion, money has to change hands somewhere. If drugs should be available to poor countries for free, vote in a government who will increase taxes in order to pay for these countries to receive medication.

      I'm sure 90% of people would whole-heartedly agree with this idea, right up until a government actually suggested doing it...

    6. Re:how about the need to protects patents?? by Rudeboy777 · · Score: 1

      What is the U.S.A. doing to cure obesity, high cholesterol and heart disease??

      They're having lots and lots of cheeseburgers and french fries. If we let them continue at it, they'd kill off the entire population of people except those that are naturally immune to fast food. Unless they get triple bypass surgery, which allows them to continue on business as usual, ignoring reality.

      --

      From hell's heart I fstab at /dev/hdc

    7. Re:how about the need to protects patents?? by Anonymous Coward · · Score: 0
      sorry but the truth of the matter that nobody has any fundamental right to something produced by a private company for free. If you can't pay for it, negotiate a deal or develop it yourself.

      Most drug company income lines the pockets of executives and shareholders anyway.

      typical ad hominem attack. do you have any evidence for this or are you just talking out of your ass?

    8. Re:how about the need to protects patents?? by Alex+Belits · · Score: 2

      If cutting spending on advertisments resulted in an increase in profit, why do you think they do spend that much? Surely you don't think they enjoy giving money away just for the sake of advertising?


      Of course, it will decrease the profits! It just won't affect the development of useful drugs.


      As somebody said earlier in the discussion, money has to change hands somewhere. If drugs should be available to poor countries for free, vote in a government who will increase taxes in order to pay for these countries to receive medication.


      Money don't have to change hands -- government can just use their collective buying power to force companies to accept slightly lower profit margins, what will be healthy for both people and the economy. Don't forget that drug companies have obscenely high profit margins, and spent most of their time, money and effort on the development of expensive but nonessential products and incrementl enhancement of existing ones.

      --
      Contrary to the popular belief, there indeed is no God.
  8. Public Needs... by DJerman · · Score: 1, Troll

    Bravo for Brazil! Unfortunately (?) no-one's life is at stake over one-click ordering (or any of the other stupid algorithm and business method patents). It's unlikely this will have any impact on US/European patent law.

    --
  9. Bullshit. by FatSean · · Score: 2, Flamebait

    I sincerely doubt all the AIDS cases in Brazil were caused by blood transfusion, or passed from mother to child. A high percentage of those infected became that way by choices they made in regard to sexual activity and sharing of needles. In this age of education, AIDS is generally acquired do to ignoring precautions. Ignorance is no answer.

    --
    Blar.
    1. Re:Bullshit. by Jedi+Alec · · Score: 1

      In this age of education, AIDS is generally acquired do to ignoring precautions. Ignorance is no answer.

      I hate to kick you out of your Ivory Tower, but did you happen to notice that the level of education isn't equally high all around the world? Otoh, your post clearly demonstrates, so no point going into it any further. And aside from education, there is also this thing called religion, and unfortunately the dominant religion in Brasil is led by some sort of old guy who never had sex and who thinks rubbers are evil...
      --

      People replying to my sig annoy me. That's why I change it all the time.
    2. Re:Bullshit. by 1001011010110101 · · Score: 1

      Are you on acid or what?
      The reason why they infected is not important, unless you believe that bullshit that AIDS is "God Revenge" for sinfull acts.
      That doesn't change that international drug producers are milking as much as they can for a drug needed by many people to survive, many of which are in underdeveloped poor countries with little or no education on the subject.

    3. Re:Bullshit. by l33t+j03 · · Score: 0

      I hate to kick you in the face but did you happen to notice that this sentence containd no commas?

    4. Re:Bullshit. by Harbinjer · · Score: 1

      And if people listened to the other things this "old guy" says, there wouldn't be nearly as many cases of AIDS. The Catholic church is against pre-marital sex as well, so if people actually followed that at all, the only way to get AIDS is a blodd transfusion or some kind of bloody accident...

    5. Re:Bullshit. by why-is-it · · Score: 1

      A high percentage of those infected became that way by choices they made in regard to sexual activity and sharing of needles. In this age of education, AIDS is generally acquired do to ignoring precautions. Ignorance is no answer.

      Where the population is literate, educated and well-informed, this *might* be true. However, I would think that in the slums of Brazil where these conditions are not met, and the government of Brazil is correct in being more concerned about the health and welfare of their citizens than the profits of some multinational.

      --
      *** Where are we going? And what's with this handbasket?
    6. Re:Bullshit. by cybrthng · · Score: 1

      Then why doesn't the allmightly low and behold catholic church go to brazil and preach its ethics? Isn't religion supposed to be a foundation of life? If the catholic religion was the real basis for what you base your beliefs on then why doesn't everyone believe it?

      For the simple fact that you or your region aren't absolute. IF you want to make a difference it is something YOUR doing and not your religion. Go brazil, stop the epidemic! Teach your population and don't be a part of the tyranny of corporatism and absolute beliefs in religion.

      Old timer or not, if your "religion" can make a difference then why not DO SOMETHING about it. Atleast the mormons do something for brazilian families. I have yet to see catholics do anything besides complain.

      Hey, religion is kid, being a part of something is good. Teaching people is good, but crediting the problems of brazil to not having faith in the catholic church is just insane.

    7. Re:Bullshit. by Jedi+Alec · · Score: 1

      Yes, but unfortunately people are much better at doing things that are easy to do, or in this case, not doing something because it is "not allowed", in this case using preventive measures. If there is still anybody present here that thinks you can prevent people from sleeping with each other, whether married or not, please reply to this post. It would be most amusing to read.

      --

      People replying to my sig annoy me. That's why I change it all the time.
    8. Re:Bullshit. by FatSean · · Score: 1

      HAve you thought what wide availability of this drug will mean? If the people are as uneducated as you say, will they be able to understand that the drug will not cure them, and that no real cure is in sight? I would argue that the drug's availability would lessen the fear caused by the AIDS boogyman, probably leading to MORE cases.

      Maybe the Brazilian gov't should try educating their people, rather than fucking them over and then stealing from others to try and fix their mistakes.

      --
      Blar.
    9. Re:Bullshit. by thetman · · Score: 1

      the dominant religion in Brasil is led by some sort of old guy who never had sex and who thinks rubbers are evil...

      So, this is the problem of drug companies? They should have to deal with their own problems don't you think?? You don't have to be highly educated to know unprotected sex and sharing of needles is deadly, a billboard in every down will be sufficient to educate people. Now, this doesn't mean that people will change their behavior even if they know it will eventually kill them.

    10. Re:Bullshit. by tester13 · · Score: 1

      so what is your suggestion? Maybe we should allow a few million people to die of Aids so as to make the message clear. Would that prevent the moral hazzard of just saving lives without holding people accountable?

    11. Re:Bullshit. by Anonymous Coward · · Score: 0

      Oh man... yeah... THATS IT.... the Catholic church should be the role model......

      Now excuse me.......i'm late for my Flat Earth Society meeting, i need to burn a few witches before lunch and my check for some indulgences bounced.........

      Go back to your book of fairy tales..... personally i find the brothers Grimm more beliveable......

    12. Re:Bullshit. by grammar+fascist · · Score: 2

      And if people listened to the other things this "old guy" says...

      Exactly. I'm know I'm going to be modded down to -1 for this, but here's my view:

      I'm glad AIDS exists. I'm glad venereal diseases exist, and are often so hard to get rid of, sometimes deadly, and so very uncomfortable. Why?

      It's a good deterrent for those people who like to practice promiscuity. And, since well over 99% of infections are acquired through pre-marital sex, it's also a good punishment. I'm sick and tired of the entire world saying that blatant disregard of sacred creation itself is a good thing.

      There are some who think it's the wrath of God. There are some who think it's natures answer to unnatural conduct. I tend to agree with both.

      --
      I got my Linux laptop at System76.
    13. Re:Bullshit. by grammar+fascist · · Score: 1

      You are obviously a sad geek who never got laid.. I feel sorry for you.

      No, I'm happily married to a wonderful woman, and I have a beautiful baby girl.

      Next.

      --
      I got my Linux laptop at System76.
    14. Re:Bullshit. by Reality+Master+101 · · Score: 2

      The reason why they infected is not importnt,

      What the hell? You are definitely on acid.

      The reason someone gets a disease is HUGELY important. I feel way more sympathy towards someone who gets a disease that anyone can get versus someone who has AIDS, those of whom pretty much choose to get it (except in extremely rare circumstances).

      Do you feel the same sympathy for a child with cancer that you do a heavy, lifetime chain smoker with cancer? Or a lifetime alcoholic with liver disease?

      I'm not saying that all AIDS patients deserve what they get, and that I have no sympathy at all, but we should never forget that it's a behaviorially spread disease.

      --
      Sometimes it's best to just let stupid people be stupid.
    15. Re:Bullshit. by 1001011010110101 · · Score: 1


      >Do you feel the same sympathy for a child with >cancer that you do a heavy, lifetime chain >smoker with cancer? Or a lifetime alcoholic with >liver disease?

      I feel mostly the same towards both of them. I don't think I'm in position to judge anyone for their choices in life, and can't see the background they came for, what happened to them during their lifetimes. Sames applies to AIDS and any disease.

      Making any kind of difference would be a form of discrimination.

      I think that all of them are humans, and all of them deserve the best treatment they can get. How they happened to get it is not important. At least for me.

    16. Re:Bullshit. by FatSean · · Score: 1

      sure, why not?

      Actually, that's a bit harsh if the people aren't properly educated about the disease.

      How about this, start a mass education campaign. Tell them how to avoid the disease. If the infection rate doesn't start dropping, there is no hope. I wish I could say otherwise, but I don't hold out much hope.

      --
      Blar.
    17. Re:Bullshit. by OAB · · Score: 1

      So you think people should abstain from pre-marital sex because they are afraid, not because they think it's wrong?

    18. Re:Bullshit. by grammar+fascist · · Score: 1

      Although the second reason you mention is superior, I'll take the first for now. Motivations have a funny way of blending together, and sometimes one motivation becomes another one. When I was a child, there were a lot of things I thought twice about because of fear of punishment - now I wouldn't do them because they are wrong.

      --
      I got my Linux laptop at System76.
    19. Re:Bullshit. by Reality+Master+101 · · Score: 2

      I don't think I'm in position to judge anyone for their choices in life, and can't see the background they came for, what happened to them during their lifetimes.

      Unfortunately, you have identified a problem in modern society: this "who am I to judge" nonsense.

      I judge everything and everyone in the world. And I invite everyone in the world to judge me. Sometimes I live up to it, and sometimes not. And I don't always accept everyone's judgements, and not everyone accepts my judgements.

      But it would be far better world if everyone judged everyone else, and everyone held each other up to the highest standards.

      what happened to them during their lifetimes.

      What is in someone's past is completely irrelevent. All that matters is their current actions. Letting people throw out excuses for their behavior is a recipe for letting people screw other people without any consequences. "Hey, I had a rough childhood, so I should be allowed to screw a few people." No, I say!

      Making any kind of difference would be a form of discrimination.

      You seem to be under the impression that all discrimination is bad. It is not. Discrimination for arbitrary reasons is bad. Discrimination for real reasons is not. For example, I don't have friends that are heroin users. Am I being discriminatory? Of course. Am I justified? Absolutely.

      A healthy society must be prepared to have the guts to make moral judgements, one individual at a time.

      --
      Sometimes it's best to just let stupid people be stupid.
    20. Re:Bullshit. by OAB · · Score: 1

      We are talking about adults, not some little five year old.

    21. Re:Bullshit. by Anonymous Coward · · Score: 0

      Kudo's. Well put. You've said something that just needed to be said.

    22. Re:Bullshit. by 1001011010110101 · · Score: 1

      I judge everything and everyone in the world. And I invite everyone in the world to judge me. Sometimes I live up to it, and sometimes not. And I don't always accept everyone's judgements, and not everyone accepts my judgements.

      Ok, that might be valid for you. I don't think that my belief system is the only one, and I accept individuality. And I don't think that my beliefs or rules are the only ones, and that everybody should accept them. I don't meassure everyone against them, that why I said I don't judge others.

      What is in someone's past is completely irrelevent. All that matters is their current actions. You can't examine facts without a context. This usually includes past the past.

      "Hey, I had a rough childhood, so I should be allowed to screw a few people." No, I say!
      I agree with this.

      You seem to be under the impression that all discrimination is bad. It is not. Discrimination for arbitrary reasons is bad. Discrimination for real reasons is not.

      I think discrimination is bad when applied in a whay that judges someone for a belief or attitudes that are not mine. When they think or act different. I completely disagree this.

      For example, I don't have friends that are heroin users

      Bad luck for you, if you need a medical record in order to became friend of someone.

    23. Re:Bullshit. by Darth+RadaR · · Score: 2
      Nice of you to cast judgement to the world, especially since you have all the answers. :) Sure, it's your opinion, but it's awfully childish to condemn those that don't choose to live as you do. In the moral scale of things, I think that celebrating the death of others ranks *much* lower than pre-mariatal sex. So, please, no Mr. Morality bollocks. You've lost the morals game here.


      I'm married, have a daughter, house, etc. and am not speaking as a proponent for $SPECIAL_INTEREST_GROUP, but according to your statement, the lesbians and the impotent are $DEITY's chosen and blessed people. :)

      --
      /*drunk.. fix later*/
    24. Re:Bullshit. by Auckerman · · Score: 1
      "In this age of education, AIDS is generally acquired do to ignoring precautions. Ignorance is no answer."


      I hope a doctor reminds you of that if you are hit by a car that you "didn't see coming" and he refuses treatment.

      --

      Burn Hollywood Burn
    25. Re:Bullshit. by grammar+fascist · · Score: 2

      Sure, it's your opinion, but it's awfully childish to condemn those that don't choose to live as you do.

      What's wrong with condemning a choice? (I'm also tired of worship of "choice." Too many times, calling something a "choice" has gotten people free passes.)

      I'm a believer in exaggeration to make a point:

      I also condemn people who choose to kill other people. Is that wrong? I hope not. Should I be happy if some force (legal or otherwise) stops the practice? I should think so.

      Now - don't think I'm putting sexual perversion in the same boat with murder (some people do), because I'm not. I'm using an application of a principle that you (hopefully) agree with so you can see that the principle is fine.

      Here's the principle: it's fine to be happy with a consequence that deters other people from doing something you believe destroys society. Our "sexual freedom" destroys families. It ruins lives. It transmits disease. It encourages disloyalty, dysfunction, and distrust.

      As for the victims? I feel sorry for those who develop AIDS because they contracted HIV from a blood transfusion, and I wish it wouldn't happen. I even feel sorry for those who develop it through its general means of transmission. However, they chose their consequences when they chose their actions. If someone else can look to them as an example of what not to do, avoid the action and avoid the same consequences, I think that's great.

      --
      I got my Linux laptop at System76.
    26. Re:Bullshit. by Anonymous Coward · · Score: 0

      It's not only case of education, there is a lot of "OH, this will never happen to me".
      As you may know, AIDS longs years without showing it's face, It's difficult to see a aparently super-healthy person and belevied she has AIDS...
      Of course this is wrong, but is not only a case of education, is also "a brazilian tradition"..
      Differences apart, it's like the safe belt case, everyone knows you NEED to use it, but 100% of us use? I've heard the most incredible excuses for not using it....

    27. Re:Bullshit. by Darth+RadaR · · Score: 1

      However, they chose their consequences when they chose their actions.

      You can also say the same thing about people who die in aeroplane crashes. :)

      Our "sexual freedom" destroys families. It ruins lives. It transmits disease. It encourages disloyalty, dysfunction, and distrust.

      That's a pretty tall order. You could...
      s/sexual freedom/sexual disfunction
      s/sexual freedom/drugs and alcohol
      s/sexual freedom/violence
      s/sexual freedom/greed
      s/sexual freedom/government
      s/sexual freedom/war
      ...ad infinitum, though YMMV

      I lay no claim on The Greatest Wisdom of the World, but I put sexual freedom pretty low on the scale of What's Wrong With the World(tm). Sexual freedom has been around for quite some time; it's just more widely published now.

      --
      /*drunk.. fix later*/
    28. Re:Bullshit. by jafac · · Score: 2

      wow. sounds like you're a fascist about more than just grammar. . .

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    29. Re:Bullshit. by jafac · · Score: 2

      please consider the following:

      Your own welfare and safety ARE at stake here.

      The more people "out there" who have HIV infection, the greater the risk to YOU - PERSONALLY of contracting HIV. To say that you don't have unprotected gay anal sex, or take intravenous drugs is NO protection. Goody for you, you're morally upstanding.

      But the fact is - you are still at risk. What if you get into a car accident, and need a transfusion? If there are 5000 infected potential blood donors out there, you're probably pretty safe, though a small chance of infection does exist. With 10,000,000 infected, high viral-loaded dying potential blood or organ donors out there, you're at a bit of a higher risk.

      Plus - that monogamous relationship that you THINK you are in, may not be quite as monogamous as you think.
      Or you could be raped.
      Or you could inadvertantly contaminate your blood with someone else's in any one of MANY other ways - industrial accident, dental procedure, brushing against someone on the street who has an open sore, being involved in a fistfight, or even being an innocent bystander who gets someone pushed into him from a fight, or a mentally unstable homeless person could bite you.

      Admittedly, there are no documented cases of any of these infections, but they're all theoretically possible, none of them are behaviorally-driven, and the risk increases as the percentage of HIV-infected people in the population at large increases, whether you wear a chastity belt or not.

      If you believe that HIV is exclusively behaviorally spread, then I have NO sympathy for you when you contract it in one of the "innocent" fashions. Joe Buttplug down the street catching HIV *IS* your concern. His behavior is *not*. It *IS* a public health issue, because each new person infected is a new incubator for viruses, and a vector for more infections. Treating this person with the drugs reduces the chance of the disease spreading - more effectively than telling Joe Buttplug not to put his pee-pee into any more bottoms. Because inevitably, Joe Buttplug will do with his pee-pee as he wishes.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    30. Re:Bullshit. by ruin · · Score: 2
      I'm glad AIDS exists. I'm glad venereal diseases exist, and are often so hard to get rid of, sometimes deadly, and so very uncomfortable. Why? It's a good deterrent for those people who like to practice promiscuity.

      You can't be serious.

      Sexual promiscuity is bad because (among other factors) it spread certain disease, which ultimately make people unhappy. If these diseases did not exist, then having lots of sex with lots of people would not be a bad thing. (for that reason, anyway). Suppose someone came up with a pill you could take that would make it so that you never had any cavities for the rest of your life. That would be a good thing, right? Oh wait, no. Under your twisted logic, this pill would be bad, because it would encourage people to stop brushing their teeth, and everyone knows that brushing your teeth is very good and important.

      Allow me to reiterate the point. Things are bad for a reason. And I mean a real reason, not some mystically inherent "sacred creation" reason. If that reason goes away, then those things are no longer bad.

      Railing against the possibility of the improvement of people's lives is insane, and the religions that propagate this mentality are responsible for much human misery.

      --
      share and enjoy
    31. Re:Bullshit. by Reality+Master+101 · · Score: 2

      Admittedly, there are no documented cases of any of these infections, but they're all theoretically possible,

      Sorry, I don't live in theory, I live in the real world. I simply will not catch HIV, period. Incidently, transfusion-related infections haven't happened in over 10 years because of the blood screening process.

      Look, I don't wish ill-will on anyone, and I'm glad drugs are being developed to help them. My point is that some diseases are more innocent than others, and AIDS is one of the least innocent. If I was donating my money to a particular cause, I would give $100 to curing pediatric cancer to every $1 of HIV.

      Whether you want to believe it or not, HIV is almost 100% preventable.

      --
      Sometimes it's best to just let stupid people be stupid.
    32. Re:Bullshit. by jafac · · Score: 2

      Sorry, I don't live in theory, I live in the real world. I simply will not catch HIV, period. Incidently, transfusion-related infections haven't happened in over 10 years because of the blood screening process.

      Tell that to the tens of thousands of Chinese that are infected due to blood transfusions. Admittedly, a different process than what we use, but NO screening process is 100% safe.

      To say that it's *almost* 100% preventable is approaching the truth, and the correct attitude.

      The more "other people that you don't care about" get this disease, the further from 100% you are.

      To say that some diseases are more innocent than others is being observant. To insist that the morality of the cure be dependent on the morality of the disease is repugnant, selfish, and arrogant.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    33. Re:Bullshit. by blitzkreig · · Score: 1

      Ignorance may be no answer to the AIDS problems abound in every nation on our fragile planet. There is also no reason for the drug companies to be bullying a nation into purchasing drugs that are developed to make human life better and more bearable. When the drug companies start advertising their drugs, they pay lots of money which, in turn, get passed along to us, the consumer. This is the ROOT cause of the incredibly high prices that we pay in the U.S.. Precisely why the elderly that live near the border of U.S. and Canada drive over the border to buy their medications. The drug companies price gouge the consumer in order to fatten their wallets. The root cause of the worlds problems is selfishness. If Roch had decided to agree to Brazil's price, there would be no problem at the moment. Roch decided to think more about the bottom line and money itself BEFORE they thought about the basic right to life. Poor them. They missed a GREAT philanthropic opportunity here, and they will most likely suffer for it.

    34. Re:Bullshit. by Banjonardo · · Score: 1

      Bullshit. Research before you insult. You might start here: http://www.aids.gov.br/

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

    35. Re:Bullshit. by Anonymous Coward · · Score: 0

      Yes, it's always the people who can't get laid who end up getting married. It's the only way they can be guarenteed sex. No wonder you're so jealous of people who are promiscuous, and you want them to die because of it.

    36. Re:Bullshit. by ryanwright · · Score: 2

      Allow me to reiterate the point. Things are bad for a reason. And I mean a real reason, not some mystically inherent "sacred creation" reason. If that reason goes away, then those things are no longer bad.

      STDs are not the only reason promiscuity is bad. Even if you could magically eliminate them, you still have to deal with broken families. Children being raised without a mother or a father - contrary to popular belief, this significantly affects children in a negative manner. Jealousy, lust, mistrust. You'll never elimate these issues.

      The point that was being made here is that STDs function as a check and balance mechanism. Many people have absolutely no problem tearing their families apart or creating parentless children, but the fear of STDs keeps them in line. Theoretically, the elimination of STDs would result in a huge increase in sexual misbehavior. Broken families. Parentless children. All of the other reasons promiscuity is unacceptable to many, many people. Under that logic, the statement that STDs are good for humanity is almost tolerable.

      --
      -Ryan, with the unoriginal sig
  10. What a fucking disaster by Chris+Hind · · Score: 1

    I hope the Brazilian government gets bitchslapped by as many international bodies as possible for this. Quite apart from the fact that these drugs aren't designed to be used in the conditions found in Brazil (which will mean that strains of HIV resistant to this treatment will be produced there), they didn't pay for it, so they don't get to have it. Shit, it's not difficult for governments to raise funds for this kind of thing - ever heard of taxes?

    Do governments want to pay for medicine to be developed? No.
    Do governments want to reap the benefits of that medicine? Hell, yes.
    Will this lead to more or less investment by the drug companies in medicines suitable for developing world use? Work it out for yourself.

    --
    nal 11
    1. Re:What a fucking disaster by CSC · · Score: 1
      Do governments want to pay for medicine to be developed? No.
      Do governments want to reap the benefits of that medicine? Hell, yes.
      So each and every country should re-invent the same thing over and over to please you?

      Okay. So please build a new language, or pay for the use of English. After all you stole some other country's work.

      --
      -- Colin
    2. Re:What a fucking disaster by haizi_23 · · Score: 2, Insightful
      It's not difficult for governments to raise funds?
      Well, yeah, maybe if they're the US, an EU country or Japan. For everyone else, they're busy trying to figure out how to reschedule their IMF debt so they can perhaps one day have an economy.

      Do governments want to pay for medicine to be developed? Yes. In fact they do. As noted before, check our (the US) budget for AIDS research.

      I think the best analogy for this is something like the Polio epidemics that swept this country in the early 20th century. I don't know that history all that well, but I doubt our government was charging people for vaccinations. And had it been a pharmaceutical company supplying the vaccinations, you can bet that putting their commercial concerns before the lives of children would have had an army of parents throwing bricks through their windows.

      I'm all in favor of free enterprise, and pharmaceutical companies have as much a right to compete in the marketplace as anyone, but there's a time and a place for commerce.

    3. Re:What a fucking disaster by Remote · · Score: 2

      Quite apart from the fact that these drugs aren't designed to be used in the conditions found in Brazil (which will mean that strains of HIV resistant to this treatment will be produced there),...

      What do you mean by "conditions"? Maybe you mean the legal system... Oh, sure, these drugs weren't designed to work in such a framework.

    4. Re:What a fucking disaster by Chris+Hind · · Score: 1

      What the hell? That's the dumbest thing ever. Try the following:

      READ -> COMPREHEND -> POST

      If the Brazilian government wants AIDS drugs, it should either

      1) pay for them from the people who own them or
      2) put the damn money in to research them in the first place

      This is a really simple argument. Sorry that you didn't get it.

      --
      nal 11
    5. Re:What a fucking disaster by Chris+Hind · · Score: 1
      It's not difficult for governments to raise funds?
      Well, yeah, maybe if they're the US, an EU country or Japan. For everyone else, they're busy trying to figure out how to reschedule their IMF debt so they can perhaps one day have an economy.
      Fine. Unfortunately, until such a time as that happens, these countries haven't got the money to buy AIDS drugs, so they don't get them, just like they don't get to, for example, annexe oil wells belonging to other countries in order to improve their financial position. Now if we wanted to donate these drugs to these countries, by putting a couple of percent on income taxes to pay for it, that would be fine. Fancy that? Then campaign and vote for it. Just because someone is poor does not give them the right to be a theif.
      Do governments want to pay for medicine to be developed? Yes. In fact they do. As noted before, check our (the US) budget for AIDS research.
      Then the US should reap some of the benefit of that research. Brazil shouldn't. Do you see why? It's because the US PAID and Brazil DIDN'T. If the US votes to give some of it away: it's theirs, that's fine. If someone decides to steal it: fuck them.
      I doubt our government was charging people for vaccinations.
      I doubt that they WEREN'T. Or was there a sudden epidemic of "no one paying tax" around the time of polio?
      there's a time and a place for commerce.
      Yep. And the time and place is now. Hopefully there'll be some way to sue Brazil until its pips squeak over this.
      --
      nal 11
    6. Re:What a fucking disaster by superdan2k · · Score: 1

      Buddy, a protease inhibitor is not a strain-specific drug. What you're thinking of is a vaccination. A protease inhibitor attacks a step in the virus replication process. It doesn't attack the strain itself.



      While yes, it is possible for a government to raise money via taxes, you also have to remember that the world is a free market economy. The companies can charge whatever they like, but they had better prepare themselves for stuff like this if they continue to price gouge.



      Do governments want to pay for medicine to be developed? Ideally, no. They don't. In an ideal situation, the drug companies would do it by themselves, and market the drugs at a reasonable cost so that the people who needed them could have access to them. Governments, however, DO fund research and development. This, should have an impact on the cost to the end-user, but it doesn't.



      Do governments want to reap the benefits of the medicines developed by drug companies? Yes. But you know what? So does everyone from the end-user to the company that developed it.



      Your last question is bunk. Drugs aren't developed for a particular economic area anymore. They're developed for target audience, marketed as an absolute necessity, and the price is driven up because in first-world nations, people have health insurance companies that will cover it. If they go to sell these drugs in a third world country and cut the rates, the insurance companies in the first-world nations are going to wonder why they don't get these prices, and much legal mayhem will ensue.

      --
      blog |
    7. Re:What a fucking disaster by Anonymous Coward · · Score: 0

      does slashdot have a killfile/killfilter/ignore feature?

    8. Re:What a fucking disaster by aprentic · · Score: 1

      Wow. You're not only rude, you're an idiot too.
      Governments certainly do pay for medical development. Ever heard of the NIH? They are the single largest source of medical research funding, and they are paid for by the government.

    9. Re:What a fucking disaster by Anonymous Coward · · Score: 0


      >Do governments want to reap the benefits of that >medicine? Hell, yes.

      It's a good thing for you that you are born in a rich country. Can you agree it's just luck and can you imagine you won't think the same way if you were born in the third world?

      CLO
      Take care of your karma :)

  11. Setting an excellent example by James+Foster · · Score: 1

    How commendable.
    Its quite disgusting that anyone actually patented such a thing in the first place. Human life is sacred and every life is worth more than all of the money in the world.
    Then again, given the sick and twisted world of today, it would be quite naive to think that someone WOULDN'T patent such a thing.
    Given all the money that is donated into research for medecines into diseases like AIDS, surely any organization that manages to create that medecine has been funded by the donations. Surely noone needs to profit off such a thing.

    It's nice to see this patent being disregarded.

    1. Re:Setting an excellent example by Anonymous Coward · · Score: 0

      This isn't an example, they are not going to give this medicine away. They are going to charge for it, probobly the same if slightly less than Roche. They don't care about the people only the money. And since when has human life been worth anything, in most of the world life means very little, and when ever we go to war we make it even less so.

    2. Re:Setting an excellent example by Anonymous Coward · · Score: 0

      Life might be treated like it means nothing, but don't you think it's worth more than its given credit for?

    3. Re:Setting an excellent example by Anonymous Coward · · Score: 0
      If that is your belief great. When you start donating thousands of your own dollars to finding new drugs then you can talk. What's that, you haven't given away every extra penny you earn to make new drugs? Why not, you just said that human life is worth more than all the money in the world? Oh, you meant OTHER peoples money.

      This decision is going to hurt millions of people in the long run. These drugs extend the lives of those with HIV/AIDS - this is not a cure. How many drug companies do you think will now spend billions of dollars to look for a cure that they can then give away for free? Try 0.

      I don't like the marketing of drugs and I think general funding for medical research is a good thing, especially by rich countries like the US. But this is a mistake that will hurt people in the long run.

    4. Re:Setting an excellent example by Stephan+Schulz · · Score: 1
      This isn't an example, they are not going to give this medicine away. They are going to charge for it, probobly the same if slightly less than Roche.

      If you had read the original article, you would know that yes, they are giving the drug away. In fact, they are doing it even now (at the cost of 28% of their total medical budget). In most civilized and semi-civilized countries on this planet, the right to adequate medical care is considered one of the most basic human rights.

      International law explicitely allows for compulsory licensing of patents in the case of a national emergency. Given the AIDS rates in many third-world countries, emergency is a rather weak word to describe the situation...

      --

      Stephan

    5. Re:Setting an excellent example by codeforprofit2 · · Score: 1

      Mod this one up.

      Right on point.

  12. Lets keep dreaming for a while by Jedi+Alec · · Score: 1

    Maybe some day, a post like yours would be moderated down for being too damn obvious. Wouldn't that be beautiful? (nothing personal)

    --

    People replying to my sig annoy me. That's why I change it all the time.
    1. Re:Lets keep dreaming for a while by Erasmus+Darwin · · Score: 2
      "Maybe some day, a post like yours would be moderated down for being too damn obvious."

      Personally, I'm hoping that some day it'll get modded down for missing the obvious fact that if people circumvent the intellectual property rights of drug companies, the result is less money for research, less new drugs, and ultimately less lives saved.

    2. Re:Lets keep dreaming for a while by Anonymous Coward · · Score: 0

      it wasn't as though brazil unilaterally decided, "hey, let's break international patents." the drug company had the opportunity to negotiate a reasonable payment scheme with the country and refused to do so. maybe it'll be a wakeup call to companies that they need to look beyond the bottom line of an accounting register.

    3. Re:Lets keep dreaming for a while by Anonymous Coward · · Score: 0

      Actually, the obvious fact that you are missing is that drug companies spend more money marketing their drugs than they do developing them. How much money do you think Pfizer had to shell out for their Viagra racing team?

    4. Re:Lets keep dreaming for a while by TresTresMondoMod · · Score: 1

      Who cares, NASCAR is AWESOME!!!

    5. Re:Lets keep dreaming for a while by SubtleNuance · · Score: 2

      Personally, I'm hoping that some day it'll get modded down for missing the obvious fact that if people circumvent the intellectual property rights of drug companies, the result is less money for research, less new drugs, and ultimately less lives saved.

      WRONG!

      BigPharm spends more money on Marketing than they do Research AND that research enjoys heavy government subsidy (grants) AND tax breaks.

      Americans are so blinded by FreeMarket Capitalist Dogma to see that they are dying for profit. Literally.

      Please read:
      http://www.mercola.com/2000/june/24/pharmaceutical _industry.htm

    6. Re:Lets keep dreaming for a while by Erasmus+Darwin · · Score: 1, Flamebait
      "Actually, the obvious fact that you are missing is that drug companies spend more money marketing their drugs than they do developing them."

      And...?

      Marketing -> more sales -> more revenue -> more research.

    7. Re:Lets keep dreaming for a while by Erasmus+Darwin · · Score: 2
      "http://www.mercola.com/2000/june/24/pharmaceutica l_industry.htm"

      I can't help but notice that the article tends to focus on the pharmaceutical companies developing and promoting "me too" drugs that don't really do much that's new, but rely on advertising and promotion to carry them along. As I understand it, the "me too" drugs are more profitable but less helpful overall.

      However, in the case of this drug, it seems to be one that's important enough and unique enough that Brazil has chosen to embark on the rather serious task of disregarding the world patent and beginning local generic manufacture. Further, one could argue that the Brazil situation will only further serve to scare pharmaceutal companies away from innovative, life-saving drugs, causing them to go with research in drugs that are less likely to be "pirated" for the short-term public good.

    8. Re:Lets keep dreaming for a while by n0-0p · · Score: 1

      There is validity to what you wrote, but you shouldn't ignore the fact that drug companies primary goal is to make money; sometimes that conflicts with the more altruistic goal of curing disease.

      Case in point:
      In the early 1980's long term studies were completed that linked the cause of many ulcers to bacterial infections. At this time several drug companies were making a hefty profit on expensive anti-ulcer medication. Now these are the kind of drugs that a patient had to take pretty much for the rest of his or her life, so that's a continuing source of revenue. The results of the study were published but went pretty much nowhere for about a decade. Doctors recieve a lot of their information on treatments and procedures from drug company reps. The drug companies ignored or buried the information because that would mean trading a high paying life time customer for a two week dose of cheap antibiotics. Eventually the information on bacterial causes of cancer did make it to the public, but should it really have taken ten years?

      Just a thought.

    9. Re:Lets keep dreaming for a while by reemul · · Score: 1

      That's just blackmail. "Come to a lower price, or we'll just ignore our international treaty obligations on intellectual property and *really* rip you off." Where is the upside in that? The pharma company either buckles, validates the actions of Brazil, and sets up a precendent for every other country with an "end justifies the means" attack on medical patents -or- they merely get screwed.

      If you don't respect patents, then folks will either stop doing the research, or they will just keep the processes secret. That's right, they go from documented but protected to completely closed. Patents do two important things - they protect the property, but they also describe how the item works. If the pharma companies are already getting ripped off despite the supposed legal protections, they'll just stop filing the patents. Anyone who wants to make their own version will have to do their own research and come up with their own manufacturing process, and do separate studies on the impact of _their_ version of the drug. It's not just a simple case of duplicating the chemical structure, like making a copy of a binary file. It requires a manufacturing process that can get useful yields of precisely the right chemical, with all of the bonds having the right orientation. Having a double bond go the wrong way can make a cure into a poison, and everyone making the pill just from an analysis of an original pill they bought somewhere will have to figure it out on their own. Universities and research labs will have to reinvent the wheel to do the in depth studies they want and need to do. Yep, that'll be a *big* help in the fights against disease.

      --
      You're just jealous 'cuz the voices talk to *me*
    10. Re:Lets keep dreaming for a while by SubtleNuance · · Score: 2

      the "me too" drugs are more profitable but less helpful overall.

      Me-too Drugs are created when companies must side-step patents. If we have no patents than this becomes unnecessary... am I missing something in your point.. you seem to be agreeing with me.

      go with research in drugs that are less likely to be "pirated"

      Did you read the article? You realize that the industry serves itself, public health is not a concern.

      the short-term public good

      ...you are 100% mis-understanding this situation, the 'SHORT-TERM' public good occurs when some BigPharm can lock up a drug for themselves, and use their publicly-subsidized research to extort profit. The LONG TERM good would be served to eliminate private drug-patents and the private health industry and make people healthy: all people, in all possible ways, all the time. The public only has to pay enough to make themselves and their neighbours healthy - not put some fat-boss in a new Porsche in Beverly Hills.

    11. Re:Lets keep dreaming for a while by supersnail · · Score: 1

      I would be careful about making any predictions where money and healthcare are involved.

      The economics of health care are extremly complex. All the normal supply and demand type equations still apply, but, the "demand" is infinate.

      Question:- how much would you be prepared to save a loved one?

      Answer:- Everything youve got, plus everything you can borrow, plus anything you can steal.

      The sheer wierdness of the health care system in the UK is a case in point. Its actaully very efficient in terms of money (the UK spends less per person on health care than any other first world country), but we have the lowest paid doctors, the longest waiting lists, and the grottiest hospitals.

      --
      Old COBOL programmers never die. They just code in C.
    12. Re:Lets keep dreaming for a while by Anonymous Coward · · Score: 0

      but should it really have taken ten years?

      Apparently so, because otherwise someone would have commercialized it ten years earlier and made their billions.

      Please take your 'pill that turns water into gasoline that the oil companies are keeping secret' anecdotes to the Urban Folklore usenet newsgroup, please.

      Thanks.

    13. Re:Lets keep dreaming for a while by SubtleNuance · · Score: 2

      Please see:
      http://www.washingtonmonthly.com/features/2000/0 00 7.marmorsul.html

      It speaks to health care costs && approaches. I am Canadian, and we too have a national health system, and I am extremely gratefull for it. The alternative is unthinkable.

      From the Article:

      place American and Canadian performance in a comparative context. She failed to tell her audience (or did not know) that Canada insured 100 percent of its citizens for $2,250 per person in l998 while the United States expended $4,270 per person insuring only 84 percent of our citizens.

      Basically - dont let Blair or his Neo-Liberal twits sell you out to the Yankee Health Businesses - Canadians are watching the WTO, FTAA and the rest licking their lips at the thought of putting us all under their clutches... I wont let them, and YOU SHOULDNT LET THEM!

    14. Re:Lets keep dreaming for a while by astar · · Score: 1

      Let us recognize reasonable limits to marketing. For instance, there is an international convention that class II (highly addictive drugs) not be marketed except to doctors. Yet in the United States such drugs, for children, are now being marketed to parents. These drugs are not Ritilian, but have the same purpose, whatever that is. I believe Rouche is among those doing such marketing.

      Please recognize that the above behavior will add to R&D available revenue, as in your equation, but the real motivation is shareholder's value in both cases.

      In an extended discussion, we could develop a number of examples where shareholder's value is not properly the highest goal. In general, these come under the rubic of the Common Good, otherwise known in the US as the General Welfare. These concepts can be *economically* treated as preserving and enhancing the future production of wealth of the society. As a parenthetical note, let us observe that wealth is not money, meaning that in a period such as ours, money is a poor measure of the economic well-being of the society.

      Does the common good have a non-economic component. Indeed it does. While people try to address the Brazilian case in moralistic terms, I mistrust that somewhat. The essential moral component is the will to serve the common good, also called agape, with an accent. Brazil's governemnt is to be praised for their will to serve their people's common good.

      Did they implement their will in the best way? I think they did okay, but if not, as a nation-state, they get to chose. The sin is the failure to chose.

      As a closing note, since the establishment of the United States, the primary domestic determination of the legitimency of a govenment has been its committment to the general welfare. Which government is more legitiment: US or Brazil?

    15. Re:Lets keep dreaming for a while by Phil-14 · · Score: 1

      I was wondering, if patents are evil, does
      this mean that things will get better when we
      go back to the stage of development when everything
      was a trade secret?

      --
      (currently testing something about signatures here)
    16. Re:Lets keep dreaming for a while by Pxtl · · Score: 2

      Heres the difference - anyone who knows anything about chemistry knows that's ridiculous. The oforementioned story is quite possible. Unlikely maybe, but possible. And anyone who knows anything about economics knows a long list of folks who'd be willing to be that way.

    17. Re:Lets keep dreaming for a while by SnapShot · · Score: 1

      First I'll admit that I'm pretty conflicted about this story and I'm not sure what to believe (that's why I'm reading other people's posts, I guess). But you have one comment, I'd like to respond to...

      Anyone who wants to make their own version will have to do their own research and come up with their own manufacturing process, and do separate studies on the impact of _their_ version of the drug [replace "drug" with software/business method/anything else that has rocked /. in the last year or more].

      Isn't this exactly the kind of world many of us in software development would like to see? Our code is copyrighted (and licensed through GPL, maybe) but the idea's are open to the public. Sure, I might need to write my own .gif reader/writer, but the idea would be free.

      If patents were applied to the drug world the same way they are applied to software, we'd have companies like Roche with patents on "the ability to cure or slow the spread of HIV" as apposed to patents on specific medicines. That REALLY would kill research into AIDS...

      --
      Waltz, nymph, for quick jigs vex Bud.
    18. Re:Lets keep dreaming for a while by Anonymous Coward · · Score: 0

      suck it communist eurotrash

    19. Re:Lets keep dreaming for a while by WNight · · Score: 2

      It's such an intellectual passtime, a real thinking-man's game.

      Left. Left. Left. Hey, another Left. etc.

      What intellectual giants.

      If you're gonna be into racing, don't watch NASCAR. Watch rally racing, where they have drivers with skill.

    20. Re:Lets keep dreaming for a while by Anonymous Coward · · Score: 0

      It speaks to health care costs && approaches. I am Canadian, and we too have a national health system, and I am extremely gratefull for it. The alternative is unthinkable.

      And how many new AIDS treatments (or treatments for anything else) have been developed in Canada? Hmmmmmm?

    21. Re:Lets keep dreaming for a while by TresTresMondoMod · · Score: 1

      Rally is cool but they need to get some serious V8 engines before they'll ever be taken seriously by Americans. No one can argue the skill involved, but racing against a clock makes for olympic scale boredom.

  13. It concerns me a little bit... by Lobsang · · Score: 1

    The attitude is correct IMHO. To hell with IP laws when human lifes are in danger. However, knowing Brazil from inside (as a Brazilian), I'd say money will only be shifted from the hands of the lawful IP holder to the hands of a few "selected" companies/people inside the country. Do not be fooled into thinking the people will have cheap access to these medications.

    I truly hope I'm wrong.

    1. Re:It concerns me a little bit... by Remote · · Score: 2


      However, knowing Brazil from inside (as a Brazilian), I'd say money will only be shifted from the hands of the lawful IP holder to the hands of a few "selected" companies/people inside the country.


      You can't be serious about that. Procurement process is absolutely public. Yes, laboratories will make money out of this, but the money will go to the lowest bidder that qualifies technically. You don't want any home brewery making this medicine, right? And even if the law didn't dictate things to be that way, interest groups fighting for the good of HIV-positive people in Brazil are *very* powerful, and the press loves them, and we're having elections next year. No, you can't be serious.

    2. Re:It concerns me a little bit... by Anonymous Coward · · Score: 0

      I think you have too much faith in government, especially Brazil's.

  14. Already discussed at WTO by famazza · · Score: 1

    WTO have already agreed with this politics not only in Brasil, but also in Africa. The problem is that Africans countries have no financial resources to build factories, but if they raise the money they also can break the patent.

    WTO agreed with this because here in Brasil drugs AIDS are distributed for free (as beer) by the government, with no costs for carent families.

    Brasil (yes, I prefer with the 's') will also export cheaper AIDS drugs to Africa and other poor countries.

    Hope this help to end all the pain...

    --

    -=-=-=-=
    I know life isn't fair, but why can't it ever be un-fair in MY favor!?
    1. Re:Already discussed at WTO by l33t+j03 · · Score: 0
      WTO agreed with this because here in Brasil drugs AIDS are distributed for free (as beer) by the government, with no costs for carent families.


      You don't have a lick of economic sense do you son? To you, there are no costs associated with drugs distributed by the government. You're the reason why Napster's for-pay service would never work, why micropayments aren't feasible, why DVDs have to be encrypted. You are too foolish to realize that somewhere some cash has to change hands in order for damn near everything to exist.


      Fucking dumbass.

    2. Re:Already discussed at WTO by Anonymous Coward · · Score: 0

      Hey! South Africa had a series of well publicised law court confrontations with a bunch of medical companies recently over *exactly* this issue, with the med firms deciding to settle out of court, and SA being allowed to produce and deploy its own copy of the patented drug. And yes, they do have the finances and know-how to implement this (unless rascist attacks on whites has driven all those with technical know-how out already).

      A problem that they are not going to solve, and which I bet also exists in South America is that effective treatment with these drugs requires *absolute* and *rigorous* control. You miss a couple of treatments, and you might as well not have begun treatment.

      The ability to exercise this control over rural patients (and even urban ones) does not exist in Africa. Treatment with these drugs will fail, and may be harmful, as the virus may well develop immunity when exposed to lower / incorrect dosages.

    3. Re:Already discussed at WTO by fgn · · Score: 0, Offtopic

      > Brasil (yes, I prefer with the 's')

      And you would be wrong... Brazil in English is spelled with a 'Z' and in Portuguese with a 'S'.
      As your post was in English...

      Do you spell Italy as Italia? Germany as Deutschland?

    4. Re:Already discussed at WTO by Anonymous Coward · · Score: 0

      Isn't it shameful how the savage niggers are chasing out the White folks? If there was ever an example of biting the hand that feeds you, this is it.

  15. Good News! by L-Wave · · Score: 1

    Finally! hearing news like this is great! sometimes it makes you wonder when people have patenets and jsut worry about moeny and PR, brazil is doing the right thing.

    "Damn the man." -Empire Records

    --
    I SURVIVED THE GREAT SLASHDOT BLACKOUT OF 2002!
  16. Finally. . . by Wire+Tap · · Score: 1

    It is refershing to see that some people still care about people, and not just their security...greed. Props to the Brazilians who are spearheading this affair.

    --

    Man is born free; and everywhere he is in chains.

  17. from the life-before-dollars dept by jeffy124 · · Score: 2, Informative

    I think it's good to see that there are some governments out there not looking out for corporate interests when it comes to a person's well being. While the Swiss company will probably sue out the wazoo against the government of Brazil for patent infringement, I beleive Brazil in this case has set an excellent precedent regarding patents on medicine that hold the potential to keep someone who is terminally ill from dying.

    Brazil has also set many other precedents, including one that US (and the rest of the world) has to yet catch on with - clean emission alcohol powered cars. Unfortunately, because of who we have at 1600 Pennsylvania, I don't expect many of these to be around until after he leaves office.

    --
    The One Rule Of Chess You'll Ever Need: Don't play someone who carries a kit in their bookbag.
    1. Re:from the life-before-dollars dept by jeffy124 · · Score: 2

      I simply did a search on google for a quick link to explain what an alcohol/ethanol powered car was and it's benefits. The Clinton Administration focused on electric cars. They wanted car makers to develop those types of vehicles for the mass market. Unfortunately, car makers and researchers are finding that electric cars are not as feasible as they once thought they were, hence the reason alcohol as an alternative to gasoline. Brazil is one of only a few (if not only) countries out there to embrace such a vehicle, as they have somewhere in the neighborhood of 4 million alcohol cars.

      The reason I say that GWB won't do much about alcohol (and other alternative fuels) powered cars is because of his own corporate interests. He is a former oil company executive and during his tenure as Governer of Texas, he showed his support for oil companies multiple times, and he has already shown such support as President. Hence he (and his administration) will not be embracing alternative fuels, as they will be hurting the oil industry in doing so.

      --
      The One Rule Of Chess You'll Ever Need: Don't play someone who carries a kit in their bookbag.
    2. Re:from the life-before-dollars dept by Phil-14 · · Score: 1

      About the ethanol thing... the Feds (yes,
      run by George Bush) are currently pushing
      ethanol as a fuel additive to produce cleaner
      burning gas; they're currently being fought
      by the state of California (yes, and their
      ecologically "correct" Governor Grayout Davis)
      who says that cleaner gas isn't needed in most
      of the state. I know this doesn't conform to the
      illogical prejudices of most of the people here,
      but I suggest checking the LA Times for more info.

      --
      (currently testing something about signatures here)
    3. Re:from the life-before-dollars dept by ryanwright · · Score: 2

      hence the reason alcohol as an alternative to gasoline

      Hmmmmm.... what's this going to do to open container laws? ;)

      "But officer... that 12 pack of Bud in the back seat is my reserve tank!"

      I can see it now: Drunks on the side of the road, pissing into their gas tanks trying to make it home... Teenagers running a fuel line from the tank right into a dash-mounted tap... New laws requiring horrible tasting additives to prevent people from drinking their gas...

      --
      -Ryan, with the unoriginal sig
    4. Re:from the life-before-dollars dept by jeffy124 · · Score: 1

      i'm sure you recall the scene from the Simpsons where Homer spotted a sign saying "Alcohol Powered Cars" at a car show. Thought bubble appears, showing him a gas station with a gas tank labeled "Gasahol." Taking the nozzle back and forth from the car, he's saying "One for you, one for me, one for you, one for me ..........."

      --
      The One Rule Of Chess You'll Ever Need: Don't play someone who carries a kit in their bookbag.
  18. Oh great. by The+G · · Score: 1

    So, in another few years, world governments will be able to make whatever they want regardless of patents, while private citizen coders won't be able to write a line of code for fear of tripping over the patents that governments have even less reason than ever to regulate.

    Governments and corps in a spat. Oh boy. Whichever way you cut it, the civilians lose.
    --G

    1. Re:Oh great. by Jedi+Alec · · Score: 1

      Somehow the fact that you're comparing Aids-drugs and lines of code concerns me. I prescribe a two week cure of real-life experiences. Go walk in town or something...

      --

      People replying to my sig annoy me. That's why I change it all the time.
  19. This is not a good trend to cheer. by Shivetya · · Score: 3, Interesting

    There are a few reasons this is a bad trend. Now they are using a public health problem as an excuse to void a valid international patent because they did not get the agreement they wanted. This plays very well in the press, "bad evil company would rather see people die than sell their stuff cheaper" instead of saying "country refuses to pay a fair price for drugs to save its own people"

    Want a story that is similar, but on a more "person" level. White farmers losing their property in Zimbabwe, because its not fair that they have it.

    This is the new trend, government are going to take what they want and justify it in any shape or form. While they start off doing this with the cover of "saving lives" how long before it becomes anything they want?

    So here are some of the real problems.

    1. Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference. (see South Africa's example - do it or we take your companies assests)

    2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement).

    3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"

    4. Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces.

    When do we stop? Who can judge what is a fair price for something? Who can judge what can fairly be patented?

    Apparently people are willing to allow those with the guns to do it, and not realize its the first step to losing their own rights.

    --
    * Winners compare their achievements to their goals, losers compare theirs to that of others.
    1. Re:This is not a good trend to cheer. by Rupert · · Score: 2

      If the drug companies were charging a fair price, this action wouldn't have been necessary.

      The Brazilians are making the drugs themseleves. They are covering all the equipment, raw materials and labor. What they aren't doing is paying the exorbitant patent licencing fees, that are decided, rather like college tuition, based on how much you can afford and then some.

      Yes, the drug companies need to recover their costs (and make a profit). An AIDS treatment will sell like hot cakes right up until a cure is discovered. Moderate, non-prejudicial licence fees will give them that. What it won't do is please the stockholders of the drug companies who bought in at a price that makes the dotcom bubble look sane, and now expect returns.

      --

      --
      E_NOSIG
    2. Re:This is not a good trend to cheer. by hanwen · · Score: 1
      with the cover of "saving lives"

      How can saving life be a "cover"? And what if it were?

      Get back to reality; people are dying here, and this is what can save them. How can there be any argument for not helping them?

      --

      Han-Wen Nienhuys -- LilyPond

    3. Re:This is not a good trend to cheer. by HEbGb · · Score: 1, Flamebait

      The clear argument is, that it is wrong to steal, even if it saves someone's life. Period.

      The Brazilians are crooks for doing this, plain and simple.

    4. Re:This is not a good trend to cheer. by CSC · · Score: 1
      Want a story that is similar, but on a more "person" level. White farmers losing their property in Zimbabwe, because its not fair that they have it.

      This is the new trend, government are going to take what they want and justify it in any shape or form. While they start off doing this with the cover of "saving lives" how long before it becomes anything they want?

      Uh, why do I think of Native Americans when I read this?

      Once more the attitude is "do as we say, don't do as we do".

      2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement).
      It's already that way: the only region specific drugs are for rich regions. So, anyway, the third-world doesn't get anything from this research.
      When do we stop? Who can judge what is a fair price for something? Who can judge what can fairly be patented?
      Looks like you just decided that you hold The Truth.
      --
      -- Colin
    5. Re:This is not a good trend to cheer. by hanwen · · Score: 1
      that it is wrong to steal, even if it saves someone's life.

      So, explain that to the 3-year kid that got AIDS from his mom.

      Being right or wrong doesn't get you anywhere, especially if you've got AIDS. I for one would applaud my government if they gave me the medicine I can't afford.

      Would you not?

      --

      Han-Wen Nienhuys -- LilyPond

    6. Re:This is not a good trend to cheer. by Ami+Ganguli · · Score: 2
      The clear argument is, that it is wrong to steal, even if it saves someone's life. Period.

      Clear to you perhaps, but I have to disagree. Stealing is wrong, but so is letting somebody die. Of the two, stealing is definately the lesser evil.

      If I'm ever in situation where I can save my life or somebody else's simply by stealing something, I hope I do it. I would have to overcome a lot of social conditioning and I might not have the courage. I suppose that's what distinguishes heros and great leaders from regular folk like me - they have the courage to make difficult decisions.

      --
      It is tempting, if the only tool you have is a hammer, to treat everything as if it were a nail. - Abraham Maslow
    7. Re:This is not a good trend to cheer. by BroadbandBradley · · Score: 2

      3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"

      and you think this is bad? Are you Satanic and trying to bring on the end of the world or something?
      Public good means that ALL OF US GET RICH, and there's more to riches than money.

    8. Re:This is not a good trend to cheer. by merlin_jim · · Score: 1
      First off, let me say that I sympathise with all the AIDS sufferers out there, and say that I can definitely empathise with their friends and family members, having been one myself.

      Yet, despite my rather biased perspective on this issue, I do not believe that blatantly breaking the law is the answer in this case. I do believe that international patent law should be different, but believing that a law should be different is never a good reason to break it.

      I understand that drug companies are out to make money, and that if they have knowledge or a device that cost them money to get, then they have a right to try to sell it at a profit, and keep it proprietary to boot. Open Source only works when its willing on all sides.

      But, frankly, a lot of what they practice is not profit. It's extortion. We need some way to regulate their prices to a fair price. Let's see, quick ideas:

      In a capitalist economy, this is done through competition. Can't compete with proprietary technology... no way to get a competitor fairly.

      Okay, supply/demand laws... These basically boil down to: "The price of something is optimally set by the consumer at the price the consumer is willing to pay. This price goes up as demand increases, and goes down as supply increases." Hmmm... no control over supply. Demand, unfortunately, will be set nearly world-wide by the U.S. Health Insurance industry. Who, of course, will want to pay as little as possible, but will want to make it necessary to have health insurance to get treated. That's their motive, and I feel it won't do any good to any sufferers who don't have health insurance.

      U.S. (or other big country) legislature could help here... either by limiting the cost of treatment (which I do NOT support), or by creating a welfare system that sets a cap at the maximum cost of treatment. This second option I do support, and am even willing to spend my tax-dollars to do. It is, as far as I can see, the only legal and (more importantly) morally right way to reduce the cost of these treatments while preserving the patent-holder's right to profit.

      Did I miss anything, anyone? Any other ideas on how this should work? What about the ability to share patented information to synthesize a cure? Anyone with any ideas on how to address that?

      --
      I am disrespectful to dirt! Can you see that I am serious?!
    9. Re:This is not a good trend to cheer. by alen · · Score: 2, Insightful

      While I support patents, Has Brazil signed any treaties or agreements supporting others' patent laws? If not then they can legally make all the drugs they want.

    10. Re:This is not a good trend to cheer. by Svenne · · Score: 1

      Yes, monetary profit is always more important than life.

      --

      Slagborr
    11. Re:This is not a good trend to cheer. by BlueStreak · · Score: 2, Informative

      This appears to be a trend with Brazil.

      For a while, Canada has been fighting Brazil over subsidies in their aviation industry. From what I understand, the government gives big subsidies and extremely low or no interest loans to buyers of Brazilian aircraft.

      Canada brought them to the WTO and won (it was hurting Bombardier, which BTW the government controls part of because it saved it's ass many years ago). Regardless, the Brazilans have refused to comply or fully comply and there's been a little on again, off again trade war (a while ago it's with beef).

      All this seems so childish but, when it comes to doing AIDs drugs, the people they are really hurting are those in the western countries who will probably end up paying more to offset any type of loss.

      On a related note, India is doing the same thing with AIDs drugs: ignoring International IP to make cheap versions. The difference was the Indian government & pharmaceuticals planned on selling them mostly in Africa (sorry, I don't have a link to the story).

    12. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0

      There are a few reasons this is a bad trend. Now they are using a public health problem as an excuse to void a valid international patent because they did not get the agreement they wanted. This plays very well in the press, "bad evil company would rather see people die than sell their stuff cheaper" instead of saying "country refuses to pay a fair price for drugs to save its own people"

      The question is, was it a fair price? The answer is no it was not a fair price. 28% of a health budget on one drug is way too much.

      Want a story that is similar, but on a more "person" level. White farmers losing their property in Zimbabwe, because its not fair that they have it.

      This is totaly different. Lives are not at stake here, property is. If on the other hand, White famers are being starved to death in Zimbabwe, it would be a totaly different situation entirely. Property is a luxery, medicine should not be.

      This is the new trend, government are going to take what they want and justify it in any shape or form. While they start off doing this with the cover of "saving lives" how long before it becomes anything they want?

      You mean like corperations do allready? Most of the research for these drugs are done in public institutions. The diffrence between corperations and governments is:

      A.) Governments are accountable to the people of the country. Corperations are only accountable to their majority shareholders.

      B.) Governments are accountable to the international community (UN). Corperations have no international reglitory orginization.

      Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference

      ...or have the company re-think it's pricing policies.

      Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement).

      Generaly those drugs are developed by public institutions anyway. There is not a lot of money to be made in South Africa/America.

      Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"

      I haven't seen any proof that this will happen looking at South Africa who did a similar thing a little less then a year ago.

      Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces.

      Yeah right, a company is not going to sell something to someone.

    13. Re:This is not a good trend to cheer. by HEbGb · · Score: 2

      Emotional pulls make for poor arguments ("Won't someone please think of the children?!")

      Resorting to thievery and lawlessness, whatever the cause, is morally repugnant. Especailly if done by a government.

    14. Re:This is not a good trend to cheer. by juhaz · · Score: 1

      Sure it is, but just watching and letting their people die - especially if done by a government - which is, or at least should be, _there for the best of those same people_ - when they could prevent it, is FAR more repugnant.

      Watching people die when you could do something is not murder, but its damn near, and that is certainly greater evil than mere stealing.

    15. Re:This is not a good trend to cheer. by Quila · · Score: 1

      3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"


      At least in the U.S., the only reason IP is allowed in the first place is for the public good. If you're jacking your prices on a necessary drug, preventing thousands from receiving treatment, that's not in the public good, and you deserve to have your rights curtailed. Also, IIRC, their R&D costs aren't that high, since the government funds much of the research in the first place.


    16. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0

      Jeez man you are out of it.
      Most first world industries are _heavily_ subsidized. Tech, agriculture, and aerospace in particular....
      The pentagon is a huge mechanism for dispersing public money into private industry. Boeing, for example, gets billions to develop military craft, then reuses the research for commercial planes. No wonder they are the biggest in the world.

    17. Re:This is not a good trend to cheer. by Hadean · · Score: 3

      >While they start off doing this with the cover of
      >"saving lives" how long before it becomes anything
      >they want?

      This is some of the most annoying rhetorics I've ever heard on Slashdot... If we let kids watch horror movies, how long until they start watching porn and God(tm) knows what else? If we let marijuana go legal (for health reasons, of course), how long before we legalize cocaine? If we let guns in the hands of kids (for hunting, of course), how long before my 5 year old baby starts to shoot one? You can use that sentence for ANY bloody argument, and it's starting to tick me off - how many times do Slashdotters have to hear/say that? How about, if we start letting pharmaceutical companies charge whatever they want, in spite of the deaths of thousands, when will they stop and actually care about humans? You'd think after the UN caught a half dozen of these Companies for fraud (as I mentioned in another reply, sending expired medicines, etc.) that people would start to look at them more critically... I guess not... Research, no matter by who, is automatically a Good Thing (tm) to some people I guess... even if it means to the deaths of others.

    18. Re:This is not a good trend to cheer. by codeforprofit2 · · Score: 1

      When it comes to drugs the costs are typically not in it's production but in the research&development that made it possible.

      Manufacturing is often just some spare-money when you compare the costs.

    19. Re:This is not a good trend to cheer. by Hadean · · Score: 2

      I guess the old question of.. If your family was starving, and you had absolutely no money, would it be wrong to steal a loaf of bread to keep them alive? Or, to be more appropriate in this case, would it be wrong to steal a loaf of regenerating-bread that can used to keep someone alive until a natural death?

      But we know YOUR answer: you'd prefer to see people die on the streets of starvation...

    20. Re:This is not a good trend to cheer. by dinivin · · Score: 1

      Resorting to thievery and lawlessness, whatever the cause, is morally repugnant.

      The only thing more morally repugnant is letting people die, especially when done by the government.

      Dinivin

    21. Re:This is not a good trend to cheer. by cpt+kangarooski · · Score: 2, Insightful

      Patents are not international, they are national. At best countries may choose to reciprocally recognize one anothers' patents, but they are not required to do so, and do still maintain their soverignty.

      On what grounds do you believe that patents have any existance internationally without some national recognition? Or to put it another way, if you started your own country somewhere, would you have to recognize the existance of patents everywhere? What's making you? Theats of violence if you don't aren't a particularly strong answer here, as that would mean the patent has no force aside from the military force of those who wish it to be enforced. Gimme something better - I dare you.

      --
      -- This and all my posts are in the public domain. I am a lawyer. I am not your lawyer, and this is not legal advice.
    22. Re:This is not a good trend to cheer. by sql*kitten · · Score: 2
      They are covering all the equipment, raw materials and labor.


      Those costs are trivial compared to the cost of the research and development it costs to create a new drug.

      If the Brazilian government were really interested in the health of their people, why aren't they willing to fund their own R&D and develop their own drugs?

      And do you really suppose politicians, with their bodyguards and palatial state buildings care any more or less about "the poor" than any corporate CEO?

      This is no different from one country deciding it needs the resources of another - minerals, say - and simply sending their army to annex it. A classic example of this is Iraq invading Kuwait.

      This is a cynical attempt by the Brazilian government, who are facing elections ins a few months, incidentally, to ride the anti-corporate "trend" that seems to be popular at the moment.

    23. Re:This is not a good trend to cheer. by DCheesi · · Score: 1

      This brings up a good point regarding the sainthood of profit-seeking drug corporations. Everybody is talking about the need to pay them to encourage development of new drugs. This is certainly true for new treatments, but what incentive do they have to produce a cure? A cure only gets used once per person, while an AIDS patient getting treatment is a guaranteed source of income for several year at least.

      If we rely solely on the workings of modern capitalism to produce beneficial advancements, we are limiting the range of advancements to those that are profitable. But what if the best solution is not the one that produces the most profits? I'm not saying that profit incentive should be eliminated entirely; we all know that doesn't work. But we need to stop treating free-market forces as a perfect mechanism that will solve everything. Government and society need to know when to step in, to promote the greater good; that's exactly what Brazil is doing in this situation.

    24. Re:This is not a good trend to cheer. by gazbo · · Score: 1

      So, explain that to the 3-year kid that got AIDS from his mom. Will somebody please think of the children? -1 Offtopic

    25. Re:This is not a good trend to cheer. by Remote · · Score: 2

      Let me put this Embraer x Bombardier case in perspective: Aircraft industry is highly dependent on R&D investment. You can't think of designing a jetliner with less than 200 million USD. Companies do not have this cash, as a rule, so they seek credit. The problem is, banks charge different interest rates based on risk classification, which they do not assess themselves, rather rely on classification from specialized firms, such as Moody and Standard&Poors. Countries are risk-rated too, and it is an unwritten rule in the financial market that a company can't obtain an international rating higher than that of the country in which it is based. Coutry rates issued by different firms are very close, not nominally, but in what they indicate the risk is.



      Canada, I think, is rated AAA by S&P. Brazil delayed some payments to some banks in the late 70's, and has been showing a small trade surplus, sometimes even deficit in the latetr years. There are other issue, but these two have a big weight. So, Brazil is rated BB+, IIRC. This means Bombardier can obtain credit at something like 500 base points below what Embraer can. And the companies themselves are not too risky; the segment in which they compete, middle size jatliners (80-130 pass.) was highly neglected in the past, with Boeing, Airbus, MD focusing on big planes and others (Cessna, LearJet, etc.) focusing on small planes. When Fokker closed, this marked had very few contenders, so it's kind of up for grabs. What the Brazilian government did was to "cover" this difference in spread.



      The beef case, now, that was ridiculous. During the mad-cow disease outburst in Europe, Canadian authorities closed beef imports from Brazil as a safety measure. It was right after the Bombardier case.

    26. Re:This is not a good trend to cheer. by Rupert · · Score: 2

      This is no different from one country deciding it needs the resources of another - minerals, say - and simply sending their army to annex it. A classic example of this is Iraq invading Kuwait.

      Except no-one is being killed. In fact, quite the opposite. This US-imposed tax on knowledge is more like a famous UK-imposed tax on tea, and Brazilians are merely exercising the Boston option.

      --

      --
      E_NOSIG
    27. Re:This is not a good trend to cheer. by Rudeboy777 · · Score: 2

      Emotional pulls make for poor arguments ("Won't someone please think of the children?!")

      Are you a robot? Or just a CEO? "Won't someone please think of the children?" is silly when you don't want your kid to see a boob or hear the word 'Fuck' but watching him/her die innocently is a completely different can of worms.

      --

      From hell's heart I fstab at /dev/hdc

    28. Re:This is not a good trend to cheer. by GrayArea · · Score: 1

      You can't expect people desperate for the lives of millions of their fellow citizens to uphold international patent laws for the sake of intellectual property, regardless of whether you believe in the validity of the phrase or not. Do you expect Brazil or another country who doesn't have the technological and/or financial means to come up with a cure to AIDS to be dependent on global pharmaceutical industry's idea of what its profit margins should be? It may be difficult to put a fair price on so called intellectual property, but I would say the lives of millions of people, or even the prospect of easing their agony just a bit, is priceless.

      --
      "The deluded are always filled with absolutes. The rest of us have to live with ambiguity." - Aristoi, Walter Jon Willia
    29. Re:This is not a good trend to cheer. by bartok · · Score: 1

      As long as the US alone enforces it's own patent laws in it's own country, there will be enough incentive to develop new medecin. The US alone probably generates more sales money for these companies that all of south america and africa.

    30. Re:This is not a good trend to cheer. by david42 · · Score: 1

      Extortion of the sick is morally repugnant. Especially if done by a corporation in the name of profit.

      --
      wugga wugga
    31. Re:This is not a good trend to cheer. by Rupert · · Score: 2

      Very true. I almost brought up this point myself, but didn't want it to detract from the main point of my post. If there's any justice [*] you will be moderated up.

      [*] or at the very least an interruption in the moderators' crack supply.

      --

      --
      E_NOSIG
    32. Re:This is not a good trend to cheer. by Auckerman · · Score: 2
      I don't care how much it costs to make a drug (research and all), if you can save (or extend) just one human life by breaking a patent, just one life, you are totally justified in breaking the patent. The lives of our fellow humans are bigger than patent laws. They are bigger and the WTO. They are the most important thing one can care about. Now let's address the points one by one.


      "1. Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference. (see South Africa's example - do it or we take your companies assests)"


      If a the only reasonable way a person can feed their family is by stealing, they are totally morally justified by doing so. If the only reasonable way a POOR country can get drugs to help their citizens live productive lives is by breaking patents they are morally justified in doing so.


      "2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement)."


      Asolutely silly. There will always be profit in creating drugs. The question is whether or not the company wants to price gauge. All you have to do is look at the difference between the cost of drugs in the US and in Canada. They charge what they beleive they can get with their monolopy power.


      "3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good""


      It is not a question of public good. It is a question of human life. Noone has the right to put a price on YOUR right to live. They have a right to reasonable compensation, if possible.


      "4. Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces."


      Totally 100% irrelevent. In this case said country would just produce the drugs themselves after visiting the US and see what the drug is.


      "When do we stop? Who can judge what is a fair price for something? Who can judge what can fairly be patented?"


      begin rant


      In the case of saving lives, Brazil is totally justified. We stop when drug companies stop trying to hold the lives of people hostage with high prices. We stop when people can get affordable health care. Do you realize how modern AIDS drugs were developed? Researchers when to South America and got bark, branches, plants, etc from their forests, came back to the US and tested how they affected HIV. At one point in the mid-eighties a drug was found to inhibit HIV production and cause it to recede (for a time). They went back into the forest and the tree they got it from was gone due to clear cutting. Then the inhibitors arrived, helped, then HIV learned to resist them. They then tried to produce NATURALLY OCCURING CHEMICALS in the lab and got a patent. Patent on what?!?!?! A process? The way i see things, Brazil has a RIGHT to HIV drugs since many if not all of them came from their forests....



      /end rant

      --

      Burn Hollywood Burn
    33. Re:This is not a good trend to cheer. by SJS · · Score: 1
      1. Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference. (see South Africa's example - do it or we take your companies assests)
      Apparently you didn't read the article. Let me quote:
      In a statement, ministry officials said the country would issue a compulsory license to make the drug, and domestic production would begin Friday. The drug would not be distributed until early next year.
      The swiss company will get money. It's not like Brazil is stealing -- only resisting being raped for a foreign corporation.

      Next:

      2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement).
      IIRC, Brazil was pissed that not all countries were charged the same price. This is a matter of resisting the practice of charging what the market will bear [Caveat Emptor is a necessary philosophy for a buyer, but an evil one for the seller] -- Roche wasn't behaving ethically towards Brazil, so there's reason to "rightfully fear" losing anything. They [Roche]weren't in the right!

      Next:

      3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"
      The problem with this is? If you abuse the IP laws, then you should be penalized by having that IP placed in the public domain. Brazil isn't going that far; commendable restraint, I think.

      Next:

      4. Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces.
      That just means that there is more compulsory licensing -- and if the company doesn't maintain a presence in those "hostile" countries, then someone in those countries can patent "external" inventions independently, locally. It is far more sensible for companies to try to avoid making countries "hostile" -- hopefully by some means other than corruption of high officials.

      When do we stop? Who can judge what is a fair price for something? Who can judge what can fairly be patented?
      Presumably we apply some sort of good sense metric. Who can judge what is a fair price? Well, look at what is being charged elsewhere, and compare, and then look at the markup. If you're getting raped, then the price you're being charged is obviously not fair.

      As for who can judge what can be fairly patented -- if you can't come up with an answer to that, then you shouldn't be allowing patents, full stop. Personally, I feel that mathematics, biology, and physics should not be patentable; only engineering can be patented: you build a device that (a) is demonstrably new, innovative, or a significant improvement, and (b) you can provide a working model to a patent office, with instructions that allow for duplication. Anything less is just a trade secret dressed up in funny clothes.

      All IP, by nature, is in the public domain. We want inventions -- and the ability to recreate them -- made public, so we grant a limited monopoly to the inventors. Patents aren't an enforcement of the right of an inventor to make money, they're an assurance that the Public will be able to recreate an invention and use it without restriction in exchange for a slight delay for the inventor to make his bit. Abuse of that limited monopoly voids the social contract.

      Brazil is being more than fair.

      --
      Pick One: http://www-rohan.sdsu.edu/~stremler/sigs/sigs.html (Note - disable Javascript first!)
    34. Re:This is not a good trend to cheer. by Stephan+Schulz · · Score: 1
      The clear argument is, that it is wrong to steal, even if it saves someone's life. Period.


      Uhh....moral absolutism. I'm impressed. So I am not allowed to take ("steal") a rope to throw it to someone drowning? I am a criminal ("tresspassing") if I enter a burning building to save a child? And if I have to batter down the door ("damaging property") I'm on my third strike and go to prison for live?


      Real world situations are nearly always to complex to naively apply simple, unconditional rules to evaluate them.

      --

      Stephan

    35. Re:This is not a good trend to cheer. by frosh · · Score: 1

      Apparently people are willing to allow those with the guns to do it, and not realize its the first step to losing their own rights.

      Apparently you don't realize that the only reason there is IP at all is that people with guns say so. Without the threat of Police / Jail / Force, why would anyone agree that someone else can OWN an IDEA, or a STORYBOOK, or a piece of DNA, and charge everyone else to use it. Intellectual property is the LAW, but that doesn't mean it's RIGHT, and it is not immoral to break an unjust law.

      -------
      I don't wantto be an old man anymore...

    36. Re:This is not a good trend to cheer. by bogado · · Score: 1

      If the Brazilian government were really interested in the health of their people, why aren't they willing to fund their own R&D and develop their own drugs?

      Brasil did exactly that, the goverment pays for the research. The institute that sucessfuly made the drug (fiocruz if I am not mistaken) is funded by the goverment. The best universities of Brasil are funded by the goverment and are free.

      And this is not a election public trick, since there are many more efective ways of getting votes here that would not make uncle sun and the corporate world mad at the goverment. People in Brazil forget very fast, and the election are only in the next year. This news will be forgotten here by all except for those that benefit from the drugs by the next month or so. Apart from the fact that this news didn't get into the first page of any paper today.

      The Brasilian goverment has to reduce it's deficity by large amounts to make the demands of the IMF. It already have the police to treat AIDS pacients, so this is not a new trend. It pays millions of dolars to pay the royalty, and the international public already aplauded Brasil in a similar incident before. Just add 1+1.

      --
      []'s Victor Bogado da Silva Lins

      ^[:wq

    37. Re:This is not a good trend to cheer. by aaronl · · Score: 1

      > I do believe that international patent law
      > should be different, but believing that a law
      > should be different is never a good reason to
      > break it.

      In all honesty, the existence of international patent law is bullshit. It's entangling countries that used to be independant into these larger multi-national federal governments.

      And believeing a law is wrong or should be changed is a rather good reason to break it. When you realize that you'll never change a law by working in the system, the only way to change it is to break it. Maybe you'll have to break even more laws in the process of changing that one bad law.

      The US wouldn't exist if Brits didn't break English laws, for example. And when laws get as ludicrous as many are today, things that were legal yesterday suddenly become illegal, and you may not even know it happened.

      If you want a prime example of this in history, look at the US's Prohibition. If you want an example of what stupid laws cause in action, look at the US's "[Illegal] War on Drugs".

      I think Brazil should have attempted to pay to license the patent, but if the pharmaseutical company was asking for a ridiculous amount of money for it, then they already got what they deserve. Used to be that people would do research to better humanity, and sometimes even give it away! Hope this particular drug company isn't the one that cures HIV or cancer. Most of the people afflicted with it would die because they couldn't cough up 80,000$ per treatment the drug companies want.

    38. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0
      Yes, the drug companies need to recover their costs (and make a profit). An AIDS treatment will sell like hot cakes right up until a cure is discovered. Moderate, non-prejudicial licence fees will give them that.

      What an ignorant statement.

      What's moderate? There is no way to judge that objectively. Let's say Roche plans to recoup their costs for Nelfinavir (and R&D and associated failures, can't forget those) over 4 years, but a CURE is discovered in 1.5 years. What then? Do you hold back the cure until the cost to Roche is paid back? No? Do you pay Roche? How much do you pay them? Who gets to pay? The people who have been paying the full price all along? The people who got off cheap?

      Who's going to work for a cure if there is the increased possiblility of nations declaring an emergency and nationalizing the formula?

    39. Re:This is not a good trend to cheer. by SlippyToad · · Score: 2
      This is no different from one country deciding it needs the resources of another - minerals, say - and simply sending their army to annex it. A classic example of this is Iraq invading Kuwait.

      Well, it's only different when you realize that no one was killed, no land was taken, no national boundaries were violated, and nothing was "lost" except money that wasn't going to get paid to the drug companies in the first place. Other than that it's a perfectly valid analogy.

      What this really does is reveal the artificial nature of so-called "intellectual property." How ideas can only be granted property status by a removal of the right to use them, and only by a public that consents to it. Brazil just so happens to not be bound by US patent law.

      --
      One day I feel I'm ahead of the wheel / the next it's rolling over me / I can get back on / I can get back on
    40. Re:This is not a good trend to cheer. by jafac · · Score: 2

      this is not a new trend.

      It is old, and has been going on as long as humanity has had the use of language as a tool to twist meaning.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    41. Re:This is not a good trend to cheer. by Manax · · Score: 1
      Lesser evil, yes, but what you are saying is that the ends justify the means. It doesn't matter what attrocities you or your government performs, if the results are worth it...

      In this case, it is theft. But if stealing from tens of thousands of people is okay to help prolong some people's lives, what isn't okay? What is the rule you use to decide? What is TOO wrong to do?

      For instance, let's say Brazil is effectively stealing from 100k people (not unreasonable, "the company" isn't the only one affected by this, all the employees, stockholders (which very well could include you and I, participate in a 401k plan?) and others will potentially feel this) to help prolong/improve the lives of 500K people (I'm just making this up, I don't know actual numbers for any of this, but I'm making a point), you claim this is okay and laudable. Is it okay to steal $10 from each of those people? $100? $5000? What if Brazil had to physically injure each one to help the supposed 500k? Would it be okay to kill 10 people to help prolong/improve the lives of those 500K people?

      Let me also state that while the use of IP that someone else owns is stealing, there is a distinction between potential harm and actual harm, although there certainly is actual harm involved. (The distinction between actual/potential is most clear with software piracy...)

      --
      "Why should I be content to simply live in this world, when I, as a human being, can CREATE it?" - Oertel
    42. Re:This is not a good trend to cheer. by sql*kitten · · Score: 2

      no national boundaries were violated

      What this really does is reveal the artificial nature of so-called "intellectual property."

      Intellectual property is as much "property" as national boundaries are "boundaries".

    43. Re:This is not a good trend to cheer. by Aqualung · · Score: 1

      Eww... a utilitarian.

      If a the only reasonable way a person can feed their family is by stealing, they are totally morally justified by doing so.

      Ahhh, but when is enough enough? Should he steal enough for a loaf of bread, or a dinner for seven at a five-star restaurant? What about toothpaste, for his families' dental health? Cough medicine? At what standard of living does stealing become "bad" again? What if he steals from people in even worse situations than he and his family are in? You're vastly oversimplifying the situation here, and these examples, chock-full of idealistic situations don't really apply to real life.

      --

      - Dave
    44. Re:This is not a good trend to cheer. by mickeyreznor · · Score: 1
      I do believe that international patent law should be different, but believing that a law should be different is never a good reason to break it.

      that's all the more reason to break it. sometimes lobbying and reasoning only get you so far. sometimes you just gotta say "fuck you, i won't do what you tell me." Otherwise, you just get stuck with dumb laws, and they will never get changed.

    45. Re:This is not a good trend to cheer. by mimbleton · · Score: 1

      "This US-imposed tax on knowledge is more like a famous UK-imposed tax on tea"

      What a piece of crap.
      US-imposed tax is there to recoup huge costs of R&D.
      There is NO limitation on R&D - anyone can come up with their own drugs.

    46. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0
      1. Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference.

      I say good for Brazil. Go for it. Fuck the international law that only serves multinational companies. A law that does not serve the people but a corporation is not a law worth having.

      (see South Africa's example - do it or we take your companies assests)

      So it is really all about corporations, isn't it. Who gets to make the most money. And human beings are just pawns being plaid in this macabre game of chess. I don't like it. If anything can turn the pendulum in this regard it should be applauded.

      2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement).

      The possibility?! Jesus Fucking Christ, what planet you live on? People are dying today! They need help today. And you want to sit on your fat ass and talk about possibilities!!

      3. Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"

      And this is bad because...? Oh, it would probably mean we would have to live in a more humane world instead of the corporate driven one. Yes, that would be a very bad thing.

      4. Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces.

      So you mean less American corporations stealing my money? Again, I fail to see what is so bad about this.

    47. Re:This is not a good trend to cheer. by mimbleton · · Score: 1

      Don't tell me you are that stupid to believe that companies will continue making products that costs millions to develop to have someone grab their research and start selling it for 1/10 ?

    48. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0

      > "country refuses to pay a fair price for drugs to save its own people"

      But what is a fair price when one company has a worldwide monopoly on its production?

      Suppose you have a disease and I have the rights to the only cure. You can have it for ten billion dollars. Is that fair?

      Brazil already came to agreements with other drug companies, this is just a matter of one company being particularly reticent.

      > (see South Africa's example - do it or we take your companies assests)

      Hey, it's called sovereignty. If SA goes ahead and does this, they just run the risk of losing foreign investment in the future.

      Brazil is willing to pay other drug manufacturers, I don't think that their action toward one company is going to dissuade every other group.

      > 2. Reduces the possibility of region specific drugs NOT being developed because companies
      > rightfully fear losing all investment.

      Um, if countries can't pay for the drugs today, why would drug companies want to make drugs for such 'region-specific' diseases anyway?

      > 3. Raises spectre of loss of intellectual property on other levels, and more and more are
      > confiscated for the "public good"

      See eminent domain. This is one of the established powers of government.
      Yes, we can knock down your house to build a freeway. But we have to compensate you for it.

      Brazil has reached agreements with the other companies on what is a fair compensation.

      > 4. Increases the likelyhood of similar industries leaving "hostile" countries furthering
      > the problem that country faces.

      This already happens and has nothing to do with patents.

    49. Re:This is not a good trend to cheer. by ink · · Score: 2
      This is some of the most annoying rhetorics I've ever heard on Slashdot. .... This is some of the most annoying rhetorics I've ever heard on Slashdot.


      And that is another example of annoying rhetoric. How many people die from cars every year when we could walk? How many people die from coal pollution when nuclear power would be much cleaner? How many lives could be saved if the government mandated that we all wore plastic bubbles with every safety system known installed? Using the value of life to justify anything and everything is just as tiresome as listening to the rants about how all companies are evil and how research can be compensated with some other nebulous means. I think the current state of affairs demonstrates which system produces the most cures and (as a result) the most net benefit to society as a whole, as a world, as a people.


      That Brazil wants to side-step this process is disturbing. How many companies are going to refuse to publish their drug information for fear that Japan and Brazil will simply re-create the drugs? How many will stop talking to those countries as a result? And the real question: How many drugs has Brazil given to the world to justify their actions, and how many of their people will be hurt by their government's short-sighted action?

      --
      The wheel is turning, but the hamster is dead.
    50. Re:This is not a good trend to cheer. by mimbleton · · Score: 1

      No, but if somebody starts treating any sort of problem as an emergency giving him right to do whatever they want,then you have a much greater problem.

    51. Re:This is not a good trend to cheer. by SlippyToad · · Score: 1
      This is some of the most annoying rhetorics I've ever heard on Slashdot... If we let kids watch horror movies, how long until they start watching porn and God(tm) knows what else? If we let marijuana go legal (for health reasons, of course), how long before we legalize cocaine?

      Look, if I give you an inch, how long before you'll take a mile? Let's do the math: 1 inch per day x 356 days per year is 365 / 12 = 30 (rounded off) inches per year. Therefore at that rate, it will take you 63360 / 30 = 2112 years (and some) to take a mile from me. The last track on Rush's "2112" is "Something for Nothing," which explicitly states that you can't have your freedom for free, and if you want that mile from me, you'll have to take it an inch at a time.

      Sorry, I was just letting my mind wander down a slippery slope. Pardon me.

      --
      One day I feel I'm ahead of the wheel / the next it's rolling over me / I can get back on / I can get back on
    52. Re:This is not a good trend to cheer. by Waffle+Iron · · Score: 2
      The clear argument is, that it is wrong to
      steal, even if it saves someone's life. Period.

      Congratulations, sir. You have just made the single
      most moronic assertion ever posted on /.
      Quite an accomplishment.

    53. Re:This is not a good trend to cheer. by StenD · · Score: 2
      This is the new trend, government are going to take what they want and justify it in any shape or form. While they start off doing this with the cover of "saving lives" how long before it becomes anything they want?
      Well, in the U.S. at least, this is hardly a "new trend". The blanket justification taking or controlling whatever they want is that it's "for the children". Whenever you hear a politician say that, or it's relative "it's for the seniors", hold onto your wallet and your liberties.
      Apparently people are willing to allow those with the guns to do it, and not realize its the first step to losing their own rights.
      No, the first step to losing your own rights is to permit yourself to be disarmed. That's why those who honestly believe that they know better how you should be living your life than you do are so interested in curtailing private ownership of small arms, and are so distressed that the Bush administration opposes those activities. The ostensible excuse for this is that it will reduce armed conflicts, despite documentation that less than 1% of small arms are held by insurgents. The true objective isn't to prevent armed conflict, but to prevent you from being able to live your own life.
    54. Re:This is not a good trend to cheer. by mimbleton · · Score: 1

      "Boeing, for example, gets billions to develop military craft"

      Well, these military crafts are the best in the world so what is your point here ?
      We get what we ordered.

    55. Re:This is not a good trend to cheer. by krlynch · · Score: 2

      Public good means that ALL OF US GET RICH, and there's more to riches than money.

      There sure is... so I think that from now on, following Brazil's lead, the US should outlaw and confiscate all sorts of things. Like your car. It just pollutes the environment, and makes the streets crowded. We'd certainly be better off without pollution. And your computer. You can't have that anymore either because it uses so much electricity, which just causes pollution. And while we're at it, all that software your wrote under the GPL... we'll just take away the copyright protection, because the public would be better off if that software were public domain and Microsoft could use it to improve the software everyone else has chosen to use. And tuition to public colleges is now going to reflect the actual cost of educating a student, because the public good will be enhanced by not having to pay for the discrepancy for people that are just going to get rich in the future anyway. And you now have to serve a mandatory term of army service in the US. We've seen the light, and just like most other countries in the world, we think that the public good will be much enhanced by requiring all our citizens to serve in uniform. And police officers, teachers, doctors, and garbage men will now be compelled to work for free, because the public good would be much enhanced by having free protection from criminals and completely free health care and education through the end of high school. And those criminals? Well, they will now all be executed when caught, because that will be so much cheaper and easier for society than dealing with expensive trials and the dangers of recidivism.

      I could go on listing things that would be in the "public good" that most people posting are likely to disagree with (I disagree with all of them, actually). I've made my point, that things which on the surface look like they are in the "public good" are not necessarily so when a full analysis has been done. And since one hasn't been done in this case, to claim that the "taking" of this patent IS in the public interest is both unsupportable and intellectually dishonest, both to the Brazilian citizens affected by AIDS and all the rest of us who may end up suffering in the future because of it. As for me, I'm going to withhold judgement on this issue until then.... but I won't be holding my breath, because I don't think we'll be seeing that analysis done anytime soon.

    56. Re:This is not a good trend to cheer. by clink · · Score: 1

      So if were to steal your house and all of your possesions and sell them to raise money so I can buy something that will save my child's life, you're ok with that?

      Thankyou, drive through.

    57. Re:This is not a good trend to cheer. by clink · · Score: 1

      Where does it end though? If you can steal IP to save AIDS patients then surely I can steal all your stuff to pay for my heart transplant, right?

    58. Re:This is not a good trend to cheer. by WNight · · Score: 2

      If breaking a bad law is never justified, what do you do when big companies literally buy laws ("donations" to politicians) and you'll *never* have any say in the law.

      I mean, some laws you'll have a say in, and be overruled. Some laws you'll never get a say in, because if it ever comes to a vote, they've made sure it can't lose.

      If you aren't justified in breaking a law, what can you do?

    59. Re:This is not a good trend to cheer. by jafac · · Score: 2

      this sounds like the classic psychological test-question for moral development; would you steal a drug needed to save your wife's life if you couldn't afford it?

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    60. Re:This is not a good trend to cheer. by dswan69 · · Score: 1
      "country refuses to pay a fair price for drugs to save its own people"


      If the day should ever come where pharmaceutical companies charge a fair price.


      Want a story that is similar, but on a more "person" level. White farmers losing their property in Zimbabwe, because its not fair that they have it.


      Completely spurious - there isn't even any sort of remote resemblance between the two situations.


      Reduces the possibility of region specific drugs NOT being developed


      You mean less than the zero chance there was before?


      Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"


      Many things are done in the name of the public good, some beneficial, others not. The South African court case against these greedy multinationals was a bold and brave move - why do you think the pharmaceutical industry settled? Because every day more and more evidence was produced that clearly demonstrated that these corporations are lying, thieving scum who are more than happy to actively assist in bringing about the death of millions rather than do the right thing - they even admit that they make almost no money from the third world anyway so they really had nothing to lose, but they did hope the SA government would chicken out and they would be able to bleed dry not only them, but Brazil and numerous other poorer nations.



      These are not nice people and they are driven by pure greed. What does it matter if a few hundred million third world people?

    61. Re:This is not a good trend to cheer. by caio · · Score: 2, Informative

      One point to keep in mind:

      The Brazilian government gives all AIDS medication for free to anyone needing it.

    62. Re:This is not a good trend to cheer. by krlynch · · Score: 2

      If a the only reasonable way a person can feed their family is by stealing, they are totally morally justified by doing so.

      Unless by so doing, you condemn others to suffering. And how far does this argument go? Am I justified in stealing my neighbor's house because my family doesn't have a place to live? And let's be blunt here: Brazil isn't "saving lives" by making "stealing" this patent. These people are, unfortunately, already condemned to an early death. These drugs may help push it off a few years, but this isn't a cure. Are you still justified in stealing food from your neighbor if you are going to be dead in a few hours from the time bomb strapped to your waist? (okay, ridiculous example, but I hope you get my point). I don't think the moral and ethical issues are as clear cut as you make them out to be.

      Asolutely silly. There will always be profit in creating drugs.

      It is absolutely silly to make such a blanket statement. There are dozens of drugs that have been discovered but are not made because likely to be unprofitable. There are a number of known birth control drugs that are more effective than those currently marketed, but are not sold because they will not be profitable. The odds of a MALE birth control pill being sold are very small, as the profits are likely not there. The costs of R&D on new antibiotics are astronomical and little R&D is being done because the likelihood of recouping that cost is so low. To expect that any given drug will automatically be profitable and therefore will be made is as silly as claiming that all drugs will be unprofitable without patent protection.

      No one has the right to put a price on YOUR right to live.

      Again, you are incorrect. This happens all the time, and I don't hear anyone complaining about it. We could build a car that no one is ever killed in, but it would be so expensive it would bankrupt the companies making it and the people buying it. We don't expect houses to be made out of fire-proof materials because the cost would be astronomical, but that would save lives as well. Society has realized that protecting all lives at all times is not only impossible, but also not in the general interests of the public at large. And, in my opinion, that is the only rational path to take. But doing so implicitly puts a dollar (or yen or ruble....) value on the lives lost as a result of NOT spending the money. The real question to ask is when and where do be set the bar, not if one is set. If saving a single life costs $10 more per car, is that worth it? what about $100? $1000? $10000? When does it become unrealistic to ask people to spend that money? The answers to the real questions are much harder to arrive at than the blanket statement that "you can't put a value on a human life", but in the end they are much more important.

      The way i see things, Brazil has a RIGHT to HIV drugs since many if not all of them came from their forests....

      And the way other people see it, the pharmaceutical companies have a RIGHT to the patent protection because most, if not all, of the WORK to find, understand, purify, and produce the drugs in a form that is both safe and effective came from the money of the companies and the work of their employees. Why do they have inherently less "right" to their discoveries and the fruits of their hard work? Before you answer that, stop and think about where else the answer may apply. What about the programmer who wants to "protect" his work under the GPL.... why should he have any protection for his work, since the likelihood is VERY high that he is just copying the results of someone else (either their theoretical work, or an actual product)? Why shouldn't that work be required to be in the public domain? And why should police officers be paid more than minimum wage? Don't I, under your reasoning, have a "right" to protection of my life and property, and wouldn't that "right" be enhanced by hiring more police at lower cost? I could go on, but I won't. I would just urge you to realize that the issues you are talking about are not so simple as you are arguing that they are....

    63. Re:This is not a good trend to cheer. by sgups · · Score: 1

      CIPLA is the Bombay, India based firm providing the cheap costs. The google search page on CIPLA gave this list

      --
      Democratic USA - Government of the corporations, by the Corporations, for the corporations.
    64. Re:This is not a good trend to cheer. by Stephan+Schulz · · Score: 1
      No, but if somebody starts treating any sort of problem as an emergency giving him right to do whatever they want,then you have a much greater problem.

      Right. But this is not "somebody", it is an elected gouvernment of a large nation. And it is not "any sort of problem", but an epidemic. There are roughly 200000 people with AIDS in Brazil. Assuming an average livespan of 3 years for untreated clinical AIDS (we are not talking about infection here, we are talking about people with symptoms), the death toll is approximately equivalent to one Oklahoma City bombing every day. Add to this the additional burden of caring the sick.

      I consider this a fairly grave emergency.

      --

      Stephan

    65. Re:This is not a good trend to cheer. by Anonymous Coward · · Score: 0

      This is the new trend, government are going to take what they want and justify it in any shape or form. While they start off doing this with the cover of "saving lives" how long before it becomes anything they want?

      It works like this for years you know, especially in Europe and France. WTF is the US patent for them? they don't care and don't give a fsck

    66. Re:This is not a good trend to cheer. by Stephan+Schulz · · Score: 1
      Where does it end though? If you can steal IP to save AIDS patients then surely I can steal all your stuff to pay for my heart transplant, right?

      You might possibly benefit from learning a little bit about logical arguments.

      If you can lift a can of beer, then surely you can single-handedly raise the Titanic. Doesn't this sound idiotic? It's the same construction you used...

      It ends somewhere in the middle, as nearly always. Note that e.g. they are not taking anything from Roche but a small part of the possible future earnings. Note also that on the other hand we have the continued life and productivity of a couple of hundred thousand people.

      By the way, I am giving away most of my intellectual property anyways. You can get it from the E theorem prover page. Hope it helps you in getting a transplant.

      --

      Stephan

    67. Re:This is not a good trend to cheer. by gorilla · · Score: 2
      This is no different from one country deciding it needs the resources of another - minerals, say - and simply sending their army to annex it. A classic example of this is Iraq invading Kuwait.

      A better example is the US invading Panama just when the canal lease was about to expire.

    68. Re:This is not a good trend to cheer. by SlippyToad · · Score: 2
      Don't tell me you are that stupid to believe that companies will continue making products that costs millions to develop

      Well, since you put it that way, I must be.

      Two questions I keep posting, and I have yet to see them answered:

      1. How much does it really cost a company to make a drug? I know where I work, estimates of what it "costs" do to something are fictitious at best. The answer would of course dictate whether I thought the public would pay for the research on drugs that were really important.

      2. Aside from the occasional life-saving AIDS treatment (note I don't use the word "cure"), what drugs have these companies really produced, lately, using this supposedly irreplacable intellectual property reward system, that have been of long-term use to society, or humanity? Prozac? Rogaine? Viagra?

      I am increasingly skeptical of this system as something worth preserving. Drugs got developed before giant pharmacutical companies existed. Cures were found for great diseases. The motivation can be, and should be, something other than cold hard cash.

      --
      One day I feel I'm ahead of the wheel / the next it's rolling over me / I can get back on / I can get back on
    69. Re:This is not a good trend to cheer. by schporto · · Score: 2


      I'll throw out a couple responses. Using a few companies and their statements (while probably not 100% accurate these are SEC and FDA liable statements).


      • AstraZeneca Produces Nolvadex (used to prevent breast cancer), Seroquel (used to treat schizophrenia), and many others. Rougly spending $2 billion per year on research.
      • Bristol Myers Procuces Taxol (used to treat various cancers), Gloucophage (used to treat diabtes), Videx (used to treat HIV) amongst others. Rougly spending $2 billion per year on research.
      • Roche (yes the trigger for all this hoopla) Produces several cancer fighting drugs, many to fight heart disease, and many to fight various STDs. Spending roughly $2 billion per year on research.

      Do remeber these companies research tons of drugs and many turn out to be busts. Never showing any signs of efficacy. Or doing more harm then good. But roughly speaking say 2-5 drugs launches (actually selling to the public) per year. So on a year by year a rough guess is somewhere between $.4billion and $1billion. Although that guess doesn't take into account new indications for already developed drugs. Which would push the numbers up though.
      And yes drugs got developed before drug companies existed. But then again so did snakeoil. And worse. Then came the FDA (and MCA and all the other regulatory agencies). And now yes you could discover a great drug in your basement, but you couldn't do jack with it. Except try to sell it to these comapnies. Try to sell it to other people and go to jail. Try to actually manufacture it - go to jail. The public demanded oversight on the manufacture of drugs due to way to many people dying from taking them. The public got regulation. But with that regulation comes some restrictions.

      Besides I'd say that more and better drugs have been found by companies (which you hate) then by non-companies. Your turn. Prove it.


      -cpd
    70. Re:This is not a good trend to cheer. by Banjonardo · · Score: 1
      those in the western countries

      Western countries? And where is Brazil? Asia?

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

    71. Re:This is not a good trend to cheer. by Banjonardo · · Score: 1
      short-sighted?

      I don't think so. It was a thought-out choice. Simply put, the lives of the many (i should say few, but there are a lot) outweighed the future inconveniences of the whole. And I agree. I am Brasilian. A lot of my family are M.D.s, and all of them are somehow involved in treating AIDS patients. What really kills me is looking at the picture in my uncle's refrigerator and seeing him with some patients: 8 toddlers, all with AIDS.

      What do they have to do with patents, and money, and effort?

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

    72. Re:This is not a good trend to cheer. by SlippyToad · · Score: 2
      Gloucophage

      Just a side note: I was on gluc until a couple of months ago. I know lots of people who are on it. Not sure what it was doing for me, but I was able to reproduce the effects of the drug by changing what I ate and exercising more frequently. My point is that yes some of these drugs are revolutionary, but some of them appear to be little better than snake oil. I had to change doctors to find one who would agree to treat me without the glucophage. BM puts out several variants on gluc, most of which are just changes in the delivery mechanism. They expect to make billions, I'm sure. When their patent expires, they'll probably do their best to discredit their former glorious advance and go to another, incrementally more effective drug. I strongly suspect, because of my experiences, that doctors are not encouraged to find other ways to treat illnesses because of incentives from the drug companies. It's hard to find one who actually looks at what's wrong with me and advises a treatment beyond just giving me a pill. Another example: I had a doctor tell me, with a straight face, that I had a virus and in the same breath prescribe an antibiotic for it. I went home and threw the prescription away and changed doctors. Read up on the antibiotic crisis lately? There's an example of a self-devouring industry that shouldn't exist in the first place. If our so-called medical establishment didn't hand the fucking things out like candy our immune systems wouldn't be so weak . . .

      Besides I'd say that more and better drugs have been found by companies (which you hate) then by non-companies.

      Your turn. Prove it.

      My turn to what? Yes these companies spent so much in hard dollars during these years. Did that money go to research, or did it go to executive bonuses and other bullshit? Is there any way to tell? Large companies waste money in all sorts of creative ways. Every one I've ever been at fudged costs and documentation out the ass. I remain skeptical of both the supposed "investment" that goes into creating these, and the rewards we are recieving thereby. And as I discover more about how the drug industry gets their leads in the first place (good ol' government funding there) I begin to suspect that, as usual, the public is being had. Saying I "hate" these "companies" is a simplistic way of putting it.

      --
      One day I feel I'm ahead of the wheel / the next it's rolling over me / I can get back on / I can get back on
    73. Re:This is not a good trend to cheer. by Banjonardo · · Score: 1
      Speaking of that "stealing food" thing, I was reminded of Les Miserables.

      Was Jean Valjean at fault for stealing bread to support 8 people? Hugo thinks not. He says that Jean was forced by society, which created these circumstances. What you think about this is your answer to the patent problem.

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

    74. Re:This is not a good trend to cheer. by mimbleton · · Score: 1

      "The motivation can be, and should be, something other than cold hard cash."

      Sorry, you are dreaming.
      People have tried system based on other values and all of them eventually degenerated into perverted and much more dangerous version of good, old "cold hard cash" society.
      It simply is not going to work. You are fighting against human nature.

    75. Re:This is not a good trend to cheer. by Hadean · · Score: 2

      >Using the value of life to justify anything and
      >everything is just as tiresome as listening to >the rants about how all companies are evil and
      >how research can be compensated with some other
      >nebulous means.

      Uh, did I say that all companies are evil? Not whatsoever. I stated a fact that many pharmaceutical companies care more about the bottom line then people's health. I believe that it should be that way - people's lives are more important then how many more million a company can make then another company. Anyways, there's no point in debating - you couldn't care about your neighbour's life, unless you had some monetary benefit coming from it, right? If you saw your brother in law's son (2 years old) dying of an almost incurable disease, but a company was charching more then your brother in law could afford, wouldn't you care for the person or would you say it's the company's right?

    76. Re:This is not a good trend to cheer. by Hadean · · Score: 2

      You're automatically assuming that I WILL take an inch from your every day... where do you get the proof that I would? Or do you just assume that if someone takes an inch, they'll automatically (thanks to human nature) take another one?

      Assuming things like that, as the saying goes, makes an ASS out of U and ME.

    77. Re:This is not a good trend to cheer. by vanicat · · Score: 1


      If the Brazilian government were really interested in the health of their people, why aren't they willing to fund their own R&D and develop their own drugs ?



      a little help to know why, just look the GDP per inhabitant

      • Brazil: 6 480 $ US (1997)
        USA: 27 821 $

      another question ?


      It's what really bug me in this discussion : all this people, living in rich country without seeming to know it. Hey, wake up, the inhabitant of rich country have something like more than 4 time the money of an inhabitant of the Brazil. And can i recall you that their exist country much poorer than that ?


      Brazil have a chance : they are sufficiently rich to product their own drug to sell them at a fair price, they would have been stupid to not do it.


      You want money to make research for drug ? ask to the rich. I mean us, the inhabitant of rich country

    78. Re:This is not a good trend to cheer. by ink · · Score: 1
      I don't think so. It was a thought-out choice. What really kills me is looking at the picture in my uncle's refrigerator and seeing him with some patients: 8 toddlers, all with AIDS.

      What do they have to do with patents, and money, and effort?

      About as much as my niece who died being run over by a truck, or my dead best friend in high school going over the guard rails on an icy road. If we banned cars they would both be safely here.

      Brazil wants the immediate benefits of this drug, but they are throwing their future away by doing so. I suppose we shouldn't be surprised, this is the same country that pays its debts by printing more money (again and again and again and again) and then wonders why inflation hits.

      My point is: On a whole, obeying patent restrictions will prodcue better healthcare for everyone in the long-run. Doing things like this is short-sighted and dangerous; perhaps just Brazil and Japan doing it isn't so bad, but if everyone starts doing it then it will hurt many more people than Brazil is saving by doing this.

      --
      The wheel is turning, but the hamster is dead.
    79. Re:This is not a good trend to cheer. by ink · · Score: 1
      I stated a fact that many pharmaceutical companies care more about the bottom line then people's health.

      I work in pharmaceutics. You are claiming that I care more about money than saving lives. My whole point is: WE ALL CARE MORE ABOUT OTHER THINGS THAN SAVING LIVES at certain points, and we balance things out; make choices. You obviously own a computer, wouldn't that money be better spent devoted to un-patented medical research? How about sending it to feed the poor? You obviously care more about money than lives (sarcasm).

      The good of the many outweighs the good of the few. It's in HMOs. It's in government-run health-care. It's in you. On an anecodtal basis (your nephew) there is no solution that will please everyone, there is always more that can be done at some greater expense; doing everything for everyone would cost us everything we have and condemn future technology to remain at current levels. Patents are the carrots that motivate greedy people to do good things. Take that away and we won't have anything in a short time.

      --
      The wheel is turning, but the hamster is dead.
    80. Re:This is not a good trend to cheer. by SEE · · Score: 2

      Panama was invaded nine years before the lease expired. The U.S. troops were openly welcomed by the Panamanian people, the U.S. troops left after a democratic governement was established, and the canal was turned over to Panama on schedule. There are no U.S. troops today in a democratic Panama that has soverign control over the Canal.

      The U.S. has done a lot of objectionable things in Latin America. The Panama coup de main in 1990 was not one of them.

    81. Re:This is not a good trend to cheer. by refactored · · Score: 1
      "country refuses to pay a fair price for drugs to save its own people"


      BALDERCRAP! How about people are dying?! How about people simply don't have the money!? Typical damn rich twit!

      OPEN YOUR HORRIBLE EYES AND SEE WHAT IS HAPPENING AROUND YOU FOR ONCE IN YOUR MISERABLE LIFE!

      Look beyond the neat fences of suburbia and see the facts for a change...

      • Many people simply don't have money or barely enough to live on.
      • People are actually dying of a very nasty disease.


      Aids is often a disease of poverty. You are far more likely to get it if you are poor, as your immune system is already compromised by malnutrition, stress and other diseases.
    82. Re:This is not a good trend to cheer. by Suicyco · · Score: 1


      Except that this is also American policy. Manifest Destiny... We have the utmost right to ursurp any nations sovereign rights for our own needs. I say fair is fair..

    83. Re:This is not a good trend to cheer. by merlin_jim · · Score: 1
      In response to all three replies (who all said basically the same thing):

      And believeing a law is wrong or should be changed is a rather good reason to break it. When you realize that you'll never change a law by working in the system, the only way to change it is to break it. Maybe you'll have to break even more laws in the process of changing that one bad law.

      Let me change my original statement:

      but believing that a law should be different is never a good reason to break it unless that law clearly and unequivocally impinges on basic human liberties

      Yeah, there's some ambiguity about what basic human liberties are, but most people can say without hesitation whether a particular rule or law clearly interfere with them. And patent law does not clearly interfere with liberty, unless you believe that information wants to be free... but then, that's the informations' freedom and not human freedom.

      Besides which, if it wanted to be free, why did someone pay so much money to develop it? Which brings me to an interesting point that bears on the original discussion... what if the enforceability of a patent is directly related to the amount of money spent to develop the patent? Not quite sure how exactly to make that work, but the basic idea is simple: patents exist to protect a company's or individual's investment in intellectual property, therefore the amount of protection is directly proportional to the amount of the investment.

      Hmm... have to come up with a system that rewards ingenuity as well. Having a miraculous idea at two in the morning that noone else will think of independantly for a hundred years ought to be protected as well... any suggestions? Sound like a good idea, at least in theory? Or am I just smoking crack tonight? :)

      --
      I am disrespectful to dirt! Can you see that I am serious?!
    84. Re:This is not a good trend to cheer. by slaida1 · · Score: 1
      Anyway we're going to see where this path takes us. Kinda interesting, isn't it? Are you going to weep over how matters used to be or look forward and try to grasp how differently all could be?

      So, Roches is learning some lesson here. They're thinking probably that "hmm, Brazil did this now and they and other nations too are probably going to continue their parctises. That means if we announce a life saving new drug, we might not get as much dough anymore. Maybe we should concentrate more on drugs wich only cure everyday annoyances."

      Other drug companies follow Roches's lead. So then governments hopefully wake to the situtation and start funding more universities' drug R&D and everybody's happy again! :D

      --
      Preserve old classics: copy your collection onto all hard drives.
    85. Re:This is not a good trend to cheer. by Banjonardo · · Score: 1
      First of all, the inflation problem today is *nothing* compared to the 250% a month of two decades ago.

      Second of all, it's a philosophical question: should the masses suffer later to save the few (though still many) now?

      I don't know. But the government thinks so.

      --

      -----

      Score 3? For what? Being wrong, at length? - smirkleton

  20. Money vs. Life by Psion · · Score: 1

    It's really easy to fall into the trap of justifying this theft as necessary to save lives, but the pharmaceuticals that worked on these products are now being deprived of money from these countries that would pay for the research that went into the product. Look, the expense of the research and regulatory compliance to create a new drug doesn't go away when the drug comes to market...it sometimes takes years for a pharmaceutical company to actually make a profit. With the actions of countries like Brazil, that payback will now take longer.

    I wonder how the looters will get other life-saving wonder-drugs when they've driven the big research companies out of business?

    1. Re:Money vs. Life by Sir_Real · · Score: 2

      WTF? The REASON Brasil had to produce their own drugs was because of the PRICE GOUGING these poor, nearly going out of business because of the big bad Brazillian thiefs, drug companies. They couldn't get a 40 margin out of Brazil, so they decided to let them rot and die. I'll never feel sorry for these heartless bastards.

    2. Re:Money vs. Life by Anonymous Coward · · Score: 0

      Taxes on the people often fund research at universities that is later part of the drug companies process that they patent.

      Maybe if drug companues stopped shooting tv comercials and pouring billions into marketing they might make profit faster.

    3. Re:Money vs. Life by Psion · · Score: 1

      Get real, Sir_Real!

      Roche claims that they already made discounts "close to those that the ministry is requesting" and has even donated medicine. They are hardly price gouging. PharmaCorps have bent over backwards to appease third world needs, stopping short only of bankrupting themselves. Yes the bottom line is important...but without it the companys go belly-up.

      Where would the Health Minister be today if Roche went out of business five years ago?

      The simple fact is that Jose Serra's actions were politically motivated -- just in time for elections next month!

  21. *sigh* by omarius · · Score: 3, Insightful
    This should make sick every one of you that has a Free* bone in their body. Drugs are inventions, as much as gadgets are inventions, and this is IP theft, plain and simple. If I spent a fortune researching and creating a drug, you bet I would be pissed if someone else started making my drug without my permission.

    I like the idea of saving people, and it would be hard to sanction or punish Brazil for doing this -- since the rest of the world would boo us off the planet. But this is wrong, people. Hell, in the long run, education will save a lot more people than this drug. This drug will not make Brazillians stop fucking each other or sharing needles or whatever it is that Brazillians do to get AIDS.

    But instead of educating and changing killer lifestyle habits, their government steals IP. This world is going to shit. But that's just MHO.

    And to be off topic for a second, those moderators who disagree with me may feel free to moderate me down as a troll for having an opinion (since that's what happened the last time I posted) -- but that won't make me less right. ;)

    -Omar
    *as in Libertarian free, not social-welfare-state free. >;)

    1. Re:*sigh* by cybrthng · · Score: 2
      I have to agree, there is a time and place for IP, but aids isn't that place.


      If you lived in a population where aids is of epidemic proportions but it costs so much to get vaccinated what would you do? Die so another company can profit?


      Sure the government should have licensed the medication, but on the other hand, the profiteering and money grubbing developers should have provided for brazil long before they needed to make this stance.


      Its ironic how we think IP in technology is different then IP in medicine. Why is it right for people to patent vacinations that could save your life, but it isn't right for someone to patent an interface that has no position of life or death?

    2. Re:*sigh* by iomud · · Score: 2, Insightful

      I hope you're reminded of this when someone dosen't help you when it isn't in their best interest. Life is not about constantly having leverage over someone else, freedom isn't about letting people die for their mistakes. People make mistakes it's the nature of being human. What do lifestyle habits matter to people of Africa who are suffering greatly, children who haven't made any "lifestyle habits" born into AIDS and pain and death. Your humble opinion isn't so humble because you obviously know what's best for everyone, if you're making the decisions I'm leaving town.

    3. Re:*sigh* by Thackeri · · Score: 1


      You seem to somehow think the Brazillian Government is just doing this and nothing else to combat AIDS. You're wrong - there is a whole program in place to combat the epidemic - education and treatment.


      I agree that this is IP theft and that inventors should recieve fair reward for their innovation but it's fairly clear that the Brazillian Government were attempting to negotiate on good faith with Roche, they'd already come to terms with other companies to reduce the price. With the state of the AIDS epidemic Roce would more than make back R&D costs.


      You have to remember that Brazil isn't a rich country like the US or the UK etc. They really can't afford to throw money at a problem to make it go away. They're not getting the drug for free either - they're saving 60% of the current cost.


      It's not an ideal solution but I really think companies who develope important drugs have a responsibility to the people their drugs treat - without their suffering they'd have no profits!

      --
      Better the pride that resides in a Citizen of the world, than the pride that divides when a colourful rag is unfurled
    4. Re:*sigh* by Saib0t · · Score: 1
      Don't you think that the companies who patented those medicines already got the development cost back as well as some extra billion dollars?

      I don't say patents are bad, but if the price those companies wanted for access to that patented technology wasn't too high, brazil would have probably paid for it...

      But instead of educating and changing killer lifestyle habits, their government steals IP. This world is going to shit. But that's just MHO.

      And what benefit would "changing people's habits" give to those already infected? On a side note, you can't change someone, the person has to change him/herself. Of course education helps, but throwing bazillion dollars at "Smoking causes cancer" doesn't prevent all smokers from smoking...

      Like you, this was only my opinion... (but unlike you, I won't get any moderation, just like my 20ish last posts or something ;-))

      --

      One shall speak only if what one has to say is more beautiful than silence
    5. Re:*sigh* by Drakantus · · Score: 2

      IP is more of a contractual agreement than a law. It's rather arbitrary and not really based on reality at all. If the citizens of Brazil never agreed to it, there isn't much reason for them to follow it.

      --
      I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    6. Re:*sigh* by partingshot · · Score: 1



      Of course your entire claim is based on the belief that there is such a thing as IP.

      Since your unlikely to read anything that is critical of your views, here is something from the same camp as you (libertarian):

      The Libertarian Case Against Intellectual Property Rights

      --
      Anonymous posts are filtered.
    7. Re:*sigh* by abdulwahid · · Score: 1

      When was it that medicine turned away from being something to heal the ill in society and turned to being a profitable business for making the richer even richer and the expense of the poor. It makes me sick that people in Brazil, or other places in the world, will die of diseases just becuase some hugh pharmacutical company want to make even more bucks.

      I wonder if you would be able to explain to an 8 year old Brazilian girl dying of AIDS why she can't have the medicine. Not because they can't make it...but because some rich people thousands of miles away want to become richer. There is nothing right about this and it is a twisted mind that feels coporate success and money is worth more than life and death.

      --
      perl -e 'print $i=pack(c5, (41*2), sqrt(7056), (unpack(c,H)-2), oct(115), 10);'
    8. Re:*sigh* by omarius · · Score: 2
      If you lived in a population where aids is of epidemic proportions but it costs so much to get vaccinated what would you do? Die so another company can profit?

      For one thing, assuming I get to keep my personality and personal habits in your hypothetical transplantation, I would be in no more danger of getting AIDS in Brazil than I am here in Virginia.

      For another thing, there is no HIV vaccine. And I think the person who invents it deserves to be richer that Bill Gates.

      Sure the government should have licensed the medication, but on the other hand, the profiteering and money grubbing developers should have provided for brazil long before they needed to make this stance.

      Your first point is correct. Rather, the Brazillian Government is the only party responsible for the Brazillian people. Your second point misses mine completely. Just because I need something does not mean that I am entitled to it. I cannot steal bread because I am hungry -- I cannot steal medicine because I am sick. Is this because I am not Brazillian? Or that my hunger and sickness are not as important as Brazillian hunger and sickness?

      Its ironic how we think IP in technology is different then IP in medicine. Why is it right for people to patent vacinations that could save your life, but it isn't right for someone to patent an interface that has no position of life or death?

      I think you are inferring that I feel the same way about software patents. I don't really have a clear opinion on that, for other reasons, that are off topic and not worth discussing here. We've heard them all before anyway.

      -Omar

    9. Re:*sigh* by Matthias+Wiesmann · · Score: 2

      Funny, we all talk about free as in speech, free as in beer, but never about the freedom to survive. This is not a freedom that is given, this is typically the freedom you take, and surprise - if you don't take it, you die.

      The issue here is not whenether this is just or not, or even legal (which in this case is debatable). The issue is about dying or not. If you where in the same situation, you would take the same decision. Of course, you need to prentend that something justifies what happens to them, they did this or that wrong... Surprise, shit happens, and if you don't have enought money, you're fucked. So you either sit there and die, or do something...

      The day you get cancer or another serious illness, and will not be able to pay the medication you will also don't care about the pharma's funding IP law, you will want to live.

      The only thing you can be sure is that other people will find good excuses why you should die, you should have worn more sun-screen, you should not have eaten marshmallows, you should not have lived in the US, you should not have worked with a computer, of course with such a livestyle you had it comming, etc...

      I just hope you won't need to understand this the hard way...

    10. Re:*sigh* by radja · · Score: 2

      Even if they did (I don't know), there is a clause which allows governments to suspend patents, exactly for cases like this. And industry got a say in those patent agreements too, so they shouldn't whine when it is used in a correct manner.

      //rdj

      --

      No one can understand the truth until he drinks of coffee's frothy goodness.
      --Sheikh Abd-Al-Kadir, 1587
    11. Re:*sigh* by omarius · · Score: 2
      Since your unlikely to read anything that is critical of your views[. . .]

      Why do you think that?

      And I've read it before. You might notice that the first sentence under the first heading of that document reads: The status of intellectual property rights (copyrights, patents, and the like) is an issue that has long divided libertarians.

      -Omar

    12. Re:*sigh* by Sir_Real · · Score: 2

      mod parent up please

    13. Re:*sigh* by omarius · · Score: 2
      Funny, we all talk about free as in speech, free as in beer, but never about the freedom to survive. This is not a freedom that is given, this is typically the freedom you take, and surprise - if you don't take it, you die.

      I think that you are inferring that survival is a "right" as opposed to a "freedom" -- or at least in the way I use those terms. If I am correct in my assumption of your meaning, then I must disagree. Survival is not a right. You have no right to live -- only the right to be free from being harmed by others. If I push you in the water, then I am an attempted murderer and deserve to be harshly punished. If I see you're in the water and I deign not to risk my life to save you, I may be unkind, but I am not infringing your rights, either. Likewise, you have no right to have your brother or your government point a gun at me and force me to risk my life to save you.

      The day you get cancer or another serious illness, and will not be able to pay the medication you will also don't care about the pharma's funding IP law, you will want to live.

      I sure will! But again, I have no right to expect someone to help me. As I stated in another post, I do not have a right to something just because I need it. I need money to get my pickup truck fixed. Will you give it to me? I need my truck! I demand your money! I have a right to your money -- you don't need it as much as I do! Do you see how foolish that is?

      And yes, your last point is correct. I think everyone is responsible for their own actions. If I do something that kills me, then it is nobody's fault but my own, now is it? If it is my lifestyle to jump out of the tops of trees, are you going to pay my medical bills for me? Because I am hurt and have a right to your money?

      -Omar

    14. Re:*sigh* by SubtleNuance · · Score: 2

      This should make sick every one of you that has a Free* bone in their body.

      Most everyone else on the planet dosnt believe that they are "free" to abuse government greed (gov-granted monopolies) to kill people, in effort to make themselves massive profit.
      Drugs are inventions, as much as gadgets are inventions, and this is IP theft, plain and simple.

      IP dosnt exist. Intellectually free societies cannot have 'intellectual property' lest they be complacent hypocrites. Patent law was a condition, an agreement, where people would forsake their rights to do as they wanted in effort to reward creation. This is obviously, especially in this case NOT a 'fair deal'. People are dying -> your profit 'right' ceases. Simple.

      If I spent a fortune researching and creating a drug, you bet I would be pissed if someone else started making my drug without my permission.

      You dont know anything about BigPharm. They spend far more on Marketing (pen-giveaways/junkets/propaganda) than research. Even their research is Seriously subsidized by public grants && further aided by massive tax breaks for what they do spend. See: http://www.mercola.com/2000/june/24/pharmaceutical _industry.htm

      Does Libertarian now mean "misguided, myopic, clueless freemarket fetishist"? I always knew libertarianism was an extreme free-market religion where people wage economic wars, and 'economic' might was right where capital owners could do as they pleased. Have Libertarians devolved into street-thug-styled-anarchists* without a conscience?

      *Apologies to cluefull Anarchists, Anarchist in the Traditional-Political sense, not the clueless USA synonym for 'street-thug who advocates chaos.'

    15. Re:*sigh* by Hadean · · Score: 2

      >since the rest of the world would boo us off the
      >planet.

      With good cause... Money Vs. Life. That eternal question that's so easy for us as individuals to answer, but impossible for a society to answer. You say money (and would prefer a new born child to die a horrible death), I say life (and would not want to see a rich white man get millions upon millions atop his already rich fortunes).

      >This world is going to shit.

      I agree, but for different reasons.

    16. Re:*sigh* by Hadean · · Score: 2

      Oh, and by the way...

      >or whatever it is that Brazillians do to get AIDS

      Try learning a fucking thing or two before condemning people to die.

    17. Re:*sigh* by Joao · · Score: 1

      Omar wrote:
      >
      > But instead of educating and changing killer lifestyle habits, their government steals IP.

      You're misinformed here.

      Brazil has had one of the most successful AIDS awareness, education, and prevention campaigns in the world for several years now. EVERY country in the world has AIDS nowadays, and Brazil is in the forefront of both prevention and treatment of this disease.

      Yes, this case deals with IP infringement. But it is necessary IP infringement. The pharmaceutical companies with their almighty greed shot themselves on the foot on this one by charging such outrageous markups on the drugs they produce. And they know they can charge this markup since the people who need these drugs do not have a choice but to pay. You either pay or die, simple as that. But the problem is that people in poor countries cannot possibly afford the $15,000 dollars per year that the pharmaceutical companies charge for these drugs. For the vast majority of people in the world, AIDS is a death sentence. And trust me, these drugs do save lives. I have friends with AIDS who have been living very good and productive lives for over 15 years now thanks to these drugs.

      The Brazilian government is producing the same drugs for a cost of about $700 per person per year. These are exactly the same drugs, manufactured exactly the same way. So the additional $14,300 dollars the pharmaceutical companies charge for these drugs are profit. That is the price they put on a human life. The way they look at it, if you're not willing to pay the 2100% markup, you die.

      700 dollars per year is still far too much for most people. But that works in combination with an aggressive AIDS awareness campaign in Brazil that greatly reduced the spread of the disease, so instead of the predicted 1.2 million people infected, actual number of cases is about 500 thousand. So the total cost of treatment went from $18 billion dollars (15k x 1200k) to $350 million (700 x 500k). 350 million is a figure that the government can afford to pay, so the entire treatment is free for the patients!

      I am Brazilian, and I have always been a very strong critic of the Brazilian government. Yet every time I read about what they have done in this case makes me want to brake into spontaneous applause.

      Cheers.

    18. Re:*sigh* by PSC · · Score: 1

      Apparently everyone here believes that companies' R&D is the only way to invent drugs, thus assuming that there would be no more drugs once companies don't get their return on invest.

      Can you say "University", anyone? There is still very active public research in many countries. We aren't doomed just because a company stops making a certain drug.

      But instead of educating and changing killer lifestyle habits, their government steals IP.

      Where exactly does it say that the Brasilian govt. does not educate their people? This is not about either/or, but about doing both, educating those for whom are not infected, and caring for those who are already infected.

      Life isn't that simple and one-dimensional.

      should make sick every one of you that has a Free* bone in their body [...] *as in Libertarian free, not social-welfare-state free.

      Frankly, my Libertarian bones hurt the most.

      --
      --- The light at the end of the tunnel is probably a burning truck.
    19. Re:*sigh* by squarooticus · · Score: 1

      > Patent law was a condition, an agreement, where people would
      > forsake their rights to do as they wanted in effort to reward creation. This is obviously,
      > especially in this case NOT a 'fair deal'. People are dying -> your profit 'right' ceases.
      > Simple.

      So, now that pharmecutical companies know there is no profit in making life-saving drugs, far fewer such drugs will be developed. Thus, you will have a far greater likelihood of dying from something that could have been cured. Simple.

      You can't repeal the law of supply and demand. If there's no profit potential in something, the free market will not produce it, and it will have to emerge (much more slowly) from charity.

      The bottom line is that anyone who understands how the free market works and who values life will support intellectual property and limited monopolies on life-saving inventions. In destroying IP for just those things that people need because "making profit off the suffering of others' is wrong," they're just prolonging the suffering.

      I know I would rather take the chance of not being able to afford the cure for a particular disease for 20 years after the cure was found (the monopoly period) than cause the cure never to be found by supporting illogical social policies that villify the free market at the expense of progress.

      To all of you who think you're taking the moral high-ground by opposing profit from life-saving inventions: "I was right" will make a great epitaph.

      --
      [ home ]
    20. Re:*sigh* by Absynthe · · Score: 1

      oh god, libertarians for a one world government, i never thought i'd see this day.

      ok, when did freedom become the right to slate patent laws over the entire world? This wouldn't have even been an issue if the company wasn't able to sue via the WTO, specifically under the TRIPS agreement. Earlier attempts were made at the inception of the Uruguay Round, about 50 countries did not confer protection for pharmaceutical products. The TRIPS Agreement obliged all WTO Member countries to recognize such protection. There is some wiggle room under TRIPS however. The TRIPS Agreement is not a uniform law (Unctad, 1996). It only sets forth minimum standards to be provided for. Any WTO Member may grant a broader protection than that required under the Agreement, but it can not be obliged to do so (article 1). Article 7 of the Agreement ("Objectives"), establishes a general framework for the interpretation of its provisions. It aims at balancing the interests of innovators and users of technology in the protection of intellectual property, in a manner that enhances "social and economic welfare".
      I'm sure Roche exec's aren't standing in line at the soup kitchen. It's not like Brazil robbed a shipment of drugs and passed them out. I think it's pretty telling when they can save the kind of money they can by making the drugs themselves.
      I'm just disapointed in your whole line of reasoning, you are supposed to be for less legislation and you are backing a non-democratic treaty based form of law from which you were restricted from participating in.

    21. Re:*sigh* by Rupert · · Score: 2

      Likewise, you have no right to have your brother or your government point a gun at me and force me to risk my life to save you.

      Burned your draft card, did you?

      --

      --
      E_NOSIG
    22. Re:*sigh* by omarius · · Score: 2
      I would, but I'm too old now. :)

      Don't let's get into any discussions about the Constitutionality of the non-volunteer army, ok? I won't if you won't.

      -Omar

    23. Re:*sigh* by Matthias+Wiesmann · · Score: 1
      I think that you are inferring that survival is a "right" as opposed to a "freedom" -- or at least in the way I use those terms. If I am correct in my assumption of your meaning, then I must disagree. Survival is not a right. You have no right to live -- only the right to be free from being harmed by others. If I push you in the water, then I am an attempted murderer and deserve to be harshly punished. If I see you're in the water and I deign not to risk my life to save you, I may be unkind, but I am not infringing your rights, either. Likewise, you have no right to have your brother or your government point a gun at me and force me to risk my life to save you.

      This is intersting, and shows a different mind-set. In certain european coutries, not helping people who are at risk is considered a crime, in french is called "Non assistance à personne en danger". In the US you can get sued if you help somebody in a accident, in europe, you migth get sued if you dont' help the person (of course, if saving the person represented a risk for you, you will not be sued.

      Anyway if we take the truck analogy further. I don't have the money - my survival depends on the truck. Why would you have the right to money - where do you find this? In the human right declaration? There is no such thing as a right for money - corporation would like this right to exist, but it simply does not. You can invent it, maybe your country defines such laws and rights, but mine do not. In the end it's simply your beliefs (or your countrie's) against mine.

      Anyway, if I really risk my live, and will do whatever it takes to survive. This means stealing your truck, hurting you in the process. If you think about decisions, I am in a win-loose situation, you are in a loose/loose situation. The most reasonable solution is for you to lend me your truck (minise loses). In the case of pharma corporations, this means loosing money they would never have gotten - in fact they could have sold the cheap derivative themselves, and win some money.

      I sure will! But again, I have no right to expect someone to help me. As I stated in another post, I do not have a right to something just because I need it. I need money to get my pickup truck fixed. Will you give it to me? I need my truck! I demand your money! I have a right to your money -- you don't need it as much as I do! Do you see how foolish that is?
      So if we follow you logic, the jews had no right to ask to live. So refusing them access to a country (as switzerland did) on basis on money was right? If this is the case, this would end a lot of debate around here...

      The problem is that you make no distinction between normal, civilised situations, and emergencies. Laws, justice, capitalism, all those nice words and principles only exist in a civilised context, in case of emercency, it all falls down.

      Also you base all your reasoning on the idea that there is a large difference between doing things actively (me killing you) and passively (me doing nothing to prevent you from dying). This difference can be quite subtle. If I kill you by not stoping my car active? If I kill you by swerving a little bit? At the extreme, intent can often be blended with negligence or stupidity. Off course, stupidity cannot be a crime...

      And yes, your last point is correct. I think everyone is responsible for their own actions. If I do something that kills me, then it is nobody's fault but my own, now is it? If it is my lifestyle to jump out of the tops of trees, are you going to pay my medical bills for me? Because I am hurt and have a right to your money?
      The problem is not a fault problem, the problem is about access to proper care. In this case we have the choice of giving people access to the proper care, or pushing them to act against us. From a cilvized logic (we want to get along reasonably well) you get into a war logic (your survival implies fighting me). In this logic, not only the rules and your money are threatened, but also your survival.
    24. Re:*sigh* by omarius · · Score: 2
      So if we follow you logic, the jews had no right to ask to live. So refusing them access to a country (as switzerland did) on basis on money was right? If this is the case, this would end a lot of debate around here...

      1) This makes no sense. Or perhaps, I cannot follow your leaps of logic. In either case, I think i have said enough on this subject in other posts. Which is good because:

      2) I believe this is enough for me to invoke Godwin's Law. This thread is now over.

      -Omar

    25. Re:*sigh* by vidarh · · Score: 2
      First of all, as others have noted, this is compulsory licensing, which is legal in Brazil. Second, it can't be theft, because patents are not legally property, but a government granted protection, in the same way that a copyrighted work isn't property, allthough it is still to some extent protected.

      The distinction is important. Patents and copyrights are time limited grants of monopoly or licensing rights done by a government to give an incentive for innovation for the public good. If the government decide that a certain license isn't for the public good, there is a very strong argument for revoking that license - and in Brasil the government indeed have a law to back up that right.

      This is the essentially the same concept that is behind copyright and patents, and even corporate charters in the US. Actually, many states in the US still have chartering laws on the books (some even in their constitutions) granting the legislature the right to detail control the charter granted to any business, and to revoke it if the corporation acts against the public good.

      Too bad none of them use those rights these days.

    26. Re:*sigh* by Anonymous Coward · · Score: 0

      I'm a 24 year old virgin...

      shock gasp horror... yes it is possible to have a livable life without fucking the crackwhores you obviously do nightly...

    27. Re:*sigh* by garcia · · Score: 2

      I don't agree. There is absolutely no reason that someone should be denied access to a drug just b/c some company wants to make profit.

      AIDS is a real threat to EVERY single fucking person in the world. I don't think that the treatment should be limited to those that can afford expensive health care, have unending funds, etc.

      Some of these people contracted the disease w/o doing something (fucking, sharing needles as was mentioned above) they were born w/it, were pin pricked at work, whatever. Are we really going to not allow these people a chance b/c some company wants money?

      I don't care what anyone else says. Drugs that can save lives need to be seriously reduced in cost (why the fuck does a prescription cost $100+ for a few pills)? I think that these companies are worse than drug dealers trying to rip you off.

      Give us a break. IP my ass. They are stealing lives, I feel that lives > IP.

    28. Re:*sigh* by CodeMonkey555 · · Score: 1
      Actually, part of freedom is having to live with the choices we make. By eliminating the ability of the government to use coercive power over us, we must be willing to make important decisions for ourselves and live with their consequences. I am not taking an anti-gay, -drugs, or -AIDS stance here. I am simply disputing your assertion on the nature of freedom.

      For a good read, try "The Constitution of Liberty" by Friderich Hayek.

    29. Re:*sigh* by MeNeXT · · Score: 1
      I am torn here!!! While I understand the Brazilian government I can't stop to wonder if this trend continues what's going to happen?!?


      Imagine that all contries decide not to respect IP on drug patents for whatever reason including saving lives. Then 2 to 10 years down the line a new Virus or epidemic, call it XYZ, comes along.


      Now everyone remembers what happened to the AIDS IP and noone wishes to risk money in developing a cure in case the governments decide to confiscate this IP as well. So people start dying and nobody invests. People continue to die untill when????


      The issue is we need to safeguard the research for a given period of time in order to have a return on investment after that anyone can produce a generic product.

      --
      DRM? No thanks, I'll just get it somewhere else...
    30. Re:*sigh* by Anonymous Coward · · Score: 0
      I cannot steal bread because I am hungry

      Oh, but you will steal it if you haven't eaten for a week. You see, your high morals only apply when you're sitting at your home posting to slashdot not really hungry yourself. Once you know what it is like to starve, you will steal. You do it to survive. Any human would.

    31. Re:*sigh* by iomud · · Score: 2

      Ah but I said nothing about the nature of freedom I did however say "People make mistakes it's the nature of being human." The nature of freedom is being allowed to make mistakes, it is not being punished un-necessarily for them. Letting either you A.let infected people die or B. Give them medication and let them live. It's a no brainer. It's very rare that a punishment should be death for a mistake. Not to mention children born into it as I did earlier. I whole heartedly agree with you about the nature of freedom, however often times when it's a life and death decision caution is thrown to the wind and rules go out the window as in this case.

    32. Re:*sigh* by dominator · · Score: 1

      Unfortunately, this is not about helping people when it's not in your best interest. It's closer to you being forced to help someone when it's not in your best interest...

      Brazil is trying to play "Robin Hood" here, and it's just not right.

    33. Re:*sigh* by Harmast · · Score: 2
      I hope you're reminded of this when someone dosen't help you when it isn't in their best interest.


      And I hope you remember this attitude when you or yours gets whatever the next big plague is. Governments make lots of demands, expensive demands, on drug companies that knock off a lot of promising drugs before they get to market (not just because of side effects...if you are working on drug X and your competitor gets drug Y approved that is just as effective as drug X against the target disease before you get X approved all R&D on X is now gone...the FDA will only approve drugs that are more effective in some way (fewer side effects, fewer non-response, treat worse cases, etc) than existing drugs and make even the ones that are released a very long term and expensive proposition.


      Those tests and hoops are not jumped through by faceless corporations, but by people just like you...people who spent a lot of time in school working to understand the underlying science or getting medical training or mastering statistics and who, like you, want to be paid. Even a non-profit drug company would face huge costs and the legal need for companies to make a profit (fiducary responsibility) only increase them. Thus, if the producers of AIDS drugs have to face confescation of those drugs by countries without compensation when the plague after AIDS shows up how many drug companies will spend the money.


      Right now there are tons of 'safe' profits in drugs for male impotency, better contriceptives, hair loss, weight loss, allergies, and so on. All of these will sell well in rich countries where the government will not infringe on patents thus risking the R&D costs never being repaid on both successful and unsuccessful drugs. Facing a choice between those and working on the next AIDS knowing poorer countries will just up and take your results with no compensation.


      As it is, these AIDS drugs really exist because of AIDS being a big disease in the first world. Until the past few years malaria was the biggest killer in Africa and had been for a centuary or more, but there is little advance in malaria drugs. Why? Because the first world ended it with DDT before deciding DDT was too dangerous to use (before massive usage of DDT to wipe out malaria carrying mosquitos malaria was a common problem in even the US, including Washington DC). With this Pfizer, Roche, Brystol-Myers-Squib and the others must be asking "will this happen with a malaria vaccine, too". And they will ask the next time a drug is ravaging the third world.


      And if you or yours gets that disease how will your attitude on AIDS have helped you?


      There are other methods to solve this: charity, loans, limited licsencing, and many more. Just blowing the patent is not. Yet the former could have set a positive framework for the next plague. Now we have set a negative one.

      --
      Herb
      Again, feel free to sentence me to death if my questions annoy you. I'll come back in 5 minutes anyway. -Sythi
    34. Re:*sigh* by mimbleton · · Score: 1

      "to heal the ill in society and turned to being a profitable business "

      It did when somebody noticed that people will work much harder and have better results when given opportunity to get rich.

    35. Re:*sigh* by Anonymous Coward · · Score: 0

      1.) It is hard to say that Brasil is stealing from pharmaceutical companies when the only reason that Brasil does not buy their drugs is that they would not give Brasil the drugs at a reasonable cost. So now Brasil instead of not supplying drug to their people can give them the drugs. Either way the companies would not get the money because Brasil either makes their own or does not buy the drugs. Brasil still buys a few of the drugs form these companies Brasil just does not buy the majority because they can not afford it.

      2.) Brasil also is not selling these drugs to other countries the drugs are just for their people. Brasil has one of the best aids programs in the world, every person in Brasil that has HIV gets treatment which is only posible because they manufacture their own drugs. The USA does not even do that.

      3.) Brasil making their own drugs for aids is not new, just this lattest drug. Brasil has been making most of these drugs for many years, they researched how to make them and manufactured all with in their country.

      4.) "Hell, in the long run, education will save a lot more people than this drug. This drug will not make Brazillians stop fucking each other or sharing needles or whatever it is that Brazillians do to get AIDS."
      A lot of people post here seem to think that Brasil has some kind of epidemic and no education about HIV, this is soooooo wrong. Brasil happens to have a lower % of HIV than the USA and Brasillians are better educated about HIV than Americans and aids victims in Brasil live much longer and better than most anywhere else in the world.

      Sorry if this seems incoherrent but my spelling and grammer suck. ;-)

      Charles Clarke
      charles@ink4art.com

    36. Re:*sigh* by mimbleton · · Score: 1

      "not helping people who are at risk is considered a crime"

      So is in US.
      Get your facts streight before posting this sort of crap.

    37. Re:*sigh* by mimbleton · · Score: 1

      "to see a rich white man get millions upon millions"
      If it weren't for that rich white man we wouldn't have anything to discuss here, would we ?

    38. Re:*sigh* by mimbleton · · Score: 1

      He is not condemning anyone, you stupid fuck.
      Most of the victims are so thanks to their own careless behavior.

    39. Re:*sigh* by iomud · · Score: 2

      I see this as man helping man, some see it as an way to make money and assert control in third world markets. What are patent's about? Control and ownership. Yes the patent was "blown". I have no logical answer, I'm not calling the people who are "blowing" it saints, people are dieing we have something that can help them, we should use it. End of story. Dead people don't make house payment's, they don't mow their lawns and they don't buy foreign goods. They do however get burried in patent's and politics apparently.

    40. Re:*sigh* by jafac · · Score: 2

      not to mention the hundreds of thousands poor Chinese who have HIV because they made the poor moral choice of donating blood.

      (Chinese blood donation agencies would take the blood, mix it ALL into a big vat, remove the plasma, and send the rest back to be reinjected into the donors so they don't get anemic)

      Yes, a poor government policy caused the epidemic there, and you can bet China will soon be following Brazil's lead, they're already communist, afterall.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    41. Re:*sigh* by Frederic54 · · Score: 2

      so you should agree that patent the human genome is a Bad Thing(tm)? How can people, especially R&D of pharma companies, try to patent a thing like this? which is not a gadget nor invention nor IP, it's like patent on software or mathematics or "technology to put a hyper link in a text so when you click on it you go on another page" or the 1-click patent, shame... You have to fight the patent office, nothing else.

      --
      "Science will win because it works." - Stephen Hawking
    42. Re:*sigh* by omarius · · Score: 2
      No, I don't think that the Human Genome should be patentable -- it's a priori. It already exists. Patenting it is like patenting the contents of the Rosetta Stone.

      On a side note -- if anyone is reading comments this far downstream -- since posting my comment, I have been accused (in addition to your comment), of hating the Jews, of being gratified by the deaths of Brazillians, of actually muduring Brazillians, of being "Right Wing Shit," of being closed-minded, and several other things that have NOTHING TO DO WITH MY POINT.

      The moderation of my comment has been flopping around like a steak in a pool of pirhana.

      A lot of people who have responded are, IMHO, the most dangerous sort of people -- short on wit, and full of hate.

      I'm not necessarily accusing you, Frédéric, I'm just complaining. It's a shame, because I enjoy a good argument.

      -Omar

    43. Re:*sigh* by jafac · · Score: 2

      Similar situation in Macedonia right now.

      There were a huge influx of Armenian refugees into Macedonia from Serbia during Milosivec's reign of terror. Macedonians didn't want them, because they didn't want a population-induced power shift to destabilize their own country. Nothing personal.

      But it happened. The refugees came, and Macedonia was pretty much forced to take them. Now we're sending peacekeeping forces.

      Would it have been right to turn these people back at the borders, tell them to go back to their homes and wait for the Serbian death squads to come by and gang-rape them and execute them, not necessarily in that order?

      Also, since the Swiss were not Nazi - Godwin's law does not apply.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
    44. Re:*sigh* by Anonymous Coward · · Score: 0

      Yeah, we'd all probably be too happy playing in our backyards without a care in the world...

    45. Re:*sigh* by Hadean · · Score: 2

      The way it was worded made it sound like the parent of my reply didn't even know how Brazillians received the HIV virus in the first place "or whatever they do" ... If he doesn't understand how AIDS can be transmitted, UNKNOWINGLY, through normal means, blood transfusions, sex with a partner claiming he/she is safe, etc. then he shouldn't be commenting. Many of the people drugs like these would cure are INNOCENT people who didn't just wake up one day and decide, "Hey, I'm going to have sex with a dozen people to see if I can get AIDS!" ... But hey, what am I talking about? AIDS is obviously something people do to themselves right? They all deserve to die, isn't that what your saying? Nice attitude... *sigh*

    46. Re:*sigh* by mimbleton · · Score: 1

      Funny you mention that ...
      That is exactly what they were doing whenever and wherever White man found them.

    47. Re:*sigh* by mimbleton · · Score: 1

      "If he doesn't understand how AIDS can be transmitted, UNKNOWINGLY, through normal means, blood transfusions, sex with a partner claiming he/she is safe, etc. then he shouldn't be commenting. "

      You know damn well that great majority of people who got AIDS did not get it in "innocent" ways listed by you.
      Please stop pretending that AIDS can strike anyone at anytime and there is nothing we can do about it.

    48. Re:*sigh* by Hadean · · Score: 2

      A Brazillian Slashdot user posted a message somewhere concerning 8 children who had AIDS... How are they not innocent?

    49. Re:*sigh* by mimbleton · · Score: 1

      They are. Most likely it was their parents who engaged in unsafe behaviour.
      The point is that AIDS is not "God's will" type of disease.

    50. Re:*sigh* by aprentic · · Score: 1

      >This drug will not make Brazillians stop fucking >each other or sharing needles or whatever it is >that Brazillians do to get AIDS.
      You fucking racist. And I'm half Austrian. Brazil can't afford the education programs that we have.
      Up untill a few decades we couldn't either. The United States used to steal every patent under the sun.

  22. Looks like Brazil figured out what nobody else can by Uttles · · Score: 1

    To hell with the drug companies. That's what Brazil said. You know why? They have figured out the drug companies' scheme. Whoever it is that makes these drugs, they're just like all the other companies that make drugs for all the other diseases: rather than make drugs that could cure or prevent HIV, they just make a drug that will let you live with the ailment. Think about it: how many times would you take a vaccine or a cure? Once? For a period of a few weeks? Now think about how many times you take medicine that lets you live another month... you take it all the time, for the rest of your life! So basically they're acting just like a bunch of drug dealers. How does a drug dealer make money? On the come-back.

    So Brazil realized that like a bunch of heartless gangsters the drug companies' are selling these high priced HIV pills to dying people so that they can live to pay another drug bill. However in this case, it was Brazil that was footing the bill, so they said to hell with it, we're making our own damn drugs. Well, way to go Brazil! I hope other countries wake up and take similar action.

    --

    ~ now you know
  23. Solidarity for Brazilians by SubtleNuance · · Score: 1

    Congratulations Brazil. Your government, and people should be given a great thanks from the rest of us - YOU have finally started standing up to these capitalist whores.

    Come to Washington, D.C., Sept. 28th, to Demand that the Governments of the rest of the planet start ruling on behalf of their citizens as well.

    Bravo Brazil!

  24. No More AIDS Drugs, I Guess by splattertrousers · · Score: 1
    Now that nobody is paying for AIDS drugs (Brazil isn't the first country to ignore the patents), what incentive do drug companies have to spend the money to develop new ones?

    And before you say "to help sick people", let me ask this: how many people do you think would donate money to pharmaceutical companies for research? Many people think they are just greedy evil companies out to steal money from poor sick people.

    1. Re:No More AIDS Drugs, I Guess by CSC · · Score: 1
      Now that nobody is paying for AIDS drugs (Brazil isn't the first country to ignore the patents), what incentive do drug companies have to spend the money to develop new ones?

      And before you say "to help sick people", let me ask this: how many people do you think would donate money to pharmaceutical companies for research? Many people think they are just greedy evil companies out to steal money from poor sick people.

      Here's the scoop for you: I pay taxes to fund public research. I'll never give a cent to pharmaceutical companies .
      --
      -- Colin
    2. Re:No More AIDS Drugs, I Guess by praedor · · Score: 1

      The hell you wont and the hell you don't. Are you saying you NEVER pay for drugs? You NEVER get sick and receive a prescription from your doctor?


      Public monies pay for BASIC research, not specific, targeted, medical research. Even when it does, it only does proof of concept, and it is usually aided by drug company funding.


      Pharmaceuticals need for public funding to handle basic research. They have the job of using the results of basic research to develop specific drugs - and it costs shitloads to do it. Damn straight they deserve to get a return on their huge investment. I say that you must now forgoe EVER buying any other drug if you don't want to pay drug companies. You must forgoe EVER going into a hospital for surgery because you would end up receiving drugs and anesthetics produced by pharmaceutical companies (none by public-funded university research except indirectly via basic research).


      Public money would never have produced the drugs we now have to treat AIDS or any other life-saving drug.

      --
      In Bushworld, they struggle to keep church and state separate in Iraq as they increasingly merge the two in America.
    3. Re:No More AIDS Drugs, I Guess by why-is-it · · Score: 2

      how many people do you think would donate money to pharmaceutical companies for research?

      By extension, how many people would donate money to micro$oft for software research?

      --
      *** Where are we going? And what's with this handbasket?
    4. Re:No More AIDS Drugs, I Guess by Anonymous Coward · · Score: 0

      Of course all those saying that this action means that drug companies will stop producing drugs are clearly right. After all, nobody ever produces anything that isn't covered by a patent, do they?

    5. Re:No More AIDS Drugs, I Guess by mimbleton · · Score: 1

      "I pay taxes to fund public research"

      So did Russians where there were no private pharmaceutical companies.
      Where is that "advanced" Russian 100% public-founded pharmaceutical industry now ?

      Or do you believe that Russians are inferior and you and your country would do much better ?

    6. Re:No More AIDS Drugs, I Guess by Anonymous Coward · · Score: 0
      They have the job of using the results of basic research to develop specific drugs - and it costs shitloads to do it

      IN WHAT WAY? Can someone who says this please bother to back it up with just a single link? I guess you think we all just know how much money it costs to do drug research. That's what the drug companies who make an 18% return on their business dealings tell us. Where are the figures?

  25. Drugs for Profit by cd-w · · Score: 3, Insightful

    While I hate to side with the large drug companies on such a sensitive issue:

    It is a fact of life that if the drug companies do not get paid for their R&D, then they will not bother to produce new drugs for combating AIDS and similar diseases.

    As proof of this, consider how many new Malaria drugs are produced? Basically, there is no profit in R&D for malaria, so drug companies simply don't bother.

    So, in the short-term this may seem like a good idea, but in the long term it could do serious damage to the search for an AIDS cure.

    1. Re:Drugs for Profit by TrollMan+5000 · · Score: 1

      Perhaps patent protection is too lengthy in this case. While I agree with you, companies need to get paid for R&D, perhaps current law (17 years?) is too long a term. AIDS has been a problem for quite a while now, and better effort is needed to stem the spread of the disease.

      We still need patent protection, just shorter terms.

    2. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      "then they will not bother to produce new drugs "

      Rather, they CANT produce new drugs.

      Noone can spend billions of dollars on something that are then given away for free.

    3. Re:Drugs for Profit by registered_AC · · Score: 1

      The problem is just that, the drugs are produced for profit.
      If you put the enormous profit these big drug companies make into making the drugs cheaper, Brazil wouldn't have to do this.
      I don't understand how you can prioritze your profit over other peoples lives.

      But the root of the problem is that this kind of research is conducted by companies at all. If you fund research without trying to maximize profit, more drugs will be developed for e.g. malaria and other poor-mans-diseases and the drugs could be made cheaper!

    4. Re:Drugs for Profit by Hadean · · Score: 2

      Humans are a strange bunch sometimes... Tens of thousands of people are dying in a poor country that couldn't afford to pay these companies for their research and pills, yet we attack them for ripping off these multi-billion dollar companies, many of whom have been caught doing undasterdly things themselves (sending expired medicines to Africa and other poor countries and using that "aid" and "goodwill" as advertising, overcharging countries who can't afford medicine, etc.).

      I guess, in a way, you can boil it down to, What's more important: Making money or saving lives/helping your fellow human? If this were a perfect world (which it obviously is not), universities or other not-for-profit organizations would gladly take up the research and not expect to earn a profit (at least, earn enough to cover R&D, which most pharmaceutical companies make 10-fold).

    5. Re:Drugs for Profit by Edd · · Score: 1

      So you are saying that drug companies will only make drugs if there is a profit motive there. This means that when the AIDS problem dies down in the rich countries (with good education and available precautions that could happen in 10 years) the drug companies will give up on the search for a cure, leaving the poorer countries swinging in the wind.

      Malaria drugs are no longer developed because Malaria is only a problem in poor countries, this will happen to AIDS as well. The drug companies do not care about the people on the streets of Brazil so why should Brazil care about Roche?

    6. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      If the pharmaceutical industry is going to argue that this will prevent them recouping R&D expenditure, they should provide figures to back up their argument.

      The agreement with the WTO that covers these patent laws specifically allows for "compulsory licensing" under exceptional circumstances.

      In fact, compulsory licensing happens quite frequently in the States, as I understand it.

      If Big Pharma could make a good case for this being a bad decision, I expect that they would.

      I suggest you stop making excuses for them.

    7. Re:Drugs for Profit by dipsy33 · · Score: 1

      >As proof of this, consider how many new Malaria >drugs are produced? Basically, there is no >profit in R&D for malaria, so drug companies >simply don't bother. AIDS is similar in this respect: research on AIDS has been stalled for several years. AIDS epidemics take place mostly in 3rd world countries. The cases in "civilized" countries are negligible (to the pharma-industries). Since 3rd world countries are already paying merely a fraction of 1st world countries pharma-industries have been focusing on drugs which they can sell in 1st world countries (and make a good profit from), such as blood pressure medication or cholesterol medicine. This will only speed up the process. I bet in 30 years we will still be using ATZ and other antiquated drugs for treating AIDS...

    8. Re:Drugs for Profit by rossjudson · · Score: 1

      I guess the real question is, why is R&D so important? I heard a few months ago on NPR that the drug companies play extensive games with their accounting to make it LOOK incredibly expensive to do drug R&D. When you think about it, it's absolutely in the best interests of the drug companies to do this. The figures being tossed around were (for some drug I can't remember) a drug company figure of $800 million for R&D, and a contrary figure of $125 million by a watchdog group's accounting.

      Other things that add to the cost include the vast cost of litigation in this country, and incredibly destabilizing effects of outlandish juried settlements.

    9. Re:Drugs for Profit by edremy · · Score: 2

      Perhaps patent protection is too lengthy in this case.

      Not even close: it's vastly too short. Drug companies recently got an extension on the length of patents for drugs.

      Why? Because it takes 10+ years from patent to first sold dose. Drug R&D is very, very slow- you can't just make the compound and sell it. Animal tests run years. Then the healthy human tests, then the sick human ones. Better wait 3-5 years after each to check for long-term side effects, although you can at least run them staggered. Even that won't find a lot of the problems, as Bayer recently found out with Baycol.

      AIDS treatment advocates have been pushing the FDA to speed up this process, with some results. (And justification- after all, if you're going to die anyway, who cares if there are bad side effects?) But for a "normal" drug like a statin, well over half the patent period is wasted- drug patents used to be for effectively ~7 years, although the extension (24 years IIRC) has pushed it into the double digits.

      Eric

      --
      "Seven Deadly Sins? I thought it was a to-do list!"
    10. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      "I don't understand how you can prioritze your profit over other peoples lives. "

      It isn't at all about "prioritze your profit over other peoples lives".

      It's quite simple, if the companies can't make money on it. We will not see any more drugs.

      It all about making a company climate that makes it possible to invest billions of dollars on research a decease. Without patents this possibility doesn't exists.

    11. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      "I heard a few months ago on NPR that the drug companies play extensive games with their accounting to make it LOOK incredibly expensive to do drug R&D. "

      I know for a fact that this statement is bullshit.

    12. Re:Drugs for Profit by GregWebb · · Score: 5, Insightful

      This is a serious post, not a troll, not flamebait but I'm still fishing out the asbestos modem.

      Uncomfortable a truth as this is, it only highlights the fundamental problem of capitalist research. When (a category of) research into improving the human situation is only carried out by capitalist organisations, that research is inevitably going to be targetted around the needs of those most able to pay for the end result. Who, let's be honest, aren't going to be the greatest possible recipients of research to improve the human situation.

      Now, AIDS research is very important. Partly due to the massive third world AIDS pandemic (except, oops, they can't afford the drugs...) and partly due to generic research intro retrovirii. But think about what could happen if the money put into various other bits of research was spent on, for examples, cholera, river blindness, malaria, measles and so on. I'm not going to provide examples of possible targets for the money to come from, that's just going to get emotive.

      Think about it, though. If medical research was primarily (or entirely) funded by society as a whole as opposed to by the proceeds of research then, in theory, we wouldn't have this problem. While it remains a part of a capitalist system it is inevitable.

      I'm not a communist (Honest! Capitalism has its uses and the people have a right to choose!) but it's difficult to escape the conclusion that this sort of case exposes the limitations of capitalism rather starkly.

      --

      Greg

      (Inside a nuclear plant)
      Aaaarrrggh! Run! The canary has mutated!

    13. Re:Drugs for Profit by Cro+Magnon · · Score: 1

      It won't make any difference to the people in Brazil/Africa/insert your 3rd world country. If Malaria ever became a problem in the U.S. the drug companies would develop a treatment, but it STILL wouldn't be available for the third world.

      --
      Slow down, cowboy! It has been 4 hours since you last posted. You must wait another few hours.
    14. Re:Drugs for Profit by mwa · · Score: 1
      According to the advocacy group Public Citizen (see MaineToday article):

      • Public Citizen reported that the pharmaceutical industry spent $177 million on lobbying, $65 million on issue ads and $20 million in campaign contributions in the last two-year election cycle.

        But the industry keeps its research figures secret. Public Citizen based its review on a 1991 Tufts University study that estimated research costs at $500 million to develop each new drug. Public Citizen said the figure was before taxes, ignoring that businesses could deduct one-third of the cost of research.


      They also report taxpayer-funded scientists conducted 55% of the research behind the top 5 best selling drugs. Foreign institutions contributed another 30% of the research.

      Basically, I agree that there needs to be profit to motivate R&D. There also needs to be an ethical business plan to keep the cost to patients down as well. I hope this action does not become routine ripping of drug companies' research, but I also hope it sounds a wake-up call to pharmaceutical companies' management that they had better do what any company is supposed to do; provide a good product at a reasonable cost.
    15. Re:Drugs for Profit by benedict · · Score: 2

      There's nothing to keep a government from funding malaria research, and freely licensing the result.

      I'm surprised that someone in the UK would have the peculiarly American delusion that corporations are the only entities capable of getting things done.

      --
      Ben "You have your mind on computers, it seems."
    16. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      Posting AC to keep my job...

      Another thing to keep in mind is the figures watchdog groups do not always figure in the cost to develop all the compounds (note: *not* drugs, I use the term compounds to denote it's a R&D product that may or may not ever make it to market) within a company's R&D department.

      As a tech for a company that makes research products, I've heard many of my pharaceutical customers refer to the rule of 10. This means for every ten compounds in *each* production stage, one will move on to the next level.
      Drug
      discovery is the first screening level; there's four or five rounds of testing, ranging from in vitro (pertri-dish stuff) to in vivo (animal testing, don't even get started on this) in the next level. Next is safety pharmacology (animal studies done for the FDA, making sure we can quantify the risks of using it in humans), then preclinical trials, then clinical trials.

      AFTER all that, a compound can be called a drug; it will be released to the market. Nine or so levels of testing, with 1/10 compounds moving on to the next stage.

      Of the drugs that make it, approximately one in twenty will be a blockbuster drug, the Prilosec or Viagra that makes the tons of money.

      Every blockbuster has at least 300 failed compounds'worth of R&D costs to pay for.

    17. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      But other companies manage to make drugs available for free to countries with serious AIDS problems, and still make a tidy profit from sales in developed countries.

      So perhaps there is a better balance between capitalism and humanitarianism.

    18. Re:Drugs for Profit by AlefOne · · Score: 1


      If medical research was primarily (or entirely) funded by society as a whole as opposed to by the proceeds of research then, in theory, we wouldn't have this problem.

      Right you are, Don Pardo. Everyone remembers the tremendous contributions that the Soviet medical and pharmaceutical industries made to the world, without the damning restrictions of capitalism.
      You do remember them, right?

    19. Re:Drugs for Profit by GregWebb · · Score: 2

      (Troll? Oh well, close enough to serious opinion from some that I'm biting anyway.)

      Ahem. Oh, FWIW, I have no idea whatsoever whether the Soviet medical industry made substantial contributions to science. This is reasoning why they didn't, IF they didn't.

      Firstly, they industrialised VERY quickly. This is a rather different issue from building cars and trains, and I suspect it's rather harder to get right on the sort of timescale they managed it. Yes, the Soviet Union was around for over 80 years - it was also only really industrialised for 60 of them and then at war for 10 after that. Well, a little bit during the industrialisation, out in the east, actually. Anyway. It had maybe 50 years in which to do this work, realistically. To educate the researchers (which requires at least some level of bootstrapping), to build the equipment (ditto) and to get these programs, taking many years each up and running.

      Secondly, it was never particularly rich and this isn't exactly a prestige project in a cold war situation in the same way a massive military is.

      Thirdly, it was a far from perfect implementation of this style of system with patronage and corruption both working against a truly balanced system.

      Fourthly, I said capitalism has a place! Greed might not be nice but it's a usable motivating factor when there's nothing else. I'd be delighted to see the majority of research being directed by need and not profit, but there's no way I'd stop someone who wanted to research just because they planned an eventual profit. I might restrict some of the silliness that can create (as with extreme examples like this), but that's very different.

      My simple observation is that research time and spending is currently allocated not by need but by ability to pay, which is sad and will pretty much inevitably lead to the sort of situation which started this thread. Criticising a starving man for stealing bread from those who have a surplus feels odd at a minimum and this is little different, if at all.

      --

      Greg

      (Inside a nuclear plant)
      Aaaarrrggh! Run! The canary has mutated!

    20. Re:Drugs for Profit by krmt · · Score: 2

      The thing is, a very very very large chunk of research is government funded, including research done by drug companies. That doesn't force the work to be in the public domain in the end though, it's just meant to further research as a whole.

      Perhaps if the length of the patent corresponded inversely to the amount of public money spent on the patent, then the mess would be a little less.

      --

      "I may not have morals, but I have standards."

    21. Re:Drugs for Profit by jonnystiles2 · · Score: 1

      Ah, the R&D fallacy. Do you know who holds a significant number of patents on drugs, even AIDS/HIV drugs? The US Gov. and academeic insitutions funded with a mix of public and private dollars. The patent holder then licenses the patent exclusively at a low cost to the large pharmaceutical company. The R&D argument doesn't hold water at all anymore when the marketing budget of a pharmaceutical company oustrips theur R&D budget because they have to convince everyone that weekly Prozac is now the way to go since the old kind is no longer protected by patent.

    22. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      [i]Every blockbuster has at least 300 failed compounds'worth of R&D costs to pay for. [/i]

      And despite all of that, they still manage profit margins that other industries would kill for.

      Poor babies.

    23. Re:Drugs for Profit by quisxt · · Score: 1

      [b]As proof of this, consider how many new Malaria drugs are produced? Basically, there is no profit in R&D for malaria, so drug companies simply don't bother.[/b]

      This is true for most tropical diseases. If your are unlucky enough to travel in the tropics and come back with malaria, chagas dieseas, leishmaniasis, denge fever, or something similar, you will get to experience first hand just how few drugs are out there. Brazil's move ensures that in the future even less R&D money will be invested in tropical medicine.

    24. Re:Drugs for Profit by geekoid · · Score: 2

      By your logic, no one would have ever done any research to cure medical problems before the patent system was instituted.

      Patent controlls on medicine are needed by theses companies so when they bury a cure in favor of a treatment, they can rest assure no one can have a cure, while they rake in the dough on treatments.

      do you think a company that makes billions on insullin treatments would sell a cure?

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    25. Re:Drugs for Profit by aprentic · · Score: 1

      A) Drug companies do get paid for R&D (see grant money)

      B) There's already a treatment for malaria.

    26. Re:Drugs for Profit by Anonymous Coward · · Score: 0

      Malaria?
      Wnat to know who produces the more eficcient malaria vacine? The same brazilian federal laboratoriy that produces all the generic AIDS drugs Brazil's govt. distributes..
      My opinion is that in some areas of science, and drug research is one of them, the responsability for most of the funding should be PUBLIC, not by a private lab.
      Health, education and security concern for the State.

  26. Re:India, Brazil, China... half the planet already by Anonymous Coward · · Score: 0

    > Things shape up on the "our money vs. their life" front.
    > Medicine has been corporate property for far too long already.

    This is a wonderfully idealistic view of the world, but woefully out of touch with reality. Pharmacueticals are incredibly expensive to develop. If other countries follow Brazil, then you're cutting the financial backing for R&D. Say good-bye to most any hope for an AIDS cure, to mention nothing of Parkinson's, Alzheimer's, and a good number of other diseases. Sure, government-funded research will continue, but by destroying a pharmacuetical company's R&D budget, you'll be drastically slowing down the rate of medical innovation.

    If countries truly care about fostering medical innovation AND providing care to those who need it, they would subsidize the cost of prescription medicines. Pharmaceutical companies would be able to recoup their huge R&D investments and patients would have access to low-cost medicine. But this would likely require raising taxes... and that's a whole other topic of discussion.

  27. Aid companies by The_Jazzman · · Score: 1

    Really are the scum of the universe.

    This is the kind of information that should be free. What if someone were to decide to patent the AIDS bug ? If you were to be infected with it, could you be charged for violating their IP and therefore have no alternative but to buy the cure off them ?

    Maybe this is a viable business plan that I should attempt !

  28. three cheers for brazil by Anonymous Coward · · Score: 0

    i think more countries should follow suite. i'm really getting sick of commercialism when it's placed before human rights.

  29. finally official by jpostel · · Score: 1

    This was predicted several months ago in the pharmaceutical industry. They are even MORE concerned about this happening in countries in Africa. The countries that have the highest rates of AIDS will likely start manufacturing and distributing drugs to not only people in their own country but to other countries as well.

    I doubt that it will hurt their profits in the short term because they don't sell huge amounts of the drugs in the poorer countries anyway, but it sets a (dangerous) precedent for other countries to follow. The point that some people seem to miss is that if they fail to adequately QA the drugs, most of the people will die anyway. Making drugs is not as simple as getting a formula and mixing up the igredients. This is not baking cookies.

    The Brazilian government needs to look at addressing problem by preventing new cases of HIV also. They need to promote safe sex and maybe start distributing condoms and disposable syringes or something.

    Either way, this is a sad situation.

    --
    Ummm, Jon, aren't you supposed to be dead...? - Otter(3800)
    1. Re:finally official by Anonymous Coward · · Score: 0

      you are a sad little ignorant fool.

      Maybe if you bothered to find out a little bit about brazil you would have learned that they are running one of the most sucessfull and largerst public AIDS education campaigns.
      The figures quoted were they expected to be at 1.7 million aids patients, but due to the agressive awareness campaign only around 500K people suffer from it.

      The brazilian government has looked at and adressed the problem to the best of thier ability.

      It's sad so much ignorance is present in this /. discussion. If people would educate themselves a bit before they spout off, it would be a better place.

    2. Re:finally official by jpostel · · Score: 1

      I might be falling for a AC troll here but...

      I think you missed my point.

      I am sad about AIDS, but I am not little. I am ignorant about Brazil, but I am not a fool.

      My point about mentioning the US and Europe was that AIDS does not care where you live, and neither does ingnorance. Education about HIV and AIDS has not stopped it in the US and Europe. I don't doubt that Brazil has done something about it, but the idea of quarantine was over the top.

      That was my point.

      --
      Ummm, Jon, aren't you supposed to be dead...? - Otter(3800)
  30. Whoa, by Anonymous Coward · · Score: 0

    This must be the biggest nation-scale "fuck you" to another big entity (without a war) I've seen in a long time...

  31. Are you for real? by codeforprofit2 · · Score: 1

    "...important example that public needs justify the disregard of patent protection."

    If patents can't be enforced we will not see much more research&development for deceases.

    Do you have any idea at all what the development costs are for this kind of medicines?

    Patents as a concept is very important for all economies all over the world and should not be confused with the abuse of patents in the US where to broad and/or to obvious patents are granted.

    1. Re:Are you for real? by Trinidad_T_Tobago · · Score: 1

      Did you work for MicroSfot?

      I hear speech like that sometime ago on their site....

    2. Re:Are you for real? by Anonymous Coward · · Score: 0
      If patents can't be enforced we will not see much more research&development for deceases.

      In my local supermarket I can buy bread, bleach, baked beans, soup, plastic bin-liners, pasta, etc. etc. The amazing thing about this is that none of these products are patented. By some of the reasoning we've been seeing in this discussion, the companies producing this stuff clearly can't be making any money without patent protection, and therefore must be making these products solely for the public good. What great guys, eh?

    3. Re:Are you for real? by SlippyToad · · Score: 2
      If patents can't be enforced we will not see much more research&development for deceases.

      I hope not. We have enough deceased as it is. If you meant "diseases," though, I think you're overstating your case. There are plenty of people who would fund research for a cure for various "deceases." I don't, however, feel like funding, even as a consumer, most of the treatments. I'm diabetic. I was, until a few months ago, taking one of the latest diabetic drugs on the market at a pretty hefty premium. Actually, my insurance company was paying for it. Anyway, after a lot of experimentation and consultation with my doctor I decided I would try to control my sugar with diet. Well, two months later and I'm doing fine. I'm pretty lucky, but I also think it's revealing that I can do for myself with some self-control what the drug was doing for me. Yeah, the drug companies spend a lot of money, creating medicines that we may or may not need. Maybe the system isn't doing exactly what we need it to do.


      Do you have any idea at all what the development costs are for this kind of medicines?

      More importantly, do you? I hear a lot of numbers. They often smell like they've been freshly pulled from someone's ass. What does it actually cost to develop a treatment for AIDS?

      Patents as a concept is very important for all economies all over the world

      I'm becoming increasingly skeptical of this. I would be happy to hand over tax money to fund medical research in the public interest. Again, for a cure. I think we're being sold one treatment after another because it's a long term strategy for the survival of drug companies. That isn't working for the best interests of people like me (and believe me, Diabetes can be just as fatal as AIDS if left unchecked. It's just not as scary). There are a lot of assumptions in your argument that just don't pan out. Medical research got done long before there were medical patents. Presumably there are people who have a slightly wider focus than the checkbook in front of them.

      --
      One day I feel I'm ahead of the wheel / the next it's rolling over me / I can get back on / I can get back on
  32. Difficult... by Asic+Eng · · Score: 1
    Well, nobody can fault you for trying to save your life, that's for sure. So I can understand the Brazilian government (and others in the same position). Obviously it's not right to prevent someone needing a drug from getting access to it.

    On the other hand, developing a new drug costs extraordinary amounts of money, the companies who are in the business of making them deserve their reward, too. Someone needs to pay the bill, it's not entirely fair to stick these companies with it. After all, the work they do there is very valuable. There is also the danger, that that loss of profits would decrease the effort which goes into AIDS research.

    It would be nice if some developed countries would be prepared to finance part of the drug costs - obviously the pharmaceutical companies would have to be expected to be reasonable in their demands, too.

  33. Here's my complaint about drug patents by Microsift · · Score: 1
    Drug patents delay innovation. Consider Prozac, a drug which help revolutionize the treatment of depression. Recently, the company's patent expired, opening the way for cheaper generics. If you've been watching those annoying drug company ads on TV, you may have seen an ad for a Prozac that can be taken just once a week. This drug would have a new patent, that will expire in several years. It seems too great a coincidence that as the company's patent for a drug was expiring, they finally figured out how to make the drug more convenient to take.


    Given that some people who need to be on Prozac may not be able to remember to take the drug every day (at least initially) it seeems immoral for the company to delay the introduction of Prozac Weekly until the original patent expires, this may have actually harmed people!

    Drug companies should have an opportunity to recoup the cost of research, but the cost of this opportunity should not be the health of patients.

    --
    My other sig is extremely clever...
  34. Say bye-bye to any new AIDS drugs by NineNine · · Score: 3, Redundant

    Well, that's probably going to be it as far as new drugs in the fight against AIDS. Drugs cost millions (billions?) to develop and test and distribute. If other companies are going to allow these patents to be violated, there's virtually no incentive for drug companies to develop any new drugs to fight AIDS. So yeah, Brazil and other countries who adopt this tactic may get some short term gains, but long term, it's going to kill AIDS patients. Literally.

    1. Re:Say bye-bye to any new AIDS drugs by MongooseCN · · Score: 2

      What, so no one is going to produce an AIDS drug because there might be competition? That would be like saying a car manufacturer won't create a car because they don't hold the patent to 4 wheels and an engine. If a pharmacutical company doesn't have a monopoly on a new drug, they will just have to compete with other companies, by offering lower prices, better quality drugs, better service. There are many other ways to compete than to just have a drug itself.

    2. Re:Say bye-bye to any new AIDS drugs by bradasch · · Score: 1

      So what you're saying is that new drug research can only be done by big drug companies (because it costs million (billions?)), and that if these companies don't get their "deserved" profit (because other companies will violate their patents and make money), they're going to stop developing new drugs (and thus stop increasing their profits)?

      I don't think so. IMO, drug companies that have huge profits (and they have huge profits, believe me) can easily handle this. If they can't, it's about time to move R&D of new drugs out of the companies, to, say, universities.

      Sometimes making money isn't the most important issue.

    3. Re:Say bye-bye to any new AIDS drugs by dswan69 · · Score: 1

      They make all their money in wealthy countries. Only the truly gullible believe anything the industry has to say.

    4. Re:Say bye-bye to any new AIDS drugs by NineNine · · Score: 2

      This isn't anything close to competition. Roche has to 'compete', as you call it, with a company that has zero R&D costs. R&D is the primary cost of any drug company. That would be like me copying a bunch of OReilly books and selling them onthe streets for $5/apiece. That's competition, right?

    5. Re:Say bye-bye to any new AIDS drugs by Gorbie · · Score: 1

      While I agree with your general sentiment, AIDS kills AIDS patients. These drugs do not prevent death, they prolong life. In the end, the people will die, and from AIDS.

      The drugs that are in question are not a cure for aids, they just delay and suppress the effects. There is no cure. For the time being, the HIV virus remains unkillable.

      With all this in mind, I agree that the breaking of the patents is a bad thing. Drug companies need financial incentives to continue to develop drugs. Maybe there is a better system somewhere, but until it exists we should undercut the current one. It we take the wind out of the sails of the researchers, we may never find a true cure to the disease!

    6. Re:Say bye-bye to any new AIDS drugs by jonnystiles2 · · Score: 1

      That argument could use a cross reference with this article. If you read this article, you will see that the drug provided by Roche was one drug in a 12 drug cocktail, yet accounted for more than 25% of the cost of the total cocktail program.

    7. Re:Say bye-bye to any new AIDS drugs by vanicat · · Score: 1


      If other countrie are going to allow these patents to be violated, there's virtually no incentive for drug companies to develop any new drugs to fight AIDS. So yeah, Brazil and other countries who adopt this tactic may get some short term gains, but long term, it's going to kill AIDS patients.


      do you realy believe that rich conutry will do this ? i dont't. I've recently read that 10% of the world population have 85% of the consomation power. Most of this people are in rich country. So until USA and Europe don't do this, most of the incentive for research will still be there.

    8. Re:Say bye-bye to any new AIDS drugs by Anonymous Coward · · Score: 0
      That would be like me copying a bunch of OReilly books and selling them onthe streets for $5/apiece.


      No it isn't anything like that, you dumb fuck.


      The Brazilian government is giving away the drug for free to people who could not have afforded to buy it in the first place! That means, to anyone with an IQ over their shoe size, that the market never existed there in the first place.


      This hardly affects the drug company at all. They have plenty of idiots like you who will get sick and have the money to payfor the drug to prolong their miserable little lives.

  35. But its done with Govt money by Anonymous Coward · · Score: 0

    Did you know that the reason Brasil has one of the highest AIDS infrction rates that it is one of the most promiscuous countries on the face of the earth? Its bullshit that the government is foorting the bill for the people irresposnsible actions. Except in a few rare cases (blood transfusions, medical accidents) 99% of all HIV cases got that way from their own personal actions. No freaking way should the taxpayers have to pay for that. Those responsible should foot that bill,and if they can't foot it, let them die.

    1. Re:But its done with Govt money by cornboy · · Score: 1

      Ooooh, the personal responsibility argument. Buddy, you are so full of bs. Fine, let's take your argument another step or two logically. Since the government shouldn't foot the bill for anything that results from personal actions, then we should stop paying for treatment for a lung cancers (a result of smoking, a personal choice), all maternity benefits and infant care (after all, if you hadn't had sex), all medical treatment for automobile injuries (if you hadn't been driving the car you wouldn't have been hurt)...blah blah blah. We could make a long list of what shouldn't be done then that won't be covered, if you use personal responsiblity/personal actions as your standards. I'm sure something that you do would be on that list... The fact is, sex is an intregal part of human nature. Outside of the pope, everyone pretty much does it. Has been that way, and likely always will be. Having said that, you must realize that NOTHING will 100% protect you (other than complete abstinence) from HIV. Some things are pretty good but nothing is 100%. Until that changes, government should do all it can to stop this epidemic. You should educate yourself before you make really ignorant and damaging statements like your post. How sad.

  36. Good! by Neorej · · Score: 1

    Break all this patent crap, this is for the good of everyone, finally a government thats acting sensible. I can understand people or companies want to get credited for the work they did but this shouldnt be taken too far.

    It might be an idea to have the United Nations give the company (that holds the patents) large sums of money in order to stimulate further research in the field. That way they'll be happier too.

    Now all we have to wait for is a government that states Shell (or whowuzzit) can shove those patents for the water powered engine up their **** because they're going to ignore them anyway.

    --
    -- Si hoc legere scis nimium eruditionis habes.
  37. Save money, not necessarily lives by SuperBigO · · Score: 1

    According to the article, the motivation for breaking the patent is to save the government money (40% of $82 million) and not necessarily to save lives. The government was getting all the medication it needed, but wanted to pay a lower price.

    In Brazil, the government provides free treatment for AIDS/HIV infected people.

    I think that this sets a bad precedent and should not be applauded. I see it the same as the government seizing the property (Intellectual Property in this case) of a Corporation for what they claim is a public benefit.

    They could seize the property of any company or individual and say that it would be in the public's interest because it saved them some money or because the individual or company did not do what the dgovernment wanted them to do.

    This is the way that dictatorships starts and individuals and corporations lose their rights: with the government abusing their police power and the citizens supporting it because it helps their pocketbook.

    1. Re:Save money, not necessarily lives by Trinidad_T_Tobago · · Score: 1

      THink on this side.
      YOU are a HIV holder.
      YOU have NO money.
      YOUR country have no money.
      Roche say : sorry.

      Put this shoes and walk a light year.

    2. Re:Save money, not necessarily lives by Anonymous Coward · · Score: 0

      I think this story underlines the true problem with the whole pharmaceutical industry. We cannot blame a corporation for trying to make money. It is the underlying principle of all corporations... to increase value for their shareholders and therein lies the problem. Pharmaceutical companies DO NOT act in the best interests of humanity. It is not their creed. Profit over lives. Therefore they should not be the ones behind these drug "innovations". My belief is that we need an international group of scientists, with heavy funding from all industrialized nations to develop drugs for the benefit of society, an organization that does not innovate with the premise of "Profits first". It is because of this "Profits first" idea that we cannot allow them to develop drugs for us... Simply because they DO NOT INNOVATE FOR OUR BENEFIT!

      Let's look at a simple example. What would a drug company rather develop? A cure for AIDS or a drug that allowed to to live with the ailment provided that you kept taking the drug. If a pharmaceutical company acted with our best interests at heart, they would press for a cure. But because "Profits First" is the rule of the day, and because this is the premise of any corporation, they owe it to their shareholders to create the latter and with it a generation of dependant drug-users.

  38. This is not good by mESSDan · · Score: 1

    This sets a very unhealthy (no pun intended) precedent for Drug companies. If this is not met with swift legal action, this will not stop with Brazil.

    I can see this as being very difficult to persue, with the US dropping its suit with the WTO and the UN praising Brazil for its "Free Drug" policy.

    I guess one thing is for sure, it sure does suck to be Roche right now.

    --

    -- Dan
  39. The Dark Ages by Jaysyn · · Score: 1

    I wonder what would have happened in the 14th - 15th century if some had a cure for the black death, but wanted insane amounts of money to even talk about it. They would have probably tortured it out of them. Pharmacutical companies should consider themselves lucky....

    Jaysyn

    --
    There is a war going on for your mind.
  40. Thats nice, but . . .. by utdpenguin · · Score: 1
    Veyr nice and all you can be sure.

    But why the hell was my story abotu the new Code Red Mountain Dew slurpies at 7-11 rejected?? they rule!!

    --
    In Soviet Russia you dant have to put up with these crappy jokes
  41. Re:Of course they fight AIDS by CmdrTaco+on · · Score: 0

    Sorry, I meant 'They're' not 'Their'. But was that a reason to mod me down to troll? Damn homo grammar-nazi mods....

    --

    saru mo ki kara ochiru

  42. Patents over human life? by jlemmerer · · Score: 1

    Hi Everybody..

    IMHO patents on medicine should generally be forbidden. I am of the opinion that human life should be protected by all means possible and it is no moral justification that companys make more money on the cost of patenting (and by doing so killing) people.
    Of course the pharma producers must earn money, but to withhold vital medicine from dying people because of money is sick.

    go on Brazil... hopefully other countrys will follow.!

    --
    ".Sig Stealer" was here
    1. Re:Patents over human life? by Psion · · Score: 1

      jlemmerer,

      What will happen to drug research then if you get what you want? The pharmaceutical industry funds its research with patents on new medicines. Take away the patents, and the companies won't have any money to research new drugs. Drug companies will be forced to stop R&D and instead churn out old products. That would mean no cure for AIDS, cancer, etc. This tactic might be politically sound right now for the handful of Brazillians who have AIDS today, but to gain that, it runs the risk of sacrificing orders of magnitude more people in the future.

      Is that what you want?

    2. Re:Patents over human life? by jlemmerer · · Score: 1

      i do not want to rip the companies off their profits. it would be better for the development of new threatment if all the medicines would be freely available, and the funding fome by, e.g some international agency. i know that this is only a illusion and the current system is better than nothing, but joint forces on threats like AIDS and Ebola would certainly better than everybody working in secret so that competitors don't have a chance to react

      --
      ".Sig Stealer" was here
  43. AIDS is not an indiscriminate killer by Anonymous Coward · · Score: 0

    The fact is that people that have AIDS have it as a result of immoral behaviour. The progression and impact of such diseases is a form of natural selection. Natural selection has moved beyond fitness/strength. We are now in the realms of a natural selection based on intellect and morality. If you lead a moral life and do not abuse your God given body and mind, then you have nothing to fear. Simply avoid drugs, gay sex and others that participate in such activities. We will inherit the Earth.

  44. This is a very shortsighted move by CptSpiffy · · Score: 1

    Many of you may feel that Brazil is doing the right thing here, and I must admit to a certain satisfaction as well, but there is more to this issue than "life is sacred, you can't put a price on it, etc.." These companies spend BILLIONS developing these drugs. What fuels this research? PROFIT. Helping people is great, but these companies are in BUSINESS. If governments simply start TAKING them, then what is the incentive to research new drugs? Don't discount the importance of this decision; if other countries try to follow Brazil's lead with this, you WILL see a reduction in new developments in private AIDS research. This already happened with malaria drug research, so there is a precedent. Personally, I hope the WTO comes down on Brazil like the Wrath of God, to discourage other countries from attempting this. This kind of short-sighted move is the kind of thing that critically slows down drug research. Like most of you, I beleive protecting it's people is the most important goal for a government.. but with millions dying anually fron this disease, can we afford to delay a cure? Capitalism is a dirty business, but it's the reality of the world we live in.

  45. excuse my stereotypical ignorance by Lord+Omlette · · Score: 1

    Doesn't Brazil have a high AIDS rate because the men are too macho to use condoms and the women won't insist on it? I think if they can change that, they have a shot at containing the problem which would make AIDS drugs that much more effective... Otherwise it's like trying to use water to put out a fire while someone else is pouring gasoline on it or something.

    --
    [o]_O
    1. Re:excuse my stereotypical ignorance by Anonymous Coward · · Score: 0

      In some ways, it is far worse than your analogy. No HIV/AIDS treatment actually cures the disease, but merely makes it possible for them to live longer after becoming infected. I fairly sure that a person on these drugs is still capable of transmitting the disease to someone else. Since it is unlikely that behavior will change once the drug is made available, these people will live longer while still acting in a manner which makes them an ideal vector for HIV. The net result will be higher and higher infection rates. In the end, everyone will wind up paying more and more to treat the ever increasing number of HIV infected individuals.

      In my opinion, this is the worst thing about the Brazillian plan. The theft of IP is pretty insignificant when you stop to think about it. It also makes you wonder if HIV treatments are actually a good thing, in light of the nature of the disease and the way it is transmitted, until there is a cure.

  46. A few points by Remote · · Score: 2

    After reading a few posts stating that there's the danger of such actions disencouraging research, I would like to add:

    - The law says that the gov't can issue a compulsory license, which doesn't mean public domain or copying the process for free, but gives the power to the state to set the terms of the license. This is consistent with a constitutional principle that public (not gov't!) weel-being is more important than the weel-being of a few individuals.

    - The law also sets a period after which this compulsory licensing can be done. I'm not sure whether it's 2 or 3 years, but should aloow for a reasonable pay-bak period.

    - According to the Boston Globe article, a ptient in Brazil costs US$ 350.00, while the same tratment costs US$ 10,000.00 in the US. Clearly, there's plenty of margin for cutting.

    Other few points people maybe should be aware of:

    - Health Minister José Serra most definitely has an eye in next year presidential elections.

    - It is illegal for individuals and private companies in Brazil to trade AIDS medicine, except for selling to the gov't. My brother died of AIDS in 97 and my mother ended up with a big supplt of DDI, which she returned to the health service. She would have done that anyway, but imagine the kind of abuse that would take place if you could obtain medication for free and trade it.

  47. You know, the likely response is going to be. . . by Salgak1 · · Score: 1
    . . . going TOTALLY private with the IP. And filling the pills with lots of wild-tangent-generating substances to send copycats off on multiple directions... Or worse still, finding a way to COPY-PROTECT a pill. . .

    Concept: I see a capsule, that if broken open or exposed to air, would chemically change the contents. Is it possible ? I have no idea. Will the Pharmaceutical Companies look ? That's a sucker bet: they're probably ALREADY looking at it. . .

    Nice job, Brazil. You may have won this battle, but you just lost the war. . .

  48. Capitalist pigs or unrealistic socialists? by nihilvt · · Score: 1

    This is all well and good, but before we start heralding this great advance against capitalist pigs we need to watch out. I think decision displays the best of intentions. But what does this mean for future advances in medications for crippling diseases? Those diseases and medications cost INCREDIBLE amounts of money to research. What happens if a company fears that it cannot recoup the money invested in R&D? No more research on these diseases. Longer R&D cycles. Less efficiency. Less incentive. No more new helpful medications. It's a hard decision. Do you want relief immediately, or more effective relief later? Do the ends justify the means? I don't know. But I don't want a stagnation in medical advances because everyone starts to decide they can ignore patents.

  49. disregard for patent laws prevent new drugs by Pov · · Score: 1

    Sure, what Brazil is doing sounds like a great and humane thing to do for all those suffering from AIDS without enough money to pay for drug treatment, but consider what the long-term effects of this are. If you eliminate the profit of selling the AIDS drugs, then the companies that spend millions and millions of dollars on research and development will stop doing it.

    Where do you think they're going to get the money to research a cure or a vaccine if they can't sell what they've got now?

    This may be great for the people currently suffering from AIDS in Brazil, but it's a tragedy for those who will suffer in the future and across the whole world if the money they're leaching might have contributed to a cure or a vaccine.

    --
    --- Don't be a player hater: I meta-mod ALL negative mods as Unfair.
  50. Exactly. by Anonymous Coward · · Score: 0

    Sweden is one example of a country who tried to screw companies (with lontagarfonder and other un-honest criminal shit pulled off by the government), look where it got it. One massive, huge financial meltdown in the early 90's making each Swede with a debt of about $15 000.
    The primary reason was that the companies (and their money) fleed the coounty) and not much taxes where payed anymore

    You are ALWAYS held resonsible for what you do sooner or later. Sure it way seem to be good to take other peoples huge investment and give it away without paying for it right now but not many new investments will be made. That means no new solutions to cancer, parkinson and other deceases.

  51. Easy resolution by Wolfier · · Score: 1, Troll

    Lower your prices, or we'll use 10% of our AIDS budget to send people to your country and have sex with your people. Hehe

  52. Patents != Bad by nahdude812 · · Score: 1

    I agree with Brazil in this matter, people are dieing due to a patent on a daily basis, this is a clear cut case where a patent violation is in the sake of humanitarianism.

    The problem here though is this: patents exist for a reason, and it's not necessarily to let patent holders get fat pockets and laugh their way to the bank at the misfortune of the poor schmoes who have to shell out for the patented product. Especially given pharmaceuticals, the reality is (I've been an IT guy in pharmaceuticals since I was 18, and my mother has been a scientist working for them since she graduated college) that developing drugs for use in humans costs billions of dollars. I'm not exaggerating, billions, even if you only wanted to get a different kind of sugar pill approved, billions. The studies take many years, the insurance costs once you enter the clinical phase (testing the drug in actual humans) are amazing, there are hundreds of people working on the target drug the whole time, and these are people who make $50,000 for the simplest tasks, let alone when you get a pathologist, who may well make several million a year (pathologists are to doctors what doctors are to us, the go to school for twice as long. It was discovered that one of the pathologists at my company made more than one of the executive board). There is not a company in the world that has the capacity to fork out billions of dollars in research for a drug, then sell it at cost, or slightly above cost. They need to make up this capital, as the drug industry is like a loaded version of Vegas... more likely than not, you're going to get burned, except that the issue here is the continuation of your company, and jobs for all of its employees.

    If we go willy-nilly violating patents on drugs, companies will stop researching drugs, as they are guaranteed to take a bath if they cannot control the market early on. The people who produce drugs outside of the people who research that drug have comparably next to zero cost in the production, they operate with out overhead, and as a matter of fact, the percentage pure profit on generic drugs (when compared to total sales of a drug by the pharmaceutical who researched it) is tremendously greater.

    If you take away a company's ability to control their product after so much initial overhead, they won't do it, because in the end, regardless of any humanitarian mission statement, companies are there for one reason... to bring profit to their stockholders. If the stockholders are not getting a profit, they'll sell, and the company will go under, and now there's no AIDS drug at all, instead of an expensive one (assuming that the company closed prior to research completion). You can't create a company with the expectation to lose money like that, you simply won't get investors.

  53. On the other hand... by why-is-it · · Score: 2

    if people circumvent the intellectual property rights of drug companies, the result is less money for research, less new drugs, and ultimately less lives saved.

    If we respect the intellectual property rights of Big Pharma, the result will be huge dividends for their shareholders and the deaths of many innocent people who just could not afford to stay alive...
    Naturally the rights of the shareholders to expect a good return on investment must trump the rights of the impoverished...

    --
    *** Where are we going? And what's with this handbasket?
    1. Re:On the other hand... by taliver · · Score: 1
      So there's this story about the hen that laid golden eggs...


      It seems that the farmer that owned it wanted the eggs NOW. The eggs were coming way to slow. He just couldn't wait.


      The farmer decided that he could probably get a hold of a couple of eggs inside the hen if he killed it. So he did. And just for the argument, let's say he found two more eggs.


      Now, why in the hell would any more golden-egg laying hens come to that farmer?


      In the same light, why in the hell would I spend millions to make a cure just so somebody could come and take it from me. If Brazil wanted to do it right, let them fund the entire research effort, and then let them do whatever they feel like with the drug.

      --

      I demand a million helicopters and a DOLLAR!

    2. Re:On the other hand... by dinivin · · Score: 1


      A hen that lays golden eggs? Let's try to get back to reality here, OK?

      Dinivin

    3. Re:On the other hand... by Anonymous Coward · · Score: 0

      All the "now there will be no more drug research" posters fail to understand that much research is done in universities (basic stuff that pharmas help fund, and later patent) and mostly paid for by tax dollars. Yah the pharma companys pay as well, also there are the tax breaks to take into account.

    4. Re:On the other hand... by taliver · · Score: 1
      Fine, they get money to do research, but if a company doesn't make money from a drug, they aren't going to produce it, or even want to start research in that are.


      And like I said, if a government wants to fund the research efforts entirely, go for it. And whenever a company and the government fund university research, there are agreements before they start saying what pantents will belong to whom.

      --

      I demand a million helicopters and a DOLLAR!

    5. Re:On the other hand... by Anonymous Coward · · Score: 0

      Much research in 'cultural studies' and other bullshit is done in Universities.

      And loads and loads of empire building.

      Even a little science from time to time.

      I'd sure hate to rely on them for the development of new drugs, however.

    6. Re:On the other hand... by Anonymous Coward · · Score: 0

      Why don't you back that up. I'll bet you can't.

    7. Re:On the other hand... by Anonymous Coward · · Score: 0

      DDT is no longer the chemical of choice for killing skeeters. Permethrin works better and is safer on the environment and the people exposed.

      Get outta the 50's! maaaaaaaaannnnnn!

    8. Re:On the other hand... by jjoyce · · Score: 1

      It doesn't matter if they don't want to produce it. What we're talking about here is use of the recipe.

  54. South Africa Did The Same and Got Screwed by Lexias9 · · Score: 1

    South Africa did the same thing in the early '90s and got their asses embargoed by the wonderful U.S. of A. In fact, Al Gore was the man behind this, with one of his main advisors being an ex-drug company lobbyist.

    It was much cheaper to produce the drugs domestically but the drug corporations didn't like that. Screw the sick and dying, we want our money damn it!!

    Here is a link with more info:

    http://www.motherjones.com/mother_jones/JF00/AID S_ drugs.html

    I guess the drug companies should follow the example of entertainment. Patent the coating on the outside of the pills so that if anyone breaks open the pill to examine the contents to provide alternatives, sue the living fuck out of them.

    I also know that one of the administrations top people is a college buddy of his Brazilian counterpart. A little back scratching?

    It's cold in here......

    --
    "Dude, your Octanes on fire."
  55. Value of Law? by Wordsmith · · Score: 1

    I hate patents as much - no, make that more than - the next guy. I have a basic objection to the idea of intellectual property. I don't believe ideas can be owned, no matter how much work goes into producing and communicating them. BUT - Brazil has established a patent system, and declared this patent valid. To go back on that simply because it's convienient - or even because of extreme duress - speaks volumes about Brazil's respect for its own laws and procedures. Imagine if we applied this logic to other scenerios. You can't choose whether to respect the value of law on a case-by-case basis.

    Brazil has established that its law now works this way: Follow the law, unless you have a really really really good reason to want to break it. THat's a disasterous way to run a county. It makes the law itself useless.

    Now, if brazil wanted to dismantle it's patent system entirely through due process, I'd be all for that. But that's not what's going on here. Selective rule of law is.

    1. Re:Value of Law? by JCCyC · · Score: 2

      Bzzzt. Thanks for playing. Brazil hasn't broken any law here, not our own (I'm Brazilian in case you haven't noticed), not anyone else's. We applied the Compulsory License law, which says the Govt has the power to "force" a licensing to a third entity in cases of abuses that damage the public interest.

      In this case, the licensee is the Oswaldo Cruz Foundation (state-run medical research center). They, and they alone, have now the right to manufacture the concoction in addition to Roche.

      That's right, the patent is still valid and in full effect. I'm not the licensee, so if I go and make and sell the medicine I can be sued by Roche, and the Brazilian govt won't do a thing to stop them.

      To say that Brazil trampled Intellectual Property, therefore, is megacorp-inspired FUD.

  56. but alas, the WTO by flashpoint · · Score: 1

    this is one brave and seriously laudable move ob behalf of Brazil, as the WTO could levy massive sanctions against them for this action. for those who don't know what the kids in Seattle were fighting in the streets over, the WTO is a transnational body-- a meta-government, if you will-- that is capable of coercing states (basically by suing them) out of erecting "barriers to free trade." a "barrier to free trade" is essentially any national law which presents any sort of a hindrance to international commerce. disregarding international patent conventions falls under this category (as does elements of Amercia's Endangered Species Act and our ban against importing British beef, as the WTO has taught us in the past).

    see (R)TMark's http://www.gatt.org, a very honest parody of wto.org, for a more on the WTO.

    the political fallout of a WTO action against Brazil on behalf of Roche would probably make Seattle look like a playground skirmish, so maybe the WTO might just back down. not that they've backed down in the name of human life before....

    we'll just have to see to that.

  57. Duesberg by Anonymous Coward · · Score: 0

    This is all BS. The details are at http://duesberg.com/

  58. Thank You Brazil by BroadbandBradley · · Score: 2

    we need more gonvernments who put the people first and not the corporations.IMHO this reflects well on your people and culture, and the ethics you hold.

  59. The Way Things Actually Work by Drakantus · · Score: 2

    This is they way things actually work. The world we live in is mostly created through artificial laws and regulations that have no real basis in reality. Intellectual property? Yeah, whatever. If the drug is so simple to recreate that the government of brazil can do so without assistance from the drug's owners, so be it. When did Brazil's citizens agree to go along with IP Laws?

    --
    I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    1. Re:The Way Things Actually Work by sql*kitten · · Score: 2
      If the drug is so simple to recreate that the government of brazil can do so without assistance from the drug's owners, so be it.


      Everything's easy once someone else has done it first. Why did it take thousands of years for humanity to develop electrical power, when you can walk into any corner drugstore in the world now and buy a pack of batteries? Do you see where I'm going with this?


      When did Brazil's citizens agree to go along with IP Laws?


      Are you trying to say that you believe it's OK to simply ignore any law that you don't agree with?

    2. Re:The Way Things Actually Work by Drakantus · · Score: 1

      Are you trying to say that you believe it's OK to simply ignore any law that you don't agree with?

      Yes.

      I believe even criminals believe in the majority of the laws they are breaking, I mean do you really think a thief wants to have his own things stolen from him? On the other hand there are laws that were never created by the people, and do not benefit the people, there isn't much reason to follow them.

      --
      I love going down to the elementary school, watching all the kids jump and shout, but they dont know I'm using blanks.
    3. Re:The Way Things Actually Work by pkesel · · Score: 1

      Hurray! Another wizard who's cornered the market on reality! Get a grip.

      Your idea of reality means that the cash in your pocket is really only paper with a bit of ink, and it's not really worth the potatoes in your pantry, so you should really be out collecting grubs and tubers to feed yourself. Maybe you'd convince your employer to pay you in chickens and rice? Or maybe you're not old enough to have to support yourself in the 'real world' yet.

      --
      - Sig this!
  60. Patents are theft by Improv · · Score: 2

    Information and data cannot be owned -- they
    lack scarcity, and to grant a monopoly on a single
    idea is to steal from the potential of every
    single person on the planet. The mere fact of
    investment does not entail a responsibility for
    returns. Or do you see competition as theft?

    --
    For every problem, there is at least one solution that is simple, neat, and wrong.
    1. Re:Patents are theft by Erasmus+Darwin · · Score: 3, Insightful
      "The mere fact of investment does not entail a responsibility for returns."

      If we don't provide some sort of protection, there won't be any incentive for people to invest in the first place. Would Roche have devoted the money necessary to develop this drug if anyone who is capable of manufacturing it could do so? Hell no. This drug has saved lives (well, extended them, at least -- which is all any drug can really do). This drug would probably not exist if it weren't for patents. QED...

    2. Re:Patents are theft by Baki · · Score: 2

      Then please let them stop inventing. This will leave a gap that others can take over.

      Others will take over. Public matters such as health should not be in the hands of companies IMO. Producing the drugs can be left to companies, but inventing them is research of public interest that belongs to non-profit organizations such as universities.

      That costs money, but just look at the vastly increasing amount of money that medicines take in the health budget of most nations (either privately paid as in the US or paid from tax money as in most other countries, it doesn't really matter). It would be better to save this money (of which 50% or more is spent on advertisements!) and put it directly into non-profit organizations who would make better use and be more efficient.

    3. Re:Patents are theft by MartinG · · Score: 2

      &lt SARCASM&gt Oh... like theres no incentive for companies to write open source software you mean?
      &lt/SARCASM&gt

      What you say sounds perfectly resaonable, but there is very little real evidence to suggest what you say is true.

      Whatever the reasons, experience is showing us that people can and do make a living producing and selling products that can be and are openly copied (and hence more often improved - but thats another argument)

      I'm afraid your argument is one based purely in the fear of what might happen and not on real life facts.

      --
      -- MartinG To mail me: echo kewyjlcxyzvjfxbqwh | tr bcefhjklqvwxyz .@adgimnoprstu
    4. Re:Patents are theft by Phil-14 · · Score: 1

      Compare and contrast the progress air travel,
      which had heavy private involvement, has made
      this century, with the progress made by space
      launch, which was mainly developed and is dominated
      by the government. They're still flying cargo to
      ISS at $ 5000/pound or more with the Space Scuttle.
      Is that really what you want pharmaceuticals
      research to look like?

      --
      (currently testing something about signatures here)
    5. Re:Patents are theft by crealf · · Score: 1
      Compare and contrast the progress air travel, which had heavy private involvement, has made this century, with the progress made by space launch, which was mainly developed and is dominated by the government.

      The space technology looks way better.

      They're still flying cargo to ISS at $ 5000/pound or more with the Space Scuttle.

      So ? Shipping 1 pound from this side of my building to the other side is way cheaper than all those costly $$$ airplanes. This is sure because those inefficient planes are build by bureaucratic companies which try to suck as much money from their customers as possible and to hand it to their shareholders.

      Is that really what you want pharmaceuticals research to look like?

      They got to the moon and returned, which was never done, and which was still not done 30 years later by any private company, because there is no profit.

      I want pharmaceuticals research to find cures that have not been found, even if there is no profit.

    6. Re:Patents are theft by Phil-14 · · Score: 1

      But you think it's progress that the government
      went from going to the moon to mounting "expeditions"
      to low earth orbit? That's not progress, that's
      regress. The government also does all it can to
      make sure the price of space launch stays high.
      They manipulate the market, and basically say to
      investors wanting to invest in non-government-design
      bureau launchers (i.e. companies besides LockMart
      and Boeing, which are more like communist design bureaus like Sukhoi than private companies... I take that back, Sukhoi is a lot more like a private company these days) that any reduction is impossible. If that's the way you want healthcare to go, then try not to screw it up for the rest of us.

      --
      (currently testing something about signatures here)
  61. Scrooge on AIDS drugs. . . . by Anonymous Coward · · Score: 0
    Why-is-it wrote. . .

    The issue is that Roche (et.al.) want to charge more for a few doses of drugs than people in third world countries can expect to make in a year.

    Why ?? To quote Scrooge:

    Then let them die, and thus decrease the surplus population. . . .

    Especially as they've now cut into their profits. . .

    1. Re:Scrooge on AIDS drugs. . . . by Bobo+the+Space+Chimp · · Score: 1

      The problem is if they substantially less for Brazil, then richer countries' politicians start beating their chests, saying "Wellll, why should WE get ripped off if Brazil doesn't have to pay very much? Those EVIL DRUG COMPANIES! I will bash the heads of those evil people who cure drugs, for you, The People!"

      And the ignorant crowds cheer.

      And drug companies can't cover research, research is slowed or halted, and over the years, far more people die than would have. But they won't show up on any stats.

      It's a little too sophisticated for The People to understand that millions die because health care technology is stuck at the year 2000, whereas in a parallel universe it's up to 2010, another it's 1994 and a third, 1978.

      Nah, better to save a few lives now and get the brownie points than to save millions later to a hazy concept few understand.

      --
      I am for the complete Trantorization of Earth.
  62. Jurassic Park by xenocide2 · · Score: 1

    I guess Micheal Criton can't be considered an authority on pharmasudicals, but I remember in the book one of the characters mentions that nobody wants to spend time researching things like cancer cures or AIDS cures, precisely because the government will intervene on behalf of the public, limiting your profitablity.

    --
    I Browse at +4 Flamebait

    Open Source Sysadmin

  63. Well that's just how life is by serutan · · Score: 1

    It's the real world, and people do whatever they think they have to do, regardless of the law. Brazil's action is no more wrong than running red lights to get your kid to the hospital. I'd do that, and so would you, so spare us the sermon.

    1. Re:Well that's just how life is by Anonymous Coward · · Score: 0

      I saw someone do that (run a red light) ended up killing three people including the one they were getting ot the hospital.

  64. Uhm, no...this is a BAD thing! by Arethan · · Score: 1

    Think about it this way. If pharmecuticals are no longer profitable to research and develop, guess where all of that mad-cow, cancer, and other live threatening disease research is going to go. If you answered 'right down the fscking tubes!', you were correct!

    If brazil wants to really help themselves, start giving away clean needles and condoms to the public. You can educate the people all you want, but if they are too poor to buy a needle (cuz all their money goes to drugs), or are horny as hell and don't have a rubber on them, people will ignore their knowledge and do whatever they want at the moment. Thus, aids is spread.

    Life is full of choices, and if large groups of people are too stupid to use their brains and protect themselves, then I guess we didn't need them in the gene pool anyways.

  65. Drug Companies Rarely Design the Drugs They Sell by dondelelcaro · · Score: 1

    There seem to be a great many people out there on slashdot who haven't bothered to look up exactly who designed the currently used anti-aids drugs. None of the companies who currently hold patents on them were actually involved in doing the research that generated the drug and demonstrated it's initial efficacy.

    That research was funded at various public (and private) higher learning institutions throughout the world.

    What the drug companies did do is purchase the patents from their current holders and chaparone the drug through FDA approval. Of course, the job of taking a drug through FDA approval is quite arduous and involves a considerable amount of cash, but NONE of that cash is spent in R&D, it's spent on efficacy studies and the ilk. (You might argue that this is a form of R&D, I like to look at it as QA.)

    Of course, an interesting history lesson is to look at the United States point of view towards International Patents in the early part of the industrial revolution, especially regarding textile manufacturing. (Most of the patents for textile weaving were held in GB, and the US basically ignored them.) [Just in case someone thinks that the US has never behaved as brazil has]

    Finally, regarding the search for a cure for HIV. A cure (if one is ever found) will most likely come about rhough basic research being funded already by NIH and other organizations at your local university instead of through targeted research by your local pharmesuitical group. Basic research by CDH and other groups is what gave us the knowledge to use various reverse transcriptase inhibitors, and it's what will bring in (if possible) the cure for AIDS.

    --
    http://www.donarmstrong.com
  66. Good for them. by scott1853 · · Score: 1, Troll

    Nobody is going to be sympathetic to a single company vs. half a million people dying. That's just sick.

    "I'm sorry son, Mommy and Daddy can't keep you alive because Mr. Rich needs a new ivory backscratcher. We just can't expect him to use the same one every day."

    What kind of fucking morons run Roche. Lets evaluate the financial situation here. Brazil is spending 82 million dollars a year on this drug, between production and licensing. That means the licensing part is 32 million dollars. Licensing cost nothing for a company except executive paperwork which they have their underpaid secretaries or interns do for them. This is just greed.

    Sometime before I die I'd really like to see a law passed against excessive greed. A law that states money is not greater than or equal to people or even the rights of people. Maybe if some CEO is living on the streets and he has to rip of somebody else living on the street then that would fall into a gray area. But making many suffer so you can please your elitist friends and shareholders as well as buy yourself a new yacht shouldn't constitute as legal.

    1. Re:Good for them. by Anonymous Coward · · Score: 0

      remember all that money isn't profit, it's debt payment.

    2. Re:Good for them. by SuiteSisterMary · · Score: 2

      Look at it this way; if this were guns, designed to kill people, Roche would be up on profiteering charges. But it's drugs, designed to save people, so instead of being a necessity, it's a luxury. Therefore, charge what you will.

      It's funny because it's true.

      --
      Vintage computer games and RPG books available. Email me if you're interested.
    3. Re:Good for them. by mimbleton · · Score: 1

      "on profiteering charges"

      What the hell is that ?
      Isn't all business about "profiteering" ?

  67. Re:India, Brazil, China... half the planet already by Anonymous Coward · · Score: 0

    This is a wonderfully idealistic view of the world, but woefully out of touch with reality. Operating systems are incredibly expensive to develop. If other developers follow RMS, then you're cutting the financial backing for R&D. Say good-bye to most any hope for a stable, secure OS, and fixes for a good number of other bugs. Sure, government-funded research will continue, but by destroying a software company's R&D budget, you'll be drastically slowing down the rate of technological innovation.

    If developers truly care about fostering technological innovation AND providing support to those who need it, they would subsidize the cost of operating systems. Software companies would be able to recoup their huge R&D investments and lusers would have access to low-cost software. But this would likely require raising taxes... and that's a whole other topic of discussion.

  68. Prendergast??? by woody_jay · · Score: 1

    Did anyone else notice that this is the same name as the detective from the movie "Falling Down" with Michael Douglas and Robert Duvall?

    Seems weird to me.

    --
    Of course, that's just my opinion, I could be wrong.
  69. Look to Argentina by WinPimp2K · · Score: 1
    Who told the pharmaceutical companies that they were going to make the drugs themselves. I think the licensing terms got a whole lot less oneraous all of a sudden. (This was before the same problem hit the courts in South Africa) There were some important points they made in Argentina:
    • Their entire economy system had no chance of dealing with the sheer drain all of the untreated AIDS patients would have put on them. The costs involved in treating AIDS is much less than the simple loss of productivity from having a large population of people with untreated AIDS - plus the infected people remain productive.
    • The drugs require training to be used properly, but they discovered that people are motivated when they understand the alternative is death.
    • The cost - when manufacturing the drugs themselves worked out to about 700 USD per year versus the 10,000 USD per year in the USA. And they were still paying some royalties to the pharmaceutical companies.

    Of course, as has been pointed out, pharmaceutical research is exppensive. I propose that the UN set up a cash reward for a cure. Surely (placing pinky at corner of mouth) ONE HUNDRED BILLION DOLLARS would be a great motivator for the pharmaceutical companies - especially if it were combined with an exemption from liability for any side effects of the cure.
    --

    You either believe in rational thought or you don't
    1. Re:Look to Argentina by Anonymous Coward · · Score: 0

      Where's the $100 billion going to come from, genius?

  70. Fair price ? by DVega · · Score: 1
    "Country refuses to pay a fair price for drugs to save its own people"

    A Fair Price?? Brasil is capable of producing this drug at 40% of the cost. So, he is saving more people. We habe to remember people like Jonas Salk, whose only interest was the public wellfare.

    Edward R. Murrow: Who owns the patent on this vaccine?
    Jonas Salk: Well, the people, I would say. There is no patent. Could you patent the sun?

    --
    MOD THE CHILD UP!
    1. Re:Fair price ? by codeforprofit2 · · Score: 1

      Producing the drug is cheap.

      The research that made it possible is expensive.

    2. Re:Fair price ? by Lemmy+Caution · · Score: 2
      And a lot of people who did the research for failed efforts got no profit at all, even though it freed up the successful researchers to find the right path.

      And most researchers were trained in public school systems, and recieved public grants to do their work, etc.

      My hope is that this leads to the revival of public research. The privitisation of medical researches makes it much, much more profitable to develop "treatments" than cures - it's a lot more profitable to sell someone morphine for life to treat the pain of a broken leg than to just reset the leg.

    3. Re:Fair price ? by fedos · · Score: 1
      The research that made it possible is expensive.

      Of course, it has been shown that drug companies great over exagerate the costs of research, usually includin other unrelated costs when reporting the figures to the government.

    4. Re:Fair price ? by benedict · · Score: 2

      I think Roche will survive, flourish even, despite being unable to suck the blood of Brazilians.

      --
      Ben "You have your mind on computers, it seems."
    5. Re:Fair price ? by benedict · · Score: 2

      Don't forget that in the U.S., drug research is tax-subsidized -- that's right, people, we pay coming *and* going for this stuff -- after we partially pay for the research, Lilly or Pfizer or whoever gets the patent and gets to charge us $100/bottle for 17 years.

      --
      Ben "You have your mind on computers, it seems."
  71. From the article by jayhawk88 · · Score: 1

    Federal officials said they were unsuccessful in talks with Roche to lower the prices the country paid for nelfinavir. Company officials could not be reached for comment.

    Company officials could not be reached for comment, mostly because they didn't feel like answering the question, "Why won't you work with Brazil to sell the rights to produce (not the actual drug mind you, just the rights) nelfinavir at a price they can afford so they can help save the lives of their people?"

  72. No pharmacudical company is an island by SirSlud · · Score: 4, Insightful

    The points regarding that this action will discourage R&D are probably true, to the extent that this move may cause companies to reduce their R&D budgets. But what good is R&D and new drugs and technologies if only x% of the world can take advantage of developments supposedly in the name of 'humanity'?

    There are countries out there that could have many, many, many more people and companies working on the same solutions, thus spreading the R&D costs across more organizations and making information and research sharing more cost effective. Unfortunately, those countries are having a tough time, in various capacities, keeping their population alive, let alone wealthy enough to invest in new companies, research facilities, etc. Of course, neo-liberalism preaches the 'more for me, less for you' mantra, so the existing companies don't really warm to the idea of more 'competition'. If they could have their way, everyone in said countries would buy their drugs, but not get well enough to spur technological development in that country. Poor people are always a companies favorite customer .. no leverage, no money management skills (when you don't have money, you don't learn how to manage it); and less education increases the likelihood that you will repeat the act that caused you to require the product in the first place somewhere down the road.

    For an industry that was caught redhanded not so long ago in an industry-wide price fixing scam (yes, Roche participated), I think they have alot of nerve complaining about losing patent fees in areas where their cure could stop an epidemic of life-threatening deseises, in addition to helping set the stage for opportunities, development, research and growth in the countries that need it.

    --
    "Old man yells at systemd"
    1. Re:No pharmacudical company is an island by Fjord · · Score: 2
      But what good is R&D and new drugs and technologies if only x% of the world can take advantage of developments supposedly in the name of 'humanity'


      What seems to be lost in this thread is the real reason why patents exist. The purpose of the patents are to trade the secret for limited exclusive use. If there were no patents and this company did develop this drug, then they would keep the drug secret, develop obfusticated pills, and continue to only allow that x% access into perpetuity. At least with patents, it convices the companies to give everyone access after the expiry.

      Another thing that has been lost in this thread is the difference between the typical /. patents we object to and this patent. I don't object to software patents like, say, RSA (which has now expired and everyone may use the technique), which would not naturally be derived by an average person with cryptography skills. Before RSA, if I were to say to a person "build me an algorithm for asymmetric key encryption" it is doubtful that someone would come up with RSA.

      But I do object to "One-click shopping" because it basically patents a requirement. If you ask an average person skilled in dynamic web design to build a "one-click" system, they are going to use a database, and likely similar technologies that are covered by the one-click patent. It isn't innovative. It's trivial. Even

      Similarily, if someone were to say to an average skilled biochemist, "make a drug that increases survival of AIDS patients," it isn't likely that said person would come up with this drug (or anything at all). I would object to a patent on all "pills or capsule taken orally that increase survival of AIDS patients" because that would be patenting a requirement.

      --
      -no broken link
    2. Re:No pharmacudical company is an island by SirSlud · · Score: 2

      I know why patents exist. At the risk of sounding like some uppity ivy leaguer (of which I'm probably the opposite), my father owns few patents; we have arguments about the system, and what role the US patent system plays in the development of the race and whatnot.

      I'm not objecting to patents, nor am I suggesting that every person in the world should be able to break patent ownership at whim. I'm aware that patents are seemingly neccessary because it does encourage the sharing of technology and invention, and discourages (to some extent) the hoarding of the discovery.

      BUT ....

      Patents exist, other than the reason above, primarily to provide the 'inherent right' (and I use quotes, because I dont think it's a right) of ownership to an inventor. But a nasty side effect is that there is very very little motivation to invent something that helps those with nothing to offer back (ie, those in need). I feel the PRIMARY role of technology and innovation should be to help thy common human, not to fuel the economy and dangle the carrot in front of the inventors nose. Reward seems to be the only reason anyone should do anything for anyone else, according to neo-liberalists. Capitalism is the system that keeps this mentality in place. Reward is important and neccessary, but should not be the end and be all of motivation. So, what motivation is there to invent something which helps those who can't afford it? Just imagine the millions and millions of inventions out there, waiting to be invented, for lack of a 'consumer base' to repay for the invention. Ironically, these are the inventions that really /would/ improve the quality of life on earth, not the quality of 10% of it's inhabitants' driveways, SUVs, and internet functionalities.

      Nevermind that "an assymetric key encryption algorithm" may have many implementations, while, when it comes to medicine, there /may/ only be one (or likely, at least significantly fewer that accomplish the required task). So I don't think you can just compare invention in completetly seperate fields, and put them under the same umbrella with respect to patents (another thing I believe should be changed).

      I guess what I'm saying is that, if some parts of the world can't afford to play by the 'rules', they wouldn't have been part of the planned consumer base for the investors in the first place. So there should be no 'loss' to the inventor, since they shouldn't have counted said people as possible customers in the business plan stage. This is even more relevant in the situation where the wealth of a population largely depends on its health and how badly external forces are attempting to suck it dry .. doesn't a healthy and more wealthy country that wouldn't have bought product Y in the first place make them a whole new potential market for product X; a market that may not have existed had you not licenced the use of the dicovery behind product Y for free?

      Anyhow, it's a nice, big, totally contexual argument, one that has no obvious solution, but our current blanket approach to global markets and innovation belies the reality that this is a huge planet, with different people, societies, needs, geography, customs, values .. if you want to provide access to your ideas, you should be subjecting yourself to these conditions and possibilities. A world where less is invented, but no one suffers for lack of payment is a far superior world to that which plays class and market favorits with life saving technologies that exist, in my opinion. People will always suffer - I just think it's cruel that people have to suffer knowing there is something out there that could help them had they been born into a situation where they would have a hope of affording it. Maybe thats what it boils down to.

      Incidentally, I also think that more innovation would take place in a world where the inventor is owed nothing .. primarily because more people would piece together new solutions from other new inventions far quicker, outweighing the downside of lack of reward to potential inventors. Also, the inventor would never not get ANY reward ... surely the inventor would have an inside track on marketing the implementations, making improvements, etc. They would be able to position themselves as the 'expert' .. I refuse to accept that finacial reward would not happen in a world where the inventor was not given the right to patent fees. (Of course, you'd have to make sure that the 'public credit' for ideas wasn't being stolen from the true inventor, but that certainly can't be any more complicated than the current patent filing process .. ) I realize, however, that that's a personal opinion that is difficult to substantiate.

      Okay, that was one big mess, but I hope you can glean some level of logic behind it.

      --
      "Old man yells at systemd"
  73. This isn't about LIVES, it's about MONEY. by Anonymous Coward · · Score: 0

    I would like to point out to all the people saying "Way to go Brazil for respecting lives more than money!" and "This is great when people put individuals before money!" and so on that this is actually about Brazil wanting to cash in.

    Do you really think Brazil is doing this to save lives? Heck no! They just want to reduce spending. It's almost always about the $$$$. It's that simple, but "saving lives" is a great pretext to ripping off the patent holder.

    Really, this decision by the Brazilian Government is damaging to the drug industry and other similar industries because they spend millions on research and development to create unique solutions to problems with the goal to sell that solution to those who want or need it.

    Take away the incentive and you take away the motivation to create things like this in the first place. Of course, they will still make a killing with or without Brazil but the principle still holds.

    "I had the cure for cancer but they wanted me to release in under the GPL so I burned it."

  74. this kind of trend by zeus_tfc · · Score: 1

    At the risk of being flamed, mod-ed down, and admittedly not having read the article, I think that this kind of trend may not be in our best interests. Patent laws don't just protect large corperations, they also protect ordinary people from large corporations. I know that the majority of people here think "intellectual property" is a joke, but when you start down that path, where will it lead you? Where does it end? Are all inventions now public domain? In this kind of atmosphere the "little guy" will get trampled. Imagine some "nobody" tinkering in his garage comes up with a new idea, a valuable idea. Without patent laws, any corp can snag the idea and make a mint because of production capacity and marketing, and the nobody stays a nobody.

    At this point you say, "but we're not talking about inventions, we're talking about IP!" Where do you draw the line? Where do you make the distiction? A pharmaceutical company spends millions in research to come up with the correct combinations of chemicals that do exactly the right thing. How is this different that comming up with the right combinations of levers or parts to perform an operation or task?

    Now you say, "But this is a treatment for a disease! Lives hang in the balance!" Again I say Where do you draw the line? It may not be as big a step as you might think from: Our people are dying, to: Our people don't have the quality of living that yours do.

    Please don't get me wrong, I don't really sypathize with the swiss pharmaceutical company, or pharmaceutical companies in general. My problem is with this idea that nothing belongs to an individual or group. Yes I think things should be shared, but until we come up with a reasonable and concise way of determining how or when things should be co-oped "for the greater good," I don't think we should to it.

    Then again when has my opinion mattered? Trick question: Never!

    Zeus_tfc
    Outside of a dog, a man's best friend is a book. Inside of a dog its too dark to read. Grouch Marx

    --
    "...At the end of the day"..."when everyone goes home, you're stuck with yourself." RIP Layne Staley
  75. ALL the history. by Trinidad_T_Tobago · · Score: 1

    Here from Brail, I must say that the government
    tried to talk with Roche.
    Roche said no no no.
    So, they are NOT trying to destroy the pharmaceutical
    industry, nor Roche, not kicking tha patents away.
    They tried to negociate a lower price, respecting
    all the legal procedures, but Roche , with all it's
    power, repelled the terms.
    They wanna $$$ , fsck the people.
    So Brazil take this action...

    Whadda ya make on this shoes?

  76. Re:Bullshit- no... by Anonymous Coward · · Score: 0

    You even notice that some cultures are so decadent that you wonder how they will survive? If they cannot learn from their mistakes, why should we hold their hands. If the AIDS epidimic ever ended up infecting and killing some signifigant minority. You can bet your ass the rest of the population would start saying "gee maybe we should keep our pants on". Sorry but if its minoritys and the uneducated who keep getting and then spreading these diseases, thats too bad. Maybe there is a deeper meaning there. Its really not too hard to think "gee if I don't screw this person, I may not get AIDS".

    Here is an interesting question, whats going to happen when say 30 or 40 % of a population is going to be infected? Will there be wars between those infected and those not?

  77. Who's Going to Pay? by asdfasdfasdfasdf · · Score: 1

    YOU ARE. That's right, as the cost of Drugs in the US goes up, so does your insurance & deductables.. You are personally paying the world's social welfare. I hope you enjoy it...

    So go on, yahoos, cheer the Brazillian Government, "Stick it to the Man! Yeah!" You've earned it. (Well, you're paying for it, anyway)

    One more thing: How about this scenerio? The drug companies decide to stop production on a cure for AIDS. Why bother? If 95% of the infected people in the world live in countires that won't pay for it, why would they continue to research a cure? As the free "management" drugs become available, MORE people will get AIDS in these countries, because MORE people will be living longer, and therefore fucking and shooting up longer... with no cure in sight.

    1. Re:Who's Going to Pay? by Bonker · · Score: 2

      YOU ARE. That's right, as the cost of Drugs in the US goes up, so does your insurance & deductables.. You are personally paying the world's social welfare. I hope you enjoy it...

      Money is of no importance. Only life is important.

      If have to pay $10 more a month in insurance, so be it. If I have to pay $10 more a month in taxes, well , Americans all got a tax refund that many more than half of us voted against.

      --
      The next Slashdot story will be ready soon, but subscribers can beat the rush and slashdot the links early!
    2. Re:Who's Going to Pay? by Anonymous Coward · · Score: 0

      Did you return your tax refund? After all it wasn't YOUR money, it's the government's money right?

      If money is of no importance, why are people like you so eager to take it from everyone and give it to that model of frugality, the government?

      By the way, more than half of us voted against Bill Clinton BOTH times (he won with 42% and 48%). Let's repeal everything he ever passed as being invalid too.

  78. Will it help or hurt by 0tim0 · · Score: 1
    This may sound silly, at first, but I wonder if giving these drugs will help save some people or kill more in the long run.

    The thing that makes AIDS such a devastating disease is that it takes too long to kill. So it has time to spread much farther. So extending the lives of people with AIDS without serious changes to their behavior will mean that more people will be infected. I don't know what the real impact will be, but I am curious.

    On a side note, I do think drugs should be patentable. It's the only way to motivate real reasearch on a drug. But is anyone else bothered by the fact that a drug company will make more money by treating a disease like AIDS than curing it. I mean if one of these companies came up with a cure right now, their collective stock prices would drop like a rock: they would lose a steady stream of revenue for a short-term pop.

    Kinda the same reason microsoft wants subscription based software ;)

    --tim

  79. You call that a troll? by fmaxwell · · Score: 2
    If you are going to troll, at least don't be so obvious about it. Don't post something that is so clearly concocted to enrage. No one is really going to believe that you are so ignorant that:

    you judge people's worth based on their sexual preference.

    you believe that only gay people get AIDS.


    You need to try subtlety. Claim that the stockholders of the drug company are being cheated or that we should stop trading with any country that violates a U.S. patent. You are dealing with a sharper bunch on here than you realize and no one here is going to believe that you are that stupid, bigoted, and narrow-minded. Try again.

    1. Re:You call that a troll? by CmdrTaco+on · · Score: 0
      You're mostly right, but I do judge people's worth on their sexual prefrence. Gay people not propegate the human species. Therefore they are as useless as Microsoft Bob.

      Also, are you implying that the stockholders of these drug companies aren't being cheated? And that we should trade with countries that violate our patent laws? Heh, good one.

      --

      saru mo ki kara ochiru

    2. Re:You call that a troll? by Bobo+the+Space+Chimp · · Score: 1

      > Gay people not propegate the human species.
      > Therefore they are as useless as Microsoft Bob.

      Technically true, but 99% of sex is not intended to propagate the species. Intelligent, free, consenting adult humans can elect to engage in non-propagatory activities. We do not create governments to regulate such things.

      --
      I am for the complete Trantorization of Earth.
    3. Re:You call that a troll? by fmaxwell · · Score: 2
      You're mostly right, but I do judge people's worth on their sexual prefrence. Gay people not propegate the human species. Therefore they are as useless as Microsoft Bob.


      Do you really believe that the only thing that anyone, including you, can contribute to humanity is more people? Albert Einstein never had kids. Mother Theresa never had children. Does that mean that their lives were complete wastes and that they were "as useless as Microsoft Bob"? Do you also feel that infertile couples have nothing to contribute? Does that mean that welfare mothers with 14 kids are making a wonderful contribution to society?


      Here's a clue: We don't need any more people. We have more than enough already. The best thing that could happen to insure the survival of the human species is fewer people polluting the planet and using up its resources.

    4. Re:You call that a troll? by mimbleton · · Score: 1

      Well, gays contributed AIDS as it was first recorded among them.
      And please do not bullshit here about lack of relation between gay lifestiles and much greater rates of AIDS among them.

    5. Re:You call that a troll? by CmdrTaco+on · · Score: 0
      Humans are animals. We live as a species to bump other species out of existance and rule the planet and eventually the universe.Life is a force that we can not deny and don't bind your morals to the concept. Einstien SHOULD have had kids. if you have super genes you are selfish if you don't share them. The sooner we get to the other plane the better. the plane where we recognise we are not individual life forms, but part of a greater being, a being called human kind. We will infest this little galaxy and move onto others. If we don't first all these other alien species will, and you think they'll have any need for a competing species? ha! This is a life and death matter. Maybe your feeble little mind doesn't grasp the idea, or maybe you just don't want to admit it. Like many others wrapped up in the pathetic details of life, you fail to recognise the greater plan. People like you will be left behind while the shrewd, and wider scoped people will live on to live in infamy.

      I'm a big picture man. You tend to look at the little picture etched on the head of a pin. make sure you don't poke yourself in the eye.

      --

      saru mo ki kara ochiru

    6. Re:You call that a troll? by fmaxwell · · Score: 2
      Well, gays contributed AIDS as it was first recorded among them.
      And please do not bullshit here about lack of relation between gay lifestiles and much greater rates of AIDS among them.


      I did not say that there was no relationship, but gays are not the only people that ever got AIDS. Blaming gay people for AIDS is like blaming black people for sickle cell anemia. They are the victims, just as have been a tremendous number of hemophiliacs, IV drug users, and even people like Magic Johnson.

    7. Re:You call that a troll? by fmaxwell · · Score: 2
      Humans are animals. We live as a species to bump other species out of existance and rule the planet and eventually the universe.


      So you feel that overpopulation is the key to the survival of the human race. That will work real well -- at least until we run out of food.


      Maybe your feeble little mind doesn't grasp the idea


      "Feeble little mind"? That can't be the explanation -- and I have the IQ tests to prove it. So I'll go back to my original premise: You are just a troll. Happy trolling.

    8. Re:You call that a troll? by mimbleton · · Score: 1

      "They are the victims, just as have been a tremendous number of hemophiliacs"

      Hell no.
      They are the victims by their own choice.
      A huge difference if you ask me.

    9. Re:You call that a troll? by CmdrTaco+on · · Score: 0
      So you feel that overpopulation is the key to the survival of the human race. That will work real well -- at least until we run out of food.

      You have yet to refute my point. There is no such thing as over population when you talk about the survival of a species. If we're not off this planet or developed a sustainable food supply by the time the Earth get over populated with humans, then we deserve to die off. Or we'll end up eating each other.

      "Feeble little mind"? That can't be the explanation -- and I have the IQ tests to prove it. So I'll go back to my original premise: You are just a troll. Happy trolling.

      You are so diluted if you actually think IQ has anything to do with survival. IQ is a human test of irrelevant knowledge, that is useless outside the cocktail party atmosphere. The dinosaurs conquered this planet for hundreds of millions of years (humans have been around for what? 100,000 at the most?) and they didn't even have a way to test their IQ. If an asteroid or comet (which also has no IQ ) hadn't wiped out their empire, humans (mammals) would never have taken over the planet. So I spit on your IQ test scores (as if they proved anything to begin with. All they prove is that you put too much faith in IQ tests). I can picture you at a job interview:
      Employer: Well you have no useful skills or experience. And you're a bit of an ass. Why should I hire you?
      fmaxwell: Well if you take a look at my IQ scores at the bottom of my resume, you'll plainly see why you'd be an imbecil if you failed to hire me <grin>
      Employer: Do you mind standing up and bending over. My shoe needs polishing and you have shiny pants.
      fmaxwell: I'm glad you see it my way! (bending over)

      BOOT!!!!!! out on yer arse!

      --

      saru mo ki kara ochiru

    10. Re:You call that a troll? by fmaxwell · · Score: 2
      They are the victims by their own choice.


      Choice? You think that each gay person simply decided that they wanted to be sexually aroused by members of the same sex, that they wanted to be the victims of hate crimes, gay bashing, and prejudice?


      I could not simply wake up one morning and think to myself "I think I'll be gay from now on." Could you really just flip a switch inside your head and change which gender was sexually attractive to you? No offense intended, but that's really weird that you can do that. Most people are "hard-wired", as to whether they are straight or gay.

    11. Re:You call that a troll? by mimbleton · · Score: 1

      No, it is a choice of having unprotected sex with great number of partners which gays are famous for.

    12. Re:You call that a troll? by Anonymous Coward · · Score: 0
      Hell no.

      They are the victims by their own choice.
      A huge difference if you ask me.

      I'll keep that in mind next time I need to ask someone knowledgable about something. Trust me, it won't be you.

    13. Re:You call that a troll? by fmaxwell · · Score: 2
      No, it is a choice of having unprotected sex with great number of partners which gays are famous for.


      Wilt Chamberlain, Magic Johnson, and many other straight people have boasted of their sexual conquests, most of which involved uprotected sex. It's not just gay people that do that.


      You paint with an overly broad brush. Most gay men no longer have unprotected sex. Many gay men who contracted AIDS when the epidemic started had no idea of how the disease was spread, from whom they got it, etc. It was a complete mystery to epidemiologists as well as to the gay community. Prior to AIDS, there was little reason for gay men to need "protection" when they had sex. It was not like either person would end up pregnant. Even now, condoms, while helpful, are not 100% effective in stopping the spread of AIDS. Sometimes they tear. Sometimes the come off.


      You need to chill out on the gay bashing. There are adults here and we don't feel threatened by someone else's sexuality.

    14. Re:You call that a troll? by mimbleton · · Score: 1

      "You need to chill out on the gay bashing. "

      The only reason I engaged in this discussion is because couple of weeks ago I read an article in Chicago Tribune describing alarming growth of AIDS cases among gays ( specially Black gays.)
      The author attributed this to complete stonewalling from gay organization which are busy fighting any attempt by link AIDS with gay lifestyle.
      Basically, these people were claiming that gays lifestyle does not bring greater risk of AIDS infection.
      Personally, I have nothing against gays as long as they do not impose their sexual preferences on me.

    15. Re:You call that a troll? by fmaxwell · · Score: 2
      The author attributed this to complete stonewalling from gay organization which are busy fighting any attempt by link AIDS with gay lifestyle.


      The unfortunate fact is that AIDS does not get enough research dollars and public awareness if it is viewed as a "gay problem." If mom and dad think that their precious, (assumed) straight son or daughter might become infected then they will start demanding that something be done. That's why groups representing the gay population are fighting so hard to prevent AIDS from being closely linked with a gay lifestyle.


      I am also sure that straight AIDS victims have no desire to have their coworkers, friends, and family to assume that they must have contracted the disease through gay sex. Basically, it doesn't serve anyone's best interests to have the disease be seen as a problem only for the gay community.

    16. Re:You call that a troll? by Anonymous Coward · · Score: 0
      Most gay men no longer have unprotected sex.

      But for how long? Trends have been going back up at a high rate in the incidence of unprotected sex in the gay community, which for lack of a better phrase was scared 'straight' there for while.
    17. Re:You call that a troll? by fmaxwell · · Score: 2
      But for how long? Trends have been going back up at a high rate in the incidence of unprotected sex in the gay community, which for lack of a better phrase was scared 'straight' there for while.


      That's one danger with drugs that control the disease in so many victims. More often than not, people with AIDS now look perfectly healthy. There are now young adults that were in grade school when the AIDS epidemic was really hitting hard. They didn't see close friends get horribly sick and die. They know that AIDS is still out there, but they don't really see it as a real threat to them. Some even view it as an inconvenience that can be controlled with drugs -- like herpes.


      Part of the problem is the lack of sex education in schools. It's time to stop pandering to the religious right and start teaching kids things that they need to know in order to avoid becoming victims of STDs, regardless of whether they engage in vaginal, oral, or anal sex. The importance of condom use should be taught and to hell with the Catholic church. There are people dying.

    18. Re:You call that a troll? by ttyRazor · · Score: 1

      Unfortunately the stupid traits are also the ones that do the most to encourage reproduction. Or, perhaps they are better referred to as "distracting" traits. "stupid" people are probably just too preoccupied with doing stuff that leads to children instead of irrelevant smartypants stuff that improves the human condition. As a lame example look at that show Earth:final Conflict. Basically the aliens became so preoccupied by the smartypants stuff that they lost all their will to procreate, and eventually atrophied into sterility.

      People like Einstein, as desireable as they are in the gene pool, are an abberation where too much of their intelligence is diverted away from the social interaction neccesary to hook up and breed. It's ultimately not selfishness but a lack of traits that allow reproduction to take place. I can only imagine how sperm donorship, contraceptives and infertility treatments are going to distort our gene pool where the most active fuckers aren't having children and the least capable are.

      And don't forget that some of the worst stuff in history was perpetrated because those descended from those with super genes were given the respect and authority of their fathers, when only the defective genes were carried over.

  80. GPL on drugs research by jagripino · · Score: 1

    "Did the company base their drug on any previous works done by public organizations?"

    Good point. To counteract this, academic researchers could GPL their research work, so that any drug based on that "code" has to have an open source.

    How about it? Or am I just stupid?

    1. Re:GPL on drugs research by Anonymous Coward · · Score: 0

      Yes, you are just stupid.

      Go to cuba, northern korea and see how much innovation and progress are beeing made in a "share economy".

    2. Re:GPL on drugs research by Anonymous Coward · · Score: 0

      What, Cuba? You mean that little Communist Island that developed a vaccine against a Meningitis strain?

      Oh yeah, no progress there!

  81. sounds familiar by Anonymous Coward · · Score: 0

    ...that public needs justify the disregard of patent protection.
    From each, according to his means, to each, according to his needs.
    So, to hell with the drug company which spent an incredible amount of money discovering the drug, huh? That certainly provides an incentive for them to invest billions to discover the next treatment, doesn it?

    Damned socialist morons -- you'll never get it, will you? When one cannot reap the rewards of one's work, the effort will not be invested. Proof? All those wonderful, life-saving treatments coming from China, Russian, Lybia, Cuba, Korea, etc.

    -- Spaz!

  82. Re:India, Brazil, China... half the planet already by AsylumWraith · · Score: 1

    Uhm, but should countries (and by that, I mean their peoples, cause everyone knows countries get their money fromf the people) also foot the bill for the huge advertising campaigns waged by the pharmaceutical companies? And trust me, that's probably why Brazil couldn't afford the price.

    I dunno about you, but I don't need to see those incomprehensible ads for Viagra or Paxel. If I need the stuff, my doctor will prescribe it to me, and explain it, without showing me a tape of a commercial.

    Just my $0.02

  83. Re:Oops!! Prendergast??? by woody_jay · · Score: 1

    Sorry guys, I accidently posted this to the wrong article.

    --
    Of course, that's just my opinion, I could be wrong.
  84. Funny contridiction by Anonymous Coward · · Score: 0

    "Human life is sacred and every life is worth more than all of the money in the world."

    Funny how when it comes to the possibility of getting a fatal disease and causing DEATH, that could so easily be prevented, people seem to ignore this issue. Hoever when it comes to handholding people who had no respect for their own bodies, this kind of statement is always made.

  85. public good be damned, I will have no part of it by Richthofen80 · · Score: 1

    public needs justify the disregard of patent protection
    Yep, that's fine, as long as the "public" is you, and not someone else. Basically, our pressure group warfare type of lobbying efforts in the United States consists of people fighting over the right to say they are the public.
    This is a sham. Brazil's government, or it's scientists, could never have invented these drugs. they're stealing the ideas. They're shortcutting the natural process of development. They want results, they don't want to work for them.
    If I ever hear that "public needs" crap again, it will probably be about how the public needs my money, and somehow I'm not the public...

    --
    Reason, free market capitalism, and individualism
  86. What if this was China by Anonymous Coward · · Score: 0

    Drug companies need to learn where they should be profitable. 3rd world countries and Brazil are not it.

    Western Europe and North America are where the revenues come from. I think some compassion with Africa is needed, after all it is the West that really fucked things up for them in the first place.

    Now for a country like China, no way in hell. They want to be a super-power, that means taking care of your own.

    Drug companies have seen patent durations increased, have seen profits soar, and get government funding. So how about this. Enforce the patents, but shorten them back to 5 years.

    Otherwise just like the RIAA MPAA, and all the other AAs, you brought this on yourself, so go fuck yourself.

    Good job Brazil, but if China pulls this shit, there should be consequences. I ain't bitter that China bought the Olympics, actually hell I am, being from Toronto, we could have done a much better job.

  87. Re:Bullshit- no... by Jedi+Alec · · Score: 1

    Here is an interesting question, whats going to happen when say 30 or 40 % of a population is going to be infected?

    Let's count shall we? We have epidemics on our hands in:
    - Large parts of Africa.
    - Russia and it's former Soviet Union partners.
    - Almost all densely populated areas in Southern America.
    - Many Countries in Asia.

    In conclusion, within now and 10 years, in all parts of the world except Western Europe and the USA people will start dropping like flies. The only reason people aren't panicking yet, aside from the ignorance common among most individuals, is that HIV has a very long incubation time, which varies wildly among different people, which explains why we don't have piles of corpses around us yet, but someday we will...
    --

    People replying to my sig annoy me. That's why I change it all the time.
  88. Comment removed by account_deleted · · Score: 2

    Comment removed based on user account deletion

  89. Brazil will PAY THE PATENT by Anonymous Coward · · Score: 0

    Yes. The Brazilian Government WILL PAY FOR THE PATENT to Roche, and will produce the drug for cost reduction instead of buying from Roche.

    1. Re:Brazil will PAY THE PATENT by Chris+Hind · · Score: 1

      Not true. Read the article before posting, lamer.

      --
      nal 11
    2. Re:Brazil will PAY THE PATENT by Anonymous Coward · · Score: 0

      You dont belive me, right. Read this artice (use babel fish):

      http://www.uol.com.br/folha/ciencia/ult306u4664. sh tml

      From the artice:


      "O ministro afirmou que está havendo abuso de preço por parte do laboratório e disse que o governo brasileiro pagará royalties (taxa pelo uso da patente do produto) à Roche. "Não somos contra patente, mas contra abuso."


      Translated using Babel Fish:


      "The minister affirmed that he is having abuse of price on the part of the laboratory and said that the Brazilian government will pay royalties (tax for the use of the patent of the product) to the Roche. " we are not against patent, but against abuse."

    3. Re:Brazil will PAY THE PATENT by Anonymous Coward · · Score: 0

      MAN!!
      BabelFish finally reached a 95% perfect translation! heheh
      Ok, it's a 3 line text, but.. it's a beginning.

  90. Only one worry.. by tcc · · Score: 2

    The next big thing(tm) might not have the same amount of effort or ressources ported to it if there's a precedent of patent smashing...

    SOME are public funded, but not all... and I doubt that the majority of the top minds in this world are working in a public funded environment, I am not saying there's none, but surely not a majority.

    --
    --- Metamoderating abusive downgraders since my 300th post.
    1. Re: Only one worry.. by proton · · Score: 1


      If less tax dollars are spent on patent license fees and medicine subsidies (read==overpriced drugs), more tax dollars can be spent on research.

      Research done in a public institution is preferred over corporate ditto, I would dare say. Atleast thats how it works here (in Sweden, a truly Free country unlike the US of A).

      I wish Brazil and their citizens the best of luck and I hope they all get better soon.

  91. Here's another opinion - you're nuts by DG · · Score: 3, Interesting

    OK, so the subject line is a little inflammitory, and thus, by actually stating an opinion, I too am moderator-bait. We share that much at least. ;)

    But as for your opinion itself... can you actually be serious?

    You've got a country full of dying people. There's a drug available that can save a goodly number of them. It's expensive, and you're poor. You have the ability to reverse-engineer the drug (or just steal the formula outright, whatever) and produce it yourself for minimal cost.

    Would you, as the leader of this country, REALLY allow people to DIE a slow, lingering, and very painful death just because a piece of paper says you have too?

    I'm sorry, not me. As a hypothetical Brazillian leader, my duty is to serve the people of my country, not some foreign drug company. If they won't play ball on price, then we do what we gotta do to save them.

    The point on education is a salient one, but this is not a zero-sum game - producing the drug does not mean a reduction in education, nor does increasing education do a dammned thing for those already infected.

    This case is one of the best examples for the "IP is bogus, information wants to be free" position that I've seen. We're not talking about music files or games here, this is information that will actually SAVE REAL HUMAN LIVES, that a corporation wants hidden and protected SO IT CAN MAKE MONEY.

    If that doesn't make you sick to your stomach, I don't know what will.

    This is my real issue with the Libertarians of the world. There is no place in their world-view for the public project, done for the benefit of mankind. Everything must have a profit motive, and protecting profits has priority over all else.

    Just like Marxist-Leninism goes too far, by wanting _everything_ state-owned and state-run, Libertarian goes too far by giving all control to the private sector. Either extreme is insane. The Real World requires compromise, and I for one am glad to see Brazil stick up for REAL freedom, and do what is right.

    --
    Want to learn about race cars? Read my Book
    1. Re:Here's another opinion - you're nuts by KingJawa · · Score: 1

      Write a check to an International AIDS foundation. It's much more effective than claiming that Brazil is not only in the right, but that what they are doing is good.

      What truly ills stomachs is when a short-sighted "solution" -- in this case, theft -- is justified for saving lives. But it does not save lives; it merely trades some lives for many others. If Brazil were to have an epidemic that American companies were already researching a cure for (let's say, West Nile virus or something), would American companies sink an extra dime into R&D? Not anymore. And you cannot violate that drug's patent, for the drug does not exist.

      But, if all the "SAVE REAL HUMAN LIVES" > "SO IT CAN MAKE MONEY" people out there decided that, instead of pricing people out of live-saving drungs, donated some cash or time to AIDS organizations, both conditions would be met: Lives would be saved and R&D would continue.

      No, we can't do everything; as it is, my status on the unemployed line means I only have time to volunteer. But to claim that some pharmacist with three kids and a dog or a lab technician with two elderly parents are less important than an AIDS patient in Brazil is a claim none of us can make.

      If you want to make a difference, stop complaining. Stop spending other people's money. Stop making decisions for others. Do what you can within your means, and the world we be a better place. But go beyond that, and you are no longer doing good.

    2. Re:Here's another opinion - you're nuts by shawnseat · · Score: 1

      Realistically, you can have it only one way or the other. I personally would favor the US Government purchasing the US drug companies and then going to a no-patent system. Unfortunately, a major side effect of this is that know-nothing professional critics of the Government would constantly harp on failures (most drugs never reach FDA Phase I, although from some of the writing so far I suspect a lot of Slashdrones don't know that). Then, inevitably (because most USians -- I am one BTW -- are dolts of the first order), blowhard politicians would do slash-and-burn cuts to a nationalized drug production agency.

      --
      Religion is the opiate of the masses. The wealthy smoke the real stuff.
    3. Re:Here's another opinion - you're nuts by jafac · · Score: 2

      Here's how I would have written the TV Series; Crusader (sequel/spin-off to Babylon 5):

      Crusader finds the cure to the alien plague in first 5 episodes, brings it back to Earth, EarthGov hands it over to the Pharma corps, who patent and license the manufacturing process (remember, it's got to be distributed to every man woman and child on the planet before the quarrantine can be broken) - and they see it as an opportunity to profit, and play hardball on fees.
      The cure they devise is not a cure but an ongoing treatment. The actual cure is given only to corporate officers, board members, and shareholders.

      After an extended period of negotiations, protests, etc. with the Pharma corps essentially holding all the cards, EarthGov attempts to infiltrate the pharma corps to steal the manufacturing process, and fails. Most of the telepaths from the defunct psi corps now work for the pharmaceutical companies. They cut their power, pharma corps are on backup - they are totally self-reliant. There is now a social elite who have been cured, and the rest are sick and dying. Shareholders are not concerned. They know their rights and they want their money dammit (and they're cured anyway, right?)

      Due to EarthGov's noncompliance with interstellar law, their membership in the alliance is revoked. Earth is blockaded as economic sanctions take hold. Only pharma corp ships are allowed free passage.

      As the population begins to die off, after repeated attempts to duplicate the drug or steal the process fail - after even appealing to alien races to manufacture the drug, Earth Gov sends in commandos to take over the pharma corp factories. Pharma corp security forces defend their turf - the Earth Gov forces are mostly sick with the virus. Earth Gov is forced to turn the planetary defense systems on the pharma corp forces as a form of support. Orbital particle beam weapons are taken out by pharma corp mercenaries. Most of Earth's population is beyond hope of treatment by this point, riots, starvation, etc.

      Cured shareholders and corporate executives flee Earth, and are allowed to take up residence on Mars, being proven "virus free".

      I guess that's why I can't find a job as a screenwriter.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
  92. Eminent domain for IP by kiick · · Score: 1

    I've always wondered if the principle of
    eminent domain can apply to intellectual property...
    If the government can force the sale of private property, if it is in the public interest, can the government force a patent to be void for the same
    reason?

  93. Who needs compassion? by why-is-it · · Score: 2

    in the long run, education will save a lot more people than this drug.

    But instead of educating and changing killer lifestyle habits, their government steals IP. This world is going to shit.


    So screw the people who are already infected. They are going to die anyways (they cannot afford the treatment), and will not be able to afford the cure when one becomes available. By all means let us work to protect the rights of the shareholders. Who cares about some poor people who live in some third-world nation anyways.

    Geez, some people think that simply because they are human, they have some inherent rights and deserve to be treated with respect and dignity.

    I suspect that if you were living in those slums in Brazil, you might have a slightly different opinion...

    --
    *** Where are we going? And what's with this handbasket?
    1. Re:Who needs compassion? by Anonymous Coward · · Score: 0

      Why couldn't they just not fuck like rabbits in the first place?

  94. Link to PDF about what this drug is/does by Shivetya · · Score: 3, Informative

    http://www.viracept.com/3_DOSING/AGVR.pdf

    Its pretty complex, but tell me why Brazil or anyone else should have to pay at least something for developing this, let alone testing it?

    --
    * Winners compare their achievements to their goals, losers compare theirs to that of others.
  95. get more of what you pay for by gregrph · · Score: 1

    brazil's efforts to treat all aids patients for free seems to be creating a subsidizing effect for the virus. according to the article 540,000 people in brazil have the aids virus. i wonder how that compares to other countries especially as a percentage of population? i guess you really can subsidize your way out of existence.

  96. Re:You can't stop by Gzusfreak · · Score: 1

    I don't know exactly what version of the Bible ou have been reading, but it is clearly not taken from the same writings that mine was. My Bible, in the Old Testiment, shows me a God who loved his people. He gave them a set of rules to live by called "Laws". These "Laws" were put into place to give a guideline as to how to improve your relationship with God and your fellow man. But, these laws were not obeyed, so they were punished by God.

    The New Testiment shows a loving and forgiving God. A god who loved us so much, he send his son Jesus to die on the cross so that he may be resurected and our sins may be forgiven. God's own son tells us in

    John 13:34 "A new command I give you: Love one another. As I have loved you, so you must love one another."

    1 John 4:7 "Let us love one another, for love comes from God. Everyone who loves has been born of God and knows God."

    1 John 4:12 "If we love on another, God lives in us and his love is made complete in us."

    So, I want you to tell me. With a God that wants us to love one another so much, do you really believe that he would send a plague like Aids? My answer is no, because when Jesus returns to Earth, we will all be judged and held accountable for the things in our lives. Those who are with Jesus at the time of his comeing will be forgiven and saved. Those who are not, I'm sorry to say, will not be so lucky.

    So AC, Which side will you choose to be on.

    (BTW: So that I don't get completely off topic, I think it was a great desicion. I say get rid of all drug patents. It's crazy... profits or lives, which would you choose?)

  97. Bullshit by Anonymous Coward · · Score: 0

    Intentional infection is VERY small part of the HIV problem, probably not even 1%, and thus, it would really not help at all.

  98. You forgot: "There's no such thing... by John+Guilt · · Score: 1

    ...as a free lunch." That's why you had to invent computers, the Internet, the English language, and the capacity for rational though all by yourself before you made that post. Brazil's scientists could never have created these drugs because they're brown, I guess....and its government couldn't have helped because no government has ever done anything good for anyone ever. The "natural process of development" was instituted by God at Valley Forge.

    1. Re:You forgot: "There's no such thing... by Richthofen80 · · Score: 1
      No, what I forgot was "there is no action forbidden to an individual but permitted to a mob"

      Troll. What was with the "brown" comment? because I'm against Brazil's actions here, I am against the race of it's citizens? Don't assume I'm a racist. That's just plain unfair.

      I didn't invent a computer , the internet, or the language. But I did have to pay for a computer, I pay for internet access (unless you live in Houston), and I think that the English language is probably free by now.

      --
      Reason, free market capitalism, and individualism
    2. Re:You forgot: "There's no such thing... by John+Guilt · · Score: 1

      You claimed that Brazil's scientists "couldn't" develop the drugs.

      I was a little loathe to imply racism, but you didn't provide a reason why not. The implication was probably net unfair and I would make the question more explicit if I could edit the message; I'm sorry.

      My point about the computer, Internet, and so on is that we live surrounded by free lunches, the denial is a silly of propertarian piety, and that by extension the rest of your argument was so---that I'm not sorry for.

  99. Other Examples by Fujisawa+Sensei · · Score: 1

    This isn't the first time a patent has been siezed by a government. I beleive that also happend with Shockley and the transistor.


    --
    If someone is passing you on the right, you are an asshole for driving in the wrong lane.
  100. IP? What is IP? by Artemis3 · · Score: 1

    Hahahaha, just Brazil? Wake up IP land! We most people outside don't give a crap about your stupid "everything must be ruled by the holy thesis of supply and demand by market, and only market forces alone" (which includes protecting the interests of the holy multinational companies instead of the people)...

    In my opinion, IP simply sucks, halts development and make lazyness; if ever, only a minuscule 5 years or so copyright/patent should be allowed, but nothing more.

    Sure, your holy corporations won't make as much selling viagra over here, but they sure will have fun researching "human cloning" and other "non permited in certain countries research" and then later will sell you the byproducts of the work carried over here.

    In case some of you wonders, yes, there is life outside USA borders, and, oh lord, people actually think different!

    (time to start your holy market force inquisition/crusades..)

    --
    Artix
    Your Linux, your init.
  101. Property needs Responsibility by extensive · · Score: 1


    The social concept of property is based on the fact that the community as a whole profits from it. At least that was the idea, at first. Then came modern times and big companies.

    Society still grants companies (and also single rich persons) protection of their property. To justify this grant, which is not a natural right, although many seem to think of it in this way, the companies must give something back to society in return. They have to act responsibly and with a view on the benefit of society.

    If they don't, society has no reason at all to continue that grant. Brazil has realized that and they are doing the only reasonable thing: revoking that grant.

    1. Re:Property needs Responsibility by mimbleton · · Score: 1

      What a piece of crap.
      This is precisely how Staling,Hitler and others justified ANY sort of abuse - you are not beneficial and society can revoke your right to anything.

    2. Re:Property needs Responsibility by Anonymous Coward · · Score: 0
      This is precisely how Staling,Hitler and others justified ANY sort of abuse - you are not beneficial and society can revoke your right to anything.

      So, were you bringing up Hitler and Stalin to illuminate some aspect of your position, or are you just pissing poison into the well?

    3. Re:Property needs Responsibility by mimbleton · · Score: 1

      Who do you care ?
      You don't exist.

  102. Missing the point by Daikiki · · Score: 1

    The discussion here seems to focus on whether the Brazilian government is justified in breaking international patents in order to provide their ill with much needed medicine. However disgusting I find it that such a batlle is being fought over the heads of AIDS sufferers, and that so many people here seem to think that death is preferable to patent infringement, the point begging to be made is a much larger one.

    Should commercial companies be developing life saving drugs at all? I'm a capitalist, don't get me wrong. I believe in the free market, I understand the price of developing these drugs is astronomical and that if a commercial corporation develops them it wants to make money out of it. But the fact remains that a drug like nelfinavir was dceveloped and is being produced not for the benefit of the people it helps, but primarily for the benefit of Roche and its stockholders. That's wrong. Just plain wrong. We, as mankind, need an organization that develops drugs like this, not for commercial benefit, but for humanity. Brazil is just the tip of the iceberg here. The are countries far poorer than Brazil with a much higher infection rate. How does Ghana pay for this stuff? When commercial considerations cost lives, those considerations should be taken away. That can only be done, as far as I can see, by developing these drugs in a non-profit environment. Not everything begins and ends with dollars. At least it shouldn't.

    I know, it's a pipe dream to think that, in the cash-hungry corporate world we currently live in, anything like this can be done on a not-for-profit basis, but if we don't stop worshipig the dollar with quite the fervor we do now, I don't think our future looks too bright.

    --
    I want the fire back.
  103. People, please by bradasch · · Score: 1

    As I read the comments here on Slashdot, somethings hits me...

    Do you really think that the pharm industry is going bad and needs this money?

    Besides, do you really believe that they're the only people on Earth that can do R&D of drugs? Or that the profit they have is used solemnly only for R&D?

    This industry is making money on several drugs they didn't research or develop... That, I suppose is right?

    I don't intend to say everything is wrong in the industry, but they can spare some bucks to a poor country to save some lives. I'm not even saying that we should never pay for royalties in drugs, but the price should take account the affordability of the people buying it. Saying "I did the research, so I'm entitled to charge whatever I want to" isn't what I would call being nice.

    Sometimes things aren't only about profit.

    Guilherme Bradasch

  104. Law Or Lawlessness? by Artagel · · Score: 4, Insightful

    How Brazil handles itself *after* its decision to go ahead and manufacture the drug will define whether Brazil is a country that stands for the rule of law or for the rule of lawlessness.

    Brazil is exercising one of the undisputed powers of a sovereign -- to take what it needs. A lawful sovereign pays reasonable compensation for what it takes. Thus, in civilized countries, when land is taken to build a road, the landowner does not get to veto the road, does not get to extort an unreasonably high price for being the last piece of land needed to build the road, etc. He gets reasonable, just compensation, and such a right is guaranteed by the courts of the country.

    In common law countries the "rule of necessity" is not limited to sovereigns. For example, you are permitted to tresspass in certain conditions because of necessity. A classic example is a ship docking to avoid a killer storm. That does not mean not having to pay afterwards for what you take, or what you damage, however. "Necessity" defines conditions where you can "take it and pay a reasonable amount."

    Brazil had a contract with Roche to provide drug that it is going to honor. Brazil is gearing up to provide its own generic version of the drug after the contract expires because it has been unable to reach agreement with Roche as to a price at which Roche will continue providing it. Brazil is taking. If it decides to take for free, it stands as an example of lawlessness. In such a case, it should be punished heavily by international trade organizations.

    If it taking because of the impending necessity, with the intent to pay an agreed amount afterward, then it really is a tempest in a teapot. "Reasonable" in this case is certainly *not* what the generic would cost on the generic market. Reasonably prices are not negotiated under the threat of imminent death -- that's why courts often settle the "take and pay" price assigned to necessity situations.

    1. Re:Law Or Lawlessness? by vidarh · · Score: 2
      You disregard the very basis of patents and copyright: Neither are property at all. They are limited monopolies granted to encourage innovation for the benefit of the public. If the public doesn't see a benefit (the drugs are too expensive, for instance), there is no reason for
      the government to keep honouring the patents.


      Read a book on the history of intellectual "property".

    2. Re:Law Or Lawlessness? by Absynthe · · Score: 1

      I had to read that a few times to understand what you were getting at. You've basically outlined article 31 of the TRIPS agreement and specified how they would be in compliance with the treaty.

      That's all well and good, but you don't see any problem with patents killing people? The world has gone insane, the US threatens to crush China with the WTO over some pirated records but their horrible human rights record is no problem to their most favored nation status.

      Everyone needs to step back and re-evaluate our priority's. I like my money also, but I'm not willing to let people die over my patent rights. We didn't always have 10 year patents on drugs and the pharmaceutical industry didn't die.

      If I owned pharmaceutical stock, I wouldn't be able to sleep at night. That or maybe I should buy one share so I can complain that I'd rather see a slower growth rate on my stock and some tighter profit margins than kill people for a few more dollars.

      Jesus, there are some cruel people in here

    3. Re:Law Or Lawlessness? by Anonymous Coward · · Score: 0

      Brazil had a contract with Roche to provide drug that it is going to honor. Brazil is gearing up to provide its own generic version of the drug after the contract expires because it has been unable to reach agreement with Roche as to a price at which Roche will continue providing it. Brazil is taking. If it decides to take for free, it stands as an example of lawlessness. In such a case, it should be punished heavily by international trade organizations.

      And all other bastards who don't give a shit about human life

  105. This is a sticky issue. by NateTG · · Score: 1

    Lets start by saying that what Brazil is doing is illegal. I doubt anyone is arguing with that.
    Now, regarding the issue of it being wrong.
    I don't know about this particular drug, but there are many pharmaceuticals that are like software: Once you have all the necessary information they are very cheap to produce. As with software there is a large up front cost. Funny that when people here start talking about software patents they're screaming, but when all that's involved is people dying then they're willing to let them die.
    If was drunk, and there was someone bleeding to death, barring other options I probably would still try to drive them to the hospital. That's right, illegal act to save someone's life, even a complete stranger's. Heck, I'd probably be willing to steal a car to do it.
    Now, Brazil is stealing this roche drug. Trying to save people's lives. Can't say that it's wrong from my point of view.

  106. Wrong! by richieb · · Score: 1
    Do governments want to pay for medicine to be developed? No

    Actually yes. For example see this article in Salon.

    ...richie

    --
    ...richie - It is a good day to code.
    1. Re:Wrong! by Chris+Hind · · Score: 1

      And Brazil's contribution to the development of this drug was how much? Roughly? In dollars?

      I'll take a wild guess: $0. They can have all the pills that that amount can buy for free, I won't argue.

      --
      nal 11
    2. Re:Wrong! by richieb · · Score: 1
      Actually, I don't know how many Brazilian scientists contributed to the research. But in any case, since the basic research was done with my tax dollars, I'm happy if other people (even if they haven't paid) benefit from it.

      I don't see anything wrong with helping people when we can. Perhaps one of those people whose live we save today, will save your life in the future. You never know.

      ...richie

      --
      ...richie - It is a good day to code.
    3. Re:Wrong! by Chris+Hind · · Score: 1

      Like I said to some other poster: if we wanted to donate these drugs to these countries, by putting a couple of percent on income taxes to pay for it, that would be fine. Fancy that? Then campaign and vote for it. Don't be surprised if the drugs companies campaign against having their investments stolen, though.

      I don't see anything wrong with helping people. But disincentivising drug companies from putting money into diseases affecting the developing world is a pretty fucking stupid way of helping anyone.

      --
      nal 11
  107. Re:You know, the likely response is going to be. . by Alex+Belits · · Score: 2

    You can't patent ANYTHING without publishing it, and you won't get any data from universities without cooperation. Drugs are not Coca-Cola.

    --
    Contrary to the popular belief, there indeed is no God.
  108. Boo-frikin-hoo by cdgod · · Score: 1

    This reminds me of the RIAA bitchin about piracy affecting profits when they are now making more revenue and net income than they have in their entire history.

    Let's have a look at the poor poor drug companies... They make you think a little charity would kill them.

    Roche

    In the first half of 2001 the Roche Group achieved consolidated results of 14,5 billion Swiss francs. This represents a growth on an adjusted basis of 6% in both Swiss francs and local currencies.

    Group operating profit and net income were stable at 2,4 billion Swiss francs and at 3,0 billion Swiss francs respectively. As expected the EBITDA margin and the operating profit margin decreased slightly.

    PFIZER INC = $256.4 Billion

    Pfizer Inc. is a global pharmaceutical and consumer products company which discovers, develops, manufactures and markets innovative medicines for humans and animals. For the six months ended 6/30/01, total revenues rose 8% to $15.33 billion. Net income from continuing operations totaled $3.72 billion, up from $945 million. Results reflect increased sales of Lipitor, Neurontin, Zyrtec and Norvasc and a $1.79 billion reduction in costs related to the merger with Warner-Lambert.

    Merck = $159.3 Billion

    Merck and Co., Inc. is a pharmaceutical company that discovers, develops, produces and markets human/animal health products and services. Merck also provides pharmaceutical benefit services. For the six months ended 6/30/01, sales rose 27% to $23.24 billion. Net income rose 8% to $3.47 billion. Results reflect strong growth in worldwide human health sales, and other newer and established products, partially offset by higher materials and production costs.

    (I got these mostly from their websites and quote.yahoo.com)

    So these three alone have over $10 billion in PROFITS. That's after all their research into drug development has been paid. And they want more. Now, I can understand that if they were running at a loss...fine - raise the price of drugs in rich contries to pay of the R&D and give the drugs (AT COST) to poorer nations to improve their goodwill.

    ---

    --
    This .Sig is left intentionally humourless.
    1. Re:Boo-frikin-hoo by Anonymous Coward · · Score: 0

      you forget to add outstanding debt. that will shrink those "profits" abit

    2. Re:Boo-frikin-hoo by clink · · Score: 1

      Yep, those rich mega corps have got plenty. Let's just take their stuff in the name of "the public good".

      By the way, you are now considered wealthy and we're taking your stuff too. Please be out of your house by 8am. Leave all posessions.

  109. You raise some very good points... by chrome+koran · · Score: 1
    However, according to the article:
    Federal officials said they were unsuccessful in talks with Roche to lower the prices the country paid for nelfinavir.
    and
    ...the health ministry now spends $82 million per year on the nelfinavir, in sum using up 28 percent of its annual budget to treat AIDS patients..
    and
    Similar negotiations with other large drug companies, such as Merck, have successfully reduced the prices of medications, the ministry said...
    So, it's not like they didn't try to negotiate a reasonable price. I wasn't there, so I don't claim to know whether or not the parties negotiated in good faith. But this is not a new drug, and I sincerely doubt (although I don't know for sure) that Roche is still in the red on this one. I think they have more than recouped any R&D costs by now, and should be willing to negotiate on price with an underdeveloped country that is trying to provide social welfare programs.
    --

    It's not funny till someone gets hurt.
  110. nice try, but... by tewwetruggur · · Score: 4, Interesting
    ...you have unfortunately replied to someone who works in the pharmaceutical industry.


    I do wish people would stop it with the "how are they going to fund research?" crap. If you look at the big picture of drug research, and where the costs really are, you would see that a lot of it is inflated numbers caused by "economic factors" and other such nonsense. That is how a lot of universities are able to continue to do excellent pharma research. The companies are hindered for less noble reasons than academia.

    --
    Hi! This is the Sig, blatantly attached to the end of this comment.
    1. Re:nice try, but... by Harmast · · Score: 3, Insightful
      I do wish people would stop it with the "how are they going to fund research?" crap. If you look at the big picture of drug research, and where the costs really are, you would see that a lot of it is inflated numbers caused by "economic factors" and other such nonsense.


      I think here the problem is they mean one thing when they say R&D and you hear another R&D.


      As I pointed out above the real R&D cost for drugs is not in research as you seem to mean: isolating chemicals, testing initial effectiveness, but in development: mass production, human toxicity, and, most importantly, FDA approval.


      In general university researchers do much less pharma research in those areas than drug companies (when was the last time UConn got approval for a drug). Those costs, which are often incured for a drug that will never see approval for various reasons, are the real R&D costs.


      Unfortunately, drug company PR flacks just use lumped costs when explaining this instead of breaking it down (talk to the people on the clinical side of R&D of a drug company to get a better picture) thus leading to said confusion.

      --
      Herb
      Again, feel free to sentence me to death if my questions annoy you. I'll come back in 5 minutes anyway. -Sythi
    2. Re:nice try, but... by Anonymous Coward · · Score: 0

      I did research in a neuropharmacology lab at a very large and old state univeresity. Rest assured, we were very tight on money. The situation was ismiliar for most other researchers at the university. Obviously you have no fucking idea what you are talkin about.

    3. Re:nice try, but... by Anonymous Coward · · Score: 0

      As I pointed out above the real R&D cost for drugs is not in research as you seem to mean: isolating chemicals, testing initial effectiveness, but in development: mass production, human toxicity, and, most importantly, FDA approval


      But guess which part the patents cover.

  111. I might be wrong... by SaturnTim · · Score: 1

    I might be wrong, but last I heard, this isn't a CURE for aids. This is just delaying the agony. Even worse, the people on the drugs might believe they are healthy, and have a greater chance of infecting others.

    Is this worth breaking international law?

    If we were talking about a cure, something that could wipe out all AIDS in the country, maybe then I would side with the people, and say "Break the law". But now, this is just a short term improvement in how the ill will live, and I think the drug company has the right to charge for it.

    --ST

    --
    http://www.theMediaBunker.com
  112. Ashamed by TroyFoley · · Score: 1

    I see but many of my American countrymen rushing to the defense of the drug companies and their patents, all in the name of "R&D" continuation, or lack thereof should ignoring patents become a trend. To a country of workers who wouldn't, nay, couldn't afford even the most discounted of prices, I applaud Brazil's bold move to tell the drug cartel to take their patents, roll them up nice and tight and... *ahem*.

    The notion that they will stop researching if Brazil or ALL third world countries (South Africa comes to mind as an example) disregard their patents is absurd, what with America alone being diseased enough to keep them running. Cancer treating patents being snuffed in soandso? Push cigarettes more in America. AIDS treatments gone generic in soandso? Whittle off STD-discussions in public schools. I can think these up, they can, and companies that don't die off. Evolution with the cruelest of corporations surviving. Whatever you think of this arguement, always keep this in mind.

    They do not need anyones sympathy.

    --
    After I have received the wisdom of good teaching, I will untiringly teach all people. - The Teachings of Buddha
  113. For the sake of liberty... by Improv · · Score: 2

    For the sake of liberty we must prevent and undo
    intellectual property protections. It is simply
    unacceptable that something that I may discover,
    a thought I may have, data that I might collect
    might be blocked or require a fee for my use.
    I assert that any piece of data, any idea, any
    thought that I might acquire or synthesize is
    something that I may use as I see fit, with no
    restrictions on that action as such, including
    sharing it with others or using it for various
    purposes.

    I will not comprimise on this.

    --
    For every problem, there is at least one solution that is simple, neat, and wrong.
    1. Re:For the sake of liberty... by sql*kitten · · Score: 2
      I assert that any piece of data, any idea, any
      thought that I might acquire or synthesize is
      something that I may use as I see fit, with no
      restrictions on that action as such, including
      sharing it with others or using it for various
      purposes.


      That's great, kid. Glad to hear it. Look forward to hearing from you when you've developed some groundbreaking theory, product or technique from scratch, with your own time and money.

    2. Re:For the sake of liberty... by omarius · · Score: 2
      I (the parent of this messy thread) agree with you!

      But I don't think I have a right to steal your discovery because I want to use it and can't come up with it on my own, either! -- supposing you did not like me, and did not want to share it (or sell it...).

      -Omar

  114. How will this hurt the drug companies? by uchian · · Score: 1

    I mean, they can't really be relying on countries as poor as Brazil for their revenue, that would be plain wrong. On the otherhand, developed countries whose people do not live in such deep poverty, should pay for the drugs.

    As long as Brazil doesn't try to profit from these drugs i.e. sell them to other countries, then I don't see a problem.

    However, I cannot help wondering if a black market will arise, where the drug is trafficked from Brazil and those in need who can't afford it, to those in developed countries who are simply too tight to pay for it.

  115. ignore all medical IP by Anonymous Coward · · Score: 0
    Yep - this is great. Now lets take it and run with it. Why should Brazil or anyone else stop with AIDS drugs. I know AIDS is the sacred cow of disease, but there are lots of others that need to be treated. Brazil should ignore the patents on new antibiotics and cancer treatments and any other drug people might be dying with. Yeah, that should work out well. Shoot, just ignore patents for anything that might remotely help people there.


    Or maybe that is not such a good idea. Ever go to Mexico and see how cheap drugs are there? Not just the generics, but the real deal from the US manufacturer stuff? Guess who pays the full costs on that? You guessed it - all the citizens of the good old US. See, the EVIL drug companies actually do give cut rate prices on all sorts of drugs already to prevent the Brazil's of the world from stealing their stuff.

  116. I have a question by WildBeast · · Score: 1

    I'm thinking... let's say some pharmaceutical company develops a drug that can cure AIDS, do they have to wait like two years to get their patent before being able to distribute that drug?

    I have no idea how it goes, does anyone know?

    1. Re:I have a question by Cro+Magnon · · Score: 1

      If a pharmaceutical company develops a cure for AIDS, the proper procedure is to sit on it. If any other company finds this cure, they can sue the pants off them, and if keeping people on short-term treatments ever becomes unprofitable, then, and only then, will the cure be released.

      --
      Slow down, cowboy! It has been 4 hours since you last posted. You must wait another few hours.
  117. WRONG! BRAZIL WILL PAY THE PATENT! by Anonymous Coward · · Score: 1

    First, sorry for my English, I am from Brazil.

    The role thing is misunderstood.

    Brazil tried many times to reduce the price of one drug from Roche, that alone represents more the 28% of the total investiment in AIDS in Brazil.

    Since it failed, Brazil decide to produce the drug and will PAY FOR THE PATENT, instead of import the drug. This will reduce the cost about 40%.

  118. Roche v. Brazil by john82 · · Score: 1
    Brazil has decided to suspend international law in favor of their populace over those greedy global-economy drug companies who developed the drugs. We can also rest assured that the Brazilian companies that produce these AIDS pharmaceuticals (or through taxes, graft, what have you the Brazilian govt) won't make a dime of profit themselves.

    Right?

  119. Show me the money by Anonymous Coward · · Score: 0

    Ok. I work for a Pharma, and if I can't get money by charging for the products THAT I INVENT, how will I be funded? By kind-hearted people like you? I doubt it. Are you going to send me a check for xxx million dollars, on a promise that I *might* come up with a cure for something? Again I doubt it. Public funding is a great addition to the greatly needed funds, but reselling the product recoups a far great amount of the R&D costs.

  120. Brazil is a Sovereign Government by Foochar · · Score: 2, Insightful

    Brazil is a sovereign government. In other words they have the right to decide what the laws in their country are. If they decide to honor human life over intelectual property that is their choice. In the same way there are countries in which software patents do not exist. In those countries you could implement one-click shoping and there is nothing Amazon could do about it. Just because there is an international agreement dosen't mean you have to follow it. Look at the U.S. and Dubya's opinion of the Kyoto accord. The international community agreed to reduce the emission of greenhouse gases, but the U.S. is a sovereign power, and doesn't have to abide by it if they don't want to.

    International politics are no different then playground politics. There are two kids playing on the playground Tom and Jack. Jack wants to play on the swing, Tom dosen't want him to. Tom can do a few things, he can try and reason with Jack, he can threaten Jack, or he can go get the teacher. The pharmasucitcal companies and their parent nations can try and convince Brazil this is a bad thing, they can threaten Brazil with sactions or military retaliation, or they can go running to the WTO. The teacher(WTO) can still only do so much though. If Jack decides that the fun from playing on the swing is worth going to the principal's office then there isn't much the WTO can do. Especially if Jack knows that his did won't punish him when he gets home. On the field of intenational politics, the same as on the playground one rule reigns over all others, might makes right. If the U.S. wanted to invade Brazil and stop them, they could. But the U.S. isn't going to, but this little IP dispute isn't worth a war to anyone.

    --
    "You can't fight in here! This is the war room" --Dr. Stra
  121. Life before dollars by SilentChris · · Score: 2
    "from the life-before-dollars dept."

    Unfortunately, this ends up being a lot more philosophical a statement than it initially seems. These patents, and the money they make, may not affect the bigwigs all too much at the pharmaceutical companies, but they do affect the lower workers who need the patent money to put bread on the table.

    There are a variety of reasons why drugs are as expensive as they are, not the least of which is greed. But also insurance premiums, lawsuits, and salaried employees all play a part in raising prices, so making an all-inclusive statement that this move provides "life before dollars" really isn't exactly true. Money is a system that affects everyone, and some people's lives *will* be screwed by the breaking of the patent law.

    1. Re:Life before dollars by Herstel · · Score: 1

      Money is a system that affects everyone, and some people's lives *will* be screwed by the breaking of the patent law.

      Philosophical as you said, ethical as well. Personally I don't think that anyone's life in Roche will be screwed up, just imagine if Brazil decided not to produce a drug at all. AIDS is a serious pandemic disease, Roche is a rich company holding many patents, many lives in Brazil will be saved. Breaking that patent law is an exeption.

    2. Re:Life before dollars by jafac · · Score: 2

      um - insurance premiums=greed
      lawsuits=lawyers=greed
      drug marketing=greed/stupidity
      marketshare=greed
      shareholder profits=greed
      a new bonus program for executive staff=greed

      salaried workers=a drop in the bucket compared to the above.

      --

      These are my friends, See how they glisten. See this one shine, how he smiles in the light.
  122. Here's another example by sup4hleet · · Score: 1

    Eli Lilly (couldn't find stats on Roche quickly, so I picked any old famous drug maker)in the last six months had $5.84 billion in sales, of which $1.63 billion was profit (go ahead and check biz.yahoo.com symbol lly).

    And that's NET after R&D is paid for. Remember these are companies, any revanues spent on anything, including R&D aren't taxed. Any traditional financial/manufacturing/etc. company would jiz themselves for a 28% profit margin, most have 3-10%

    So how much money should a company make off of a drug? More than you and your extended family can earn in 200 years not ajusted for inflation?

    1. Re:Here's another example by dameatrius · · Score: 1

      If they are making this much profit, other companies will come in and do the same as long as it is still profitable. The problem is, this money feeds right back into the company (maybe not all of it, but a good portion of it) to continue research. If you also looked around, revenue is expected to decline for the next year+. It sounds good to do something to save lives and people will be dancing in the streets about what a great move this is, but the fact is, if one country gets away with this, others will follow. In the end, their won't be any money in Pharmaceuticals and R&D will stop and more people will die. There are trade offs and this is not a good one. Human nature says that for the majority of people, "If I don't get something out of doing x, why would I do x?".

      Good for Brazil, they have staged a great coup, unfortunately, they invalidate all patents and bend the world over to take it up the ass. I can now go steal the information on how to build a cleaner burning engine from Honda and build a cheaper car using their technology without paying any patents because I am saving lives by lowering pollution and decreasing carcinogens in the atmosphere.

    2. Re:Here's another example by Anonymous Coward · · Score: 0
      I can now go steal the information on how to build a cleaner burning engine from Honda and build a cheaper car using their technology without paying any patents because I am saving lives by lowering pollution and decreasing carcinogens in the atmosphere.

      You don't seem to understand. People die from AIDS, whereas people don't die from not having a car. No one ever forced you to have a car, right?

  123. There is no argument since ... by Anonymous Coward · · Score: 0

    The value of human life > *. Never forget that.

    Another thing, don't give me any "what ifs" since people are dying horrible deaths NOW!

  124. Re:Bullshit- no... by Anonymous Coward · · Score: 0

    Another plague (bubonic [sp?]plage killed a great number of people in Europe) except worldwide this time - wonderful.

  125. Carry the idea to its logical conclusion by dughat · · Score: 1

    There are a lot of posters hear failing to see the big picture. AIDS is a big, famous, scary disease, so of course the medicine should be free. But Heart Disease makes you just as dead. So maybe that medicine should be free, too. Oh, cancer makes you dead too? Well, lets make those drugs free, too. How about infection? You can die of infection in the third world, too. Lets make them free, too. We'll keep paying for Prosac, because only rich people take that and you don't die of depression (usually). So what about when the next big disease comes along. Who finds the cure? I'm sure all the independently wealthy scientists will work on that, since they don't need a paycheck, but will they find it? Or we could just become socialist, so the government decides which diseases the scientist work on, because all the successful counties in the world are Socialist.

    The harsh reality is that rewarding people for finding a cure means that cures will get found. More people will live longer, better lives who have contracted AIDS, high blood pressure, cancer, or infections, because there was incentive for people to find cures. Not all will live, but if there were no cure (or treatment) no one would live. And if there were no incentive, very few cures would be found. Is the current balance between costs and rewards perfect? Probably not. But good luck making it perfect.

  126. Moral money making by peripatetic_bum · · Score: 1

    While its true that it costs a lot of money to make medicines that save people, I think part of the blame should be laid at teh feet of the drug makers themselves. Getting rich off of sick people who have no other choice strikes me as patently offensive.

    Yes, its true that they have intellectual property rights but its also true that you are dealing with deparate people and governments. In an Ayn Rand view, we coudl let all those people die, and make sure that the next generation is educated and will not need the hand outs, but that is simply too black and white a view.

    I am reminded of the argument that if you have a loaf of bread and then men next to you has nothing and he has children to feed, you can argue all you want, but he is going to go after your bread.

    The point (sorry for rambling) is that perhaps its time that this sort of research for the public (unless we want to say that drug research is not for the public, but only for those that have money to pay) should go back to the university where IP will no longer apply (look at the fiasco that Wisconsin is generating but claiming that anything that someome else makes fromt their stem cells wil have to be ok's by the Wisconsin department).

    I thinkk that as healthcare becomes more and more a public commodity (it never really was until very recently) that we will have to start treating it as such. Just as you can not own the water and deny it to the thirsty, I'm afraid to say that the same thing is happening to medicine and to drug research in particular.

    Anyway, thanks for reading

    --

    Sigs are dangerous coy things

  127. Why didn't the company go for the PR coup? by clickety6 · · Score: 1

    Considering the amount of money that the drug company spends on PR, why didn't they just make a special, very-low cost licensing deal with the BRazilian government to allow them to manufaxture cheap pills purely for use in Brazil i.e. they can only produce what they can use. Think of the massive amounts of positive publicity that could produce for the patent holder at very little cost, because the Brazilian government could never afford to pay for the pills anyway!

    --
    ----------------------------------- My Other Sig Is Hilarious -----------------------------------
  128. Um, like, save the world and stuff. by zpengo · · Score: 1
    Just because software patents are patents on math & therefore stupid doesn't mean all patents are stupid. Pharaceutical R&D is intensely expensive. Screwing the companies that fund research is a bad solution to what is at heart a political problem.

    If someone doesn't screw those companies pretty soon, they won't be alive long enough to collect on any of that.

    The disturbing thing about most of the comments I've read here have exhibited the same mentality that caused the disease to spread so much in the first place: It's the belief that AIDS is *their* problem.

    Brothers and sisters, AIDS is our problem. It makes the bubonic plague look like a bad case of hiccups. After years of being bombarded by pleas to practice abstinence or safe sex, people are still so numbheaded that they go out and spread the disease anyway.

    When a city is burning and the guy with the fire truck isn't helping because the citizens can't afford to pay what he thinks he should get for his services, there comes a time when you just have to take the bastard out and steal his truck.

    --


    Got Rhinos?
    1. Re:Um, like, save the world and stuff. by Anonymous Coward · · Score: 0
      Brothers and sister!--WTF. Hey hippy-dude, do you see people being carted off daily in NewYork that are AIDS casualties. AIDS is deadly, but it is no where as infectuous as the plague. A male getting it from a female is a 1/500 chance -- with an infected person. The plague can be spread by coughing.

      here is an interesting article concerning the infectiousness of HIV:
      http://www.fumento.com/comment.html

    2. Re:Um, like, save the world and stuff. by krlynch · · Score: 2

      Diseases like AIDS are, I agree, not the problem exclusively of the diseased; society (through government funding of basic R&D and legal protections for developmental R&D, but not necessarily the current system) must contribute to eliminating or controlling the disease.... but the statement

      AIDS ... makes the bubonic plague look like a bad case of hiccups.

      is patently idiotic. AIDS has no where near the impact of the bubonic plague, or malaria, or typhoid, or polio, or influenza, or tuberculosis, or any of a host of other diseases. Except for a few subsaharan countries where social structures guarantee high rates of infection (for EVERY STD by the way....), it has no where near the rates of infection, death, illness, incapacitation, and maiming of those other diseases. And unlike those earlier diseases, MOST (certainly not all, but most) of the people being infected by AIDS can avoid those infections by changing their behavior (which you acknowledge when you say: people are still so numbheaded that they go out and spread the disease anyway).

      So, while AIDS is a tragedy, and we should be doing many things that we aren't doing to help fight the spread of the disease, to claim that the situation is on par with the most destructive epidemics of the past and present is pandering and clearly ridiculous.

    3. Re:Um, like, save the world and stuff. by Anonymous Coward · · Score: 0
      Brothers and sisters, AIDS is our problem. It makes the bubonic plague look like a bad case of hiccups.

      Huh??? Do you actually know anything about either disease? After your hysteria has passed, I'd suggest reading up on both.
    4. Re:Um, like, save the world and stuff. by eaolson · · Score: 1
      AIDS has no where near the impact of the bubonic plague, or malaria, or typhoid, or polio, or influenza, or tuberculosis, or any of a host of other diseases.
      In the US, at least, the plague, malaria, typhoid, polio, influenza, and TB have very little impact. They're virtually unheard of. (OK, the last two less so, but they're still quite rare.) Now if you want to talk about historical impact of these diseases which have been around for most of human history compared to HIV which we discovered only about 20 years ago, well, the jury's still out on that one. Why don't we meet up again in a thousand years and discuss it?
      Except for a few subsaharan countries where social structures guarantee high rates of infection (for EVERY STD by the way....), it has no where near the rates of infection,
      Yeah, but it's hard to die from the clap.
      it has no where near the rates of death, illness, incapacitation, and maiming of
      The rate of death from AIDS is virtually 100%. Not so for ALL of the diseases you mentioned.
      not all, but most) of the people being infected by AIDS can avoid those infections by changing their behavior
      You're talking about regions of the world where often people do not acknowledge that HIV causes AIDS at all, let alone understand how it is spread. Why would they change their behavior?
      So, while AIDS is a tragedy, and we should be doing many things that we aren't doing to help fight the spread of the disease, to claim that the situation is on par with the most destructive epidemics of the past and present is pandering and clearly ridiculous.
      This very morning I heard one estimate that 1 in 2 Africans in this century may die from HIV/AIDS. How is that anything other than one of the most destructive epidemics in history? Even the plague didn't kill more than 1/3 of Europe's population.
    5. Re:Um, like, save the world and stuff. by Anonymous Coward · · Score: 0

      This very morning I heard one estimate that 1 in 2 Africans in this century may die from HIV/AIDS. How is that anything other than one of the most destructive epidemics in history? Even the plague didn't kill more than 1/3 of Europe's population.

      Because those Africans are black, and those Europeans were white.

  129. No money by Johnny5000 · · Score: 2, Interesting

    If Brazil has no money to buy the drugs, we get one of two situations:

    1. Brazilians with AIDS have no money to buy drugs. Therefore, the drug companies get no money from them, and the AIDS patients die.

    or

    2. Brazilians with AIDS have no money to buy drugs. The Brazilian govt violates the patent, the patients get their drugs, but the drug companies get no money from them.

    Looks like #1 is a lose-lose situation.
    At least in scenerio #2, the people get their drugs.

    -J5K

    --
    The libertarian solution to the failures of capitalism is to apply more capitalism til the failures are fixed.
  130. Imagine... by Anonymous Coward · · Score: 0

    A lot of people are saying how the poor drug companies have to make a profit (err, hand over fist profit) or else they will shut down and stop producing cures (err, temporary treatements) to diseases. There would be no choice but to make the public pay for all R&D on drugs.

    Of course this posibility is quite far fetched with drug companies raking it in like they are now. But if you can, just imagine how great it would be.

    First of all, remember that public funds account for a huge portion of the drug companies R&D budges (something like 40% I think). That's not counting the public funds that go into the basic science behind it all (the chemistry, the biology, etc).

    Can you imagine what the world would be like if we covered the other 60% and drugs were created and sold with the purpose of helping people instead of making shareholders millions. A world were you would pay a a little more in taxes, but where you would buy medicine for the tiny cost that it takes to produce it. A world were the brightest minds worked on cures to real diseases instead of helping Bob Dole get it up.

    Having a hard time with imagining something so different huh? Me too.

    1. Re:Imagine... by metachimp · · Score: 1
      A world were you would pay a a little more in taxes


      Yeah, right. Considering how much people bitch and moan about paying taxes now.


      Whenever a property tax hike is proposed to fund strapped local schools, people scream and shout about it. They want all the services, they just don't feel like paying for them. Don't get me wrong I agree with your statement, but asking people to pay higher taxes, even if it means something cool like universal health care and top flight public schools, is asking for trouble.

      --
      The system has failed you, don't fail yourself. --Billy Bragg
  131. To paraphrase Bertolt Brecht... by ralphbecket · · Score: 1

    Medicine first, then ethics.

  132. Re:India, Brazil, China... half the planet already by Bobo+the+Space+Chimp · · Score: 1

    > Operating systems are incredibly expensive to develop.

    No they are not. Was the original DOS some massive thing requiring billions? No. There are plenty of RTOS's (Real-Time Operating Systems) that have optional windowing systems, comples graphics primitives, TCP/IP stacks, Java virtual machines, etc. Why not slap together a CPU and stuff it onto one? Why, because there are no apps for that.

    --
    I am for the complete Trantorization of Earth.
  133. What good are drugs that nobody can afford? by Anonymous Coward · · Score: 0

    Considering the vast majority of people who need treatment for AIDS are far below the poverty line, speaking globally, maybe drug R&D can afford to be "stifled" for a little while so that its benefits can actually be used to heal people rather than earn money.

    You're right, it probably will stifle research somewhat, but we aren't going to go back to "amputate or medicate". Research will still go forward. But in addition, the benefits of that research will be accessible to those who need it most, and not just to those who can afford it.

    Simple economics: You can always throw more money at research in the name of "advancing science". That doesn't mean that taking money away from research when people need treatment is a move backwards or anything of the sort. As the article clearly states, the government attempted to negotiate for lower prices, but were turned down. What do you want them to do? Allow their citizens grow ill and die because of a foreign patent law?

    Advancing medical research is laudable, but not if those advances are used for profit instead of for healing. That is the issue here, and I think that the Brazilian government made the rational choice.

  134. News From The Future.. by RedSynapse · · Score: 1

    Today it has been announced that five major drug companies have decided to cease their research into new AIDS combating drugs. The companies have stated that they can no longer recoup the billions of dollars of research and testing that goes into developing the drugs, as many countries have begun manufacturing AIDS drugs without paying royalties to drug companies. Many of these royalty free drugs have found their way into foreign markets, such as the US and Europe, and have depressed global sales for the drug companies that have developed them. Spokespersons from Merck, Roche, and GlaxoSmithKline have stated that they will combine their previous AIDS research teams into a new super-research taskforce with the aim of developing a drug that will help prevent heartburn.

    1. Re:News From The Future.. by tweek · · Score: 1

      Thank you! Somebody realizes that THIS was the reason that patents were invented.
      Software patents excluded (reform needed), what is a company's motivation to continue to invest in important research when they can't make any money from it?

      --
      "Fighting the underpants gnomes since 1998!" "Bruce Schneier knows the state of schroedinger's cat"
  135. 2 Billion R&D == 5 Billion profit by slashkitty · · Score: 5, Informative
    Just take a look at their profit statement:


    http://www.roche.com/home/investor/inv-finance/i nv -sales-key-figures-hy-2001.htm


    They are pulling in cash hand over fist. Now, why couldn't they negotiate a lower price w/ Brazil so that wouldn't send half their budget to Roche?

    --
    -- these are only opinions and they might not be mine.
  136. From the Boston Globe: by mblase · · Score: 2
    But instead of educating and changing killer lifestyle habits, their government steals IP. This world is going to shit. But that's just MHO.
    Brazil is widely regarded as having a model anti-AIDS program among developing countries, and already produces generic versions of eight drugs for AIDS cocktails. Those drugs, distributed free to people with HIV/AIDS, are not covered by patents in Brazil.
    Sounds like they're doing all they can so far. What it comes down to is that, despite all the travel-agency posters of Brazilian beaches, Brazil is still considered a developing country, with all the economic disadvantages we Slashdotters can't hope to understand.
  137. Hell Yeah by haz-mat · · Score: 1

    Being a socialist i must say that this is a victory for the proletariat. On a human side one has to realize that no one has the right to profit off an epidemic and its great that finally a nation, even a 3rd world one, is ready to stand up against this bull shit. Peace
    -haz

  138. If there were real competition, this wouldn't be by R@Bastard · · Score: 1

    This is the kind of thing that "The Market" is supposed to solve, right? If the Roche would rather not sell than lower its prices, surely some other company should be able to sell to that market.

    The patent is the obstacle. Nobody else can manufacture the drug, because it's Roche's patented drug. Sure, they (probably) deserve to have a TEMPORARY monopoly on the drug to recoop their R&D costs, but this is a situation where the market is COMPLETELY FAILING. All of the religion about the "Free Market" this and that completely breaks down if monopolies are involved, even temporary ones.

    1. The public good is not being served (drugs not reaching sick people
    2. Roche isn't making money, because they're not selling to this market

    In this situation, everyone loses. So, Brazil's government is basically saying, well, we tried proper channels, and it didn't work. We still have sick people, so we're forced to break the law.

    Governments all over the world have a long history of throwing aside the rules and morality when an "emergency" is deemed. Sometimes those emergencies are crap (flag burning, kiddie porn, Reefer madness, protecting Kuwait) and sometimes they're not. Of course, that's according to my beliefs. I expect other citizens would disagree.

    It's sad, because you want to believe that at the very least, the governments of the world would obey their own rules, but COME ON! That doesn't happen.

    I for one am glad to see that this time the rules and "what is Right" is being shoved aside in the interests of ACTUAL CITIZENRY rather than big oil or credit card companies.

    --
    Mucous membranes are the part of your brain that, like, make you think about mucous. --Beavis
  139. Not just damage to search for AIDS cure by Ratteau · · Score: 1


    So, in the short-term this may seem like a good idea, but in the long term it could do serious damage to the search for an AIDS cure.

    Yes! and damage every other medical research going on as well. People dont seem to realize that these companies have to use these profits to pay for all their failed research as well.

    I just finished reading a book, and I really hate it when people spew Ayn Rand quotes, but it looks like Roche is a real-world example in what she wrote about in Atlas Shrugged. I dont think the whold world is going this way, but this imaginary quote fits: "Oh, they're just a rich corporation, they make massive profits on this drug that is very cheap to produce, they can afford to give some of that away."

    Take away the reason they got into business, they will stop doing business. Simple.

  140. I wonder by mjgamble · · Score: 3, Insightful

    How many /.ers have worked for a pharmaceutical company? How many have seen 7 years of research go down the tubes after promising studies find that the drug has a serious adverse effect on .5% of the people taking it and the last 7 years of your life were for naught.

    Does anyone around here understand how business works anymore? Where do you think retirement funds get funded from? Corporations are not run by some maniacal CEO hellbent on a conspiracy for world domination. I'm not out for world dominatino. I know my manager isn't. I've met his boss and his bosses boss. At what level do people instantly turn evil?

    Why do you think companies spend, on average, $1 billion to develop each new marketable drug? For fun? A drug spends as much as 10 years in the research phase before going to market. Anywhere along the way it may be found to be a) not as affective as hoped or b) not safe enough to market. Rinse, lather, repeat. Assuming it does make it to market, it may only have 5-7 years before generic competition forces the original research company to stop selling the drug for any kind of profit. The government, btw, does not contribute any measurable percentage of the research cost to the private company.

    Don't like marketing? I hate it more than anyone else out there, I assure you. I see it every day and it makes me ill. But it helps make sales, and it subsidizes low income patients (free samples to doctors from sales reps mainly go to elderly and those without health insurance). And all those revenues go back to, guess what, research for more drugs.

    Don't like the pharmaceutical companies and their high prices? Don't buy their drugs. I will help keep them in business. I'm paying for a service (research). A drug's price isn't the price of materials or shipping really. It's payment for the service they did by spending time and money researching and refining a single compound out of tens of thousands that may help me live longer or better. But to turn around and say thanks and not be willing to pay for it is asking thousands of people to work for free and without reward for all their hard work.

    As much as I would like to think that helping my fellow man is enough of a reward, I know that it isn't. It doesn't pay my light bill or put food on the table or get me any of those nice shiny computers I play with. I work to make a living to pay for things that I need (and the extra goes to things I want). Extrapolate that up from the individual and you have corporations. That's just the way it is. They need money to pay the light bills, run their supercomputers, and pay the scientists. And you need to survive the drug pipeline (go talk to Bayer and Merck about how much those suck right now).

    [Disclaimer: none of this is representative of my employer, my clients, or anyone but myself. Two cents.]

  141. On the other foot: by mblase · · Score: 2
    Would you, as the leader of this country, REALLY allow people to DIE a slow, lingering, and very painful death just because a piece of paper says you have too?

    It's interesting, because that's just the problem most people have with George W. Bush's decision to go ahead with the US missile shield. Why risk having millions of Americans subjected to slow, lingering, painful death from nuclear radiation when we can just ignore the treaty we signed with Anti-Ballistic Missile treaty we signed with Russia all those years ago?

    1. Re:On the other foot: by DivineOb · · Score: 1

      You get a cookie...

      But course, no one will respond to this because they're liberal cowards...

      --

      I must burn in hell, suffer and pay for my sins
      But Gods the one who's losing, Satan always wins!

  142. What bothers me. . . by Anonymous Coward · · Score: 0
    . . .is that we have an infectious, deadly disease, and nobody is willing to touch the "third rail" of the AIDS Debate.

    You know, the "Q" word. Quarantine.

    1. Re:What bothers me. . . by jpostel · · Score: 1

      Infectious when passing bodily fluids (like blood and semen) between individuals. If it was airborne then quarantine might make sense, but sex and needles are not reasons alone. Education of the people is needed. people in the US and Europe barely understand HIV. If that is any measure of what it is like in the sprawling tin roof ghettoes of Sao Paolo, then Brazil needs to build schools instead of fences.

      --
      Ummm, Jon, aren't you supposed to be dead...? - Otter(3800)
  143. accepting responsibility by kootch · · Score: 1

    people don't want to accept responsibility for their actions.

    assuming i know that I can get AIDS through unprotected sex with an infected person, and I then go and have unprotected sex with an infected person, am I then revoking my rights to bitch and moan that I got AIDS? I believe so.

    but most people don't for some reason. I got AIDS, so my government should now get me the drugs I need for free/cheap so that I can now save myself and/or continue my risky lifestyle by disregarding a company's hard and expensive work to find and create cures/vaccines/other drugs to help AIDS victims.

    Sometimes even calling them "victims" is a misnomer... simply for the reason that I feel many people aren't victims, but are culprits.

    1. Re:accepting responsibility by Anonymous Coward · · Score: 0

      Absolutely wrong.
      I can't figure out someone not worried about having AIDS because knows about the drug distribution.
      As ppl say here:
      "There's no drug against prejudice"
      No government action will reduce the fear of other against those with HIV. If lack of information can take someone to be infected, the same lack of information causes the fear of living near to a hiv victim.
      The physical problem is the easier half of AIDS.

  144. I will not be popular by saying this by Anonymous Coward · · Score: 0

    but let just stupid/poor people die.

    What kind of nature would it be if the weak were kept in the gene pool ?

    Idealism, helping your fellow humans is nice, but it's just that, idealism. There is a reason it's not called realism.

    I think Brasil does the wrong thing here, and
    should be penalized.

  145. Uninformed comments.... by ajs · · Score: 2

    I'd just like to point out the history here.

    Drug companies have been jerking around the third world for a LONG time now, and Brazil is not just an example: they will likely be the first pebble in a land-slide.

    The tactic to date has been to provide these drugs at sky-high prices in those countries so that only the very rich can affort them. Then, a G8 nation sees that Hatians can't affort AIDS drugs, so there's a funraiser or foreign aid to pay for drugs for the locals.

    This profiteering has been a major complaint of the entire third world to the UN and WTO for a long time (it's not just AIDS drugs). However, until now, no country felt that it was enough of an emergency to risk WTO/US/UN reprisals to stand up to these tactics. Brazil has offered to buy the drugs (not the people, the country), but at reasonable prices. The drug companies refused. Brazil has thus begun making their own.

    This is not theft. This is not a case of someone trying to get a free ride. This is a case of human needs vs. corporate profits.

    1. Re:Uninformed comments.... by Anonymous Coward · · Score: 0

      "This is not theft. This is not a case of someone trying to get a free ride. This is a case of human needs vs. corporate profits. "

      Oh, is that so? The costs for those drugs is about 0.0033 percent of each persons income in bazil.

      Try walk into a car chop and force them to give you a ferrari for $10 000 dollars, good luck.

    2. Re:Uninformed comments.... by SuiteSisterMary · · Score: 2

      And if you really want to, don't call it 'AIDS drug.' Call it 'BAIDS drug' which was designed by some kid in Brazil, cuz he didn't want to pay the licensing fee. It's not an AIDS drug, it's a workalike.

      --
      Vintage computer games and RPG books available. Email me if you're interested.
    3. Re:Uninformed comments.... by ajs · · Score: 2

      The costs for those drugs is about 0.0033 percent of each persons income in bazil.

      The costs of what drugs? I recall a quote from the NPR story I was listening to on this topic that the average price of the "cocktail" was about US$150/week, which translated to local currency was about 2-3 times more than the salaries of the average employed victim (I know the magnitudes here are right, but honestly could have screwed up the specifcs, see NPR for details).

      Brazil negotiated for a steep (but, not unreasonable, given the profit margins) discount if Brazil's health care bought the drugs. Of course, the drug companies wanted nothing to do with this. Why would they when they get top dollar from US charities?! Brazil was being used as a political pawn, and they're in the right, here.

    4. Re:Uninformed comments.... by ajs · · Score: 2
      Ah, found more good info on the topic:There's a lot of good information out there, but you have to look for it. American media is usually none to keen on pointing out where another government has been more vigillant in regards to human rights.
    5. Re:Uninformed comments.... by mimbleton · · Score: 1

      "Of course, the drug companies wanted nothing to do with this."

      Don't they have a right to do whatever they want ?

    6. Re:Uninformed comments.... by ajs · · Score: 2

      Sure. So does Brazil. Realistically, it's their people that have the disease, and their laws.

      My point is that the drug companies are taking the wrong side of this, morally. I'm not saying that they are not entitled to do so. Heck, they could all stop selling the drugs to anyone and stand on top of the twin towers yelling "na na!" But, I would repect them even less then.

  146. Corps are bad. by Anonymous Coward · · Score: 0

    The possibility that I won't die soon good. I say this even though I don't have any particular disease at the moment.

  147. because of this statement: by partingshot · · Score: 1

    • This should make sick every one of you that has a Free* bone in their body. ... this is IP theft, plain and simple


    I said you were unlikely to read something critical to your views because of the above statement. You may have read it, but I doubt you have fairly considered the arguments. Otherwise I doubt it would be such a black and white issue for you.
    --
    Anonymous posts are filtered.
  148. WTO treaty says Brazil IS in the right. by Anonymous Coward · · Score: 0

    Brazil is breakign no law. The treaty gives any nation the ability to disregard foreign patent laws if they invoke a national emergency, OR invoke the health of their citizens.

    What do you know... two wrongs (bad laws) DO make a right.

  149. Drugs are NOT expensive to research and develop by Anonymous Coward · · Score: 0

    Those deluded souls claiming that drugs are inherently expensive to research could do well to think again.

    There are two problems with this issue. First, the valuation for R&D costs are produced by corporates whose very justification for their prices rests upon their claims of huge up-front expenses which must be amortised over many units to deliver a profit.

    However if this were true, said companies would suffer multiple years of huge drops in profit as their research expenses totted up. Given that their recovery of costs occurs over many years, the dips in profit would be severe, even forcing them to discontinue research as continued R&D would be impossible to sustain.

    Now go take a look at some of these companies. This is not an exaggeration. Some of them can buy their own country. Do those who imagine drugs are *that* expensive to produce seriously expect us to believe that somehow these companies are sustaining continued rising profits in the face of stunningly expensive R&D?

    Of course not.

    The answer of course is that drug research merely costs time and effort. Far more money is spent by drug companies attempting to gain the necessary influence with government spheres to achieve exclusive or dominant product distribution or subsidisation than is ever spent on R&D.

    There is also the issue of research focus. Drug companies as we know them are inherently uninterested in creating solutions or 'cures' as we know them. It's simply far more profitable to manufacture substances which create a dependency in the afflicted. Anyone who believes otherwise is simply living in cloud cuckoo land.

    I think Brazil's move is timely and important. If governments do not start pushing against the massive power bases being assembled by these corporates, they will simply find themselves becoming progressively more irrelevant.

    This move is a blow against the Zaibatsus. Far from discouraging research it does in fact strike against rabid profiteering. If Roche isn't interested in Aids drug research, there are plenty of other less greedy companies that are.

    I find it hysterical that those screaming about the importance of patent protection seem to forget the most basic law of free enterprise. If there's a demand, the market will fill it.

    Don't worry guys, the sky isn't going to fall. However we may find rabid capitalism subside in the face of some humanity and common sense.
    Those who are claiming that Brazil should be prepared to pay Roche's price clearly have no idea just how bad the Brazilian situation is.

    Tell you what guys, why don't you sit back in your middle place complacency surrounded by your safe shield of Americana and pass judgement on the people who are living and dying at Roche's whim. That's a good idea. Now let's grab your mother, your daughter, your son, your brother or your uncle, fill them full of HIV and spirit them off to a land with Brazil's problems. Wonder if you'd change your tune then.

    You sit there and spit bile because you prioritise IP over human life. The real reason is much more basic. You hate the idea of someone getting something for nothing. It wounds your rabidly capitalist soul.

    Your protestations that patent protection is necessary for continued research are just so much fluff and you know it.

    I wonder if you'll ever be able to realise that you're sickening hypocrites who are dead on the inside.

    By the way. Dead people can't be consumers. Think about that.

    1. Re:Drugs are NOT expensive to research and develop by Anonymous Coward · · Score: 0

      Pfizer spent over 4 billion dollars on research and development in 2000 and 2 billion more on plants and equipment.

      In 2001 they are spending a good amount more, hard to say where it will land but 8-10 billion total is quite likely.

      Not what I would call cheap, would you?

  150. Too important to make money by Srin+Tuar · · Score: 2


    Noone is saying the companies are villains.


    Its just that most brazilians cannot afford the product. So this is money they would not be making anyway.


    So we can either force the brazilians to mortgage their asses to hell, we can force the companies to sell something below cost, or best of all we can leave them both to their own means.


    The pharmecuitical companies are not being materially harmed, dont be fooled.

    1. Re:Too important to make money by Anonymous Coward · · Score: 0

      Its just that most brazilians cannot afford the product. So this is money they would not be making anyway.

      That sounds suspiciously like the argument for piracy. Go figure.

  151. Corporate motive to not find cure. by 3seas · · Score: 1

    Hmmmm, what will happen not to the corporate motive to NOT find a cure?
    Now that this has happened?

    1. Re:Corporate motive to not find cure. by 3seas · · Score: 1

      that didn't come out right, I think. While the higher moderated posting seem to be against Brazil doing this, whos to says not finding a cure is motivated by the money for IP that doesn't cure but extends time line of patients and therefor the amount of money the patient hands the drug company for the IP drug ?
      In the US we are suppose to have this "Right to life, liberty and pursuit of happiness" but is this now to be within the constraints of corporate IP? Who really wants to cure aids?

  152. Sometimes I just can't believe... by under_score · · Score: 4, Insightful
    how fucked up the world is these days.

    Come on, the fact that this had to happen is a result of the worst possible combination of MORAL decision making. The Brazilian government is making a bad decision, but it is still the best decision under the circumstances. International law and patents are important yes, but human lives are infinitely more important. Does anyone here get that?

    And don't go thinking about any "long-term" crap about saving lives by maintaining corporate profits on research through patents. That's BS too. Governments have a very direct responsibility for the quality of their constituents lives. That's why we support (through taxation usually) research on environmentally friendly technologies, basic reasearch on health, etc. That is the long-term stuff.

    By breaking the patent on AIDS drugs, Brazil is definately keeping their long-term interests in mind:

    1. healthier population leads to more human resources
    2. healthier population leads to more grateful constituents who then focus on proactive behavior rather than complaining about their govt
    3. corporations learn that there are limits to how far they can push their greed - will start to strategize in a new conceptual framework and will certainly still be "successful" in creating value for shareholders
    4. good example set of human lives before profits for the rest of the world - allows Brazil to have an excellent international reputation allowing their citizens more access to international facilities, governments, and other processes
    1. Re:Sometimes I just can't believe... by Argy · · Score: 2

      > International law and patents are important yes, but human lives are infinitely more important. Does anyone here get that?

      There are lives at stake, and that is of great importance. But it's inaccurate frame Brazil's choice as between saving lives or letting people die. It was an issue of budget prioritization. They were spending close to $82 million annually on AIDS drugs, and felt that was too much. By comparison, they spend $12.3 billion (7.9% of their operating budget) annually on their military. So they could have rearranged their budget and still paid for the drugs. Of course many of their other budget items (and military expenses) involve live-and-death tradeoffs as well...they're in a tough position. But I believe you've oversimplified a very complex issue.

    2. Re:Sometimes I just can't believe... by bungo · · Score: 1

      By breaking the patent on AIDS drugs, Brazil is definately keeping their long-term interests in mind:

      healthier population leads to more human resources
      healthier population leads to more grateful constituents who then focus on proactive behavior rather than complaining about their govt


      That's just so true. This is in the best interests of the Brazilian politicials.

      After all the dead can't vote.

      ... well, ok, maybe they can if Mircosoft is involved.

      --
      "The best part? I became an ordained minister while not wearing pants." -- CleverNickName
    3. Re:Sometimes I just can't believe... by Anonymous Coward · · Score: 1, Interesting

      To repeat for the 800th time - this is not going to make Brazil healthier. These drugs extend the time it takes HIV/AIDS to take effect, usually in concert with a number of other treatments.
      The reality is that this will INCREASE the number of infected people there. If they did not practice safe sex previously, or did not abstain from sex outside marriage (which everyone seems to assume is impossible) - unless this drug treats AIDS and increases IQ or sexual morals - that will not change.

    4. Re:Sometimes I just can't believe... by GPS+Pilot · · Score: 1

      By breaking the patent on AIDS drugs, Brazil is definately keeping their long-term interests in mind

      Yes, there's no question that Brazil benefits from this move. But the human race as a whole suffers. It's a net loss to humanity.

      Taking the argument to extremes often helps. What if there was a drug so insanely resource-intensive to develop that the pharmaceutical firm could only hope it recover its costs by charging $1 million per daily dose. Only Billy Gates and a handfull of others could afford to take this drug. And they are the only ones who should take it. 20 years later the patent will expire and you and I will be able to benefit from it too. But if the patent hadn't been honored, nobody, at any time, would ever benefit from it because it would have never been developed!

      --
      That that is is that that that that is not is not.
    5. Re:Sometimes I just can't believe... by under_score · · Score: 2

      Actually, this is only true if you are completely stuck in a capitalistic mode where the market model is akin to a law of physics. There is always choice involved, and at some point, individuals and societies can choose greed (what you are describing) or they can choose to share. If Bill Gates/Larry Elison/etc. are the only ones who can personally afford something that is necessary to save lives, then I believe they have a moral obligation to _donate_ to the production of that something. One of the very few things I like about Gates, is that he is doing exactly this.

  153. MOD THIS UP by richieb · · Score: 1

    Even though it's an AC posting it should be modded up....

    --
    ...richie - It is a good day to code.
  154. Big Picture by NoShadow · · Score: 1

    First of all, Brazil has the biggest economy in South America, with GDP of 1.057 trillion US dollars. With a population of about 173 million people(17 percent poverty rate), that comes down to about 6000 dollars per head. Now compare this with a real poor country, say, Zimbabwe, which has 11.2 million people (60 percent poverty rate), GDP of 18 billion US dollars, 1600 dollars per head. Yes, Brazil is a poor country by US and European standards, but it's not the desparately poor country that can not afford to pay for the healthcare of its own people as some people here seem to believe.

    Second of all, according to the CNN article, the annual Brazilian budget for fighting AIDS is about 293 million dollars, and they will save about 40 Million dollars by producing the drug without license from the patent holder. Now they may sounds like big numbers, but let's compare them with something meaningful, say Brazil's defense budget, which was only 13.408 billion dollars.

    It seems to me that if they are serious about the AIDS problem and the health of their people, they have plenty of resources. All they need is the political will to use them.

    Maybe I'm just being silly, but it seems to be very shortsighted to violate International Treaties just to save 40 Million dollars, something a country like Brazil can easily afford.

  155. Not a good thing by mikethegeek · · Score: 2

    Though I agree with WHAT they are doing, I'm not in agreement with HOW they are doing it.

    Simply put, a government should not be in the business of breaking the law. That is inherantly DANGERIOUS. What is to stop them from breaking other laws to supress someone, "in the public good"?

    What Brazil should do is pass and impliment a new law that limits the scope and duration of ALL patents, and provide for mandatory non-exclusive licensing of all patents. But it should apply to ALL patents, foreign and domestic, equally and without discrimination.
    The patent holder SHOULD be compensated. But it should be reasonable. To not compensate them at all IS theft, this time on a grand government scale. That is reprehensible.
    To do it the way they are doing it is to set a dangerous legal precedent for their own citizens, and to discourage any further development of drugs and technology for their benefit.

    If a farmer grew food, only to have the government come and steal what it wants when it wants to (against the law), the farmer would be less likely to care about how much he grows, or worse, to give up the business (because he couldn't even feed his own family). This ultimately hurts both the government and the people. This is one reason why communist/collectivism has failed every time and everywhere it's been tried.

    --
    === The price of freedom is eternal vigilance
  156. Surprising... by skwirl42 · · Score: 1
    What's surprising here isn't the issue itself, it's how the moderation system has filtered out all anti-corporate sentiment...

    It seems to me, that no matter the government's true intention, that if their actions benefit their people, then corporate rights be damned.

    Ooh... poor little pharmaceutical company can't get its inane quantities of profit off a life-saving drug... well they can just go and get it off their useless drugs, like Viagra...

    These companies should be subsidizing life-saving drugs, and giving them away, simply for the priviledge of being allowed to keep their corporate charters. Companies cannot continue to exist for their own benefit, they have to be accountable to the public, and of service to the public.

    And who cares about the government, really. Castrate the corporations, and you'll see a lot more good coming out of them (governments)...

  157. If R&D is so much of the expense... by molog · · Score: 2
    Then why did Dupont, Pfizer and many other of the pharmaceuticals spend 2 times as much on marketing as they did on R&D, according to a report released July 10 by Families USA, to develop the drugs?

    If I spent a fortune researching and creating a drug, you bet I would be pissed if someone else started making my drug without my permission.

    The excuse of R&D costs is a red haring as they are spending more to market the drugs then to produce them.

    --
    So Linus, what are we going to do tonight?
    The same thing we do every night Tux. Try to take over the world!
  158. Lets arrest them all by SnarfQuest · · Score: 1

    Lets use the DMCA to arrest all the polititions in Brazil for breaking the patent (we can arrest Russians, why not others), and all of the Swiss drug companies for being capitilists (which must be illegal somewhere).

    --
    Who would win this election: Andrew Weiner vs Andrew Weiner's weiner.
  159. This is an excellent thing to cheer by FreeUser · · Score: 4, Insightful

    There are a few reasons this is a bad trend. Now they are using a public health problem as an excuse to void a valid international patent because they did not get the agreement they wanted. This plays very well in the press, "bad evil company would rather see people die than sell their stuff cheaper" instead of saying "country refuses to pay a fair price for drugs to save its own people"

    Except that three assumptions here are inaccurate:

    1) Monopolies do not yield anything remotely approaching "fair prices" without serious government intervention (e.g power companies and baby bells) and often not even then.
    2) Monopolies aren't necessary for R&D expenses to be recouped, and a reasonable profit to be made.
    3) You imply that the characterization of "bad evil company would rather see people die than sell their stuff cheaper" is unfair and inaccurate, when in fact the historical and contemporary evidence is rather strong to the contrary.

    Software patents are bad. So are every other form of patent that grants government enforced monopolies and undermines the very free market upon which our economies depend. There are other ways to finance expensive R&D besides grantintg 20 year monopolies and allowing said monopolies to extort exhorbitant prices from dying people and leaving millions of less fortunates to die (or extorting payment from their impoverished governments).

    To paraphrase another blindly pro-IP comment: This should make sick every one of you that has a Free (as in liberty) bone in their body. Ideas are not property, nor are inventions inherently something to be possessed, except as a result of arbitrary laws which have turned out to have the opposite effect as was intended, namely to slow progress rather than accelerate it, and now in the process are actively resulting in the suffering and death of millions. Frankly, I do not care if someone who thinks they have a god given right to a monopoly on an idea simply because they won the footrace to the patent office is pissed ... I imagine King George (from whome we inherited this asinine system of entitlements in the first place) was pissed when the US declared independence and you know what? That didn't make it any less right to do so.

    --
    The Future of Human Evolution: Autonomy
    1. Re:This is an excellent thing to cheer by sql*kitten · · Score: 2


      On the contrary, monopolies aren't even *possible* without government intervention. You're thinking of 'oligarchies'.


      There are other ways to finance expensive R&D besides grantintg 20 year monopolies


      Such as what?

    2. Re:This is an excellent thing to cheer by bill_kress · · Score: 1

      How about all the money that americans donated into finding a "Cure" for aids? Is that a decent alternative to granting 20 year monopolies?

      By the way, where did my money go? Shouldn't I get some of the money off these patents since I paid for some of the research?

    3. Re:This is an excellent thing to cheer by Anonymous Coward · · Score: 0

      There are people who think the law is holy, and breaking it, even if it's an unjust law, is horrifying. In my experience they're the same people who automatically bow their heads for authority when it announces itself, and consider respect to be something that is automatically granted, rather than earned. And the opportunistic scumbags amongst us will take advantage of them every time.

    4. Re:This is an excellent thing to cheer by Anonymous Coward · · Score: 0
      There are other ways to finance expensive R&D besides grantintg 20 year monopolies and allowing said monopolies to extort exhorbitant prices from dying people and leaving millions of less fortunates to die (or extorting payment from their impoverished governments).


      Name one please. It's easy to stata there are alternatives but it's not as easy to develop a well thought out plan to replace the current IP system over a set period of time. To even suggest we eliminate IP completlely is absurd. To suggest we eliminate IP and hope something better comes along is wishful thinking. To suggest an alternative goes against the Slashdot way of thinking....errr...I meant bitching and whining. You geeks need to step away from the TV and stop overdosing on too many episodes of Star Trek.
    5. Re:This is an excellent thing to cheer by Harmast · · Score: 5, Insightful
      So are every other form of patent that grants government enforced monopolies and undermines the very free market upon which our economies depend. There are other ways to finance expensive R&D besides grantintg 20 year monopolies and allowing said monopolies to extort exhorbitant prices from dying people and leaving millions of less fortunates to die (or extorting payment from their impoverished governments).


      Really?


      I would love to hear how. Outside of the government being the only source of R&D I fail to see how it would work in the drug industry.


      The standard arguement against patents is it is cheaper for me to just buy it from you than to figure out how to make it. The time to re-engineer is enough to recoup initial costs and be competitive. An inventor who does not patent does not have to open his design to the public leaving any potential competitors to complete re-engineering.


      For many industries this is arguably true. Reverse engineering complex machinery (both physical and virtual) takes time and money that are often better spent on leap-frogging ahead instead of just catching up.


      However, a drug is, in the end, a chemical. Once isolated and make into a medicinal form it is relatively simple to identify it. That is assuming that you need to.


      You don't, however, because the chemical and lots of stuff about it are public record and would be even if there was no patent. Why? FDA testing.


      The real R&D cost of drugs is not research (identifying) but development, specifically all the human and clinical testing needed. This is not a simple or short process and extends from an experimenters first idea to full scale drug tests.


      FDA regs require specific notekeeping requirements in the labs while isolating and synthesizing(see any good book on technical writing for an outine, if it does not have an experimental notebook procedures appendex or it is not a good one). This process continues throughout the process.


      Human trials are not just X people with the target disease. The first step is dose a healthy volunteer and take vitals and blood work after 15 minutes. Then an hour. Then a day later. Then try a new dose. Months or years of these human toxicity tests preceed double blind testing for affectiveness.


      At each step the drug can fail thus wasting all money to that point.


      Thus isolating the drug, which is the effort a copycat does, is the least part of drug costs. The patent is there to repay these efforts and failed ones on the way.


      Does this increase costs to the public during the patent period? Of course, because, as you point out a patent is a monopoly which does not set fair prices in the market sense (markets require multiple independent sellers and buyers to set prices). However, as the market sets fair prices it also weeds out inefficient producers. In a pure market enviroment jumping through the FDA's hoops will always be economically inefficient, thus an intelligent drug company manager will let the other companies do R&D and just copy their efforts.


      The problem comes when all drug companies get smart. In these case the patent makes sense because government is granting a limited legal exclusiveness to those who make the expenditures to statisfy a government requirement that is the largest part of the drug price.


      If you want to get rid of drug patents I would recommend getting rid of the FDA or require the FDA to pay the costs of testing.

      --
      Herb
      Again, feel free to sentence me to death if my questions annoy you. I'll come back in 5 minutes anyway. -Sythi
    6. Re:This is an excellent thing to cheer by FreeUser · · Score: 2



      Really?

      Indeed.

      I would love to hear how. Outside of the government being the only source of R&D I fail to see how it would work in the drug industry.

      See my other response. Quick options include government supported research (as you allude to), the formation of private research consortia with branding and certifications (e.g. there are free UNIX knockoffs, but only one UNIX brand which has stringent licensing and compliance requirements to use), research funded by private non-profits (think Jerry's Kids), etc.

      I really have to get back to work and cannot reply to every point in your post, but a quick, off the cuff reply to one of your points follows.

      Does this increase costs to the public during the patent period? Of course, because, as you point out a patent is a monopoly which does not set fair prices in the market sense (markets require multiple independent sellers and buyers to set prices). However, as the market sets fair prices it also weeds out inefficient producers. In a pure market enviroment jumping through the FDA's hoops will always be economically inefficient, thus an intelligent drug company manager will let the other companies do R&D and just copy their efforts.

      Patents and government sponsored entitlements in the form of 20-year monopolies are not required to level the playing field in this respect. We are already dealing with government regulation and the added cost it entails. Rather than granting 20-year monopoly entitlements, why not require that any company marketing a drug, even if it is copied from a known formula, either go through the same testing process as the "inventor" before they are licensed to sell their knockoff, buy a "license" for the certified product from the company which has already done the research and gotten the license to sell their product (probably the "inventor" at least initially), or pay a fee to the licensing agency equal to said costs to the governing agency, which fee would then be applied to further government funded or subsidized research, a portion of which could even go back to the "inventor" if entitlements really are your thing.

      Three choices in competition with one another, which level the playing field with respect to government-induced costs while avoiding monopoly entitlements and the kinds of corporate coercion such entitlements create (e.g. "we won't license this at any price!" "ok, we'll just match your cost and mimick your tests, or better yet, we'll pay the Federal Licensing Fee and help underwrite additional research in academia").

      There are undoubtably other approaches which would work as well if you give it a little thought, but for now I really must get back to work.

      --
      The Future of Human Evolution: Autonomy
    7. Re:This is an excellent thing to cheer by SilentChris · · Score: 2
      "Ideas are not property, nor are inventions inherently something to be possessed"

      I totally and wholeheartedly disagree. On the basis that most ideas are thoughts, are you saying that my thoughts are not mine, or cannot belong to me specifically? So all of my thoughts should be instantly available, even to people who I'd rather know them? Another misconception and logical fallacy of the "free".

    8. Re:This is an excellent thing to cheer by Stu+Charlton · · Score: 2, Insightful

      ": Ideas are not property, nor are inventions inherently something to be possessed, except as a result of arbitrary laws which have turned out to have the opposite effect as was intended, namely to slow progress rather than accelerate it, and now in the process are actively resulting in the suffering and death of millions. "

      You're quite right, ideas aren't property. But certain manifestations of them ARE, because society has declared them to be. If you disagree, so be it, but to suggest that IP is just naturally "wrong" and doesn't exist as a right is as naive as one can get.

      Rights are fought for, and IP right have been fought over for centuries, with the CREATORS of VALUE getting the upper hand, which is their privilege.

      It is you who must realize that society created these laws in a deliberate, systematic fashion -- not arbitrary -- and that there is centuries of legal history explaining WHY these laws exist.

      Overzelous IP laws need to be struck down, like broad patents and the DMCA. But IP law itself should not be, because as a society, we have determined it is a necessary right to promote innovation and creativity.

      --
      -Stu
    9. Re:This is an excellent thing to cheer by tmark · · Score: 2
      I would love to hear how. Outside of the government being the only source of R&D I fail to see how it would work in the drug industry.

      See my other response. Quick options include government supported research (as you allude to), the formation of private research consortia with branding and certifications (e.g. there are free UNIX knockoffs, but only one UNIX brand which has stringent licensing and compliance requirements to use), research funded by private non-profits (think Jerry's Kids), etc.


      Your first and third suggestions (not sure about the second one but it sounds crazy anyways) already happen. Yes, government sponsors research, and non-profits also fund research. Do you think research would really get done if every pharma shut down tomorrow ? Do you think Jerry's Kids and the March of Dimes and the literal hundreds of cancer-related charities and the Federal government are going to pony up the needed billions to do the research and conduct the clinical trials and bring these drugs through the FDA ? If so, WHY AREN'T THEY DOING SO NOW ?

    10. Re:This is an excellent thing to cheer by tmark · · Score: 3, Informative
      On the contrary, monopolies aren't even *possible* without government intervention. You're thinking of 'oligarchies'.


      Huh ? Monopolies ARE possible without government intervention. They certainly do NOT require government intervention - though this is often needed to BREAK monopolies.

    11. Re:This is an excellent thing to cheer by Harmast · · Score: 3, Insightful
      . Rather than granting 20-year monopoly entitlements, why not require that any company marketing a drug, even if it is copied from a known formula, either go through the same testing process as the "inventor" before they are licensed to sell their knockoff, buy a "license" for the certified product from the company which has already done the research and gotten the license to sell their product (probably the "inventor" at least initially), or pay a fee to the licensing agency equal to said costs to the governing agency, which fee would then be applied to further government funded or subsidized research, a portion of which could even go back to the "inventor" if entitlements really are your thing.


      Wow, finally someone came up with a reasonable response. Each at least addresses the real issues that make patents attractive for encouraging drug research. In fact I think one would work very well.


      That one is your second option which is a close relative to the patent, but without the ability to restrict licensing.


      While the other two are interesting I would need to think about them somemore. The key problem is that while they address paying the testing costs of drugs that make the market those are only a fraction of the drugs that entering testing.


      The sad fact is the current system requires companies to make blockbusters to recoop other costs (those huge marketing costs others cite in large part drug companies trying to make sows ears into blockbusters are increasing blockbusters) from failed drugs.


      Perhaps the best idea would be to modify one of your ideas. I think government funded research is a poor second choice because it will often lack urgency that greed provides and that gave us, among other things, powerful AIDS drugs in a little over a decade of work.


      However, what if we had the government do all the testing either on a first come, first serve, a bid basis (we'll pay x%), or maybe a profit percentage (similar to bid). Maybe charge the companies for testing for drugs that are licensed, cutting the researching company a break (to discourage all drug companies moving to a no research model) or an annual license fee (similar to a permenant government patent) until the drug is amoritized. Then the taxpayer only absorbs the costs for drugs the government won't let on the market, but companies pay for any drugs they can make a profit on.

      --
      Herb
      Again, feel free to sentence me to death if my questions annoy you. I'll come back in 5 minutes anyway. -Sythi
    12. Re:This is an excellent thing to cheer by Anonymous Coward · · Score: 0
      The standard arguement against patents is it is cheaper for me to just buy it from you than to figure out how to make it. The time to re-engineer is enough to recoup initial costs and be competitive. An inventor who does not patent does not have to open his design to the public leaving any potential competitors to complete re-engineering.

      Is it cheaper to buy a licence for one click shoppingcart than to figure it out oneself?

      A great deal of patents today are of land-grab nature - the cost of buying a licence from government-granted monopolies is much higher than coming up with one's own solutions.

      The term defensive patent is a fine illustration --- because of this artificial scarecity (only one inventor allowed), people have to act in anticipation of (man-made) disarsters.

      The original intention of patent was for society to get a bargain --- getting one invention instead of zero. But when patents are granted in areas where many solutions would pop up naturally, the bargain becomes crap --- getting one invention instead of many.

    13. Re:This is an excellent thing to cheer by Anonymous Coward · · Score: 0

      Your rethoric is missing the point. Of course your thoughts should not be ripped from your brain for everyone to share without your consent. But if you write a book about your thoughts (or build little pills based on them) and I then read that book (perhaps having bought it) then they are _my_ thoughts too. You can keep your thoughts secret if you wish, but if I get to know them (no matter how) they are mine too. The only objectable thing here could be the actions I took to get to know them like forcing you or stealing your diary. If you tell your thoughts you forfeit the right to being the sole thinker of them.

    14. Re:This is an excellent thing to cheer by Anonymous Coward · · Score: 0

      He didn't say IP-laws are naturaly wrong, only that they are not naturaly right. They are, as you say, social constructs. The are right if society as a whole deems them right (putting aside the question of how the will of "society" can be determined).
      But where you are very wrong is when you say they should not be struck down because we have determined that they are necessary. Perhaps "we" were wrong ? What was deemed right yesterday needn't be right for all time. It needs to be continualy reevaluated.

    15. Re:This is an excellent thing to cheer by AxelBoldt · · Score: 2
      I totally and wholeheartedly disagree. On the basis that most ideas are thoughts, are you saying that my thoughts are not mine, or cannot belong to me specifically? So all of my thoughts should be instantly available, even to people who I'd rather know them?



      You own your brain, and the patterns in your brain, no doubt about that. I own my brain and the patterns in my brain. I hope you grant me that.

      Patent law says: you can own the patterns in my brain if they occured first in your brain. That's absurd. You cannot own my brain. Of course, you are more than welcome to keep your ideas to yourself, but don't complain if I figure them out myself. If you tell your idea to me, then they are in my brain and therefore mine. They are also still yours, so don't complain. I didn't take anything from you.

    16. Re:This is an excellent thing to cheer by Malcontent · · Score: 2

      "WHY AREN'T THEY DOING SO NOW ?"

      The govt already pays for the great majority of the R&D in the drug industry. The drug companies pay to jump through the hoops of regulations but the govt pays for research and a bulk of testing too. Despite this though dangerous drugs still get approved only to be yanked off the shelves when people die.

      --

      War is necrophilia.

    17. Re:This is an excellent thing to cheer by aprentic · · Score: 1

      It's not as if drug companies pay for all of the FDA testing costs though.
      They get done in research studies which are largely funded by government grants, through the NIH (ie tax dollars).

  160. Patents and the amazon by bogado · · Score: 1

    I see a lot of people complaing that this is not "fair" and that the poor drug company is not going to do more research. These people are forgetting that the same drug companies send their scientists to the amazon to study "popular" medicine of the brasilian indians and then they go back and patent a drug that have been used for maybe thousands of years by the amazon indians. If this is not enougth they come back here (I happen to live in brasil) and expect us to pay a very expensive price on the same thing that our people were already using.

    A drug dealer is a criminal because he sells drugs that kill people right? Why a drug company isn't criminal when it refuses to sell drugs that saves lives, for a resonable price? This may not be illegal, but it is certanly unetical.

    Also the goverment of Brasil have asked the company to reduce the price. They refused to do so. The goverment then gave the "go ahead" on the production of this drug.

    --
    []'s Victor Bogado da Silva Lins

    ^[:wq

  161. Drugs... by Anonymous Coward · · Score: 0

    I support both the drug company and the people.

    The simple fact is that drugs cost TOO MUCH. Yes, the company needs to turn a profit and to recoup R&D expenses, but x00% profits are not necessary for this. To my fellow americans....how many of you take claratin? It's about $70 for a months worth of the drug. If you go across the border into canada, you can get the SAME drug over the counter.....and how much does it cost? Last month when I bought some it was on special....2 boxes (essentialy 2 months) for the price of one.....which was $18 Canadian. The drug isn't any cheaper to make in Canada, so why the price difference?

    The drug companies to need to get a clue....yes, make a profit, yes pay for R&D, but keep the drug prices within reach for those who need it.

    On a side note....to claim that a drug company can't make a profit at the price the generic drugs are being sold at is crazy.....if that were the case, then the generic companies (i'm not talking about state run production) would go out of business.....and they aren't. Just something to think about.

  162. All countries... by Anonymous Coward · · Score: 0, Interesting

    If all countries did this...

    Corporations would have no incentive to research it. Of course, they don't research any of this now either, so there's no loss. Don't forget, all this "corporate research" is basically patenting the work of grad students at universities who have received federal grants.

    What incentive would remain? The ability to manufacture a product in large quantities at your economies-of-scale plant, and sell it at a guaranteed 10%-15% profit. The consistent ability to produce millions of any thing at 100%+ profit margins is indicative of a monopoly. Note thats any THING, not just anything. That type of monopoly can only exist due to artificial scarcity, such as from patents.

    The WTO treaty specified that any country can disregard patent laws in issues relating to the health of its citizens, so Rouche can go shove it.
    However much this provision may be abused in the future [free dreamcast games are critical to the long term health of our society's hand-eye coordination development ;), THIS is not an abuse.

    Viagra for example, sells at an 11,000% profit margin on manufacturing cost.

  163. The Power of Goverment by exotrip · · Score: 1

    Why not have world goverments doing drug research? It would be beneficial to the people, it would be funded by tax payers, and the medicine would be naturally less expensive, because there are no patents (since it's our goverment and we are paying for it, they don't own it-- we do). They already regulate drug safety. Let's take it a step farther and have them make the drugs.

    Just a thought

  164. Do you mean by Srin+Tuar · · Score: 2

    If we don't provide some sort of protection, there won't be any incentive for people to invest in the first place. Would Roche have devoted the money necessary to Market this drug if anyone who is capable of manufacturing it could do so? Hell no. This drug has saved lives (well, extended them, at least -- which is all any drug can really do). This drug would probably not exist if it weren't for patents. QED...


    The actual development of new drugs is highly government funded. So these patents are a very insidiuos form of corporate welfare.


    Pharmecuetical companies do invest money in marketing, patenting, middle managment, production, etc. This is mostly low risk.


    The profit motive is excellent for physical production. But it breaks down with ideas, and has the opposite effect there.

    1. Re:Do you mean by syates21 · · Score: 1
      The actual development of new drugs is highly government funded. So these patents are a very insidiuos form of corporate welfare

      Please cite one example where the government has funded the development of a drug. I'm not talking about some basic research that eventually, years later, leads to a developed drug, but the actual development (i.e. clinical trial process) of the drug itself.

  165. Companies dont do discovery research... by Anonymous Coward · · Score: 0

    Companies dont do discovery research... Governements and academics do. The gov't generally is the one funding the reseach done at the university level.

    Corporations merely take that tax payer funded public research and apply patents to a process for mass producing it. Those patents are what gives them a monopoly, not research they did on their own.

    1. Re:Companies dont do discovery research... by DrZZ · · Score: 2, Informative

      That certainly hasn't been my experience. Working in drug discovery for over 20 years (mostly for government) I would say that the majority of actual drug discovery efforts (as opposed to more basic research in biology of diseases) is done by the drug companies themselves. Also look where the market is for novel drug discovery techniques. There are many such techniques that have strong roots in acdemic labs, but the hard work of turning these interesting ideas into useful tools is funded either directly by the drug companies or indirectly because the drug companies are the only places that will pay big bucks for the finished product.

  166. AIDS Cure Found! by 3seas · · Score: 1

    OOPS! Looks like Roche is gonna pull a lawsuit against the research team that came up with the cure, for making their (Roache) IP worthless.

  167. I gotta take Brazil's side on this one by JahToasted · · Score: 1

    Roche is basically saying to Brazil "pay what we want you to pay or your people die."
    Brazil says "be more reasonable with the price of these drugs or we violate the patent and produce the drugs ourselves."
    Who is worse?
    The article doesn't say that Brazil is unwilling to pay anything, just that they wanted Roche to be reasonable. The article states the Brazil is complying with agreements with other pharmaceuticals. It seems to me Brazil is willing to compensate the pharmaceuticals as long as they are being reasonable.
    A lot of people here are saying this will make the pharmaceuticals stop all research. What will really happen is the pharmaceuticals will be more reasonable when dealing with third world nations which just can't pay outrageous prices for drugs.
    Excuse me for not feeling sorry for pharmaceutical giants...

  168. Newsflash! Slashdot readers readily hand over thei by Queer+Boy · · Score: 1
    Apparently BigBusiness (tm) has won out over Social Justice. I found it interesting that the highest moderation points went to posters stating (basically) that drug companies making money is more important than saving lives.

    Fascinating statements coming from an Open Source community. "If there's no money in it, there's no reason to do it."

    "Put your foot in your mouth enough times and eventually you're going to kick some teeth out."

    --
    Not since Marie-Antoinette played milkmaid has looking simple and honest been so fake and complicated.
  169. Equipment costs... by Anonymous Coward · · Score: 0

    Brazil has to buy the equipment too ya know. They're not actually hijacking corporations frigates at sea. They have to buy all the physical equipment as well, so your "lab costs" are a red herring.

    Companies dont do discovery research... Governements and academics do. The gov't generally is the one funding the reseach done at the university level.

    Corporations merely take that tax payer funded public research and apply patents to a process for mass producing it. Those patents are what gives them a monopoly, not research they did on their own.

  170. Congratulations to Brazil. by Brian+TNB · · Score: 1

    If the looneytarians in the crowd will stop screaming bloody murder for five minutes, maybe they'd recognize that this is also a matter of sovereignty. Brazil is one of many countries where AIDS is killing people like the bubonic plague did before the Enlightenment. It is a time of public health emergency, and it is not up to Roche, the US, or anybody else to decide for them. People are dying, and all these arguments about long-term damage are bullshit.

    --
    Wise man say, choose your enemies carefully, for you will become like them...
  171. human life IP in the short run by infoflux · · Score: 1

    I've seen a number of posts stating why violating IP protections with medical r&d is bad in terms of halting future development. The point that people miss is that the drug companies have made a significant amount of money selling AIDS drugs in the US and in other countries that can afford them. I'm not sure if they've recovered their R&D costs entirely, but its a pretty good possibility that they have.



    The important distinction to make is that Brazil isn't making their own AIDS drugs because they don't WANT to pay for the legit ones. They are doing so because they CAN'T afford the insanely expensive medications. In reality, I don't think that the drug companies are losing much money because countries like Brazil couldn't afford to buy the drugs at market price anyway. Its not a question of name brand AIDS drugs or cheaper homegrown ones. Its a question of homegrown AIDS drugs or no AIDS drugs.



    This is where I think the idea of eminent domain and IP are really important. The drug companies have done a service to the world by creating AIDS drugs that save lives and help slow the epidemic in developing nations. Unfortunately, they are profit-making ventures, and producing those drugs cost money. I agree that they should be compensated for their efforts and expense. However, the first priority should be saving human lives. We should worry about distributing these absoutely neccessary drugs where they are needed first, and about paying the drug companies later. Still, in order to continue development, we need to somehow ensure that the drug companies get compensated. This is where organizations such as the IMF, WTO, UN, and other governmental organizations should foot the bill for the R&D. I think they should develop some policy for seizing the IP of the companies and fairly compensating them for it. At the same time, they need to ensure that it is clearly defined when a country can violate IP. If a country can afford to buy the drugs at fair market prices, they should. Similarly, if a country is financially mismanaged, these organizations need to help these countries develop more stable governments with more sound (and less corrupt) fiscal practices so that they wil some day be able to participate in global markets. Simply burrying countries deeper and deeper in debt (as is the current practice of the IMF) doesn't do anything for the developing nations. The drug companies might not make as much money as they would like, but this way they won't lose money. It might not be totally fair for the companies, but in the end, human life is more important than IP.



    As and addendum, some hard asses that have posted are suggesting that the AIDS epidemic is the fault of individuals who participate in unsafe behavior. While this is certainly the case in some instances, particularly given the lack of education in the third world, it is important to note that most of the developing nations with AIDS epidemics have huge pediatric AIDS problems as well. Certainly young children who contract AIDS from their mothers are not responsible for their terrible disease. I think that the interests of children alone provide a good enough warrant for Brazil's actions.

  172. R&D, Marketing, Profit. by vovin · · Score: 1

    Drug companies make back the R&D on a drug in 3 - 6 months (more often the 3). *All* the rest of the expenses are in marketing ... it's all profit.

    The excessive profits of the pharmaceutical industry are protected on one side by the cost of bringing a drug to market (FDA) which reduces competition. On the other side drugs are also patented, which reduces competition.

    On the other hand naturally occuring compounds that already exist in nature which may/may not have medicinal value: Asprin, opium, penicillin, caffeine, etc. Would not be produced in todays market, they would never be able to make claims of medicinal value because nobody would fund the FDA trials!

    On the other hand the pharmaceutical industry will happily create copy-cat versions of those same drugs which *are* patentable, but often (not aware of any which don't) have mild-to-severe side affects which were not present in the naturally occuring compounds.

    *I* think that the government should prop up the University system and Non-profit organizations and allow them to bring non patententable drugs to through FDA trials. This can be done with either grants, or via a not-a-patent-patent that expires when the drug has made it's ROI. I believe that grants would be the preferrable method (more oversight of grant money, as well as grant money only given for research that shows a reasonable liklyhood of being successful. This would improve the state of competition within the industry, as well as our health!.

  173. If I was a drug company CEO..... by duffbeer703 · · Score: 2

    I wouldn't be making any new AIDS drugs.

    Scientists don't work for free. It may sound great to say "Fuck patents, lets take care of people" at first, until you think about it.

    Drug companies will stop sending important drugs to places that flaunt their disregard of the law like Brazil. A few AIDS patients may live a little longer, but alot of new antibiotics & other drugs will never make it to Brazil.

    --
    Conformity is the jailer of freedom and enemy of growth. -JFK
  174. did you mean "say bye bye to any new software"? by ViVeLaMe · · Score: 1

    What's so different between R&D'ing software, and then patenting it to protect it, to be able to sell it, and R&D'ing a drug, so you can patent it, and sell it?


    Why would anyone bother coding if they can't patent their nice GUI, why bother to do the On Click Buy if the next guy can come and steal it from you?


    Ah, you mean you're against software patents, probably because those prevents you from finding a free (as in beer) replacement for this MS shit.. But you don't care about drugs patents, because you'll never be ill, or you'll always be rich enough to pay for you drugs.. Let the poor bastard die, they're useless scum anyway.

    did i mention i really don't want to get to know you? :-P

    --
    i had a sig, once..
    1. Re:did you mean "say bye bye to any new software"? by NineNine · · Score: 1

      Actually, I'm in favor of software copyrights, too. There are plenty of apps that just wouldn't ever be developed without some company being able to earn a profit from it. The ONLY reason that people develop OSS is because A.It's fun for some people and B.There is a critical mass of people with this skill. However, I sincerly doubt that we'll ever see the day when chemists and doctors spend millions on equipment, their time, etc. to just develop AIDS drugs for fun in their basement. There's a big difference between software and drugs, but yes, I also believe there's a place for software copyrights. Also consider this. A drug is a drug. A formula is set. There's no advantage to buying a name brand drug over a generic. The generic can be an EXACT copy of the original. There's no advantage to buying the more expensive one from the inventors of that drug. Software? There's a big difference between Windows and Linux, for example. Each have their plusses and minuses. They're not exact replacements for each other. So while Roche may not have any incentive to develop new AIDS drugs if companies are going to steal them, MS will still have incentive to create software because people will still buy it, even if there's a competitor, because that competitor isn't a perfect replacement.

    2. Re:did you mean "say bye bye to any new software"? by ViVeLaMe · · Score: 1

      well, if there is no more software patents, i guess one could do the exact same Win95, same GUI, hey, whynot same CD, just rip off the registering part, and *there*, your freewin95.
      Why bother coding a win98? in the next 2 hours, it'll be ripped off and available on the internet. In fact, even with the formula, it's not that simple to produce a drug. You have to build the factory, to engineer the processes, because most of the time, those are less than obvious..So drugs are still better protected with no patents than software. YOU can't do your own copy..
      I'm not against patents either, see, but i'm pretty much against stupid use of patents.
      I mean, ok, let rich countries pay the retail price. then let those that can't afford it copy it and do their own, if u can't provide them at a cost they can afford..We're not talking about luxuries, here, but *vital* stuff. It's no hijacking of cable TV, it's *fighting for your fucking life*, that's not quite the same. Just like guns are allowed in most of the US, while illegal nearly everywhere else, for, you know, self-defense, you can get to kill someone (at least, you're allowed to buy stuff designed just for this), well, brazilians, to save their life, had to steal the drug. too bad for Roche, but, hey, things happen..

      --
      i had a sig, once..
    3. Re:did you mean "say bye bye to any new software"? by clare-ents · · Score: 2

      "
      What's so different between R&D'ing software, and then patenting it to protect it, to be able to sell it, and R&D'ing a drug, so you can patent it, and sell it?
      "

      Chemical patents generally read something along the lines of

      $company has discovered $big-chemical-structure which is known to inhibit $disease.

      Software patents read something along the lines of

      $company has discovered the idea of a cure for $disease

      A chemical patent covers the only method & implementation. A software patent covers the idea behind. The method is already protected via copyright.

      The other reason is medical reserach doesn't have a monopolistic tendancy in the same way that software does.

      --
      Only two things are infinite, the universe and human stupidity, and I'm not sure about the former. (Einstein)
  175. The goose with the golden egg by baalz · · Score: 1

    1) Drug companies obviously make too much money if they spend it on advertising and lobbying. All the good, hardworking companies cut such things out to be more competitive.

    2) If we take away the profit in developing new drugs, we will net more lives saved. We don't need the billions spent by evil investors primarily motivated by money. New drugs will be developed fast enough through good will that lives will not be lost which could have been saved by faster/better research. This certainly won't compound over the next hundred+ years as disease and sickness evolve, I mean heck, everyone knows evolution is a screwy theory. We probably won't even need any new research.

    3) Nationalization of private assets for the good of the whole is a great idea. I mean, if you can't trust your government, who can you trust?

  176. Thats not true... by Anonymous Coward · · Score: 0

    First off, 33% of the $10,000USD annual PER PERSON AIDS drug cocktail isn't going to work in a country where the annual salary is less than $3,333, and over there the pay usually a nickel an hour.

    FYI, It costs about $200USD to make the pills.

    As for the red herring of "giving them away for free" that referred to ONE BATCH of a drug that required refrigeration - something not available in most of the country it was offered too. The company refused to say what it would charge for the next years supply. DOn't forget... these are TREATMENT drugs... not cures. Treatments drugs need to be taken for the rest of the person's life... whether its six months til they die or 60 year.

    Besides...

    Companies dont do discovery research... Governements and academics do. The gov't generally is the one funding the reseach done at the university level.

    Corporations merely take that tax payer funded public research and apply patents to a process for mass producing it. Those patents are what gives them a monopoly, not research they did on their own.

  177. don't feel sorry for the biomedical companies by maddogsparky · · Score: 2
    I don't. Not since they have become the new darlings of Wall street due to their record profits after the burst of the .com bubble. I don't mind paying a fair price, but they got too greedy and have potentially lost it all.

    --
    science is a religion
  178. Lets look at the numbers here by Anonymous Coward · · Score: 0

    $82 million is 28% of the AIDS budget of Brazil. This implies Brazil spends $293 million on AIDS.

    (I am going to assume in an US centric way that they mean dollars and not reals since I don't want to look up the exchange rate. The article wasn't clear on the point.)

    They claim they will save 40% of the drug costs which implies they are either going to let the locals make some cash or the markup Roche is charging is around 66%. Not exactly an obscene percentage on a successful drug that has to carry the freight of every failed drug they researched.

    A 40% savings is $33 million in a country with 175 million people and a GDP of $1,000,000,000,000 according to http://www.factmonster.com/ipka/A0107357.html. That's right. One trillion GDP.

    So in order to save 40% of 28% of their entire AIDS budget of $293 million they are going to flout the law and cloak themselves in righteousness to boot.

    These guys spend 0.03% of their GDP on AIDS. To actually pay for this medicine they would have to spend 0.033% of their GDP fighting AIDS.

    I think respecting IP rights is probably worth 3 one-thousandths of one percent of your GDP.

    CAL

    1. Re:Lets look at the numbers here by codeforprofit2 · · Score: 1

      I think they simply want what others have invested huge $$$ in for free. It's just as simple as that.

      Mod the parent up, very informative.

  179. Bad Idea by muffen · · Score: 1

    I dont like the fact that some people (countries in this case) can do whatever they feel like breaking any rules they see fit.
    The patent is there to protect intellectual property. I think it's time to start seeing the drugcompanies for what they are... companies. If people/countries can simply ignore patents, then drugcompanies will simply stop researching new medications.

    The Brazil government should be sued for this, and Roche should win. I agree that people's lifes are important, but we have to understand that the rules exist because they have to.

    In a perfect world, all medication should be free and no child should go hungry. Sounds really good, but we all know that this is not reality. Unfortunately, we will not reach the perfect world by ignoring rules. We will just end up making it worse. If the Brazil government can ignore patents, why can't the US do the same? The entire Africa is poor and they all have AIDS problems, why can't they ignore every single patent there is for AIDS medication?
    We can clearly see here that this is getting out of hand. This cannot and should not be allowed!!

    If the Brazil government will get away with this, I should be able to copy MP3's legally. My reasoning for this?
    Well, alot of artists I listen to have drugproblems and/or alcohol problems. The ones that don't... well... they are artists... so they will soon enough. By not buying their CD's and thereby not giving them any money, I'm saving their lives.

  180. Developing a cure IS profitable. by Manax · · Score: 1
    ... for the one who gets there first.

    If multiple companies are creating these drugs, the first one to create a successful cure will crush their competition and their pitful "treatments", and be able to charge more for the cure than the other forms of treatment.

    As long as there is competition, developing a cure is a likely.

    --
    "Why should I be content to simply live in this world, when I, as a human being, can CREATE it?" - Oertel
    1. Re:Developing a cure IS profitable. by clare-ents · · Score: 2

      "
      As long as there is competition, developing a cure is a likely.
      "

      But releasing it isn't.

      If you are a pharmaceutical company in possession of a treatment for $disease and you discover a cure for $disease it's in your interests not to release the cure until your patent on the treatment expires or another company discovers a cure.

      Cures are not profitable compared to treatments, cures can only be sold once, treatments many times.

      --
      Only two things are infinite, the universe and human stupidity, and I'm not sure about the former. (Einstein)
    2. Re:Developing a cure IS profitable. by Manax · · Score: 1
      I disagree. If a company develops it's cure, it should release it as soon as possible, so that it doesn't give time to other companies to develop their OWN cure, which would cut into their market.

      "Cures" in this case are probably treatments which can cure the disease, which isn't to say that it cannot recur. Just look at something treatable like chlymidia or syphilis. Both curable, but still present in world. More than likely, a company will be able to sell a cure very well for the duration of the patent.

      --
      "Why should I be content to simply live in this world, when I, as a human being, can CREATE it?" - Oertel
  181. Libertarian-free as in Intellectual Property?!? by A+nonymous+Coward · · Score: 2

    Somehow the idea of government enforced intellectual property doesn't strike me as quite the libertarian philosophy. Maybe you have decided to overlook that patents and copyrights were deemed a necessary evil only for limited periods and expressly against the wish of Thomas Jefferson and other founding fathers.

    IP is theft from the people. It was accepted by some of the founding fathers as an exception to the first amendment (free speech). It was not, and is not, universally accepted as proper.

    The theory that anything Intellectual can be Property is a far cry from naturally scarce physical goods being Property.

    If you want to bring up that old chestnut about pharmaceuticals needing to recover their R&D costs, why not also mention that the typical marketing costs of new drugs are higher than the R&D costs? Surely any truly marvelous new drug would not need such exorbitant marketing.

    Why not also wonder at the exorbitant tests necessitated by that non-libertarian entity otherwise known as the FDA, somewhat in self defense against ridiculous lawsuits? Surely there's a lot of money to be saved here in exchange for the small loss that whiners would have to accept some of the risk that a potential life-saving drug might have side effects.

    Why not also wonder at those pharmaceuticals who stretch out the patent lifetime with bogus lawsuits against the generic manufacturers?

    Why not also wonder at those pharmaceuticals who dream up trivial new uses for those drugs so they can delay the entry of generic equivalents?

  182. An idea to deal with this problem. by Anonymous Coward · · Score: 0

    Here's an idea. I think patents on chemicals (drugs) are ok, even if I have problems with patents on pure thought (math/software).

    What is needed is a compulsory license that lets poor nations produce patented drugs at a rate proportional to their average (or median to keep a few rich people from skewing this) income compared to the rates an industrialized nation would pay. This should probably be scaled up by a factor of 2 or 3 or so, just to keep many nations near the top of the economic ladder paying for the drugs at full price.

    It would also give large corporations an incentive to make the rest of the world richer. :) Imagine that.

  183. All that *extra* money by Rika · · Score: 1

    Okay, so, Brazil gives IP rights the finger, steals the AIDS drug, and saves 40% of its money, correct? Controversy aside (I think what they're doing is wrong and an agreement should have been reached, but that's not my question), what happens to that 40%? If Brazil is as 'humanitarian' as I suppose it is trying to be with this patent violation, the money would go to health (and general) education, condom distribution, and further research into better AIDS medication. That would be an ideal world. My bet is that it goes to something completely non-related. Like, oh, upgrading the official car fleet, or redecorating the AIDS office headquarters. I want to know if Brazil is doing this to really help people, or just save a buck and get its name in the paper.

    --
    Never express yourself more clearly than you think ~Neils Bohr
    1. Re:All that *extra* money by night_flyer · · Score: 1

      back up a second here... they save 40%, but what if (and this is a BIG possibility concidering we are talking about Brazil here) they didnt HAVE the extra 40% to spend without cutting off other programs?

      --


      Thanks to file sharing, I purchase more CDs
      Thanks to the RIAA, I buy them used...
  184. OpenHyst... by Anonymous Coward · · Score: 0

    Sounds great. People die in FDA approved drugs too. At least under this model we'd know why, and be open honest and up front about it. It also sounds like side effects are eliminated pretty quickly under your model. People allergic to peanuts already know to check the label anyway. Their doctor probably knows too. and since DOCTORS are prescribing the drug, a curious hackerish one would have pointed out the mercury in the thermalase(sp?) compound used to keep the drug preserved. You can fix that in the next version, and we all get healthier for pennies on the $100.

  185. Incentive by Talsin · · Score: 1

    All I hear from people is that drug companies wont have the incentive anymore to make drugs if Brazil does this. Here is an extreme simplification as I see it...

    1. Damn the patents, people are suffering and dieng. Do what we can to help and do it now before more die.

    2. Respect the, and I dont disagree here, rightful patent of the company that researched and developed this drug and let potential untold masses suffer and die while we negotiate fair terms.

    Maybe I have it wrong, and I have a very low opinion of where the collective world is headed but lets give it the benefit of the doubt and pool our resources to battle this plaque with every resource we have, not bicker and fight like greedy children.

    Incentive? How about watching someone you love die from this horrible disease because they were too poor to pay for the medicine that might have helped them live.

    How much better could this world be but for the loss of those might not have had to die?

    Curtis Myers

  186. It ain't all good... by main() · · Score: 1

    Is it not possible that this sort of patent infringement could have the undesirable effect of dissuading companies from disclosing inventions for patent review?

    Income from patents which cure disease and ease suffering in some of the poorest parts of the world is nothing short of blood money.

    At least the Brazilian government had the option of infringing on this patent. In the not too distant future, maybe even this will be denied by money-sucking corporations intent upon hoarding their intellectual property to the detriment of those for whom it is most needed.</anti-capitalism>

    Si

    --
    "things... can only get better..." - some pop song

  187. Way to go Brazil by NitsujTPU · · Score: 1

    While I agree that the people who develop such drugs deserve compensation, not a single life should be lost in the name of a buck.

  188. Re:India, Brazil, China... half the planet already by Anonymous Coward · · Score: 0

    Interesting point, but exactly how many commercials have you seen that advertise an AIDS medicine?

  189. Re:Newsflash! Slashdot readers readily hand over t by codeforprofit2 · · Score: 1

    Haven't you noticed that the open source companies is-not-doing-so-great? Filing for bancruptsy is a bad thing you know.

    This is not at all a issue about money over lives. It's about do we want more drugs in the future or don't we?

  190. typical business bashing by Anonymous Coward · · Score: 0

    i guess "Big Pharma" must be stopped at all costs!! they are greedy bastards!!

    well not really. Brazil is more concerned about saving money than actually saving lives. Drug companies do 500x more to save lives than any government. But they do need money to support and fund research, as well as make a profit.

    1. Re:typical business bashing by Kryptonomic · · Score: 1
      Brazil is more concerned about saving money than actually saving lives.

      Oh, I don't think so.

      a) Brazil really cannot afford the cost of medication for such a large number of their citizens.
      b) They know the formula for effective medication and they can produce the drug.
      c) They are prepared to accept the PR damage caused by infringing an international patent.

      Solution: manufacture the drug.

      I think that's only fair. The company is at fault for not being able to provide their drug at a reasonable cost.

      Unlike you fearmongers seem to imply, the drug development won't stop even if the companies would go under (which they won't). People get sick and drugs are always needed. If the companies stop producing drugs (which would be economically insane), governments will through publically funded university research.

  191. R&D costs... by Anonymous Coward · · Score: 0

    Companies dont do discovery research... Governements and academics do. The gov't generally is the one funding the reseach done at the university level.

    Corporations merely take that tax payer funded public research and apply patents to a process for mass producing it. Those patents are what gives them a monopoly, not research they did on their own.

    EXAMPLE: (ripped from post#2208214)

    Here at the University of Minnesota - Twin Cities, they helped to develop and owns some of the patents for the AIDS drug Ziagen, which was then licensed to GlaxoSmithKline. This is one of the drugs involved in the patent suit in South Africa earlier ths year.

  192. It's About Time by Sharadin · · Score: 1

    It's about time someone did this; I mean, what is the point in follwing rules when they are made by braindead Neanderthals in the first place.

    Just wait until Nanotechnology comes into the picture...there won't be ANY intellectual property to whine about. This is definitely a step in the right direction.

    Now if someone would come up with a way to get rid of the monetary system, that would be something to really rejoice over.

    1. Re:It's About Time by Mad+Marlin · · Score: 1
      Just wait until Nanotechnology comes into the picture...there won't be ANY intellectual property to whine about.

      You apparently do not realise that every piece of nanotechnology will be patented. Therefore, it wil not get rid of any patents. Why is this? Because all of the research into nanotech is being performed by large companies being run by ``braindead Neanderthals'' who know a lot more than you do, but are willing to help you and the rest of humanity out with their knowledge, just in exchange for a big enough salary so that they can buy a new Lexus every year or two. Think about it, it is a pretty fair deal: You get to not die of AIDS, and they get a new Lexus. They don't need to spend their time doing research, and even if they do, they don't need to even tell you that it exists. They are just being nice.

    2. Re:It's About Time by Sharadin · · Score: 1

      Well, considering AIDS was manmade to begin with, no one deserves to profit from it.

  193. NPR?!? by Anonymous Coward · · Score: 0
    BWAHAHAHA!!!

    Well, then, if you heard it on National Proletariat Radio, it must be true!

  194. Equal protection under *which* law? by Lemmy+Caution · · Score: 2
    No, profits aren't a right. Equal protection under the law is a right. The issue here is that these companies invested billions in research and testing on the expectation that if they found something useful, they could sell it under the same laws that apply to everyone else.

    Since countries are signatories to IP laws and can sign out of them, your plaint begs the question of whose laws apply. The pharmaceutical companies develop drugs based on US and European laws for the US and European markets. They have no right to dictate the laws of other countries - if Brazil passes a law that gives Brazilians the right to reverse-engineer any drugs they need to, perhaps they will face trade sanctions when they try to export them, but they certainly have every right to pass that law.

  195. Chris Rock by Ratteau · · Score: 1

    "There aint no money in a cure!!! They just want you to be able to live with it. Twenty years from now, youll be calling into work 'no, I cant make it in today, my AIDS is acting up'"

  196. AIDS drugs are expensive for a good reason by Mad+Marlin · · Score: 1

    All of the drugs that are currently being used to treat AIDS are expensive, but for a very good reason. The expensive part about the drug indrustry is not (usually) the making of the drug, but rather all the years of research that go into figuring out which drug to make. That company has probably been devoting research into this for 10-15 years, and just now have a halfway decent solution, which is still far from an actual cure. To find an actual cure may take another 10-15 years, or even longer, and that requires a whole lot more money. Where do you think this money comes from? Certianly not the government of Brazil.

  197. Anyone remember Jonas Salk? by EXTomar · · Score: 2

    Hurm...what really bothers me is that a bunch of people are saying "This is bad! Where is the modivation for pharma company to do R&D now?!"

    I am way to young to know what polio was. My grandparents tell me it was a pretty scary thing but thanks to one guy and his research team polio is very preventable and contained. I was under the impression Jonas Salk did his research into polio vacines not because there was money to be had but because polio was a nasty crippling disease. I could be wrong though...

    Is it too much to expect people to look in to the cure for AIDS because they think the world would be a better place without such a horrible thing around? Do people really have that much faith in big company's bottom lines to drive R&D to cure AIDS and other nasty disease?

  198. Re:FUCK PEOPLE WITH AIDS by Kenyaman · · Score: 1

    It might not be in the 'States and/or Europe, but in Africa it certainly is (and I gather in South America as well). I've heard estimates that over 70% of the people living in Nairobi are infected. President Moi even suggested that Kenyans should simply abstain from sex altogether to try and get this under control.

  199. This is a FSCK'ng trend to cheer !: by ViVeLaMe · · Score: 1

    some random thoughts.
    - Are u SURE that Brasil (how rich a country we have there, indeed..) can afford to pay the "fair" price for the drug? obviously you haven't researched a bit. try for example http://www.globalexchange.org/campaigns/brazil/eco nomy/DebtTribunal.html , and get a clue.
    - now we can be allowed to think that Brazil can't pay for *grossly overpriced* drugs, what were they supposed to do? Sit down and die? or grab it and run? Maybe ask nicely? they did, they were told "no".
    - "2. Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment. (some diseases are more prevalent in certain areas of the world - that is an obvious statement)."
    Hey you know what?
    companies DON'T develop regional treatments. NO big company research, say, Malaria. So i guess it can't get worse, uh?

    "Apparently people are willing to allow those with the guns to do it, and not realize its the first step to losing their own rights." yup, let's all listen carefully to those drugs giants saying: you didn't pay, you're gonna die. and be nice with them, they didn't really mean it, did they?

    --
    i had a sig, once..
  200. WRONG by Anonymous Coward · · Score: 0

    I don't care how much it costs to make a drug (research and all), if you can save (or extend) just one human life by breaking a patent, just one life, you are totally justified in breaking the patent


    And then when Roche decides to go out of business, then what? What about the thousands or millions of lives lost that would have been saved by future revolutionary drugs that they may have gotten had Roche developed it in the future?



    Such short-sightedness is what is killing this country, and apparently now, the world.



    Also, RTFA's and see what Brazil was paying as opposed to everyone else. They werent being price "guaged" (or gouged if you speak English).



    Rants are fine. Just be sure your soapbox isnt an empty cardbord box.

  201. Sounds like FUD by Dirk+Pitt · · Score: 1


    Brothers and sisters, AIDS is our problem. It makes the bubonic plague look like a bad case of hiccups.



    You sound like someone who was afraid to sit next to Ryan White during the ignorant 80s. Last time I checked, the Plague was caused by Yersinia pestis, and spread through fleas, coughs, sneezes, and other easily communicated methods. AIDS, to the best of my knowledge, can only be spread through sexual transmission and direct exposure to infected blood; it is significantly more difficult to acquire. This is why a majority of the population still treats this disease with relative apathy; they avoid it by the very nature of their lifestyles.


    This isn't to say that I think situations like that of Africa and many other third-world countries doesn't need to be solved _now_. There is a difficult road to pave by grassroots education campaigns, volunteering, and the like. The easy, unfair way to defeat AIDS is by hijacking the pharms, a solution that may come back to haunt these would-be heroes.


    I would answer your fireman analogy by saying that if enough people purposely light their curtains on fire just to see them glow, the local counsel will disband the fire department before there's even a chance to steal one truck.

  202. actually.... by _avs_007 · · Score: 1

    If you are born from a mother with aids, how is that the baby's fault?

    If you are car-jacked, and the guy, sticks a needle in your arm, how is that your fault? (Yes, its happened before)

    If you are a nurse, and you get pricked with a contaminated needle, how is that your fault?

    If you get a blood transfusion from contaminated blood, how is that your fault? (And if you think that 100% of the blood is safe, and the tests are fool-proof, then, well... good luck to you)

    If you take precautions and use a condom, how is that your fault? What, you think its 100% effective? Oh, you should've known? What if the other person doesn't know either? Or what if they didn't tell you? How is that your fault?

    Also, last time I checked, there is no such thing as a "world government", hence laws in other countries do not apply to other countries. Though, governments would like to think otherwise...ie If something is trademarked in USA, and a company in Timbaktu is using it, do you think they give a rip? Just look at Nike... They were not allowed to provide uniforms/equipment in the 1992 Summer Olympics because either Nike or the swoosh, (I forget which), is already a trademark in Spain. You think that will make Phil Knight change the name of the company or logo, in the USA? Heeeeeeeeell no!

    etc etc etc

    1. Re:actually.... by Anonymous Coward · · Score: 0

      If you take precautions and use a condom, how is that your fault? What, you think its 100% effective? Oh, you should've known? What if the other person doesn't know either? Or what if they didn't tell you? How is that your fault?

      That one is easy. If you don't know a person well enough to know they don't have AIDS AND wouldn't lie to you about it, you should be keeping little willie in your pants. Sorry guys, but it's true. If you want to screw random people off the street then you need to live with the consequences.

    2. Re:actually.... by AndyChrist · · Score: 1

      Unless it really is literally a random person off the street, someone who can leave, never to be found again, and easily escape all retribution...why would anyone be stupid enough to lie about having AIDS, and get someone infected?

      Seriously, if I knew my life was going to be seriously impacted, probably severely shortened, and possibly not worth living anymore, I would make sure that that person died a more horrible death than AIDS could ever provide.

      Am I in the minority here?

    3. Re:actually.... by Anonymous Coward · · Score: 0

      You know, its easy for you to say this anonymously in an online forum.

      Try saying that to someone's face or in a public place. If you did it to me, I'd beat you down into a bloody heap and hand you over to an HIV carrying bubba for your hot beef injection.

  203. You are wrong. by Anonymous Coward · · Score: 0

    Since I have inside facts regarding this (I must post as AC) I'm gonna respond to this one.

    The problem is the following.

    Some have said that much research is made by taxdollar, thats true. But this is a different kind of research, it aims as general understanding of the body and the processes that is has. This research IS important but you cannot compare it to the development of a specific drug.

    Say you discover a possible way to cure a decease. This is often the result from expensive research that is made blindly, you don't know what you are looking for. This costs lots of money.

    Normally there are three stages of clinical trials to establish if (1) it works (2) is safe.

    To make those clinical trials (and those are required to be allowed to sell the substance ofcause) you must have LOTS of researchers, we are talking about houndreds around the globe. Not only do you pay for this people but also for their equipment and so on.

    It may sound insainly expensive for you but the fact remains that it DO often cost billions of dollars to develop a new drug. If you take a look at the companies we talk about here not all of them makes a profit at all, some takes losses. This is not because they are "greedy" and "charge way to much", if it was so they would have huge profits.

    So, if you want new cancer, parkinson and aids drugs to be developed this kind of money just have to be made on sales. There is no way anyone is going to pay say one billion for researching something that others then steal.

    1. Re:You are wrong. by Anonymous Coward · · Score: 0

      Forgot to mention it but clinical trials often takes between five and eight years.

  204. drug companies and money by ChannelX · · Score: 1

    It amuses me to see people talking about drug companies and the money used for research, etc. I have several doctor friends who are *constantly* wooed by the drug companies, since they started doing their residencies, with big parties, etc. These are not "rent a hotel room" deals either but swanky parties at very expensive restaurants. I'll start feeling bad about drug companies losing money over something like this when they're not pulling shit like I mentioned above. Its sick that people cant get meds they need in this day and age but drug companies have no problems with throwing expensive parties to get doctors to use their drugs.

    --
    My blog: http://jkratz.dyndns.org/~jason/blog/
  205. Right Wing Shit by Anonymous Coward · · Score: 0
    If you think this guy has his priorities mixed up, give him a call at 540-574-3452, or tell him in person, his name is John Drummond, and he lives at 727 Northfield Court, Harrisonburg, VA, 22802.

    Since he believes in total freedom, he surely endorses both the posting of this publicly available information, my request for you to call him, and my desire to post this anonymously.

  206. Think of it this way... by Anonymous Coward · · Score: 0

    If a 1 time injection (ew, needles, make that pill) vaccine to prevent the catching of aids, and every other STD, plus influenza was invented, would you be angry if governments stole it ten years after it was invented and gave it free to everyone in the world? To beg the question, lets pretend that a corporation actually did all the reseach and tests and fact finding for every bit leading up to it (which, technically, is impossible, but lets pretend.)

    If not, welcome ot the days of free love and less sexual uptightness on the part of the conservative.

    Or would you rather have millions die?

    Personally, I don't really care about millions dying. There are too many people already. But I do care that someone I know (and like) might be hurt.Since I _do_ have people I care about, I place THEIR individual rights above that of any patent law. If necessary, I would burglarize a drug store to get that miracle pill to save whomever I love.

    To simplify the IP issue even further, lets pretend we're on the Enterprise' and have replicators. If the replicator has no food models, and you have a patented food model you could (unlawfully) program in to prevent both yourself and whomever you care about in this life from starving what would you do?

    Note I didn't ask if it was reasonable or likely to occur, only, _if placed in that scenario with no way out_ what would you do?

    If you would stoically starve slowly to death, and condemn your fellows to do the same because "it's the law" I think you should think further. Think about if a vote was taken by the 3 people on a deserted island that someone needed to be eaten, and you lost the vote 2-1. Would you, for the sake of unaninimity, change your vote and make it 3-0? Or would you defend yourself, or would you take your chances with the sea? Either way, you break the law or you die.

    1. Re:Think of it this way... by Chris+Hind · · Score: 1

      Enterprise? One time magic pill that cures everything? Are you some sort of pathetic nerd? Fuck off, geek, and come back when you know what the hell you're talking about. None of your situations are remotely realistic or have any bearing on the current situation: the appropriation by a government of millions of dollars worth of private property and the consequest long term damage to the health industry and prospects for disease treatment that that entails.

      --
      nal 11
    2. Re:Think of it this way... by Anonymous Coward · · Score: 0

      Could you clear something up for me? I haven't quite decided whether you're a pretty good troll or an absolute jingoistic corporate-media-fucktoy microencephalic idiot. Could you clear that up for me?

      Thanks for the help.

  207. I agree with nothing in your post except ... by GoofyBoy · · Score: 2


    .. for your english grammer/spelling.

    >Now they are using a public health problem as an excuse to void a valid international patent because they did not get the agreement they wanted.

    If there is any reason why to break an patent wouldn't this be it? "I'm sorry you have to die/suffer, but there are international patent laws to uphold."

    >White farmers losing their property in Zimbabwe, because its not fair that they have it.

    Not the same thing. This example has one group both fighting for property and the ability to work. The Brazil situation has one group wanting to make money and another dying/suffering.

    >Basically Brazil breaks the agreed internation law and makes the stuff for free, thereby forcing other nations to either follow their example of pay the difference.

    Wrong. Roche will not make the pills. Brazil does. If I produce pills in my basement, besides lost potential sales, it costs Roche NOTHING. Unless their accounting department are counting on every HIV patient as revenue, this will never show up in their bottom line.

    >Reduces the possibility of region specific drugs NOT being developed because companies rightfully fear losing all investment.

    No... as long as it happens somewhere in the world there will be drugs produced. Because it will spread to richer nations and there is more profit off of rarer conditions. (Because if you get it, you HAVE to pay for it and the drug companies can charge anything they want). And most of these "regions" are already poor. They can't afford expensive drugs right now. Remember Brazil?

    >Raises spectre of loss of intellectual property on other levels, and more and more are confiscated for the "public good"

    Welcome to the real world. Wars have broken out for the "public good". Oppression of miniorites have been due to the "public good". The artifical patent rights of some company is pretty minor compaired to this.

    >Increases the likelyhood of similar industries leaving "hostile" countries furthering the problem that country faces.

    Thats the risk each individual country takes. Don't see what the problem is. Its a simple pro/con thing. Obviously Brazil thinks its worth it.

    >Who can judge what is a fair price for something?

    Like human suffering? Thats the question Brazil had answered.

    >Apparently people are willing to allow those with the guns to do it, and not realize its the first step to losing their own rights.

    What does this have to do with anything? Where does guns come into a patent dispute between a company and a country? Talk about a wild tangent.

    --
    The surprise isn't how often we make bad choices; the surprise is how seldom they defeat us.
  208. Stealing food for hunger... is it stealing? by keepper · · Score: 1
    OK, once again, most slashdot users like to be counter-trend without really analyzing things for themselves..


    Here are the facts:

    Many people ARE dying of AIDS in brazil. And the world

    Brazil DID try to come to an agreement with the swiss patent holder, lik eit HAD done with anoither patent holder, to try to lower the price. ( yes people, it is commong practice for there to be different prices for different sections of the world, it's called economics)

    If brazil has an AIDS problem, the world has an aids problem... AIDS is a mutating and transmitable decease.. guess whow it got spread around in the first time. So it is in the world's best intesrest to deal with this.


    Yes i believe pharmaceuticals working on aids drugs should get their right compensation, but i think the issue in this is much bigger. I believe that global govt's should be involved in this. There should be some sort of collaboration into fighting this, and more affordable drugs, maybe thru global financing, is definetely a way to go. Face it, this has long turned into a WORLD crisis...

    Unfotunately, since no real solutions or global colaborations are indeed in place ( they are all basically being planed, proposed). This is turned
    into a case of Stealing foor for survival... LITERALLY

    This is not a clear case... it's as grayer a case as you can get...

    Just my opinion... Of course am right. :-P

  209. human life != infinite value by skeptic · · Score: 1

    I think it is quite clear that a human life is not of infinite value to the public, nor to any individual.

    The life-threatening risks we take everyday (for the sake of saving some $) discredits the argument that saving "one life" justifies stealing from another. (Do you drive a car? Is it the safest you can buy? If not, why?)

    Poor has always been, and always will be, a relative term. *Everyone* is poor in one aspect or another. If being poor were to justify stealing, we'd all be thieves in a chaotic society ruled by those with more coersive power. Although you may disagree, this is not how we live today.

    Human behavior is driven by incentives, which in all cases I can think of is linked to profit (not just in $ terms - think about happiness, love, even exercise). Drug companies (and their employees) operate in a world of trade, in which currency has been introduced to make the way we go about exchanging our goods and services more efficient (bartering and the double-coincidence of wants never worked too well). Accordingly, these companies (and their employees) are motivated by $ profits, which, I must say, if a very reasonable thing, because developing drugs is a very, very, very costly venture.

    The profits earned from one drug do not simply cover the costs of developing that same drug. Pharmaceutical companies are constanting failing in their attempts to find treatments and cures for our ailments. A failed attempt costs just as much as a successful one.

    Take away the drug companies' incentives, and their development efforts will most definitely go away. And no one, and I mean no one, benefits in that case.

  210. Yes, they are victims. by mosch · · Score: 2
    Let's take a real world example. A man is happily married to his wife, and since they're in a monogomous relationship, they don't use condoms. The man, unbeknownst to the wife, has been nailing his secretary and has gotten HIV. She still thinks he's just working late every once in a while. The man then gives the wife HIV.

    Explain to me please, why she is a culprit, not a victim.

    I'm looking forward to your reply.

    1. Re:Yes, they are victims. by DivineOb · · Score: 1

      Such cases are incredibly rare though...

      I doubt there are any published numbers on it, they are so rare...

      So basically... who cares?

      --

      I must burn in hell, suffer and pay for my sins
      But Gods the one who's losing, Satan always wins!

    2. Re:Yes, they are victims. by mosch · · Score: 2
      yes, those are rare, but people who lie about being tested clean are incredibly COMMON. a large amount of people will tell their partner that they've been tested, neglecting to mention that it was 3 years ago and they've had unprotected sex with 11 people since then.

      I was giving an example of an abuse of trust that even a fool could recognize.

    3. Re:Yes, they are victims. by kootch · · Score: 1

      and because of this, the country of Brazil should go ahead and start copying a drug that a company spent millions of dollars researching, testing, and creating without compensating this company.

      yes, there are always exceptions.

      the spouse should get a divource, sue her errant husband for all of her medical bills related to the HIV/AIDS virus.

      He should be paying for her medical bills as well as his own instead of getting the country to rob the company that did all of the research (and spent millions doing it) to put out the medicine.

      How's that for a response?

    4. Re:Yes, they are victims. by david614 · · Score: 1

      >How's that for a response?

      Callous, criminal, and immoral, that's how it is.

      Narrow minded bastard.

      --
      ELITISM: It's always lonely at the top. Uninvited company is rarely welcome.
    5. Re:Yes, they are victims. by kootch · · Score: 1

      nice way to give three terms but not explain your justification for that name calling.

  211. Re:India, Brazil, China... half the planet already by Hast · · Score: 1

    Oh please, DOS is hardly an OS by todays standards. No multitasking, no memory protection. Technically it's an OS, just like a T Ford technically is a car.

    And yes, there are a lot of free (beer) RTOS's, they are hardly easy to develop though. If OS's were easy to develop would it have taken the Open Source community so long to make GNU/Linux and the surrounding software (GNOME,KDE, window manageers etc.) this long to be developed.

    Now the big benefit of programming is that it's rather cheap and easy for a layman to do it on their freetime. It's not like you're likely to do some molecular biology research in the basement.

    If more areas had developed in the same way as Open Source then the world would be a much better place for a lot of people.

  212. Convenient... by virg_mattes · · Score: 2

    ...but you only addressed one of many points the parent poster made. What about the other points? Keep trying, and in the meantime, make an effort to remember that AIDS is a disease, and not just a social issue.

    Virg

  213. Re:What a fucking moron by Anonymous Coward · · Score: 0

    Brazil spends a large share of their
    public health budget in that drug alone.
    They have tried to negotiate with Roche
    to lower prices without success.

    But of course, as a self centric american,
    you have no clue of what happens outside your
    own country and give more value to gross profit
    than human lives, especially from such third world countries...

  214. Wrong + Wrong = Right ? by Anonymous Coward · · Score: 0

    So does this mean that two wrongs DO make a right?

  215. I'm glad you know how to use WHOIS by omarius · · Score: 1
    I would argue that by doing this, you are infringing upon my rights (since you seem to intend for your action to annoy/harm me).

    I would also argue that you are a childish idiot, since you see fit to use such tactics since you disagree with me, rather than actually trying to formulate an argument. Are you, perhaps, a scientologist? Maybe your brave and righteous action will prompt someone to find a way to do something really harmful to me -- but that would certainly not prove me wrong!

    Anyone who wishes to call, write, or visit may certainly do so! I just hope not in a harassing manner. :)

    -Omar, PS: good job decoding my .sig.

  216. You People Are Missing The Point! by macsforever2001 · · Score: 2, Informative

    I've been reading the arguments back and forth about this issue. Some people think that lives are sacred and hence breaking the (IP) law is OK. Others say that the ends does not justify the means and other arguments.

    Well *forget* the morality of the issue and look at it from a practical viewpoint. If countries are going to break international law to distribute medicine, then what reason will drug companies have to find cures or even treatments to these diseases? None. As it is, a cure is completely unprofitable to large drug companies because Brazil and other 3rd world countries who can't develop or afford it themselves would simply "pirate" it. But they will suffer come the next great epidemic. The drug companies will ignore the big diseases because they are not profitable, instead they will stick to the profit centers of headache/pain relief and fat reducing drugs. IOW drugs that don't save lives but only make you feel better *without actually helping anyone*.

  217. semantic point. by 3am · · Score: 1

    don't confuse things too much.

    it definitely is stealing.

    however, the grey area is in the ethics. ie, 'is it ethical to steal food for hunger?', or, in this case - 'is it ethical to break patent law for humanitarian reasons?'

    phrased in that way, i agree with you. saving human life outweighs monetary concerns.

    i know it's kind of nitpicky, but i think it's important to note the distinction.

    --

    A: None. The Universe spins the bulb, and the Zen master merely stays out of the way.
    1. Re:semantic point. by keepper · · Score: 1

      Yeah, that's what i had meant to say...

      But the actual saying slipped my mind...
      so i wrote somthing similar... hehe

      :)

  218. Killing 150M people "Insightful"?? by Gorimek · · Score: 2

    Carpet bombing? Yeah, that's very smart.

    ...stop developing drugs no one will ever pay you for

    Which this is of course not a case of. All rich countries, where they no doubt make at least 95% of their profit, will still pay full price for their drugs.

    1. Re:Killing 150M people "Insightful"?? by Anonymous Coward · · Score: 0

      Have you been paying attention to the senate recently moron? There are bills out there to allow importation of foreign "cheaper, non USP" drugs.

      Hmm, is Brazil foreign? So the US will be paying full price? I think not.. once this bill passes, the market will be flooded with brazilian vampire pills.

  219. While good, not great by rapett0 · · Score: 1

    While many people have pointed out that the R&D needs to be compensated, and it is expensive, I must say a few things. For one, it is, but like all companies wanting to recoup something, they are claiming more then it really is. Sure it may have cost a billion to develop, but when they claim it cost 10 billion, something is highly askew. Others have mentioned they can get the money back from rich companies, and others counter that argument that people will just get the drugs in Brazil. I find that hard to believe. However, even so, to be honest, very *few* people could ever afford the drugs on their own to begin with. So whats the solution? More public research and government *produced NOT funded* factories. Why? Because they can be held more accountable then any multi-national and it can directly help the people and not worry about bottom lines.

  220. Time for a REALITY CHECK and some FACTS! by Tord · · Score: 4, Insightful

    I see loads and loads of comments here in support of the medicine company that either bashes or seriously questions Brasil's decision in this matter. I also see how their comments are given high moderation points for their insightfullness and I also see flaws in their reasoning and logic.

    I therefore thinks it's time for a reality check and discuss some FACTS before we start to take sides:

    1.Quite some comments says or hints that Brasil is breaking "international laws". Wake up. There is no international body declaring international laws. What Brasil is breaking is international AGREEMENTS on how to treat patents. Brasil is in their full right to break this agreement if they discover that it costs more and gives less than they anticipated. That the medicine company is crying "foul" is just to be expected, but their handling of this situation really asked for it.

    2. How much of the medical research is actually financed by medical corporations that rely on patents for their income? I have no real statistics, but I remember reading that here in Sweden around half of the funding of cancer research is financed by "Cancerfonden" that gathers donations (from government, companies and individuals) for cancer research. Add to that all funding done by institutions as universities and hospitals and you find that commercial medical research is in the minority. Remember, this is in Sweden where we have an unproportionally big medicine industry compared to our population.

    3. Remember that patents isn't just a protection of your discovery, it also blocks your competition from inovating along the same branch! Patents both rewards and stiffles inovation from time to time. There is no proof whatsoever that the patent system has led to a higher rate of innovation in any field ever. We have just followed a logical string of thoughts and reasonings to come to the conclusion that patents do increase inovation. This reasoning is built on the assumption that we have a mostly correct perception of the world.

    4. People here are commenting on how patents affect a business that they don't know anything about. Many falls into making the same kind of generalisation that we constantly have to defend ourselves against, that patents are good and drive inovation and that there would be much less inovation without it. We know that it isn't true for software development. How can you state it as a truth for another industry that also differs a lot from normal mechanical innovation without really knowing anything about that industry?

    5. Doesn't the fact that we are forced to chose between peoples lives and getting money to future research that will save peoples lives tell you that something is wrong with the system? We need competition and rewards to get research in medicine, but we don't need the blocking (in both research and applying the results) that the patent system gives.

    There are other ways to raise funding, encourage competition and give rewards than just applying the patent system. Isn't it time we take a look at some other possible sollutions now that we clearly can see that the patent system doesn't work as it should in the medical field?

    If the system is broken, then fix it...

    1. Re:Time for a REALITY CHECK and some FACTS! by Anonymous Coward · · Score: 0

      If you spend X amount of money developing something you must earn atleast X amount of money on selling it, as simple as that.

      Patents is a absolut must if those kind of drugs will continue to be developed.

    2. Re:Time for a REALITY CHECK and some FACTS! by Anonymous Coward · · Score: 0

      I rememeber when AstraZeneca's (or Pharmacia Upjohn, don't remember which) patent for Losec was about to expire, they had had it for 20 years and made lots of money on it. But guess what, it wasn't until the last year they started doing som massive research to get a replacement drug to save them for the next 20 years.

      They'd had 20 years to come up with something, but failed. Apparently it wasn't worth investing enough money until they started to see the end of the money rain.

      One might wonder what had happened with say a 5 year patent, would it force companies to keep innovating.

      Do you think, say 3dfx would be push the limits of the 3d accelerators if they had no competition because they held a 20 (or 10,5,?) patent for home 3d-accelerators?

      In the computer business you have to constantly innovate and inprove in order to stay on top.
      In the medicine business you can get a killer drug and milk every penny out of it for 20 years and then move on.

      Sure I am not entirely fair, but you see my point. (hopefully =))
      I don't think that the patents are necessarily bad, but 20 years is way to long time. The best would perhaps be that the companies get a patent for as long as it takes for them to cash in say 2x the R&D for the drug and then open the market.

      Oh well getting a little tired and slow... please don't flame =)

      /Johan

  221. AIDS is not a disease by Anonymous Coward · · Score: 0
    neither is HIV infection. From what I have gathered from the media, the general public and special interest organizations (and the elitists that are in them)... AIDS is non existent and a hoax. Because if it was a disease, a disease that kills with no known cure, then logic would dictate that it were treated as such.

    Case in point: A nurse brings in her mother who is HIV positive, but is brought in for something different (which very well could have been complicated or caused by the HIV infection's immune system destruction). When gathering a patient history for the patients benefit this little fact is ommitted. Later, another nurse is stuck (but thankfully turns out negative) and then bloodwork is ordered and found that the patient was indeed HIV positive. When the daughter (again, a nurse) is confronted about this, she gets very hateful, vehement and abusive while yelling (yes, yelling) that it was 'none of their business'. When the doctor asked how a nurse could completely disregard the safety of the patient and the staff due to ego and pride, disregarding the privacy policies in place, she just got more vehement. So, it was easy to see that her superficial and emotional security was more important than her mothers or the staffs life.

    Another case involved AIDS education. It has long been known, that due to the very nature of the HIV virus (uhhh, yes I know it is redundant), that there were certain activities, locations and conditions that increased the probability of infection. For example, rubbing open wounds together is rather high, while touching a 'normal' (non bleeding or wounded) person is very low. Anyway, because the rectum is designed by nature to absorb, it is VERY high on the list when considering sexual vectors. However, the liberals (read: hypocrits who cared NOTHING about helping the sick and reducing the cases... education, logic, reason and compassion are antithesis to a liberals) anyway, the liberals picketed, vandalized, etc until that was removed. So, typical to the liberal credo of 'if it feels good do it, no matter what the consequence' and 'ignorance is bliss' created a situation where people were NOT EDUCATED. Far be it for someone to have usefull information in order to make an informed decision, they would rather have it filtered from them or would rather lash out at reality for the choices they make. I suppose if I smoke and it is proven it is dangerous then I will lash out at the facts and the messenger. Oh wait! Then I can sue everyone and me and my relatives can now be independantly wealthy.

  222. Ratios by virg_mattes · · Score: 2

    Well, perhaps the wording should have been virtually no progress. One vaccine in several decades does after all put them somewhat behind the curve in medical research.

    Bully on them for that vaccine, tho'.

    Virg

  223. I'll give you two free-market friendly approaches by FreeUser · · Score: 2
    Name one please. It's easy to stata there are alternatives but it's not as easy to develop a well thought out plan to replace the current IP system over a set period of time.

    I'll do one better. I'll name two:

    • Government funded or subsidized research, either through private labs, academia, or a combination of the two. This has a long and venerable history of success (think: defense spending and the assorted technologies which have come out of it, as well as many of the medical breathroughs that have been made, many of which have subsequently been patented despite having been funded in large part from public moneys ... an abuse if there ever was one which at one time was unthinkable but has recently become all too common, and another very good reason to get rid of government entitlements to 20-year monopolies).
    • Branding, either through coporate consortia or individually. Branded drugs (e.g. Bayer asperin) compete successfully with their generic counterparts even after patents expire. Consortiums can be formed to develop, market, and brand a new technology without relying on a government entitlement to a 20-year monopoly ... product X being branded as "official product developed by Y" will have a trust/quality factor many people are willing to pay for which Tiawanese competitor Z cannot offer (trademark law being what it is). Some will opt for the knockoff, others will prefer to pay more for the brand name. Again, this has a long proven track record in cases where patents are overturned or rejected altogether, as well as in cases where they have (at long last) expired.


    Competition will keep the prices fair and reasonable. It may take longer to recover an expensive R&D development, but it is recoverable.

    Oh, and ad homonem attacks aside (where does Star Trek or television come into any of this, other than your absurd stereotyping?) I may have given you credit for more intelligence than you deserved (the above two scenerios would count as fairly obvious to me, and a number of others have occurred to me with a little thought, but for which I do not have time to enumerate as I have to get back to work), but that hardly makes the point I made "absurd" by any definition.
    --
    The Future of Human Evolution: Autonomy
  224. Re:Drug Companies Rarely Design the Drugs They Sel by Anonymous Coward · · Score: 1, Informative

    "None of the companies who currently hold patents on them were actually involved in doing the research that generated the drug and demonstrated it's initial efficacy."

    THAT IS FALSE.

    Go search on google.com for the history behind the drugs. All the current protease inhibitors we're invented at companies. Not by the govt.

    This may not be true for AZT, the compound which was found (as an anti-cancer therapy that turned out to have too many side effects) under a govt. grant back in the 60's before AIDS was known. BUT, it was a private corporation Burroughs Wellcome that first found that the AZT compound was effective against AIDS.

    Just go look up the patent on a drug (type in its real name) on

    http://www.uspto.gov/patft/index.html

    It will show who the original INVENTORS are by name and where they worked (Assignee refers to the ORIGINAL not current). Here are some to try out.

    Zidovudine (AZT/ZDV)
    Stavudine (d4T)
    Didanosine (ddI)
    Inclinavir (crixivan)
    Zalcitabine (ddC)
    Ritonavir (Norvir)
    Lamivudine (3TC/Epivir)
    Nelfinavir (viracept)
    Saquinavir (Invirase)
    Nevirapine (Viramune)

  225. Yo retard, we'd never see a cure for AIDS by Anonymous Coward · · Score: 0

    We can sell the drug.
    Why make the cure?
    We can sell drugs over and over, but once we sell a cure, we're out of buisness.

    I don't see alot of people making money off polio anymore...

  226. does brazil give free treatment for ALL diseases? by Anonymous Coward · · Score: 0

    Another thing that is tired about this argument is that is always seems to be ok to do anything if it involves AIDS. Brazil gives away free drugs to anyone with AIDS. Do they give free treatment to anyone with cancer, TB, or even other STDs? I know that AIDS is 100 fatal, but they are talking about a lot of money to slow down the progression of a disease that is preventible in the first place. Curing cancer actually saves the person's life and a person's personal actions may or may not contribute to cancer.

  227. How clean is alcohol? Burning the field=polution by John+Harrison · · Score: 1

    While living in Brazil I often wondered whether alcohol-based fuel was really cleaner. Instead of using corn (as we try to in the USA) they use cane sugar to produce the alcohol.

    Burning the cane field is part of the harvesting process. It removes the leaves making the cane easier to handle. It also covers everything within a mile in ashes. It was always a joy to come home and find my laundry on the line covered in soot.

    Does anyone know how polluting it is to burn the fields?

    As a side note, many Brazilians that I met felt that alcohol-powered cars were inferior. They were VERY hard (if not impossible) to start when it was cold (not very often where I was) and the exhaust smelled like a frat party.

  228. Lorenzos Oil by Anonymous Coward · · Score: 0

    Lots of people having been complaining about how unfair this is to big corportions

    "But think of the mega-Corporations" does not have the same rings a "But think of the children".

    You really have to decide what your priorities are, put the good of society and _real_ people ahead of personal/corporate profit and greed.

    Some have suggested that this will harm research and development. That is highly amusing to hear in the same forum where people regularly mock the statement "Non would write software for free".

    If you still dont think that people will do R&D (or make art/write programs) unless they are getting paid then i strongly recommend you watch Lorenzos Oil. The film is a great and deeply moving true story.
    http://us.imdb.com/Title?0104756
    http://www.myelin.org/index2.html
    [i wish slashdot would automagically turn properly formed URL into links]

    [posting as AC so as to avoid obliterating my Moderating to this story. I think its a stupid rule and i should be able to mod (up) any comments except my own]

    1. Re:Lorenzos Oil by Anonymous Coward · · Score: 0

      [posting as AC so as to avoid obliterating my Moderating to this story. I think its a stupid rule and i should be able to mod (up) any comments except my own]



      fuck, fuck fuckity fuck fuck!

      it did not work and i just wiped out 5 Mod points.

      This blows!

  229. Hey all you "This will slow R&D fools" Look he by CrazyJim0 · · Score: 1

    If you're going to be making billions off selling your drug, you can spend millions researching it... This is what you guys are upset about. Loss of patents = loss of money so no one trys anymore...

    Thats good, if you want to sell people drugs. If you want to maximize money coming in, you should sell them drugs they need to buy as often as possible...

    Kinda like planed obsolecence... or when your mechanic breaks stuff in your car as he fixes it... Or like kiemotherapy, how it puts cancer in remission, but since you have radioactive dye, you'll be back in the hospital...

    Where is the incentive for making a cure to AIDS, or cancer? If you make a cure, you put tens of thousands of people out of a job. Do you think the AIDS drug industry wants to find a cure? Research to cure diseases should be federally funded, not designed by the corrupt private sector.

    Remember the thing that people would sell you air if they could restrict your access to it? Same thing is happening with researching drugs vs a cure.

    Break all the patents, patents suck. We need a new way of looking of dealing with the wrongs of capitalism... Intellectual property or trade secrets, planned obsolecence, and competition that breeds evil... Definately need to be addressed.

  230. Put your MONEY/TIME where your mouth is. by FallLine · · Score: 2

    Ahem, just because "some" people are willing to work for "nothing", does not mean it is a feasible OR a superior means of satisfying society's needs. The Open Source movement hardly answers even a MERE fraction of today's software, and the costs of R&D are almost laughable in comparison, not to mention the SLOW development times. Did you know that: The average drug costs 600million dollars to bring to market today (almost all of the costs are incurred in DEVELOPMENT, not research). While this figure does include the drugs that never make it to market, it does not take into account several other extremely powerful issues. For one, the average time to market (development & approvals time) is almost 15 years long today--that's an EXTREMELY tough position to be in financially. Secondly, of those drugs that make it to market, only a small fraction actually BREAK EVEN on total R&D costs (Hint: This does not even include marketing costs).

    The drugs companies are VERY much dependent on a few "hit" drugs to offset the R&D costs for ALL other efforts (not just that one drug).

    So to answer your two assertions:

    First, poor countries' appropriation of these few successful drugs may MAKE future R&D efforts for ALL drugs specific to those regions economically unfeasible [even for a non-profit!!], not just this one AIDS drug. Brazil et. al is capping the only upside [even to break even alone], while doing nothing to relieve the downside and the risk.

    Second, Open Source style development of drugs is an absolute and complete joke. Almost all of drug prices are the result of REAL costs. [Profit is a relatively small component of it, especially when it is adjusted for risk.] There is a world of difference between a LOOSE handfull of hackers around the world working PART TIME on a little code here and there for fun and the challenge, and that that is required to get a drug off the ground. It requires a vastly different mindset, not to mention a great deal of resources(The great costs still must be shouldered by society, minus a little bit of profit). You also can't ignore the time involved and the relative lack of reward per dollar/time/etc.

    No, government MIGHT be able to manage it, but not a bunch of people poking around. However, it'd still cost society just as much money, maybe even more. Those costs may be borne out more evenly if government does it, but that's also kind of the point of insurance/HMOs (in theory).

    Anyways, you miss the point, MIGHT != IS. If GNU/GPL/Whatever can do it cheaper and better and faster, let them. But until that time, only ONE system (IP + profit) really delivers; don't break it just because you have a theory.

    1. Re:Put your MONEY/TIME where your mouth is. by DrZZ · · Score: 1

      Amen! There isn't a thing in the world stopping "open source" drug development. There are even starting points. The NCI has
      data for
      ~50,000 compounds tested in AIDS and cancer screens. Take the data and go to town. But if you are not willing to do the work and invest the time and resources, don't bitch about the people who do.

    2. Re:Put your MONEY/TIME where your mouth is. by Hard_Code · · Score: 2

      In the end the question is:

      Is the cost of disincentivization of pharmaceutical companies (and therefore the risk of future products not being developed) in wealthy countries greater than the cost of millions of lives of those in poorer countries who cannot afford the drugs?

      To prove that this is the case you first have to prove to me that these drugs companies 1) will not break even without massive sales outside of the top few wealthiest countries 2) knew this *before* they started research/development (after all, you can't be disincentivized *before* you actually know what you want to do). And yes, taking into account that a fixed amount of money has to be spent for "ongoing" research not tied to any given product. Seeing as people in third world countries can't afford (and therefore are not buying) these drugs in the first place, I think it would be hard to make the above argument.

      And no...I don't mean that LITERALLY drugs should be developed under an "Open Source" model. I mean that profit is not the only motive for human endeavor and even *if* private for-profit pharmaceuticals become disincentivized, inevitably someone somewhere will be developing drugs (probably governments).

      --

      It's 10 PM. Do you know if you're un-American?
    3. Re:Put your MONEY/TIME where your mouth is. by FallLine · · Score: 2
      Is the cost of disincentivization of pharmaceutical companies (and therefore the risk of future products not being developed) in wealthy countries greater than the cost of millions of lives of those in poorer countries who cannot afford the drugs?
      This is a distortion; the choice is not so simple or black and white. The two are not mutually exclusive. We can support intellectual property while simultaneously providing drugs to poorer nations. The drug companies can (and have)protect their ability to make a profit in poor countries, while still saving just as many lives. They have done this through special programs, while those programs may not been ideal (debatable), that does not mean the other extreme is a better solution.

      will not break even without massive sales outside of the top few wealthiest countries
      You are assuming that these drugs were developed substantially for sale in wealthy countries, when AIDS is almost entirely IN poor countries, proportionately so, especially certain strains of it. Furthermore, the goal is not MERELY "breaking even". To "break even" on a few hit drugs, is to lose money hand over fist on the aggregate, since most drugs do not break even (whether or not IP is respected).

      knew this *before* they started research/development (after all, you can't be disincentivized *before* you actually know what you want to do).
      No, their intentions for THIS drug are hardly relevant. The issue, as for as society is concerned, is the development of NEW drugs. Once Brazil has demonstrated to the drug companies that they are effectively unwilling to pay the drug companies on these highly demanded drugs, they have demonstrated that ALL efforts that depend on these markets are no longer economically feasible. The drug companies recoup their costs on just a FEW drugs, only a FRACTION of those that actually MAKE it to market. You kill possibility of a hit drug on a given market, you kill the entire market. End of Story.

      And yes, taking into account that a fixed amount of money has to be spent for "ongoing" research not tied to any given product.
      But that is not exactly true. This is true in the EARLIER RESEARCH phase, but not in the development phase, which is where at least 90% of the costs occur. In the development phase, you get a pretty good idea of the targeted market. This means, if you discover that a certain drugs has properties that can only be used in fighting, say, a certain kind of malaria, it is a no-go.

      Seeing as people in third world countries can't afford (and therefore are not buying) these drugs in the first place, I think it would be hard to make the above argument.
      This is not exactly true. Cannot afford != Cannot afford to pay anything. It's also not this simple, as I mentioned earlier, the drug companies HAVE in fact setup programs to deliver drugs at or below marginal cost. Furthermore, Brazil showing utter disregard for this patent can have implications far far broader than JUST the loss of potential revenue in this one country. It can create a black market for illegal generics to not-so-poor countries and even to the United States. It can result in an avalanche effect.

      even *if* private for-profit pharmaceuticals become disincentivized, inevitably someone somewhere will be developing drugs (probably governments).
      So you'd give up all FUTURE fruits from the drug companies, because you can only see the present. That is short sighted. Yet you assure yourself that _maybe_ "someone" will solve the problems you create for you. Excuse me, but no non-profit or government entity has proven itself yet capable of delivering like the drug companies have.

      Did you ever stop and ask yourself why 99% of the worlds modern drugs come from the United States and other Western Countries, all which happen to respect IP? India, China, Russia, and many others, they all have plenty of intelligent and well educated people (despite poverty in some areas), yet none are homes to significant domestic innovation (in drugs, or otherwise). Although India has just started some efforts, they're almost ENTIRELY for the United States and other countries. Any wonder?

  231. Re:2 Billion R&D == 5 Billion profit by Anonymous Coward · · Score: 0
    http://www.galen.org/news/041201a.html

    Using Fortune 1000 data.


    "But a closer look reveals that drug companies aren't all that profitable when compared to many other companies. According to Fortune, the median profit of the 12 drug companies included was 18 percent in 1999. Most of the companies were in the 15 to 20 percent range.

    By contrast, Nabisco reported a 36 percent profit for that year. And for most of the 1990s, Coca-Cola had higher profits than the median drug company. Yet no one accuses Coca-Cola and Nabisco of price gouging on soft drinks and cookies.

    Even Gannett, publisher of USA Today, made 17 percent in 1999 -- right up there with the drug companies."


    Maybe my dad's restaurant should ship food over to Africa, because his profit margin is as good to better than the average drug company!


    Or try this sites:
    http://www.yourdoctorinthefamily.com/commentary/ co mm017.htm

  232. Good thing, but... by Anonymous Coward · · Score: 0

    We cannot forget that it may create some impact, mainly in researches and making of new medicines.

    Im from Brazil and I really dont see the government investing seriously in researches. I think they have the right to break the copyrights (I think thats right), but they cannot just hold on techonogy not created by them (Ok, created by billionarie company, but the innovation is their). They should help develpment intead of making high expenses with futile things (and some imoral, like paying the bill of bankrupt companies).

  233. Watch out Brazil by kabloie · · Score: 1

    The Swiss Guard are coming. You don't want to end up on the business end of a halberd, do you?

    Thats 2d6. Or 2d8, I forget...

  234. New slogan: by Anonymous Coward · · Score: 0

    "We want your money".

    Funny how they don't mention that, isn;t it. It's always something like
    "We think of YOU first"
    or
    "Making the world a better place"

  235. Who cares about AIDS? by evilviper · · Score: 1

    I can understand governments spending millions in research money to study and attempt to cure cancer, and the rest of the serious diseases, but AIDS does not qualify. AIDS is not airborne, does not get transfered through touch, and does not spread in the ground water. It is does not really qualify as a health threat since you can decide not to get it. There are pratically no cases of people getting aids through infected blood transfusions, or getting it from parents. While it does happen, the huge majority decided they wanted to participate in risky behaviour, more than they wanted to live. I think that decision should be honored, and they should be reminded of their decision when they go begging for a cure.

    --
    Slashdot gets worse every day... Pipedot: News for nerds, without the corporate slant
  236. Peoples Lives more important than profit by dh003i · · Score: 1

    Look, the lives of the people who are saved are far more important than the fucking profit made by drug companies. Drug companies ALWAYS recapture the R&D cost if their drug is worth shit, and if its worth something, they always make a profit, so hence their is motivation to develop. What drug companies want is to make 100 times the R&D cost. Now, drug companies to NOT need to make 100X the cost of R&D to be motivated to product cures. In fact, 1.5X or 2X is more than enough.

    For those of you not familiar with simple economics, be aware that just because a company is not making a profit -- or maybe if its losing money -- does not mean it stops making its product. In fact, companies will continue to operate and innovate when they are LOSING money, because the cost of going out of business would be greater than the cost of continuing business. That is, if they went out of business, they would lose even more money than they would if they continued business. Hence, they continue operating.

    Now, Brazil has NO obligation whatsoever to consider the IP "rights" of corporations. Their ONLY obligation is to consider what is best for their citizens. Nor does Brazil have any reason or obligation to obey international law or international agreements if it finds these to be at the expense of its citizens. International laws are a violation of the sovereignty of the people of nations anyways.

    That said, other governments should and may do the same thing when they deem it necessary, including the US government. Remember, the GOVERNMENT and NON-PROFIT ORGANIZATIONS donate LARGE sums of money to corporations. We should either demand that they make their products freely available to the government, or with-hold funding. The money of the US taxpayers -- PUBLIC MONEY -- should not go towards making a privatized resource.

    Finally, let me state that though Brazil's decision is right, their implementation of it is flawed. Brazil needs to accumulate a vast storage of many different HIV-inhibiting/destroying drugs. They then need to treat their patients with all of them simultaneously. This may seem rather calculating but it is necessary. No one "cure" or "blocking mechanism" for HIV will work. HIV is a virus and it evolves rapidly. Any given drug to destroy HIV will destroy maybe 99.99% of HIV viroid particles, but there will always be a few left. So you need to use different drugs simulatneously. there may be billions of HIV viroids within an infected individual, all of them slightly different and mutated, some which have mutations which make them more immune to drugs. You need to treat the patient with enough drugs so that it is improbable that even ONE HIV viroid will be resistant. This means accumulating 10, 20, 30, or even up to a 100 different treatments and using them all at once.

  237. They aren't breaking the law!!! by John+Harrison · · Score: 1
    As I understand it Brazil in not obligated to honor patents that were granted prior to their entry to the WTO. I think this happened in 1996 or 1997.

    They honor patents on new drugs but on the older ones they have figured out a great way to get them for cheap:

    1. They reverse engineer the drug.
    2. They figure out how much it would cost them to manufacture it themselves.
    3. They approach the drug companies and say, "We can make this drug for $x. We are not obligated to honor the patent. How much are you willing to sell it to us for?"
    4. Drug companies figure they can either sell the drug to them for cheap and still make a profit or lose the market.
    5. So now Brazil is either buying the drug from the drug company for cheaper than they would otherwise be or they are making it themselves.
    They can't do it on drugs that were patented since they joined the WTO or they will get kick out. This strategy might come back to haunt them when the drug companies decide to jack up prices for Brazil for new drugs in order to get back at them.
    1. Re:They aren't breaking the law!!! by Artagel · · Score: 2

      I doubt step 1 is "reverse" engineer as happens with software or computer chips and their microcode.

      A U.S. Patent has to enable one of ordinary skill in the art to make and use the invention without undue experimentation. Otherwise, it is an invalid patent (here). Also, in the U.S. a New Drug Application, or NDA (or even an Abbreviated New Drug Application, ANDA) ends up explaining the forumulation of the drug. Although NDAs and ANDAs are not public documents, Brazil's equivalent of the FDA probably has them.

      Although formulations can vary from country to country, it is probably just a matter of looking up the recipe.

  238. Einstein did have children by Mzilikazi · · Score: 1
    Albert Einstein never had kids.


    Einstein had several children; A girl named Liserl (supposedly retarded and put up for adoption), and two sons, Hans Albert and Eduard (the latter also being mentally unstable and institutionalized).



    http://www.usd.edu/~aelverud/advcomp/albert.html

    --
    Random Musings at Rum Smuggler
    1. Re:Einstein did have children by fmaxwell · · Score: 2
      Einstein had several children; A girl named Liserl (supposedly retarded and put up for adoption), and two sons, Hans Albert and Eduard (the latter also being mentally unstable and institutionalized).


      Thank you. I never knew that, though it certainly shoots down the troll's "good genes" theory, doesn't it?

  239. going to shit? by Ender+Ryan · · Score: 2

    No, this world already is shit. It is shit because people like yourself feel you have some God given right to ideas and information. You would rather see millions die than let a country "steal" "IP".

    Anyone who has not grown up with the whole idea of IP being forced down their throat would call that insane.

    --
    Sticking feathers up your butt does not make you a chicken - Tyler Durden
  240. Re:If there were real competition, this wouldn't b by codeforprofit2 · · Score: 1

    There are several companies making aids drugs.

  241. International Patents by Hrothgar+The+Great · · Score: 1

    What makes you think that the drug companies' patents SHOULD be able to be enforced internationally? The entire world does not consist of one government; there still are borders if you hadn't noticed. If Brazil thinks that the idea of patents on pharmaceuticals is becoming harmful to their society, they have a right to decide not to participate. It's as simple as that.

  242. Taxpayer funded research used for patents by yerricde · · Score: 1

    There's nothing to keep a government from funding malaria research, and freely licensing the result.

    Except campaign contributions: "If you publicly fund this research and then give it to ME, you'll get more money to help you get elected." Happens all the time.

    --
    Will I retire or break 10K?
  243. Pseudo-libertarianism by boosman · · Score: 1

    Many of the comments on this story remind me of the fact that so many people on the Net describe themselves as libertarian in nature (or something close to it), except when it comes to something they want that belongs to someone else.

    Example: Pharma patent rights. A true libertarian would say that, for the durations of their patents, pharma companies have the right to license their creations at any price they choose, or even not at all. $1/dose, $10,000/dose, or "we're not selling" would all be valid. Instead, we get Slashdotters arguing that drug companies should be forced to give away their creations, or to sell them at a "fair" price (i.e., a price not determined by the free market).

    Example: Music distribution. A true libertarian would say that, subject to their owning the copyright, record labels have the right to license songs however and to whomever they wish. If they want to license a song so that listeners can enjoy it every other Tuesday, then that's their right. Instead, we get Slashdotters arguing that record labels should be forced to distribute their songs on standardized, "fair" terms (i.e., terms not determined by the free market).

    If you want to believe that the government has a role in all this sort of stuff, and should have this kind of power, that's fine, though I'm not on your side. But don't come crying to Slashdot when the government uses all its wisdom and power to tell you what you can do with your computer and your Internet connection. To argue for freedom of speech on the one hand and government control of private intellectual property on the other is intellectually dishonest at best.

    -- Frank

    1. Re:Pseudo-libertarianism by Oswald · · Score: 1

      From the Libertarian Party's home page:

      Examples of the heavy hand of government acting to successfully encourage or invigorate the market are easy to find. Take the patent system. The U.S. Patent and Trademark Office grants exclusive rights and ownership to the developers of intellectual property. Inventors and innovators can then expect huge potential profits from their hard work and research dollars.

      But without such governmental controls there would be much less incentive to devote resources to new technologies since anyone else would then be free to appropriate the inventions without having taken any risks. Patents thus encourage technological innovation, and both consumers and suppliers benefit enormously from this Constitutionally mandated government handout.


      I added the emphasis in the second paragraph. The point of the patent system, according to Libertarians and according to the U.S. Constitution (please don't make me find that reference too), is to benefit both suppliers AND CONSUMERS--in other words, all members of society. I hardly think it can be argued that just 'doing without' drugs that can potentially limit (and, we hope someday with further advances, eliminate) an epidemic of a fatal disease benefits society. Since it's certainly possible to set the price for the drug so high that a country of limited means (all of them, if you raise the bar high enough) can't pay, 'doing without' may be the only option to breaking the patent.

      In this particular case, the patent system has been found not to work properly, and the situation is grave enough to justify (in some minds, at least--I admit it's a difficult problem) stripping the patent protection. I don't know what amount the government of Brazil was willing to pay for the treatment in question, and I don't claim that I would be able to judge it fair or unfair if I did. I do know, however, that there is more to life than money.

    2. Re:Pseudo-libertarianism by dh003i · · Score: 1

      You are so full of shit. Libertarianism means you believe in individual rights. Now it is perfectly clear that nothing violates individual rights MORE than intellectual property laws -- they prevent individuals from sharing information and prevent them from using publicized information to manufacture a drug that could help them. In short, intellectual property laws VIOLATE the right to freedom of speech -- as they restrain us from sharing information and VIOLATE the right to freedom of action. That is, patent laws would prevent me, as an HIV victim(for example) from using the information published in a patent to produce a drug that could prevent the HIV from becoming active.

      You clearly know nothing of libertarianism. I suggest you read a book called "Information Libertaion" -- a true libertarian book. Here's the url for it:

      http://www.uow.edu.au/arts/sts/bmartin/pubs/98il /

    3. Re:Pseudo-libertarianism by boosman · · Score: 1

      It's a relief to find out that you know more about libertarianism than leading libertarians themselves. Whew! I was misguided there for a while. For example, from the Libertarian Party website:

      We further hold that the owners of property have the full right to control, use, dispose of, or in any manner enjoy, their property without interference, until and unless the exercise of their control infringes the valid rights of others. We oppose all violations of the right to private property, liberty of contract, and freedom of trade done in the name of national security. We also condemn current government efforts to regulate or ban the use of property in the name of aesthetic values, riskiness, moral standards, cost-benefit estimates, or the promotion or restriction of economic growth. We specifically condemn all government interference in the operation of private businesses, such as restaurants and airlines, by either requiring or prohibiting designated smoking or non-smoking areas for their employees or their customers.

      And from the Cato Institute website:

      Policymakers shouldn't ban any category of technology as the marketplace works through these difficult issues. Likewise, force should not be used to "aid" the sharing of IP, such as emerging calls for the imposition of compulsory licensing requirements on record companies. Such forced "contracts," with their accompanying price controls and regulatory dynamics, have no place in a nascent industry that desperately needs to embrace voluntary deals. If companies go too far in locking up information, other companies (and consumers) have the option of dealing with less-restrictive entrepreneurs.

      Clearly the Cato Institute and the Libertarian Party have been misleading me as to the true nature of libertarianism. Thanks for setting the record straight.

      -- Frank

  244. Re:Newsflash! Slashdot readers readily hand over t by 3am · · Score: 1

    have you noticed that the non open source companies aren't doing so great? come up with a more compelling reason.

    --

    A: None. The Universe spins the bulb, and the Zen master merely stays out of the way.
  245. Re:2 Billion R&D == 5 Billion profit by dswan69 · · Score: 1

    This of course assumes that these profit claims are true - why should we trust them? The SA court case clearly demonstrated that the pharmaceutical industry has lied about every aspect of their finances. It was very clear that this industry is totally corrupt.

  246. R&D Costs by Anonymous Coward · · Score: 0
    In another article by NY Times some months ago...



    The drug companies' argument is in essence a defense of high profits. Even in the United States, the cost of drugs is provoking questions about whether continued research and development really depends on giving companies a 20-year monopoly to charge whatever price they choose, especially since they are often marketing other people's discoveries. The manufacturers generally spend twice as much on marketing and administration as they do on research and development.



    Something seems to be wrong with patent's law. We are talking about human lives, don't we?

  247. NYT article by Gorimek · · Score: 2

    Here a New York Times article with a bit more information. This is apparenty pretty standard procedure in Brazil.

    http://www.nytimes.com/aponline/international/AP -B razil-AIDS-Drugs.html?searchpv=aponline

  248. A couple of VERY key points you missed by DG · · Score: 2

    There are a couple of very key differences in this situation:

    1) The ABM treaty is an agreement between STATES, and thus, an implied agreement between the people in those states (the state speaking for the people) A corporation does not speak with the voice of a people; it is an artificial entity to enable individuals to make money.

    States are responsible to the people they represent. Corporations are responsible to no-one.

    Unilaterally breaking a treaty is to thus break with a people - and is a far more serious kettle of fish.

    States appropriate private property (for the good of the state) all the time. Usually, it's compensated for, but not always.

    2) As a practical matter, a drug company has little it can do in form of retaliation. A state, however (especially a nuclear state) is not so limited. There may be serious repecussions to breaking the ABM treaty.

    In many cases, unilateral treaty-breaking can be seen as an act of war. In the best of cases, it's not very damned polite.

    Breaking this _particular_ treaty also has strategic implications. If one believes that an effective missile shield can be erected, then one who has missiles, but no shield, had best strike BEFORE the shield is in place.

    Thankfully, the current Russian government seems to have more sense than that. I'm not sure that is univerally applicable to all nuclear powers.

    By continuing on its current course of action, the current administration is walking a very thin line. It's not at all a simple case of "erect shield, protect Americans". It's more like "attempt to erect shield, piss off all other nuclear powers, invite first strike, further reputation as a treaty-breaking country not to be trusted" A military success perhaps, but a diplomatic disaster.

    It would be far, FAR better to negotiate a new ABM treaty that allowed the new system (having one's cake and eating it too) than to just go ahead and build it anyway.

    I'd point out that the last major Western power to ignore the terms of major military treaties and do what they wanted was Nazi Germany, but then I'd wind up invoking Godwin's Law. ;)

    --
    Want to learn about race cars? Read my Book
    1. Re:A couple of VERY key points you missed by mblase · · Score: 2
      The ABM treaty is an agreement between STATES, and thus, an implied agreement between the people in those states

      International patent law is likewise an implied agreement between states. I wasn't drawing a comparison between corporations and nations, but between one international agreement and another.

      Brazil is essentially declaring a state of emergency in their war against AIDS and using this to justify breaking international patent law. Bush percieves the proliferation of black-market nuclear weapons as reason to declare a minor state of emergency and break the ABM treaty.

      Both are diplomatic disasters, but the only difference is that Brazil is upsetting a corporation while the US is upsetting other countries. But if Brazil's actions were to someday lead to other pharmaceuticals restricting trade with developing countries, for fear of losing profits, the end result is the same as if they'd angered the United States government.

      Both actions are defensive and for the protection of each country's individual citizens (and neither, despite your mention of Nazi Germany, involves encroaching on other nations' borders). The only difference is the immediacy of the threat. If Middle Eastern nations were already firing off nuclear missiles toward each other, no one would dare say Bush's actions were unjustified.

  249. Re:2 Billion R&D == 5 Billion profit by Anonymous Coward · · Score: 0

    Where do you think all of that money goes? For gold-plated toilet seats and expensive executive jets.... I won't argue or deny that executives certainly have their perks and high salaries, but the majority of the profits are reinvested back into the company in to the form of new labs, equipment, etc... Plus, many drug companies pay out decent dividends to their shareholders and owners. Owners probably like you - with you mutual funds and stocks and 401k's!

  250. So, with what unit did you serve? by DG · · Score: 1

    I assume if you're going to start throwing around the word "coward" then you must have walked the talk yourself, done time in military service, and earned the right to say that.

    So where did you serve?

    It's real easy to advocate military solutions when it's not YOUR ass on the line.

    DG

    --
    Want to learn about race cars? Read my Book
    1. Re:So, with what unit did you serve? by DivineOb · · Score: 1

      Actually, oh reactionary one, I meant that they wouldn't have the courage to respond to his arguments...

      and what do we have here... you didn't respond to this argument...

      --

      I must burn in hell, suffer and pay for my sins
      But Gods the one who's losing, Satan always wins!

  251. Re:2 Billion R&D == 5 Billion profit by dswan69 · · Score: 1

    Of course they like to obscure their real costs and how much of the total cost was spent marketing the drug rather than actually developing it. If they claim $2 billion to bring a new drug to market then that would be around $500k-$750k for R&D with the remainder going towards marketing (advertising, kick-backs etc.)

  252. Why is this moderated "Troll"??? by sleight · · Score: 1

    This post is insightful! Not a troll! Someone meta-moderate these people, please! Just because this post disagrees with the typical /. mentality of free beer for everyone doesn't make it a troll! This person has a damn good point!

  253. Tetanus by Sebastopol · · Score: 1

    Exactly! Notice that there is 1 year backlog on tetanus shots? Hospitals are being urged to use them sparingly. Why? Only one company makes them today (due to competitve market reasons), and there's not enough profit.

    --
    https://www.accountkiller.com/removal-requested
    1. Re:Tetanus by crayz · · Score: 1

      Notice that there is 1 year backlog on tetanus shots?

      Umm...no? I got one early in life, I got another when I smashed my finger at around age 12, and then I got another a few years after that("just to be sure")

    2. Re:Tetanus by Sebastopol · · Score: 1

      I meant recently, in the past few years. Check this article: http://www.salon.com/tech/feature/2001/03/08/tetan us/index.html

      It's a little sensationalist, but recently a local news network checked with doctors in the northern california area and confirmed that there are shortages for people who just want a booster for no apparent reason.

      It's not 100% doom-and-gloom, but it is a tiny bit scary...

      --
      https://www.accountkiller.com/removal-requested
  254. Here you go... by KnightStalker · · Score: 3, Informative

    For Roche themselves, the company mentioned in this article. From part of their 2000 annual report, in a PDF ("Finance") available at: http://www.roche.com/home/investor/inv-finance/inv -reports/inv-reports-2000-annual-report.htm

    Marketing and distribution 8,746 (2000) 7,813 (1999)
    Research and development 3,950 (2000) 3,782 (1999)

    Numbers are in millions of Swiss francs.

    Clear enough?

    --
    * And remember, it's spelled N-e-t-s-c-a-p-e, but it's pronounced "Mozilla."
    1. Re:Here you go... by KnightStalker · · Score: 1

      BTW, I looked at Bayer first, then Roche. I couldn't find marketing expense information on Bayer's site within 5 minutes or so, so I moved on, but I believe their gross profits and R&D costs were on the same order as Roche's. I didn't look at any other companies.

      --
      * And remember, it's spelled N-e-t-s-c-a-p-e, but it's pronounced "Mozilla."
    2. Re:Here you go... by Anonymous Coward · · Score: 0

      Clear enough??? Not really when all you can bring me one of the lamest of the "big" pharma co's. Roche is a dying puppy. Bring me info on Merck, Pfizer, et al.. and then we'll talk.. By the way if you really want the dirt, go to http://www.imshealth.com/... of course you'll have to pay for the data, but then you don't do that do you??

  255. We live in the world of "Atlas Shrugged" by Anonymous Coward · · Score: 0

    Stories like this one have been in the news for months now and I read each one of them with dismay.
    We appear to live in a society where claims of need are used to justify abuses of individual rights. I emphasize the word claim because in almost every case, the justification is not valid.

    Salon has carried several stories about the efforts of activists to force big pharma companies to relinquish their patent rights for AIDS drugs that are to be copied in South Africa.[1, 2]. It doesn't matter that in order to increase these people's life expectancy it would make more sense to provide them with adequate food and sanitation. The Economist carried a story a while back (can't link to it) that when AIDS drugs are given away free in Africa, they get resold on the gray market and end up being purchased by people in western countries looking to obtain a cheaper treatment regime. The poor Africans benefit, because they can use the money in a more efficiently to feed their families and provide for the other necessities. The North American or European who buys the gray market drugs benefits since they pay only 60% for the drugs. So who pays for all this? Big pharma. It's forced charity in the name of humanitarianism.

    It's popular to piss on big pharma with the retort that they make money hand over fist and they deserve to have some of their enormous profits taken away from them. Maybe someone could enlighten me on this issue. Do pharma stocks give incredible returns on investment? Should I pull all my money from under my mattress and out of Nortel (Ha!) and stick it into Roche?

    1. Re:We live in the world of "Atlas Shrugged" by Oswald · · Score: 1

      Well, the last question is a pretty easy one: yes.
      I don't know how long this link will be good, but it displays a graph showing that Merck (I picked the biggest pharmaceutical company, since I didn't have any better criterion) has approximately tripled the returns of the S&P 500, Dow Jones Industrial Average, and the Nasdaq composite (which are all surprisingly close to each other) for the period 1970--present. I don't think anyone has a real good explanation for how an industry can earn economic (sometimes call excess) profits for such an extended period, but there it is.

  256. you're gullible by abde · · Score: 2


    wrong - R&D funds are actually on par with advertising, marketing, and CEO salaries of the Big Pharm Corps. If their R&D budgets were at risk they can cut back on Mr Fat Cat.

    Anyway, are you really so gullible to think that a Pharm Co would not do R&D ? that's like General Motors deciding not to build new models of cars. Its counter to common business sense.

    Profits from a single drug like TYlenol are so vast that the R&D costs are easily met. You're jkust spouting a typical conservative argument that favors $$ and BigCorps over common sense.

    --
    Don't blame me - I voted for Howard Dean. http://dean2004.blogspot.com
    1. Re:you're gullible by syates21 · · Score: 1

      Boy, if our CEO read your message I'm sure he would be scrambling to find out where he picks up his paycheck for the same amount we spend on R&D.

      Since about 25% of our revenue goes back to R&D, he'd be making a cool $750 mil a year. Not too bad, even for a CEO salary.

  257. Now, take that one step farther by Platinum+Dragon · · Score: 1

    Since we're playing the software analogy game... if an "open-source" drug company lets their bugs all hang out... then a "closed-source" drug company has the same bugs, only not publicized, and people don't get anything but the major releases... and if there are bugs in those releases, too bad, use this upgrade or wait for the next one.

    It's times like this I'm glad analogies are never entirely accurate... though how close to the target I'm hitting here, I don't want to know. Yet.

    --

    Someday, you're going to die. Get over it.
  258. does AIDS drugs really wok? by Frederic54 · · Score: 1

    I know there's some drugs so the patient will suffer less, or feel better, but in fact it does not *cure* AIDS no?
    I just hope the day a true cure will be found, it will not be patented, so everyone in the world will be able to take it for 1$.

    --
    "Science will win because it works." - Stephen Hawking
  259. You can indeed have it both ways by DG · · Score: 2

    It is quite possible to have state-sponsored medical research without having to have state ownership of the drug companies.

    One way to do it is similar to the military procurement process - put it up for competitive bid.

    The state puts aside funds for a certain purpose - say a cure for AIDS. Some of those funds are front-loaded to drug companies seeking the contract. The rest is used for milestone bonuses, and a REALLY big bonus at the end for the first company to find the cure. Once the cure is found, release the formula to the world as public domain.

    As long as the money is good, there's no reason why you won't see drug companies signing up - especially as R&D usually has spinoffs.

    The world doesn't need to be pure capitalist or pure communist. A decent mix of the best of both gets a lot more done.

    --
    Want to learn about race cars? Read my Book
  260. Even more so. by hotsauce · · Score: 1

    The patent rights granted in Brasil are actually granted by the Brasilian Government. Since they grant the rights, it stands to reason they can also take these away. In fact, Brasilian law says these rights can be taken away in case of war or national emergency. The US has such eminent domain laws too. By saying that Brasil can not choose to override patents that they have granted you are saying that a soverign democracy can not choose the laws they make or change.

    As for research being affected, the company knew the law before it invested in research, and that didnt seem to stop them. In fact, if someone can't pay, the company doesn't get money whether the patient lives or dies. You can't squeeze blood from a stone. Instead, companies expect to make money from the people that can pay.

    Patents are granted for the benefit of society. Democracies are allowed to choose the laws they believe benefit them the most. By saying corporations should be granted absolute unchangable rights you are taking away from democracy and supporting a corporation-dominated world. It's a frightening trend seen even here on /.

  261. Re:2 Billion R&D == 5 Billion profit by Anonymous Coward · · Score: 0

    Yes, they're making a profit, but they took a $2 billion chance to do it - what about all the other companies doing aids research who are billions in the hole because they found nothing? Risks have to pay off, or no one will take them.

  262. Medical (r)evolution! by Anonymous Coward · · Score: 0

    Isn't it time for the human race to evolve beyond greed?

    The worlds governments should terminate medical patents altogeather, and eliminate corporations that profit from other peoples illness and death, then set up an internationally funded (that means EVERY country on the planet paying a large but reasonable fee) research center, with the greatest minds on the planet, that allow all countries to benefit from this kind of research.

    1. Re:Medical (r)evolution! by tlaclair22 · · Score: 1

      Greed as I understand it, is the unscrupulous desire for somebody else's money. Selling a product on the free market benefits all parties and hardly qualifies as greed.

    2. Re:Medical (r)evolution! by metachimp · · Score: 1
      Then you understand it wrong. Greed is the desire to make as much money as possible, in any way possible, damn the consequences. It is the unscrupulous pursuit of wealth, excessive desire, and capitalism without a conscience. Greed may include wanting someone else's money, although that's probably more adequately expressed as 'avarice'.


      Is Merck being outright greedy? Perhaps. More likely they're holding out because if they make an exception for Brazil, then they have to make an exception for everyone.


      The pharmaceutical companies make a lot of products that help people. However, in the face of public health crises, they can easily afford to lower their profit margins, or operate at cost for drugs that can ease the suffering of people with illnesses like AIDS, or malaria, or what have you. They can easily make up for it with 'luxury' drugs like Viagra (I know, Pfizer makes that) or Propecia, or something nonessential like that.

      --
      The system has failed you, don't fail yourself. --Billy Bragg
  263. Drug patents make me sick by ReelOddeeo · · Score: 2

    The statement

    Drug patents make me sick

    Might well be a true statement, if you're too poor to aford the drugs which are overpriced due to patents, and you end up sick because of it.

    --

    Those who would give up liberty in exchange for security and DRM should switch to Microsoft Palladium!
  264. Re:This is an excellent thing to cheer... NOT by speedbump · · Score: 1

    "Software patents are bad."

    Why is that? You equate a software patent to a government monopoly. I don't get the connection. Patents are typically owned by non-governmental parties, and ENFORCED by governments. Get over it.

    "Ideas are not property, nor are inventions inherently something to be possessed..." The Patent office, and myself, disagree with you. This type of rhetoric about how an idea cannot be owned is typical Communist pap. "From each according to his ability, to each according to his need." Bah! Weath redistribution (whether material or intellectual) is robbery, pure and simple.

  265. Re:You know, the likely response is going to be. . by Anonymous Coward · · Score: 0

    They already have pills in the work that will make the medicene inactive if it's tampered with.

  266. HIV doesn't cause AIDS!! by tlaclair22 · · Score: 1

    True Story!!
    HIV is nothing new, probably been with the human race thousands of years.
    AIDS is a syndrome, not a disease.
    AIDS, the syndrome, is made up of 30 or so previously existing diseases, pnuemonia, lymphoma, etc.
    HIV negative people die of AIDS, too.
    The common link between AIDS patients is not HIV, but a compromised immune system.
    This is the tip of the iceberg here, if you want to learn more, please read Inventing the Aids Virus by Dr. Peter Duesberg, available through the standard channels.

    1. Re:HIV doesn't cause AIDS!! by metachimp · · Score: 1
      Even if HIV is not the cause of AIDS, that doesn't mean that it can't be effectively treated with the drugs that are out there. Most of the drugs that are used with AIDS attempt to bolster the immune system, orotherwise slow the progression of the syndrome. Most of the drugs available don't target the HIV retrovirus anyway, since viruses of all kinds are notoriously hard to treat (the common cold).


      At any rate, these treatments are affective, because people with AIDS are living longer, and not getting devastatingly sick at such a rapid clip, and these drugs to tend to stave off the opportunistic infections that eventually kill people who suffer from AIDS.

      --
      The system has failed you, don't fail yourself. --Billy Bragg
    2. Re:HIV doesn't cause AIDS!! by tlaclair22 · · Score: 1

      Bolstering the immune system is exactly the right path to follow. But you touch on the keystone of this whole situation. If HIV doesn't cause AIDS then what does? What makes some lymphoma AIDS and other lymphoma lymphoma? And why should they be treated differently by the medical community?
      It seems to me that if I go to the hospital with lymphoma but hiv negative they treat me for lymphoma and I get better. But if I go in hiv positive they treat me for AIDS and I die.
      Maybe some newer drugs bolster the immune system but the biggest one, AZT, absolutely does not. AZT is a drug that searches out cells about to divide and attacks them, stopping the division and killing the cell. The thinking behind this is that this will stop the 'spread' of hiv cells stopping the disease. But it knows nothing of the difference between the types of cells in the body, attacking all cells. So take a sick person with a compromised immune system and give them a drug that attacks every cell in the body, brain, heart, kidneys, immune system, bone marrow, etc. Is it any wonder they drop like flies? This stuff is pure poison.

  267. Treatment vs. Cure: way to go capitalism. by hanwen · · Score: 1
    Everybody is talking about the need to pay them to encourage development of new drugs. This is certainly true for new treatments, but what incentive do they have to produce a cure?

    I actually talked to someone working for a pharmaceutical company a few months ago, and he could confirm what you are saying: their R&D was targetted at producing medicines that could be sold over and over, because they generate much more revenue.

    (going a little off topic)

    I guess lots of pharmaceutical companies were a bit peeved when some Australian guy found out the cause of stomach ulcers 10 years ago. It turns out they are caused by a bacteria (Helicobacter Pylori), and can easily be treated with specific antibiotics. Before that time, you either had to use expensive anti-acid medicine like Zantac, which didn't cure anything, or have a part of your stomach surgically removed.

    --

    Han-Wen Nienhuys -- LilyPond

  268. This is not about profits over people. by Stu+Charlton · · Score: 1

    This is about a government that doesn't want to pay money that a corporation rightfully deserves.

    There's a number of arguments floating around that have a tremendous amount of ignorance about the global economic and political system. I'll pick three:

    1) "I can't believe people are justifying profits over people"

    2) "Evil corporations make money at the expense of lives"

    3) "AIDS research should be government funded"

    So here's my counter argument:

    - Profit is an objective necessity. It's not evil.
    - Companies that aren't profitable go away. If they filled needs in the past, those needs will potentially no longer be met once bankrupt.
    - Companies that research AIDS are doing so because there's a need in the marketplace.
    - There's a need for AIDS research because governments aren't putting enough resources into it
    - Governments aren't putting enough resources into it because their constitutents (i.e. those who democratically elected them) don't want them to. ("Cut taxes" , "cut spending" implies that something isn't getting done by the government anymore.)

    Since everyone in this forum seems to be focused on "profits over people", I'm going to explain my position on that one mainly, for the sake of (ahem) brevity:

    What do companies do with profit? Typically profit is placed in four areas: 1) "retained earnings", or re-investment in a company - 2) Dividends, or rewards to the owners of the company, - 3) Profit sharing, or rewards to the executives of the company, 4) Charitable donations.

    The reality is that profit is mainly used as a tool for re-investment. It is secondarily used as a means of growing wealth for investors. In past times (centuries ago), profit was primarily used for growing investor wealth, but this has changed a lot as capital markets have evolved rely much heavier on "value growth" in stock prices.

    Hence, profit, while an indicator of how investors will fare, is not necessarily the primary instrument by which investors gain wealth.

    Well, if profit is used mainly for re-investment -- not for lining shareholder pockets, what happened to the profit motive? You know, the main reason that people are apparently in business?

    Does profit tell us anything about *WHY* someone is in business in the first place? No.

    Profit is an objective necessity for corporations to stay alive. A company that loses money for too long is "bankrupt", and won't be around for much longer, and doesn't do anyone any good. It squandered resources that could have been put to better use. Profit is not primarily about greed, it is however about performance -- using resources (i.e. money) effectively. It says nothing about what a corporation does day to day, or what a manager must do day-to-day (things like marketing, human resource management, planning, innovating, communicating, and researching)

    The whole point to businesses in today's world is the nature of the relationship between organizations & society to meet our economic and social needs.

    Some organizations (businesses) fulfill each other's needs by sensing those needs (marketing), and responding to them (innovation & entrepreneurship), receiving money as an exchange for the value they provide to a customer.

    Other organizations fill society's needs by determining an agenda (organizing), finding people that agree with their needs (marketing) and asking for money to support them (donations). These are NGO's and non-profit organizations. (we need more of these)

    The former organization type is concerned with the productive use of economic resources in filling a need. The latter organization type is concerned with fulfilling a social agenda, using donations to sustain themselves.

    The whole reason we need profit is to ensure that these "for profit" organizations are run effectively and have a means to cover the inherent risks involved with any new venture.

    Since they don't solicit for donations, profit satisfies the market need for capitalists - i.e. people who will give money out to a risky proposition if they can make more money out of it (it could be called "gambling" by the cynical, but large scale investment gambling is a major reason the world has progressed so quickly..)

    So, it's not so easy that "people are dying for your stinking profit".. there's a reason for profit, and while Brazil's action is an isolated case, we can't view this as the beginning of a universal trend -- such a trend is not sustainable given our economic system (which will continue to remain so as no viable alternatives appear ready for the forseeable future).

    --
    -Stu
    1. Re:This is not about profits over people. by dh003i · · Score: 1

      Please, you are full of shit. The company publicized the information on how to make the drug -- that's called a patent. The company has NO authority over the government of Brazil. Brazil's government is sovereign over itself, and answerable only to the people of Brazil. The only interests of that govenment are the people of Brazil.

      Now, its absurd to say that any company is going to go out of business b/c a few government's refuse to pay them and make their drugs w/o paying. Drug companies make 10 - 100X the initial R&D cost. In fact, the R&D investment is earned back within a year -- usually 6 months. There is no reason why the company needs 10-100X the R&D cost. There is a perfectly good reason to continue developing with only a 1.5X net profit. Also, companies WILL continue to operate even if they are LOSING money, and are in the hole. Take basic economics, fool. Companies may continue doing business even when they are losing money/in debt because going OUT of business would be even MORE costly. That is, if they continue doing business for 5 years, they will lose say 10 million dollars, but if they declare bankrupcy they will lose 20 million dollars. So they continue doing business, until they lose less money by declaring bankrupty -- quite a while.

    2. Re:This is not about profits over people. by Stu+Charlton · · Score: 1

      Please, you are full of shit.

      Thanks for reminding me, I do need to make a trip to the loo.

      The company publicized the information on how to make the drug -- that's called a patent. The company has NO authority over the government of Brazil. Brazil's government is sovereign over itself, and answerable only to the people of Brazil. The only interests of that govenment are the people of Brazil.

      You're not confronting my argument.

      I'm talking about the argument that profits are evil, which appears to be a view taken by many members of this forum.

      But, to discuss the patent - naturally the company has no right over Brazil, but international organizations do have means of influencing Brazil's actions. (i.e. the WTO or WIPO). So, you see, the world is changing. Governments are losing their sovreignity because they have needs that aren't being met in by those governments - but those needs ARE being met by international corporations, (hence the trend towards globalization and free trade).

      Now, its absurd to say that any company is going to go out of business b/c a few government's refuse to pay them and make their drugs w/o paying.

      I never said that. I said that if this becomes a trend, it will be an unsustainable trend.

      Drug companies make 10 - 100X the initial R&D cost. In fact, the R&D investment is earned back within a year -- usually 6 months.

      Complete corporate costs & profit are the only figure that really matters when arguing about profit. Profit in terms of just the excess of R&D costs is very misleading. There are failed R&D projects to account for, overhead, risk, etc. that only can be analyzed by looking at the company as a whole.

      Having said that, I generally agree that excessive profit is undesirable, however I'm not sure anyone can really claim to "know" what "adequate profitability" is beyond those actually running the business.

      Also, companies WILL continue to operate even if they are LOSING money, and are in the hole. Take basic economics, fool.

      I am an economist (academically, not professionally). I wouldn't claim to be an expert, but I am well aware of the "basics" ,thank you.

      Companies may continue doing business even when they are losing money/in debt because going OUT of business would be even MORE costly.

      The key word is "may", and it depends very highly on A) whether they can restore profitibility in due course, B) whether investors feel the level of profitability is sufficient to long term sustainability.

      Considering you just told me to learn basic economics, please also note that refering to being "in dept" as similar to losing money makes you look like the fool.

      That is, if they continue doing business for 5 years, they will lose say 10 million dollars, but if they declare bankrupcy they will lose 20 million dollars. So they continue doing business, until they lose less money by declaring bankrupty -- quite a while.

      This is, uh, fuzzy math. You're picking numbers to suit your argument that has nothing to do with the situation I'm describing.

      I'm discussing the general role of profit vs. loss. Companies respond to market needs, but since those needs are driven by economic demand, it will stop responding to those needs when profitabliity disappears. If they don't move on to other things, they will eventually lose money to the point that they're not appropriately using their resources. Sustaining such actions leads to bankruptcy, which is undesirable to not just the company, but all of society.

      So, if you want companies to research things, you pay them. Or they'll stop.

      For this situation in particular:

      A company whose business is solely based on intellectual property a) must make a profit, objectively b) makes a profit by having better IP than other people, c) must prevent other organizations from "borrowing" it's IP, mainly because IP isn't just a bunch of "bright ideas", it's usually a body of work that takes tremendous economic resources to create in the first place.

      IP law is a set of general principles that the developed world has worked out over the past century to promote progress because commercial organizations MUST make a profit in order to function and hence require a system of IP protection to enable a sufficient amount of profit to be accumulated to cover the costs of the future.

      If you don't like the constraints inherent to for-profit institutions, then you have two choices:
      a) donate to non-profit research institutes
      b) vote in a government that spends your taxes on research.

      Did Brazil do the right thing? I guess it depends on what "right" means. They certainly did the moral thing (in the short term).

      But such actions may have seriously disasterous consequences in the long run if it turns into a trend where most developing countries flip the bird to the international economic and property system.

      --
      -Stu
    3. Re:This is not about profits over people. by Anonymous Coward · · Score: 0

      "Drug companies make 10 - 100X the initial R&D cost"

      With inside information I can say that this is a false statement.

      The research&development costs are enourmous, and patents are a must to make it possible for anyone to invest those kind of money.

      Otherwise you wouldn't see the drugs.

    4. Re:This is not about profits over people. by Anonymous Coward · · Score: 0

      "Brazil's government is sovereign over itself, and answerable only to the people of Brazil. "

      Not after it has been invaded.

    5. Re:This is not about profits over people. by Anonymous Coward · · Score: 0

      That's a very darwinistic view that many people seem to share.

      Profit may be the primary objective of corporations in a capitalist system but I must insist that the rights and lives of individual humans take precedence over corporate profit.

      Corporations don't innovate, discover, cure, or do anything other than manage profit.

      Individual human beings innovate. And not all people are motivated by profit. Read a little history and discover how many great men and women who contributed much to humanity 'died penniless'. It happens again and again and again....

      To say that a cure for aids can only come from a profitable corporation is delusional.

      To say that a human being must actually die to protect a corporation's profits is just fucking sick.

      And this, from Linux users???? Linus Torvalds isn't rich because he patented or copyrighted linux.

      Have a little faith in the human spirit, people.

  269. Some facts about the drug by nologin · · Score: 1

    While this may not be the most popular opinion, I'm siding with Brazil on this. Roche is going for a quick money grab, plain and simple.

    The drug "nelfinavir" isn't a cure for AIDS. It is only supposed to slow/stop the progress of the disease in the body. A patient who is on the drug has to stay on it for the rest of their life; even an economics 101 student knows that you'll eventually pull in more money with more lifetime customers by lowering the price of the drug rather than let a good portion of your potential clientele die because you are trying to gouge them.

    And I doubt anyone can successfully argue that Roche doesn't know this. They've been in business for over 100 years.

    Patent issues aside, it is undisputed that these people are infected with HIV, and there is no solution to make it otherwise. However, the drug can be produced by someone else; there is a solution other than Roche to produce the drug. Maybe the company should have realized this when they were ultimately denying these potential patients of their lives...

    And while patents are supposed to protect the innovations of a corporation, I don't think that any country would put the rights of the corporation ahead of the individual's right to live.

  270. Bullshit by Anonymous Coward · · Score: 0

    I don't understand people saying U.S. (or at least, U.S. companies) will lost money with Brazil producing the drugs while American goverment is comercially so close to China, the world's greatest pirate. In this case, between nuclear powers, the concepts are diferent?

  271. ONE HUNDRED BILLION DOLLARS by WinPimp2K · · Score: 1
    Its chump change for Austin Powers. Now go away till you can recognize a stupid movie reference before one rips your humourless throat out.


    Of course, rather than have that second rate international man of mystery pony up the money, one could just ask Derek Flint to whip up a cure in between pissing contests with Maxwell Smart and Joh Steed.

    --

    You either believe in rational thought or you don't
    1. Re:ONE HUNDRED BILLION DOLLARS by Anonymous Coward · · Score: 0

      Now go away till you can recognize a stupid movie reference before one rips your humourless throat out.

      Dude, now you're just being funny. A Roadhouse reference? Geez! Patrick Swayze is so last century!

  272. Roche is particularly bad by Anonymous Coward · · Score: 0

    Roche is definitely one company I don't feel sorry for. They plead guilty to "illegal collusive practices" (ie price fixing) in the vitamin market, and were fined $500M.

  273. GOOD! by Anonymous Coward · · Score: 0

    Good for Brazil! What makes man feel that he has any knowledge let alone what makes man feel that he owns any knowledge? Patents and secrets are counter-productive to the advancement of the human race as is grossly evident in this individual case. It is not until that we as a society do away with trade secrets that we as a race can truly become great and combat all of the ills that currently face us.

  274. One Word: Communism by Anonymous Coward · · Score: 0

    So why don't just confistigate Bill Gate's property and give it to the poor people? 100 billion dollars can feed a lot of homeless. It's for the public good - Evil Empire destroyed, software quality improves and poor people happy, right?

  275. Re:So many close minded and uniformed people posts by Anonymous Coward · · Score: 0

    Ok, look, I have been following this story through out the day, and I just can't stand it any more. It is people like this who need to have thier eyes opened up.

    If you think that AIDS is only caught by IDU (IV Drug Users) and Gays, you could not be more wrong. I would know. I am a straight man who got AIDS trying to help someone who had AIDS. Now if you think God is taking his wrath out on me, I believe you to be close minded and wrong.

    What would God have to punish me for? I am and have been a baptized Christian for years. I have lived a moral life. I do not use drugs and I am not gay.

    It sickens me to hear people like this say that AIDS is not an indiscriminate killer. It never asked me if I sleep around. It never asked me if I used drugs. It never asked me if I were gay. It just said, "Hi, I'm AIDS and you have me now!"

    Please think about what kind of stupid non-sense you are posting before you post it.

    Do I believe it is a good thing that Brazil did this? Yes I do. These drug companies have been price gouging the 3rd world countries for YEARS!!! and I say it is time that it stops! Perscriptions in these 3rd world countries are known to charge 4-10 times the amount they would charge someone here in the states. I say give us the higher prices, we (for the most part) have insurance to help with our bills! Whereas these people for the most part have nothing!

  276. This is not good (even if it wasn't patented) by Penguinoflight · · Score: 1

    Now they're going to make everyone take AIDS drugs, and these AIDS drugs will give more people AIDS then it will prevent. Then people in the US will be forced to take the pills also, nowhere will be safe.

    Though I disagree with a patent on a drug (drugs are parts of plants, created by God and therefore God owns all the rights to them), I'd very much like to see this patent hold, and I hope those swiss want to keep it all to themselves.

    --
    "And we have seen and do testify that the Father sent the Son to be the Savior of the World"
    1 John 4:14
  277. Comment removed by account_deleted · · Score: 2

    Comment removed based on user account deletion

  278. Re:FUCK PEOPLE WITH AIDS by Anonymous Coward · · Score: 0

    What about when your whore of a wife goes sleeping around with every guy/gal she meets? When she goes out, are you sure she isn't screwing someone else?

  279. From the British Medical Journal... by Brian+TNB · · Score: 1
    Here's the link

    Public funding is responsible for more R&D into AIDS than private corporations.

    Monetary incentives brings out the greed in people. That's not a side of humanity that I would particularly want to nourish.

    On a personal note, the sheer number of Slashdot posters that have reduced the very real AIDS problem into another version of "gubmit vs. freedom" is frightening to me. For the love of Jesus H. fuckin' Christ, people are dying, and we don't need rich uncle Pharm as a drain on resources. We can't fight a PANDEMIC half-heartedly. Nobody can.

    I guess I shouldn't be suprised, this sort of shit is not new; adolescent-minded White people have always had a reason for their abominations. Read your history.

    British Medical Journal 2000;321:833, Letter from Michael Schull, president, MSF-Canada

    EDITOR: Do drug patents kill? If they do the risk is felt overwhelmingly by the poor. AIDS will soon become the leading cause of death worldwide, and 95% of people infected with HIV worldwide live in the world's poorest countries. Effective treatments are mostly patent protected, with the result that the annual cost to treat a single patient with AIDS is up to 100 times the average gross domestic product per capita in developing countries.1

    These staggering facts have led to a campaign to increase access to essential AIDS medicines in poorer countries, including a loosening of patent protections on medicines.2

    Opposition comes mainly from pharmaceutical companies, which argue that without patent protection profits will dry up, eliminating the incentive to conduct research into new drugs. But who really pays for AIDS research? The reality is that taxpayers, not shareholders, have borne most of the cost. Publicly funded research councils have contributed hundreds of millions of taxpayers' dollars to AIDS drug research. Indeed, the Pharmaceutical Research and Manufacturers of America, an industry lobby group, estimates that private industry finances only about 43% of drug development.1 Five commonly used drugs against AIDS -- didanosine, lamivudine, nevirapine, stavudine, and zidovudine -- were developed largely as a result of public funds.

    --
    Wise man say, choose your enemies carefully, for you will become like them...
  280. Score 3 - Insightful??? by Anonymous Coward · · Score: 0
    Who the hell is doing the modding today? The People's New Socialist Way Committee?


    Let's see "insightful", that would be a profound or well considered expression. I think that Abraham Lincoln shouldn't have wasted all that verbage at Gettysburg. He could have just screamed out "Way to fucking Go!!!", and learned the economy of expression which can be heard at a frat boy's porno party.


    I see another posts with some well-articulated, perfectly valid points who was labeled as a "troll".


    As for all those who would encourage Africa to do the same as Brazil, why don't you read up on how the South African government has refused to distribute the drugs they were GIVEN by American Pharmaceutical companies who were intimidated by the international version of white guilt. You can find out all about it at www.andrewsullivan.com


    This is bad for R&D. Opposing it merely because it is patented and you think some patents are stupid is just criminal ignorance. Michael seems to be a communist with the political sophistication of a 5 year old in Sunday school who knows that Jesus loves him because the bible told him so. As to what crack these other would-be Chairman Mao's are smoking, Please try some smack, it will kill you quicker.


    Guess what people: AIDS is not spread by a lack of federal funding. It is spread by fucking and shooting up. The African president who decreed that his people stop fucking is not totally wrong, except in his expectation that his ignorant populace will actually listen to him.

  281. Re:2 Billion R&D == 5 Billion profit by Sinical · · Score: 1

    And look at that "Operating Profit as a % of sales" for last year: 35%! To me, that's bordering on obscene.

    To compare with another industry that people accuse of gouging, look at the defense contractor Raytheon. They don't appear to have a nice number laid out in their annual report (or at least not one I can find easily), but if "Operating Income" is synonymous with profit (dunno), then for 2000:

    $1.625 billion on $16.895 billion in net sales:

    9.61% operating profit: i.e., Roche was 3.64 times as profitable.

    So here's a word from an angry consumer: *fuck* you for charging what the market can "bear", as protected by Congress against laws allowing re-importation, etc.

    There was an article in the Washington Post's Outlook section (not a hard news section, granted) that had some reporting about how disingenous the drug companies are about development costs versus how much they spend marketing. I guess there was a study in the 60s (?) on the same idea, with the conclusion that drug companies gouged, but too many Congressmen are owned by Pfizer, etc. for anything to ever happen.

    Not that I'm bitter.

  282. true by tewwetruggur · · Score: 2
    you are right, a lot of the cost is actually in the development phase, which is what I do. If more of these companies were able to move faster and be more flexible, some of the headache-cost they incur would go away. Now, of course, companies like J&J or Lily are huge, and with that comes the red tape that slows things - so their development costs will always seem higher. They also move ponderously to reduce their risks, which makes their trials fewer, but larger and more rigidly planned, adding to the costs.


    I could go on for a while on a lot of these various points, but its probably not worth it, so I'll leave it at this.


    ah... the joys of development...

    --
    Hi! This is the Sig, blatantly attached to the end of this comment.
  283. Gee, thanks Mr. Wizard! by Brian+TNB · · Score: 1

    For every AIDS-denying doctor, there are thousands who are actually working to help the problem. If I were a betting man, I'd would have more to say about that.

    --
    Wise man say, choose your enemies carefully, for you will become like them...
    1. Re:Gee, thanks Mr. Wizard! by tlaclair22 · · Score: 1

      Thanks for the advice. In the future I'll do my best to ignore facts and apply myself to what 'everybody' believes and knows to be the truth. To start I'll do an historical review....

      The earth is flat.
      Blacks are genetically inferior.
      Pearl Harbor was a surprise.
      Witches cause bad crops.
      Jews are genetically inferior.

      and now...

      HIV causes AIDS.

      Thanks, I feel a lot better now.

      BTW, I have no problem with people working on answers, but the answers to this problem are behavioral not viral.

  284. Re:I'll give you two free-market friendly approach by tmark · · Score: 2
    Branded drugs (e.g. Bayer asperin) compete successfully with their generic counterparts even after patents expire.


    Your examples are absurd. Bayer asperin (sp?) competes successfully with generics precisely because of the market recognition and trust that developed as a result of Bayer's patent protection. And I would love to understand exactly why corporations are going to form consortia to do research and spend huge amounts of clinical trials and FDA hoops and marketing costs just to bring to market a drug which they brand but cannot realize proportionately large profits from.

    As for your example of defense spending...I seriously hope you don't want to use defense spending as an example of how the government really should be allocating resources. They have achieved wonderful technologies, to be sure, but at ridiculously high costs that few can deny. And from your stances I hazard a bet that you are just the sort of person who probably decries government military spending all the time except just now. Don't you ?

  285. Let's not forget the purpose of patent by LittleStone · · Score: 1

    The purpose of patent is not promoting innovation, but promoting innovation when innovation is too little.

    Problem of many innovations is the positive externality. Because the free market without patent fail to compensate the innovators for the goods an innovation done to others, the innovators lost incentive to innovate to the point that is optimal to the society. Patent is not to protect the benefits of the innovators. Patent is to protect the benefits of the society as a whole.

    Monopoly is also sub-optimal. However, through the use of monopoly power from patent, innovators have the incentive to innovate more. The existence of patent length is to balance the social cost of monopoly and the social gain of innovation.

    Now, the social cost of letting this monopoly on the AIDS drug stand is huge (the lost of lives of AIDS patients who would have stayed alive if they could buy those drug). The drug company has captured quite a lot of profits from it already. I would say that's enough for them to keep innovating. Don't you think it's time for the drugs to save more lives?

    Is the fixed patent length good for any situation? The answer is definitely no. In some situation, letting the patent length shorter is better to the society as a whole. I'm afraid this is the case.

    So stop fighting on the merit of keeping this patents or not. If you guys want to argue, argue how much gain to the society for saving those lives without the patents and how much lost to the society because of the discouragement in innovation.

    --
    A sig is redundant.
    1. Re:Let's not forget the purpose of patent by mimbleton · · Score: 1

      ". I would say that's enough for them to keep innovating. "

      And how did you arrive at that ?

  286. Re:2 Billion R&D == 5 Billion profit by Aexia · · Score: 1

    The difference is I won't die if I can't afford Coca-Cola or Shredded Wheat.

    And if I must have them, I can always go for the generic brands at the store at a cheaper cost.

    This is basically what Brazil is doing: producing their own generic brand.

    Safeway Select AIDS Cocktails.

  287. Don't be naive guys! by sjeqa · · Score: 1

    This is not a patent problem, but a
    political issue. Don't forget that
    next year 2002 is the Brazilian
    Presidential Elections and the
    current Government intends to
    be reelected.

    Furthermore, when the Brazilian Public
    Administration spends money to buy
    medical products, it's a kind of
    "income source" for those who are
    in the political class such as the
    Serra Minister.

    Brazil has enough money to pay for
    the anti-AIDS cocktails, but the
    money is concentrated on a privileged
    group that doesn't care about human
    lives. Probably, a little bit different
    from the inhabitants of developed
    countries...

  288. If Brazil's AIDS program is so successful.... by Anonymous Coward · · Score: 0
    Why do they have to steal a cure which more responsible people worked hard to produce?


    What a dumbass comment. Where did the people get the AID's from, public toilet seats?


    Contrary to your opinion, AIDS is not spread by a lack of Federal Funding.

  289. Liberatarians aren't JUST about profit motive! by Stu+Charlton · · Score: 1

    This is my real issue with the Libertarians of the world. There is no place in their world-view for the public project, done for the benefit of mankind. Everything must have a profit motive, and protecting profits has priority over all else.

    This is just not so! If you want to create or support a non-profit organization for AIDS research, Libertarians would applaud (well, I would)!

    But let's recognize the difference between a for-profit entity and not-for-profit. The former's mandate is to use economic resources productively to fill consumer needs.

    The latter's mandate is to use donations to pursue a social agenda, with economic efficiency being (somewhat) irrelevant.

    So, the task is to not complain about Roche wanting money, it's to A) vote for a government that will fund research, and B) create or donate to non-profit institutes.

    Or, C) pay Roche what they want.

    --
    -Stu
  290. Re:Newsflash! Slashdot readers readily hand over t by codeforprofit2 · · Score: 1

    Aren't they? Microsoft is doing great, so is Oracle and so is most software development companies with real working bussinessmodels.

    Microsoft has only lost a few percentage of their stockvalue this year, that must be a record in the IT-sector.

  291. Exactly correct. Bread lines for the R&amp;D by Anonymous Coward · · Score: 0

    The only reason I work is to get money to live the life I want to live.

  292. Re:Newsflash! Slashdot readers readily hand over t by mimbleton · · Score: 1

    "that drug companies making money is more important than saving lives. "

    You have it all wrong.
    No, drug companies should be making money so they can save lives.
    Without them this whole discusion is pointless.

  293. It's like a war. by chris_mahan · · Score: 1

    A country is fighting to save the lives of its citizens, and in the process violating international agreements. Heck! We wanted to end WWII, so we killed 400,000 + men, women, and children at Hiroshima and Nagazaki in 1945.

    Was that "cost" warranted to save the lives of millions of US servicemen who might have been killed in combat invading Japan? As far as the US is concerned, probably. As far as Japan is concerned, absolutely not.

    Likewise, Brazil is fighting a killing disease on a grand scale. Is the "cost" of violating international patent protection (profit protection really) warranted in the effort to potentially prevent the slow and horrible death of millions of Brazilians? I can guarantee that if I was the president of Brazil, I would say: "That was the easiest decision I ever made", just like what Roosevelt is reported to have said after ordering the anihilation of 400,000 men, women, and children in a nuclear holocaust.

    [On a complete tangent, Hitler would have been so proud of the speed and efficiency of our euthanasia program--instead or bringing the people to the hellish place, you bring the hellish place to them. 400,000 in three days: that comes to about 290,000,000 in 6 years.]

    --

    "Piter, too, is dead."

    1. Re:It's like a war. by Anonymous Coward · · Score: 0

      The main "disease" in Brazil is called FAMINE. It kills more people than AIDs, Cancer, accidents, etc.

      Those who have the "privilegy" of taking AIDs cocktails don't represent the Real population in that country. And Brazil is a Paradise in terms of Food...

  294. Have you ever travelled? by rkenski · · Score: 1

    You talk as if it would be easy to "educate" the population on how to avoid AIDS. It can be a very simple thing to do in your safe european home, but it is very hard in a big, complex and not so rich country such as Brazil.
    I am brazilian, and I am writing these from my office in São Paulo.

    First of all, sharing needles are a minor problem in Brazil. We don't have heroin here. People use other cheaper drugs, such as cocaine and marijuana. Smoking crack is perhaps the biggest problem, but it doesn't give you AIDS.

    People get Aids mostly for doing sex. Since you are so intelligent, I invite you to come here to Brazil and sucessfully convince the people that they have to spend a half of the salary in condons or stop doing sex, which sometimes is the only pleasure they can afford. It is only impossible. The government also doesn't have enough funds to give these condons for free. Nevertheless, it has done a lot of public campaigns to avoid Aids, but you can't solve a problem as big as this by only using advertisement.

    The fact is that breaking copyrights is saving lives. If you put in a balance one single life in one side and corporations interests in the other, I will always choose a living person. Come on! These corporations are going to fund research don't matter what Brazil does. They still have a huge (and rich!) market in the northern hemisphere, so why are you complaining about the last hope of a few miserables? Do you really think that Brazil (or South Africa, or any other non-developed country) would be the one to pay for the cure of Aids?

    Please, stop being so selfish and start to realise that there are some places (and people ) in the world that don't have the same opportunities you have.

    1. Re:Have you ever travelled? by omarius · · Score: 2
      Why yes, I have travelled, but it was mainly to another rich, Western country, so it probably doesn't count. And BTW, I'm American.

      It really, really sucks that sex causes AIDS. That's why it's such a successful disease. But if someone told me, "Having sex, especially outside of a truly monogamous relationship, might kill you," I would at least think seriously about commiting to one person, or to my right hand.

      I am aware that breaking this patent is saving -- well, really prolonging -- lives. But you could say the same for so many other things! I could steal all the food out of grocery stores and feed the hungry! I could steal all the drugs out of the drugstore and heal the sick! I could kill drug dealers to keep kids off of drugs, and steal money from my neighbor to fix my pickup truck and pay for school, etc. etc.

      I am not being selfish; I have nothing to lose here. Nobody is taking anything from me, so perhaps I should mind my own business. But I am not being selfish by insisting that people (and governments) should not steal things!

      I am NOT saying that the Swiss drug companies are not perhaps immoral for demanding a high price from a poor country. But likewise, if I want to buy something or rent something and think the price is unreasonable, that does NOT give me the right to take it -- or you, or your government.

      -Omar

    2. Re:Have you ever travelled? by Rivabem · · Score: 1

      Let me put it.
      Brasil is not stealing nothing, for the simple reason that, in the brazilian law IS PERFECT LEGAL. ( a law which Roche knew and agreeded in the time they began to sell their products in Brasil).

      I just read a text on a online newspapper saying that Roche is trying to renegotiate whith brazilian govt, what makes me think that it's not interesting to Roche to lose the power to sell nelfinavir to the government plan (but can sell to commom people, 100% of people are able to receive the drugs for free, but some who can afford them buy it, maybe conscious that someone else who need those drugs can't).

      But it also lights me to the fact that Roche could be complaining to WTO if it had the minimum expectation of victory...

      Brazil is using it's law not for fucking up the drug companies, but for not fucking up it's ppl.

      It's more a "see i can do this if you don't help, but if you help, we forget all tis stuff.."

      I'm sure Roche can and will make a great new price for their product (i read that they'll even give the pediatric version FOR FREE).

    3. Re:Have you ever travelled? by omarius · · Score: 2
      I think that's fantastic. It's wonderful what people can accomplish through negotiation and commerce. I am glad that both parties are willing to renegotiate this deal, rather than simply being hateful to each other.

      -Omar

  295. F Merck, F Patents by Anonymous Coward · · Score: 0

    and F-You if you don't "get it"

    Brasil is their own F-in country for cyring out loud. They don't need to respect some company's patents. If you had your own country you wouldn't have to fear the RIAA or MPAA or Merck either.

    At least someone has the balls to do what is right. God knows if it were up to America (which really means the corporations) we'd still have polio.

  296. Re:India, Brazil, China... half the planet already by sexy_princess69 · · Score: 1

    Finally, someone actually gets it.

  297. The one major flaw by Loundry · · Score: 1

    Our "sexual freedom" destroys families. It ruins lives. It transmits disease. It encourages disloyalty, dysfunction, and distrust.

    The big problem with people who think that STDs are good is this: ANY kind of human contact can transmit a disease. Touching, talking, kissing, sharing eating utensils ... all of these can be potentially deadly actions.

    So, using your logic, we can rewrite your argument like this:

    Our "freedom in human contact" destroys families. It ruins lives. It transmits disease. It encourages disloyalty, disfunction, and distrust.

    Furthermore, your argument is not unilaterally true. I can rewrite your statement like this, except this time the statement is true:

    Our "sexual freedom" does not always destroy families. It does not always ruin lives. It does not always transmit disease. It does not always encourage disloyalty, nor disfunction, nor distrust.

    Your argument is crap. I claim that there is nothing inherently morally wrong with consensual sex. If you disagree, then be prepared to show your evidence why.

    --
    I don't make the rules. I just make fun of them.
    1. Re:The one major flaw by grammar+fascist · · Score: 2

      ANY kind of human contact can transmit a disease. Touching, talking, kissing, sharing eating utensils ... all of these can be potentially deadly actions.

      Our "freedom in human contact" destroys families.

      I claim that there is nothing inherently morally wrong with consensual sex.

      Actually, you were busy claiming that I was arguing against human contact. I saw no arguments about morals. That's the problem with you people - you focus way too much on the physical aspect of everything.

      Our "sexual freedom" does not always destroy families. It does not always ruin lives. It does not always transmit disease. It does not always encourage disloyalty, nor disfunction, nor distrust.

      Sure. I'll agree. However, I wasn't saying that all of those things always happened. I was saying that your chances of destroying families, ruining lives, and encouraging disloyalty, dysfunction, and distrust are significantly higher. In fact, the more you do it, the higher your probabilities climb towards 1.

      Nothing inherently morally wrong with consensual sex? Tell that to the little boy whose dad ditched him because he just wanted to have fun with his mom when they got all hot and heavy at the drive-in. Tell that to the guys who wish their wives could sex 'em up like so-and-so did.

      Try to get that one past the parents who would like to teach their children some kind of morality.

      --
      I got my Linux laptop at System76.
    2. Re:The one major flaw by Loundry · · Score: 1

      Actually, you were busy claiming that I was arguing against human contact. I saw no arguments about morals. That's the problem with you people - you focus way too much on the physical aspect of everything.

      I never claimed that you were arguing against human contact. I claim that your logic can be used to argue against human contact. And you've also handed me a "you people" comment. Personal comments like these do not belong in this discussion.

      Sure. I'll agree. However, I wasn't saying that all of those things always happened. I was saying that your chances of destroying families, ruining lives, and encouraging disloyalty, dysfunction, and distrust are significantly higher. In fact, the more you do it, the higher your probabilities climb towards 1.

      You said no such things. Your exact quote was this: "Our 'sexual freedom' destroys families. It ruins lives. It transmits disease. It encourages disloyalty, dysfunction, and distrust." You never said that the chances were higher.

      Furthermore, let's continue with your logic. The cahnces of destroying families, ruining lives, encouraging disloyalty, dysfunction, and distrust are all significantly higher with all human contact. Why do you not make that argument, too?

      Nothing inherently morally wrong with consensual sex? Tell that to the little boy whose dad ditched him because he just wanted to have fun with his mom when they got all hot and heavy at the drive-in.

      The sex is not the problem. The problem here is that the parent is not taking care of their kid. What if the parents had ditched their little boy because they wanted to go ride a roller coaster? Would you then argue that there was something wrong with riding roller coasters? Of course not. Sex is an activity like any other, and raising children takes precedence in importance over all other activities. There is still nothing inherently wrong with consensual sex, just as there is nothing inherently wrong with riding roller coasters.

      Tell that to the guys who wish their wives could sex 'em up like so-and-so did.

      Okay! "Hey 'guys who wish your wives could sex you up like so-and-so did': there is nothing inherently wrong with consensual sex."

      I'm interested in knowing why you think there is something wrong with consensual sex. So far, you have not been very convincing.

      --
      I don't make the rules. I just make fun of them.
  298. You�re DEAD wrong !!!!! by PCHell · · Score: 1

    The drugs are not intended for SALE. Theyll never be sold. Its produced in government-owned labs. The Brazilian government gives it away for FREE.

  299. Re:This is an excellent thing to cheer... NOT by Anonymous Coward · · Score: 0
    > Wealth redistribution (whether material or
    > intellectual) is robbery, pure and simple.

    Damn right, and that's why teachers should be entitled to decide what their students do with all the intellectual wealth that was redistributed to them. </irony>

    Ideas cannot be redistributed, only spread. If I get to know what you know you don't suddenly forget about it, we both know it. The wealth only arises out of the artificial scarcity that prohibits me from using your ideas. The summed natural worth of ideas would be maximal if everybody knew them and could use them. The question is if this unhindered distribution would cause some ideas to not come up, and if that is worth _making_up_ IP-laws. The people who did it thought so. Perhaps they are right, perhaps not, I'm not sure. But don't pretend it's simple unless you realy think it's your natural right to force me to do with _my_ knowledge what _you_ want, only because you knew it first.
    And, sorry, but I think people who insist that such thought-control is their natural right need to have their asses kicked.

  300. The Human Body by nathanh · · Score: 2

    There's a rather good BBC production called The Human Body. One of the episodes looked into the development of ethics. The ethical problem was "should you steal drugs to save your dying <familymember/>".

    Children aged 8-9 inevitably said "no". The concept of stealing (to them) was totally wrong and there was no justification for it.

    Children aged 12+ were less decisive. In an ethical judgement between death and theft the children agreed that theft is the lesser evil.

    So it's depressing to discover how many people here have the ethical development of an 8 year old.

    1. Re:The Human Body by Anonymous Coward · · Score: 0

      We can only hope they're actually 8 years old.

      It blows my mind how many people seem to truly believe that PROFIT is the only motivation to do anything worthwhile.

      "Pure capitalism on this scale is not sustainable."

  301. Advocate of the devil? by Drashcan · · Score: 1
    Two things come to mind:
    • To those hinting at the high costs of pharma research: recently an article in The Economist or was it in the Financial Times, none of which are particularly anti-corporate, stated that a substantial slice of pharma research, especially the most risky research in terms of return on investment (like the research into anti-AIDS medicine), is government funded.
    • To those thinking free/cheap provision of AIDS drugs is effective:
      1. there is still no cure for AIDS. The drugs discussed just postpone for the sero-positive the outbreak of AIDS. But it disease and subsequent death remains unavoidable.
      2. subsequently, and especially if you consider the bad financial situation of many a developing country in which AIDS is sweeping entire generations (Brazil is still well of in this aspect; take a look at [South-]Africa!), SPENDING MONEY ON TEACHING SEXUALLY SAFE BEHAVIOUS AS WELL AS PROGRAMS OF FREE NEEDLE EXCHANGE FOR DRUG ADDICTS ARE THE ONLY FINANCIALLY AS WELL AS PRACTICALLY EFFECTIVE CURES!


      Drashcan

    --
    The nice thing about Windows is: it does not just crash; it displays a nice little dialog box and let's you press 'OK'
  302. CNN article is incomplete by Anonymous Coward · · Score: 0

    and totaly biased.

    As most of you stated Brazilian government is breaking the law, which is plain wrong, it's using the full extent of the contry's law.

    Some points did not get explained or shown on this thread:

    -There are about 17 drugs on the AIDS coquetel, about 11 are royalty free and generic are produced by local pharmaceutical companies for less than 30% of the big companies prices. The remaining drugs were been bought from roche and others, accounting for more than 70% of the costs.

    -The Brazilian patent laws allow the goverment to provide these patents to other companies given the new prices are much lower. Local companies are producing roche's drugs about 4 times cheaper and they make a lot of profits.

    -This is saving Brazilian government about 250Milhons USD a year.

    -India is doing this very same for years, with more drugs. To me seens like the drugs companies are trying to make Brazil the scape goat to avoid any other poor nation to do the same.

    -US government have allready threated Brazilian's to stop that or will create a comertial barrier to Brazilian products. This is not big news, this have been done with other countries, regardless global trade agencies saying that this would be ilegal.

    The big battle is not about the patents broken, but with the Brazilian IP laws, which are offencive to the US government, soo fair it was the only country to say soo.

    Talking about threatening, the US government is demanding all countries that plan to join the FTAA (Free Trade Area of the Americas) to create a law on the models of the DMCA, even if this means that current laws should be revogated.

    This is old news and the way the US government is mananging the situation is the same for all its international afairs "Do our way or we'll make sure you are out of business very soon", a politics adopted by it's local companies btw.

    And sorry for the many english mistakes, I'm not from an english speaking country.

  303. 1998 ! by camadas · · Score: 1

    Read the period. It's 3 years ago.

  304. ripoffs breed ripoffs... Karma is a bitch hey... by Anonymous Coward · · Score: 0

    poor Roche

  305. Too true... by FatSean · · Score: 1

    Looks like I'll just climb back up into my 'Ivory Tower'.

    --
    Blar.
  306. Re:2 Billion R&D == 5 Billion profit by decefett · · Score: 1
    9.61% operating profit: i.e., Roche was 3.64 times as profitable.

    Something that makes me sick about the current system (FWIW I consider myself a capitalist) is that investment flows to companies with the highest profit margin.

    Why does this make me sick? Because there are industries with artificially high profit margins because of government protection. In this case it's drug companies but many industries that fall under the banner of "Intellectual Property" have these artificially high margins.

    If company X who trades in IP (with govt granted monopolies) can make 3-4 times the profits of company Y who trades real world goods and services, investment is obviously going to flow to company X and others like it.

    This undermines what makes capitalism work, competition.

    --
    Australian? Join EFA
  307. Europeans Gave the World AIDS by queenb**ch · · Score: 1

    Since do-gooders in what was then the Belgian Congo decided to make their own polio vaccine from the local chimp and monkey popluation, which just happened to be infested with SIV (the ape equivalent of AIDS), they injected literally thousands of humans with SIV until the virus finally mutated and became HIV aka AIDS. I say that they should pay for the treatment of everyone on the planet with AIDS. They started it. Let them mop up the consequences.

    --
    HDGary secures my bank :/
  308. While it is sad to see by einhverfr · · Score: 2

    One must remember that the root purpose of patents is to promote the public good. In certain circumstances, I think that governments are completely justified in breaking patent protections in order to deal with major issues.

    that being said, I think that if the government can afford to, emminant domain makes more sense than all-out infringement. But it may not be an option for Brazil.

    --

    LedgerSMB: Open source Accounting/ERP
  309. Re:Imagine that...with a PORSCHE! by Anonymous Coward · · Score: 0

    Suppose the drug companies introduce a cure that requires an additive, like filings obtained from the steering wheel of a 2001 Porsche Boxster.

    Now Mr. Brazil says, "Well, yes, this is real stealing, but we still have to fight AIDS. Actually, we're working on only stealing cars and using the money to buy many different drugs that we need desperately. With this type of specialization we can cut the crime rate...to just auto theft. We're working on many different programs."

  310. Re:What a fucking disaster @ by Anonymous Coward · · Score: 0

    In principle, I agree with you. But really, what else could the government of Brazil do? Ethicaly you may be correct. Economically you may be correct. Legally, you may be correct. But politically, there?s no way a foreign government is going to get away with telling millions of it?s citizens they're going to die because of some US IP law. That's just reality.

  311. The US of A started this trend by gotan · · Score: 2

    In fact the United States didn't honour copyright either, they only did so at the beginning of the 20. century. So many popular works were blatantly copied in the USA and the Government didn't even do as much as raise a finger about that. So the USA only began to be concerned about international IP-Laws, when it fit their bill, and when the US american business would profit from it.

    Sorry, i don't see anything wrong, with other countries making their own laws with regard to IP-laws. Especially regarding the current state of US american IP-legislation (apparently the product the USA are most eager to export). Maybe it will help to create more sensible international IP-legislation, but most of all, it'll help to break monopolies built solely on ip-laws. Such monopolies are not a good thing, the restrictions of IP-legislation like the DMCA does more harm than good to international R&D.

    Where before the industry, the science and the technical knowledge was employed to establish the status quo and cheat 'poorer' countries out of their rich natural resources, now IP-laws are put to work. Japan did the right thing, when they decided 'learn' from other countries to bootstrap their industrial revolution about 1980. Why shouldn't other countries now do the same. Why should these countries consider themselves bound by legislation that originated in the USA and mostly benefits other countries, not them? Why adopt and enforce laws, that hurt their own business?

    --
    "By the way if anyone here is in advertising or marketing... kill yourself." -- Bill Hicks
  312. It's NOT illegal, it's compulsory licensing. by pompomtom · · Score: 1
    Basically Brazil breaks the agreed internation law and makes the stuff for free


    Bullshit. It's not illegal, it's compulsory licensing and it's allowed under the same international treaties that make the patent valid.

    Apparently people are willing to allow those with the guns to do it,


    Which has always been the way governments are created... through the legitimated monopoly on the means of violence.
    --

    Buckets,

    pompomtom

    "There's an exception to every rule. Except for some rules"
  313. GO BRAZIL GO! by Anonymous Coward · · Score: 0

    The America is losing it's status of state of liberty by each day that goes.. the DMCA, **AA, Echelon, Carnivore, Tempest...

    I'm not saying Brazil will be the new symbol of freedom, I'm just saying America is not free since A LONG time ago.

    Way to go Brazil! Now, if we could only do the same on Africa...

  314. Drug Companies Spend Unnecessarily by Anonymous Coward · · Score: 0

    You have to remember, many drug companies now spend nearly as much or more on media advertising than they do on actual drug research! Cut out the advertising and you can lower your prices to something reasonable! We are paying for their ads more than their research! Advertising for perscription drugs seems idiotic, especially those ones where they only give the name of the drug and not its use or vice versa (this is set by regulation, they can either give the name, or what it does, but not both without having to list the side-effects).

    Also, on a side note, much of the research is now done in collaboration with university labs, and many med schools are heavily supported by nature of being attached to these patents.....

  315. Good-Samaritan laws by bgeiger · · Score: 1

    First of all, could you quote chapter and verse regarding the law you mentioned?

    IIRC, some cities have mandatory assistance laws, but generally it's not required.

    Remember that the US is a collection of fifty states, which is each a collection of a number of counties, which is each a collection of a number of cities and townships. Each level has its own government, and each level can create its own laws.

    (Case in point: the drinking age is not a federal law. It's law in all fifty states, but it's not federal law. Basically, the federal government said, "Raise your drinking age to 21 or we won't give you any money for roads" and the states capitulated. But it's not a federal law.)

    Anyway, my second point: most areas have "good-samaritan laws", protecting people that help victims. IMNSHO, that's the better route to go: don't force people to help, but don't penalize them for trying.

    You need to get your facts straight before telling us to get ours straight.

    For the defense of Liberty: Soapbox, Ballot box, Jury box, Ammo box. Use in that order.

    --
    o/~ All God's children shall be free in Pirates of the Caribbean, when we reach that Magic Kingdom in the sky... o/~
    1. Re:Good-Samaritan laws by bgeiger · · Score: 1

      Argh.... previews don't show the .sig anymore?

      --
      o/~ All God's children shall be free in Pirates of the Caribbean, when we reach that Magic Kingdom in the sky... o/~
  316. good for Brazil by nabucco · · Score: 1

    Most of the research for these drugs are done by the government and universities, and then are just handed over, free of charge, to the drug companies. This "it will stop R&D" is BS, the majority of the R&D work is publically funded, although the profit on it is capitalized among a select few.

  317. Buying the patent by kinkie · · Score: 2

    It's a paradoxycal situation. The point here is that somebody somewhere is treating human lives as monetary value, which doesn't strike me as very ethically appleasing.

    Maybe there _is_ a manner to settle this, and it's actually so simple that I'm surprised nobody evern mentioned it.
    Some UN-funded agency could simply BUY the patents for some life-saving drugs from the holders (thus ensuring proper compensation for the development) and then license them free-of-charge to anybody willing to produce them (thus ensuring price-lowering via free market competition), or even just putting the patents in the Public Domain.

    Sure, such an UN agency would probably be a big drain on UN funding, but I as a citizen of a "developed" country am willing to give some of my tax money for such ethically-compelling matters, and I am sure many others would agree.

    --
    /kinkie
  318. yeah, great idea by Anonymous Coward · · Score: 0

    How many billions of dollars did Roche make last year? Don't be such a fucking idiot. You probably think Microsoft is going to close up doors too, since I just downloaded a pirate version of Windows.

    Oh yeah, and how much money was Roche making off Brazil that they won't anymore? Like 1% of their total revenue? Less? Yeah, so STFU.

  319. nice slippery slope by crayz · · Score: 1

    Logical fallacies are so much fun. You are arguing that we throw away the lives of millions for some hypothetical dystopian future where all pharm corps go out of business.

    There are already many countries around the world with more socialized health care, and apparently drug companies still feel it profitable to sell their wares in those countries. I don't recall hearing that Pfizer was pulling out of Canada, do you?

  320. boy... by crayz · · Score: 1

    This sure does sound like bullshit FUD when you consider what a small percentage of their revenue goes to R&D, and what huge profits they make. So what if the shareholders get a few less $, you really think they'll stop making drugs?

    What you don't seem to understand is that they weren't making jack of Brazil in the first place. Brazil can't pay it. It's like when Adobe goes around saying how they lost $10 trillion from all the fucking college kids who pirate Photoshop. Wrong. None of those kids have the money or desire to pay the $700 for Photoshop, and if they weren't able to warez it they'd just use MS Paint and deal with it. Adobe lost nothing. And neither did this drug company.

    So stop your damn chicken little act and open your eyes to the fact that Brazil is extending/improving the lives of millions of its citizens with essentially no negative consequences for the poor mistreated multinational pharm corps.

  321. Chomsky on the pharmaceutical industry by Anonymous Coward · · Score: 0
    If you're interested.

    "Other countries can produce the drugs. And under earlier patent regimes, you had process patents. I don't even know if those are legitimate, but process patents meant that if some pharmaceutical company figured out a way to produce a drug, somebody smarter could figure out a better way to produce it because all that was patented was the process. So, if the Brazilian pharmaceutical industry figured out a way to make it cheaper and better, fine, they could do it. It wouldn't violate patents. The World Trade Organization regime insists instead on product patents, so you can't figure out a smarter process. Notice that impedes growth, and development and is intended to. It's intended to cut back innovation, growth, and development and to maintain extremely high profits."

  322. Influence would be worse under socialism... by Anonymous Coward · · Score: 0
    Even if medical research were funded by society as a whole, we would still have the problem. It's obvious.

    After all, you are completely correct that we overspend on AIDS research relative to, say, malaria. However, US political groups are a big part of the reason that we do that. There are pressure groups that want research into some disease (AIDS, breast cancer, whatever), and they lobby the government for more funding based on that. It's understandable, given that they suffer from the disease, but it's just as unfair.

    It's absolutely ridiculous to think that political power wouldn't affect research decisions under a completely government-funded system, considering that right now political power drives government research on diseases.

    1. Re:Influence would be worse under socialism... by GregWebb · · Score: 1

      Two important words in my post there:

      in theory

      In practice this distorts it to some level. I'd say not as much, but it's still there.

      Isn't it lovely to have a bright, considerate and informed electorate who care about the world as a whole as opposed to their own small corner at the expense of all else? :(

      --

      Greg

      (Inside a nuclear plant)
      Aaaarrrggh! Run! The canary has mutated!

  323. Re:Newsflash! Slashdot readers readily hand over t by 3am · · Score: 1

    You named 2 - they're dominant corporations in their fields. i assure you that some decent companies are suffering, and the really awful ones are dead/on their way out.

    and microsofts stock value isn't were it is because of any great performance on their part (not bad performance, but not great). it is their because they are seen as stable, which comes at a premium in the stock markets these days.

    --

    A: None. The Universe spins the bulb, and the Zen master merely stays out of the way.
  324. Roche May Strike Deal With Brazil by nutznboltz · · Score: 1
    ZURICH (Reuters Health) Aug 23 - Swiss healthcare group Roche Holding AG sought to head off a fresh debate over the pricing of AIDS drugs in the developing world by insisting on Thursday that it was close to a cut-price deal with Brazil.

    Stunned by Brazil's threat to break a patent on Roche drug nelfinavir (Viracept), and to make the medicine in a state factory at a fraction of the cost, Roche said an accord was within reach to cut its discounted price for Viracept even more in 2002.

    "We were extremely surprised to hear the news...because we have been in a long-standing relationship with the Brazilian government, which has been particularly committed to active programmes to handle AIDS in Brazil," a Roche spokesman said. Roche now sells Viracept, whose patent is held by US firm Pfizer Inc., at less than half the US wholesale price in Brazil and has offered a steeper discount in 2002, he added.

    "We are very close to reaching an agreement which is based upon a further, additional discount," spokesman Daniel Piller said. He said Basel-based Roche also intends to start manufacturing Viracept tablets in Brazil next year and to continue to provide Viracept syrup free of charge to Brazilian children with AIDS.

    Brazil's health minister, Jose Serra, said on Wednesday he had started the process of issuing a compulsory license to make Viracept at a Brazilian factory after failing to obtain sufficient price concessions from Roche. Under Brazilian law the government can issue a compulsory license to make a patented drug when a "national emergency" is invoked.

    If the plan proceeds, it may be the first patent violation of an AIDS drug in the world and make the medicine available at lower prices in Brazil early next year.

    The Brazilian dispute could eventually spread to include US officials, who filed a complaint against Brazil's patent law with the World Trade Organisation earlier this year, then withdrew it under pressure from world leaders and health organisations who praise Brazil's aggressive response to AIDS.

    "We understand that any decision to declare a compulsory license requires the communication of this decision to the US Trade Representative. This was something which was agreed between the Brazilian and US governments in July 2001 and that is also a reason why we were surprised," Piller said.

  325. Cipla Launches 3-in-1 Antiretroviral Pill by nutznboltz · · Score: 1

    BOMBAY (Reuters Health) Aug 06 - Indian drugmaker Cipla Ltd said on Monday that it has launched the first three-in-one tablet to treat HIV infection that contains the antiretroviral drugs stavudine, lamivudine and nevirapine.

    Cipla, which shot into international prominence in February by offering to supply combination antiretroviral therapy for less than $1 a day, said in a statement that a month's supply of the new pill, Triomune, would cost patients $38.21.

    The company statement said the price represented a five- to six-fold reduction in the monthly cost of therapy. The new product is the first to combine the three antiretroviral drugs in one tablet, which has not been available because the patents for these drugs are controlled by different companies.

    Britain's GlaxoSmithKline holds the patent on lamivudine, Germany's Boehringer Ingelheim has the patent on nevirapine and US drug giant Bristol-Myers Squibb holds the patent on stavudine.

    Cipla is permitted by Indian patent law to make drugs that are patented by other companies internationally because the law protects only the processes by which drugs are made, and not the drugs themselves. This means Indian companies can make drugs under patent in the West, provided they use a process that is different from the original.

    In February, the company offered to supply the three drugs to the international charity Medecins Sans Frontieres for $350 per patient per year, a thirtieth of the US price.

    1. Re:Cipla Launches 3-in-1 Antiretroviral Pill by nutznboltz · · Score: 1

      Cipla, which shot into international prominence in February by offering to supply combination antiretroviral therapy for less than $1 a day, said in a statement that a month's supply of the new pill, Triomune, would cost patients $38.21.

      The sad fact is that this is an export price. People in India are expected to pay more than this for the drug.

  326. BMS ddI and Thailand by nutznboltz · · Score: 2, Insightful

    The U.S. Government did all the R&D for ddI. They could not market it so they used some selection process to license it to Bristol Meyers Squibb (BMS) for ten years. BMS turns around and goes for the jugular when Thailand tries to klone ddI. Eventually this happened:

    -----

    * Date: Mon, 17 Jan 2000 19:47:24 -0500 (EST)

    THAILAND WILL PRODUCE GENERIC DDI POWDER

    The Thai Ministry of Public Health today announced that it will not apply compulsory license but that it will let the Government Pharmaceutical Organization (GPO) produce the powder of ddI. About 100 activists had gathered outside the Ministry of Public Health to hear the decision of the Public Health Minister.

    ddI powder is not patent protected in Thailand. One sachet will cost $0.7 (equivalent to 150 mg); daily cost will therefore be $ 1.4 compared to currently about $ 3.7 No generic tablets will be available because of the patent.

    The problem with ddI is the expensive raw material because there is only one relatively small supplier in Canada. Raw material from a Japanese producer is only 55% of the cost but this is the BMS supplier and BMS has prevented the company from selling to other customers. If BMS would be interested to actually do something for people they could offer ddI at a daily cost of probably less than $ 1.0!

    No discount for the BMS product has been announced so far.

    There are many open questions:

    As reason for not applying compulsory license the Ministry of Public Health quoted fear for a BMS law suit and lacking support from the Dept of Intellectual Property. The Dept. of Intellectual Property said that they were "worried" to use compulsory license but refused to name reasons. Several activists questioned why compulsory license is in the law if it can not be used.

    The Public Health Minister was asked why ddI powder was not produced already two years ago; he replied that he was not yet Health Minister at that time.

    The NGO network had demanded compulsory license for ddI since last year and had also demanded the production of ddI powder as an interim solution. NGO representatives will meet with the US ambassador to Thailand tomorrow, Tuesday to hand over a letter to President Clinton asking for a statement that the US government will not interfere if Thailand uses compulsory license for ddI.

    Tido von Schoen-Angerer, MD
    MSF Thailand
    msfdrugs@asianet.co.th-th-th-end
    (remove "-th-th-end" to reply)

  327. Patents help everyone in the long run by GPS+Pilot · · Score: 1
    what good is R&D and new drugs and technologies if only x% of the world can take advantage of developments supposedly in the name of 'humanity'?

    Drugs aren't developed in the name of humanity, they're developed for the benefit of stockholders. The fact that they also benefit humanity is fortuitous gravy. You may think that is a cold system, but it is a system that has worked exceedingly well. It is a system that has discovered hundreds of miraculous treatments.

    In 20 years the patent will expire and then the third world country can start making the drug.

    When patents are honored, we have the first world nations getting the benefit of the drug for 20 years, followed by everyone getting the benefit of the drug.

    When patents are not honored, we have nobody getting the benefit of the drug because it's never developed in the first place.

    You tell me which scenario is better.

    --
    That that is is that that that that is not is not.
  328. Why is this nonsense moderated so high? by Snaller · · Score: 1

    nt

    --
    If Google really cared they would fix Android Chrome to reflow text, instead of discriminating
  329. Brazil is within its legal rights by DABANSHEE · · Score: 1

    Brazil is breaking no laws. The treaty gives any nation the ability to disregard foreign patent laws if they invoke a national emergency, OR invoke the health of their citizens.

    Beside if a nation isn't in the WTO or leaves the WTO, they need not have any patent laws in their country.

    Look at all those Asian countries that only introduced WTO complient Copyright/Patent/Trademark laws, about 5 years ago.

  330. Well that's Brazil's right to decide by DABANSHEE · · Score: 1

    If they decide that unbridled capitalism isnt the way to go & instead decide like the majority of the world that they'd prefer a mixed economy taking policies from both the left & the right, on the basis of what they think is the best policy for the job at hand; that's their right.

    They can even decide to leave the WTO & have no patent/copyright/trademark laws if they want. Afterall the world did just fine before such laws existeed too.

  331. That's their right by DABANSHEE · · Score: 1

    If their country's law permit them to do that.

    Afterall businesses only exist to make a profit.

    If you beleive its unfair, you can always lobby your own goverment to repeal its patent laws so corporations in your country could then do it do.

    Afterall Brazil is only looking after its own interests.

    Brazil's govt doesn't exist to protect US interests, or does it.

  332. More numbers. by KnightStalker · · Score: 2

    Stupid jackass... are you too terrified to go to web sites on your own? How about Pfizer:

    Selling, informational, and administrative expenses: $11,442,000,000
    R&D expenses: $4,435,000,000

    Merck?

    $6 billion on marketing, $2 billion on R&D.

    GlaxoSmithKline? They call themselves a "research company"...

    $10 billion on "selling, general, and administrative"
    $3.8 billion on R&D.

    I still can't find information on what Bayer spent on marketing.

    All this information is from the companies' annual reports, available for free on their web sites, and this is hardly damning evidence that corps are evil. But it's pretty clear that they do spend way more on marketing than on development.

    --
    * And remember, it's spelled N-e-t-s-c-a-p-e, but it's pronounced "Mozilla."
  333. Re:This is an excellent thing to cheer... NOT by speedbump · · Score: 1

    Bah, you are an 'intellectual communist'.

    Your argument about students being precluded from benefiting from the information imparted by teachers doesn't apply: school is not an economic stage, although it certainly prepares the actors for same.

    If I take 20 years of my life researching a new way to smelt metal that results in extraordinary materials advances, why should you, who have done nothing but sit on your ass and play Nintendo, get a cut of that invention?

    I won't argue that intellectual property is much more difficult to judiciously manage when we are talking computer programs and processes, thus we probably can't realistically protect those types of IP. But I have laugh at the thieving weenies who think it is their right to steal music or video (usually the product of a team of talented artists) just because they don't wanna pay the price demanded for it.